Methods for treating, preventing and predicting risk of developing breast cancer

ABSTRACT

Methods for treating, preventing and predicting a subject&#39;s risk of developing breast cancer are provided.

RELATED APPLICATIONS

The present application is a continuation of U.S. patent application Ser. No. 14/414,674, filed Jan. 13, 2015, which is a U.S. National Stage patent application of International Application No. PCT/US2013/032384, filed Mar. 15, 2013, which claims the benefit of U.S. Provisional Patent Application Ser. No. 61/672,973, filed Jul. 18, 2012. The contents of all the prior applications are herein incorporated by reference in their entireties.

STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT

This invention was made with government support under grant numbers P01 CA117969, P50 CA089383, P01 CA080111, CA116235, CA087969, awarded by the National Institutes of Health and grant number W81XWH-07-1-0294 awarded by the Department of Defense. The government has certain rights in the invention.

TECHNICAL FIELD

Methods for treating, preventing and predicting a subject's risk of developing breast cancer are provided.

BACKGROUND

Breast cancer is the most common type of cancer among women in the United States, accounting for more than a quarter of all cancers in women. Approximately 2.5 million women in this country are breast cancer survivors, and an estimated 192,370 new cases of breast cancer were diagnosed in women in 2009. Further, estrogen receptor positive (ER+) postmenopausal breast cancer is the most common form of the disease. While advances in treatment have enabled more women to live longer overall and to live longer without disease progression, what is needed in the art are methods for identifying subjects at risk of developing breast cancer before they develop it, and for preventing the development of the disease altogether. Presently, however, very few reliable predictive markers for identifying subjects at high risk for developing breast cancer, such as ER+ or ER− breast cancer, are known.

BRCA1 and BRCA2 mutations are examples of predictive markers that have been correlated with an increased risk of developing breast cancer; however, only 5-10% of breast cancers are thought to be caused by inherited abnormalities in BRCA1 and BRCA2 (i.e. hereditary breast cancer). The remaining approximately 90-95% of all breast cancers are sporadic. Thus, what is needed in the art are novel markers that are useful for identifying subjects having an elevated risk of developing breast cancer, as well as novel targets of breast cancer therapies.

SUMMARY OF THE INVENTION

As follows from the Background section above, there remains a need in the art for methods for predicting a subject's risk of developing breast cancer. Such methods, as well as other, related benefits, are presently provided, as discussed in detail below.

In one aspect, a method of predicting a subject's risk of developing breast cancer is provided, wherein the method includes: (a) determining the frequency in a breast tissue sample of CD44+, CD24− breast epithelial cells, and (b) predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of CD44+, CD24− breast epithelial cells is decreased compared to a first control frequency of CD44+, CD24− breast epithelial cells; or (c) predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of CD44+ breast epithelial cells is increased compared to a second control frequency of CD44+, CD24− breast epithelial cells.

In another aspect, the method further includes determining the frequency of CD24+ breast epithelial cells. In one aspect, step (b) includes predicting that the subject has a relatively elevated risk of developing breast cancer if: (i) the frequency of CD44+, CD24− breast epithelial cells is decreased compared to a first control frequency of CD44+, CD24− breast epithelial cells, and (ii) the frequency of CD24+ breast epithelial cells is increased compared to a first control frequency of CD24+ breast epithelial cells; and step (c) includes predicting that the subject has a relatively reduced risk of developing breast cancer if: (i) the frequency of CD44+ breast epithelial cells is increased compared to a second control frequency of CD44+, CD24− breast epithelial cells, and (ii) the frequency of CD24+ breast epithelial cells is decreased compared to a second control frequency of CD24+ breast epithelial cells. In another aspect, step (b) includes: predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of CD24+ breast epithelial cells is greater than the frequency of CD44+, CD24− breast epithelial cells in the sample; and step (c) includes predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of CD24+ breast epithelial cells is equal to or less than the frequency of CD44+, CD24− breast epithelial cells in the sample. In still another aspect, the subject is in need of such predicting.

In another aspect, a method of predicting a subject's risk of developing breast cancer is provided. The method includes: (a) determining the frequency in a breast tissue sample of cells of one or more types selected from the group consisting of p27+ breast epithelial cells, Sox17+ breast epithelial cells, Cox2+ breast epithelial cells, Ki67+ breast epithelial cells, ER+, p27+ breast epithelial cells, ER+, Sox17+ breast epithelial cells, ER+, Cox2+ breast epithelial cells, ER+, Ki67+ breast epithelial cells; androgen-receptor-positive (AR+), p27+ breast epithelial cells, AR+, Sox17+ breast epithelial cells, AR+, Cox2+ breast epithelial cells, and AR+, Ki67+ breast epithelial cells; and (b) predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of the cells of the type is increased compared to a first control frequency of cells of the type; or (c) predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of the cells of the type is decreased compared to a second control frequency of the cells of the type.

In certain aspects, step (b) includes predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of p27+ breast epithelial cells is 15 percent (%) or greater of the breast epithelial cells in the sample; and step (c) includes predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of p27+ breast epithelial cells is less than 15% of the breast epithelial cells in the sample. In other aspects, step (b) includes predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of p27+ breast epithelial cells is 20 percent (%) or greater of the breast epithelial cells in the sample; and step (c) includes predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of p27+ breast epithelial cells is less than 20% of the breast epithelial cells in the sample. In still another aspect, step (b) includes predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of p27+ breast epithelial cells is 25 percent (%) or greater of the breast epithelial cells in the sample; and step (c) includes predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of p27+ breast epithelial cells is less than 25% of the breast epithelial cells in the sample. In certain aspects, step (b) includes predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of Ki67+ breast epithelial cells is 2 percent (%) or greater of the breast epithelial cells in the sample; and step (c) includes predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of Ki67+ breast epithelial cells is less than 2% of the breast epithelial cells in the sample. In yet other aspects, step (b) includes predicting that the subject has a relatively elevated risk of developing breast cancer if: (i) the frequency of p27+ breast epithelial cells is increased compared to a first control frequency of p27+ breast epithelial cells, and (ii) the frequency of Ki67+ breast epithelial cells is increased compared to a first control frequency of Ki67+ breast epithelial cells; and step (c) includes predicting that the subject has a relatively reduced risk of developing breast cancer if: (i) the frequency of p27+ breast epithelial cells is decreased compared to a second control frequency of p27+ breast epithelial cells, and (ii) the frequency of Ki67+ breast epithelial cells is decreased compared to a second control frequency of Ki67+ breast epithelial cells.

In another aspect, a method of predicting a subject's risk of developing breast cancer is provided. The method includes: (a) determining the expression level in a breast tissue sample from a subject of at least one marker selected from the group consisting of p27, Sox17 and Cox2; and (b) predicting that the subject has a relatively elevated risk of developing breast cancer if the expression level of the at least one marker is increased compared to a first control level of the at least one marker; or (c) predicting that the subject has a relatively reduced risk of developing breast cancer if the expression level of the at least one marker is decreased compared to a second control level of the at least one marker. In certain aspects, the expression level determined is the mRNA expression level of the at least one marker. In other aspects, the expression level determined is the protein expression level of the at least one marker. In certain aspects, step (a) includes determining the expression level of at least two (2) markers or all 3 markers selected from the group consisting of p27, Sox17 and Cox2.

In some aspects, step (a) further includes determining the expression level of one or more additional markers having an expression level that is modulated in breast epithelial cells of parous women compared to the levels in breast epithelial cells of nulliparous women. In certain aspects, the sample is enriched for CD44+, CD24− breast epithelial cells or for CD24+ breast epithelial cells prior to the determining. In still other aspects, the sample is enriched for Ki67+ breast epithelial cells or CD44+ Ki67+ breast epithelial cells prior to the determining.

In certain aspects, the subject for whom the risk of developing an estrogen-receptor-positive (ER+) breast cancer is being predicted has a BRCA1 and/or a BRCA2 mutation.

In other aspects, a method of predicting a subject's risk of developing breast cancer is provided, which includes determining a parity/nulliparity-associated gene expression signature in a sample containing breast epithelial cells. In certain aspects, the sample is enriched for CD44+ cells, CD24+ cells, or CD10+ cells.

In one aspect, a method of predicting breast cancer disease outcome is provided, including testing for a parity/nulliparity-associated gene expression signature in breast cancer cells.

In another aspect, a method of treating estrogen-receptor-positive (ER+) breast cancer in a subject is provided. The method includes administering to the subject a composition that includes an inhibitor of a pathway that has increased activity in CD44+, CD24− breast epithelial cells of nulliparous women compared to the activity in CD44+, CD24− breast epithelial cells of parous women. In certain aspects, the pathway can be cytoskeleton remodeling, chemokines, androgen signaling, cell adhesion, or Wnt signaling.

In yet another aspect, a method of preventing breast cancer in a subject is provided. The method includes administering to a subject at risk of developing breast cancer an inhibitor of a pathway that has increased activity in breast epithelial cells of nulliparous women compared to breast epithelial cells of parous women. In some aspects, the pathway can be cytoskeleton remodeling, chemokines, androgen signaling, cell adhesion, or Wnt signaling. In certain aspects, the pathway includes a mediator molecule that can be cAMP, EGFR, Cox2, hedgehog (Hh), TGFβ receptor (TGFBR) or IGF receptor (IGFR). In still other aspects, the inhibitor selectively targets CD44+, CD24− breast epithelial cells, CD24+ breast epithelial cells, p27+ breast epithelial cells, or Ki67+ breast epithelial cells. In certain aspects, the cells selectively targeted by the inhibitor are also ER+. In certain aspects, the subject has a BRCA1 or BRCA2 mutation.

In certain aspects, methods of treating or preventing breast cancer in a subject are provided. The methods include administering to a subject an agonist of a pathway that has decreased activity in CD44+, CD24− breast epithelial cells of nulliparous women compared to CD44+, CD24− breast epithelial cells of parous women. In certain aspects, the pathway can be tumor suppression (Hakai/CBLL1, CASP8, SCRIB, LLGL2), DNA repair, PI3K/AKT signaling, or apoptosis. In certain aspects, the agonist selectively targets CD44+, CD24− breast epithelial cells, CD24+ breast epithelial cells, p27+ breast epithelial cells, or Ki67+ breast epithelial cells. In another aspect, the cells selectively targeted by the agonist are also ER+. In certain aspects, the subject has a BRCA1 or BRCA2 mutation.

In any of the above aspects, the breast cancer can be an ER+ or an ER− breast cancer.

Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In case of conflict, the present document, including definitions, will control.

All publications, patent applications, patents, and other references mentioned herein are incorporated by reference in their entirety. The materials, methods, and examples disclosed herein are illustrative only and not intended to be limiting.

The details of one or more embodiments of the invention are set forth in the accompanying drawings and the description below. Preferred methods and materials are described below, although methods and materials similar or equivalent to those described herein can also be used in the practice or testing of the present invention. Other features, objects, and advantages of the invention will be apparent from the description and drawings, and from the claims.

DESCRIPTION OF DRAWINGS

FIG. 1 contains representative FACS plots for cells stained with fluorescent antibodies specific for CD24 and CD44 from normal breast tissue of nulliparous (upper plot) and parous (lower plot) women.

FIG. 2 contains graphs plotting the frequency (%) of CD44+, CD24+, and CD10+ human breast epithelial cells relative to total human breast epithelial cells from nulliparous and parous women. 10 samples each from nulliparous and parous groups were analyzed, and each dot represents an individual sample. Error bars represent mean±SEM.

FIG. 3 contains dot plots showing a genome-wide view of genes differentially expressed between nulliparous (N) and parous (P) samples in CD44+, CD24− breast epithelial cells (upper left quadrant), CD10+ breast epithelial cells (upper right quadrant), CD24+ breast epithelial cells (lower left quadrant), and stromal fibroblasts (lower right quadrant). Each dot represents a gene. Fold differences between averaged N and P samples and their corresponding p-values are plotted on the y and x-axis, respectively. Vertical lines indicate p=0.05, numbers indicate the number of genes differentially expressed at p<0.05.

FIG. 4A is a three-dimensional projection of the gene expression data onto the first three principal components. Each ball is a different sample; cell type and parity are indicated.

FIG. 4B is a box-and-whisker diagram of the paired Euclidean distance for each of the indicated cell types: CD44+, CD24+, CD10+, and stromal fibroblasts (“stroma”). The middle line within a box represents the median value. The Box is the IQR (interquartile range, 25th and 75th percentile). The top and bottom line of each box plot is the data range: the lowest data still within 1.5 IQR of the lower quantile and the highest data still within 1.5 IQR of the upper quantile. Data shown outside the range are plotted as circles. The Kolmogorov-Smirnov (KS) test was used to determine the significance of difference between CD44+ and other cell types. Statistical significance (p) is indicated.

FIG. 5 is a box-and-whisker diagram of the paired Euclidean distance for the following pair-wise comparisons (from left to right on the x-axis): CD44+, CD24− nulliparous vs. CD10+ nulliparous; CD44+, CD24− nulliparous vs. CD24+ nulliparous; CD44+, CD24− parous vs. CD10+ nulliparous, CD44+, CD24− parous vs. CD24+ nulliparous; (N: nulliparous. P: parous). The middle line within a box represents the median value. The Box is the IQR (interquartile range, 25th and 75th percentile). The top and bottom line of each box plot is the data range: the lowest data still within 1.5 IQR of the lower quantile and the highest data still within 1.5 IQR of the upper quantile. Data shown outside the range are plotted as circles. The Kolmogorov-Smirnov (KS) test was used to determine significance of differences, indicated on the plot (p).

FIG. 6 contains dot plots showing the relative DNA methylation, as determined by qMSP analysis (left panel), and the expression, as determined by qRT-PCR (right panel), of the indicated genes (left panel: TTC9B, RRP15, and AOPKO5; right panel: CDKN1B, PTGS2, COL1A1 and COL3A1) in CD44+, CD24− breast epithelial cells and CD24− breast epithelial cells isolated from multiple nulliparous and parous women, respectively. Relative methylation and expression levels normalized to ACTB and RPL19, respectively, are indicated on the y-axis. The bars mark the median and p-values indicate the statistical significance of the observed differences.

FIG. 7 is a dendrogram showing the hierarchical clustering of Norwegian cohort (GSE18672) based on Pearson correlation using genes differentially expressed in CD44+ cells. Individual patient samples from the cohort are shown (MDG-110, MDG124, etc.); “N-pre” means premenopausal. Clustering analysis using the differentially expressed gene sets divided these samples into two groups, a mixed parous/nulliparous (Nulliparous A) group, and a distinct, nulliparous (Nulliparous B) group.

FIG. 8 is a bar plot of the scrum estradiol levels in picograms per milliliter for the samples corresponding to FIG. 7 (Nulliparous A, Nulliparous B and Parous groups).

FIG. 9A is a dendrogram showing the hierarchical clustering of CD44+ cells from parous and nulliparous control women and parous BRCA1 mutation carriers.

FIG. 9B is a dot plot showing the relative frequency of CD44⁺, CD24⁺, and CD10⁺ cells among all breast epithelial cells in samples from nulliparous and parous groups from control and BRCA1/2 mutation carriers. The error bars mark the mean±standard error of the mean (SEM).

FIG. 10 is a dendrogram depicting hierarchical clustering of signaling pathways significantly high in parous or nulliparous samples in any of the four cell types (stromal fibroblasts (“stroma”), CD10+, CD44+ and CD24+ breast epithelial cells) analyzed.

FIG. 11 is a heat map depicting unsupervised clustering of signaling pathways significantly down- or upregulated in parous compared to nulliparous samples in any of the four cell types (stromal fibroblasts (“stroma”), CD10+, CD44+ and CD24+ breast epithelial cells) analyzed. Gray scale indicates −log p value of enrichment. Rectangles highlight cell type-specific or common altered pathways.

FIG. 12 contains graphs showing the relative enrichment (left panel) and relative connectivity (right panel) of the indicated protein classes in nulliparous and parous samples in each of the four cells types (stromal fibroblasts (“stroma”), CD10+, CD44+ and CD24+ breast epithelial cells) analyzed. X-axes indicate −log 10 p-values for enrichment (left panel) with the listed protein classes and the number of overconnected objects, defined as proteins with higher than expected number of interactions, in each functional category within each group (right panel), respectively.

FIG. 13 is an integrated map of statistically significant (P-val<0.05) pathways enriched in genes highly expressed in CD44+ nulliparous cells along with DNA methylation patterns. Important pathways highly active in CD44+ nulliparous cells potentially regulated by DNA methylation include PI3K signaling and TCF/Lef signaling. Highly expressed genes, and promoter and gene body hypo and hyper-methylation are indicated.

FIG. 14 is an integrated map of statistically significant (P-val<0.05) pathways enriched in genes highly expressed in CD44+ parous cells along with DNA methylation patterns. Active pathways potentially regulated by DNA methylation in CD44+ parous cells include TGFB2 signaling. Highly expressed genes, and promoter and gene body hypo and hyper-methylation are indicated.

FIG. 15A is a Venn diagram depicting the number of unique and common pathways high in CD44+ nulliparous cells and in mammary glands of virgin rats, respectively.

FIG. 15B is a list of top common pathways downregulated in CD44+ cells and mammary glands from parous women and rats, respectively. Names of the pathways and p-values of enrichment are indicated.

FIG. 16 contains dot plots showing a genome-wide view of differentially methylated genes in CD44+ (upper panel) and CD24+ (lower panel) cells between nulliparous and parous samples. All MSDK sites are plotted on the x-axis in the order of p-values of the difference between nulliparous and parous samples in CD44+ or CD24+ cells. Log ratios of averaged MSDK counts in three N and three P samples are plotted on the y-axis. Vertical lines indicate p=0.01 and the numbers of significant DMRs (p<0.01) are shown in the upper and lower right corners of the plots.

FIG. 17 is a heat map showing the pathways enriched by genes associated with gene body or promoter DMRs in CD44+ cells from nulliparous and parous samples.

FIG. 18 contains graphs quantifying (in arbitrary units) the expression of p27, Sox17 and Cox2 in CD44+ and CD24+ breast epithelial cells in premenopausal nulliparous (NP) and parous (P) women. Horizontal bars indicate the median, vertical bars indicate SEM, and p-values indicate the statistical significance of the observed differences.

FIG. 19 is a graph showing the frequencies (% of total breast epithelial cells) of p27+ and Ki67+ cells in nulliparous (NP) and parous (P) breast tissue samples. Horizontal bars indicate the median, vertical bars indicate SEM, and p-values of differences between nulliparous and parous groups are indicated.

FIG. 20 contains graphs quantifying the expression of p27 (in arbitrary units) and the frequencies (% of total breast epithelial cells) of p27+ and Ki67+ cells in CD44+ and CD24+ breast epithelial cells in postmenopausal nulliparous (NP) and parous (P) women (FIG. 20 )

FIG. 21 contains graphs quantifying the expression of p27 (in arbitrary units) and the frequencies (% of total breast epithelial cells) of p27+ and Ki67+ cells in high and low density areas of the same breast from premenopausal parous women.

FIG. 22 contains bar graphs quantifying the frequencies (% of total breast epithelial cells) of p27+ and ER+ cells in each group of samples (nulliparous, parous, women in follicular or luteal phase of menstrual cycle, oocyte donor, early pregnancy, late pregnancy, BRCA1+ mutation carriers and BRCA-2 mutation carriers). Horizontal bars indicate the median, vertical bars mark the SEM, and asterisks indicate significant (p≤0.05, t-test or Fisher exact test) differences between groups of 4-8 samples.

FIG. 23A is a bar graph quantifying frequencies (fraction (%) of total breast epithelial cells) of p27+, androgen receptor (AR)+, and p27+AR+ cells in each set of samples (nulliparous, parous, and BRCA1+ mutation carriers).

FIG. 23B contains bar graphs quantifying frequencies (% of total breast epithelial cells) of p27+, Ki67+, and p27+Ki67+ cells in each set of samples (sample collected from women in the follicular or luteal phase of the menstrual cycle, oocyte donor and women in early pregnancy).

FIG. 23C contains bar graphs quantifying the frequency of p27+, Ki67+, and p27+Ki67+ cells in the breast tissue of premenopausal and postmenopausal nulliparous (NP) or parous (P) women in different phases of the menstrual cycle (i.e., follicular (“Foll”) and luteal (“Lut”)) or with breast cancer (BC) or without (cont); asterisks mark p≤0.05.

FIG. 24 contains bar graphs quantifying the frequency (% of total breast epithelial cells) of BrdU+, Ki67+, and p27+ cells in each of the indicated conditions (control, inhibition of cAMP, EGFR, Cox2, Hh, TGFβ, Wnt, or IGFR in normal breast tissues incubated in a tissue explant culture model with the relevant inhibitor); * indicates p<0.05 and bars indicate SEM.

FIG. 25 contains bar graphs quantifying the frequency (% of total breast epithelial cells) of pSMAD2+ cells, or the mean fluorescence intensity of pEGFR and Axin 2 in breast epithelial tissue treated with control (C) or inhibitor (I) (inhibitor of TGFb, EGFR or Wnt, from top graph to bottom graph).

FIG. 26A contains line graphs plotting the RGB spectra demonstrating overlap between the expression of p27 and the indicated marker (in the top panels: circles mark the line for pSMAD2, triangles mark the line for p27, and squares mark the line for DAPI; in the middle panels: circles mark the line for pEGFR, triangles mark the line for p27, squares mark the line for DAPI; in the lower panel: circles mark the line for axin2 and squares mark the line for DAPI); left graphs are control groups and right graphs are treated with the indicated inhibitor. In all graphs, intensity is plotted on the y-axis and distance (in pixels) in plotted on the x-axis.

FIG. 26B contains a bar graph quantifying the frequency (%) of p27+ cells in tissue slices from 3-4 independent cases treated with hormones mimicking the indicated physiologic levels (control, follicular phase, luteal phase, and pregnancy) in women. Asterisks indicated significant (p≤0.05) differences.

FIG. 26C contains bar graphs quantifying the frequency (% of all breast epithelial cells) of p27+, Ki67+, and p27+Ki67+ cells in tissue slice cultures treated with Shh or Tamoxifen; asterisks indicate a statistical significance of p≤0.05.

FIG. 27 contains Kaplan-Meier plots depicting the probability of breast cancer-specific survival among women with invasive ER+(left panel) or ER− (right panel) breast cancer by parity in the Nurses' Health Study (1976-2006). The p-value of the difference between the two survival curves overall was calculated with use of the log-rank test. Beneath each plot the number of parous and nulliparous women alive at each of the time points shown on the x-axes of the plots (beginning at 5 years) is shown.

FIGS. 28 and 29A-C contain heat maps (left panel) and Kaplan-Meier plots with their corresponding log-rank test p-values (right panel) showing a significant association of the presence of a parity/nulliparity-related gene signature with overall survival in the indicated cohorts of breast cancer patients with ER+ tumors. In each figure, the top heat map shows the signature from down regulated genes in parous subjects and the bottom heat map from up group genes. The bars above the heat maps indicate the two distinct patients groups separated by the co-expression of the signature (light gray (left bar on heat map, upper line on Kaplan-Meier plots): better survival group; dark gray (right bar on heat map, lower line on Kaplan-Meier plots): worse survival group). The bar at the right side of heat map, divided into an upper and lower group, indicates effect of parity on genes in breast cancer progression. The upper group indicates parity induces gene expression level change in the same trend as breast cancer progression. The lower group indicates parity induces gene expression level change in the opposite trend as breast cancer progression. Black bars (beneath the heat maps) indicate death. The genes shown in the heat maps (the parity/nulliparity-related gene signature) are shown in Table 18, below, which shows the gene symbol, gene description, gene expression pattern (i.e., high in parous and nulliparous samples), and prognostic values (good or bad prognosis) for each of the genes.

FIG. 30 contains a diagram showing the timeline for simulations in a mathematical model of the dynamics of proliferating mammary epithelial cells that can accumulate the changes leading to cancer initiation, run from the time of menarche at 12.6 years through cancer initiation or death at 80.9 years. The earliest time of pregnancy is at menarche; the latest time is right before menopause at 51.3 years.

FIGS. 31-33 are schematic representations of a mathematical model of the dynamics of proliferating mammary epithelial cells that can accumulate the changes leading to cancer initiation. In FIG. 31 , initially, there are N wild-type stem cells (top of schematic), which give rise to a differentiation cascade of 2^(z+1)−1 wild-type luminal progenitor cells (triangular, lower region). Darkening gray gradations refer to successively more differentiated cells and serve to clarify a single time step of the stochastic process. In FIG. 32 , “WT” means wild-type (non-mutated) stem cell and “f_(mut)” means mutant progenitor cell. Division during pregnancy is indicated by “z_(preg)”; z is the number of cell divisions; K indicates the number of cell divisions from the first progeny of the stem cell (k=0) to the terminally differentiated cell (darkest gray).

FIG. 34 is a bar graph quantifying the effect the indicated parameters of the mathematical model described in Example 10 (N value, Zpreg, and p) have on the relative probability of cancer initiation (per duct) relative to nulliparous women. The default values were: N=8, p=10⁻², z_(preg)=2.

FIG. 35 is a line graph plotting the likelihood (relative probability) of cancer initiation relative to nulliparous (y-axis) against time of first pregnancy after menarche (years) on the x-axis for the indicated starting number of stem cells (N=5, N=8, and N=10).

FIG. 36 is a line graph plotting the likelihood (relative probability) of cancer initiation relative to nulliparous (y-axis) against time of first pregnancy after menarche (years) on the x-axis for the indicated probabilities of stem cell differentiation (p=0.1, p=0.01, and p=0.001)

FIG. 37 is a line graph plotting the likelihood (relative probability) of cancer initiation relative to nulliparous (y-axis) against time of first pregnancy after menarche (years) on the x-axis for the indicated number of additional cell divisions during pregnancy (3 and 2).

DETAILED DESCRIPTION

Various aspects of the invention are described below.

I. Overview

A single full-term pregnancy in early adulthood decreases the risk of estrogen receptor (ER)-positive (+) postmenopausal breast cancer, the most common form of the disease. Age at first pregnancy is critical, as the protective effect decreases after the mid 20 s, and women aged >35 years at first birth have increased risk of both ER+ and ER− breast cancer. Parity-associated risk is also influenced by germline variants, as BRCA1 and BRCA2 mutation carriers do not experience the same decrease in risk reduction as does the general population. These human epidemiological data suggest that pregnancy induces long-lasting effects in the normal breast epithelium and that ER+ and ER− tumors might have a different cell of origin. The protective effect of parity is also observed in animal models, where its protective effect can be mimicked by hormonal factors in the absence of gestation.

The cellular and molecular mechanisms that underlie pregnancy and hormone-induced refractoriness to carcinogens are largely undefined. Several hypotheses have been proposed including the induction of differentiation, decreased susceptibility to carcinogens, a decrease in cell proliferation and in the number of mammary epithelial stem cells, an altered systemic environment due to a decrease in circulating growth hormone and other endocrine factors, and permanent molecular changes leading to alterations in cell fate. Almost all studies investigating pregnancy-induced changes and the breast cancer preventative effects of pregnancy have been conducted in rodent models and most of them have focused only on the mammary gland. Global gene expression profiling of mammary glands from virgin and parous rats identified changes in TGFβ and IGF signaling, and in the expression of extracellular matrix proteins.

Related studies conducted in humans also identified consistent differences in gene expression profiles between nulliparous and parous women (see Asztalos et al. (2010) Cancer Prev Res (Phila) 3, 301-311; Belitskaya-Levy et al. (2011) Cancer Prev Res (Phila) 4, 1457-1464; Russo et al. (2008) Cancer Epidemiol Biomarkers Prev 17, 51-66; and Russo et al. (2011) Int J Cancer; October 25; E-pub ahead of print). Because those studies used total mammary gland or mammary organoids, which are composed of multiple cell types the cellular origin of these gene expression differences remains unknown. Emerging data indicate that mammary epithelial progenitor or stem cells are the cell of origin of breast carcinomas. Studies assessing changes in mammary epithelial stem cells following pregnancy, however, have been conducted only in mice and thus far have been inconclusive. Thus, the effect of pregnancy on the number and functional properties of murine mammary epithelial progenitors is still elusive and it has not yet been analyzed in humans.

It is presently discovered that parity has a pronounced effect on CD44+ cells with progenitor features. As demonstrated in the present Examples, most of the differences in CD44+ cells between nulliparous and parous samples related to transcriptional repression and downregulation of genes and pathways important for stem cell function, many of which also play a role in tumorigenesis, including EGF, IGF, Hh, and TGFβ signaling. High circulating IGF-1 levels have been associated with increased risk of ER+ breast cancer, and germline polymorphism in members of the TGFβ signaling pathway have also been described to influence breast cancer susceptibility.

The present Examples also demonstrate that parity not only influences the risk of developing breast cancer, but potentially even the type of tumor and associated clinical outcome in breast cancer patients. Moreover, based on the genomic profiling and functional validation results in tissue explant cultures shown in the present Examples, the pathways that were identified as less active in parous women can be used for risk stratification and for chemoprevention in high-risk women, as their inhibition will mimic the cancer-reducing effects of parity.

The present Examples also demonstrate a significant decrease in the number of p27+ cells in breast tissues of parous women, which seems paradoxical as p27 (also known as CDKN1B/p27(kip1)) is a bona fide tumor suppressor and potent inhibitor of cell cycle progression. p27 has been shown to play an important role in stem cells, best characterized in the hematopoietic system, where loss of p27 increases the number of transit amplifying progenitors but not that of stem cells. In the mouse mammary gland, p27 deficiency leads to hypoplasia and impaired ductal branching and lobulo-alveolar differentiation, a phenotype consistent with a putative role in regulating the number and proliferation of mammary epithelial progenitors, although this has not been investigated.

While not intending to be bound by any one particular theory or mechanism of action, based on the data in the present Examples, it is thought that p27 regulates the proliferation and pool size of hormone-responsive breast epithelial progenitors; thus, the lower number of p27+ cells in parous women reflects a decrease in the number of quiescent progenitors with proliferative potential, which may contribute to their decrease in breast cancer risk. High p27 levels and quiescence are maintained in these cells by TGFβ signaling, as implied by the co-expression of pSmad2 with p27 and the increase in BrdU incorporation with concomitant decrease in p27 (Example 9).

It is also presently discovered that the frequency of p27+ cells was high in control nulliparous women and even higher in BRCA1 and BRCA2 mutation carriers even though these different groups of women are predisposed to different types of breast cancer (Example 2). Nulliparous women have increased risk of postmenopausal ER+ breast cancer, whereas BRCA1 mutation carriers most commonly have ER− basal-like tumors. However, recently published studies analyzing the potential cell-of-origin of BRCA1-associated breast cancer in animal models and in humans have found that even these basal-like tumors may initiate from luminal progenitors. The present Examples demonstrate increased frequency of hormone responsive p27+ cells in all high-risk women, supporting these hypotheses.

Thus, the number of p27+ breast epithelial progenitor (CD44+) cells in the normal breast and the activity of pathways that regulate the number of p27+ cells can be used as markers for predicting the risk of developing breast cancer (e.g., ER+ breast cancer or ER− breast cancer), as novel targets for cancer preventive and treatment strategies (e.g. therapeutic intervention), and for monitoring the efficacy of such preventive and treatment strategies. Furthermore, the pathways identified herein, e.g., a TGFβ pathway, can be exploited for breast cancer prevention, as they can be modulated to deplete p27+ cells with progenitor features and consequently decrease breast cancer risk.

II. Definitions

As used herein, the term “estrogen-receptor-positive (ER+) breast cancer” means a cancer wherein at least one cancer cell expresses the estrogen receptor. As used herein, the term “estrogen-receptor-negative (ER−) breast cancer” means a cancer wherein the cancer cells do not express the estrogen receptor.

As used herein, a “breast tissue sample” can include, but is not limited to, histological sections of normal breast tissue, e.g., healthy breast tissue, tumors or cancer cell-containing tissue, whole or soluble fractions of tissue or cell (e.g., cancer cell) lysates, cell subfractions (e.g., mitochondrial or nuclear subfractions), whole or soluble fractions of tissue or cell (e.g., cancer cell) subfraction lysates can be analyzed.

As used herein, a cell that is “positive” for a marker, such as, e.g., a CD44+, p27+, CD24+, or CD10+ cell, expresses the marker at the mRNA and/or protein level.

As used herein, breast “stromal cells” are breast cells other than epithelial cells.

As used herein, the term “subject” means any animal, including any vertebrate or mammal, and, in particular, a human, and can also be referred to, e.g., as an individual or patient. Typically, not necessarily, the subject is female. A subject in “need of such predicting” i.e., a subject in need of predicting the subject's risk of developing breast cancer, can be, e.g., a subject with a family history of breast cancer, a subject who has not been tested for and/or has not been diagnosed with breast cancer, a subject who wishes to know their risk of developing breast cancer, e.g., ER+ or ER− breast cancer, and/or a subject undergoing a routine health screen by, e.g., their attending physician, and/or a subject undergoing a therapy (e.g., raloxifen or tamoxifen) for the treatment and/or prevention of cancer (e.g., breast cancer).

As used herein, a subject (e.g., patient) having a characteristic (as described herein) that results in a “relatively elevated risk of developing breast cancer,” (e.g., ER+ or ER− breast cancer) has a greater risk of developing breast cancer than a subject not having that characteristic. Conversely, a subject having a characteristic (as described herein) that results in a “relatively reduced risk of developing breast cancer,” has a lesser risk of developing breast cancer than a subject not having that characteristic.

As used herein, a “parous” subject is a woman who has carried a pregnancy for at least 37 weeks of gestation, one or more times. As used herein, a “nulliparous” subject is a woman who has never carried a pregnancy for at least 37 weeks gestation.

As used herein, a “first control frequency” of a cell type (e.g., CD44+ or CD24+ cells) is the frequency of the cell type in a comparable sample from a patient or the average frequency in comparable samples from a plurality of patients known to be at low risk of developing breast cancer (e.g., parous women not expressing BRCA1 or BRCA2 mutations). “Comparable sample” typically means the same sample type (e.g., tumor biopsy or histological section from the same tissue (e.g. breast tissue). The first control frequency can also be a “predetermined reference frequency” (i.e., standard) to which the frequency of the cell type in a test sample is compared. As used herein, a “second control frequency” of a cell type (e.g., CD44+ or CD24+ cells) is the frequency of the cell type in a comparable sample from a patient or the average frequency in comparable samples from a plurality of patients known to be at high risk of developing breast cancer (e.g., nulliparous women).

As used herein, the “expression level” of a marker, such as, e.g., CD44, CD24, CD10, p27, Ki67, Sox17, Cox2, cAMP, EGFR, TGFBR, Cox2, Hh, and IGFR, etc. means the mRNA and/or protein expression level of the marker, or the measurable level of the marker in a sample (e.g., the level of cAMP can be detected by immunoassay), which can be determined by any suitable method known in the art, such as, but not limited to Northern blot, polymerase chain reaction (PCR), e.g., quantitative real-time, “QPCR”, Western blot, immunoassay (e.g., ELISA), immunohistochemistry, cell immunostaining and fluorescence activated cell sorting (FACS), etc.

As used herein, a “substantially altered” level of expression of a gene in a first cell (or first tissue) compared to a second cell (or second tissue) is an at least 2-fold (e.g., at least: 2-; 3-; 4-; 5-; 6-; 7-; 8-; 9-; 10-; 15-; 20-; 30-; 40-; 50-; 75-; 100-; 200-; 500-; 1,000-; 2000-; 5,000-; or 10,000-fold) altered level of expression of the gene. It is understood that the alteration can be an increase or a decrease.

As used herein, the term “selectively targets”, e.g., in the context of a specific cell type (e.g., CD44+, CD24− breast epithelial cells, p27+ breast epithelial cells, etc.) means the targeting agent (e.g., an inhibitor or agonist) mediates an effect on the specific target cell, but not on other cells. Thus, for example, an inhibitor that selectively targets CD44+ cells will mediate an effect (e.g. inhibition, e.g., of proliferation) on CD44+ cells, but not on CD44− cells. Such selective targeting can be achieved, e.g., by conjugating the inhibitor to an antibody that specifically binds to the target cell (e.g., an anti-CD44 antibody), as well as by other methods known in the art.

As used herein, “treating” or “treatment” of a state, disorder or condition includes: (1) preventing or delaying the appearance of clinical or sub-clinical symptoms of the state, disorder or condition developing in a mammal that may be afflicted with or predisposed to the state, disorder or condition but does not yet experience or display clinical or subclinical symptoms of the state, disorder or condition; and/or (2) inhibiting the state, disorder or condition, i.e., arresting, reducing or delaying the development of the disease or a relapse thereof (in case of maintenance treatment) or at least one clinical or sub-clinical symptom thereof; and/or (3) relieving the disease, i.e., causing regression of the state, disorder or condition or at least one of its clinical or sub-clinical symptoms; and/or (4) causing a decrease in the severity of one or more symptoms of the disease. The benefit to a subject to be treated is either statistically significant or at least perceptible to the patient or to the physician.

As used herein, the term “treating cancer” (e.g., treating an ER+ or ER− breast cancer) means causing a partial or complete decrease in the rate of growth of a tumor, and/or in the size of the tumor and/or in the rate of local or distant tumor metastasis in the presence of an inhibitor of the invention, and/or any decrease in tumor survival.

As used herein, the term “preventing a disease” (e.g., preventing ER+ or ER− breast cancer) in a subject means for example, to stop the development of one or more symptoms of a disease in a subject before they occur or are detectable, e.g., by the patient or the patient's doctor. Preferably, the disease (e.g., cancer) does not develop at all, i.e., no symptoms of the disease are detectable. However, it can also result in delaying or slowing of the development of one or more symptoms of the disease. Alternatively, or in addition, it can result in the decreasing of the severity of one or more subsequently developed symptoms.

As used herein, a “pathway that has decreased activity”, e.g., in breast epithelial cells (e.g., CD44+, CD24− breast epithelial cells)) of parous or nulliparous women means a pathway involving one or more genes or polypeptides mediating a function in the pathway that have reduced level of expression and/or activity. Non-limiting examples of such pathways are exemplified in Tables 10 and 11.

As used herein, the term “parity/nulliparity-related gene signature” means the known expression level of a group of two or more genes in breast epithelial cells of parous and nulliparous women (as disclosed herein). For example, the group of genes that were shown to be upregulated or downregulated in FIG. 28 , or a subgroup of the genes, are part of such parity/nulliparity-related gene signature. The genes shown in FIG. 28 are summarized in Table 18. Of course, the skilled artisan will appreciate that a parity/nulliparity-related gene signature can, but does not necessarily, include all of the genes shown in Table 18. Preferably, the signature includes 2 or more, 3 or more, 4 or more, 5 or more, 10 or more, 15 or more, 20 or more, 30 or more, 40 or more, 50 or more, or 100 or more of the genes shown in Table 18.

As used herein “combination therapy” means the treatment of a subject in need of treatment with a certain composition or drug in which the subject is treated or given one or more other compositions or drugs for the disease in conjunction with the first and/or in conjunction with one or more other therapies, such as, e.g., a cancer therapy such as chemotherapy, radiation therapy, and/or surgery. Such combination therapy can be sequential therapy wherein the patient is treated first with one treatment modality (e.g., drug or therapy), and then the other (e.g., drug or therapy), and so on, or all drugs and/or therapies can be administered simultaneously. In either case, these drugs and/or therapies are said to be “coadministered.” It is to be understood that “coadministered” does not necessarily mean that the drugs and/or therapies are administered in a combined form (i.e., they may be administered separately or together to the same or different sites at the same or different times).

The term “pharmaceutically acceptable derivative” as used herein means any pharmaceutically acceptable salt, solvate or prodrug, e.g., ester, of a compound of the invention, which upon administration to the recipient is capable of providing (directly or indirectly) a compound of the invention, or an active metabolite or residue thereof. Such derivatives are recognizable to those skilled in the art, without undue experimentation. Nevertheless, reference is made to the teaching of Burger's Medicinal Chemistry and Drug Discovery, 5th Edition, Vol 1: Principles and Practice, which is incorporated herein by reference to the extent of teaching such derivatives. Pharmaceutically acceptable derivatives include salts, solvates, esters, carbamates, and/or phosphate esters.

As used herein the terms “therapeutically effective” and “effective amount”, used interchangeably, applied to a dose or amount refer to a quantity of a composition, compound or pharmaceutical formulation that is sufficient to result in a desired activity upon administration to an animal in need thereof. Within the context of the present invention, the term “therapeutically effective” refers to that quantity of a composition, compound or pharmaceutical formulation that is sufficient to reduce or eliminate at least one symptom of a disease or condition specified herein, e.g., breast cancer such as ER+ or ER− breast cancer. When a combination of active ingredients is administered, the effective amount of the combination may or may not include amounts of each ingredient that would have been effective if administered individually. The dosage of the therapeutic formulation will vary, depending upon the nature of the disease or condition, the patient's medical history, the frequency of administration, the manner of administration, the clearance of the agent from the host, and the like. The initial dose may be larger, followed by smaller maintenance doses. The dose may be administered, e.g., weekly, biweekly, daily, semi-weekly, etc., to maintain an effective dosage level.

Therapeutically effective dosages can be determined stepwise by combinations of approaches such as (i) characterization of effective doses of the composition or compound in in vitro cell culture assays using tumor cell growth and/or survival as a readout followed by (ii) characterization in animal studies using tumor growth inhibition and/or animal survival as a readout, followed by (iii) characterization in human trials using enhanced tumor growth inhibition and/or enhanced cancer survival rates as a readout.

The term “nucleic acid hybridization” refers to the pairing of complementary strands of nucleic acids. The mechanism of pairing involves hydrogen bonding, which may be Watson-Crick, Hoogsteen or reversed Hoogsteen hydrogen bonding, between complementary nucleoside or nucleotide bases (nucleobases) of the strands of nucleic acids. For example, adenine and thymine are complementary nucleobases that pair through the formation of hydrogen bonds. Hybridization can occur under varying circumstances. Nucleic acid molecules are “hybridizable” to each other when at least one strand of one nucleic acid molecule can form hydrogen bonds with the complementary bases of another nucleic acid molecule under defined stringency conditions. Stringency of hybridization is determined, e.g., by (i) the temperature at which hybridization and/or washing is performed, and (ii) the ionic strength and (iii) concentration of denaturants such as formamide of the hybridization and washing solutions, as well as other parameters. Hybridization requires that the two strands contain substantially complementary sequences. Depending on the stringency of hybridization, however, some degree of mismatches may be tolerated. Under “low stringency” conditions, a greater percentage of mismatches are tolerable (i.e., will not prevent formation of an anti-parallel hybrid). See Molecular Biology of the Cell, Alberts et al., 3rd ed., New York and London: Garland Publ., 1994, Ch. 7.

Typically, hybridization of two strands at high stringency requires that the sequences exhibit a high degree of complementarity over an extended portion of their length. Examples of high stringency conditions include: hybridization to filter-bound DNA in 0.5 M NaHPO4, 7% SDS, 1 mM EDTA at 65° C., followed by washing in 0.1×SSC/0.1% SDS (where 1×SSC is 0.15 M NaCl, 0.15 M Na citrate) at 68° C. or for oligonucleotide (oligo) inhibitors washing in 6×SSC/0.5% sodium pyrophosphate at about 37° C. (for 14 nucleotide-long oligos), at about 48° C. (for about 17 nucleotide-long oligos), at about 55° C. (for 20 nucleotide-long oligos), and at about 60° C. (for 23 nucleotide-long oligos).

Conditions of intermediate or moderate stringency (such as, for example, an aqueous solution of 2×SSC at 65° C.; alternatively, for example, hybridization to filter-bound DNA in 0.5 M NaHPO₄, 7% SDS, 1 mM EDTA at 65° C. followed by washing in 0.2×SSC/0.1% SDS at 42° C.) and low stringency (such as, for example, an aqueous solution of 2×SSC at 55° C.), require correspondingly less overall complementarity for hybridization to occur between two sequences. Specific temperature and salt conditions for any given stringency hybridization reaction depend on the concentration of the target DNA or RNA molecule and length and base composition of the probe, and are normally determined empirically in preliminary experiments, which are routine (see Southern, J. Mol. Biol. 1975; 98:503; Sambrook et al., Molecular Cloning: A Laboratory Manual, 2nd ed., vol. 2, ch. 9.50, CSH Laboratory Press, 1989; Ausubel et al. (eds.), 1989, Current Protocols in Molecular Biology, Vol. I, Green Publishing Associates, Inc., and John Wiley & Sons, Inc., New York, at p. 2.10.3). An extensive guide to the hybridization of nucleic acids is found in, e.g., Tijssen (1993) Laboratory Techniques in Biochemistry and Molecular Biology—Hybridization with Nucleic Acid Probes part 1, chapt 2, “Overview of principles of hybridization and the strategy of nucleic acid probe assays,” Elsevier, N.Y. (“Tijssen”).

As used herein, the term “standard hybridization conditions” refers to hybridization conditions that allow hybridization of two nucleotide molecules having at least 50% sequence identity. According to a specific embodiment, hybridization conditions of higher stringency may be used to allow hybridization of only sequences having at least 75% sequence identity, at least 80% sequence identity, at least 90% sequence identity, at least 95% sequence identity, or at least 99% sequence identity.

As used herein, the phrase “under hybridization conditions” means under conditions that facilitate specific hybridization of a subset of capture oligonucleotides to complementary sequences present in the cDNA or cRNA. The terms “hybridizing specifically to” and “specific hybridization” and “selectively hybridize to,” as used herein refer to the binding, duplexing, or hybridizing of a nucleic acid molecule preferentially to a particular nucleotide sequence under at least moderately stringent conditions, and preferably, highly stringent conditions, as discussed above.

“Polypeptide” and “protein” are used interchangeably and mean any peptide-linked chain of amino acids, regardless of length or post-translational modification.

As used herein, the term “nucleic acid” or “oligonucleotide” refers to a deoxyribonucleotide or ribonucleotide in either single- or double-stranded form. The term al so encompasses nucleic-acid-like structures with synthetic backbones. DNA backbone analogues provided by the invention include phosphodiester, phosphorothioate, phosphorodithioate, methylphosphonate, phosphoramidate, alkyl phosphotriester, sulfamate, 3′-thioacetal, methylene(methylimino), 3′-N-carbamate, morpholino carbamate, and peptide nucleic acids (PNAs); see Oligonucleotides and Analogues, a Practical Approach, edited by F. Eckstein, IRL Press at Oxford University Press (1991); Antisense Strategies, Annals of the New York Academy of Sciences, Volume 600, Eds. Baserga and Denhardt (NYAS 1992); Milligan (1993) J. Med. Chem. 36:1923-1937; Antisense Research and Applications (1993, CRC Press). PNAs contain non-ionic backbones, such as N-(2-aminoethyl) glycine units. Phosphorothioate linkages are described in WO 97/03211; WO 96/39154; Mata (1997) Toxicol. Appl. Pharmacol. 144:189-197. Other synthetic backbones encompassed by the term include methyl-phosphonate linkages or alternating methylphosphonate and phosphodiester linkages (Strauss-Soukup (1997) Biochemistry 36:8692-8698), and benzylphosphonate linkages (Samstag (1996) Antisense Nucleic Acid Drug Dev 6:153-156). The term nucleic acid is used interchangeably with cDNA, cRNA, mRNA, oligonucleotide, probe and amplification product.

III. Cell Markers

In certain embodiments, it is desirable to detect the presence and/or expression level of one or more cell markers (e.g., estrogen receptor (ER), p27, CD24, CD44, CD10, Ki67, BRCA1, BRCA2, etc.) associated with breast epithelial cells and/or breast cancer (e.g., ER+ or ER− breast cancer). Moreover, the present document features methods in which the relative numbers of cells expressing one or more of these markers are determined. The nucleic acid and amino acid sequences for such markers are known and have been described, and the GenBank® Accession Nos. of exemplary nucleic acid and amino acid sequences for the human markers are provided in Table 1, below.

TABLE 1 Exemplary GenBank ® Accession Numbers Breast Cancer-Associated Markers Nucleic Acid Amino Acid GenBank ® SEQ Corresponding GenBank ® SEQ Gene Name Accession No. ID NO Polypeptide Name Accession No. ID NO CD24 BG327863 1 Sialoglycoprotein ACI46150.1 2 CD10 NM_007289.2 3 Neprilysin NP_009220.2 4 CD44 BC004372 5 CD44 AAB30429.1 6 P27/CDKN1B BC001971 7 CDKN1B CAG33680.1 8 Ki67 (MKI67) AU152107 9 KI67 antigen CAD99007.1 10 Homo sapiens NM_022454.3 11 transcription factor NP_071899 12 SRY (sex SOX-17 determining region Y)-box 17 (SOX17) Prostaglandin- NM_000963 13 prostaglandin G/H NP_000954 14 endoperoxide synthase 2 synthase 2 precursor (prostaglandin G/H synthase and cyclooxygenase) (PTGS2) Epidermal NM_005228 15 Epidermal growth NP_005219.2 19 Growth Factor NM_201282 16 factor receptor NP_958439.1 20 Receptor P NM_201283.1 17 NP_958440.1 21 (EGFR) NM_201284 18 NP_958441.1 22 sonic hedgehog NM_000193 23 Sonic hedgehog NP_000184 24 protein (SHH) protein insulin-like NM_000875 25 Insulin like NP000866 26 growth factor 1 Growth factor receptor receptor (IGF1R) transforming NM_004612 27 Transforming NP_004603 29 growth factor, NM_001130916 28 Growth factor NP_001124388 30 beta receptor 1 receptor beta (TGFBR1) receptor estrogen NM_000125.3 31 Estrogen Receptor NP_000116 35 receptor 1 NM_001122740.1 32 I NP_001116212 36 (ESR1) NM_001122741.1 33 NP_001116213 37 NM_001122742.1 34 NP_001116214 38 breast cancer NM_007294.3 39 breast cancer type NP_009225 44 type 1 NM_007300.3 40 1 susceptibility NP_009231.2 45 susceptibility NM_007297.3 41 protein (BRCA1) NP_009228.2 46 protein NM_007298.3 42 NP_009229.2 47 (BRCA1) NM_007299.3 43 NP_009230.2 48 Homo sapiens NM_000059 49 breast cancer type NP_000050 50 breast cancer 2, 2 susceptibility early onset protein (BRCA2) (BRCA2), Androgen NM_000044 51 Androgen NP_000035 53 Receptor (AR) NM_001011645 52 Receptor (AR) NP_001011645 54

In certain embodiments, it is desirable to determine (e.g., assay, measure, approximate) the level (e.g., expression or activity), e.g., one of the above-identified markers. The expression level of such markers may be determined according to any suitable method known in the art. A non-limiting example of such a method includes real-time PCR (RT-PCR), e.g., quantitative RT-PCR (QPCR), which measures the expression level of the mRNA encoding the polypeptide. Real-time PCR evaluates the level of PCR product accumulation during amplification. RNA (or total genomic DNA for detection of germline mutations) is isolated from a sample. RT-PCR can be performed, for example, using a Perkin Elmer/Applied Biosystems (Foster City, Calif.) 7700 Prism instrument. Matching primers and fluorescent probes can be designed for genes of interest using, based on the genes' nucleic acid sequences (e.g., as described above), for example, the primer express program provided by Perkin Elmer/Applied Biosystems (Foster City, Calif.). Optimal concentrations of primers and probes can be initially determined by those of ordinary skill in the art, and control (for example, beta-actin) primers and probes may be obtained commercially from, for example, Perkin Elmer/Applied Biosystems (Foster City, Calif.).

To quantitate the amount of the specific nucleic acid of interest in a sample, a standard curve is generated using a control. Standard curves may be generated using the Ct values determined in the real-time PCR, which are related to the initial concentration of the nucleic acid of interest used in the assay. Standard dilutions ranging from 10-10⁶ copies of the gene of interest are generally sufficient. In addition, a standard curve is generated for the control sequence. This permits standardization of initial content of the nucleic acid of interest in a tissue sample to the amount of control for comparison purposes. Methods of QPCR using TaqMan probes are well known in the art. Detailed protocols for QPCR are provided, for example, for RNA in: Gibson et al., 1996, Genome Res., 10:995-1001; and for DNA in: Heid et al., 1996, Genome Res., 10:986-994; and in Innis et al. (1990) Academic Press, Inc. N.Y.

Expression of mRNA, as well as expression of peptides and other biological factors can also be determined using microarray, methods for which are well known in the art [see, e.g., Watson et al. Curr Opin Biotechnol (1998) 9: 609-14; “DNA microarray technology: Devices, Systems, and Applications” Annual Review of Biomedical Engineering; Vol. 4: 129-153 (2002); Chehab et al. (1989) “Detection of specific DNA sequences by fluorescence amplification: a color complementation assay” Proc. Natl. Acad. Sci. USA, 86: 9178-9182; Lockhart et al. (1996) “Expression monitoring by hybridization to high-density oligonucleotide arrays” Nature Biotechnology, 14: 1675-1680; and M. Schena et al. (1996) “Parallel human genome analysis: Microarray-based expression monitoring of 1000 genes” Proc. Natl. Acad. Sci. USA, 93:10614-10619; Peptide Microarrays Methods and Protocols; Methods in Molecular Biology; Volume 570, 2009, Humana Press; and Small Molecule Microarrays Methods and Protocols; Series: Methods in Molecular Biology, Vol. 669, Uttamchandani, Mahesh; Yao, Shao Q. (Eds.) 2010, 2010, Humana Press]. For example, mRNA expression profiling can be performed to identify differentially expressed genes, wherein the raw intensities determined by microarray are log₂-transformed and quantile normalized and gene set enrichment analysis (GSEA) is performed according, e.g., to Subramanian et al. (2005) Proc Natl Acad Sci USA 102:15545-15550).

Other suitable amplification methods include, but are not limited to ligase chain reaction (LCR) (see Wu and Wallace (1989) Genomics 4:560, Landegren et al. (1988) Science 241:1077, and Barringer et al. (1990) Gene 89:117), transcription amplification (Kwoh et al. (1989) Proc. Natl. Acad. Sci. USA 86:1173), self-sustained sequence replication (Guatelli et al. (1990) Proc. Nat. Acad. Sci. USA 87:1874), dot PCR, and linker adapter PCR, etc. In another embodiment, DNA sequencing may be used to determine the presence of ER in a genome. Methods for DNA sequencing are known to those of skill in the art.

Other methods for detecting gene expression (e.g., mRNA levels) include Serial Analysis of Gene Expression applied to high-throughput sequencing (SAGEseq), as described in the present Examples and in Wu Z J et al. Genome Res. 2010 December; 20(12):1730-9. 2.

For the detection of germline mutations (e.g., in BRCA1, BRCA2), Southern blotting can also be used. Methods for Southern blotting are known to those of skill in the art (see, e.g., Current Protocols in Molecular Biology, Chapter 19, Ausubel, et al., Eds., Greene Publishing and Wiley-Interscience, New York, 1995, or Sambrook et al., Molecular Cloning: A Laboratory Manual, 2d Ed. vol. 1-3, Cold Spring Harbor Press, N Y, 1989). In such an assay, the genomic DNA (typically fragmented and separated on an electrophoretic gel) is hybridized to a probe specific for the target region. Comparison of the intensity of the hybridization signal from the probe for the target region with control probe signal from analysis of normal genomic DNA (e.g., genomic DNA from the same or related cell, tissue, organ, etc.) provides an estimate of the relative copy number of the target nucleic acid. Arrays of nucleic probes can also be employed to detect single or multiple germline or somatic mutations by methods known in the art.

Other examples of suitable methods for detecting expression levels of the cell markers described herein include, e.g., Western blot, ELISA and/or immunohistochemistry, which can be used to measure protein expression level. Such methods are well known in the art.

The frequency of cells that are specific for one or more particular markers (e.g., the frequency of CD44+ or CD24+ breast epithelial cells) can be detected according to any suitable method known in the art. For example, flow cytometry is widely used for analyzing the expression of cell surface and intracellular molecules (on a per cell basis), characterizing and defining different cell types in heterogeneous populations, assessing the purity of isolated subpopulations, and analyzing cell size and volume. This technique is predominantly used to measure fluorescence intensity produced by fluorescent-labeled antibodies or ligands that bind to specific cell-associated molecules, and is described in detail in, e.g., Holmes, K. et al. “Preparation of Cells and Reagents for Flow Cytometry” Current Protocols in Immunology, Unit 5.3.

Non-limiting examples of primary antibodies that may be used to identify the expression of certain markers by one or more assays, e.g., by flow cytometry, immunohistochemistry (IHC), and/or Western blot are listed in Table 2, below:

TABLE 2 Exemplary Cell Marker Primary Antibodies Application (e.g., Cell Western blot, flow Commercial Marker Primary Antibody cytometry, IHC) Source CD24 clone SN3b IHC Neomarkers CD24 clone ML5 FACS Biolegend CD10 56C6 clone IHC Dako CD10 Clone HI10a FACS Biolegend CD44 clone 156-3C11 IHC Neomarkers CD44 Clone 515 FACS BD P27 clone 57/Kip1/p27 IHC Bd Biosciences Ki67 N/A IHC Abcam Sox17 clone 245013 IHC R&D Systems Cox2 clone CX229 IHC Cayman Chemical pEGFR 53A5 (Tyr1173) IHC Cell Signaling Technology Shh Cat# 06-1106 WB, IHC Millipore IGF-1R Clone 24-31 IHC (P) Imgenex pTGFBR Phospho S165 ICC/IF Abcam ER Estrogen Receptor IHC Thermo Scientific (clone SP1) AR Androgen receptor WB/IHC-P/IF/IC/F Cell Signaling (clone D6F11, Technology #5153) BRCA1 MS110 clone IF/IP/WB Calbiochem BRCA2 Cst#CA1033 WB/IP/IHC(P) Millipore Abbreviations: WB: Western blotting; IHC: Immunohistochemistry; IHC-P: immunohistochemistry-paraffin; ICC: immunocytochemistry; IF: immunofluorescence; F: flow cytometry

IV. Genes and Pathways Differentially Regulated by Parity Status

In certain embodiments, it is desirable to decrease (e.g., inhibit) the expression and/or activity of genes and/or polypeptides encoded by those genes that are discovered herein to be upregulated in breast epithelial cells of nulliparous women relative to parous women. For example, one or more of the genes that are upregulated in CD44+, CD24+, CD10+ and stromal breast epithelial cells of nulliparous women, in Tables 4, 5, 6 and 7, respectively, can be targeted with an inhibitor as described herein in order to treat or prevent breast cancer (e.g., ER+ or ER− breast cancer). Further, for example, one or more of the genes that are upregulated in CD44+ breast epithelial cells of BRCA1 and/or BRCA2 mutation carriers compared to control (normal) breast epithelial cells), as shown, e.g., in Tables 8 and 9 can be targeted with an inhibitor as described herein in order to treat or prevent breast cancer (e.g., ER+ or ER− breast cancer). By way of non-limiting example, asp27 expression is higher in BRCA1 mutation carriers and in BRCA2 mutation carriers compared to control (non-mutation carriers, normal cells), and is an exemplary target for an inhibitor as discussed above.

In other embodiments, it is desirable to increase the expression and/or activity of genes and/or polypeptides encoded by those genes that are discovered herein to be upregulated in breast epithelial cells of parous women relative to nulliparous women. For example, one or more of the genes that are upregulated in CD44+, CD24+, CD10+ and stromal breast epithelial cells of parous women, in Tables 4, 5, 6 and 7, respectively, can be targeted with an agonist as described herein in order to treat or prevent breast cancer (e.g., ER+ or ER− breast cancer). Further, for example, one or more of the genes that are downregulated in CD44+ breast epithelial cells of BRCA1 and/or BRCA2 mutation carriers compared to control (normal) breast epithelial cells), as shown, e.g., in Tables 8 and 9, can be targeted with an agonist as described herein in order to treat or prevent breast cancer (e.g., ER+ or ER− breast cancer).

In certain embodiments, methods for treating breast cancer (e.g., ER+ or ER− breast cancer) involve targeting (e.g., inhibiting) one or more pathways that have increased activity in breast epithelial cells (e.g., CD44+, CD24− breast epithelial cells) of nulliparous women compared to the activity in the breast epithelial cells of parous women (such pathways are also referred to herein as “pathways active in nulliparous (NP) breast epithelial cells”). The identification of such pathways is described in detail in Example 3, below, and the pathways are listed in Tables 10 and 11, below. In a specific embodiment, the pathway is a member selected from the group consisting of cytoskeleton remodeling, chemokine, androgen signaling, cell adhesion, and Wnt signaling. In another embodiment, the pathway includes a mediator molecule selected from the group consisting of cyclic AMP (cAmp) (Signal transduction cAMP signaling pathway), EGFR (e.g., Development EGFR signaling via small GTPases pathway, EGFR signaling pathway), Cox2 (e.g., Role and regulation of Prostaglandin E2 in gastric cancer pathway, Hh (e.g., hedgehog signaling pathways), and IGFR (IGFR-IGF signaling pathways).

In other embodiments, methods for treating breast cancer involve targeting (e.g., administering an agonist of) one or more pathways that have decreased activity in breast epithelial cells (e.g., CD44+, CD24− breast epithelial cells) of nulliparous women compared to the breast epithelial cells of parous women (i.e., pathways that have increased activity in breast epithelial cells of parous women, which also referred to herein as “pathways active in parous (P) breast epithelial cells). Such pathways are identified in Example 3 and Tables 10 and 12.

Exemplary pathways are pathways active in nulliparous CD44+, CD24− breast epithelial cells, as shown in Table 11, although pathways active in other nulliparous breast epithelial cells types (e.g., CD24+, CD10+ and/or stromal breast epithelial cells) are also encompassed herein, and include, but are not limited to, Cytoskeleton remodeling_Role of PKA in cytoskeleton reorganisation, Development_MAG-dependent inhibition of neurite outgrowth, Role of DNA methylation in progression of multiple myeloma, Cell adhesion_Histamine H1 receptor signaling in the interruption of cell barrier integrity, Stem cells_Response to hypoxia in glioblastoma stem cells, Development_WNT signaling pathway. Part 2, Development_Slit-Robo signaling, Cytoskeleton remodeling_Fibronectin-binding integrins in cell motility, Oxidative phosphorylation, etc. The genes and the polypeptides encoded by those genes that mediate one or more functions in these pathways are known in the art and can be determined using, e.g., Metaminer software (GeneGo). Thus, the following genes are provided as non-limiting examples of genes involved in the pathways active in nulliparous CD44+, CD24− breast epithelial cells.

For example, genes involved in metabolic pathways active in nulliparous CD44+, CD24− breast epithelial cells (e.g., the pathways: Transcription_Transcription regulation of amino acid metabolism, Regulation of lipid metabolism_Stimulation of Arachidonic acid production by ACM receptors, Ubiquinone metabolism, and Mitochondrial ketone bodies biosynthesis and metabolism), include, but are not limited to, HSD17B11 (GenBank Accession No. BC014327, CA775960), HSD17B12 (GenBank Accession No. AF078850), and HSD17B14 (GenBank Accession No. AF126781), which are involved in regulation of lipid metabolism pathways.

Genes involved in androgen signaling pathways active in nulliparous CD44+, CD24− breast epithelial cells (e.g., the pathways: “Putative role of Estrogen receptor and Androgen receptor signaling in progression of lung cancer”, “Androgen signaling in HCC” (see Tables 10 and 11)) include, but are not limited to, PSA (KLK3) (GenBank Accession Nos. AC011523, BC005307), which are involved in the androgen signaling.

Genes involved in developmental and thyroid signaling pathways active in nulliparous CD44+, CD24− breast epithelial cells (e.g., the pathways: Development_Glucocorticoid receptor signaling, Development_Hedgehog and PTH signaling pathways in bone and cartilage development) include, but are not limited to, NCOR1 (GenBank Accession No. AC002553), NCOR2 (GenBank Accession No. AB209089, AC073916), NCOA4 (GenBank Accession No. AL162047), and NCOA7 (GenBank Accession No. AJ420542).

Genes involved in Wnt signaling pathways active in nulliparous CD44+, CD24− breast epithelial cells (e.g., the pathways: Development_WNT signaling pathway, Cytoskeleton remodeling_TGF, WNT and cytoskeletal remodeling, Stem cells_WNT/Beta-catenin and NOTCH in induction of osteogenesis) include, but are not limited to, SFRP2 (GenBank Accession No. AA449032, AF311912), SFRP4 (GenBank Accession No. AC018634, BT019679), VEGFA (GenBank Accession Nos. AF024710, BF700556), HIF1A (GenBank Accession Nos. BC012527, CN264320), NOTCH1 (GenBank Accession Nos. AB209873, AF308602, AL592301), FN1 (GenBank Accession Nos AI033037, AJ535086).

Genes involved in chemokine pathways active in nulliparous CD44+, CD24− breast epithelial cells (e.g., the pathways: Cell adhesion_Chemokines and adhesion, Cell adhesion_Alpha-4 integrins in cell migration and adhesion, Cell adhesion_Plasmin signaling, Cell adhesion_ECM remodeling, Cell adhesion_Role of tetraspanins in the integrin-mediated cell adhesion) include, but are not limited to, ITGA4 (GenBank Accession No., AC020595) (ITGB1 (GenBank Accession No., A1261443), and TSPAN6 (GenBank Accession Nos. AF043906, BC012389).

Genes involved in cytoskeleton remodeling pathways active in nulliparous CD44+, CD24− breast epithelial cells (e.g., the pathways: Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases, Cytoskeleton remodeling_Fibronectin-binding integrins in cell motility, Cytoskeleton remodeling_Reverse signaling by ephrin B, Cytoskeleton remodeling_Role of PKA in cytoskeleton reorganisation) include, but are not limited to, RhoA (GenBank Accession Nos. AK130066, BC000946), RAC1 (GenBank Accession No. AC009412), CDC42 (GenBank Accession No., NM_001039802), and EPHB4 (GenBank Accession Nos. AY056048, BC052804).

The pathways for DNA repair, PI3K/AKT signaling, and apoptosis have been demonstrated herein to be active in parous CD44+, CD24− breast epithelial cells. Other non-limiting examples of pathways active in parous breast epithelial cells include, e.g., TTP metabolism, Resistance of pancreatic cancer cells to death receptor signaling, Transcription_Assembly of RNA Polymerase II preinitiation complex on TATA-less promoters, Development_PIP3 signaling in cardiac myocytes, HCV-dependent regulation of RNA polymerases leading to HCC, Stem cells_H3K9 demethylases in pluripotency maintenance of stem cells, Inhibition of apoptosis in gastric cancer, Cell cycle_Start of DNA replication in early S phase, Apoptosis and survival_Caspase cascade, Immune response_BCR pathway, Immune response_ICOS pathway in T-helper cell, Cell cycle_The metaphase checkpoint, Inhibitory action of Lipoxins on neutrophil migration, Cytoskeleton remodeling_Alpha-1A adrenergic receptor-dependent inhibition of PI3K, DNA damage_NHEJ mechanisms of DSBs repair, Regulation of metabolism_Triiodothyronine and Thyroxine signaling, Cell cycle_Chromosome condensation in prometaphase, Development_IGF-1 receptor signaling, dCTP/dUTP metabolism, dGTP metabolism, Inhibition of RUNX3 signaling in gastric cancer, Apoptosis and survival_Beta-2 adrenergic receptor anti-apoptotic action, Signal transduction_Activin A signaling regulation, Stem cells_Fetal brown fat cell differentiation, Immune response_CXCR4 signaling via second messenger, dATP/dITP metabolism, Signal transduction_PTEN pathway, Microsatellite instability in gastric cancer, Inhibition of TGF-beta signaling in gastric cancer, Immune response_Regulation of T cell function by CTLA-4, DNA damage_DNA-damage-induced responses, etc. (see Tables 10 and 12). The genes and proteins encoded by those genes that mediate functions in these pathways are well known in the art. Thus, the skilled artisan will know which specific genes and/or polypeptides to target (e.g., with an agonist) as described herein (e.g., for the treatment or prevention of breast cancer (e.g., ER+ or ER− breast cancer)).

By way of example, genes involved in apoptosis pathways active in parous CD44+, CD24− breast epithelial cells (e.g., the pathways, Apoptosis and survival_FAS signaling cascades, Apoptosis and survival_Caspase cascade, Apoptosis and survival HTR1A signaling, Apoptosis and survival_Beta-2 adrenergic receptor anti-apoptotic action, Apoptosis and survival_Granzyme A signaling, Apoptosis and survival_Cytoplasmic/mitochondrial transport of pro-apoptotic proteins Bid, Bmf and Bim) upregulated in parous breast epithelial cells included, but are not limited to, BCL2L11 (GenBank Accession Nos. AC096670, AI268146, AK290377, AY428962), TNFRSF4 (GenBank Accession Nos. AW290885, BC105070), BMPR2 (GenBank Accession Nos. AC009960, BC035097), CASP8 (GenBank Accession Nos. BF439983, AC007256, AF422927), and PP2A (GenBank Accession Nos. AL158151, CD630703, DA052599, X73478).

Genes involve in PI3K/AKT signaling pathways active in parous CD44+, CD24− breast epithelial cells (e.g., the pathways, Cytoskeleton remodeling_Alpha-1A adrenergic receptor-dependent inhibition of PI3K, Signal transduction_AKT signaling, PI3K signaling in gastric cancer) that are upregulated in parous breast epithelial cells included, but are not limited to, PIK3CG (GenBank Accession No. X83368), p85 (GenBank Accession No. AC016564, BC094795, CA427864, CT003423), ILK (GenBank Accession No. BC001554, CB113885, U40282), PDPK1 (GenBank Accession No. AC093525, AC141586, BC012103).

Genes involved in tumor suppressor pathways active in parous breast epithelial cells (e.g., the pathways: Apoptosis and survival_Cytoplasmic/mitochondrial transport of pro-apoptotic proteins Bid, Bmf and Bim, Apoptosis and survival_Caspase cascade, Cytoskeleton remodeling_Alpha-1A adrenergic receptor-dependent inhibition of PI3K, Cell cycle_The metaphase checkpoint) include, but are not limited to, Hakai/CBLL1 (GenBank Accession Nos. AC002467, AK026762, AK293352), CASP8 (GenBank Accession No. BF439983), SCRIB (GenBank Accession No. A1469403), and LLGL2 (GenBank Accession Nos. AC100787, BC031842).

The skilled artisan will appreciate that the foregoing are non-limiting examples of pathways, as well as genes and polypeptides mediating functions in those pathways, that can be targeted (e.g., by an inhibitor or agonist) for the treatment of breast cancer, and other targets, such as those set forth in Tables 10, 11, and 12, below, are also encompassed by the present invention.

V. Inhibitors and Agonists

Inhibitors and agonists may be used to treat or prevent breast cancer in a subject, as described herein. One of skill in the art will appreciate that the design of such inhibitors and agonists will depend on the specific pathway (e.g., metabolic pathways androgen signaling pathways, tumor suppression, etc., as described above) being targeted. The skilled artisan will understand how to design such inhibitors and agonists, based on methods well known in the art.

The following are thus provided as non-limiting examples (e.g., antisense nucleic acids, RNAi, ribozymes, triple helix forming oligonucleotides (TFOs), antibodies (including, but not limited to intrabodies), aptamers, and other small molecules), and other inhibitors that target pathways (e.g., inhibit expression and/or activity of specific genes and/or polypeptides encoded by those genes that mediate a function in the pathway) that are active in breast epithelial cells of nulliparous women, and agonists that target pathways (e.g., increase expression and/or activity of specific genes and/or polypeptides that mediate a function in the pathway) that are active in parous women, are also encompassed by the present disclosure.

Antisense Nucleic Acids

Antisense oligonucleotides can be used to inhibit the expression of a target polypeptide of the invention (e.g., HSD17B11, HSD17B12, HSD17B14, etc.). Antisense oligonucleotides typically are about 5 nucleotides to about 30 nucleotides in length, about 10 to about 25 nucleotides in length, or about 20 to about 25 nucleotides in length. For a general discussion of antisense technology, see, e.g., Antisense DNA and RNA, (Cold Spring Harbor Laboratory, D. Melton, ed., 1988).

Appropriate chemical modifications of the inhibitors are made to ensure stability of the antisense oligonucleotide, as described below. Changes in the nucleotide sequence and/or in the length of the antisense oligonucleotide can be made to ensure maximum efficiency and thermodynamic stability of the inhibitor. Such sequence and/or length modifications are readily determined by one of ordinary skill in the art.

The antisense oligonucleotides can be DNA or RNA or chimeric mixtures, or derivatives or modified versions thereof, and can be single-stranded or double-stranded. Thus, for example, in the antisense oligonucleotides set forth in herein, when a sequence includes thymidine residues, one or more of the thymidine residues may be replaced by uracil residues and, conversely, when a sequence includes uracil residues, one or more of the uracil residues may be replaced by thymidine residues.

Antisense oligonucleotides comprise sequences complementary to at least a portion of the corresponding target polypeptide. However, 100% sequence complementarity is not required so long as formation of a stable duplex (for single stranded antisense oligonucleotides) or triplex (for double stranded antisense oligonucleotides) can be achieved. The ability to hybridize will depend on both the degree of complementarity and the length of the antisense oligonucleotides. Generally, the longer the antisense oligonucleotide, the more base mismatches with the corresponding nucleic acid target can be tolerated. One skilled in the art can ascertain a tolerable degree of mismatch by use of standard procedures to determine the melting point of the hybridized complex.

Antisense nucleic acid molecules can be encoded by a recombinant gene for expression in a cell (see, e.g., U.S. Pat. Nos. 5,814,500 and 5,811,234), or alternatively they can be prepared synthetically (see, e.g., U.S. Pat. No. 5,780,607).

The antisense oligonucleotides can be modified at the base moiety, sugar moiety, or phosphate backbone, or a combination thereof. In one embodiment, the antisense oligonucleotide comprises at least one modified sugar moiety, e.g., a sugar moiety such as arabinose, 2-fluoroarabinose, xylulose, and hexose.

In another embodiment, the antisense oligonucleotide comprises at least one modified phosphate backbone such as a phosphorothioate, a phosphorodithioate, a phosphoramidothioate, a phosphoramidate, a phosphorodiamidate, a methylphosphonate, an alkyl phosphotriester, and a formacetal or analog thereof. Examples include, without limitation, phosphorothioate antisense oligonucleotides (e.g., an antisense oligonucleotide phosphothioate modified at 3′ and 5′ ends to increase its stability) and chimeras between methylphosphonate and phosphodiester oligonucleotides. These oligonucleotides provide good in vivo activity due to solubility, nuclease resistance, good cellular uptake, ability to activate RNase H, and high sequence selectivity.

Other examples of synthetic antisense oligonucleotides include oligonucleotides that contain phosphorothioates, phosphotriesters, methyl phosphonates, short chain alkyl, or cycloalkyl intersugar linkages or short chain heteroatomic or heterocyclic intersugar linkages. Most preferred are those with CH2-NH—O—CH2, CH2-N(CH3)-O—CH2, CH2-O—N(CH3)-CH2, CH2-N(CH3)-N(CH3)-CH2 and O—N(CH3)-CH2-CH2 backbones (where phosphodiester is O—PO2-O—CH2). U.S. Pat. No. 5,677,437 describes heteroaromatic oligonucleoside linkages. Nitrogen linkers or groups containing nitrogen can also be used to prepare oligonucleotide mimics (U.S. Pat. Nos. 5,792,844 and 5,783,682). U.S. Pat. No. 5,637,684 describes phosphoramidate and phosphorothioamidate oligomeric compounds.

In other embodiments, such as the peptide-nucleic acid (PNA) backbone, the phosphodiester backbone of the oligonucleotide may be replaced with a polyamide backbone, the bases being bound directly or indirectly to the aza nitrogen atoms of the polyamide backbone (Nielsen et al., Science 1991; 254:1497). Other synthetic oligonucleotides may contain substituted sugar moieties comprising one of the following at the 2′ position: OH, SH, SCH3, F, OCN, O(CH2)nNH2 or O(CH2)nCH3 where n is from 1 to about 10; C1 to C10 lower alkyl, substituted lower alkyl, alkaryl or aralkyl; Cl; Br; CN; CF3; OCF3; O—; S—, or N-alkyl; O-, S-, or N-alkenyl; SOCH3; SO2CH3; ONO2; NO2; N3; NH2; heterocycloalkyl; heterocycloalkaryl; aminoalkylamino; polyalkylamino; substituted sialyl; a fluorescein moiety; an RNA cleaving group; a reporter group; an intercalator; a group for improving the pharmacokinetic properties of an oligonucleotide; or a group for improving the pharmacodynamic properties of an oligonucleotide, and other substituents having similar properties.

Oligonucleotides may also have sugar mimetics such as cyclobutyls or other carbocyclics in place of the pentofuranosyl group. Nucleotide units having nucleosides other than adenosine, cytidine, guanosine, thymidine and uridine may be used, such as inosine. In other embodiments, locked nucleic acids (LNA) can be used (reviewed in, e.g., Jepsen and Wengel, Curr. Opin. Drug Discov. Devel. 2004; 7:188-194; Crinelli et al., Curr. Drug Targets 2004; 5:745-752). LNA are nucleic acid analog(s) with a 2′-O, 4′-C methylene bridge. This bridge restricts the flexibility of the ribofuranose ring and locks the structure into a rigid C3-endo conformation, conferring enhanced hybridization performance and exceptional biostability. LNA allows the use of very short oligonucleotides (less than 10 bp) for efficient hybridization in vivo.

In one embodiment, an antisense oligonucleotide can comprise at least one modified base moiety such as a group including but not limited to 5-fluorouracil, 5-bromouracil, 5-chlorouracil, 5-iodouracil, hypoxanthine, xanthine, 4-acetylcytosine, 5-(carboxyhydroxylmethyl) uracil, 5-carboxymethylaminomethyl-2-thiouridine, 5-carboxymethylaminomethyluracil, dihydrouracil, beta-D-galactosylqueuosine, inosine, N6-isopentenyladenine, 1-methylguanine, 1-methylinosine, 2,2-dimethylguanine, 2-methyladenine, 2-methylguanine, 3-methylcytosine, 5-methylcytosine, N6-adenine, 7-methylguanine, 5-methylaminomethyluracil, 5-methoxyaminomethyl-2-thiouracil, beta-D-mannosylqueuosine, 5-methoxycarboxymethyluracil, 5-methoxyuracil, 2-methylthio-N6-isopentenyladenine, uracil-5-oxyacetic acid (v), pseudouracil, queuosine, 2-thiocytosine, 5-methyl-2-thiouracil, 2-thiouracil, 4-thiouracil, 5-methyluracil, uracil-5-oxyacetic acid methylester, uracil-5-oxyacetic acid (v), 5-methyl-2-thiouracil, 3-(3-amino-3-N-2-carboxypropyl) uracil, (acp3)w, and 2,6-diaminopurine.

In another embodiment, the antisense oligonucleotide can include α-anomeric oligonucleotides. An α-anomeric oligonucleotide forms specific double-stranded hybrids with complementary RNA in which, contrary to the usual β-units, the strands run parallel to each other (Gautier et al., Nucl. Acids Res. 1987; 15:6625-6641).

Oligonucleotides may have morpholino backbone structures (U.S. Pat. No. 5,034,506). Thus, in yet another embodiment, the antisense oligonucleotide can be a morpholino antisense oligonucleotide (i.e., an oligonucleotide in which the bases are linked to 6-membered morpholine rings, which are connected to other morpholine-linked bases via non-ionic phosphorodiamidate intersubunit linkages). Morpholino oligonucleotides are highly resistant to nucleases and have good targeting predictability, high in-cell efficacy and high sequence specificity (U.S. Pat. No. 5,034,506; Summerton, Biochim. Biophys. Acta 1999; 1489:141-158; Summerton and Weller, Antisense Nucleic Acid Drug Dev. 1997; 7:187-195; Arora et al., J. Pharmacol. Exp. Ther. 2000; 292:921-928; Qin et al., Antisense Nucleic Acid Drug Dev. 2000; 10:11-16; Heasman et al., Dev. Biol. 2000; 222:124-134; Nasevicius and Ekker, Nat. Genet. 2000; 26:216-220).

Antisense oligonucleotides may be chemically synthesized, for example using appropriately protected ribonucleoside phosphoramidites and a conventional DNA/RNA synthesizer. Antisense nucleic acid oligonucleotides can also be produced intracellularly by transcription from an exogenous sequence. For example, a vector can be introduced in vivo such that it is taken up by a cell within which the vector or a portion thereof is transcribed to produce an antisense RNA. Such a vector can remain episomal or become chromosomally integrated, so long as it can be transcribed to produce the desired antisense RNA. Such vectors can be constructed by recombinant DNA technology methods standard in the art. Vectors can be plasmid, viral, or others known in the art, used for replication and expression in mammalian cells. In another embodiment, “naked” antisense nucleic acids can be delivered to adherent cells via “scrape delivery”, whereby the antisense oligonucleotide is added to a culture of adherent cells in a culture vessel, the cells are scraped from the walls of the culture vessel, and the scraped cells are transferred to another plate where they are allowed to re-adhere. Scraping the cells from the culture vessel walls serves to pull adhesion plaques from the cell membrane, generating small holes that allow the antisense oligonucleotides to enter the cytosol.

RNAi

Reversible short inhibition of a target polypeptide (e.g., Gfpt1, RPIA, RPE, etc.) of the invention may also be useful. Such inhibition can be achieved by use of siRNAs. RNA interference (RNAi) technology prevents the expression of genes by using small RNA molecules such as small interfering RNAs (siRNAs). This technology in turn takes advantage of the fact that RNAi is a natural biological mechanism for silencing genes in most cells of many living organisms, from plants to insects to mammals (McManus et al., Nature Reviews Genetics, 2002, 3(10) p. 737). RNAi prevents a gene from producing a functional protein by ensuring that the molecule intermediate, the messenger RNA copy of the gene is destroyed siRNAs can be used in a naked form and incorporated in a vector, as described below.

RNA interference (RNAi) is a process of sequence-specific post-transcriptional gene silencing by which double stranded RNA (dsRNA) homologous to a target locus can specifically inactivate gene function in plants, fungi, invertebrates, and vertebrates, including mammals (Hammond et al., Nature Genet. 2001; 2:110-119; Sharp, Genes Dev. 1999; 13:139-141). This dsRNA-induced gene silencing is mediated by short double-stranded small interfering RNAs (siRNAs) generated from longer dsRNAs by ribonuclease III cleavage (Bernstein et al., Nature 2001; 409:363-366 and Elbashir et al., Genes Dev. 2001; 15:188-200). RNAi-mediated gene silencing is thought to occur via sequence-specific RNA degradation, where sequence specificity is determined by the interaction of an siRNA with its complementary sequence within a target RNA (see, e.g., Tuschl, Chem. Biochem. 2001; 2:239-245).

For mammalian systems, RNAi commonly involves the use of dsRNAs that are greater than 500 bp; however, it can also be activated by introduction of either siRNAs (Elbashir, et al., Nature 2001; 411: 494-498) or short hairpin RNAs (shRNAs) bearing a fold back stem-loop structure (Paddison et al., Genes Dev. 2002; 16: 948-958; Sui et al., Proc. Natl. Acad. Sci. USA 2002; 99:5515-5520; Brummelkamp et al., Science 2002; 296:550-553; Paul et al., Nature Biotechnol. 2002; 20:505-508).

The siRNAs are preferably short double stranded nucleic acid duplexes comprising annealed complementary single stranded nucleic acid molecules. Preferably, the siRNAs are short dsRNAs comprising annealed complementary single strand RNAs. siRNAs may also comprise an annealed RNA:DNA duplex, wherein the sense strand of the duplex is a DNA molecule and the antisense strand of the duplex is a RNA molecule.

Preferably, each single stranded nucleic acid molecule of the siRNA duplex is of from about 19 nucleotides to about 27 nucleotides in length. In preferred embodiments, duplexed siRNAs have a 2 or 3 nucleotide 3′ overhang on each strand of the duplex. In preferred embodiments, siRNAs have 5′-phosphate and 3′-hydroxyl groups.

RNAi molecules may include one or more modifications, either to the phosphate-sugar backbone or to the nucleoside. For example, the phosphodiester linkages of natural RNA may be modified to include at least one heteroatom other than oxygen, such as nitrogen or sulfur. In this case, for example, the phosphodiester linkage may be replaced by a phosphothioester linkage. Similarly, bases may be modified to block the activity of adenosine deaminase. Where the RNAi molecule is produced synthetically, or by in vitro transcription, a modified ribonucleoside may be introduced during synthesis or transcription. The skilled artisan will understand that many of the modifications described above for antisense oligonucleotides may also be made to RNAi molecules. Such modifications are well known in the art.

siRNAs may be introduced to a target cell as an annealed duplex siRNA, or as single stranded sense and antisense nucleic acid sequences that, once within the target cell, anneal to form the siRNA duplex. Alternatively, the sense and antisense strands of the siRNA may be encoded on an expression construct that is introduced to the target cell. Upon expression within the target cell, the transcribed sense and antisense strands may anneal to reconstitute the siRNA.

shRNAs typically comprise a single stranded “loop” region connecting complementary inverted repeat sequences that anneal to form a double stranded “stem” region. Structural considerations for shRNA design are discussed, for example, in McManus et al., RNA 2002; 8:842-850. In certain embodiments the shRNA may be a portion of a larger RNA molecule, e.g., as part of a larger RNA that also contains U6 RNA sequences (Paul et al., supra).

In preferred embodiments, the loop of the shRNA is from about 1 to about 9 nucleotides in length. In preferred embodiments the double stranded stem of the shRNA is from about 19 to about 33 base pairs in length. In preferred embodiments, the 3′ end of the shRNA stem has a 3′ overhang. In particularly preferred embodiments, the 3′ overhang of the shRNA stem is from 1 to about 4 nucleotides in length. In preferred embodiments, shRNAs have 5′-phosphate and 3′-hydroxyl groups.

Although RNAi molecules preferably contain nucleotide sequences that are fully complementary to a portion of the target nucleic acid, 100% sequence complementarity between the RNAi probe and the target nucleic acid is not required.

Similar to the above-described antisense oligonucleotides, RNAi molecules can be synthesized by standard methods known in the art, e.g., by use of an automated synthesizer. RNAs produced by such methodologies tend to be highly pure and to anneal efficiently to form siRNA duplexes or shRNA hairpin stem-loop structures. Following chemical synthesis, single stranded RNA molecules are deprotected, annealed to form siRNAs or shRNAs, and purified (e.g., by gel electrophoresis or HPLC). Alternatively, standard procedures may be used for in vitro transcription of RNA from DNA templates carrying RNA polymerase promoter sequences (e.g., T7 or SP6 RNA polymerase promoter sequences). Efficient in vitro protocols for preparation of siRNAs using T7 RNA polymerase have been described (Done and Picard, Nucleic Acids Res. 2002; 30:e46; and Yu et al., Proc. Natl. Acad. Sci. USA 2002; 99:6047-6052). Similarly, an efficient in vitro protocol for preparation of shRNAs using T7 RNA polymerase has been described (Yu et al., supra). The sense and antisense transcripts may be synthesized in two independent reactions and annealed later, or may be synthesized simultaneously in a single reaction.

RNAi molecules may be formed within a cell by transcription of RNA from an expression construct introduced into the cell. For example, both a protocol and an expression construct for in vivo expression of siRNAs are described in Yu et al., supra. The delivery of siRNA to tumors can potentially be achieved via any of several gene delivery “vehicles” that are currently available. These include viral vectors, such as adenovirus, lentivirus, herpes simplex virus, vaccinia virus, and retrovirus, as well as chemical-mediated gene delivery systems (for example, liposomes), or mechanical DNA delivery systems (DNA guns). The oligonucleotides to be expressed for such siRNA-mediated inhibition of gene expression would be between 18 and 28 nucleotides in length. Protocols and expression constructs for in vivo expression of shRNAs have been described (Brummelkamp et al., Science 2002; 296:550-553; Sui et al., supra; Yu et al., supra; McManus et al., supra; Paul et al., supra).

The expression constructs for in vivo production of RNAi molecules comprise RNAi encoding sequences operably linked to elements necessary for the proper transcription of the RNAi encoding sequence(s), including promoter elements and transcription termination signals. Preferred promoters for use in such expression constructs include the polymerase-III HI-RNA promoter (see, e.g., Brummelkamp et al., supra) and the U6 polymerase-III promoter (see, e.g., Sui et al., supra; Paul, et al. supra; and Yu et al., supra). The RNAi expression constructs can further comprise vector sequences that facilitate the cloning of the expression constructs. Standard vectors are known in the art (e.g., pSilencer 2.0-U6 vector, Ambion Inc., Austin, Tex.).

Ribozyme Inhibition

The level of expression of a target polypeptide of the invention can also be inhibited by ribozymes designed based on the nucleotide sequence thereof.

Ribozymes are enzymatic RNA molecules capable of catalyzing the sequence-specific cleavage of RNA (for a review, see Rossi, Current Biology 1994; 4:469-471). The mechanism of ribozyme action involves sequence-specific hybridization of the ribozyme molecule to complementary target RNA, followed by an endonucleolytic cleavage event. The composition of ribozyme molecules must include: (i) one or more sequences complementary to the target RNA; and (ii) a catalytic sequence responsible for RNA cleavage (see, e.g., U.S. Pat. No. 5,093,246).

The use of hammerhead ribozymes is preferred. Hammerhead ribozymes cleave RNAs at locations dictated by flanking regions that form complementary base pairs with the target RNA. The sole requirement is that the target RNA has the following sequence of two bases: 5′-UG-3′. The construction of hammerhead ribozymes is known in the art, and described more fully in Myers, Molecular Biology and Biotechnology: A Comprehensive Desk Reference, VCH Publishers, New York, 1995 (see especially FIG. 4, page 833) and in Haseloff and Gerlach, Nature 1988; 334:585-591.

As in the case of antisense oligonucleotides, ribozymes can be composed of modified oligonucleotides (e.g., for improved stability, targeting, etc.). These can be delivered to cells which express the target polypeptide in vivo. A preferred method of delivery involves using a DNA construct “encoding” the ribozyme under the control of a strong constitutive pol III or pol II promoter, so that transfected cells will produce sufficient quantities of the ribozyme to catalyze cleavage of the target mRNA encoding the target polypeptide. However, because ribozymes, unlike antisense molecules, are catalytic, a lower intracellular concentration may be required to achieve an adequate level of efficacy.

Ribozymes can be prepared by any method known in the art for the synthesis of DNA and RNA molecules, as discussed above. Ribozyme technology is described further in Intracellular Ribozyme Applications: Principals and Protocols, Rossi and Couture eds., Horizon Scientific Press, 1999.

Triple Helix Forming Oligonucleotides (TFOs)

Nucleic acid molecules useful to inhibit expression level of a target polypeptide of the invention via triple helix formation are preferably composed of deoxynucleotides. The base composition of these oligonucleotides is typically designed to promote triple helix formation via Hoogsteen base pairing rules, which generally require sizeable stretches of either purines or pyrimidines to be present on one strand of a duplex. Nucleotide sequences may be pyrimidine-based, resulting in TAT and CGC triplets across the three associated strands of the resulting triple helix. The pyrimidine-rich molecules provide base complementarity to a purine-rich region of a single strand of the duplex in a parallel orientation to that strand. In addition, nucleic acid molecules may be chosen that are purine-rich, e.g., those containing a stretch of G residues. These molecules will form a triple helix with a DNA duplex that is rich in GC pairs, in which the majority of the purine residues are located on a single strand of the targeted duplex, resulting in GGC triplets across the three strands in the triplex.

Alternatively, sequences can be targeted for triple helix formation by creating a so-called “switchback” nucleic acid molecule. Switchback molecules are synthesized in an alternating 5′-3′,3′-5′ manner, such that they base pair with first one strand of a duplex and then the other, eliminating the necessity for a sizeable stretch of either purines or pyrimidines to be present on one strand of a duplex.

Similarly to RNAi molecules, antisense oligonucleotides, and ribozymes, described above, triple helix molecules can be prepared by any method known in the art. These include techniques for chemically synthesizing oligodeoxyribonucleotides and oligoribonucleotides such as, e.g., solid phase phosphoramidite chemical synthesis. Alternatively, RNA molecules can be generated by in vitro or in vivo transcription of DNA sequences “encoding” the particular RNA molecule. Such DNA sequences can be incorporated into a wide variety of vectors that incorporate suitable RNA polymerase promoters such as the T7 or SP6 polymerase promoters. See, Nielsen, P. E. “Triple Helix: Designing a New Molecule of Life”, Scientific American, December, 2008; Egholm, M., et al. “PNA Hybridizes to Complementary Oligonucleotides Obeying the Watson-Crick Hydrogen Bonding Rules.” (1993) Nature, 365, 566-568; Nielsen, P. E. ‘PNA Technology’. Mol Biotechnol. 2004; 26:233-48.

Antibodies and Aptamers

The polypeptide targets described herein, e.g., HSD17B11, HSD17B12, HSD17B14, etc.) can be inhibited (e.g., the level can be reduced) by the administration to or expression in a subject or a cell or tissue thereof, of blocking antibodies or aptamers against the polypeptide.

Antibodies, or their equivalents and derivatives, e.g., intrabodies, or other antagonists of the polypeptide, may be used in accordance with the present methods. Methods for engineering intrabodies (intracellular single chain antibodies) are well known. Intrabodies are specifically targeted to a particular compartment within the cell, providing control over where the inhibitory activity of the treatment is focused. This technology has been successfully applied in the art (for review, see Richardson and Marasco, 1995, TIBTECH vol. 13; Lo et al. (2009) Handb Exp Pharmacol. 181:343-73; Maraasco, W. A. (1997) Gene Therapy 4:11-15; see also, U.S. Pat. Appln. Pub. No. 2001/0024831 by Der Maur et al. and U.S. Pat. No. 6,004,940 by Marasco et al.).

Administration of a suitable dose of the antibody or the antagonist (e.g., aptamer) may serve to block the level (expression or activity) of the polypeptide in order to treat or prevent cancer, e.g., inhibit growth of a breast cancer cell or tumor (e.g., ER+ or ER− breast cancer cell or tumor).

In addition to using antibodies and aptamers to inhibit the levels and/or activity of a target polypeptide, it may also be possible to use other forms of inhibitors. For example, it may be possible to identify antagonists that functionally inhibit the target polypeptide (e.g., HSD17B11, HSD17B12, HSD17B14, etc.). In addition, it may also be possible to interfere with the interaction of the polypeptide with its substrate. Other suitable inhibitors will be apparent to the skilled person.

The antibody (or other inhibitors and antagonists) can be administered by a number of methods. For example, for the administration of intrabodies, one method is set forth by Marasco and Haseltine in PCT WO 94/02610. This method discloses the intracellular delivery of a gene encoding the intrabody. In one embodiment, a gene encoding a single chain antibody is used. In another embodiment, the antibody would contain a nuclear localization sequence. By this method, one can intracellularly express an antibody, which can block activity of the target polypeptide in desired cells.

Aptamers are oligonucleic acid or peptide molecules that bind to a specific target molecule. Aptamers can be used to inhibit gene expression and to interfere with protein interactions and activity. Nucleic acid aptamers are nucleic acid species that have been engineered through repeated rounds of in vitro selection (e.g., by SELEX (systematic evolution of ligands by exponential enrichment)) to bind to various molecular targets such as small molecules, proteins, nucleic acids, and even cells, tissues and organisms. Peptide aptamers consist of a variable peptide loop attached at both ends to a protamersein scaffold. Aptamers are useful in biotechnological and therapeutic applications as they offer molecular recognition properties that rival that of antibodies. Aptamers can be engineered completely in a test tube, are readily produced by chemical synthesis, possess desirable storage properties, and elicit little or no immunogenicity in therapeutic application. Aptamers can be produced using the methodology disclosed in a U.S. Pat. No. 5,270,163 and WO 91/19813.

Small Molecules

Chemical agents, referred to in the art as “small molecule” compounds are typically organic, non-peptide molecules, having a molecular weight less than 10,000 Da, preferably less than 5,000 Da, more preferably less than 1,000 Da, and most preferably less than 500 Da. This class of modulators includes chemically synthesized molecules, for instance, compounds from combinatorial chemical libraries. Synthetic compounds may be rationally designed or identified utilizing the screening methods described below. Methods for generating and obtaining small molecules are well known in the art (Schreiber, Science 2000; 151:1964-1969; Radmann et al., Science 2000; 151:1947-1948).

Non-limiting of small molecule inhibitors (and exemplary dosages for in vitro use in cell-based assays) include, e.g., cyclopamine (e.g., 10 μM) (Selleck Chemicals, cat #S1146), an inhibitor of Smo receptor of Hh ligands; LY2109761 (e.g., 500 nM) (Eli Lilly), an inhibitor of TGFBR kinases; celecoxib (e.g., 100 μM) (LKT laboratories, cat #C1644), an inhibitor of Cox2; 2-5dideoxyadenosine (e.g., 100 μM) (Enzo Life Sciences, cat #BML-CN110-005), an inhibitor of adenylate cyclase; tyrphostin AG1478 (e.g., 10 μM) (Cayman Chemicals, cat #10010244), an inhibitor of EGFR; XAV939 (e.g., 104)(Tocris Bioscience, cat #3748), a Tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin; and picropodophyllotoxin (e.g., 0.5 μM) (Tocris Bioscience, cat #2956), an IGFR inhibitor in which stock solutions (1,000×) are prepared in DMSO.

Non-limiting examples of small molecule agonists include, e.g., the TFGb agonists described in detail in U.S. Pat. No. 8,097,645 to Wyss-Coray et al., the hedgehog (Hh) agonist cyclopaminc (see, King, W K. Journal of Biology 2002, 1:8); the Wnt agonist Calbiochem (EMD Millipore), and the cAMP agonist Alotaketal A described in Huang et al. (J. Am. Chem. Soc., 2012, 134 (21), pp 8806-8809).

In certain embodiments, the above described inhibitors and agonists can be directly targeted to a specific cell type (e.g., CD44+ or CD24+ breast epithelial cells, p27+ or Ki67+ breast epithelial cells, AR+ cells (e.g., AR+ breast epithelial cells), ER+ breast epithelial cells, ER− breast epithelial cells, and combinations thereof, e.g., ER+p27+ cells (e.g., ER+p27+ breast epithelial cells), or AR+p27+ cells (e.g., AR+p27+ breast epithelial cells), etc. The skilled artisan will appreciate that methods for specific cell targeting are well known in the art. By way of non-limiting example, antibodies, e.g., an anti-CD44, anti-CD24, anti-AR, or anti-ER antibody, etc., may be conjugated to an inhibitor or agonist described herein, in order to target the inhibitor or agonist to, for example and without limitation, CD44+, CD24+ or ER+ cells. Further the site of administration (e.g., direct injection into breast tissue and/or breast tumor) can further increase the specificity of cell targeting.

VI. Methods for Predicting a Subject's Risk of Developing Breast Cancer

Provided herein are methods for predicting a subject's risk of developing breast cancer (e.g., ER+ or ER− breast cancer).

In one embodiment, the method comprises (a) determining the frequency in a breast tissue sample of CD44+, CD24− breast epithelial cells and (b) predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of CD44+, CD24− breast epithelial cells is decreased compared to a first control frequency of CD44+, CD24− breast epithelial cells; or (c) predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of CD44+ breast epithelial cells is increased compared to a second control frequency of CD44+, CD24− breast epithelial cells.

In another embodiment, the method comprises: (a) determining the frequency in a breast tissue sample of CD24+ breast epithelial cells and (b) predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of CD24+ breast epithelial cells is increased compared to a first control frequency of CD24+ breast epithelial cells; or (c) predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of CD24+ breast epithelial cells is decreased compared to a second control frequency of CD24+ breast epithelial cells.

As discussed in the Definitions section, above, a “first control frequency” of a cell type (e.g., CD44+ or CD24+ cells, or p27+ cells, Ki67+ cells, etc.) is the frequency of that cell type in a comparable sample from a patient or the average frequency in comparable samples from a plurality of patients known to be at low risk of developing breast cancer (e.g., parous women not expressing BRCA1 or BRCA2 mutations, where the women are premenopausal and/or postmenopausal). In other words, the first control frequency is a “negative” control for an elevated risk of developing breast cancer. As also discussed above, a “second control frequency” of a cell type is the frequency of that cell type in a comparable sample from a patient or the average frequency in comparable samples from a plurality of patients known to be at high risk of developing breast cancer (e.g., pre and/or postmenopausal nulliparous women). In other words, the second control frequency is a “positive” control for an elevated risk of developing the breast cancer. The first and second control frequencies can be simultaneously determined or can be determined before or after the frequency of the relevant cell is determined in the breast cells from the subject for whom the risk prediction is being made.

In a particularly preferred embodiment, the frequency of both CD44+ and CD24+ breast epithelial cells in the sample is determined as described above, and the method comprises predicting that the subject has a relatively elevated risk of developing breast cancer if: (i) the frequency of CD44+, CD24− breast epithelial cells is decreased compared to a first control frequency of CD44+, CD24− breast epithelial cells, and (ii) the frequency of CD24+ breast epithelial cells is increased compared to a first control frequency of CD24+ breast epithelial cells; and step (c) comprises predicting that the subject has a relatively reduced risk of developing breast cancer if: (i) the frequency of CD44+ breast epithelial cells is increased compared to a second control frequency of CD44+, CD24− breast epithelial cells, and (ii) the frequency of CD24+ breast epithelial cells is decreased compared to a second control frequency of CD24+ breast epithelial cells.

In other embodiments, the first and second control frequencies of CD44+ and CD24+ breast epithelial cells, described above, can also be first and second predetermined reference frequencies, respectively (i.e., standards) to which the frequency of the cell type in a test sample is compared.

For example, the predetermined reference frequency for a first control frequency, of CD44+, CD24− breast epithelial cells is preferably in the range of 15-30% or higher of the total breast epithelial cells in the sample. Further, as disclosed herein, a subject considered to have a relatively elevated risk of developing breast cancer will have a decreased frequency of CD44+, CD24− breast epithelial cells relative to that predetermined reference frequency; thus, a subject determined to have a frequency of CD44+, CD24− breast epithelial cells less than 15% would be predicted to have a relatively elevated risk of developing breast cancer. More preferably, a subject determined to have a frequency of CD44+, CD24− breast epithelial cells less than 14%, less than 13%, less than 12%, less than 11%, less than 10%, less than 9%, less than 8%, less than 7%, less than 6%, or less than 5%, is predicted to have a relatively elevated risk of developing breast cancer.

The predetermined reference frequency for a second control frequency of CD44+, CD24− breast epithelial cells is preferably in the range of 15% or less (e.g., less than 15%, less than 14%, less than 13%, less than 12%, less than 11%, less than 10%, etc.) of the total breast epithelial cells in the sample. As disclosed herein, a subject considered to have a relatively reduced risk of developing breast cancer will have an increased frequency of CD44+, CD24− breast epithelial cells relative to the second predetermined reference frequency; thus, a subject determined to have a frequency of CD44+, CD24− breast epithelial cells greater than 15%, preferably greater than 16%, greater than 17%, greater than 18%, greater than 19%, greater than 20%, greater than 21%, greater than 22%, greater than 23%, greater than 24%, greater than 25%, greater than 26%, greater than 27%, greater than 28%, greater than 29%, or greater than 30% is predicted to have a relatively reduced risk of developing breast cancer.

The first predetermined reference frequency of CD24+ breast epithelial cells is preferably 20%, or less than 20%, less than 19%, less than 18%, less than 17%, less than 16%, less than 15%, less than 14%, less than 13%, less than 12%, less than 11%, less than 10%, less than 9%, less than 8%, less than 7%, less than 6%, or less than 5% of the total breast epithelial cells in the sample. As disclosed herein, a subject considered to have a relatively elevated risk of developing breast cancer will have an increased frequency of CD24+ breast epithelial cells relative to the first predetermined reference frequency of CD24+ breast epithelial cells; thus, a subject determined to have a frequency of CD24+ breast epithelial cells greater than 20%, greater than 21%, greater than 22%, greater than 23%, greater than 24%, greater than 25%, greater than 26%, greater than 27%, greater than 28%, greater than 29%, greater than 30%, greater than 31%, greater than 32%, greater than 33%, greater than 34%, greater than 35%, greater than 36%, greater than 37%, greater than 38%, greater than 39%, greater than 40%, greater than 41%, greater than 42%, greater than 43%, greater than 44%, greater than 45%, greater than 46%, greater than 47%, greater than 48%, greater than 49%, or greater than 50% of the total breast epithelial cells in the sample, is predicted to have a relatively elevated risk of developing breast cancer.

The second predetermined reference frequency of CD24+ breast epithelial cells is preferably 20%, or greater than 20%, greater than 21%, greater than 22%, greater than 23%, greater than 24%, greater than 25%, greater than 26%, greater than 27%, greater than 28%, greater than 29%, greater than 30%, greater than 31%, greater than 32%, greater than 33%, greater than 34%, greater than 35%, greater than 36%, greater than 37%, greater than 38%, greater than 39%, greater than 40%, greater than 41%, greater than 42%, greater than 43%, greater than 44%, greater than 45%, greater than 46%, greater than 47%, greater than 48%, greater than 49%, or greater than 50%, of the total breast epithelial cells in the sample. As disclosed herein, a subject considered to have a relatively reduced risk of developing breast cancer will have a decreased frequency of CD24+ breast epithelial cells relative to the second predetermined reference frequency; thus, a subject determined to have a frequency of CD24+ breast epithelial cells less than 20% (e.g., less than 20%, less than 19%, less than 18%, less than 17%, less than 16%, less than 15%, less than 14%, less than 13%, less than 12%, less than 11%, less than 10%, less than 5%, etc.) would be predicted to have a relatively reduced risk of developing breast cancer.

In yet other embodiments, the method for predicting a subject's risk of developing an breast cancer comprises: predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of CD24+ breast epithelial cells is greater than the frequency of CD44+, CD24− breast epithelial cells in the sample; and step (c) comprises predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of CD24+ breast epithelial cells is equal to or less than the frequency of CD44+, CD24− breast epithelial cells in the sample. In still other embodiments, the method for predicting a subject's risk of developing an breast cancer comprises predicting that the subject has a relatively elevated risk of developing breast cancer if the ratio of CD24+ breast epithelial cells to CD44+, CD24− breast epithelial cells in a breast epithelial cell-containing sample from the subject is 2, or greater than 2, greater than 3, greater than 4, greater than 5, greater than 6, greater than 7, greater than 8, greater than 9, or greater than 10; or, predicting that the subject has a relatively reduced risk of developing breast cancer if the ratio of CD24+ breast epithelial cells to CD44+, CD24− breast epithelial cells in a breast epithelial cell-containing sample from the subject is less than 2, preferably less than 1.5, less than 1, less than 0.9, less than 0.8, less than 0.7, less than 0.6, less than 0.5, less than 0.4, less than 0.3, less than 0.2, less than 0.1, less than 0.05, or less than 0.01.

In other embodiments, a method of predicting a subject's risk of developing an estrogen-receptor-positive (ER+) breast cancer is provided, wherein the method comprises: (a) determining the frequency in a breast tissue sample of cells of one or more types of cells, such as, e.g., p27+ breast epithelial cells, Sox17+ breast epithelial cells, Cox2+ breast epithelial cells, Ki67+ breast epithelial cells, ER+, p27+ breast epithelial cells, ER+, Sox17+ breast epithelial cells, ER+, Cox2+ breast epithelial cells, ER+, Ki67+ breast epithelial cells, AR+, p27+ breast epithelial cells, AR+, Sox17+ breast epithelial cells, AR+, Cox2+ breast epithelial cells, and AR+, Ki67+ breast epithelial cells; and (b) predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of the cells of the type is increased compared to a first control frequency of cells of the type; or (c) predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of the cells of the type is decreased compared to a second control frequency of the cells of the type. In a preferred embodiment, the frequencies of two or more, three or more, or all of the cell types (e.g., p27+, Ki67+, Sox17 and/or Cox2+ breast epithelial cells and/or ER+, p27+ breast epithelial cells, ER+, Sox17+ breast epithelial cells, ER+, Cox2+ breast epithelial cells, ER+, Ki67+ breast epithelial cells, AR+, p27+ breast epithelial cells, AR+, Sox17+ breast epithelial cells, AR+, Cox2+ breast epithelial cells, and/or AR+, Ki67+ breast epithelial cells are determined, as described above.

In one embodiment of the above method, the frequency of the p27+ breast epithelial cells, Ki67+ breast epithelial cells, Sox17+ breast epithelial cells, Cox2+ breast epithelial cells, ER+, p27+ breast epithelial cells, ER+, Sox17+ breast epithelial cells, ER+, Cox2+ breast epithelial cells, ER+, Ki67+ breast epithelial cells, AR+, p27+ breast epithelial cells, AR+, Sox17+ breast epithelial cells, AR+, Cox2+ breast epithelial cells, and/or AR+, Ki67+ breast epithelial cells is increased relative to the first control frequency by at least 2-fold, at least 3-fold, at least 4-fold, at least 5-fold, at least 10-fold, or more. Also preferably, in the above method, the frequency of the p27+, Ki67+, Sox17 and/or Cox2+ breast epithelial cells is decreased relative to the second control frequency by at least 2-fold, at least 3-fold, at least 4-fold, at least 5-fold, at least 10-fold, or more.

In another embodiment, step (b) of the method described above comprises predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of p27+ breast epithelial cells is 15% or greater (e.g., 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, 40% or greater) of the breast epithelial cells in the sample; and step (c) comprises predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of p27+ breast epithelial cells is less than 15% (e.g., 14%, 13%, 12%, 11%, 10%, 9%, 8%, 7%, 6%, 5%, 4%, 3%, 2%, 1% or less) of the breast epithelial cells in the sample.

In another embodiment, step (b) of the method described above comprises predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of Ki67+ breast epithelial cells is 2% or greater or 3% of greater of the breast epithelial cells in the sample, and step (c) comprises predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of Ki67+ breast epithelial cells is less than 2% (e.g., 1.9%, 1.8%, 1.7%, 1.6%, 1.5%, 1.0%, 0.5%, or 0%) of the breast epithelial cells in the sample.

In another embodiment, step (b) of the method described above comprises predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of p27+ breast epithelial cells is 15% or greater (e.g., 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, 40% or greater) of the breast epithelial cells in the sample; and step (c) comprises predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of p27+ breast epithelial cells is less than 15% (e.g., 14%, 13%, 12%, 11%, 10%, 9%, 8%, 7%, 6%, 5%, 4%, 3%, 2%, 1% or less) of the breast epithelial cells in the sample.

In another embodiment, step (b) of the method described above comprises predicting that the subject has a relatively elevated risk of developing breast cancer if the frequency of p27+, AR+ breast epithelial cells is 10% or greater (e.g., 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%, 19%, 20%, 21%, 22%, 23%, 24%, 25%, 26%, 27%, 28%, 29%, 30%, 31%, 32%, 33%, 34%, 35%, 36%, 37%, 38%, 39%, 40% or greater) of the breast epithelial cells in the sample; and step (c) comprises predicting that the subject has a relatively reduced risk of developing breast cancer if the frequency of p27+ breast epithelial cells is less than 10% (e.g., 9%, 8%, 7%, 6%, 5%, 4%, 3%, 2%, 1% or less) of the breast epithelial cells in the sample.

In yet other embodiments, a method of predicting a subject's risk of developing an breast cancer is provided, wherein the method comprises: (a) determining the expression level in a breast tissue sample from a subject of at least one marker, e.g., p27, Sox17 and Cox2; and (b) predicting that the subject has a relatively elevated risk of developing breast cancer if the expression level of the at least one marker is increased compared to a first control level of the at least one marker; or (c) predicting that the subject has a relatively reduced risk of developing breast cancer if the expression level of the at least one marker is decreased compared to a second control level of the at least one marker. Methods for determining the expression level of markers p27, Sox17 and Cox2 (e.g., QPCR, FACS, immunohistochemistry, Western blot, ELISA) are described above.

In step (b) in the above method, preferably, the expression level of p27, Sox17 and/or Cox2 (e.g., mRNA and/or polypeptide) is increased by at least 2-fold, at least 3-fold, at least 4-fold, at least 5-fold, at least 6-fold, at least 7-fold, at least 8-fold, at least 9-fold, at least 10-fold, at least 20-fold or greater, compared to the first control level (i.e., a control level from a subject known to be at low risk of developing breast cancer). In step (c) in the above method, preferably, the expression level of p27, Sox17 and/or Cox2 (e.g., mRNA and/or polypeptide) is decreased by at least 2-fold, at least 3-fold, at least 4-fold, at least 5-fold, at least 6-fold, at least 7-fold, at least 8-fold, at least 9-fold, at least 10-fold, at least 20-fold or more, compared to the second control level (i.e., a control level from a subject known to be at high risk of developing breast cancer).

In still other embodiments, methods of predicting the risk of developing breast cancer are provided, which comprise determining a parity/nulliparity-associated gene expression signature in a sample comprising breast epithelial cells. Also provided are methods of predicting breast cancer disease outcome by testing for a parity/nulliparity-associated gene expression signature in breast cancer cells.

As described above and in Example 10, the genes that were shown to be upregulated or downregulated in FIG. 28 make up a parity/nulliparity-related gene signature. Further, the genes for which the expression profile is shown in FIG. 28 are described in detail in Table 18, below. Of course, the skilled artisan will appreciate that a parity/nulliparity-related gene signature can, but does not necessarily comprise all of the genes shown in Table 18. Such gene signature comprises 2 or more, 3 or more, 4 or more, 5 or more, 10 or more, 15 or more, 20 or more, 30 or more, 40 or more, 50 or more, or 100 or more of the genes shown in Table 18.

Further, for each of the genes shown in Table 18, the disease outcome based on the expression of a particular gene in the expression is shown (i.e., a prognosis of “good” or “bad”). Thus, the skilled artisan can select one or more genes from the list of genes in Table 18 that are correlated with a “good” prognosis and/or one or more genes associated with a “bad” prognosis, and assemble the selected genes in a custom gene signature. A subject's gene expression profile for the genes in the custom signature can be determined, and for example, if the subject expresses more of the genes associated with a “bad” prognosis than the genes associated with a “good” prognosis, then the patient's disease outcome is predicted to be “bad” or “poor”, whereas as subject expressing more of the “good” prognosis genes is predicted to have a “good” prognosis (i.e., more likely to survive the disease).

The above described methods of predicting a subject's risk of developing cancer and for determining a disc outcome (e.g., prognosis), can be used, e.g., by the subject's physician to determine the best course of treatment or prophylaxis to administer to the subject in need thereof, as well as other courses of action. For example, such methods can further comprise administering to a subject identified as having an increased risk of developing breast cancer, or a subject diagnosed with breast cancer and determined according to the above methods to have a bad prognosis, a therapy or therapeutic agent for treating, reducing the risk of developing, or preventing breast cancer (e.g., ER+ or ER− breast cancer). In other embodiments, the methods can comprise performing additional diagnostic assays to confirm the diagnosis (e.g., imaging, biopsy, etc.), recording the diagnosis in a database or medical history (e.g., medical records) of the subject, performing diagnostic tests on a family member of the subject, selecting the subject for increased monitoring or periodically monitoring the health of the subject (e.g., for development of signs or symptoms of breast cancer, e.g., tumor development or tumor size changes (e.g., increased or decreased size), such as e.g., clinical breast exam, mammography, MRI, or other suitable imaging or other diagnostic method(s) known in the art.

VII. Administration

Compositions and formulations comprising an inhibitor or agonist of the invention (e.g., an inhibitor or agonist of a gene or polypeptide mediating a function in a pathway that is upregulated or downregulated in breast epithelial cells of nulliparous women), can be administered topically, parenterally, orally, by inhalation, as a suppository, or by other methods known in the art. The term “parenteral” includes injection (for example, intravenous, intraperitoneal, epidural, intrathecal, intramuscular, intraluminal, intratracheal or subcutaneous). Exemplary routes of administration include, e.g., intravenous, intraductal, and intratumoral.

While it is possible to use an inhibitor or agonist of the invention for therapy as is, it may be preferable to administer an inhibitor or agonist as a pharmaceutical formulation, e.g., in admixture with a suitable pharmaceutical excipient, diluent, or carrier selected with regard to the intended route of administration and standard pharmaceutical practice. Pharmaceutical formulations comprise at least one active compound, or a pharmaceutically acceptable derivative thereof, in association with a pharmaceutically acceptable excipient, diluent, and/or carrier. The excipient, diluent and/or carrier must be “acceptable,” as defined above.

Administration of a composition or formulation of the invention can be once a day, twice a day, or more often. Frequency may be decreased during a treatment maintenance phase of the disease or disorder, e.g., once every second or third day instead of every day or twice a day. The dose and the administration frequency will depend on the clinical signs, which confirm maintenance of the remission phase, with the reduction or absence of at least one or more preferably more than one clinical signs of the acute phase known to the person skilled in the art. More generally, dose and frequency will depend in part on recession of pathological signs and clinical and subclinical symptoms of a disease condition or disorder contemplated for treatment with the present compounds.

It will be appreciated that the amount of an inhibitor required for use in treatment will vary with the route of administration, the nature of the condition for which treatment is required, and the age, body weight and condition of the patient, and will be ultimately at the discretion of the attendant physician or veterinarian. Compositions will typically contain an effective amount of the active agent(s), alone or in combination. Preliminary doses can be determined according to animal tests, and the scaling of dosages for human administration can be performed according to art-accepted practices.

Length of treatment, i.e., number of days, will be readily determined by a physician treating the subject; however the number of days of treatment may range from 1 day to about 20 days. As provided by the present methods, and discussed below, the efficacy of treatment can be monitored during the course of treatment to determine whether the treatment has been successful, or whether additional (or modified) treatment is necessary.

VIII. Methods of Treating and Preventing Breast Cancer

Provided herein are methods for treating and preventing estrogen-receptor-positive (ER+) breast cancer in a subject. Typically, a subject that can be administered an inhibitor or agonist, or composition, e.g., pharmaceutical composition, comprising one or more inhibitors or agonists described above is a premenopausal or postmenopausal woman. In some embodiments, the subject has a BRCA-1 or BRCA-2 germline mutation.

In certain embodiments, methods of treating breast cancer (e.g., ER+ or ER− breast cancer) in a subject are provided that comprise administering to the subject a composition comprising an inhibitor of a pathway that has increased activity in breast epithelial cells (e.g., CD44+, CD24− breast epithelial cells) of nulliparous women compared to the activity in breast epithelial cells of parous women (i.e. a pathway active in nulliparous breast epithelial cells). In other embodiments an agonist of a pathway that has decreased activity in breast epithelial cells (e.g., CD44+, CD24− breast epithelial cells) of nulliparous women compared to the activity in breast epithelial cells of parous women (i.e. a pathway active in parous breast epithelial cells) can be administered. Such inhibitors and agonists and the target pathways and genes in those pathways are described in detail above.

In other embodiments, methods of preventing breast cancer (e.g., ER+ or ER− breast cancer) in a subject are provided that comprise administering to a subject at risk of developing breast cancer an inhibitor of a pathway active in nulliparous breast epithelial cells (e.g., CD44+, CD24− breast epithelial cells). For example, the pathway can include a mediator molecule such as cAMP, EGFR, Cox2, Hh, TGFBR, and IGFR, as described above. In another embodiment, the method of preventing breast cancer in a subject comprises administering to the subject an agonist of a pathway active in parous breast epithelial cells (e.g., CD44+, CD24− breast epithelial cells) (e.g., an agonist of Hakai/CBLL1, CASP8, SCR1B, LLGL2, PI3K/AKT signaling, and apoptosis).

In certain embodiments, an inhibitor or agonist or any combination of 2 or more, 3 or more, 4 or more, or 5 or more inhibitors and/or agonists of the above-described target genes and/or polypeptides can be administered in a combination therapy to a subject for the treatment or prevention of breast cancer (e.g., ER+ or ER− breast cancer).

The skilled artisan will appreciate that other combinations of inhibitors and/or agonists are possible, so long as the combination results in the treatment or prevention of breast cancer.

The skilled artisan will also appreciate that the methods of treating breast cancer described herein (e.g., administration of one or more of the inhibitors and agonists described above) may also be administered in a combination therapy with other treatments, e.g. other cancer therapies. Non-limiting examples of such cancer therapies include, e.g., chemotherapy, radiation therapy, biological therapy (e.g., antibodies, biological modifiers (cytokines, growth factors, lymphokines, chemokines, etc.), immune cell therapies (LAK cells, tumor specific CTL, etc.), anti-angiogenic therapy, surgery, and combinations thereof.

Chemotherapeutic agents, include for example: taxanes such as taxol, taxotere or their analogues; alkylating agents such as cyclophosphamide, isosfamide, melphalan, hexamethylmelamine, thiotepa or dacarbazine; antimetabolites such as pyrimidine analogues, for instance 5-fluorouracil, cytarabine, capecitabine, and gemcitabine or its analogues such as 2-fluorodeoxycytidine; folic acid analogues such as methotrexate, idatrexate or trimetrexate; spindle poisons including vinca alkaloids such as vinblastine, vincristine, vinorelbine and vindesine, or their synthetic analogues such as navelbine, or estramustine and a taxoid; platinum compounds such as cisplatin; epipodophyllotoxins such as etoposide or teniposide; antibiotics such as daunorubicin, doxorubicin, bleomycin or mitomycin, enzymes such as L-asparaginase, topoisomerase inhibitors such as topotecan or pyridobenzoindole derivatives; and various agents such as procarbazine, mitoxantrone, and biological response modifiers or growth factor inhibitors such as interferons or interleukins. Other chemotherapeutic agents include, though are not limited to, a p38/JAK kinase inhibitor, e.g., SB203580; a phosphatidyl inositol-3 kinase (PI3K) inhibitor, e.g., LY294002; a MAPK inhibitor, e.g. PD98059; a JAK inhibitor, e.g., AG490; preferred chemotherapeutics such as UCN-01, NCS, mitomycin C (MMC), NCS, and anisomycin; taxoids in addition to those describe above (e.g., as disclosed in U.S. Pat. Nos. 4,857,653; 4,814,470; 4,924,011, 5,290,957; 5,292,921; 5,438,072; 5,587,493; European Patent No. 0 253 738; and PCT Publication Nos. WO 91/17976, WO 93/00928, WO 93/00929, and WO 96/01815. In other embodiments, a cancer therapy can include but is not limited to administration of cytokines and growth factors such as interferon (IFN)-gamma, tumor necrosis factor (TNF)-alpha, TNF-beta, and/or similar cytokines, or an antagonist of a tumor growth factor (e.g., TGF-β and IL-10). Antiangiogenic agents, include, e.g., endostatin, angiostatin, TNP-470, Caplostatin (Stachi-Fainaro et al., Cancer Cell 7(3), 251 (2005)). Drugs that interfere with intracellular protein synthesis can also be used in the methods of the present invention; such drugs are known to those skilled in the art and include puromycin, cycloheximide, and ribonuclease.

For radiation therapy, common sources of radiation used for cancer treatment include, but are not limited to, high-energy photons that come from radioactive sources such as cobalt, cesium, iodine, palladium, or a linear accelerator, proton beams; neutron beams (often used for cancers of the head, neck, and prostate and for inoperable tumors), x or gamma radiation, electron beams, etc.

It is well known that radioisotopes, drugs, and toxins can be conjugated to antibodies or antibody fragments which specifically bind to markers which are produced by or associated with cancer cells, and that such antibody conjugates can be used to target the radioisotopes, drugs or toxins to tumor sites to enhance their therapeutic efficacy and minimize side effects. Examples of these agents and methods are reviewed in Wawrzynczak and Thorpe (in Introduction to the Cellular and Molecular Biology of Cancer, L. M. Franks and N. M. Teich, eds, Chapter 18, pp. 378-410, Oxford University Press. Oxford, 1986), in Immunoconjugates: Antibody Conjugates in Radioimaging and Therapy of Cancer (C. W. Vogel, ed., 3-300, Oxford University Press, N.Y., 1987), in Dillman, R. O. (CRC Critical Reviews in Oncology/Hematology 1:357, CRC Press, Inc., 1984), in Pastan et al. (Cell 47:641, 1986) in Vitetta et al. (Science 238:1098-1104, 1987) and in Brady et al. (Int. J. Rad. Oncol. Biol. Phys. 13:1535-1544, 1987). Other examples of the use of immunoconjugates for cancer and other forms of therapy have been disclosed, inter alia, in U.S. Pat. Nos. 4,331,647, 4,348,376, 4,361,544, 4,468,457, 4,444,744, 4,460,459, 4,460,561 4,624,846, 4,818,709, 4,046,722, 4,671,958, 4,046,784, 5,332,567, 5,443,953, 5,541,297, 5,601,825, 5,637,288, 5,677,427, 5,686,578, 5,698,178, 5,789,554, 5,922,302, 6,187,287, and 6,319,500.

IX. Methods for Determining Efficacy of a Breast Cancer Therapy

In certain embodiments, methods for determining the efficacy of a breast cancer therapy (including prophylactic therapy) are provided. The therapy can be a therapy described herein or any other conventional breast cancer therapy. In one embodiment, the efficacy of a cancer therapy is determined by comparing a subject's parity/nulliparity-related gene expression profile before treatment for the breast cancer to the subject's parity/nulliparity-related gene expression profile during or after the treatment. Typically, a subject that is in need of breast cancer treatment (including prophylactic therapy, e.g., for a subject determined to have an elevated risk of developing breast cancer) will have a parity/nulliparity-related gene expression profile that most closely resembles (i.e., is the same or similar to) the gene signature for nulliparous women. After a successful therapy, it is expected that the subject's gene expression profile will more closely resemble the parity/nulliparity-related gene expression profile of parous women, as described herein (e.g., FIG. 28 and Table 18). A gene signature not resembling the gene expression profile of parous women is an indication that the treatment was not successful, and further treatment or a different treatment is needed.

In other embodiments, a method for determining efficacy of an breast cancer therapy (including prophylactic therapy) comprises measuring the level of a specific gene and/or polypeptide before and after (or during the therapy). For example, as described above, in certain embodiments a method for treating or preventing breast cancer comprises administering an inhibitor or agonist of a specific gene or polypeptide. The level or activity of the target gene or polypeptide can be measured before or at the beginning of treatment, and then again during of or after treatment; typically, when an inhibitor is administered as a cancer therapy, the inhibition and therapy is deemed effective if the level or activity of the target gene or polypeptide is decreased by at least 2-fold, at least 3-fold, at least 4-fold, at least 5-fold, at least 10-fold, or more, relative to the level of the target gene or polypeptide at the beginning of or before commencement of the cancer therapy. Typically, when an agonist is administered as a cancer therapy, the inhibition and therapy is deemed effective if the level or activity of the target gene or polypeptide is increased by at least 2-fold, at least 3-fold, at least 4-fold, at least 5-fold, at least 10-fold, or more, relative to the level of the target gene or polypeptide at the beginning of or before commencement of the cancer therapy.

The above described methods can further comprise administering to the subject (e.g., a subject in which the efficacy of the breast cancer therapy was determined to be poor or not optimal) an additional therapy or therapeutic agent for treating, reducing the risk of developing, or preventing breast cancer (e.g., ER+ or ER− breast cancer). In other embodiments, the methods can comprise recording the results in a database or medical history (e.g., medical records) of the subject, selecting the subject for increased monitoring or periodically monitoring the health of the subject (e.g., for development or changes in the signs or symptoms of the breast cancer, e.g., tumor development and/or changes in tumor size (e.g., increased or decreased size), such as e.g., clinical breast exam, mammography, MRI, or other suitable imaging or other diagnostic method(s) known in the art.

Methods for determining the level of a target gene or polypeptide are well known in the art, as described above.

As above, such methods can be conducted in parallel, or before or after, conventional methods for determining success of a treatment, such as, e.g. measuring tumor size or other symptoms of breast cancer known in the art.

X. Kits

In certain embodiments, kits are provided for predicting a subject's risk of developing breast cancer. In other embodiments, kits are provided for predicting a subject's breast cancer disease outcome (i.e., prognosis, e.g., likeliness to survive the disease). In other embodiments, kits are provided for treating breast cancer. In still other embodiments, kits are provided for determining the efficacy of a cancer therapy.

The above kits can comprise means (e.g., reagents, dishes, solid substrates (e.g., microarray slides, ELISA plates, multiplex beads), solutions, media, buffers, etc.) for determining the level of expression or activity of one or more of the genes and/or pathways described herein. Such kits can further comprise instructions for use, e.g., guidelines for determining the efficacy of a cancer therapy, or for predicting a subject's risk of developing breast cancer, based on the level of expression or activity of the one or more genes detected using the kit.

Other kits comprise means for determining (e.g., reagents, dishes, solid substrates (e.g., microarray slides, ELISA plates, multiplex beads), solutions, media, buffers, etc.) the frequency of breast epithelial cell types (e.g., the frequency of CD44+, CD24− breast epithelial cells, CD24+ breast epithelial cells, CD10+ breast epithelial cells, p27+ breast epithelial cells, Ki67+ breast epithelial cells, Sox17+ breast epithelial cells and/or Cox2+ breast epithelial cells, and/or ER+, p27+ breast epithelial cells, ER+, Sox17+ breast epithelial cells, ER+, Cox2+ breast epithelial cells, ER+, Ki67+ breast epithelial cells, AR+, p27+ breast epithelial cells, AR+, Sox17+ breast epithelial cells, AR+, Cox2+ breast epithelial cells, and/or AR+, Ki67+ breast epithelial cells). Such kits can comprise means for detecting expression (e.g., mRNA and/or protein) levels of one or more of the markers (e.g., CD44, CD24, CD10, p27, Ki67, Sox17, and/or Cox2) of the cell types described above. Such kits can also comprise instructions for determining a subject's risk of developing breast cancer based on the frequencies of those cell types determined. The frequencies that indicate an elevated or reduced risk of developing breast cancer are disclosed above and in the present Examples.

Other kits can comprise means for determining a parity/nulliparity gene expression profile. For example, such kits can comprise a microarray slide or slides comprising probes for two or more genes making up the parity/nulliparity gene expression profile, or means for performing PCR (e.g., QPCR), such as forward and reverse primers, reverse transcriptase, plates, and/or other PCR reagents. Such kits can further comprise instructions for determining a subject's disease outcome based on the subject's parity/nulliparity gene expression profile, as described above and in the present Examples, and may also provide a standard or reference gene expression profile for comparison.

Other kits comprise one or more inhibitors or agonists of pathways active in nulliparous or parous breast epithelial cells (e.g. CD44+, CD24− breast epithelial cells), as described herein, for the treatment or prevention of breast cancer (e.g., ER+ or ER− breast cancer), and, optionally instructions for use (e.g. administration and/or dosage).

In other embodiments, a kit comprises an array containing a substrate having at least 10, 25, 50, 100, 200, 500, or 1,000 addresses, wherein each address has disposed thereon a capture probe that includes: (a) a nucleic acid sequence consisting of a tag nucleotide sequence for the detection of a gene identified in Tables 4, 5, 6, 7 and/or 18 (e.g., HSD17B11, HSD17B12, HSD17B14, HSP90AB1 (GenBank Accession No. AAH09206), PSA (KLK3), NCOR1, NCOR2, NCOA4, NCOA7, SFRP2, SFRP4, VEGFA, NOTCH1, FN1, ITGA4, ITGB1, TSPAN6, RhoA, RAC1, CDC42, PHB4, BCL2L11, TNFRSF4, BMPR2, CASP8, PP2A, PIK3CG, ILK, PDPK1, Hakai/CBLL1, SCRIB, and LLGL2, MAP2K4 (GenBank Accession No. NM_003010.2), PTP4A2 (GenBank Accession No. NM_080391.3), EPHB4 (GenBank Accession No. NM_004444), SPARC (GenBank Accession No. NM_003118.3), RAB32 (GenBank Accession No. NM_006834.3), FIGF (GenBank Accession No. NM_004469.4), SNX3 (GenBank Accession Nos. NM_003795.4, NM_152827.2), GADD45A (GenBank Accession Nos. NM_001924.3, NM_001199741.1, NM_001199742.1), ANXA3 (GenBank Accession Nos. NM_005139.2), and HSPA2 (GenBank Accession No. NM_021979.3)); and (b) the complement of the nucleic acid sequence.

Another kit provided herein contains at least 10 antibodies each of which is specific for a different protein encoded by a gene identified in Tables 4, 5, 6, 7 and/or 18. The antibodies can be, for example, but not limited to, specific for a protein such as HSD17B11, HSD17B12, HSD17B14, HSP90AB1 (GenBank Accession No. AAH09206), PSA (KLK3), NCOR1, NCOR2, NCOA4, NCOA7, SFRP2, SFRP4, VEGFA, NOTCH1, FN1, ITGA4, ITGB1, TSPAN6, RhoA, RAC1, CDC42, PHB4, BCL2L11, TNFRSF4, BMPR2, CASP8, PP2A, PIK3CG, ILK, PDPK1, Hakai/CBLL1, SCRIB, and LLGL2, MAP2K4 (GenBank Accession No. NM_003010.2), PTP4A2 (GenBank Accession No. NM_080391.3), EPHB4 (GenBank Accession No. NM_004444), SPARC (GenBank Accession No. NM_003118.3), RAB32 (GenBank Accession No. NM_006834.3), FIGF (GenBank Accession No. NM_004469.4), SNX3 (GenBank Accession Nos. NM_003795.4, NM_152827.2), GADD45A (GenBank Accession Nos. NM_001924.3, NM_001199741.1, NM_001199742.1), ANXA3 (GenBank Accession Nos. NM_005139.2), and HSPA2 (GenBank Accession No. NM_021979.3). The kit can contain at least 5 antibodies, at least 10 antibodies, at least 15 antibodies, at least 25 antibodies; at least 50 antibodies; at least 100 antibodies; at least 200 antibodies; or at least 500 antibodies.

The kits, regardless of type, will generally comprise one or more containers into which the biological agents (e.g. inhibitors) are placed and, preferably, suitably aliquoted. The components of the kits may be packaged either in aqueous media or in lyophilized form.

In accordance with the present invention, there may be employed conventional molecular biology, microbiology, recombinant DNA, immunology, cell biology and other related techniques within the skill of the art. See, e.g., Sambrook et al., (2001) Molecular Cloning: A Laboratory Manual. 3rd ed. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, N.Y.; Sambrook et al., (1989) Molecular Cloning: A Laboratory Manual. 2nd ed. Cold Spring Harbor Laboratory Press: Cold Spring Harbor, N.Y.; Ausubel et al., eds. (2005) Current Protocols in Molecular Biology. John Wiley and Sons, Inc.: Hoboken, N.J.; Bonifacino et al., eds. (2005) Current Protocols in Cell Biology. John Wiley and Sons, Inc.: Hoboken, N.J.; Coligan et al., eds. (2005) Current Protocols in Immunology, John Wiley and Sons, Inc.: Hoboken, N.J.; Coico et al., eds. (2005) Current Protocols in Microbiology, John Wiley and Sons, Inc.: Hoboken, N.J.; Coligan et al., eds. (2005) Current Protocols in Protein Science, John Wiley and Sons, Inc.: Hoboken, N.J.; Enna et al., eds. (2005) Current Protocols in Pharmacology John Wiley and Sons, Inc.: Hoboken, N.J.; Hames et al., eds. (1999) Protein Expression: A Practical Approach. Oxford University Press: Oxford; Freshney (2000) Culture of Animal Cells: A Manual of Basic Technique. 4th ed. Wiley-Liss; among others. The Current Protocols listed above are updated several times every year.

The following examples are meant to illustrate, not limit, the invention.

EXAMPLES Example 1: Materials and Methods

The following are the materials and methods used in the Examples set forth below.

FACS (Fluorescence Activated Cell Sorting)

A single-cell suspension of human mammary epithelial cells was obtained from organoids after trypsinization (5 mins, 37° C.) and filtration through 40 μm cell strainers. Leukocytes, fibroblasts, and endothelial cells were removed by immuno-magnetic bead purification using cell-type-specific surface markers essentially as previously described [Bloushtain-Qimron, et al. (2008). Proc Natl Acad Sci USA 105, 14076-14081; Shipitsin, M., et al. (2007). Cancer Cell 11, 259-273]. Cells were re-suspended in ice cold PBE (0.5% BSA and 2 mM EDTA in PBS) at 2×10⁶ cells/ml. 2×10⁵ cells from each sample were used for multicolor FACS analysis. Cells were stained with propidium iodine (PI, Sigma), FITC conjugated anti-human EpCAM (Dako, clone Ber-Ep4), PE-conjugated anti-human CD49f (BD, clone GoH3), PE/Cy7-conjugated anti-human CD10 (Biolegend, Clone HI10a), APC-conjugated anti-human CD24 (Biolegend, clone ML5), and purified anti-human CD44 (BD, Clone 515). CD44 antibody was pre-labeled with Zenon Alexa 405 mouse IgG1 kit (Invitrogen). Only PI-negative (viable cells) were used to calculate the relative fraction of each cell population.

Multicolor Immunofluorescence and Immunohistochemical Analyses

Multicolor immunofluorescence for CD44 (Neomarkers, clone 156-3C11, mouse monoclonal IgG2), CD24 (SWAII clone, generously provided by Dr. Peter Altevogt (German Cancer Research Center, Heidelberg, Germany), mouse monoclonal IgG2), p27 (BD Biosciences, clone 57/Kip1/p27, mouse monoclonal IgG1), Sox17 (R&D Systems, clone 245013, mouse monoclonal IgG3), COX2 (Cayman Chemical, clone CX229, mouse monoclonal IgG1), Ki67 (DAKO, clone MIB-1, mouse monoclonal IgG1), Ki67 (Abeam, #16667, rabbit monoclonal) and bromodeoxyuridine (BrdU, Roche, clone BMC9318, mouse monoclonal IgG1), CD10 (DAKO M7308), p63 clone 4A4 (Santa Cruz SC-8431), SMA clone 1A4 (DAKO M0851), Axin2 clone 354214 (R&D systems MAB6078), Phosphor-EGF Receptor (Tyr1173) clone 53A5 (Cell Signaling #4407), Phospho-Smad2 (Ser 465/467) (Cell Signaling #3101), Gata3 (Santa Cruz SC-268), estrogen receptor (clone SP1, Thermo Scientific RM-9101), androgen receptor (clone D6F11, Cell Signalling #5153), and bromodeoxyuridine (BrdU, Roche, clone BMC9318), was performed using whole sections of formalin fixed paraffin embedded (FFPE) normal human breast tissue.

The tissues were deparaffinized in xylene and hydrated in a series of 100%, 70%, 50% and 0% ethanol solutions. After heat-induced antigen retrieval in citrate buffer (pH 6), the samples were blocked with goat serum and sequentially stained with the different primary and secondary antibodies. The sequential staining was optimized to avoid cross-reaction between antibodies and was performed as follows: monoclonal (IgG2a) antibody anti-CD44 (1:100 dilution) for one hour at room temperature; goat anti-mouse IgG2a Alexa555-conjugated (Invitrogen, 1:100 dilution) for 30 minutes at room temperature; monoclonal antibody anti-p27 (1:100 dilution) or monoclonal antibody anti-Sox17 (1:50 dilution) or anti-COX2 (1:50 dilution), and monoclonal antibody anti-CD24 (1:25 dilution) biotin labeled (Zenon® Biotin-XX Rabbit IgG Labeling Kit, Invitrogen), p63 (1:100 dilution), SMA (1:80 dilution), CD10 (1:100 dilution), Gata3 (1:50 dilution) for one hour at room temperature; goat anti-mouse IgG1 Alexa 488-conjugated (Invitrogen, 1:100 dilution, for detection of p27 or COX2), goat anti-mouse Alexa 488/555/647 (Invitrogen 1:100 dilution, for detection of p63, SMA, CD10 and Gata3) or goat anti-mouse IgG3 Alexa 488-conjugated (Invitrogen, 1:100 dilution, for detection of Sox17) and streptavidin Alexa-647 conjugated for 30 minutes at room temperature.

The multicolor immunofluorescence for p27 and Ki67 was performed by incubating the samples with monoclonal antibody anti-p27 (1:100 dilution) and polyclonal antibody anti-Ki67 (1:50 dilution) for one hour at room temperature followed by goat anti-mouse IgG1 Alexa 555-conjugated (Invitrogen, 1:100 dilution, for detection of p27) and goat anti-rabbit Alexa 488-conjugated (Invitrogen, 1:100 dilution, for detection of Ki67) for 30 minutes at room temperature. Multicolor immunofluorescence for pSMAD2 (1:50 dilution), pEGFR (1:50 dilution) and Axin2 (1:20 dilution) were performed by incubation for 2 h at room temperature or overnight at 4° C. followed by secondary antibody Rabbit Alexa 488 conjugated (Invitrogen, 1:100 dilution for pSMAD2 and pEGFR) or mouse IgG1 Alexa-488 conjugated (Invitrogen 1:100 dilution) for Axin2 for 30 minutes at room temperature.

The samples were washed twice with PBS-Tween 0.05% between incubations and protected for long-term storage with VECTASHIELD HardSet Mounting Medium with DAPI (Vector laboratories, cat #H-1500). Before image analysis, the samples were stored at −20° C. for at least 48 hours. Different immunofluorescence images from multiple areas of each sample were acquired with a Nikon Ti microscope attached to a Yokogawa spinning-disk confocal unit, 60× plan apo objective, and Orca-ER camera controlled by Andor iQ software. For the immunohistochemical detection of Sox17 and COX2 the samples were stained with antibodies against Sox17 and COX2 as above, and then incubated with anti-mouse IgG biotinylated antibody (1:100 dilution) for 30 minutes at room temperature followed by the ABC peroxidase System (Vectastain®, ABC System Vector Laboratories). DAB (3,3′-diaminodbenzidine) was used as colorimetric substrate and the signal was enhanced by the addition of 0.04% of nickel chloride. The slides were finally counterstained with Methyl green.

Scoring for the expression of each marker was done as follows: p27 fluorescence intensity was scored in the nuclei of 20 randomly selected cells using the ImageJ 1.43r software; Sox17 and COX2 expression was inferred by the combination of two variables: 1) the percentage cells expressing each marker, and 2) the intensity of each marker transformed into a categorical variable based on 0 no expression, 1 weak expression, 2 moderate expression and 3 high expression; the percentage of p27+, Ki67+ and BrdU+ cells was estimated by counting an average of 1000 cells/sample in the case of the mammary epithelium for premenopausal, postmenopausal and high-low density cases, and an average of 2,000 cells in the case of the tissue slices cultures. % of pSMAD2+ cells was estimated by counting an average of 600 cells/sample. For pEGFR and Axin2 fluorescence intensity measurement, mean fluorescence intensity was measured using Image J 1.43r software by counting an average of 600 cells/sample corrected by area and subtracting the average of background fluorescence intensity. RGB profile was also generated using Image J 1.43 software. For multicolor immunofluorescence of p27 and ER, p27 (1:100 dilution) and ER (1:500 dilution) antibodies were incubated overnight at 40 C followed by incubation at RT for 1 h with subsequent staining by goat anti-mouse IgG1 Alexa 555-conjugated (Invitrogen, 1:100 dilution, for detection of p27) while detection of ER antibody was performed by Biotinylated anti Rabbit 20 antibody (1:100 dilution) using Perkin Elmer TSATM INDIRECT tyramide amplification kit (NEL700001KT) and streptavidin conjugated Alexa 647 from Invitrogen (1:80 dilution). For p27 and AR staining, p27 (1:100 dilution and AR (1:30 dilution) antibodies were incubated overnight at 40 C followed by incubation at RT for 1 h with subsequent staining by goat anti-mouse IgG1 Alexa 555-conjugated (Invitrogen, 1:100 dilution, for detection of p27) and anti-rabbit IgG Alexa 488-conjugated (Invitrogen, 1:80 dilution). Percentage of p27+, AR+, ER+ cells was estimated by counting 500-1000 cells/sample. Nuclear staining with DAPI and multiple fluorescence images from each section were acquired with 40× plan apo objective, following procedure described above.

Culture of Tissue Slices

Normal human breast tissues were collected from reduction mammoplasties, transported in ice-cold DMEM-F12 medium, and processed within 24 hrs. For organ cultures, thin (˜1 mm thick) slices of tissue were cut from epithelium-enriched areas and cultured for 8 days in 6-well plates using co-culture inserts to optimize the tissue/medium contact surface and changing medium (2 ml/well) every 24 hrs. The M87A medium previously optimized for human primary mammary epithelial cultures was used [see, Bloushtain-Qimron, et al. (2008) supra; Garbe, J. C., et al. (2009). Cancer Res 69, 7557-7568]. Inhibitors used included cyclopamine (Selleck Chemicals, cat #S1146)—inhibitor of Smo receptor of Hh ligands, LY2109761 (Eli Lilly)—inhibitor of TGFBR kinases, celecoxib (LKT laboratories, cat #C1644)—inhibitor of Cox2, 2-5dideoxyadenosine (Enzo Life Sciences, cat #BML-CN110-005)—adenylate cyclase inhibitor, tyrphostin AG1478 (Cayman Chemicals, cat #10010244)—EGFR inhibitor, XAV939 (Tocris Bioscience, cat #3748)—Tankyrase (TNKS) inhibitor—antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin, picropodophylotoxin (Tocris Bioscience, cat #2956)—IGFR inhibitor Stock solutions (1,000×) were prepared in DMSO. Final drug concentrations were as follows: cyclopamine—10 μM, LY2109761—500 nM, celecoxib—100 μM, 2-5dideoxyadenosine—100 μM, AG1478—10 μM, XAV939—1 μM and Picropodophylotoxin—0.5 μM. Following 8 days of culture, labeled tissue slices were pulse with bromo-deoxy-uridine (30 μM final concentration) for 5 hrs before fixing the tissue in buffered formalin at room temperature for 24 hrs followed by embedding in paraffin. Experiments were performed in triplicates using tissue from different regions of the same breast, uncultured tissue and tissue cultured without any drugs as controls. To experimentally reproduce hormone levels in follicular and luteal phase of the menstrual cycle and in mid-pregnancy, the following was used: 0.5 μM of estradiol for 8 days to mimic follicular phase; 1.2 nM of estradiol for 2 days (representing ovulation) followed by 0.7 nM of estradiol and 50 nM of progesterone for 6 days to mimic luteal phase; and a combination of 250 nM estradiol, 600 nM progesterone, 600 ng/mL prolactin, and 10 IU/mL HCG for 8 days to mimic pregnancy in the normal breast.

PCA Analysis and Plot

Unsupervised principle component analysis (PCA) was applied using R package ‘pcurve’ to gene expression profiles of different cell types from parous and nulliparous tissues. The mean of each sample was centered to zero before PCA analysis. Genes were the feature variables and samples were projected to the principle components. OpenGL was used to plot PCA results by projecting each sample to the first three principal components. Using the projected value on the largest 3 principal component as the Euclidean coordinates for each individual, paired Euclidean distance between nulliparous and parous individuals for each cell type was calculated. The distance is a global measurement of the difference between individuals. It indicated, for example, that the gene expression of CD44⁺ cells changed the most, as it has the most significant distance between nulliparous and parous samples.

Rat Gene Expression Data Analysis and Comparison with Human

Previously published gene expression data from virgin and parous rats was reanalyzed using four (WistarFurth, Copenhagen, Fischer 344, and Lewis) inbred strains of rats [Blakely, C. M., et al. (2006). Cancer Res 66, 6421-6431]. The raw data (generated using RG_U34A array) was obtained online and normalized by RMA using default parameters followed by the selection of differentially expressed genes using SAM (significance analysis of microarray) algorithm [Tusher, et al. (2001) Proc Natl Acad Sci USA 98, 5116-5121]. Differentially expressed genes for each strain was called using p value cutoff 0.05 and the union of these was used defined as “rat differential gene list”. Genes that appeared in both up and down union groups were excluded. Only genes that had homologues in both species were used for comparisons.

Supervised Principal Component Analysis with Randomized Input

Supervised principal component analysis (SPCA) was used for selection of a subset of genes with prognostic value from differentially expressed genes [Tibshirani, R., et al. (2004). Bioinformatics 20:3034-3044]. The training (Wang's) cohort [Wang, Y., et al. (2005) Lancet 365, 671-679] was randomly split after appropriate filtering of patients into training set and testing set of the same size (the same number of individual patients). Traditional PCA uses all genes to identify principal components in an unsupervised way. However, the 1^(st) principal component of unsupervised PCA might not be the projection direction of interested. SPCA in this study finds the principal components using only genes correlated with survival (ex, log rank test p value 0.05 as cutoff using univariate cox regression). The 1st principal component was used to predict the survival outcome. The correlation between a gene and the predicted outcome was used as the importance score to rank genes of importance. Cross-validation was applied to determine cut-off for significance. Genes with importance score higher than this cut-off formed the gene signature. For each random split configuration, a parity signature was obtained using SPCA. To get a robust gene signature, Wang's data was randomly split into training and testing sets 1,000 times and a signature for each configuration was obtained. It was argued that the genes that significantly contribute to breast cancer progression should appear in signatures multiple times more than randomly expected. Those genes whose frequency appearing in signature 5 times higher than random background were chosen as the final parity gene signature.

Prognostic Signature

3,515 genes were identified that were differentially expressed after pregnancy in CD44+ cells at p value cut-off 0.05 using SageExpress pipeline [Wu, Z. J., et al. (2010). Genome Res 20, 1730-1739]. Pregnancy resulted in multifaceted alterations of the mRNA expression levels in cells. Applying univariate Cox regression, 1899 genes were identified to have significant (log rank p value <0.05) correlation with survival in Wang's cohort, among which 441 genes were shown to be differentially expressed after pregnancy (p value <1.75c-10 using hypergeometric distribution for significance test). Those results suggested that the alterations of pregnancy on cell factory are likely associated with carcinogenesis and cancer progression.

In order to elucidate the parity-induced differential genes that were not only expressed together but also correlated with survival (parity-induced breast cancer signature), supervised principal component analysis described above was applied. Simply using univariate cox regression to identify genes correlated with breast cancer as the parity-induced breast cancer signature has the following drawbacks. First, univariate analysis excludes the contributions of other covariates (genes). Thus significant genes in univariate analysis might not be significant when considering other covariates. Second, gene expression often changes in a coherent way such that genes that are functionally related in one or several pathways often show strong correlation in expression levels, which is not captured by univariate analysis. Parity-induced breast cancer signature was obtained using SPCA on up and down genes after pregnancy separately. Wang's cohort was used as the training set and the signatures were validated in three other widely used breast cancer cohorts (NKI, GSE7390 (Transbig), GSE2990 (Tamoxifen) [Desmedt, C., et al. (2007). Clin Cancer Res 13, 3207-3214; Sotiriou, C., et al. (2006) J Natl Cancer Inst 98, 262-272; van de Vijver, M. J et al. (2002) N Engl J Med 347, 1999-2009]. K-mean clustering (k=2) of these signatures separated patients into two groups with significant survival difference.

Norwegian Cohort

GSE18672 cohort [Haakensen, V. D., et al. (2011a) BMC Cancer 11, 332; Haakensen, V. D., et al. (2011b). BMC medical genomics 4, 77] was used to validate the expression patterns of parity-related genes identified in this study. The following criteria were applied for sample selection from this cohort in order to match the samples used in this study: for nulliparous samples—pre-menopausal and age<40; for parous samples—pre-menopausal, number of parity with live birth=2, age<40, age at 1st birth<30. The following procedures were taken to preprocess the public data cohort GSE18672: 1—Missing value estimation using local least squares (R package pacMethods: llsimpute), 2—All genes were centered to zero followed by a loess normalization (R package affy: normalize.loess).

Statistical Analyses

The differences between the percentage of p27+ and Ki67+ cells in the samples from nulliparous and parous women were analyzed by Fisher exact test. The differences between high and low-density samples were analyzed by binomial test. P value of overlap between two groups was obtained by statistical test on hypergeometric distribution. The differences between the percentages of p27+ in the tissue slices experiments were analyzed by t-test, and the differences in BrdU+ cells were analyzed by Fisher exact test.

Kappa Statistics

Kappa statistics are a statistical measure of inter-rater agreement [Cohen, J. (1960). Educat Psych Meas 20, 37-46]. The input for kappa involves a couple of raters or learners, which classify a set of objects into categories. Here, it was used to compare lists of differentially expressed genes for their congruency. Hierarchical clustering of signaling pathways significantly down or upregulated in the four cell types was performed. Distance between two enrichments was assessed using the kappa statistics. Similar to the design in previous publications [Bessarabova, M., et al. (2011) Cancer Res 71, 3471-3481; Huang da, W., et al. (2007) Genome Biol 8, R183; Shi, W., et al. (2010) Pharmacogenomics J 10, 310-323], the value of 1 was assigned to a map if it was significant for an experiment and the value of 0 if the significant enrichment was not observed. Pathways determined to have significant enrichment are referred to herein as “statistically significant pathways.” Kappa value was calculated as

${\kappa = \frac{{\Pr(a)} - {\Pr(e)}}{1 - {\Pr(e)}}},$ where Pr(a) is the relative observed agreement among two enrichments, and Pr(e) is the hypothetical probability of chance agreement, using the observed data to calculate the probabilities of randomly calling maps significant in each experiment. As the higher values of kappa mean better agreement between enrichments and the maximal possible value of kappa is 1, the value (1-κ) was used as a distance between two experiments. Average linkage was used to construct cluster dendrogram depicted in FIG. 10 .

Generation of SAGEseq, MSDKseq, and ChIPseq Libraries

Detailed protocols for cell purification and the generation of SAGEseq (Serial Analysis of Gene Expression applied to high-throughput sequencing) [Genome Res. 2010 December; 20(12):1730-9. Epub 2010 Nov. 2., Proc Natl Acad Sci USA. 2012 Feb. 21; 109(8):2820-4. Epub 2010 Nov. 22. (http://research4 dfci.harvard.edu/polyaklab/protocols_linkpage.php)], MSDKseq (Methylation-Specific Digital Karyotyping [Hu, M., et al. (2005) Nat Genet 37, 899-905], and ChlPseq (Chromatin Immunoprecipitation applied to high-throughput sequencing) [Maruyama, R. et al. (2011) PLoS genetics 7, e1001369] libraries are posted on the web-site (http://research4.dfci.harvard.edu/polyaklab/protocols_linkpage.php). Genomic data were analyzed as described before [Kowalczyk, A., et al. (2011) J Comput Biol 18, 391-400; Maruyama, R., et al. (2011) supra; Wu, Z. J., et al. (2010) Genome Res 20, 1730-1739].

Integrated View of ChlPseq, SAGEseq, and MSDKseq Data

Differentially Methylated Regions across parity groups were identified using the Poisson margin test [Kowalczyk, A., et al. (2011) supra]. Genes were ordered as a spectrum going from higher in parous to higher in nulliparous, based on p-values. Fisher exact tests were performed using sum of target gene numbers in 1,000-gene window and total count of target genes outside of the window, testing the enrichment of targets inside the windows.

Protein Interactome Analyses

In order to determine overall activation of specific biological functions due to parity in the cell types analyzed, pathway enrichment, network, and protein interactome analyses were performed using the MetaCore platform as described in Bessarabova et al., supra; Ekins, S., et al. (2006) Book Chapter in In High Content Screening (Humana Press), pp. 319-350; Nikolsky, Y., et al. (2009) Methods Mol Biol 563, 177-196).

Nurses' Health Study Data

The Nurses' Health Study (NHS) is a prospective cohort study established in 1976 when 121,700 female registered nurses from across the United States, aged 30-55 years, completed a mailed questionnaire on factors that influence women's health. Follow-up questionnaires have since been sent out every two years to the NHS participants to update exposure information and ascertain non-fatal incident diseases. Incident breast cancer was ascertained by the biennial questionnaire to study participants. For any report of breast cancer, written permission was obtained from participants to review their medical records to confirm the diagnosis and to classify cancers as in situ or invasive, by histological type, size and presence or absence of metastases. Overall, 99% of self-reported breast cancers have been confirmed. To identify breast cancer cases in non-respondents who died, death certificates and medical records for all deceased participants were obtained to ascertain cause of death. This study was approved by the Human Subjects Committee at Brigham and Women's Hospital in Boston, Mass. Breast cancer cases were followed from the date of diagnosis until Jan. 1, 2008 or death, whichever came first. Ascertainment of deaths included reporting by next of kin or postal authorities or searching the National Death Index.

Approximately 98% of deaths in the NHS have been identified by these methods. Cause of death was ascertained from death certificates and physician review of medical records. Information on estrogen receptor (ER) status was extracted from the medical record and pathology reports. If data were missing for ER status, scoring from immunohistochemical staining for ER on 5 μm paraffin sections cut from tissue microarray (TMA) blocks was used [Tamimi, R. M., et al. (2008) Breast Cancer Res 10, R67]. There were 8,055 women with invasive breast cancer diagnosed after return of the 1976 baseline questionnaire through 2006 questionnaire. One woman was excluded due to missing information on parity. Thus, our final analysis included 8,054 women with invasive breast cancer and information on parity. Survival curves were estimated by the Kaplan-Meier method and statistical significance was assessed with the log-rank test. Multivariate cox proportional hazards regression models were used to evaluate the relationship between parity and breast cancer-specific mortality after adjusting for age at diagnosis, aspirin use, date of diagnosis, disease stage, grade, radiation treatment, chemotherapy and hormonal treatment. All analyses were performed using SAS version 9.1. All statistical tests were two sided and P<0.05 was considered statistically significant.

Accession Numbers

Raw data files and methodological details have been submitted to GEO with accession number GSE32017.

Example 2: Parity-Related Differences in Gene Expression in Multiple Cell Types

This example demonstrates the effect parity has on the cellular composition of normal human breast.

To investigate if parity affects the cellular composition of normal human breast, first breast epithelial cells from nulliparous and parous women were analyzed by FACS (fluorescence-activated cell sorting) for cell surface markers previously associated with luminal epithelial (CD24), myoepithelial (CD10), and progenitor features (lin−/CD44+) [Bloushtain-Qimron et al., supra; Mani et al. (2008) Cell 16; 133(4):704-15; Shipitsin et al., (2007) Cancer Cell 11, 259-273]. It was found that CD24+, CD44+, and CD10+ cells represent three distinct cell populations with minimal overlap both in nulliparous and parous tissues. FIG. 1 shows the FACS plot for CD24+ versus CD44+ cells, and it could be seen that there were very few cells that stained positive for both markers. (FIG. 1 ). Multicolor immunofluorescence analyses was also performed for these three cell surface markers alone or in combinations, and additional known markers for a subset of luminal (GATA3) and myoepithelial (SMA) cells, which further confirmed the identity of the cells. Subsequent FACS analysis of multiple tissue samples showed significant differences in the relative frequency of CD44+ and CD24+ cells between parous and nulliparous samples, whereas the relative frequency of CD10+ cells was essentially the same (FIG. 2 ). The changes in the relative frequency of CD24+ and CD44+ cells could potentially have been due to the increased number of lobulo-alveolar structures observed in parous women.

To investigate parity-related differences in global gene expression profiles, immuno-magnetic bead purified (Bloushtain-Qimron et al., 2008 supra; Shipitsin et al., 2007, supra) CD24+, CD10+, and CD44+ cells (captured sequentially, thus, CD44+ fraction was CD24-CD10-CD44+, but the CD24+ fraction may have contained some CD24+ CD44+ cells), and fibroblast-enriched stroma from multiple nulliparous and parous women were analyzed using SAGEseq (Serial Analysis of Gene Expression applied to high-throughput sequencing). To minimize variability among individuals unrelated to parity status, women were closely matched for age, the number of pregnancies, time at first and since last pregnancy, and ethnicity. The analysis is summarized in Table 3, below, which shows the tissue code, age, parity, ethnicity, and menopausal status of the patient, type of surgery for tissue acquisition, mammographic breast density, cell type analyzed, raw and aligned tag/read counts for Sageseq, MSDKseq, and ChlPseq data below, in which an “x” in qRT-PCR, qMSP, FACS, and IF/IHC (immunofluorescence/immunohistochemistry) columns indicate the use of that sample for the analysis.

The expression of known cell type-specific genes (e.g., luminal cell markers KRT8 and MUC1, myoepithelial cell markers ACTG2 and CNN1, and progenitor cell markers ZEB2 and TWIST1) was consistently observed in each of the three respective epithelial cell types both from nulliparous and parous samples based on SAGEseq confirming the purity and identity of the cells. Comparison of each cell type between nulliparous and parous samples revealed the most pronounced differences in CD44+ cells (FIG. 3 and Table 4, below), where the numbers of significantly (p<0.05) differentially expressed genes and the fold differences were the largest between groups. Tables 4, 5, 6 and 7 list the differentially expressed genes in CD44+, CD24+, CD10+, and stromal breast epithelial cells, respectively, from normal human reduction mammoplasty samples of nulliparous (NP) and parous (P) women. The tables list gene symbols, log transformed normalized tag counts in CD44+, CD24+, CD10+ or stromal breast epithelial cells from nulliparous (columns 2-4) and parous (columns 5-7) with fold change between nulliparous and parous samples (based on average of actual normalized tag count of the three tissues), p-value (<0.05) and gene description.

The degrees of differences were smaller and similar in CD10+ and CD24+ cells, whereas stromal fibroblasts had the fewest differentially expressed genes (Tables 5 and 6). Further examination of parity-related differences in expression patterns using principal component analysis (PCA) confirmed that CD24+ and CD10+ cells and fibroblasts from nulliparous and parous women were similar, whereas CD44+ cells formed very distinct nulliparous and parous clusters (FIGS. 4A and 4B). Interestingly, CD44+ cells from nulliparous women were more similar to CD10+ cells, whereas from parous cases they were more similar to CD24+ cells. This implied a shift from a more basal to a more luminal gene expression pattern in CD44+ cells after parity (FIG. 5 ).

TABLE 3 Parity-related Differences in Global Gene Expression Profiles Meno- Type SAGE-Seq MSDK-Seq ChIP-Seq K27 Eth- pausal of Breast Cell raw alligned raw alligned raw alligned Tissue Age Parity nicity status surgery density type tag tag tag tag tag tag N33 19 PAR-0 AA Pre Rdx CD24+ 9,618,916 6,401,701 10,777,438 6,554,664 CD44+ 4,147,642 2,356,179 stroma 9,548,881 7,188,232 N34 27 UK AA Pre Rdx CD24+ CD44+ 8,945,148 5,668,737 N35 18 PAR-0 AA Pre Rdx CD24+ 13,522,703 9,518,916 7,907,066 5,669,764 CD44+ 3,981,235 2,507,858 CD10+ 23,303,110 18,244,367 stroma 12,435,941 9,436,721 N37 24 PAR-2 AA Pre Rdx CD24+ 4,861,324 3,295,244 7,269,319 5,180,418 CD44+ 4,170,428 2,696,351 8,657,890 7,048,887 stroma 4,874,878 3,247,011 N39 32 PAR-3 CU Pre Rdx CD24+ 4,189,542 2,831,627 8,556,003 6,928,902 CD44+ 4,278,041 2,820,466 8,259,680 5,878,487 CD10+ 20,005,642 14,772,311 stroma 8,726,273 6,737,622 N40 29 PAR-2 AA Pre Rdx CD24+ 3,540,368 2,311,370 7,491,800 6,277,412 CD44+ 3,979,209 2,463,398 8,335,235 6,910,263 CD10+ 16,842,503 10,224,177 stroma 4,131,771 2,899,771 N43 28 PAR-0 AA Pre Rdx CD24+ 11,645,900 8,062,235 CD44+ 13026527 9835625 CD10+ 23,754,619 16,664,431 N47 21 UK AA Pre Rdx CD24+ 2,983,207 1,933,928 CD44+ 1,824,933 1,137,819 N48 26 PAR-0 CU Pre Rdx CD24+ 1,800,069 1,098,424 14,849,010 8,402,630 CD44+ 1,045,874 695,300 10,935,565 4,166,534 CD10+ 23100428 15163719 N58 23 PAR-0 AA Pre Rdx CD24+ 9,720,068 6,197,805 CD44+ 11,007,864 7,066,583 stroma 11,466,462 8,276,113 N66 21 PAR-1 AA Pre Rdx CD24+ 17,669,447 10,633,724 CD44+ 115,374,101 59,596,544 N74 20 PAR-0 AA Pre Rdx CD24+ 16,760,143 9,086,702 CD44+ 125,461,312 66,593,764 N123 31 PAR-2 AA Pre Rdx CD10+ 25,194,642 17,423,893 N27 23 PAR-0 AA Pre Rdx N28 35 PAR-2 AA Pre Rdx N29 26 PAR-0 CU Pre Rdx N31 31 PAR-2 AA Pre Rdx N38 32 PAR-0 CU Pre Rdx N42 17 PAR-0 CU Pre Rdx N44 21 PAR-0 CU Pre Rdx N53 41 PAR-2 AA Pre Rdx N55 22 PAR-0 CU Pre Rdx N57 27 PAR-0 CU Pre Rdx N61 20 PAR-1 AA Pre Rdx N63 21 PAR-0 CU Pre Rdx N65 55 PAR-4 AA Rdx N69 27 PAR-0 CU Pre Rdx N71 29 PAR-1 AA Pre Rdx N72 23 PAR-2 AA Pre Rdx N78 23 PAR-1 AA Pre Rdx N84 29 PAR AA Pre Rdx N85 25 PAR-0 CU Pre Rdx N91 23 PAR-0 HP Pre Rdx N93 29 PAR ? Pre Rdx N95 34 PAR-2 CU Pre Rdx N99 29 PAR-2 ? Pre Rdx N102 16 PAR-0 CU Pre Rdx N103 17 PAR-0 AA Pre Rdx N104 17 PAR-0 AA Pre Rdx N106 20 PAR-0 CU Pre Rdx N108 27 PAR-3 AA Pre Rdx N109 36 PAR-2 AS Pre Rdx N111 27 PAR-2 HP Pre Rdx N112 26 PAR-2 AA Pre Rdx N113 23 PAR-1 CU Pre Rdx N114 19 PAR-0 CU Pre Rdx N115 27 PAR-2 AA Pre Rdx N116 22 PAR-2 AA Pre Rdx N117 22 PAR-0 CU Pre Rdx N121 39 PAR-2 CU Pre Rdx N135 53 PAR-2 CU Rdx N136 20 PAR-0 CU Pre Rdx N141 21 UK CU Pre Rdx N165 24 PAR-1 CU Pre Rdx N166 28 PAR-2 AA Pre Rdx N175 20 PAR-0 CU Pre Rdx N178 21 PAR-0 cu Pre Rdx 275L 52 PAR-4 AA Post Rdx 269R 53 PAR ? Post Rdx 186L 62 PAR-2 AA Post Rdx 219L 73 PAR-3 CU Post Rdx 272 60 PAR-1 CU Post Rdx 227R 55 PAR-2 ? Post prophy- lactic 188 54 PAR-2 AA Post prophy- lactic 204R 56 PAR-2 CU Post prophy- lactic 213L 57 PAR-3 CU Post prophy- lactic 241 57 PAR-5 CU Post prophy- lactic 190 49 PAR-0 CU Post prophy- lactic 207R 52 PAR-0 CU Post prophy- lactic 221 L 54 PAR-0 CU Post prophy- lactic 212 60 PAR-0 AA Post prophy- lactic 288 41 PAR-0 CU Post prophy- lactic 307 61 PAR-0 CU Post prophy- lactic 313 63 PAR-0 CU Post prophy- lactic MDB11 52 PAR-2 CU biopsy High MDB17 61 PAR-2 CU Post biopsy High MDB27 49 PAR-1 CU Pre biopsy High MDB29 PAR-1 ? biopsy Low MDB32 37 PAR-2 AS Pre biopsy High MDB34 PAR-2 ? biopsy Low MDB35 31 PAR-5 CU Pre biopsy High MDB48 35 PAR-2 CU Pre biopsy Low MDB51 PAR-2 ? biopsy High MDB56 40 PAR-2 CU Pre biopsy Low MDB59 PAR-2 9 biopsy High MDS19 PAR-2 9 slice Low MDS35 PAR-2 9 slice Low MDS48 35 PAR-3 CU Pre slice High MDS52 PAR-3 9 slice Low MDS60 48 PAR-2 CU Pre slice High MDS61 PAR-2 9 slice Low MDS71 43 PAR-2 CU Pre slice High MDS74 PAR-2 9 slice Low MDS8 34 PAR-2 CU Pre slice High qRT- Tissue PCR qMSP FACS IF/IHC CULT Notes N33 x x x N34 N35 x x x N37 x x N39 x x N40 x x N43 x x N47 N48 x x N58 x x N66 N74 x N123 x x N27 x N28 x N29 x N31 x N38 x N42 x x x N44 x x x N53 x N55 x x N57 x N61 x x N63 x N65 x N69 x N71 x N72 x x N78 x N84 x N85 x x x N91 x x N93 x N95 x x N99 x N102 x N103 x N104 x x N106 x x N108 x x N109 x N111 x x x N112 x N113 x x N114 x x N115 x x x x N116 x x N117 x x N121 x x N135 x N136 x N141 x N165 x N166 x N175 x N178 x 275L x 269R x 186L x 30 Atypical LH33 Usual DH35 Papilloma40 Prolif. fibrocystic changes61 Mammoplasty 219L x 272 x 227R x 188 x 45 Non-prolif. fibrocystic or other changes47 Inflammation 204R x 213L x 30 Atypical LH 241 x left breast (left total mastectomy): no invasive carcinoma seen, marked atypical lobular hyperplasia approaching criteria for lobular carcinoma in situ and focal atypical ductal hyperplasia, residual intraductal papilloma with biopsy site changes, multiple micropapillomas, columnar cell hyperplasia with cytologic atypia, and fibrocystic changes including usual ductal hyperplasia, ~ microcalcifications identified in upper outer, upper inner, lower outer and lower inner quadrants.; right breast not sampled: 31 atypical dh 30 atypical lh 35 papilloma 33 usual dh; no contralateral be and this breast was totally removed and has marked alh 190 x 2. LEFT BREAST (TOTAL MASTECTOMY): FOCAL ATYPICAL LOBULAR HYPERPLASIA IDENTIFIED. RADIAL SCAR AND FOCAL COLLAGENOUS SPHERULOSIS. FIBROCYSTIC CHANGES, INCLUDING DUCT ECTASIA AND APOCRINE METAPLASIA. MICROCALCIFICATIONS SEEN WITHIN BENIGN GLANDS. ~ NEGATIVE FOR TUMOR. 3. RIGHT BREAST (TOTAL MASTECTOMY): Ductal carcinoma in situ (DCIS). 1.3 cm grossly; the largest single focus of DCIS is 0.3 cm. M160; 22 DCIS 230 Atypical LH43 Radial scar62 Collagenous Spherulosis 207R x 221 L x LEFT BREAST: EXTENSIVE ATYPICAL LOBULAR HYPERPLASIA WITH FIBROCYSTIC CHANGES, COLUMNAR CELL CHANGE, SCLEROSING ADENOSIS, AND MICROCALCIFICATIONS SEEN IN ASSOCIATION WITH BENIGN BREAST PARENCHYMA. NEGATIVE FOR INVASIVE CARCINOMA; RIGHT BREAST Infiltrating mammary carcinoma with ductal and lobular features; 08 Inv. mammary CA45 Non-prolif. fibrocystic or other changes 212 x 45 Non-prolif. fibrocystic or other changes 288 x 307 x 313 x MDB11 x BRCA2, PHx BC MDB17 x DCIS, FHx Mother BC 45 MDB27 x BRCA2, PHx bilateral oophorectomy MDB29 x MDB32 x BRCA1, BC MDB34 x MDB35 x BRCA2 MDB48 x BRCA1 MDB51 x MDB56 x BRCA1, R breast ca, L SSM, BPO MDB59 x MDS19 x MDS35 x MDS48 x BRCA2 MDS52 x MDS60 x BRCA2, L DCIS MDS61 x MDS71 x BRCA1 MDS74 x MDS8 x strong FHx: 7/9 women BC Abbreviations: “AA”: African American; “CU”: Caucasian; “HP”: Hispanic; “AS”: Asian; “?”: unknown; “Rdxn”: reduction; “Pre”: premenopausal; “Post”: postmenopausal. PAR-0 means 0 live births, PAR-1 means 1 live birth, PAR-2 means 2 live births, etc.; “UK”, “?” or empty field means unknown.

TABLE 4 Differentially Expressed Genes in CD44+ Breast Epithelial Cells Nulliparous (NP) Samples Parous (P) Samples Pseudo CD44+ CD44+ CD44+ CD44+ CD44+ CD44+ fold Gene Symbol N48 N58 N43 N37 N39 N40 change P value Gene description Higher Expression in Nulliparous HBB 8.647 16.805 13.823 7.618 6.519 6.320 −158.005 0.0081376 hemoglobin, beta SEC61B 0.648 8.071 7.682 0.648 0.648 0.648 −131.001 0.0204697 Sec61 beta subunit HBA1 4.972 13.737 10.850 4.529 3.871 4.389 −88.112 0.0150652 hemoglobin, alpha 1 KRTAP4-12 0.648 7.519 7.072 0.648 0.648 0.648 −85.830 0.0222555 keratin associated protein 4-12 COX17 0.648 7.215 6.821 0.648 0.648 0.648 −72.130 0.0232128 COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) NCRNA00188 7.097 11.959 11.406 5.245 4.754 5.237 −71.960 0.0055269 non-protein coding RNA 188 RPS29 7.658 12.828 12.402 4.981 5.508 6.679 −70.970 0.0066430 ribosomal protein S29 RPL27A 8.098 12.704 12.477 5.652 5.732 6.635 −67.139 0.0053321 ribosomal protein L27a COL3A1 15.562 12.000 11.854 5.787 7.350 8.068 −67.080 0.0013099 collagen, type III, alpha 1 ERH 3.422 8.682 7.643 2.625 1.648 1.648 −63.771 0.0099352 enhancer of rudimentary homolog (Drosophila) SRP19 0.648 6.638 6.666 0.648 0.648 0.648 −63.530 0.0242693 signal recognition particle 19 kDa MTND3 9.246 13.456 13.535 6.682 7.613 6.556 −60.630 0.0044010 No description LOC728640 3.194 6.597 6.494 0.648 0.648 0.648 −57.528 0.0028697 No description CD9 6.906 10.132 9.475 4.023 3.659 3.303 −56.360 0.0010860 CD9 molecule ITM2A 10.733 11.707 11.583 4.951 5.344 6.820 −55.036 0.0001563 integral membrane protein 2A FAM10A4 4.972 9.120 9.050 3.351 2.353 3.043 −54.534 0.0054458 No description HNRNPA1 3.619 8.990 7.992 3.278 2.233 2.233 −52.447 0.0136315 heterogeneous nuclear ribonucleoprotein A1 TRMT5 5.235 9.979 9.956 2.970 2.970 4.327 −50.282 0.0073147 TRM5tRNA methyltransferase 5 homolog (S. cerevisiae) TXN 3.619 11.152 10.795 5.256 3.559 5.147 −50.124 0.0435317 thioredoxin TUBA1B 6.689 11.666 11.390 5.660 5.914 5.749 −49.875 0.0139955 tubulin, alpha 1b YBX1 6.196 10.489 10.347 4.869 4.697 4.323 −49.183 0.0082811 Y box binding protein 1 MYEOV2 0.648 7.122 6.202 0.648 0.648 0.648 −46.973 0.0245799 myeloma overexpressed 2 NDUFB4 7.531 9.476 9.845 4.372 3.284 2.370 −44.414 0.0005064 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15 kDa LUM 9.317 13.167 10.563 5.134 4.504 6.235 −43.086 0.0012558 lumican RAB6C 0.648 7.611 6.395 2.202 0.648 0.648 −42.502 0.0368516 RAB6C, member RAS oncogene family TMEM11 3.860 7.125 6.054 0.648 0.648 0.648 −42.405 0.0011387 transmembrane protein 11 LOC653566 5.739 8.703 8.889 3.351 0.648 3.351 −40.858 0.0029397 No description UBE2NL 6.312 10.364 5.977 0.648 3.284 3.351 −40.180 0.0065709 ubiquitin-conjugating enzyme E2N-like GPR89A 0.648 6.549 5.956 0.648 0.648 0.648 −39.615 0.0258277 G protein-coupled receptor 89A COL1A1 14.250 12.168 11.083 5.822 7.572 8.793 −38.367 0.0029757 collagen, type I, alpha 1 NUDT4P1 3.860 8.958 7.461 2.202 0.648 3.043 −38.311 0.0087220 nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1 ISCA1 0.648 6.177 5.899 0.648 0.648 0.648 −38.081 0.0267386 iron-sulfur cluster assembly 1 homolog (S. cerevisiae) HSPA2 5.870 6.981 6.117 2.714 0.648 0.648 −37.314 0.0006194 heat shock 70 kDa protein 2 PCBP1 8.603 11.285 11.391 6.087 5.763 6.197 −36.600 0.0025071 poly(rC) binding protein 1 KRT10 0.648 5.870 5.761 0.648 0.648 0.648 −34.605 0.0279262 keratin 10 INS-IGF2 10.308 9.204 9.134 4.021 4.043 6.006 −34.586 0.0007324 No description ANXA3 3.194 5.754 6.378 0.648 0.648 0.648 −34.443 0.0027900 annexin A3 RPL7 10.636 13.028 12.983 7.244 7.929 7.722 −34.262 0.0012738 ribosomal protein L7 KLK3 5.739 5.521 5.754 0.648 0.648 0.648 −34.075 0.0000738 kallikrein-related peptidase 3 SHFM1 1.648 7.890 6.701 1.648 2.739 1.648 −33.198 0.0371744 split hand/foot malformation (ectrodactyly) type 1 SEP2 10.248 10.425 10.374 6.570 5.325 5.140 −33.102 0.0001972 septin 2 RPL26 8.606 12.693 12.085 6.947 7.056 7.316 −32.643 0.0092225 ribosomal protein L26 GABARAP 7.394 10.012 10.092 5.102 3.499 3.929 −31.765 0.0015040 GABA(A) receptor-associated protein BUD31 3.194 8.066 7.993 3.081 2.353 2.370 −31.676 0.0183061 BUD31 homolog (S. cerevisiae) UBAC1 3.194 6.126 5.544 0.648 0.648 0.648 −29.759 0.0027088 UBA domain containing 1 ALKBH5 9.928 11.367 11.055 6.503 5.518 5.311 −29.126 0.0002513 alkB, alkylation repair homolog 5 (E. coli)) RPL37 10.581 13.131 13.029 7.164 8.072 8.275 −28.974 0.0022485 ribosomal protein L37 PCNP 2.233 7.899 7.875 2.233 2.233 3.054 −28.731 0.0325213 PEST proteolytic signal containing nuclear protein RCN2 5.972 7.462 7.136 2.625 1.648 1.648 −28.583 0.0002693 reticulocalbin 2, EF-hand calcium binding domain TPT1 9.340 12.721 12.261 6.968 7.443 7.857 −28.210 0.0062811 tumor protein, translationally-controlled 1 RAB32 5.503 7.826 8.100 3.278 3.043 2.233 −27.537 0.0026458 RAB32, member RAS oncogene family COX6A1 2.233 8.695 7.823 3.278 2.233 3.054 −27.262 0.0416541 cytochrome c oxidase subunit Vla polypeptide 1 SLC38A5 6.689 8.619 9.360 3.797 4.508 3.859 −27.100 0.0026139 solute carrier family 38, member 5 PMAIP1 5.104 7.419 7.489 1.648 2.739 1.648 −26.916 0.0014270 phorbol-12-myristate-13-acetate-induced protein 1 MYL9 9.593 10.372 8.270 4.492 5.654 3.859 −26.330 0.0009730 myosin, light chain 9, regulatory GLT8D2 6.948 7.589 6.972 2.233 2.233 4.481 −26.267 0.0020842 glycosyltransferase 8 domain containing 2 TCN2 6.202 5.544 5.359 0.648 0.648 2.370 −26.181 0.0007414 transcobalamin II TMEM14C 6.734 8.339 7.435 3.326 2.739 2.752 −25.679 0.0003414 transmembrane protein 14C PPP1CA 5.861 8.464 8.699 4.017 2.648 2.648 −25.658 0.0027629 protein phosphatase 1, catalytic subunit, alpha isozyme TMEM93 4.008 7.416 7.691 3.023 1.648 1.648 −25.421 0.0071733 transmembrane protein 93 MTCO1 12.874 13.692 13.863 9.044 9.612 7.985 −25.073 0.0004704 No description GADD45A 6.069 9.577 8.737 2.648 4.097 4.647 −24.932 0.0058582 growth arrest and DNA-damage-inducible, alpha ACTG1 13.979 14.085 13.590 9.279 9.936 8.967 −24.639 0.0001473 actin, gamma 1 DNTTIP1 1.648 6.232 6.244 1.648 1.648 1.648 −23.986 0.0317369 deoxynucleotidyltransferase, terminal, interacting protein 1 PENK 7.941 7.204 2.841 2.648 2.648 2.648 −23.518 0.0260981 proenkephalin KIAA0114 1.648 7.055 7.571 3.023 1.648 1.648 −23.390 0.0402596 KIAA0114 AZGP1 5.821 7.886 8.813 2.951 4.265 2.233 −23.389 0.0040939 alpha-2-glycoprotein 1, zinc-binding DAP 6.777 9.285 8.177 4.678 3.648 3.648 −23.077 0.0026908 death-associated protein MRPL15 0.648 6.723 5.961 2.202 0.648 0.648 −22.956 0.0431463 mitochondrial ribosomal protein L15 SNX3 3.619 8.838 8.092 3.871 3.043 3.574 −22.917 0.0277834 sorting nexin 3 SEPP1 8.967 9.118 9.243 3.838 4.618 5.019 −22.637 0.0001383 selenoprotein P, plasma, 1 MRPL44 7.257 9.680 9.785 5.018 4.508 5.297 −22.436 0.0037529 mitochondrial ribosomal protein L44 EEF1G 12.169 13.523 13.689 8.514 9.210 8.857 −22.303 0.0006104 eukaryotic translation elongation factor 1 gamma SLC2A14 8.465 6.340 6.562 4.017 1.648 3.929 −21.820 0.0061133 solute carrier family 2 (facilitated glucose transporter), member 14 ERO1L 8.074 9.537 9.526 5.117 4.600 4.013 −21.396 0.0005785 ERO1-like (S. cerevisiae) NGRN 5.552 8.281 8.108 3.718 3.852 3.303 −20.964 0.0058943 neugrin, neurite outgrowth associated C5orf13 9.154 7.541 7.609 3.233 3.233 3.233 −20.757 0.0002423 chromosome 5 open reading frame 13 ATP1B1 5.885 8.675 8.958 3.818 4.585 4.146 −20.719 0.0079636 ATPase, Na+/K+ transporting, beta 1 polypeptide YWHAE 5.645 9.950 9.172 4.775 4.800 5.290 −20.698 0.0197203 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide CHMP5 6.576 8.576 8.805 4.477 1.648 4.205 −20.689 0.0040218 chromatin modifying protein 5 PNRC1 10.505 12.324 12.179 7.958 6.663 7.685 −20.618 0.0014451 proline-rich nuclear receptor coactivator 1 TMEM66 6.512 9.520 8.515 4.151 3.508 5.008 −20.591 0.0052960 transmembrane protein 66 EEF1E1 1.648 6.003 6.178 1.648 1.648 1.648 −20.465 0.0330832 eukaryotic translation elongation factor 1 epsilon 1 COX6C 4.142 8.087 8.031 2.951 2.233 3.737 −20.391 0.0136135 cytochrome c oxidase subunit Vlc H1FX 9.181 10.411 11.038 7.775 4.838 5.939 −20.288 0.0052870 H1 histone family, member X BMS1P5 4.972 5.514 6.308 2.202 0.648 0.648 −20.022 0.0008045 BMS1 pseudogene 5 MRPL36 0.648 5.748 4.972 0.648 0.648 0.648 −20.022 0.0313778 mitochondrial ribosomal protein L36 SNRNP27 4.264 7.866 8.174 3.494 3.852 2.648 −19.997 0.0164995 small nuclear ribonucleoprotein 27 kDa (U4/U6.U5) C8orf59 3.422 7.273 7.343 3.023 2.739 1.648 −19.970 0.0162825 chromosome 8 open reading frame 59 TUBA1C 6.967 11.132 10.008 5.691 6.454 5.400 −19.937 0.0149882 tubulin, alpha 1c TMSB10 10.463 12.314 12.473 7.183 8.161 7.927 −19.867 0.0021383 thymosin beta 10 CXCL6 6.470 10.026 10.054 5.602 4.618 5.749 −19.766 0.0140343 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) SURF1 1.648 6.251 5.940 1.648 1.648 1.648 −19.583 0.0331400 surfeit 1 DERL2 2.648 7.725 7.507 3.218 2.648 3.303 −19.549 0.0442350 Der1-like domain family, member 2 ITPA 4.657 7.543 6.960 3.278 2.233 2.233 −19.237 0.0058028 inosine triphosphatase (nucleoside triphosphate pyrophosphatase) RPLP1 6.711 11.703 10.309 6.056 5.848 6.416 −19.068 0.0211289 ribosomal protein, large, P1 C7orf23 1.648 5.897 6.033 1.648 1.648 1.648 −19.014 0.0342707 chromosome 7 open reading frame 23 FBXO7 5.423 8.077 7.855 3.838 3.294 2.648 −18.884 0.0050340 F-box protein 7 C14orf147 8.217 10.423 10.475 5.864 6.170 6.288 −18.218 0.0045376 chromosome 14 open reading frame 147 FAM162A 3.422 7.320 6.924 1.648 2.739 2.752 −18.187 0.0153570 family with sequence similarity 162, member A SYPL1 4.482 9.210 9.108 4.930 4.772 5.005 −18.090 0.0484003 synaptophysin-like 1 CENPH 7.001 8.255 7.839 3.737 3.686 3.054 −17.781 0.0004433 centromere protein H MRFAP1 2.648 7.851 6.795 3.218 2.648 2.648 −17.716 0.0396808 Mof4 family associated protein 1 TUBA1A 8.428 10.140 9.793 4.529 6.006 5.014 −17.565 0.0011657 tubulin, alpha 1a KCTD9 7.090 9.444 9.585 4.954 4.581 5.451 −17.552 0.0050610 potassium channel tetramerisation domain containing 9 COX6B1 4.008 8.325 8.507 4.376 4.174 3.929 −17.530 0.0395192 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) RPS8 9.220 11.925 12.160 7.022 7.798 7.945 −17.475 0.0088794 ribosomal protein S8 CUL4B 6.848 6.936 6.356 2.951 2.233 2.233 −17.425 0.0001744 cullin 4B MTND5 8.549 11.299 10.476 6.856 6.357 5.893 −17.373 0.0050520 No description UGDH 7.690 11.658 10.444 6.380 6.178 6.327 −17.351 0.0112565 UDP-glucose 6-dehydrogenase MRPL51 0.648 6.318 6.279 2.202 0.648 0.648 −17.342 0.0431172 mitochondrial ribosomal protein L51 RBM3 8.937 10.422 10.580 6.401 6.320 5.155 −17.170 0.0016981 RNA binding motif (RNP1, RRM) protein 3 NDUFA4 5.808 8.849 8.402 4.067 4.757 4.104 −17.059 0.0103373 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9 kDa NCSTN 7.148 8.445 7.058 3.881 2.970 3.859 −17.003 0.0010180 nicastrin KRT6B 6.829 10.079 8.896 4.376 7.613 2.752 −16.869 0.0229771 keratin 6B HMGCL 5.204 3.959 4.713 0.648 0.648 0.648 −16.736 0.0004523 3-hydroxymethyl-3-methylglutaryl-CoA lyase E2F5 0.648 4.713 5.256 0.648 0.648 0.648 −16.736 0.0345099 E2F transcription factor 5, p130-binding PTP4A2 9.512 11.322 10.748 6.773 6.340 6.685 −16.723 0.0011567 protein tyrosine phosphatase type IVA, member 2 SPARC 12.921 13.011 11.241 8.708 8.558 8.963 −16.538 0.0023269 secreted protein, acidic, cysteine-rich (osteonectin) ATPIF1 6.251 7.671 7.429 3.625 3.294 3.303 −16.520 0.0010589 ATPase inhibitory factor 1 LITAF 10.529 11.665 11.017 6.839 6.973 7.032 −16.506 0.0002873 lipopolysaccharide-induced TNF factor HBP1 4.634 8.807 8.714 4.764 4.108 4.580 −16.490 0.0312482 HMG-box transcription factor 1 PPP6C 7.663 9.523 9.349 5.482 5.272 4.293 −16.468 0.0027179 protein phosphatase 6, catalytic subunit COL1A2 13.816 11.981 11.457 8.141 7.421 8.682 −16.413 0.0018049 collagen, type I, alpha 2 USMG5 6.262 9.240 8.839 4.804 5.183 3.737 −16.400 0.0095220 up-regulated during skeletal muscle growth 5 homolog (mouse) FOS 11.330 13.047 13.231 7.738 8.344 9.221 −16.117 0.0020752 FBJ murine osteosarcoma viral oncogene homolog LRRC41 10.097 11.106 10.589 6.579 6.727 6.197 −16.115 0.0002964 leucine rich repeat containing 41 LGALS3 5.322 9.705 9.129 5.120 5.050 5.407 −16.107 0.0321050 lectin, galactoside-binding, soluble, 3 BRD7P3 4.647 7.288 6.037 0.648 3.284 0.648 −16.050 0.0045737 bromodomain containing 7 pseudogene 3 VKORC1 6.347 8.151 6.648 3.625 2.648 2.648 −15.994 0.0014721 vitamin K epoxide reductase complex, subunit 1 CSTF1 4.647 5.403 6.142 0.648 2.353 0.648 −15.982 0.0016260 cleavage stimulation factor, 3′ pre-RNA, subunit 1, 50 kDa C1orf43 4.525 7.872 7.788 3.877 3.467 2.233 −15.950 0.0131088 chromosome 1 open reading frame 43 RPL27 8.900 11.804 11.213 7.308 7.147 7.222 −15.895 0.0080614 ribosomal protein L27 F3 5.936 8.691 8.283 4.026 4.701 4.007 −15.891 0.0082971 coagulation factor III (thromboplastin, tissue factor) FIGF 8.763 7.210 4.425 3.233 3.233 4.553 −15.746 0.0238977 c-fos induced growth factor (vascular endothelial growth factor D) PPP1R15A 9.690 11.015 10.841 6.209 6.767 7.039 −15.741 0.0010000 protein phosphatase 1, regulatory (inhibitor) subunit 15A PPP2R2A 5.936 8.906 8.406 4.026 4.490 4.436 −15.675 0.0087082 protein phosphatase 2, regulatory subunit B, alpha ID4 5.809 9.133 6.939 3.442 2.970 2.970 −15.661 0.0041605 Description CDKN1B 7.367 7.407 7.471 3.442 2.970 3.859 −15.612 0.0002333 cyclin-dependent kinase inhibitor 1B (p27, Kip1) RPS20 11.289 12.945 11.949 7.891 8.161 7.986 −15.602 0.0007504 ribosomal protein S20 VASP 6.741 8.742 7.454 4.273 4.784 2.648 −15.545 0.0051380 vasodilator-stimulated phosphoprotein LILRB3 6.340 8.555 8.128 4.477 4.174 2.752 −15.495 0.0042790 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 RAB13 7.177 8.862 8.599 5.093 3.233 4.007 −15.384 0.0021293 RAB13, member RAS oncogene family SC4MOL 6.873 9.429 9.263 5.489 4.791 3.701 −15.349 0.0058173 sterol-C4-methyl oxidase-like RPS18 12.062 14.408 14.030 9.707 10.357 10.104 −15.203 0.0055518 ribosomal protein S18 RPS19 7.761 12.478 11.500 7.339 7.771 7.574 −15.197 0.0297189 ribosomal protein S19 GNG11 6.911 7.182 6.392 4.972 2.987 0.648 −15.186 0.0097619 guanine nucleotide binding protein (G protein), gamma 11 DCN 11.356 13.930 12.077 8.162 8.030 8.978 −15.082 0.0030028 decorin HSP90AB1 12.747 14.232 14.095 9.664 10.274 10.180 −15.080 0.0016440 heat shock protein 90 kDa alpha (cytosolic), class B member 1 SFRS9 8.226 10.361 10.536 6.518 6.447 6.036 −15.072 0.0061633 No description MED28 4.734 7.470 7.298 1.648 2.739 3.557 −15.067 0.0069300 mediator complex subunit 28 C11orf10 10.342 10.380 10.555 7.203 6.469 6.124 −15.048 0.0004974 chromosome 11 open reading frame 10 H3F3C 8.402 10.636 9.974 6.728 5.600 5.889 −15.018 0.0043830 H3 histone, family 3C PITRM1 4.378 6.913 7.405 2.970 3.508 2.970 −14.896 0.0137106 pitrilysin metallopeptidase 1 CPE 8.958 9.792 8.563 5.451 4.678 5.786 −14.777 0.0010770 carboxypeptidase E CCNG1 6.275 7.621 7.582 3.218 3.739 2.648 −14.740 0.0010499 cyclin G1 PLEKHA9 0.648 4.529 4.632 0.648 0.648 0.648 −14.735 0.0382638 No description PSMA2 7.473 9.614 9.563 5.734 5.557 5.176 −14.724 0.0054998 proteasome (prosome, macropain) subunit, alpha type, 2 RPL38 4.734 9.696 8.685 4.154 4.811 5.459 −14.660 0.0390305 ribosomal protein L38 LDHA 9.890 12.239 11.456 7.584 8.005 7.146 −14.644 0.0041425 lactate dehydrogenase A EIF4A1 6.955 11.946 11.064 6.927 7.202 7.197 −14.589 0.0388794 eukaryotic translation initiation factor 4A1 RRP7A 4.734 6.882 5.570 3.023 1.648 1.648 −14.506 0.0046402 ribosomal RNA processing 7 homolog A (S. cerevisiae) CSRP2 4.008 6.618 5.502 1.648 1.648 1.648 −14.460 0.0038229 cysteine and glycine-rich protein 2 BET1 3.422 5.502 6.151 1.648 1.648 1.648 −14.458 0.0073834 blocked early in transport 1 homolog (S. cerevisiae) ZMYND19 2.233 6.080 6.284 2.233 2.233 2.233 −14.387 0.0379962 zinc finger, MYND-type containing 19 DDOST 5.619 8.444 7.877 4.600 3.294 2.648 −14.361 0.0072967 dolichyl-diphosphooligosaccharide--protein glycosyltransferase MAP2K4 4.817 6.886 7.127 2.951 3.043 3.054 −14.347 0.0068253 mitogen-activated protein kinase kinase 4 EBPL 2.233 6.072 6.120 2.233 2.233 2.233 −14.310 0.0392392 emopamil binding protein-like PTGS2 9.624 10.879 11.105 5.802 5.804 7.275 −14.230 0.0011927 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) TSPAN13 4.264 6.763 7.124 2.648 3.294 2.648 −14.218 0.0114236 tetraspanin 13 TAC1 4.482 7.903 8.109 3.233 3.233 4.299 −14.023 0.0178395 tachykinin, precursor 1 RAB10 6.016 9.289 9.277 5.306 5.480 5.308 −14.015 0.0226894 RAB10, member RAS oncogene family LIMS1 1.648 6.093 5.456 1.648 1.648 1.648 −13.999 0.0366790 LIM and senescent cell antigen-like domains 1 ST8SIA2 6.070 6.849 4.889 2.233 3.043 2.233 −13.983 0.0038998 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 AKR1B1 4.948 9.096 9.005 5.291 3.648 4.013 −13.976 0.0220385 aldo-keto reductase family 1, member B1 (aldose reductase) MSX1 10.601 10.691 9.834 6.036 6.772 7.784 −13.910 0.0028787 msh homeobox 1 IARS2 2.233 6.027 6.032 2.233 2.233 2.233 −13.872 0.0402180 isoleucyl-tRNA synthetase 2, mitochondrial TFF1 5.870 5.996 6.744 2.202 5.462 0.648 −13.871 0.0202742 trefoil factor 1 GBE1 5.688 7.352 7.507 3.718 3.294 2.648 −13.823 0.0032711 glucan (1,4-alpha-), branching enzyme 1 EFNA4 0.648 4.435 5.053 0.648 0.648 0.648 −13.805 0.0369882 ephrin-A4 AGK 0.648 4.435 4.713 0.648 0.648 0.648 −13.805 0.0385348 acylglycerol kinase KCNMB4 6.735 3.192 4.428 2.202 0.648 0.648 −13.734 0.0111567 potassium large conductance calcium-activated channel, subfamily M, beta member 4 C18orf32 4.008 6.943 6.532 3.023 1.648 2.752 −13.731 0.0111837 chromosome 18 open reading frame 32 KHSRP 8.790 10.874 10.278 6.443 6.745 6.503 −13.692 0.0039539 KH-type splicing regulatory protein TIMP2 12.402 12.959 11.428 8.074 7.958 9.195 −13.590 0.0017161 TIMP metallopeptidase inhibitor 2 RAB23 1.648 5.502 5.412 1.648 1.648 1.648 −13.587 0.0400308 RAB23, member RAS oncogene family OLFML1 8.845 6.725 3.702 2.970 2.970 2.970 −13.497 0.0212510 olfactomedin-like 1 FUS 8.319 10.917 10.446 7.165 6.238 6.364 −13.473 0.0085064 fused in sarcoma BMP3 5.861 7.687 7.405 3.218 3.659 3.694 −13.417 0.0032953 bone morphogenetic protein 3 MBD2 5.264 8.614 8.720 4.624 4.529 4.975 −13.404 0.0243823 methyl-CpG binding domain protein 2 LASP1 8.565 9.202 8.478 4.824 4.108 5.814 −13.369 0.0014090 LIM and SH3 protein 1 C1orf55 7.612 10.360 8.788 5.164 5.022 5.049 −13.352 0.0036988 chromosome 1 open reading frame 55 C7orf68 3.233 6.967 7.798 3.233 3.233 3.233 −13.306 0.0367546 chromosome 7 open reading frame 68 CYP7B1 0.648 5.119 4.381 0.648 0.648 0.648 −13.295 0.0371497 cytochrome P450, family 7, subfamily B, polypeptide 1 SCARB2 8.340 9.123 8.591 5.384 4.667 4.875 −13.139 0.0005605 scavenger receptor class B, member 2 MARCH7 3.233 7.351 7.317 3.637 3.233 3.233 −13.130 0.0429702 membrane-associated ring finger (C3HC4) 7 MXRA8 11.216 10.021 10.434 5.899 6.732 8.137 −13.010 0.0041154 matrix-remodelling associated 8 SLC7A3 6.522 4.335 2.714 0.648 0.648 0.648 −12.876 0.0076530 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 LAPTM4B 7.259 9.287 9.101 5.604 5.343 5.279 −12.842 0.0064031 lysosomal protein transmembrane 4 beta CCNI 8.217 11.531 9.815 6.692 5.140 6.137 −12.807 0.0070922 cyclin I ECHDC3 1.648 6.265 5.314 1.648 1.648 1.648 −12.694 0.0372302 enoyl CoA hydratase domain containing 3 C3orf14 4.314 3.644 4.908 0.648 0.648 0.648 −12.687 0.0007955 chromosome 3 open reading frame 14 C7orf55 4.314 5.514 5.222 2.202 0.648 0.648 −12.687 0.0020163 chromosome 7 open reading frame 55 MRPS11 4.314 4.372 4.901 0.648 2.353 0.648 −12.687 0.0042056 mitochondrial ribosomal protein S11 C17orf95 4.314 5.761 5.742 3.081 0.648 0.648 −12.687 0.0056558 chromosome 17 open reading frame 95 CSTA 0.648 4.632 4.314 0.648 0.648 0.648 −12.687 0.0399830 cystatin A (stefin A) P4HA2 5.109 5.898 6.235 2.233 2.233 2.233 −12.684 0.0008634 prolyl 4-hydroxylase, alpha polypeptide II SRPRB 5.423 8.814 8.027 4.886 4.368 4.294 −12.629 0.0190021 signal recognition particle receptor, B subunit PAPSS1 7.297 6.785 6.412 3.494 3.659 2.648 −12.456 0.0011040 3′-phosphoadenosine 5′-phosphosulfate synthase 1 CAMLG 6.047 7.646 8.254 3.648 4.007 4.013 −12.453 0.0044510 calcium modulating ligand SNX25 3.422 5.404 5.281 1.648 1.648 1.648 −12.403 0.0070652 sorting nexin 25 TMED7 6.463 10.098 8.564 6.235 4.591 4.932 −12.393 0.0183719 transmembrane emp24 protein transport domain containing 7 MRPS33 4.734 5.789 5.272 1.648 1.648 1.648 −12.329 0.0006284 mitochondrial ribosomal protein S33 SLC25A32 4.657 8.217 7.180 3.871 3.559 2.233 −12.309 0.0132627 solute carrier family 25, member 32 WISP2 4.793 8.437 8.036 3.233 4.135 4.817 −12.298 0.0229619 WNT1 inducible signaling pathway protein 2 COX8A 9.285 10.229 10.127 6.609 6.264 6.323 −12.288 0.0008315 cytochrome c oxidase subunit VIlIA (ubiquitous) ISCU 6.845 7.814 8.173 4.165 4.247 4.199 −12.249 0.0015269 iron-sulfur cluster scaffold homolog (E. coli)) VEZT 6.610 7.777 7.582 3.951 3.978 4.007 −12.158 0.0014541 vezatin, adherens junctions transmembrane protein S100A8 2.648 6.239 7.006 2.648 2.648 2.648 −12.049 0.0388288 S100 calcium binding protein A8 GEM 8.856 10.606 10.092 5.267 6.230 7.827 −12.036 0.0085272 GTP binding protein overexpressed in skeletal muscle RPSAP58 11.590 13.231 12.770 8.898 9.182 9.570 −12.019 0.0033258 ribosomal protein SA pseudogene 58 LY96 6.001 4.235 3.718 0.648 0.648 0.648 −12.017 0.0019802 lymphocyte antigen 96 SLC7A6OS 0.648 4.795 4.235 0.648 0.648 0.648 −12.017 0.0397362 solute carrier family 7, member 6 opposite strand RRAS2 5.904 8.600 7.859 4.273 4.378 4.049 −12.013 0.0085986 related RAS viral (r-ras) oncogene homolog 2 PTGES3 8.652 11.824 11.781 7.942 7.497 8.251 −11.902 0.0212281 prostaglandin E synthase 3 (cytosolic) SOD1 6.887 9.505 9.175 5.782 5.250 5.606 −11.874 0.0123338 superoxide dismutase 1, soluble GNAS 8.818 11.815 11.623 8.059 8.198 7.983 −11.826 0.0223497 GNAS complex locus WBP5 5.550 7.951 8.387 4.262 4.602 4.389 −11.810 0.0152364 WW domain binding protein 5 AMIGO2 6.418 7.391 7.989 3.830 5.783 1.648 −11.803 0.0150319 adhesion molecule with Ig-like domain 2 EEF1A1 8.720 10.129 10.204 6.464 5.658 6.647 −11.772 0.0032440 eukaryotic translation elongation factor 1 alpha 1 HNRNPUL1 7.595 9.714 9.222 5.668 5.052 5.718 −11.747 0.0049563 heterogeneous nuclear ribonucleoprotein U-like 1 GBAS 2.648 6.196 6.205 2.648 2.648 2.648 −11.693 0.0438208 glioblastoma amplified sequence SGK1 7.602 10.239 9.861 5.784 6.350 6.315 −11.682 0.0109854 serum/glucocorticoid regulated kinase 1 SLBP 4.620 7.890 7.643 3.494 3.852 4.346 −11.665 0.0224870 stem-loop binding protein GNAI3 6.704 8.598 8.589 5.056 4.865 4.623 −11.643 0.0063941 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 THBS4 10.886 8.717 7.042 5.137 5.250 5.176 −11.642 0.0095040 thrombospondin 4 YEATS4 1.648 5.413 5.190 1.648 1.648 1.648 −11.642 0.0423886 YEATS domain containing 4 RPLP2 13.366 14.996 14.847 11.198 11.371 11.320 −11.526 0.0044967 ribosomal protein, large, P2 RNF130 5.683 6.808 6.073 3.023 1.648 3.294 −11.425 0.0031671 ring finger protein 130 GULP1 3.456 6.963 7.763 3.456 3.456 3.456 −11.369 0.0397785 GULP, engulfment adaptor PTB domain containing 1 ZBED3 6.911 4.154 5.246 3.351 2.353 0.648 −11.356 0.0142236 zinc finger, BED-type containing 3 MRPL13 0.648 5.411 4.154 0.648 0.648 0.648 −11.356 0.0381889 mitochondrial ribosomal protein L13 PI16 8.889 9.894 7.940 3.808 5.384 6.499 −11.350 0.0071061 peptidase inhibitor 16 OTUD1 6.466 8.662 7.356 3.988 2.970 4.533 −11.283 0.0045286 OTU domain containing 1 LGALS3BP 7.493 8.314 6.636 3.997 4.383 3.865 −11.279 0.0026638 lectin, galactoside-binding, soluble, 3 binding protein POSTN 7.307 8.035 7.141 3.818 3.818 3.818 −11.229 0.0004884 periostin, osteoblast specific factor MMGT1 6.388 8.099 7.436 4.625 3.648 3.648 −11.111 0.0040399 membrane magnesium transporter 1 LRP12 4.895 7.131 6.122 2.648 2.648 3.303 −11.107 0.0065348 low density lipoprotein receptor-related protein 12 CHMP2B 5.923 8.099 8.028 3.648 3.648 4.631 −11.069 0.0066880 chromatin modifying protein 2B PHLDA3 4.895 6.748 6.116 2.648 2.648 2.648 −11.060 0.0037439 pleckstrin homology-like domain, family A, member 3 C2orf40 9.640 8.820 6.264 3.981 6.181 3.737 −11.000 0.0137688 chromosome 2 open reading frame 40 CAPN6 8.455 6.163 6.427 2.970 2.970 3.859 −10.982 0.0040038 calpain 6 LOXL3 6.232 5.228 5.102 3.023 1.648 1.648 −10.960 0.0034049 lysyl oxidase-like 3 FEN1 4.620 6.101 6.151 2.648 2.648 2.648 −10.947 0.0051650 flap structure-specific endonuclease 1 NAMPT 8.550 10.702 10.016 7.255 6.481 6.222 −10.906 0.0078471 nicotinamide phosphoribosyltransferase TMEM45A 2.233 6.054 5.679 2.233 2.233 2.233 −10.895 0.0428912 transmembrane protein 45A GYPC 9.157 9.098 8.221 6.736 5.282 4.778 −10.873 0.0057577 glycophorin C (Gerbich blood group) SUB1 6.898 8.231 8.010 5.417 4.504 3.456 −10.870 0.0062402 SUB1 homolog (S. cerevisiae) MTATP6 11.596 13.166 13.325 9.651 9.814 9.727 −10.851 0.0061903 No description PHKG2 1.648 5.568 5.082 1.648 1.648 1.648 −10.806 0.0424205 phosphorylase kinase, gamma 2 (testis) PGCP 6.227 7.185 4.878 2.648 2.648 3.752 −10.795 0.0092773 No description MRC2 10.923 10.598 10.016 6.301 7.171 8.415 −10.757 0.0059934 mannose receptor, C type 2 GNG5 5.826 8.593 8.834 5.408 4.781 4.458 −10.749 0.0186340 guanine nucleotide binding protein (G protein), gamma 5 STOML2 8.248 9.444 9.433 6.532 5.405 4.830 −10.687 0.0038818 stomatin (EPB72)-like 2 EIF6 7.692 9.635 9.601 6.224 6.154 5.009 −10.636 0.0079456 eukaryotic translation initiation factor 6 RPS27 13.292 14.938 14.687 10.606 10.822 11.528 −10.634 0.0039629 ribosomal protein S27 CXCL14 8.889 10.897 7.529 4.124 6.103 5.980 −10.597 0.0105397 chemokine (C-X-C motif) ligand 14 DYNLRB1 7.533 8.553 8.121 5.735 4.717 3.516 −10.589 0.0050700 dynein, light chain, roadblock-type 1 LOC154761 6.444 4.845 5.718 2.233 3.043 2.233 −10.565 0.0042880 No description KEAP1 4.214 7.786 8.349 4.385 4.447 3.865 −10.559 0.0416426 kelch-like ECH-associated protein 1 PON2 4.142 6.454 5.945 2.233 2.233 3.054 −10.555 0.0100912 paraoxonase 2 CHMP2A 6.368 8.541 8.819 5.256 3.958 5.147 −10.512 0.0112835 chromatin modifying protein 2A HOXD8 5.042 6.042 5.183 1.648 1.648 3.294 −10.511 0.0053050 homeobox D8 CPZ 8.970 7.638 6.306 4.248 4.383 3.456 −10.482 0.0053827 carboxypeptidase Z LOC388796 5.552 9.155 8.702 4.117 5.766 4.579 −10.476 0.0238166 No description DUSP6 7.928 9.233 9.378 5.961 5.846 5.597 −10.461 0.0041875 dual specificity phosphatase 6 SH3BGRL 6.798 7.959 6.603 3.218 3.852 3.897 −10.450 0.0020253 SH3 domain binding glutamic acid-rich protein like LGALS1 11.317 11.360 10.355 7.977 7.435 7.902 −10.435 0.0018541 lectin, galactoside-binding, soluble, 1 HEPH 7.097 5.617 5.317 2.233 2.233 2.233 −10.435 0.0015900 hephaestin GLUD2 0.648 4.757 4.021 0.648 0.648 0.648 −10.361 0.0421064 glutamate dehydrogenase 2 C11orf1 0.648 4.021 4.389 0.648 0.648 0.648 −10.361 0.0440371 chromosome 11 open reading frame 1 CSRNP2 6.667 8.380 7.170 4.165 3.294 4.199 −10.357 0.0030208 cysteine-serine-rich nuclear protein 2 HNRNPAB 8.494 11.314 10.605 6.996 7.350 7.239 −10.310 0.0132378 heterogeneous nuclear ribonucleoprotein A/B IL28RA 4.423 5.008 5.591 1.648 1.648 1.648 −10.264 0.0011747 interleukin 28 receptor, alpha (interferon, lambda receptor) S100A4 4.264 8.960 6.663 3.494 3.294 3.303 −10.262 0.0211380 S100 calcium binding protein A4 LOXL2 8.577 8.370 8.803 6.860 5.012 5.186 −10.251 0.0079276 lysyl oxidase-like 2 ISG15 8.331 6.016 7.042 4.151 3.686 3.508 −10.237 0.0054277 ISG15 ubiquitin-like modifier DNAJB9 6.705 9.387 8.699 5.450 4.383 5.347 −10.211 0.0103012 DnaJ (Hsp40) homolog, subfamily B, member 9 ATXN10 6.145 7.652 7.661 4.315 3.852 3.303 −10.168 0.0038908 ataxin 10 DPM1 2.233 5.659 5.578 2.233 2.233 2.233 −10.158 0.0467227 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit SF3B14 6.829 8.560 8.726 4.624 5.304 5.220 −10.130 0.0077411 No description SCARA5 7.510 8.184 7.448 4.659 4.108 4.580 −10.124 0.0010950 scavenger receptor class A, member 5 (putative) KCNH6 7.008 9.021 9.843 5.853 4.432 5.686 −10.090 0.0107685 potassium voltage-gated channel, subfamily H (eag-related), member 6 CCDC53 5.598 6.012 4.979 3.023 1.648 1.648 −10.062 0.0030388 coiled-coil domain containing 53 PVRL2 9.881 8.883 9.698 6.363 6.552 5.934 −10.048 0.0018631 poliovirus receptor-related 2 (herpesvirus entry mediator B) CDK2AP1 9.528 10.140 10.195 7.417 6.812 5.726 −10.039 0.0035123 cyclin-dependent kinase 2 associated protein 1 DBI 6.418 8.282 8.295 4.721 4.529 4.975 −9.987 0.0082721 diazepam binding inhibitor (GABA receptor modulator, acyl- CoA binding protein) CFDP1 4.936 6.361 7.082 3.670 3.043 2.233 −9.971 0.0083061 craniofacial development protein 1 COTL1 6.406 10.131 9.864 5.555 6.818 6.045 −9.941 0.0339844 coactosin-like 1 (Dictyostelium) MFN2 5.345 7.585 7.319 4.132 4.007 3.648 −9.930 0.0116801 mitofusin 2 LOC100216001 0.648 4.587 3.959 0.648 0.648 0.648 −9.921 0.0434520 No description PPP1R2P3 0.648 3.959 4.428 0.648 0.648 0.648 −9.921 0.0444794 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3 HES1 7.851 8.462 8.874 6.474 4.515 5.155 −9.891 0.0075809 hairy and enhancer of split 1, (Drosophila) TMEM173 5.539 6.009 3.381 2.233 2.233 2.233 −9.890 0.0153958 transmembrane protein 173 FGFR1OP2 6.135 6.798 7.153 2.970 2.970 3.859 −9.805 0.0016350 FGFR1 oncogene partner 2 LOC550643 4.008 6.617 6.031 3.326 1.648 1.648 −9.790 0.0105674 No description NDUFAB1 4.423 7.381 6.535 3.707 3.247 1.648 −9.768 0.0141938 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1,8 kDa YIF1A 8.300 7.727 8.150 5.966 4.863 3.516 −9.760 0.0064988 Yip1 interacting factor homolog A (S. cerevisiae) RPF2 4.312 8.055 7.893 4.610 4.722 3.905 −9.734 0.0494534 ribosome production factor 2 homolog (S. cerevisiae) RAB1A 6.898 10.273 9.662 6.380 6.353 6.418 −9.733 0.0277536 RAB1A, member RAS oncogene family UAP1 5.997 10.459 9.086 5.773 5.804 6.616 −9.731 0.0493958 UDP-N-acteylglucosamine pyrophosphorylase 1 PTPLAD2 4.423 5.615 4.930 1.648 1.648 1.648 −9.724 0.0013009 protein tyrosine phosphatase-like A domain containing 2 SH3BGR 3.422 5.042 4.930 1.648 1.648 1.648 −9.724 0.0071463 SH3 domain binding glutamic acid-rich protein TACR1 3.422 4.930 5.264 1.648 1.648 1.648 −9.724 0.0073057 tachykinin receptor 1 CCDC90B 5.042 5.420 4.930 4.400 1.648 1.648 −9.724 0.0237189 coiled-coil domain containing 90B MRPL21 3.860 5.996 5.444 2.714 0.648 0.648 −9.724 0.0060024 mitochondrial ribosomal protein L21 CCL28 1.648 4.927 5.808 1.648 1.648 1.648 −9.705 0.0427955 chemokine (C-C motif) ligand 28 TMEM69 5.452 4.927 5.038 3.830 1.648 1.648 −9.702 0.0132198 transmembrane protein 69 PPP1R14A 6.983 4.925 3.294 1.648 1.648 1.648 −9.692 0.0115692 protein phosphatase 1, regulatory (inhibitor) subunit 14A TP53 6.820 7.740 7.575 4.302 4.474 2.970 −9.670 0.0028336 tumor protein p53 PPT2 5.503 6.182 4.859 2.233 2.233 2.233 −9.646 0.0018139 palmitoyl-protein thioesterase 2 PPP1CC 8.533 9.689 8.895 5.269 6.240 5.698 −9.605 0.0022728 protein phosphatase 1, catalytic subunit, gamma isozyme SSBP1 3.422 6.012 5.413 1.648 1.648 2.752 −9.579 0.0137418 single-stranded DNA binding protein 1 IMPDH2 7.925 9.132 9.300 5.686 5.923 5.877 −9.546 0.0042971 IMP (inosine 5′-monophosphate) dehydrogenase 2 HNRNPA0 10.474 11.491 10.726 7.575 7.221 7.530 −9.529 0.0009050 heterogeneous nuclear ribonucleoprotein A0 PLRG1 4.744 7.104 6.621 3.218 3.852 3.303 −9.528 0.0143865 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) CAMK2N1 7.241 8.807 7.946 5.445 3.739 5.557 −9.516 0.0087310 calcium/calmodulin-dependent protein kinase II inhibitor 1 C19orf56 8.040 9.559 9.060 6.295 5.561 5.811 −9.506 0.0049113 chromosome 19 open reading frame 56 ACAT1 5.896 6.979 6.285 3.494 3.294 2.648 −9.501 0.0021626 acetyl-CoA acetyltransferase 1 WDR33 7.072 8.377 8.668 5.045 5.129 5.234 −9.496 0.0056468 WD repeat domain 33 PGD 7.136 9.768 10.402 7.156 6.258 6.508 −9.492 0.0310825 phosphogluconate dehydrogenase PLSCR4 7.096 7.808 7.851 4.392 4.355 4.608 −9.468 0.0012017 phospholipid scramblase4 BAX 4.008 6.499 6.742 1.648 3.499 2.752 −9.466 0.0149279 BCL2-associated X protein SLC26A3 0.648 3.888 4.575 0.648 0.648 0.648 −9.446 0.0443664 solute carrier family 26, member 3 DUSP16 4.620 5.886 5.896 2.648 2.648 2.648 −9.434 0.0050971 dual specificity phosphatase 16 VPS37A 4.214 7.614 6.691 3.456 3.456 3.456 −9.420 0.0228308 vacuolar protein sorting 37 homolog A (S. cerevisiae) CD164 7.794 8.663 8.789 5.555 5.063 5.242 −9.408 0.0020433 CD164 molecule, sialomucin ARF6 10.007 11.794 11.439 7.435 8.206 8.436 −9.403 0.0067303 ADP-ribosylation factor 6 ASB13 0.648 4.043 3.881 0.648 0.648 0.648 −9.403 0.0481314 ankyrin repeat and SOCS box-containing 13 FAM96A 4.008 4.874 5.314 1.648 1.648 1.648 −9.358 0.0027449 family with sequence similarity 96, member A CES8 1.648 4.874 5.466 1.648 1.648 1.648 −9.358 0.0451269 No description C14orf129 4.314 4.347 3.873 0.648 0.648 2.370 −9.351 0.0071373 chromosome 14 open reading frame 129 DPCD 4.314 4.587 3.873 0.648 0.648 3.043 −9.351 0.0146125 deleted in primary ciliary dyskinesia homolog (mouse) ANKRD30A 0.648 3.871 4.235 0.648 0.648 0.648 −9.332 0.0466492 ankyrin repeat domain 30A FGB 0.648 3.871 4.021 0.648 0.648 0.648 −9.332 0.0484340 fibrinogen beta chain KLK1 7.421 7.530 8.103 3.351 4.311 7.329 −9.313 0.0311220 kallikrein 1 KDM5B 5.235 6.187 6.278 2.970 2.970 2.970 −9.299 0.0030118 lysine (K)-specific demethylase 5B PSMC4 6.753 9.903 9.783 6.568 6.636 5.678 −9.285 0.0308073 proteasome (prosome, macropain) 26S subunit, ATPase, 4 C2or76 3.860 3.980 3.511 0.648 0.648 0.648 −9.262 0.0006374 chromosome 2 open reading frame 76 ZNF773 3.860 4.564 4.575 2.202 0.648 0.648 −9.262 0.0047463 zinc finger protein 773 LOC139201 3.860 4.665 5.158 0.648 2.353 0.648 −9.262 0.0052239 No description NDUFAF1 3.860 5.119 4.314 0.648 2.353 0.648 −9.262 0.0061543 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 CCL26 3.860 4.389 4.428 0.648 0.648 2.370 −9.262 0.0068163 chemokine (C-C motif) ligand 26 C12orf53 0.648 3.860 4.262 0.648 0.648 0.648 −9.262 0.0465432 chromosome 12 open reading frame 53 CES1 0.648 3.860 4.021 0.648 0.648 0.648 −9.262 0.0485369 carboxylesterase 1 EIF1 9.524 12.338 11.939 8.050 8.316 9.134 −9.219 0.0186991 eukaryotic translation initiation factor 1 REEP5 7.695 10.028 9.629 5.934 6.426 6.480 −9.207 0.0120031 receptor accessory protein 5 ITPRIPL2 8.774 10.452 9.681 6.984 6.479 6.465 −9.199 0.0052419 inositol 1,4,5-triphosphate receptor interacting protein-like 2 GJA1 12.216 12.339 12.665 8.218 9.139 9.774 −9.192 0.0023900 gap junction protein, alpha 1,43 kDa AP2A1 7.325 8.475 8.082 5.275 4.482 4.233 −9.186 0.0026049 adaptor-related protein complex 2, alpha 1 subunit AZIN1 7.519 9.445 9.185 6.107 5.988 5.756 −9.171 0.0098575 antizyme inhibitor 1 IL6 15.466 15.087 13.483 11.967 11.460 11.893 −9.149 0.0083151 interleukin 6 (interferon, beta 2) APH1A 8.257 9.469 9.787 6.422 6.277 5.698 −9.137 0.0049023 anterior pharynx defective 1 homolog A (C. elegans) SERPINA3 6.545 10.678 11.209 5.002 8.025 5.348 −9.094 0.0314208 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), members DYRK3 5.109 7.277 5.412 2.233 2.233 2.233 −9.054 0.0031491 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 PRMT5 5.587 8.698 8.906 5.729 4.869 4.467 −9.048 0.0270776 protein arginine methyltransferase 5 MXRA5 9.005 7.512 7.405 4.684 4.233 5.431 −9.012 0.0054548 matrix-remodelling associated 5 CLEC11A 6.418 6.194 4.751 1.648 3.247 1.648 −9.009 0.0043560 C-type lectin domain family 11, member A TMEM9 5.696 6.140 6.252 2.970 2.970 2.970 −9.000 0.0008544 transmembrane protein 9 C14orf2 4.422 7.667 7.774 4.604 4.378 3.303 −8.997 0.0353924 chromosome 14 open reading frame 2 DULLARD 7.392 8.384 7.927 5.216 4.271 4.553 −8.987 0.0021896 No description ITPKB 7.190 7.979 7.548 4.593 4.108 4.382 −8.981 0.0010679 inositol 1,4,5-trisphosphate 3-kinase B GPNMB 10.423 10.299 9.251 6.007 7.133 7.429 −8.976 0.0050430 glycoprotein (transmembrane) nmb TGIF2 10.252 9.310 8.443 5.945 5.742 7.087 −8.969 0.0074104 TGFB-induced factor homeobox 2 GNB2L1 11.295 12.631 12.580 9.332 9.324 9.467 −8.964 0.0056288 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 NR2F2 10.927 9.894 9.214 8.576 5.277 6.730 −8.962 0.0155040 nuclear receptor subfamily 2, group F, member 2 PRPS2 4.264 6.822 5.898 2.648 3.659 2.648 −8.958 0.0167997 phosphoribosyl pyrophosphate synthetase 2 C7orf70 4.314 3.810 4.901 2.714 0.648 0.648 −8.950 0.0102471 chromosome 7 open reading frame 70 PAQR4 3.860 3.810 4.593 3.351 0.648 0.648 −8.950 0.0244308 progestin and adipoQ receptor family member IV MRPL50 0.648 4.934 3.810 0.648 0.648 0.648 −8.950 0.0436163 mitochondrial ribosomal protein L50 S100P 0.648 3.810 4.665 0.648 0.648 0.648 −8.950 0.0449023 S100 calcium binding protein P DKK3 5.923 9.121 6.810 3.648 4.294 3.648 −8.949 0.0098936 dickkopf homolog 3 (Xenopus laevis) MGMT 4.314 5.514 5.870 3.351 2.353 0.648 −8.947 0.0122929 O-6-methylguanine-DNA methyltransferase COX5B 5.821 7.894 6.209 4.052 3.043 3.054 −8.910 0.0064738 cytochrome c oxidase subunit Vb DARC 9.735 6.293 6.125 2.970 3.508 4.933 −8.906 0.0148558 Duffy blood group, chemokine receptor OLFML3 7.408 7.559 5.825 2.970 2.970 4.405 −8.898 0.0049744 olfactomedin-like 3 LOC649330 8.143 8.607 8.261 5.133 4.990 5.343 −8.890 0.0006915 No description HSPA1B 9.079 11.668 11.684 5.929 7.260 9.522 −8.875 0.0218464 heat shock 70 kDa protein 1B FAM83A 1.648 4.797 5.311 1.648 1.648 1.648 −8.868 0.0469501 family with sequence similarity 83, member A TMEM185A 7.165 7.105 6.806 4.879 3.958 3.574 −8.855 0.0042236 transmembrane protein 185A RPL11 12.263 13.261 13.545 9.940 10.056 10.399 −8.853 0.0043421 ribosomal protein L11 TMEM176B 9.106 8.986 7.960 5.462 5.776 5.963 −8.835 0.0036537 transmembrane protein 176B STC1 12.598 9.876 9.593 7.502 6.895 6.450 −8.834 0.0072787 stanniocalcin 1 COL6A1 10.999 11.594 10.443 8.181 7.604 7.857 −8.826 0.0023088 collagen, type VI, alpha 1 RNF166 5.524 5.288 4.786 1.648 1.648 3.746 −8.799 0.0114915 ring finger protein 166 DCX 9.077 6.428 7.107 3.970 3.970 4.972 −8.795 0.0095823 doublecortin TMEM189 5.982 8.700 7.540 5.656 4.405 2.648 −8.787 0.0176995 transmembrane protein 189 ZNF217 6.135 8.657 8.787 5.522 4.707 5.606 −8.787 0.0224433 zinc finger protein 217 EIF3K 8.752 9.811 9.759 6.624 6.561 6.657 −8.784 0.0037619 eukaryotic translation initiation factor 3, subunit K C6orf62 8.151 9.814 9.374 6.681 5.768 6.213 −8.775 0.0071886 chromosome 6 open reading frame 62 PABPC1 9.000 11.528 11.200 7.839 8.067 8.203 −8.773 0.0192371 poly(A) binding protein, cytoplasmic 1 C1orf77 4.264 6.728 6.825 3.494 2.648 3.694 −8.757 0.0197750 chromosome 1 open reading frame 77 UQCRQ 5.008 8.261 7.906 5.132 4.428 3.897 −8.747 0.0296433 ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5 kDa TGFBI 9.491 9.818 8.698 6.200 5.569 6.753 −8.746 0.0035393 transforming growth factor, beta-induced, 68 kDa PFDN5 7.618 10.611 9.976 6.704 6.850 7.184 −8.735 0.0252142 prefoldin subunit 5 AP1AR 6.280 7.535 7.684 3.797 3.899 4.557 −8.734 0.0044101 adaptor-related protein complex 1 associated regulatory protein ARL4D 6.773 7.019 6.223 3.718 2.648 3.897 −8.701 0.0027539 ADP-ribosylation factor-like 4D NIPSNAP1 6.667 5.487 5.345 3.535 3.467 2.233 −8.644 0.0095414 nipsnap homolog 1 (C. elegans) SRP9 5.499 8.783 8.277 5.673 4.926 4.932 −8.636 0.0370333 signal recognition particle 9 kDa PMPCA 6.070 7.840 7.887 4.664 4.777 3.508 −8.634 0.0101723 peptidase (mitochondrial processing) alpha EGLN1 6.788 9.421 9.778 6.317 5.233 6.640 −8.596 0.0263830 egl nine homolog 1 (C. elegans) PPP3R1 5.532 8.025 7.793 3.997 4.610 4.927 −8.567 0.0190769 protein phosphatase 3, regulatory subunit B, alpha TRIM52 8.187 9.947 10.141 6.853 6.850 6.760 −8.559 0.0124281 tripartite motif-containing 52 BACE2 5.282 6.567 6.924 2.970 3.827 2.970 −8.553 0.0062492 beta-site APP-cleaving enzyme 2 POMC 0.648 3.745 4.389 0.648 0.648 0.648 −8.552 0.0471227 proopiomelanocortin UBE2Q2 2.970 6.943 6.065 2.970 2.970 2.970 −8.544 0.0456745 ubiquitin-conjugating enzyme E2Q family member 2 HEBP1 4.895 6.066 5.742 2.648 2.648 2.648 −8.534 0.0032530 heme binding protein 1 C7orf50 5.821 5.323 5.645 3.278 2.233 2.233 −8.516 0.0030978 chromosome 7 open reading frame 50 RBPJ 5.545 7.584 6.059 3.442 2.970 2.970 −8.508 0.0050069 recombination signal binding protein for immunoglobulin kappa J region PHLPP1 6.767 7.912 7.771 4.682 4.785 4.141 −8.507 0.0039269 PH domain and leucine rich repeat protein phosphatase 1 CTSK 5.322 6.799 5.499 2.951 3.043 2.233 −8.506 0.0044690 cathepsin K RFCS 3.422 4.863 4.737 1.648 1.648 1.648 −8.506 0.0072066 replication factor C (activator 1) 3, 38 kDa XPNPEP2 4.734 4.871 4.667 1.648 1.648 1.648 −8.491 0.0003983 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane- bound THBS1 10.432 11.878 12.075 6.879 9.093 8.797 −8.462 0.0101542 thrombospondin 1 C17orf106 4.817 5.314 5.462 2.233 2.233 2.233 −8.460 0.0012378 chromosome 17 open reading frame 106 TRAPPC3 6.470 7.177 7.695 4.797 4.097 2.648 −8.457 0.0065439 trafficking protein particle complex 3 MARCKS 12.283 11.804 11.368 9.690 7.835 8.725 −8.450 0.0060614 myristoylated alanine-rich protein kinase C substrate DCAKD 5.908 5.829 4.939 1.648 3.247 2.752 −8.439 0.0059844 dephospho-CoA kinase domain containing RPS6KA1 3.947 6.047 6.108 2.970 2.970 2.970 −8.438 0.0194957 ribosomal protein S6 kinase, 90 kDa, polypeptide 1 ZDHHC1 6.103 5.725 6.131 3.218 2.648 2.648 −8.436 0.0010090 zinc finger, DHHC-type containing 1 TACSTD2 8.039 11.355 11.742 6.398 8.665 5.403 −8.434 0.0199955 tumor-associated calcium signal transducer 2 NCBP2 6.283 8.588 7.745 4.670 4.707 3.911 −8.426 0.0080433 nuclear cap binding protein subunit 2, 20 kDa NPC2 9.497 9.896 9.466 6.181 6.823 6.820 −8.418 0.0016170 Niemann-Pick disease, type C2 ORAI3 6.395 6.365 5.718 3.838 3.294 2.648 −8.397 0.0042326 ORAI calcium release-activated calcium modulator 3 RAB8B 6.936 8.740 8.817 5.747 4.580 5.514 −8.396 0.0106312 RAB8B, member RAS oncogene family TPM1 6.585 8.369 7.849 4.508 6.400 3.516 −8.394 0.0200801 tropomyosin 1 (alpha) LOC93622 7.181 8.088 7.629 4.647 4.015 5.019 −8.392 0.0029577 No description PLP1 6.042 4.963 5.717 2.648 2.648 2.648 −8.389 0.0027809 proteolipid protein 1 SNRPD2 7.914 9.927 9.735 6.860 6.204 5.926 −8.383 0.0106548 small nuclear ribonucleoprotein D2 polypeptide 16.5 kDa RPL31 10.628 12.515 12.683 8.733 9.510 9.451 −8.366 0.0129993 ribosomal protein L31 TIAL1 6.013 8.114 8.032 5.051 4.879 4.895 −8.356 0.0175567 TIA1 cytotoxic granule-associated RNA binding protein-like 1 PPME1 6.898 7.714 8.479 5.287 4.581 4.658 −8.319 0.0062991 protein phosphatase methylesterase 1 ARL5B 7.204 6.693 6.512 3.456 3.456 4.646 −8.317 0.0044600 ADP-ribosylation factor-like 5B CDH1 8.815 9.937 10.596 6.245 8.422 5.762 −8.302 0.0156648 cadherin 1, type 1, E-cadherin (epithelial) EIF2S3 8.609 9.835 9.730 6.786 6.618 6.304 −8.281 0.0049653 eukaryotic translation initiation factor 2, subunit 3 gamma, 52 kDa C13orf15 5.322 8.937 6.103 3.278 3.043 3.054 −8.276 0.0096184 chromosome 13 open reading frame 15 GALT 5.400 5.421 4.043 2.202 2.353 2.370 −8.264 0.0076621 galactose-1 -phosphate uridylyltransferase RNF138P1 6.017 7.401 6.439 3.797 2.970 3.516 −8.263 0.0033529 ring finger protein 138 pseudogene 1 DYNLT1 3.619 6.736 7.458 2.951 4.413 2.233 −8.256 0.0351081 dynein, light chain, Tctex-type 1 LZTFL1 3.422 5.409 4.692 1.648 1.648 1.648 −8.245 0.0079047 leucine zipper transcription factor-like 1 EID1 8.386 8.969 8.510 5.715 4.097 5.928 −8.231 0.0039088 EP300 interacting inhibitor of differentiation 1 C9orf16 6.735 7.330 7.173 4.117 5.189 3.694 −8.226 0.0070021 chromosome 9 open reading frame 16 MFAP2 5.688 5.081 5.729 2.648 2.648 2.648 −8.224 0.0017958 microfibrillar-associated protein 2 VEGFB 8.740 8.080 8.015 6.231 5.040 4.937 −8.223 0.0055608 vascular endothelial growth factor B PMVK 3.422 5.778 5.082 1.648 2.739 1.648 −8.217 0.0146887 phosphomevalonate kinase DSC2 6.047 7.787 8.761 4.442 5.725 4.603 −8.203 0.0209640 desmocollin 2 ABHD14B 8.820 7.419 7.372 5.384 4.339 5.579 −8.183 0.0098305 abhydrolase domain containing 14B BMI1 4.214 7.142 6.487 3.456 3.456 3.865 −8.174 0.0285792 BMI1 polycomb ring finger oncogene GADD45B 13.444 11.739 11.951 8.605 10.110 10.414 −8.170 0.0157043 growth arrest and DNA-damage-inducible, beta SH3KBP1 7.476 7.038 7.538 5.418 4.240 4.013 −8.144 0.0060953 SH3-domain kinase binding protein 1 PHF23 5.977 7.459 7.431 4.273 4.135 4.436 −8.133 0.0081286 PHD finger protein 23 CDIPT 7.511 8.289 8.227 6.038 4.007 5.205 −8.128 0.0083421 CDP-diacylglycerol inositol 3-phosphatidyltransferase SLC39A7 7.347 8.720 8.186 5.818 5.166 4.141 −8.110 0.0069841 solute carrier family 39 (zinc transporter), member 7 COX5A 5.552 7.799 8.201 4.482 5.085 4.781 −8.097 0.0247248 cytochrome c oxidase subunit Va SPTLC1 5.705 6.967 7.165 3.951 3.978 3.701 −8.089 0.0068073 serine palmitoyltransferase, long chain base subunit 1 GTF2H2D 0.648 3.664 4.972 0.648 0.648 0.648 −8.088 0.0454139 general transcription factor IIH, polypeptide 2D TSPAN1 0.648 3.664 4.665 0.648 0.648 0.648 −8.088 0.0466104 tetraspanin 1 MAGED1 1.648 6.253 4.663 1.648 1.648 1.648 −8.083 0.0446873 melanoma antigen family D, 1 USP14 5.204 8.477 8.332 5.412 5.318 4.409 −8.082 0.0436932 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) TIMM8B 4.423 7.733 7.388 4.376 4.529 3.557 −8.067 0.0386735 translocase of inner mitochondrial membrane 8 homolog B (yeast) GPR124 8.639 7.485 6.863 4.233 4.482 4.672 −8.014 0.0040849 G protein-coupled receptor 124 HOXC6 5.204 5.491 4.632 2.202 0.648 3.351 −8.013 0.0110464 homeobox C6 EGFL6 7.531 3.644 2.714 0.648 0.648 2.370 −7.974 0.0246582 EGF-like-domain, multiple 6 NAA50 6.160 9.178 8.920 5.899 5.449 6.184 −7.965 0.0384676 N(alpha)-acetyltransferase 50, NatE catalytic subunit TOMM22 6.980 9.851 8.439 6.522 5.449 5.202 −7.941 0.0197113 translocase of outer mitochondrial membrane 22 homolog (yeast) C22orf28 3.619 6.266 6.886 3.278 3.467 2.233 −7.938 0.0280184 chromosome 22 open reading frame 28 STT3A 7.652 8.133 8.130 6.601 5.143 4.579 −7.929 0.0138360 STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) CNKSR3 5.169 6.771 6.029 2.951 3.043 3.054 −7.924 0.0045556 CNKSR family member 3 TNFRSF10D 4.872 7.197 7.277 3.997 3.859 4.293 −7.909 0.0232939 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain SLC9A7 0.648 3.631 4.934 0.648 0.648 0.648 −7.905 0.0458575 solute carrier family 9 (sodium/hydrogen exchanger), member 7 EBNA1BP2 3.619 6.992 6.517 3.535 2.233 3.737 −7.901 0.0338839 EBNA1 binding protein 2 ATP6AP2 7.002 7.269 6.208 5.315 3.233 3.233 −7.862 0.0115511 ATPase, H+ transporting, lysosomal accessory protein 2 MRPL24 6.470 6.818 7.067 3.897 4.097 2.648 −7.837 0.0032170 mitochondrial ribosomal protein L24 SLC35B2 6.756 7.635 7.946 4.670 3.508 5.270 −7.809 0.0077050 solute carrier family 35, member B2 ANKRD10 8.359 8.831 9.305 6.340 5.140 5.955 −7.807 0.0039809 ankyrin repeat domain 10 DLK1 5.222 5.915 6.259 2.648 3.294 2.648 −7.806 0.0034783 delta-like 1 homolog (Drosophila) CCDC82 4.620 6.299 5.607 2.648 2.648 2.648 −7.776 0.0058763 coiled-coil domain containing 82 CAPZA2 5.690 8.482 7.823 4.463 5.525 4.293 −7.767 0.0234513 capping protein (actin filament) muscle Z-line, alpha 2 PIM2 6.203 7.836 5.926 4.042 2.970 4.673 −7.760 0.0141064 pim-2 oncogene SHMT2 5.107 8.348 7.540 5.395 4.447 4.141 −7.745 0.0370062 serine hydroxymethyltransferase 2 (mitochondrial) FBXO32 4.826 8.354 7.627 4.675 5.034 3.516 −7.740 0.0352246 F-box protein 32 GTF2H5 7.307 8.285 7.668 5.553 4.355 4.712 −7.736 0.0051560 general transcription factor IIH, polypeptide 5 SFRP2 9.353 7.454 6.352 4.655 4.405 4.507 −7.713 0.0104669 secreted frizzled-related protein 2 BRMS1 3.860 6.231 5.343 2.714 3.284 0.648 −7.712 0.0190111 breast cancer metastasis suppressor 1 ELF1 8.259 8.835 8.361 5.421 4.600 6.178 −7.674 0.0041335 E74-like factor 1 (ets domain transcription factor) TRMT112 7.304 9.727 8.958 6.457 6.019 4.581 −7.672 0.0141847 tRNA methyltransferase 11-2 homolog (S. cerevisiae) RNPS1 5.107 8.215 8.199 4.728 5.011 5.277 −7.664 0.0465023 RNA binding protein S1. serine-rich domain FN1 10.527 11.129 9.255 6.819 7.589 7.994 −7.662 0.0098846 fibronectin 1 DUSP10 4.142 5.888 5.737 2.951 2.233 2.233 −7.656 0.0094666 dual specificity phosphatase 10 ZNF593 4.525 7.754 7.575 4.378 4.818 3.737 −7.654 0.0415657 zinc finger protein 593 DLC1 6.734 7.317 7.266 4.108 4.108 4.382 −7.652 0.0015809 deleted in liver cancer 1 RBM15 4.422 6.723 5.584 2.648 2.648 3.303 −7.651 0.0128412 RNA binding motif protein 15 PRPF31 4.817 6.502 5.886 2.951 3.043 2.233 −7.647 0.0059393 PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) CRIM1 4.672 8.063 7.065 4.132 4.294 3.648 −7.635 0.0267095 cysteine rich transmembrane BMP regulator 1 (chordin-like) CD46 6.949 8.600 8.722 5.790 5.528 5.502 −7.631 0.0133778 CD46 molecule, complement regulatory protein SCP2 5.934 5.902 5.990 2.970 3.508 2.970 −7.629 0.0017570 sterol carrier protein 2 VOL 10.585 10.343 9.939 7.407 7.654 7.127 −7.626 0.0019893 vinculin MOBKL2A 7.419 9.003 8.200 6.073 5.838 4.377 −7.623 0.0118028 MOB1, Mps One Binder kinase activator-like 2A (yeast) C19orf10 6.912 9.232 9.829 6.900 5.896 4.579 −7.618 0.0226014 chromosome 19 open reading frame 10 PVRL4 5.899 6.250 7.148 2.970 4.508 2.970 −7.615 0.0079816 poliovirus receptor-related 4 GOLPH3 9.709 9.915 9.776 7.572 6.435 6.847 −7.614 0.0035303 golgi phosphoprotein 3 (coat-protein) SOX17 7.983 5.896 5.263 4.156 2.970 2.970 −7.600 0.0136558 SRY (sex determining region Y)-box 17 NCRNA00116 4.378 6.811 5.896 3.442 2.970 2.970 −7.600 0.0161646 non-protein coding RNA 116 SAR1A 8.769 10.199 9.662 7.046 6.155 6.740 −7.575 0.0056648 SAR1 homolog A (S. cerevisiae) RIOK3 4.539 7.467 7.178 4.225 4.264 4.516 −7.537 0.0456107 RIO kinase 3 (yeast) OLFML2A 8.879 8.519 7.405 5.134 4.989 5.967 −7.526 0.0064392 olfactomedin-like 2A FXYD1 5.644 7.288 5.143 2.951 2.233 3.508 −7.516 0.0082631 FXYD domain containing ion transport regulator 1 RAB40B 6.070 6.418 6.531 2.233 4.500 3.508 −7.513 0.0090617 RAB40B, member RAS oncogene family C7orf60 4.969 6.806 6.815 3.442 3.827 3.911 −7.486 0.0152544 chromosome 7 open reading frame 60 MTCYB 13.951 9.184 9.953 7.050 6.987 7.156 −7.478 0.0134229 No description PRKAR1A 9.779 12.053 12.245 9.344 8.338 8.978 −7.471 0.0230000 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) C19orf40 8.872 9.026 9.068 6.565 5.817 6.125 −7.469 0.0021113 chromosome 19 open reading frame 40 C10orf116 9.685 9.896 8.607 5.929 6.951 6.785 −7.467 0.0065258 chromosome 10 open reading frame 116 CCL2 12.696 11.505 10.195 8.606 8.678 8.043 −7.464 0.0097439 chemokine (C-C motif) ligand 2 FKBP1A 9.411 11.546 11.306 8.647 7.493 7.539 −7.459 0.0124191 FK506 binding protein 1A, 12 kDa ZC3H11A 7.886 9.203 8.855 6.305 5.228 5.688 −7.455 0.0057307 zinc finger CCCH-type containing 11A MRPL54 4.423 6.222 5.997 3.326 2.739 2.752 −7.445 0.0117182 mitochondrial ribosomal protein L54 CBLC 2.233 5.126 6.294 2.233 2.233 2.233 −7.427 0.0482250 Gas-Br-M (murine) ecotropic retroviral transforming sequence c GLT25D1 7.295 8.413 8.254 5.522 5.247 5.125 −7.416 0.0052510 glycosyltransferase 25 domain containing 1 PRSS23 7.743 8.273 6.807 5.384 4.108 4.382 −7.407 0.0064482 protease, serine, 23 PSMB10 3.422 4.536 6.042 2.625 1.648 1.648 −7.402 0.0166735 proteasome (prosome, macropain) subunit, beta type, 10 EPAS1 11.122 11.919 9.707 9.033 8.142 7.743 −7.394 0.0160655 endothelial PAS domain protein 1 YAP1 8.277 10.062 9.479 6.904 6.442 6.594 −7.386 0.0101993 Yes-associated protein 1 TES 9.259 10.515 10.264 7.237 8.489 6.377 −7.374 0.0147026 testis derived transcript (3 LIM domains) DNAJC7 4.709 7.712 7.718 4.240 4.149 4.836 −7.370 0.0374423 DnaJ (Hsp40) homolog, subfamily C, member 7 CHN1 5.109 6.465 5.998 4.052 2.233 2.233 −7.341 0.0091560 chimerin (chimaerin) 1 TAF6 5.109 5.860 5.686 4.575 2.233 2.233 −7.341 0.0197841 TAF6 RNA polymerase II, TATA box binding protein (TBP)- associated factor, 80 kDa ATP5F1 6.791 8.724 7.774 5.472 3.739 5.851 −7.330 0.0166007 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 AR 6.667 5.367 5.104 3.278 3.043 2.233 −7.317 0.0078062 androgen receptor MLF1 4.524 7.059 5.836 2.970 2.970 2.970 −7.290 0.0117452 myeloid leukemia factor 1 SPARCL1 8.267 10.199 7.614 5.401 5.506 5.112 −7.287 0.0068794 SPARC-like 1 (hevin) PKIG 10.339 9.699 9.496 8.036 6.543 6.839 −7.264 0.0083962 protein kinase (cAMP-dependent, catalytic) inhibitor gamma SDCBP 10.061 11.081 11.021 8.225 7.755 8.132 −7.239 0.0051199 syndecan binding protein (syntenin) KIAA1467 3.619 5.321 5.088 2.233 2.233 2.233 −7.232 0.0126263 KIAA1467 LAPTM4A 12.501 13.235 12.288 10.626 9.329 9.648 −7.223 0.0063130 lysosomal protein transmembrane 4 alpha PCOLCE 7.672 9.106 7.785 4.876 4.933 6.257 −7.202 0.0097529 procollagen C-endopeptidase enhancer RNF103 5.039 7.601 7.503 3.637 4.135 4.759 −7.170 0.0233120 ring finger protein 103 LATS2 8.899 10.122 10.771 6.975 7.283 7.500 −7.155 0.0101182 LATS, large tumor suppressor, homolog 2 (Drosophila) HSD17B11 8.818 8.712 7.227 5.979 4.861 5.808 −7.154 0.0109314 hydroxysteroid (17-beta) dehydrogenase 11 ARL1 7.361 7.327 6.873 5.564 4.490 3.233 −7.150 0.0118839 ADP-ribosylation factor-like 1 EFEMP1 5.596 9.170 6.703 3.808 4.447 3.865 −7.147 0.0160399 EGF-containing fibulin-like extracellular matrix protein 1 MFAP5 8.490 8.657 6.638 3.848 4.791 5.821 −7.139 0.0110797 microfibrillar associated protein 5 CXCL12 11.917 10.511 9.404 7.399 7.543 9.082 −7.138 0.0215997 chemokine (C-X-C motif) ligand 12 IGFBP6 9.376 9.287 8.911 6.567 6.035 6.454 −7.128 0.0019262 insulin-like growth factor binding protein 6 SRGN 7.233 10.960 7.100 6.131 4.273 5.682 −7.099 0.0261307 serglycin LRRC61 5.870 4.901 5.128 0.648 2.353 3.043 −7.095 0.0072607 leucine rich repeat containing 61 RCAN1 5.482 7.775 6.461 3.637 3.233 3.701 −7.086 0.0078811 regulator of calcineurin 1 ERRFU 8.265 11.804 11.440 7.483 7.122 8.985 −7.056 0.0351539 ERBB receptor feedback inhibitor 1 SNAPC3 5.861 5.466 6.697 3.494 3.294 2.648 −7.049 0.0050880 small nuclear RNA activating complex, polypeptide 3, 50 kDa TWSG1 4.826 7.856 6.857 3.442 4.289 4.042 −7.038 0.0229099 twisted gastrulation homolog 1 (Drosophila) CCDC83 3.194 5.166 4.771 0.648 2.353 0.648 −7.029 0.0098215 coiled-coil domain containing 83 CTDSP1 10.292 9.879 9.227 7.667 6.417 6.429 −7.010 0.0055698 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 DNAJC14 5.204 6.918 6.264 3.456 3.456 3.865 −7.006 0.0107373 DnaJ (Hsp40) homolog, subfamily C, member 14 INSIG1 8.532 7.890 8.078 5.157 5.083 6.309 −6.994 0.0072336 insulin induced gene 1 EFCAB4A 4.008 4.454 5.869 1.648 1.648 2.752 −6.993 0.0113016 EF-hand calcium binding domain 4A PCDHB14 4.647 4.665 3.452 0.648 0.648 2.370 −6.981 0.0084634 protocadherin beta 14 SHQ1 4.744 5.531 5.448 2.648 2.648 2.648 −6.962 0.0039179 SHQ1 homolog (S. cerevisiae) C15orf44 5.600 7.136 7.184 4.385 4.149 2.970 −6.960 0.0109494 chromosome 15 open reading frame 44 MKRN2 4.872 6.774 6.955 4.159 3.859 3.865 −6.944 0.0228399 makorin ring finger protein 2 REST 6.679 5.546 6.287 3.494 2.648 4.538 −6.931 0.0128232 RE1-silencing transcription factor TBCB 5.377 7.455 6.448 3.897 3.659 2.648 −6.916 0.0087491 tubulin folding cofactor B CHRNE 6.324 5.167 4.928 3.535 2.233 2.233 −6.910 0.0092503 cholinergic receptor, nicotinic, epsilon PTP4A3 8.433 6.618 6.318 3.830 5.197 3.557 −6.905 0.0129175 protein tyrosine phosphatase type IVA, member 3 EPHX2 6.829 4.600 5.648 1.648 3.892 4.043 −6.894 0.0285314 epoxide hydrolase 2, cytoplasmic CCDC111 3.194 3.431 4.262 0.648 0.648 0.648 −6.884 0.0025251 coiled-coil domain containing 111 ZFP36L1 13.356 12.879 11.506 10.422 8.720 10.575 −6.873 0.0166187 zinc finger protein 36, C3H type-like 1 TMEM203 3.619 6.794 6.817 2.951 4.037 3.054 −6.868 0.0381265 transmembrane protein 203 KDELR1 10.091 10.895 10.422 8.116 7.612 7.538 −6.865 0.0037709 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 APPL2 3.792 6.271 6.151 3.494 3.294 2.648 −6.856 0.0297009 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 KCNA6 4.423 4.117 5.010 1.648 1.648 1.648 −6.844 0.0022818 potassium voltage-gated channel, shaker-related subfamily, member 6 PC 4.423 4.975 5.191 3.023 1.648 1.648 −6.844 0.0075449 pyruvate carboxylase FGFBP2 4.423 5.926 3.602 1.648 1.648 2.752 −6.844 0.0162492 fibroblast growth factor binding protein 2 MIER2 4.423 5.811 6.706 1.648 3.499 3.929 −6.844 0.0235179 mesoderm induction early response 1, family member 2 LYZ 4.423 5.772 1.729 1.648 1.648 1.648 −6.844 0.0464059 lysozyme KDELR2 10.055 11.338 10.908 8.566 7.736 7.616 −6.831 0.0064121 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 GNAI2 10.238 9.744 8.865 7.365 6.301 6.974 −6.820 0.0076960 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 TMEM138 5.160 5.807 5.910 4.234 3.043 2.233 −6.793 0.0153868 transmembrane protein 138 OSBPL9 3.792 6.728 6.257 3.494 3.659 2.648 −6.788 0.0329854 oxysterol binding protein-like 9 ETV6 8.062 8.001 8.000 5.245 6.196 5.092 −6.755 0.0066610 ets variant 6 PCDH18 7.826 7.341 8.057 4.764 4.585 5.687 −6.753 0.0055088 protocadherin 18 DSTN 6.641 9.276 8.648 5.892 6.521 5.504 −6.750 0.0315199 destrin (actin depolymerizing factor) GABARAPL2 6.262 7.079 7.011 4.033 4.624 3.508 −6.746 0.0057487 GABA(A) receptor-associated protein-like 2 HERPUD1 7.540 9.647 9.440 6.894 6.500 5.525 −6.740 0.0179816 homocysteine-inducible, endoplasmic reticulum stress- inducible, ubiquitin-like domain member 1 HADH 6.798 6.354 7.363 4.182 4.015 4.049 −6.723 0.0035213 hydroxyacyl-CoA dehydrogenase PPP1R1A 3.422 4.395 4.930 1.648 1.648 1.648 −6.711 0.0078381 protein phosphatase 1, regulatory (inhibitor) subunit 1A RFC2 3.422 4.395 5.228 1.648 1.648 1.648 −6.711 0.0084544 replication factor C (activator 1) 2, 40 kDa STOM 13.706 12.688 11.832 10.413 9.739 9.943 −6.704 0.0097709 stomatin DBC1 5.396 5.405 4.977 2.233 3.686 2.233 −6.698 0.0103747 deleted in bladder cancer 1 SCAND1 7.268 7.867 8.253 5.502 5.512 4.493 −6.683 0.0075088 SCAN domain containing 1 PIN1 7.268 6.685 6.844 4.877 3.892 4.104 −6.679 0.0052690 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 HDAC11 6.291 5.464 5.385 3.718 2.648 2.648 −6.668 0.0069660 histone deacetylase 11 SLC25A17 3.619 6.096 4.970 2.233 2.233 2.233 −6.665 0.0141515 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34 kDa), member 17 SKP1 9.094 11.128 11.054 8.128 8.394 8.061 −6.656 0.0230763 S-phase kinase-associated protein 1 MICAL2 6.320 7.510 6.415 3.682 5.518 3.516 −6.649 0.0180724 microtubule associated monoxygenase, calponin and LIM domain containing 2 NME7 5.908 6.030 5.979 4.017 3.247 2.752 −6.645 0.0057938 non-metastatic cells 7, protein expressed in (nucleoside- diphosphate kinase) FAM82A2 5.377 6.277 5.813 2.648 4.628 2.648 −6.630 0.0166506 family with sequence similarity 82, member A2 SEMA3G 7.157 6.868 7.072 4.463 4.259 4.141 −6.618 0.0014180 sema domain, immunoglobulin domain (ig), short basic domain, secreted, (semaphorin) 3G PTGDS 6.612 8.995 8.457 5.661 4.508 6.271 −6.609 0.0227754 prostaglandin D2 synthase 21 kDa (brain) IRF2BP2 9.150 10.670 10.207 7.130 6.885 7.947 −6.601 0.0093896 interferon regulatory factor 2 binding protein 2 MMP14 9.037 8.199 8.415 6.361 5.479 5.546 −6.592 0.0048454 matrix metallopeptidase 14 (membrane-inserted) CD8B 6.262 4.950 4.165 2.233 2.233 2.233 −6.572 0.0080953 CD8b molecule AKR1C3 8.973 9.398 10.222 7.846 6.686 5.462 −6.556 0.0124711 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) RBM14 7.483 9.097 8.468 6.069 5.634 5.757 −6.549 0.0101452 RNA binding motif protein 14 SALL2 6.036 5.301 5.632 3.326 3.247 1.648 −6.542 0.0074194 sal-like 2 (Drosophila) TXNL4A 5.173 7.872 7.109 4.883 4.405 3.897 −6.517 0.0275407 thioredoxin-like 4A NDUFA12 4.936 6.238 6.209 3.535 3.467 2.233 −6.510 0.0103837 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex. 12 TNNT3 4.972 6.597 5.687 0.648 2.987 4.602 −6.499 0.0234284 troponin T type 3 (skeletal, fast) FMO1 9.006 5.348 5.909 2.648 3.294 4.199 −6.498 0.0155615 flavin containing monooxygenase 1 PLK2 5.404 7.697 7.209 3.961 4.007 4.997 -6.498 0.0207532 polo-like kinase 2 COL14A1 10.160 8.852 8.108 5.621 6.152 6.236 −6.495 0.0070291 collagen, type XIV, alpha 1 NADSYN1 4.142 5.174 4.932 2.233 2.233 2.233 −6.493 0.0057848 NAD synthetase 1 NGFR 11.046 8.470 8.111 5.413 7.196 6.229 −6.490 0.0190201 nerve growth factor receptor MPDUI 4.657 6.087 4.931 2.233 3.043 2.233 −6.488 0.0080114 mannose-P-dolichol utilization defect 1 HMGB1 3.947 7.174 6.491 3.797 3.827 2.970 −6.471 0.0357425 high-mobility group box 1 C16orf42 6.338 7.407 7.351 4.715 4.265 3.737 −6.460 0.0057757 chromosome 16 open reading frame 42 ADM 6.070 8.800 8.616 5.551 5.561 6.109 −6.457 0.0414596 adrenomedullin RHOB 8.967 11.265 10.619 8.575 7.868 7.792 −6.451 0.0258749 ras homolog gene family, member B SPINTI 6.349 8.706 9.052 5.343 6.363 3.694 −6.448 0.0229459 serine peptidase inhibitor, Kunitz type 1 SCOC 5.008 5.336 6.205 2.648 2.648 2.648 −6.443 0.0036718 short coiled-coil protein TJP2 6.013 7.256 7.412 4.728 4.383 4.409 −6.427 0.0113660 tight junction protein 2 (zona occludens 2) RANBP3 5.171 7.619 7.439 4.935 4.699 4.264 −6.426 0.0346208 RAN binding protein 3 CHST15 9.534 9.887 9.703 7.022 6.573 7.823 −6.412 0.0067844 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 CXCL13 6.541 6.673 7.652 2.625 4.945 4.975 −6.396 0.0159726 chemokine (C-X-C motif) ligand 13 CCL8 6.829 7.267 5.416 6.065 2.739 3.294 −6.395 0.0375990 chemokine (C-C motif) ligand 8 RBBP7 6.689 7.649 8.190 4.946 4.972 5.087 −6.393 0.0090458 retinoblastoma binding protein 7 PIGF 4.008 5.903 6.232 3.557 2.739 2.752 −6.390 0.0218894 phosphatidylinositol glycan anchor biosynthesis, class F ALKBH7 8.127 7.625 8.173 5.462 5.458 5.451 −6.359 0.0033043 alkB, alkylation repair homolog 7 (E. coli)) CAB39 5.690 7.768 7.939 4.159 5.272 4.924 −6.350 0.0244059 calcium binding protein 39 YWHAH 9.341 10.194 10.036 7.089 7.531 6.724 −6.334 0.0044780 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide ADAMTS4 12.322 14.494 11.383 9.723 9.167 9.660 −6.332 0.0113750 ADAM metallopeptidase with thrombospondin type 1 motif, 4 AQP1 7.720 9.280 6.251 4.496 5.746 5.057 −6.330 0.0218984 aquaporin 1 (Colton blood group) NFU1 5.908 6.123 5.706 4.687 3.247 2.752 −6.326 0.0163068 NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) SLFN11 6.811 7.258 5.562 4.151 3.508 4.327 −6.322 0.0117723 schlafen family member 11 PARK7 5.967 6.781 6.678 5.378 4.017 2.752 −6.321 0.0225376 Parkinson disease (autosomal recessive, early onset) 7 SFRS4 7.457 10.035 9.599 6.645 6.800 7.376 −6.318 0.0363386 No description FAH 5.941 5.624 6.191 3.442 3.508 2.970 −6.294 0.0035754 fumarylacetoacetate hydrolase (fumarylacetoacetase) YPEL2 8.675 9.348 8.616 6.691 5.393 6.696 −6.284 0.0087830 yippee-like 2 (Drosophila) MTMR11 7.217 5.390 5.525 4.529 2.739 3.370 −6.281 0.0198499 myotubularin related protein 11 RPN2 7.053 9.003 8.696 6.353 5.308 4.553 −6.276 0.0133868 ribophorin II PTPRS 9.742 8.599 9.172 6.943 5.952 6.887 −6.264 0.0085362 protein tyrosine phosphatase, receptor type, S IGFBP2 9.147 8.799 7.894 6.848 6.157 5.074 −6.244 0.0131775 insulin-like growth factor binding protein 2, 36 kDa TMX2 5.941 7.951 7.426 4.784 4.844 4.327 −6.239 0.0153390 thioredoxin-related transmembrane protein 2 SNX7 4.142 6.574 5.592 2.951 3.043 2.233 −6.237 0.0146284 sorting nexin 7 METTL9 4.331 7.761 6.288 3.648 3.648 3.648 −6.231 0.0286125 methyltransferase like 9 RPL35 12.189 12.878 13.182 10.181 10.545 10.070 −6.223 0.0064572 ribosomal protein L35 C5orf62 7.512 10.089 7.789 6.377 4.876 6.432 −6.217 0.0246159 chromosome 5 open reading frame 62 EFNA3 3.194 4.587 3.284 0.648 0.648 0.648 −6.213 0.0038638 ephrin-A3 ACSL3 5.683 8.186 8.151 4.610 5.557 5.110 −6.187 0.0314458 acyl-CoA synthetase long-chain family member 3 SUGT1 4.525 6.900 6.298 3.670 3.686 3.054 −6.181 0.0196662 SGT 1, suppressor of G2 allele of SKP1 (S. cerevisiae) PIK3IP1 6.003 7.014 6.532 4.196 3.686 3.905 −6.175 0.0054187 phosphoinositide-3-kinase interacting protein 1 RGS5 11.990 11.020 9.193 9.369 7.997 8.222 −6.154 0.0363477 regulator of G-protein signaling 5 IMP3 6.755 8.170 7.637 5.551 5.183 3.737 −6.142 0.0127920 IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast) BANF1 10.023 8.870 8.461 7.393 6.849 5.842 −6.142 0.0167428 barrier to autointegration factor 1 ARAF 5.293 6.286 5.846 3.637 3.233 3.233 −6.119 0.0068523 v-raf murine sarcoma 3611 viral oncogene homolog TMEM8B 5.489 5.916 5.231 2.648 2.648 3.303 −6.115 0.0040489 transmembrane protein 8B C3orf21 6.247 5.976 4.451 3.637 3.233 3.233 −6.107 0.0198021 chromosome 3 open reading frame 21 HDGFRP3 4.312 6.092 6.146 3.535 3.467 2.233 −6.107 0.0194291 No description ARID5B 8.374 10.696 10.742 7.198 6.670 8.132 −6.105 0.0210894 AT rich interactive domain 5B (MRF1-like) CORO1C 5.125 7.561 7.252 4.642 4.456 4.865 −6.104 0.0384523 coronin, actin binding protein, 1C SELK 8.371 10.072 10.082 7.474 6.953 7.181 −6.098 0.0172399 No description PLAT 6.877 8.662 7.327 5.147 4.600 4.724 −6.076 0.0080773 plasminogen activator, tissue TRPT1 4.817 5.751 6.138 3.535 3.043 2.233 −6.072 0.0102083 tRNA phosphotransferase 1 CMPK1 8.673 9.889 9.282 7.287 7.000 5.658 −6.069 0.0117272 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic NAB2 7.053 6.359 6.237 3.637 4.043 4.007 −6.065 0.0040759 NGFI-A binding protein 2 (EGR1 binding protein 2) UBA2 6.318 8.304 7.939 5.357 5.339 4.697 −6.062 0.0173847 ubiquitin-like modifier activating enzyme 2 IFT52 5.503 4.833 5.013 3.670 2.233 2.233 −6.061 0.0129813 intraflagellar transport 52 homolog (Chlamydomonas) RPL13 13.742 14.792 14.180 11.461 11.580 11.650 −6.060 0.0043061 ribosomal protein L13 PYGO2 6.851 6.851 7.028 4.678 4.240 4.264 −6.009 0.0029487 pygopus homolog 2 (Drosophila) TMED9 5.173 5.804 5.327 3.218 2.648 2.648 −6.005 0.0042146 transmembrane emp24 protein transport domain containing 9 EGLN3 5.809 5.830 6.626 3.442 2.970 4.042 −5.998 0.0070832 egl nine homolog 3 (C. elegans) HSPC159 4.817 5.770 4.796 2.233 2.233 2.233 −5.994 0.0030659 No description PLEKHF2 4.817 6.215 6.975 4.151 4.037 2.233 −5.994 0.0230340 pleckstrin homology domain containing, family F (with FYVE domain) member 2 RAP2A 7.243 8.050 8.038 5.488 4.141 5.455 −5.991 0.0077612 RAP2A, member of RAS oncogene family SLC39A1 7.002 8.711 8.409 6.372 5.828 4.007 −5.983 0.0199608 solute carrier family 39 (zinc transporter), member 1 RNF19B 7.533 8.410 8.136 4.966 5.700 5.556 −5.979 0.0054367 ring finger protein 19B SCAMP5 5.781 3.475 4.308 3.202 1.648 1.648 −5.975 0.0263588 secretory carrier membrane protein 5 KLHL21 9.887 11.398 10.774 7.104 8.195 9.235 −5.972 0.0184350 kelch-like21 (Drosophila) DNALI1 5.042 4.225 5.281 3.830 1.648 1.648 −5.966 0.0208801 dynein, axonemal, light intermediate chain 1 OS9 6.612 7.923 7.187 4.042 5.250 5.176 −5.939 0.0135816 osteosarcoma amplified 9. endoplasmic reticulum lectin FBLN7 6.818 6.418 6.481 4.575 3.508 3.911 −5.937 0.0056738 fibulin 7 SLIT3 8.311 7.742 6.498 5.476 4.580 5.173 −5.934 0.0147282 slit homolog 3 (Drosophila) FAM192A 4.086 6.285 6.612 3.637 4.043 3.701 −5.934 0.0491054 family with sequence similarity 192, member A HIF1A 10.317 10.443 9.638 8.472 7.234 7.074 −5.916 0.0104759 hypoxia inducible factor 1, alpha subunit (basic helix-loop- helix transcription factor) HNRNPR 4.086 7.056 6.697 4.173 4.135 3.233 −5.905 0.0467047 heterogeneous nuclear ribonucleoprotein R PAIP1 4.904 7.555 6.730 4.173 4.490 3.701 −5.884 0.0276156 poly(A) binding protein interacting protein 1 C11 orf59 6.072 7.542 6.996 5.187 4.223 3.516 −5.879 0.0140184 chromosome 11 open reading frame 59 INSIG2 6.476 6.690 7.256 5.562 4.135 3.701 −5.875 0.0170769 insulin induced gene 2 TMEM130 8.090 4.788 4.248 2.233 2.233 3.737 −5.875 0.0257307 transmembrane protein 130 HK2 8.285 9.798 10.109 6.771 7.555 6.867 −5.871 0.0175477 hexokinase 2 GNL3 6.671 9.531 8.646 6.092 6.738 6.056 −5.870 0.0458860 guanine nucleotide binding protein-like 3 (nucleolar) FLJ36031 6.726 8.735 6.317 4.124 4.400 4.173 −5.870 0.0097348 No description AP3S1 3.792 7.053 6.211 3.838 3.659 2.648 −5.868 0.0387227 adaptor-related protein complex 3, sigma 1 subunit SERPINF1 7.193 10.266 7.539 4.988 4.764 5.618 −5.862 0.0130083 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 COLEC12 5.393 6.309 6.415 3.456 3.456 3.865 −5.854 0.0075719 collectin sub-family member 12 CPEB3 4.482 5.782 6.273 3.637 3.233 3.233 −5.852 0.0200406 cytoplasmic polyadenylation element binding protein 3 SRP68 4.826 7.401 7.317 4.854 2.970 3.516 −5.845 0.0222146 signal recognition particle 68 kDa RAB7A 10.249 11.845 11.316 8.769 9.065 8.581 −5.845 0.0134936 RAB7A, member RAS oncogene family BBS9 3.860 3.043 3.195 0.648 0.648 0.648 −5.844 0.0031310 Bardet-Biedl syndrome 9 AMIGO1 3.860 1.387 3.195 0.648 0.648 0.648 −5.844 0.0279442 adhesion molecule with Ig-like domain 1 POTEE 3.194 3.195 2.552 0.648 0.648 0.648 −5.837 0.0056378 POTE ankyrin domain family, member E B9D1 3.194 4.235 4.389 2.202 0.648 0.648 −5.837 0.0104579 B9 protein domain 1 TST 3.194 4.632 5.246 2.714 0.648 0.648 −5.837 0.0137508 thiosulfate sulfurtransferase (rhodanese) ACPL2 3.194 5.681 2.329 0.648 0.648 0.648 −5.837 0.0148648 acid phosphatase-like 2 C6orf26 3.194 3.871 3.881 0.648 0.648 2.370 −5.837 0.0155463 chromosome 6 open reading frame 26 MT1F 3.194 7.939 2.329 0.648 0.648 0.648 −5.837 0.0208052 metallothionein 1F ZNF775 3.194 3.452 1.649 0.648 0.648 0.648 −5.837 0.0216239 zinc finger protein 775 GSTO2 3.194 4.372 4.602 0.648 3.284 0.648 −5.837 0.0263172 glutathione S-transferase omega 2 PLEKHH2 5.816 8.526 8.009 5.526 5.464 5.429 −5.836 0.0434839 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 PRKCDBP 7.818 5.588 4.777 3.981 3.043 2.233 −5.835 0.0175726 protein kinase C, delta binding protein HSD3B7 7.579 8.670 6.819 5.246 5.034 4.670 −5.835 0.0094076 hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 7 RAB28 3.194 3.192 2.987 0.648 0.648 0.648 −5.830 0.0019172 RAB28, member RAS oncogene family MSTO1 3.194 3.192 1.245 0.648 0.648 0.648 −5.830 0.0355574 misato homolog 1 (Drosophila) STRAP 8.127 10.013 9.747 6.931 7.042 7.475 −5.809 0.0230541 serine/threonine kinase receptor associated protein PUM1 7.687 8.136 8.295 5.598 5.692 5.447 −5.806 0.0040309 pumilio homolog 1 (Drosophila) PGM1 5.982 7.245 7.302 4.711 4.709 3.694 −5.801 0.0125633 phosphoglucomutase 1 MARCKSL1 8.745 9.044 8.764 5.514 6.666 6.231 −5.790 0.0046582 MARCKS-like 1 NDNL2 5.322 7.105 6.889 4.575 3.686 3.737 −5.774 0.0157695 necdin-like 2 C10orf32 6.768 7.243 7.005 4.984 4.240 4.404 −5.769 0.0053681 chromosome 10 open reading frame 32 CTHRC1 7.436 8.140 4.928 5.003 3.686 4.908 −5.768 0.0399019 collagen triple helix repeat containing 1 ZNF549 4.423 5.898 4.852 2.625 1.648 3.370 −5.765 0.0154444 zinc finger protein 549 GBP2 5.422 6.840 7.284 3.848 3.978 4.756 −5.765 0.0183560 guanylate binding protein 2, interferon-inducible CMTM8 7.353 5.821 6.229 3.830 4.529 3.294 −5.763 0.0116170 CKLF-like MARVEL transmembrane domain containing 8 HIBADH 7.118 5.374 4.760 2.951 3.043 2.233 −5.761 0.0100073 3-hydroxyisobutyrate dehydrogenase PDK3 4.264 5.743 5.330 3.218 2.648 2.648 −5.757 0.0142728 pyruvate dehydrogenase kinase, isozyme 3 CDCA4 6.220 5.272 5.577 3.871 2.233 3.054 −5.746 0.0102263 cell division cycle associated 4 GPM6B 6.930 7.369 7.552 5.426 4.849 4.007 −5.734 0.0090936 glycoprotein M6B NEIL1 3.792 5.168 6.310 2.648 2.648 2.648 −5.733 0.0190381 nei endonuclease VIH-like 1 (E. coli)) XRN2 7.015 8.976 8.492 6.457 5.783 5.780 −5.731 0.0237009 5′-3′ exoribonuclease 2 CUTA 8.905 8.990 9.443 6.391 6.826 6.472 −5.726 0.0036627 cutA divalent cation tolerance homolog (E. coli) ARFIP1 5.235 6.898 7.113 4.385 4.385 3.516 −5.706 0.0196302 ADP-ribosylation factor interacting protein 1 COPB2 6.526 7.650 8.123 5.612 4.894 4.512 −5.699 0.0142326 coatomer protein complex, subunit beta 2 (beta prime) CYP51A1 7.161 8.890 8.400 6.382 5.413 5.009 −5.691 0.0144357 cytochrome P450, family 51, subfamily A, polypeptide 1 A2M 9.226 9.732 7.953 6.341 6.760 6.718 −5.688 0.0146035 alpha-2-macroglobulin TMEM64 8.289 9.700 8.730 6.144 6.091 7.199 −5.661 0.0135726 transmembrane protein 64 ZNF32 6.133 6.631 5.487 4.632 3.633 2.370 −5.657 0.0169210 zinc finger protein 32 BHLHE41 5.369 7.700 6.602 4.385 4.289 4.327 −4.840 0.0233633 basic helix-loop-helix family, member e41 KIAA0247 10.670 10.146 9.229 8.399 7.671 6.954 −4.840 0.0165224 KIAA0247 UPP1 10.908 9.557 11.190 8.915 8.329 8.117 −4.839 0.0219893 uridine phosphorylase 1 UBTD2 7.216 9.294 9.186 6.363 5.962 7.021 −4.835 0.0300919 ubiquitin domain containing 2 FAM129B 7.178 9.227 9.682 6.881 7.410 5.914 −4.831 0.0488759 family with sequence similarity 129, member B SLC17A5 6.137 7.185 6.244 4.854 4.879 3.865 −4.830 0.0215303 solute carrier family 17 (anion/sugar transporter), member 5 SCN4B 8.545 6.807 6.845 5.181 4.587 4.536 −4.827 0.0116260 sodium channel, voltage-gated, type IV, beta FAT1 7.748 9.952 9.499 6.490 7.682 7.039 −4.824 0.0368073 FAT tumor suppressor homolog 1 (Drosophila) AK3 7.804 7.360 6.967 5.767 4.646 5.091 −4.817 0.0130998 adenylate kinase 3 TMEM183B 4.647 7.172 6.138 3.871 3.871 3.966 −4.813 0.0310984 transmembrane protein 183B TRIP10 7.296 7.741 7.484 4.782 5.531 5.218 −4.812 0.0065889 thyroid hormone receptor interactor 10 TP53TG1 5.550 3.881 2.401 0.648 3.284 0.648 −4.812 0.0459317 TP53 target 1 (non-protein coding) CDKN2C 5.416 5.652 6.164 3.625 2.648 3.897 −4.811 0.0113965 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) CBX1 6.640 7.378 8.210 4.756 5.308 5.118 −4.791 0.0127581 chromobox homolog 1 PSMA4 6.017 8.161 7.815 5.901 5.303 4.670 −4.787 0.0345917 proteasome (prosome, macropain) subunit, alpha type, 4 RGS2 5.945 6.053 5.834 2.951 3.686 4.858 −4.787 0.0215574 regulator of G-protein signaling 2, 24 kDa GPAA1 7.816 7.413 7.757 5.761 5.155 5.206 −4.782 0.0065799 glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) AKIRIN1 8.894 8.784 8.501 6.632 6.384 6.529 −4.774 0.0052329 akirin 1 SPP1 5.293 5.709 5.949 3.233 3.694 3.233 −4.771 0.0073515 secreted phosphoprotein 1 C3orf58 5.977 6.298 6.215 3.961 4.240 3.648 −4.771 0.0066971 chromosome 3 open reading frame 58 TMC7 6.787 7.891 7.393 5.451 5.022 5.140 −4.769 0.0121709 transmembrane channel-like 7 ACLY 4.672 6.137 5.902 3.648 3.648 3.648 −4.769 0.0231948 ATP citrate lyase RPL10A 13.165 13.100 13.695 10.846 11.360 11.289 −4.769 0.0089841 ribosomal protein L10a PLEKHA3 6.594 8.766 8.387 6.135 6.078 6.345 −4.763 0.0490603 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 HIC1 11.438 7.730 8.577 6.269 6.328 6.656 −4.751 0.0239296 hypermethylated in cancer 1 TMEM205 5.982 7.887 6.866 5.290 4.618 3.897 −4.750 0.0209480 transmembrane protein 205 TMED2 9.676 11.149 10.815 8.902 8.419 7.697 −4.748 0.0189383 transmembrane emp24 domain trafficking protein 2 CASP7 4.895 6.405 5.740 4.579 2.648 2.648 −4.745 0.0227428 caspase 7, apoptosis-related cysteine peptidase MAP3K7IP2 6.010 8.042 7.761 5.653 5.517 5.145 −4.740 0.0395802 No description CPNE3 6.717 6.868 6.062 4.099 4.968 3.818 −4.736 0.0128322 copine III STK10 6.932 7.683 7.737 5.041 5.494 5.109 −4.735 0.0091179 serine/threonine kinase 10 SPIN4 4.744 5.051 4.892 2.648 2.648 2.648 −4.734 0.0038367 spindlin family, member 4 MYL12B 10.073 11.106 10.901 8.662 9.197 7.666 −4.720 0.0188211 myosin, light chain 12B, regulatory ANKRD46 5.976 5.634 4.916 3.737 3.686 2.233 −4.720 0.0174360 ankyrin repeat domain 46 ARPC5L 6.482 7.840 7.539 5.303 5.032 5.551 −4.708 0.0197931 actin related protein 2/3 complex, subunit 5-like FBXO21 7.248 7.892 7.660 5.657 5.239 5.109 −4.706 0.0074908 F-box protein 21 GYG1 8.087 8.244 6.554 6.013 5.807 4.837 −4.693 0.0268828 glycogenin 1 RHOJ 6.058 5.195 5.787 2.970 3.508 3.859 −4.675 0.0111747 ras homolog gene family, member J QARS 5.282 7.280 6.225 4.151 4.001 3.516 −4.672 0.0163296 glutaminyl-tRNA synthetase TTC7B 3.947 5.731 5.438 2.970 3.508 2.970 −4.669 0.0312336 tetratricopeptide repeat domain 7B CYC1 4.214 6.297 6.338 3.456 4.115 3.456 −4.668 0.0387865 cytochrome c-1 ATF1 6.645 6.245 6.813 4.424 4.611 3.516 −4.661 0.0091470 activating transcription factor 1 CHP 10.174 10.065 9.367 7.904 7.845 7.696 −4.659 0.0112655 No description MTDH 6.867 9.035 7.897 5.678 5.754 5.172 −4.655 0.0173279 metadherin USP22 9.631 10.672 10.401 8.454 7.912 8.017 −4.654 0.0135026 ubiquitin specific peptidase 22 CRMP1 6.735 4.866 4.793 2.648 2.648 3.897 −4.653 0.0214873 collapsin response mediator protein 1 MPST 6.368 6.975 7.102 5.167 4.151 4.481 −4.650 0.0119941 mercaptopyruvate sulfurtransferase PSMD4 7.568 8.050 7.920 6.536 5.351 5.407 −4.649 0.0160925 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 EIF3G 7.555 8.990 8.471 6.495 6.259 5.670 −4.631 0.0160835 eukaryotic translation initiation factor 3, subunit G CBR1 7.067 7.078 7.224 5.601 4.811 4.868 −4.628 0.0117029 carbonyl reductase 1 ELL 9.947 10.095 10.077 7.738 7.812 8.602 −4.625 0.0134603 elongation factor RNA polymerase II NKRF 6.023 6.481 6.057 3.494 3.852 5.367 −4.611 0.0291095 NFKB repressing factor SELENBP1 8.400 6.185 6.345 3.981 4.777 5.279 −4.608 0.0263678 selenium binding protein 1 LARP4 5.019 6.746 6.022 4.099 3.818 3.818 −4.606 0.0225674 La ribonucleoprotein domain family, member 4 SLC2A1 10.418 10.351 11.211 8.888 9.010 8.023 −4.598 0.0178631 solute carrier family 2 (facilitated glucose transporter), member 1 SLC25A11 4.525 5.244 5.693 4.417 3.043 2.233 −4.597 0.0389667 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 NRXN3 5.168 5.753 3.901 2.970 3.508 2.970 −4.587 0.0362652 neurexin 3 RPL13AP5 7.959 8.814 8.373 6.177 6.202 6.173 −4.582 0.0082125 ribosomal protein L13a pseudogene 5 CAT 6.688 6.266 5.855 4.610 3.467 4.071 −4.581 0.0129674 catalase FBN1 9.006 8.572 8.586 6.394 6.256 7.160 −4.568 0.0118367 fibrillin 1 NCRNA00095 7.193 9.056 9.060 6.869 6.426 6.836 −4.567 0.0459636 non-protein coding RNA 95 PCGF6 3.422 5.997 5.529 2.625 3.499 1.648 -5.650 0.0298707 polycomb group ring finger 6 TCEAL4 4.525 6.368 6.871 3.871 3.559 3.905 −5.645 0.0279692 transcription elongation factor A (SH)-like 4 ZNF581 6.103 7.163 7.472 4.667 4.168 4.857 −5.639 0.0122568 zinc finger protein 581 CD70 3.194 4.632 3.143 0.648 2.987 0.648 −5.636 0.0351629 CD70 molecule PSMA6 8.000 9.344 9.392 6.971 5.653 5.510 −5.620 0.0093806 proteasome (prosome, macropain) subunit, alpha type, 6 SFRP4 12.839 11.231 10.687 9.479 8.743 8.712 −5.609 0.0144627 secreted frizzled-related protein 4 RPL15 10.934 12.654 12.144 9.708 9.513 9.656 −5.609 0.0152454 ribosomal protein L15 TSPAN6 4.620 5.615 5.705 3.218 2.648 2.648 −5.608 0.0082395 tetraspanin 6 UBAC2 4.936 3.898 4.717 2.233 2.233 2.233 −5.594 0.0088884 UBA domain containing 2 LIMA1 5.938 7.799 5.713 3.456 5.011 3.456 −5.589 0.0216392 LIM domain and actin binding 1 DDAH1 8.379 7.700 6.862 5.394 5.220 4.778 −5.582 0.0099712 dimethylarginine dimethylaminohydrolase 1 GNPNAT1 4.086 7.377 5.713 3.233 3.694 3.233 −5.579 0.0322853 glucosamine-phosphate N-acetyltransferase 1 C1S 8.434 10.292 9.675 6.966 6.804 7.815 −5.567 0.0197542 complement component 1, s subcomponent GEFT 3.792 6.425 5.769 3.218 3.294 3.694 −5.560 0.0450139 No description FMO5 3.792 5.813 6.326 2.648 3.852 2.648 −5.554 0.0308981 flavin containing monooxygenase 5 ZDHHC4 6.713 6.089 5.516 4.276 3.043 3.508 −5.553 0.0108315 zinc finger, DHHC-type containing 4 NUPL1 5.960 8.135 7.693 5.663 5.212 4.507 −5.550 0.0294749 nucleoporin like 1 C22orf13 8.874 9.406 9.220 7.678 6.736 6.403 −5.544 0.0129265 chromosome 22 open reading frame 13 TRA2B 7.355 8.122 8.391 5.920 4.946 5.151 −5.544 0.0073605 transformer 2 beta homolog (Drosophila) TMEM184A 5.688 7.643 7.887 3.218 5.445 4.458 −5.543 0.0207192 transmembrane protein 184A TSC22D2 8.380 8.904 7.746 5.277 5.804 6.642 −5.536 0.0124101 TSC22 domain family, member 2 IGFBP7 9.173 11.325 7.793 7.053 5.635 6.704 −5.535 0.0199518 insulin-like growth factor binding protein 7 TMED3 7.705 7.726 6.980 5.897 4.490 5.237 −5.533 0.0143525 transmembrane emp24 protein transport domain containing 3 PDZRN3 6.135 7.870 6.348 3.881 3.827 4.670 −5.530 0.0112745 PDZ domain containing ring finger 3 C17orf85 4.872 6.851 6.338 3.808 4.383 3.456 −5.530 0.0248412 chromosome 17 open reading frame 85 IDH2 4.142 6.999 7.090 2.951 4.624 2.233 −5.525 0.0266458 Description HNRPDL 6.495 8.763 8.171 5.361 5.706 5.741 −5.523 0.0243296 heterogeneous nuclear ribonucleoprotein D-like PHC2 10.494 10.999 10.454 8.785 8.028 7.525 −5.522 0.0077702 polyhomeotic homolog 2 (Drosophila) MTCH2 3.947 5.711 5.435 2.970 2.970 2.970 −5.522 0.0229189 mitochondrial carrier homolog 2 (C. elegans) MGAT4B 7.903 8.382 8.816 6.352 5.872 5.815 −5.518 0.0078957 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N- acetylglucosaminyltransferase, isozyme B CLIC1 9.182 10.361 10.203 7.858 7.739 7.694 −5.515 0.0131594 chloride intracellular channel 1 C1orf122 5.739 7.166 6.505 3.351 4.043 4.262 −5.512 0.0093716 chromosome 1 open reading frame 122 DDIT4 7.951 5.926 5.679 3.218 3.659 3.694 −5.509 0.0097889 DNA-damage-inducible transcript 4 POLR1D 6.420 9.086 8.082 5.776 5.621 5.444 −5.507 0.0269542 polymerase (RNA) I polypeptide D, 16 kDa EPHB4 7.223 7.393 7.187 4.873 4.910 4.727 −5.503 0.0024440 EPH receptor B4 MBNL2 8.177 9.161 8.099 5.642 5.735 6.524 −5.489 0.0089335 muscleblind-like 2 (Drosophila) RAC1 11.568 11.897 11.492 9.441 9.179 8.660 −5.487 0.0043740 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rad) TMEM50A 6.274 6.661 6.689 4.688 3.818 4.146 −5.487 0.0075629 transmembrane protein 50A DCAF8 6.943 7.668 7.913 4.959 4.488 6.545 −5.485 0.0251047 DDB1 and CUL4 associated factor 8 PGF 5.600 5.966 5.647 3.442 2.970 3.516 −5.463 0.0045057 placental growth factor ZFYVE9 5.503 5.076 4.889 2.951 2.233 3.054 −5.461 0.0072246 zinc finger, FYVE domain containing 9 HHAT 4.860 4.097 3.379 1.648 1.648 1.648 −5.460 0.0093508 hedgehog acyltransferase PDE4A 7.009 6.933 5.763 4.561 3.648 4.264 −5.457 0.0117938 phosphodiesterase 4A. cAMP-specific BDKRB2 4.744 5.512 6.344 3.897 2.648 2.648 −5.451 0.0149730 bradykinin receptor B2 SNHG6 7.661 9.670 9.602 6.441 6.714 7.223 −5.451 0.0252884 small nucleolar RNA host gene 6 (non-protein coding) CYP27A1 3.619 6.116 6.074 3.670 3.467 2.233 −5.450 0.0407289 cytochrome P450, family 27, subfamily A, polypeptide 1 PPA1 6.280 9.481 8.044 5.747 5.600 5.561 −5.441 0.0321279 pyrophosphatase (inorganic) 1 DEF6 4.423 5.992 5.736 2.625 3.499 3.294 −5.432 0.0174090 differentially expressed in FDCP 6 homolog (mouse) C3orf59 6.454 7.730 4.845 3.961 4.600 4.013 −5.430 0.0353314 chromosome 3 open reading frame 59 F11R 6.220 8.124 7.913 5.377 5.690 4.950 −5.404 0.0262270 F11 receptor FBXL5 4.709 6.874 5.402 2.970 2.970 2.970 −5.395 0.0114555 F-box and leucine-rich repeat protein 5 WDR25 5.452 4.624 4.835 3.023 2.739 1.648 −5.386 0.0105168 WD repeat domain 25 RTN2 5.452 4.477 4.087 3.023 2.739 1.648 −5.386 0.0198111 reticulon 2 UBE2E2 8.331 7.788 7.019 6.239 4.624 4.590 −5.385 0.0144267 ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) C14orf1 5.322 4.575 5.379 2.951 2.233 2.233 −5.382 0.0056059 chromosome 14 open reading frame 1 CLEC3B 9.612 9.703 11.368 6.949 8.384 8.941 −5.378 0.0338631 C-type lectin domain family 3, member B SLC25A5 9.097 10.503 10.601 7.675 8.174 7.959 −5.376 0.0186069 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 PFN2 8.368 8.589 8.711 6.766 6.047 5.942 −5.376 0.0075900 profilin 2 TXNIP 6.967 9.337 9.046 6.619 5.686 6.688 −5.375 0.0341820 thioredoxin interacting protein CD2AP 5.346 6.216 6.063 3.637 3.694 3.233 −5.375 0.0076170 CD2-associated protein TMEM106B 6.535 7.125 7.636 4.902 4.653 4.701 −5.366 0.0082215 transmembrane protein 106B ANKRA2 3.422 4.072 4.314 1.648 1.648 1.648 −5.364 0.0075179 ankyrin repeat, family A (RFXANK-like), 2 ANO7 6.907 7.534 7.722 5.051 5.303 4.933 −5.350 0.0075359 anoctamin 7 ELK3 6.927 6.992 6.444 4.580 4.508 3.859 −5.349 0.0057127 ELK3, ETS-domain protein (SRF accessory protein 2) C16orf57 5.346 7.198 7.110 4.779 4.135 4.007 −5.347 0.0214111 chromosome 16 open reading frame 57 DAB2 8.218 10.388 10.550 7.613 7.612 8.131 −5.347 0.0420794 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) ARHGEF7 7.284 8.631 8.455 6.162 5.915 6.037 −5.347 0.0165827 Rho guanine nucleotide exchange factor (GEF) 7 NDUFV2 6.570 7.969 7.883 5.551 5.458 4.777 −5.344 0.0167248 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24 kDa ZNF669 6.320 6.802 6.144 3.682 4.385 4.317 −5.341 0.0081972 zinc finger protein 669 HABP4 5.552 5.719 5.120 3.218 2.648 3.303 −5.335 0.0061314 hyaluronan binding protein 4 SPTBN1 10.029 9.217 9.100 7.591 6.686 7.127 −5.331 0.0107775 spectrin, beta, non-erythrocytic 1 TWF2 6.565 5.122 6.216 4.151 3.559 3.054 −5.330 0.0140433 twinfilin, actin-binding protein, homolog 2 (Drosophila) TBL1XR1 8.867 8.637 8.309 6.191 5.946 6.453 −5.327 0.0049473 transducin (beta)-like 1 X-linked receptor 1 NDRG1 12.286 11.692 12.255 9.842 8.785 10.130 −5.324 0.0096004 N-myc downstream regulated 1 KIAA1522 6.220 7.998 8.519 4.653 6.111 5.093 −5.306 0.0270416 KIAA1522 TANC1 6.722 7.711 7.289 4.840 5.285 4.882 −5.303 0.0099206 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 VAPA 8.602 9.121 9.187 6.716 6.782 6.491 −5.295 0.0056946 VAMP (vesicle-associated membrane protein)-associated protein A, 33 kDa CBX3 6.226 8.096 8.375 5.082 5.970 5.441 −5.294 0.0311310 chromobox homolog 3 TAGLN2 9.473 11.280 10.668 8.720 8.266 8.162 −5.287 0.0223317 transgelin 2 PICALM 7.778 9.466 8.875 6.476 7.024 6.343 −5.275 0.0211830 phosphatidylinositol binding clathrin assembly protein MEST 8.068 7.668 6.523 4.042 6.479 5.270 −5.272 0.0340912 mesoderm specific transcript homolog (mouse) GSTK1 6.594 7.510 8.025 3.897 5.839 5.112 −5.271 0.0185404 glutathione S-transferase kappa 1 UROD 5.688 6.255 6.429 5.035 3.294 3.694 −5.256 0.0221064 uroporphyrinogen decarboxylase CRYZL1 3.422 5.191 4.041 1.648 1.648 1.648 −5.252 0.0103282 crystallin, zeta (quinone reductase)-like 1 MAP2K3 11.671 12.062 11.686 8.537 10.042 9.293 −5.252 0.0092683 mitogen-activated protein kinase kinase 3 SMARCD3 3.619 5.860 4.624 3.429 2.233 2.233 −5.245 0.0334139 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 ID2 3.619 5.989 4.624 2.233 2.233 3.508 −5.245 0.0355976 Description ANXA7 6.735 8.111 7.897 6.679 5.370 4.346 −5.238 0.0334319 annexin A7 LSM3 4.314 7.050 5.736 4.262 2.987 3.351 −5.224 0.0356697 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) SLC2A4 6.219 5.618 4.456 3.233 3.233 3.701 −5.223 0.0232308 solute carrier family 2 (facilitated glucose transporter), member 4 RASSF2 7.562 7.433 6.475 5.051 3.456 5.694 −5.214 0.0203560 Ras association (RalGDS/AF-6) domain family member 2 CTNND1 7.795 9.011 9.247 6.093 6.866 6.366 −5.210 0.0157196 catenin (cadherin-associated protein), delta 1 TM9SF3 9.175 10.230 10.334 7.954 7.714 6.918 −5.206 0.0122749 transmembrane 9 superfamily member 3 PIGK 8.258 6.871 5.240 4.492 4.611 4.453 −5.200 0.0305425 phosphatidylinositol glycan anchor biosynthesis, class K TAP1 8.312 8.348 7.276 5.936 4.791 6.286 −5.190 0.0165556 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) EPS8 6.785 8.972 8.072 6.416 5.696 5.523 −5.189 0.0295539 epidermal growth factor receptor pathway substrate 8 RPL32 12.723 13.973 13.998 11.002 11.306 11.623 −5.189 0.0139775 ribosomal protein L32 DPH5 6.547 5.409 6.543 3.202 4.174 3.557 −5.179 0.0097979 DPH5 homolog (S. cerevisiae) CYFIP2 5.322 5.772 4.753 2.951 2.233 3.905 −5.171 0.0177466 cytoplasmic FMR1 interacting protein 2 DPAGT1 4.709 6.196 6.049 3.442 3.827 2.970 −5.166 0.0168315 dolichyl-phosphate (UDP-N-acetylglucosamine) N- acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) ETV5 7.352 7.346 8.046 5.197 4.576 5.678 −5.163 0.0088350 ets variant 5 PROP 6.949 6.535 6.397 4.587 4.259 3.456 −5.141 0.0071976 prolylcarboxypeptidase (angiotensinase C) TNN 9.132 8.840 8.730 5.122 6.479 6.959 −5.138 0.0092932 tenascin N CMBL 4.008 3.423 4.351 1.648 1.648 1.648 −5.131 0.0077882 carboxymethylenebutenolidase homolog (Pseudomonas) GIMAP6 5.008 5.086 3.945 2.648 2.648 2.648 −5.131 0.0156135 GTPase, IMAP family member 6 CBFB 7.997 9.312 8.603 6.245 5.978 6.510 −5.126 0.0100731 core-binding factor, beta subunit VIM 13.008 15.405 12.193 10.652 10.596 11.747 −5.119 0.0284101 vimentin VPS35 6.537 7.533 8.164 5.180 5.352 4.405 −5.110 0.0136648 vacuolar protein sorting 35 homolog (S. cerevisiae) FBXL20 4.817 5.109 4.583 2.951 2.233 2.233 −5.098 0.0069931 F-box and leucine-rich repeat protein 20 LPHN3 7.536 4.583 3.211 2.233 2.233 2.233 −5.098 0.0275317 latrophilin 3 THBS2 9.034 11.015 10.779 8.666 7.741 8.279 −5.096 0.0296919 thrombospondin 2 CLPP 5.688 6.751 6.983 4.751 4.405 2.648 −5.086 0.0179366 CIpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)) EIF3H 8.682 9.415 9.847 6.607 7.177 7.070 −5.082 0.0096600 eukaryotic translation initiation factor 3, subunit H GPX7 5.952 6.031 5.082 4.081 2.739 2.752 −5.073 0.0119019 glutathione peroxidase 7 S1PR3 5.532 7.494 6.896 5.151 3.859 4.536 −5.072 0.0270076 sphingosine-1-phosphate receptor 3 EIF3M 4.264 7.273 7.367 4.017 5.026 2.648 −5.067 0.0447768 eukaryotic translation initiation factor 3, subunit M STX3 5.683 7.576 8.177 5.053 5.836 4.969 −5.067 0.0494672 syntaxin 3 TNFSF9 7.991 7.409 6.881 5.070 3.899 5.749 −5.059 0.0141154 tumor necrosis factor (ligand) superfamily, member 9 KLF4 8.552 10.278 8.854 6.495 6.516 7.767 −5.059 0.0209910 Kruppel-like factor 4 (gut) DPP4 5.204 5.830 2.987 3.351 0.648 3.043 −5.057 0.0481723 dipeptidyl-peptidase 4 BGN 11.207 11.651 8.508 6.920 6.306 9.314 −5.054 0.0282818 biglycan COMP 3.792 8.519 4.986 2.648 2.648 3.694 −5.054 0.0396357 cartilage oligomeric matrix protein THY1 9.053 8.901 7.411 5.796 6.398 6.720 −5.040 0.0218035 Thy-1 cell surface antigen SLC15A4 6.259 6.988 6.484 4.655 4.585 3.818 −5.038 0.0108808 solute carrier family 15, member 4 HECTD1 5.386 7.520 7.697 5.189 4.555 5.225 −5.033 0.0457432 HECT domain containing 1 RPS27L 8.453 8.955 8.828 7.498 6.356 6.125 −5.020 0.0175206 ribosomal protein S27-like OPN3 4.969 7.125 6.601 3.442 4.797 4.042 −5.020 0.0300205 opsin 3 ABLIM1 7.737 8.444 7.479 5.812 6.116 5.081 −5.020 0.0135366 actin binding LIM protein 1 LMCD1 8.478 8.126 6.986 5.691 6.151 5.210 −5.018 0.0180406 LIM and cysteine-rich domains 1 PAIP2 8.523 9.711 7.936 6.770 6.082 6.196 −5.017 0.0150471 poly(A) binding protein interacting protein 2 PPFIBP1 7.147 8.545 7.360 5.036 5.811 5.028 −5.009 0.0127338 PTPRF interacting protein, binding protein 1 (liprin beta 1) IGFBP3 8.376 8.465 8.183 6.507 5.859 5.866 −5.008 0.0069210 insulin-like growth factor binding protein 3 DYNLT3 5.999 7.872 7.474 5.548 3.694 4.054 −5.006 0.0162132 dynein, light chain, Tetex-type 3 CRIP1 4.620 8.749 4.971 2.648 2.648 2.648 −5.003 0.0164801 cysteine-rich protein 1 (intestinal) ZNF281 4.264 5.746 6.486 4.165 2.648 3.303 −4.999 0.0320912 zinc finger protein 281 STAU1 7.554 8.213 8.121 5.234 5.996 5.637 −4.994 0.0077231 staufen, RNA binding protein, homolog 1 (Drosophila) DUSP4 5.047 7.350 6.965 3.648 5.030 4.013 −4.993 0.0299047 dual specificity phosphatase 4 SPOCK1 7.683 6.434 5.535 4.501 4.115 3.456 −4.990 0.0159248 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 DDB1 8.857 9.921 9.997 7.853 7.515 6.538 −4.990 0.0158742 damage-specific DNA binding protein 1, 127 kDa ETS2 8.823 10.662 8.965 7.659 6.504 6.773 −4.990 0.0161473 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) ECH1 7.127 6.505 6.126 3.808 4.853 3.865 −4.986 0.0107865 enoyl CoA hydratase 1, peroxisomal PAM 7.010 8.371 8.151 6.054 5.229 5.262 −4.984 0.0139144 peptidylglycine alpha-amidating monooxygenase GMPR 4.423 5.056 4.624 2.625 2.739 1.648 −4.983 0.0100551 guanosine monophosphate reductase NFYC 5.904 6.810 7.164 4.397 3.978 4.848 −4.982 0.0145057 nuclear transcription factor Y, gamma HOPX 8.532 5.783 5.472 3.278 3.467 5.279 −4.980 0.0322541 HOP homeobox TMEM101 7.032 7.005 7.206 6.103 4.717 3.859 −4.978 0.0237438 transmembrane protein 101 NFIL3 7.849 9.441 9.373 6.203 5.654 7.126 −4.977 0.0148468 nuclear factor, interleukin 3 regulated COL15A1 9.137 7.542 7.424 6.299 5.784 5.109 −4.977 0.0196842 collagen, type XV, alpha 1 RILPL2 4.142 7.007 5.592 3.278 2.233 3.508 −4.976 0.0229009 Rab interacting lysosomal protein-like 2 MFAP3 8.742 7.829 7.763 6.427 5.794 5.215 −4.975 0.0135276 microfibrillar-associated protein 3 IL33 6.169 7.249 5.562 4.935 3.648 3.648 −4.973 0.0214964 interleukin 33 ADCY3 7.330 9.122 7.772 5.911 5.460 5.112 −4.965 0.0118458 adenylate cyclase 3 MTND2 12.858 14.115 13.694 11.547 11.803 10.492 −4.963 0.0163386 No description TC2N 4.331 6.111 6.550 3.648 4.240 3.648 −4.959 0.0449709 tandem C2 domains, nuclear LGMN 8.273 8.959 8.602 6.425 5.967 6.638 −4.943 0.0081196 legumain PSMD8 8.568 10.496 10.041 8.046 7.737 6.492 −4.939 0.0247490 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 AGRN 6.981 7.471 7.990 4.678 5.852 4.859 −4.936 0.0123428 agrin SETD7 5.151 6.881 6.650 4.549 4.349 4.349 −4.930 0.0330652 SET domain containing (lysine methyltransferase) 7 RPIA 5.169 7.372 6.676 4.377 4.453 4.174 −4.920 0.0273605 ribose 5-phosphate isomerase A CCPG1 6.397 6.361 6.543 4.099 3.818 4.377 −4.917 0.0046492 cell cycle progression 1 SLC2A4RG 7.638 6.653 6.764 4.357 4.876 5.005 −4.910 0.0108135 SLC2A4 regulator C6orf168 4.264 4.944 5.016 2.648 2.648 2.648 −4.910 0.0099622 chromosome 6 open reading frame 168 PTH1R 6.017 3.859 5.266 2.970 2.970 2.970 −4.910 0.0259088 parathyroid hormone 1 receptor LRRN4CL 5.786 6.409 5.979 3.456 4.115 3.865 −4.904 0.0080523 LRRN4 C-terminal like C7orf29 4.647 3.192 4.972 3.351 2.353 0.648 −4.903 0.0417133 chromosome 7 open reading frame 29 TRAM1 9.311 9.345 8.801 8.048 7.019 6.156 −4.898 0.0235657 translocation associated membrane protein 1 DCUN1D3 8.532 9.133 8.698 6.406 5.564 8.041 −4.898 0.0304052 DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) LUC7L2 7.971 8.499 8.457 6.207 6.046 5.911 −4.896 0.0059574 LUC7-like 2 (S. cerevisiae) GPN1 4.525 4.554 3.184 2.233 2.233 2.233 −4.896 0.0252974 GPN-loop GTPase 1 ISM1 4.525 4.586 2.820 2.233 2.233 2.233 −4.896 0.0397965 isthmin 1 homolog (zebrafish) SELPLG 4.525 5.585 3.170 2.233 2.233 3.054 −4.896 0.0413293 selectin P ligand SS18 8.251 8.827 8.980 7.086 5.960 6.078 −4.894 0.0115421 synovial sarcoma translocation, chromosome 18 CHST14 6.312 5.963 5.522 3.848 3.978 3.233 −4.886 0.0099532 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 ULK3 4.620 6.184 6.591 4.273 3.659 3.897 −4.877 0.0361404 unc-51-like kinase 3 (C. elegans) IFFO2 8.418 8.588 8.761 6.016 7.537 6.305 −4.867 0.0226506 intermediate filament family orphan 2 NFKBIL1 5.644 5.904 6.333 4.052 3.686 2.233 −4.859 0.0110936 nuclear factor of kappa light polypeptide gene enhancer in B- cells inhibitor-like 1 TP53RK 4.904 7.155 6.551 4.737 4.271 4.054 −4.859 0.0423373 TP53 regulating kinase USP33 6.506 7.772 7.393 5.494 4.653 4.862 −4.852 0.0144808 ubiquitin specific peptidase 33 HIGD2A 6.495 7.588 7.919 5.472 5.015 5.309 −4.851 0.0179906 HIG1 hypoxia inducible domain family, member 2A FTO 7.394 7.265 6.532 5.894 4.141 4.988 −4.847 0.0241667 fat mass and obesity associated CBX4 7.088 7.039 7.195 4.017 4.812 6.390 −4.844 0.0313078 chromobox homolog 4 B3GALNT1 4.312 4.509 4.508 2.233 2.233 2.233 −4.840 0.0037258 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) DOPEY2 7.832 8.751 9.018 6.476 5.576 6.487 −4.840 0.0123698 dopey family member 2 CLU 7.000 9.281 6.843 4.653 6.262 5.452 −4.563 0.0336336 clusterin CDYL 6.202 6.982 6.492 4.868 4.294 4.013 −4.561 0.0116939 chromodomain protein, Y-like PPP2CA 9.159 9.986 9.926 7.496 7.719 7.797 −4.559 0.0126783 protein phosphatase 2, catalytic subunit, alpha isozyme SMAD7 6.891 9.079 7.304 5.115 4.871 5.644 −4.559 0.0159636 SMAD family member 7 SERPINH1 12.425 12.685 12.048 10.239 9.538 10.692 −4.552 0.0119761 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) SEC22C 5.475 6.435 5.701 4.722 2.970 3.516 −4.548 0.0225834 SEC22 vesicle trafficking protein homolog C (S. cerevisiae) EMILIN2 6.171 7.356 7.091 5.119 4.906 4.901 −4.548 0.0193598 elastin microfibril interfacer 2 NAAA 4.817 5.122 4.417 3.535 2.233 2.233 −4.545 0.0178076 N-acylethanolamine acid amidase C19orf20 5.683 5.570 5.759 4.878 3.499 1.648 −4.543 0.0314367 chromosome 19 open reading frame 20 MRPL22 4.734 4.950 3.832 3.023 1.648 1.648 −4.542 0.0148073 mitochondrial ribosomal protein L22 C6orf108 6.770 5.472 6.334 4.664 4.151 3.054 −4.541 0.0199005 chromosome 6 open reading frame 108 RPS5 11.941 13.370 12.737 10.554 10.977 10.542 −4.540 0.0197293 ribosomal protein S5 IRAK2 8.103 9.276 7.684 7.078 5.510 5.920 −4.539 0.0242000 interleukin-1 receptor-associated kinase 2 ATP1B2 8.801 7.247 6.567 6.220 4.385 5.857 −4.538 0.0414270 ATPase, Na+/K+ transporting, beta 2 polypeptide RCN1 8.423 9.873 9.511 7.650 7.329 7.157 −4.538 0.0243913 reticulocalbin 1, EF-hand calcium binding domain LOC728661 6.392 6.932 7.492 5.254 4.141 5.311 −4.535 0.0211199 No description PRDX2 7.424 7.907 7.261 5.974 5.244 4.360 −4.532 0.0138451 peroxiredoxin 2 C2orf28 7.949 7.550 7.226 5.773 5.561 4.071 −4.517 0.0140523 chromosome 2 open reading frame 28 CYBA 7.555 7.888 7.783 5.610 5.824 5.279 −4.509 0.0070471 cytochrome b-245, alpha polypeptide IAH1 5.264 4.797 4.536 2.625 4.174 1.648 −4.507 0.0347553 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) EEF1B2 6.470 6.999 6.751 5.113 4.273 4.581 −4.501 0.0115990 eukaryotic translation elongation factor 1 beta 2 RBM24 4.936 5.213 4.769 2.951 3.043 2.233 −4.500 0.0088974 RNA binding motif protein 24 PMP22 10.730 11.016 9.588 8.303 8.561 8.742 −4.499 0.0237099 peripheral myelin protein 22 GLUL 8.763 10.521 9.851 7.682 7.318 7.916 −4.497 0.0220704 glutamate-ammonia ligase DAB2IP 6.138 6.813 6.740 3.970 5.221 4.516 −4.493 0.0188600 DAB2 interacting protein FAF2 5.614 7.035 6.612 4.868 4.007 3.648 −4.492 0.0174666 Fas associated factor family member 2 KCNS3 3.422 3.832 3.814 1.648 1.648 1.648 −4.487 0.0074638 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 GMCL1L 5.042 3.814 3.832 3.557 1.648 1.648 −4.487 0.0399650 germ cell-less homolog 1 (Drosophila)-like TPM4 7.962 10.442 9.373 7.336 7.208 5.800 −4.486 0.0238693 tropomyosin 4 BRF2 4.264 5.737 6.438 4.273 2.648 2.648 −4.486 0.0281501 BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like SPIN1 7.689 7.552 7.328 6.136 4.767 5.387 −4.484 0.0157515 spindlin 1 ARSB 6.517 7.318 6.309 4.587 4.405 4.146 −4.477 0.0086513 arylsulfatase B UBE2D1 6.510 8.205 8.599 5.293 5.517 6.437 −4.474 0.0339393 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) TRADD 4.314 4.647 5.444 3.081 3.284 0.648 −4.471 0.0254707 TNFRSF1 A-associated via death domain DGCR2 6.958 7.625 7.716 6.077 5.465 4.486 −4.470 0.0205397 DiGeorge syndrome critical region gene 2 PIK3R2 6.167 5.733 6.024 3.233 3.978 4.007 −4.469 0.0087671 phosphoinositide-3-kinase, regulatory subunit 2 (beta) IDH1 6.547 5.453 5.183 3.023 3.805 3.929 −4.468 0.0181674 Description MRPS30 6.418 6.688 6.535 4.376 5.256 4.104 −4.467 0.0167518 mitochondrial ribosomal protein S30 S100A10 8.526 11.277 11.095 7.405 9.119 7.655 −4.463 0.0417556 S100 calcium binding protein A10 ATG16L1 5.076 6.881 6.630 4.690 4.474 4.179 −4.458 0.0398728 ATG16 autophagy related 16-like 1 (S. cerevisiae) YIPF5 6.985 7.482 7.317 5.327 4.899 5.083 −4.455 0.0073924 Yip1 domain family, member 5 EFEMP2 10.199 7.986 8.731 7.683 6.358 6.575 −4.455 0.0322451 EGF-containing fibulin-like extracellular matrix protein 2 FJX1 6.256 7.176 6.031 3.218 5.023 4.581 −4.447 0.0224010 four jointed box 1 (Drosophila) CYB5B 7.160 7.770 7.403 5.551 5.618 4.382 −4.446 0.0131504 cytochrome b5 type B (outer mitochondrial membrane) RADIL 6.425 5.420 5.863 4.273 2.648 4.199 −4.444 0.0209820 Ras association and DIL domains SFRS2 9.856 11.408 11.199 8.519 9.236 9.047 −4.444 0.0283830 No description CANX 10.974 11.566 11.478 10.281 9.206 8.826 −4.430 0.0246492 calnexin ADSS 5.076 6.133 6.819 3.988 3.508 4.042 −4.424 0.0188510 adenylosuccinate synthase RPL10 14.704 14.394 14.745 12.246 12.601 12.559 −4.423 0.0065168 ribosomal protein L10 C11orf73 5.861 5.863 4.652 3.718 3.294 2.648 −4.423 0.0159546 chromosome 11 open reading frame 73 SLC27A1 7.367 7.299 7.422 5.277 5.278 4.007 −4.418 0.0085757 solute carrier family 27 (fatty acid transporter), member 1 KIAA0040 7.177 7.083 5.556 4.905 4.672 5.033 −4.418 0.0369002 KIAA0040 BTG2 11.114 9.902 8.886 7.761 7.175 7.910 −4.410 0.0196211 BTG family, member 2 DCTN3 7.283 7.096 6.526 4.956 5.681 3.508 −4.408 0.0226159 dynactin 3 (p22) LIF 8.986 11.390 10.953 8.815 8.906 7.628 −4.403 0.0435158 leukemia inhibitory factor (cholinergic differentiation factor) RSU1 7.912 7.477 7.050 5.498 5.774 4.796 −4.402 0.0141244 Ras suppressor protein 1 IFRD2 6.167 8.585 8.547 5.489 6.448 5.444 −4.398 0.0461938 interferon-related developmental regulator 2 CHRDL1 7.347 7.501 6.272 5.136 4.135 6.104 −4.398 0.0368842 chordin-like 1 MFF 4.977 5.761 6.132 3.997 3.456 3.456 −4.392 0.0175026 mitochondrial fission factor MRPS34 7.188 7.238 6.783 5.355 5.053 4.262 −4.391 0.0120849 mitochondrial ribosomal protein S34 COMMD10 3.194 1.477 2.781 0.648 0.648 0.648 −4.384 0.0298617 COMM domain containing 10 IGDCC4 7.007 4.944 5.587 3.456 3.456 4.409 −4.382 0.0290298 immunoglobulin superfamily, DCC subclass, member 4 SCPEP1 4.142 7.421 4.364 2.233 2.233 2.233 -4.379 0.0162222 serine carboxypeptidase 1 ZBTB41 5.899 5.570 5.570 3.442 4.385 2.970 −4.372 0.0167858 zinc finger and BTB domain containing 41 CMPK2 5.683 5.671 4.115 3.557 2.739 3.294 −4.365 0.0275497 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial SH2B3 9.833 9.224 8.476 7.707 6.450 6.472 −4.365 0.0166915 SH2B adaptor protein 3 NXT2 3.619 5.641 5.658 3.535 3.467 2.233 −4.355 0.0467948 nuclear transport factor 2-like export factor 2 GPR116 7.731 6.702 5.608 5.083 4.377 4.580 −4.354 0.0299449 G protein-coupled receptor 116 TFPI 9.010 11.614 11.216 9.492 7.081 7.492 −4.353 0.0293660 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) MAG 11 6.554 5.582 5.713 4.293 4.433 3.456 −4.351 0.0232399 membrane associated guanylate kinase, WW and PDZ domain containing 1 FBLN1 12.034 12.031 10.631 9.066 9.634 9.915 −4.344 0.0231386 fibulin 1 CCS 5.109 4.294 4.352 2.233 2.233 2.233 −4.343 0.0065529 copper chaperone for superoxide dismutase SNX2 5.042 5.945 6.343 3.830 4.692 2.752 −4.332 0.0310083 sorting nexin 2 PLSCR3 7.637 7.236 7.514 5.838 5.400 4.007 −4.329 0.0149085 phospholipid scramblase 3 RARB 5.346 6.711 5.730 3.951 3.694 3.233 −4.325 0.0129445 retinoic acid receptor, beta TBC1D5 8.350 6.945 6.886 6.238 4.659 6.007 −4.325 0.0478007 TBC1 domain family, member 5 SERPING1 7.904 9.121 7.715 5.792 5.718 5.873 −4.320 0.0100821 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 CMC1 3.194 2.758 2.593 0.648 0.648 0.648 −4.317 0.0063220 COX assembly mitochondrial protein homolog (S. cerevisiae) ROBO1 4.214 6.263 5.566 3.456 3.456 3.865 −4.317 0.0421820 roundabout, axon guidance receptor, homolog 1 (Drosophila) C11 orf60 4.826 5.506 5.080 2.970 2.970 2.970 −4.315 0.0074347 No description GGT5 10.639 8.482 7.486 6.373 5.977 6.474 −4.313 0.0234194 gamma-glutamyltransferase 5 CCDC80 11.038 10.260 10.755 8.152 8.250 9.728 −4.312 0.0260620 coiled-coil domain containing 80 GOLGA4 5.431 6.497 6.215 4.108 4.108 4.382 −4.308 0.0192752 golgin A4 KLHL13 3.792 5.996 4.755 2.648 2.648 2.648 −4.308 0.0224960 kelch-like 13 (Drosophila) RRP1B 6.182 8.123 7.238 4.603 5.206 5.132 −4.307 0.0202139 ribosomal RNA processing 1 homolog B (S. cerevisiae) NUP133 4.086 5.616 5.742 3.637 3.233 3.233 −4.305 0.0351913 nucleoporin 133 kDa C4orf46 7.695 8.035 6.941 5.346 4.837 6.349 −4.300 0.0235040 chromosome 4 open reading frame 46 BDKRB1 9.692 7.974 7.983 7.039 6.188 5.869 −4.300 0.0242333 bradykinin receptor B1 PSME1 9.912 9.668 9.383 8.316 7.291 7.279 −4.299 0.0161154 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) C3orf38 5.633 6.142 5.074 4.957 2.970 3.516 −4.298 0.0430458 chromosome 3 open reading frame 38 GAS1 6.773 5.966 4.735 4.501 3.859 3.865 −4.288 0.0435865 growth arrest-specific 1 MUSTN1 4.734 5.384 4.839 2.625 2.739 3.294 −4.286 0.0113341 musculoskeletal, embryonic nuclear protein 1 C8orf58 4.008 3.692 3.748 1.648 1.648 1.648 −4.286 0.0047643 chromosome 8 open reading frame 58 TMEM59 11.208 11.091 11.072 9.110 8.912 9.003 −4.281 0.0047283 transmembrane protein 59 NEK7 7.736 8.273 8.339 6.073 6.047 6.242 −4.278 0.0104939 NIMA (never in mitosis gene a)-related kinase 7 PARD3 4.378 5.208 5.064 2.970 2.970 2.970 −4.269 0.0142908 par-3 partitioning defective 3 homolog (C. elegans) ADAM12 8.698 7.204 6.999 4.905 5.538 5.944 −4.268 0.0223158 ADAM metallopeptidase domain 12 FAM36A 6.381 7.907 7.694 5.086 5.813 4.987 −4.268 0.0237633 family with sequence similarity 36, member A PREB 5.688 5.945 6.849 4.350 3.852 3.694 −4.265 0.0133626 prolactin regulatory element binding SLC25A39 3.947 6.062 5.062 3.682 2.970 2.970 −4.264 0.0408787 solute carrier family 25, member 39 TCF15 8.215 4.751 5.648 4.376 3.247 3.557 −4.262 0.0332385 transcription factor 15 (basic helix-loop-helix) HERC4 4.672 5.875 6.052 3.961 3.648 3.648 −4.261 0.0281778 hect domain and RLD 4 SH3BGRL3 9.266 9.841 10.338 8.019 8.249 6.606 −4.256 0.0209730 SH3 domain binding glutamic acid-rich protein like 3 ADD3 6.568 6.973 6.034 4.225 4.264 4.885 −4.249 0.0140614 adducin 3 (gamma) SEMA3C 6.048 6.240 4.451 3.961 4.007 3.648 −4.248 0.0424475 sema domain, immunoglobulin domain (ig), short basic domain, secreted, (semaphorin) 3C B4GALT5 8.619 10.093 9.268 7.123 7.183 7.529 −4.241 0.0183241 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 FHL1 7.744 8.518 6.728 5.906 4.646 6.002 −4.235 0.0256600 four and a half LIM domains 1 LSM2 7.580 6.911 7.482 6.065 5.060 4.830 −4.232 0.0190291 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) JUP 8.744 9.865 9.969 7.144 8.646 6.666 −4.223 0.0318867 junction plakoglobin CD44 12.394 13.237 12.364 10.607 10.286 10.448 −4.222 0.0096364 CD44 molecule (Indian blood group) RNF2 7.159 7.844 6.732 4.655 5.202 5.301 −4.219 0.0125362 ring finger protein 2 H2AFX 7.460 7.940 8.588 5.522 5.863 6.107 −4.218 0.0126693 H2A histone family, member X MXRA7 10.309 10.391 9.298 8.315 7.910 7.860 −4.216 0.0177376 matrix-remodelling associated 7 MAGEH1 5.821 6.435 6.158 4.929 2.233 4.082 −4.215 0.0241036 melanoma antigen family H, 1 PIK3CD 5.339 6.874 7.206 5.132 4.467 4.436 −4.213 0.0393785 phosphoinositide-3-kinase, catalytic, delta polypeptide PROS1 5.769 7.022 5.360 3.718 3.659 3.694 −4.211 0.0132107 protein S (alpha) COPZ2 7.926 5.903 5.631 3.830 4.174 3.557 −4.211 0.0154860 coatomer protein complex, subunit zeta 2 GNPTG 4.817 5.282 5.607 3.535 3.043 3.054 −4.204 0.0125452 N-acetylglucosamine-1-phosphate transferase, gamma subunit TRAPPC4 4.008 5.416 4.811 3.714 2.739 1.648 −4.204 0.0322062 trafficking protein particle complex 4 ARMCX1 6.679 7.394 8.034 5.323 4.988 5.939 −4.200 0.0234603 armadillo repeat containing, X-linked 1 MAP4K5 7.340 8.971 8.818 6.540 6.748 6.865 −4.198 0.0418977 mitogen-activated protein kinase kinase kinase kinase 5 C11 orf24 5.938 7.375 6.252 5.306 4.259 3.456 −4.196 0.0251463 chromosome 11 open reading frame 24 LARGE 6.081 7.034 6.177 4.342 4.108 4.108 −4.196 0.0095130 like-glycosyltransferase ZFR 6.426 7.820 7.989 5.921 5.288 5.270 −4.195 0.0272981 zinc finger RNA binding protein MLST8 4.312 4.302 4.588 3.278 2.233 2.233 −4.194 0.0220163 MTOR associated protein, LST8 homolog (S. cerevisiae) INPP1 6.322 4.930 5.202 2.233 4.254 3.508 −4.193 0.0278742 inositol polyphosphate-1 -phosphatase C3orf31 3.194 1.649 2.714 0.648 0.648 0.648 −4.187 0.0249508 chromosome 3 open reading frame 31 RPPH1 5.204 2.714 3.881 3.351 0.648 0.648 −4.187 0.0410173 ribonuclease P RNA component H1 GBP1 6.735 7.258 7.401 4.262 5.196 6.173 −4.178 0.0300385 guanylate binding protein 1. interferon-inducible. 67 kDa GCLM 7.691 8.979 9.543 6.878 7.326 6.916 −4.178 0.0421910 glutamate-cysteine ligase, modifier subunit SAE1 8.119 8.060 7.929 6.949 5.783 5.997 −4.177 0.0233029 SUMO1 activating enzyme subunit 1 FOSB 15.170 13.757 13.523 11.461 11.814 12.852 −4.176 0.0263081 FBJ murine osteosarcoma viral oncogene homolog B DCAF12 6.280 7.891 7.344 4.954 5.248 5.829 −4.175 0.0315969 DDB1 and CUL4 associated factor 12 SMARCD1 4.331 6.208 6.434 3.648 4.372 3.648 −4.175 0.0489993 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 FKBP7 7.978 6.892 6.552 4.492 4.508 5.981 −4.169 0.0246943 FK506 binding protein 7 FLNB 5.775 7.425 8.015 4.891 5.957 4.736 −4.165 0.0457570 filamin B, beta EDF1 8.386 9.240 9.575 7.519 7.355 5.963 −4.158 0.0236919 endothelial differentiation-related factor 1 UBE2G1 5.691 7.304 7.150 5.088 5.004 5.248 −4.157 0.0454797 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) MFHAS1 7.275 7.034 6.222 4.912 4.871 5.221 −4.154 0.0198250 malignant fibrous histiocytoma amplified sequence 1 HLA-DPA1 8.797 7.409 6.580 5.357 5.170 6.420 −4.146 0.0398929 major histocompatibility complex, class II, DP alpha 1 OSBPL8 5.978 7.936 7.282 5.581 4.932 5.232 −4.142 0.0369501 oxysterol binding protein-like 8 MORC3 6.145 7.770 7.140 5.722 4.678 4.724 −4.135 0.0272593 MORC family CW-type zinc finger 3 IQCK 3.619 4.281 4.692 2.233 2.233 2.233 −4.134 0.0152877 IQ motif containing K TBC1D20 8.409 9.355 9.372 7.328 6.761 6.908 −4.123 0.0151414 TBC1 domain family, member 20 SLC35B3 5.503 4.276 5.437 3.535 2.233 3.054 −4.120 0.0205924 solute carrier family 35, member B3 PALM 6.851 6.133 4.498 4.091 3.456 4.141 −4.120 0.0389847 paralemmin KIAA1715 7.269 7.208 7.287 5.607 5.228 4.997 −4.117 0.0102173 KIAA1715 TNFRSF11B 3.422 5.540 5.082 3.023 3.499 1.648 −4.115 0.0461473 tumor necrosis factor receptor superfamily, member 11b C6orf106 7.504 9.257 9.553 7.315 7.216 6.587 −4.115 0.0492454 chromosome 6 open reading frame 106 GOLM1 8.426 7.833 7.456 5.395 6.208 6.387 −4.112 0.0215906 golgi membrane protein 1 TP53INP1 5.690 6.333 6.894 4.859 3.456 4.293 −4.111 0.0208641 tumor protein p53 inducible nuclear protein 1 CPEB2 7.696 9.416 7.500 5.529 5.657 6.669 −4.110 0.0238832 cytoplasmic polyadenylation element binding protein 2 C2CD2 7.060 8.178 7.546 6.103 5.693 5.021 −4.110 0.0205744 C2 calcium-dependent domain containing 2 TAOK1 5.047 5.685 6.085 3.961 3.648 3.648 −4.103 0.0185750 TAO kinase 1 ST6GALNAC6 7.264 7.912 5.699 5.177 5.228 5.345 −4.102 0.0493438 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N- acetylgalactosaminide alpha-2,6-sialyltransferase 6 UBE2N 5.809 7.670 6.953 4.457 5.182 4.917 −4.101 0.0280801 ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) C7orf30 6.202 6.638 6.853 5.133 4.602 3.043 −4.101 0.0198679 chromosome 7 open reading frame 30 PSAP 10.066 11.226 10.791 8.830 8.237 8.757 −4.095 0.0151844 prosaposin INSR 6.133 7.711 7.499 5.678 5.237 5.127 −4.093 0.0340308 insulin receptor ZBTB20 6.920 5.666 4.643 3.637 3.233 4.508 −4.081 0.0398423 zinc finger and BTB domain containing 20 DYRK1A 8.939 9.881 9.433 7.566 7.406 7.210 −4.078 0.0129903 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A ITM2B 11.201 11.172 9.972 8.985 8.803 9.173 −4.076 0.0257979 integral membrane protein 2B ANTXR1 8.547 7.572 6.978 5.499 5.545 5.889 −4.075 0.0194062 anthrax toxin receptor 1 PJA2 8.480 8.287 8.290 6.884 6.085 6.265 −4.072 0.0133958 praja ring finger 2 PITPNA 6.701 7.415 7.681 5.655 5.107 5.009 −4.071 0.0157376 phosphatidylinositol transfer protein, alpha METTL12 4.008 4.764 5.058 1.648 2.739 3.557 −4.070 0.0310173 methyltransferase like 12 POLR2C 5.282 7.213 6.966 5.192 4.385 3.859 −4.059 0.0340218 polymerase (RNA) II (DNA directed) polypeptide C, 33 kDa HEXIM1 7.809 8.727 7.706 5.617 5.788 6.788 −4.057 0.0213896 hexamethylene bis-acetamide inducible 1 ARL8B 7.685 9.183 9.488 6.882 7.163 7.261 −4.056 0.0433889 ADP-ribosylation factor-like 8B SCHIP1 6.886 6.961 6.927 4.907 6.255 4.179 −4.055 0.0375553 schwannomin interacting protein 1 ATG7 5.474 6.424 6.581 4.621 3.456 3.456 −4.052 0.0147913 ATG7 autophagy related 7 homolog (S. cerevisiae) ANTXR2 6.892 6.533 6.894 4.515 4.664 5.181 −4.052 0.0117542 anthrax toxin receptor 2 CBX8 4.423 4.536 4.757 2.625 2.739 1.648 −4.051 0.0111026 chromobox homolog 8 PTTG1IP 6.426 7.904 6.985 5.886 5.376 4.299 −4.051 0.0333244 pituitary tumor-transforming 1 interacting protein BMPR2 7.696 7.416 6.905 5.518 5.319 5.402 −4.041 0.0132537 bone morphogenetic protein receptor, type II (serine/threonine kinase) COBRA1 7.354 6.783 7.111 5.453 5.097 4.623 −4.040 0.0130354 cofactor of BRCA1 CNNM4 5.832 6.775 6.566 4.099 3.818 5.145 −4.040 0.0210541 cyclin M4 FLJ43663 3.792 5.487 4.661 2.648 2.648 2.648 −4.035 0.0221584 No description TEX10 7.077 8.391 8.902 5.235 6.383 6.701 −4.025 0.0322943 testis expressed 10 TCEB2 7.165 8.506 8.176 6.498 6.245 4.590 −4.023 0.0268600 transcription elongation factor B (SIH), polypeptide 2 (18 kDa, elongin B) TSPAN4 7.986 7.238 7.237 5.962 3.827 5.981 −4.014 0.0264010 tetraspanin 4 TNPO2 8.681 8.640 8.960 6.843 6.316 6.956 -4.013 0.0101092 transportin 2 CEBPG 6.753 8.102 7.386 5.051 5.650 5.382 −4.011 0.0174000 CCAAT/enhancer binding protein (C/EBP), gamma MFGE8 11.262 11.000 11.056 9.149 9.259 8.780 −4.009 0.0082541 milk fat globule-EGF factor 8 protein SRP14 6.422 7.034 6.671 5.453 3.508 4.670 −4.003 0.0213272 signal recognition particle 14 kDa (homologous Alu RNA binding protein) NAA30 4.086 6.012 5.233 3.233 3.233 3.233 −3.999 0.0304350 N(alpha)-acetyltransferase 30, NatO catalytic subunit KRR1 5.982 6.856 7.181 4.667 5.023 4.857 −3.999 0.0226596 KRR1, small subunit (SSU) processome component, homolog (yeast) BBS1 4.969 4.956 5.748 2.970 3.508 2.970 −3.996 0.0127740 Bardet-Biedl syndrome 1 NCOA7 7.596 8.741 9.014 6.501 6.743 6.875 −3.995 0.0300295 nuclear receptor coactivator 7 NUDT11 3.619 5.557 5.486 2.951 3.559 2.233 −3.994 0.0372870 nudix (nucleoside diphosphate linked moiety X)-type motif 11 FAM150B 4.008 3.645 3.640 1.648 1.648 1.648 −3.991 0.0059664 family with sequence similarity 150, member B ZNF213 4.423 3.645 5.110 3.557 1.648 1.648 −3.990 0.0316634 zinc finger protein 213 CEBPZ 6.128 7.509 7.132 5.137 5.859 3.818 −3.987 0.0357106 CCAAT/enhancer binding protein (C/EBP), zeta ZFAND1 5.956 6.514 5.690 4.315 4.015 3.694 −3.987 0.0128863 zinc finger, AN1-type domain 1 C10orf75 5.503 4.902 5.244 3.278 2.233 3.508 −3.986 0.0139373 No description NCL 9.396 10.743 9.451 7.402 7.911 7.908 −3.985 0.0173508 nucleolin LSM1 5.781 6.010 6.613 4.017 4.017 3.929 −3.980 0.0092315 LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) CDC42 10.625 10.974 10.991 9.297 8.869 8.634 −3.975 0.0126873 cell division cycle 42 (GTP binding protein, 25 kDa) CSRP1 11.817 10.780 11.434 8.789 10.112 9.068 −3.975 0.0220565 cysteine and glycine-rich protein 1 MPV17 5.572 6.061 6.781 4.624 3.868 4.071 −3.973 0.0201161 MpV17 mitochondrial inner membrane protein ARVCF 4.895 4.637 3.494 2.648 2.648 2.648 −3.969 0.0316059 armadillo repeat gene deleted in velocardiofacial syndrome CKAP4 11.076 10.513 10.806 10.076 8.749 8.525 −3.967 0.0384766 cytoskeleton-associated protein 4 MLLT11 4.972 5.894 6.229 3.662 2.987 4.262 −3.959 0.0217744 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 GNS 9.402 9.824 8.858 7.839 6.249 7.430 −3.958 0.0188960 glucosamine (N-acetyl)-6-sulfatase PGLS 7.914 6.785 7.585 5.601 5.823 4.975 −3.957 0.0198860 6-phosphogluconolactonase SLC2A3 12.429 10.812 10.874 9.040 8.830 10.355 −3.951 0.0359490 solute carrier family 2 (facilitated glucose transporter), member 3 HTRA1 6.081 8.944 5.793 4.099 3.818 4.507 −3.950 0.0210360 HtrA serine peptidase 1 COL12A1 7.244 8.533 8.230 5.852 5.727 6.552 −3.946 0.0224780 collagen, type XII, alpha 1 GNG2 7.700 6.153 5.280 4.173 3.694 5.118 −3.944 0.0382159 guanine nucleotide binding protein (G protein), gamma 2 FLJ45079 5.042 6.691 5.997 4.017 3.247 4.376 −3.944 0.0253154 No description WDR12 4.008 4.308 3.627 1.648 2.739 1.648 −3.942 0.0192662 WD repeat domain 12 SLC41A2 5.524 3.627 3.538 2.625 1.648 1.648 −3.942 0.0242922 solute carrier family 41, member 2 MYO M2 4.008 3.627 3.832 1.648 1.648 3.294 −3.942 0.0474215 myomesin (M-protein) 2, 165 kDa CNIH 4.524 6.088 5.494 3.682 2.970 3.516 −3.940 0.0236198 cornichon homolog (Drosophila) SERPINE1 10.229 11.288 11.136 9.978 8.252 9.117 −3.937 0.0395560 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 CLDND1 9.838 9.773 9.651 7.650 7.798 8.019 −3.932 0.0088101 claudin domain containing 1 PPP1CB 9.537 10.541 10.025 8.259 8.051 7.659 −3.931 0.0143248 protein phosphatase 1, catalytic subunit, beta isozyme ELOVL5 9.633 10.725 10.416 7.931 7.849 8.751 −3.929 0.0169362 ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) SMARCAL1 5.644 4.543 4.629 3.670 2.233 3.508 −3.927 0.0358534 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 APTX 3.947 5.005 5.416 3.442 2.970 2.970 −3.927 0.0361993 aprataxin ZHX1 6.599 6.501 6.092 4.681 3.456 4.528 −3.926 0.0141334 zinc fingers and homeoboxes 1 FUCA2 5.620 7.062 5.698 4.280 4.240 3.648 −3.922 0.0206873 fucosidase, alpha-L-2, plasma ACSS1 4.620 4.719 5.945 2.648 3.659 3.303 −3.922 0.0273896 acyl-CoA synthetase short-chain family member 1 DPYSL2 9.550 9.475 8.999 7.733 6.131 7.504 −3.920 0.0171435 dihydropyrimidinase-like 2 UCK2 7.183 9.537 8.103 5.213 7.098 6.381 −3.919 0.0426867 uridine-cytidine kinase 2 C20orf11 7.682 8.766 8.750 6.796 6.329 6.290 −3.918 0.0197023 chromosome 20 open reading frame 11 GOLPH3L 4.524 5.486 6.302 4.302 2.970 3.516 −3.918 0.0380620 golgi phosphoprotein 3-like TMEM14A 6.453 5.851 5.109 2.233 4.294 4.483 −3.916 0.0337002 transmembrane protein 14A RAP2B 8.433 9.940 9.922 6.942 7.970 7.271 −3.915 0.0251553 RAP2B, member of RAS oncogene family NEK5 6.072 8.119 6.482 4.830 4.529 4.104 −3.911 0.0174846 NIMA (never in mitosis gene a)-related kinase 5 RWDD2B 5.255 4.201 4.393 3.429 2.233 2.233 −3.911 0.0239068 RWD domain containing 2B RRBP1 7.322 7.517 7.837 5.553 5.333 5.871 −3.908 0.0113570 ribosome binding protein 1 homolog 180 kDa (dog) FOXA1 3.792 4.615 5.377 3.218 2.648 2.648 −3.908 0.0325452 forkhead box A1 TMEM51 6.590 7.963 7.586 4.981 5.621 5.880 −3.904 0.0259435 transmembrane protein 51 ASPH 11.182 10.306 10.040 9.032 9.218 8.066 −3.902 0.0339213 aspartate beta-hydroxylase HSPA5 10.115 12.209 12.325 10.361 8.799 8.527 −3.901 0.0307983 heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa) NOV 5.861 7.042 4.181 2.648 4.273 3.897 −3.899 0.0457785 nephroblastoma overexpressed gene ZFX 6.345 7.578 7.114 5.576 5.103 5.151 −3.898 0.0268114 zinc finger protein, X-linked MTCO3 16.809 16.093 16.318 14.473 14.847 14.026 −3.894 0.0155130 No description SYTL2 6.741 5.193 5.096 3.637 3.233 3.233 −3.889 0.0158055 synaptotagmin-like 2 GHDC 6.208 5.191 5.584 3.637 3.233 3.701 −3.885 0.0120253 GH3 domain containing TRAPPC6B 4.482 5.773 5.191 3.233 3.233 3.233 −3.883 0.0191331 trafficking protein particle complex 6B MARVELD2 4.264 5.874 6.054 3.494 4.097 3.303 −3.883 0.0413605 MARVEL domain containing 2 MAF 10.326 9.289 9.629 7.672 7.287 9.064 −3.882 0.0433979 v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) SIRT6 4.936 5.422 5.821 4.457 3.467 2.233 −3.877 0.0321778 sirtuin 6 TMEM50B 5.230 6.625 6.751 4.799 4.618 4.049 −3.870 0.0384121 transmembrane protein 50B LOC552889 8.246 8.566 8.708 6.917 6.294 6.514 −3.869 0.0126444 No description FBXW4 3.792 5.668 5.548 3.718 2.648 2.648 −3.863 0.0335012 F-box and WD repeat domain containing 4 NUPRI 8.997 9.198 9.377 7.623 7.150 7.048 −3.861 0.0123199 nuclear protein, transcriptional regulator, 1 PPAP2A 6.906 7.559 6.146 4.957 4.734 5.156 −3.861 0.0216572 phosphatidic acid phosphatase type 2A KIAA0090 5.293 6.574 6.121 3.637 4.324 4.173 −3.860 0.0207282 KIAA0090 NUCB1 8.622 8.043 7.042 6.194 5.904 6.094 −3.860 0.0268919 nucleobindin 1 IGFBP4 10.737 11.068 10.676 8.790 8.159 9.208 −3.858 0.0124801 insulin-like growth factor binding protein 4 EHD2 12.903 11.224 10.190 10.039 9.277 8.466 −3.856 0.0370555 EH-domain containing 2 C9orf21 8.812 9.093 7.915 7.142 6.784 6.866 −3.852 0.0285640 chromosome 9 open reading frame 21 STK32B 3.947 4.915 5.045 2.970 2.970 2.970 −3.849 0.0274256 serine/threonine kinase 32B DFNA5 6.312 2.401 2.593 0.648 0.648 0.648 −3.849 0.0217341 deafness, autosomal dominant 5 SMAD1 7.501 7.267 6.678 5.421 5.323 5.009 −3.847 0.0154354 SMAD family member 1 RAB5C 7.930 9.222 8.863 7.101 6.920 6.871 −3.846 0.0283158 RAB5C, member RAS oncogene family LIMCH1 5.751 6.571 6.791 3.808 4.383 5.339 −3.845 0.0304808 LIM and calponin homology domains 1 NCOA4 9.035 9.188 8.717 7.195 7.246 6.632 −3.842 0.0125723 nuclear receptor coactivator 4 FGF13 4.860 2.926 3.588 1.648 1.648 1.648 −3.837 0.0210000 fibroblast growth factor 13 SH3BP5 6.824 8.445 8.029 6.133 5.573 6.093 −3.826 0.0301168 SH3-domain binding protein 5 (BTK-associated) PKDCC 8.182 6.550 7.757 5.821 5.005 5.873 −3.825 0.0283518 protein kinase domain containing, cytoplasmic homolog (mouse) ARF3 10.191 9.701 9.752 8.257 8.061 7.201 −3.822 0.0152274 ADP-ribosylation factor 3 PPP1R2 5.768 6.944 6.645 4.713 4.784 3.897 −3.817 0.0206645 protein phosphatase 1. regulatory (inhibitor) subunit 2 COQ2 4.647 3.881 1.962 2.714 0.648 0.648 −3.817 0.0478146 coenzyme Q2 homolog, prenyltransferase (yeast) KLHL12 3.792 5.421 5.331 3.494 2.648 2.648 −3.804 0.0309494 kelch-like 12 (Drosophila) SCCPDH 5.572 5.322 5.462 3.535 3.958 3.054 −3.801 0.0142998 saccharopine dehydrogenase (putative) TRA2A 7.302 9.000 8.799 6.618 6.354 7.078 −3.792 0.0439789 transformer 2 alpha homolog (Drosophila) PRR3 4.969 5.803 4.557 3.881 2.970 2.970 −3.792 0.0273127 proline rich 3 NUDT5 5.204 5.222 5.053 4.529 3.284 0.648 −3.785 0.0430867 nudix (nucleoside diphosphate linked moiety X)-type motif 5 ALDH7A1 6.190 6.158 5.100 4.026 4.271 3.701 −3.782 0.0240191 aldehyde dehydrogenase 7 family, member A1 RNF146 6.949 7.443 7.554 5.525 5.005 5.651 −3.778 0.0146797 ring finger protein 146 C4orf34 4.657 4.150 3.676 2.233 2.233 2.233 −3.776 0.0150062 chromosome 4 open reading frame 34 RBM7 6.594 6.989 7.489 5.072 4.097 5.881 −3.776 0.0257556 RNA binding motif protein 7 NTRK2 6.500 7.240 6.223 4.349 5.119 4.584 −3.774 0.0177286 neurotrophic tyrosine kinase, receptor, type 2 LMAN1 5.594 7.252 7.376 5.461 4.108 4.382 −3.772 0.0293432 lectin, mannose-binding, 1 FAM24B 3.194 4.283 2.552 0.648 0.648 2.370 −3.766 0.0311449 family with sequence similarity 24, member B RHOT1 5.901 5.607 5.727 4.640 3.694 3.701 −3.765 0.0235837 ras homolog gene family, member T1 SETD3 6.141 5.800 5.144 3.951 4.135 3.233 −3.760 0.0203650 SET domain containing 3 TSPYL4 3.792 5.213 4.863 2.648 2.648 3.303 −3.758 0.0315470 TSPY-like4 NAALADL2 4.142 4.160 4.048 2.233 2.233 2.233 −3.754 0.0069030 N-acetylated alpha-linked acidic dipeptidase-like 2 PCDHB5 4.142 4.225 3.881 2.233 2.233 2.233 −3.754 0.0099802 protocadherin beta 5 SERPINF2 4.657 4.142 3.861 2.233 2.233 2.233 −3.754 0.0116350 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 BATF3 4.142 5.002 4.767 2.233 3.467 2.233 −3.754 0.0221425 basic leucine zipper transcription factor, ATF-like 3 HMGB2 4.142 5.798 5.917 2.951 2.233 4.071 −3.754 0.0288537 high-mobility group box 2 TAF12 4.142 5.045 4.188 3.737 2.233 2.233 −3.754 0.0414360 TAF12 RNA polymerase II, TATA box binding protein (TBP)- associated factor, 20 kDa CISH 4.142 4.383 2.850 2.233 2.233 2.233 −3.754 0.0451990 cytokine inducible SH2-containing protein ZBTB38 6.142 6.220 6.807 5.244 4.233 4.233 −3.754 0.0240281 zinc finger and BTB domain containing 38 RDH10 5.142 6.962 5.368 3.233 3.233 5.159 −3.754 0.0477681 retinol dehydrogenase 10 (all-trans) H6PD 7.264 7.528 6.557 6.214 5.167 4.648 −3.754 0.0352801 hexose-6-phosphate dehydrogenase (glucose 1- dehydrogenase) PSMD7 6.833 8.439 7.912 6.895 6.004 4.681 −3.752 0.0487137 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 SLC9A3R2 6.291 5.604 5.428 4.240 4.385 2.970 −3.747 0.0267934 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 SRPK1 6.534 7.544 7.995 5.638 5.808 4.804 −3.747 0.0260114 SRSF protein kinase 1 KCNE4 9.418 11.308 10.322 8.421 8.411 9.003 −3.734 0.0403705 potassium voltage-gated channel, Isk-related family, member 4 FAM76A 4.378 5.942 5.111 4.042 2.970 2.970 −3.734 0.0350146 family with sequence similarity 76. member A CA12 7.768 7.732 8.784 6.886 6.813 5.202 −3.726 0.0420205 carbonic anhydraseXII SFRS2B 6.217 7.499 6.831 5.473 4.561 4.935 −3.722 0.0252614 No description MRPL9 3.422 5.456 3.544 1.648 1.648 1.648 −3.721 0.0155220 mitochondrial ribosomal protein L9 GJC2 5.452 4.839 5.652 3.557 3.499 3.557 −3.721 0.0174575 gap junction protein, gamma 2, 47 kDa MRPS23 3.619 5.544 4.950 3.429 2.233 3.054 -3.721 0.0432808 mitochondrial ribosomal protein S23 SLCO4A1 5.751 6.826 6.969 4.681 4.259 5.074 −3.719 0.0255532 solute carrier organic anion transporter family, member 4A1 NDUFA11 8.721 8.836 8.148 7.432 6.830 5.606 −3.708 0.0284870 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7 kDa STS 5.293 4.908 5.124 3.233 3.233 3.233 −3.708 0.0096690 steroid sulfatase (microsomal), isozyme S SPAG7 7.233 8.041 7.611 5.656 6.151 5.558 −3.707 0.0178915 sperm associated antigen 7 IL13RA1 7.703 7.781 7.346 5.457 6.273 5.506 −3.704 0.0171241 interleukin 13 receptor, alpha 1 PRKACB 7.142 5.352 5.706 4.256 3.818 3.818 −3.701 0.0223636 protein kinase, cAMP-dependent, catalytic, beta PKN1 8.027 6.999 7.629 6.533 4.361 5.742 −3.698 0.0328718 protein kinase N1 RBP7 7.580 6.378 5.576 4.017 5.463 4.493 −3.692 0.0434700 retinol binding protein 7, cellular KIAA1430 5.904 6.748 7.067 5.382 4.864 3.970 −3.691 0.0312988 KIAA1430 FAM8A1 6.245 6.164 4.858 4.280 4.294 4.013 −3.690 0.0433744 family with sequence similarity 8, member A1 N4BP2L1 5.661 4.610 5.399 3.682 2.970 3.516 −3.689 0.0227282 NEDD4 binding protein 2-like 1 CAP2 5.255 4.115 3.581 2.233 2.233 2.233 −3.686 0.0193834 CAP, adenylate cyclase-associated protein, 2 (yeast) SGCE 7.791 8.436 6.863 5.196 5.189 6.555 −3.685 0.0276246 sarcoglycan, epsilon VEGFA 13.253 12.011 11.804 9.923 10.388 11.331 −3.683 0.0379449 vascular endothelial growth factor A GHITM 5.730 7.640 7.718 5.837 4.264 4.516 −3.683 0.0321189 growth hormone inducible transmembrane protein TIMELESS 5.173 4.722 5.471 3.218 3.294 3.303 −3.678 0.0143615 timeless homolog (Drosophila) FPGS 6.472 7.513 7.831 5.958 5.358 4.733 −3.663 0.0273355 folylpolyglutamate synthase TMX1 6.663 6.691 7.164 4.820 4.587 5.553 −3.660 0.0192017 thioredoxin-related transmembrane protein 1 FSCN1 9.852 8.192 8.611 6.320 6.953 7.776 −3.660 0.0372073 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) MYO1B 7.816 8.103 8.340 6.549 6.191 5.945 −3.660 0.0146659 myosin IB PRR23A 8.172 8.501 8.745 6.124 6.630 7.472 −3.659 0.0294000 proline rich 23A NAA38 6.133 6.679 6.981 5.870 4.728 4.262 −3.657 0.0437445 N(alpha)-acetyltransferase 38, NatC auxiliary subunit SLC25A28 6.315 8.181 7.171 5.629 5.302 5.285 −3.654 0.0331220 solute carrier family 25, member 28 DPYD 5.846 5.305 6.232 3.233 3.978 4.650 −3.650 0.0280024 dihydropyrimidine dehydrogenase IFI6 11.376 10.183 10.594 9.050 8.318 8.830 −3.643 0.0187227 interferon, alpha-inducible protein 6 ATP6V1F 6.895 8.466 8.048 6.572 6.184 5.396 −3.640 0.0395345 ATPase, H+ transporting, lysosomal 14 kDa, V1 subunit F C11 or95 6.967 6.659 6.324 4.496 4.462 5.262 −3.636 0.0168690 chromosome 11 open reading frame 95 HSD17B14 6.133 5.213 5.452 3.662 3.633 3.351 −3.635 0.0124440 hydroxysteroid (17-beta) dehydrogenase 14 RFK 4.264 4.818 4.510 2.648 2.648 2.648 −3.635 0.0112087 riboflavin kinase ANXA4 7.463 6.036 6.097 5.057 4.174 5.023 −3.635 0.0351449 annexin A4 MFN1 3.792 5.642 4.510 2.648 2.648 3.303 −3.633 0.0374035 mitofusin 1 ASCC2 4.525 6.166 4.915 2.951 3.686 3.054 −3.633 0.0255442 activating signal cointegrator 1 complex subunit 2 SIX4 5.404 6.123 5.699 3.648 3.648 4.264 −3.626 0.0162735 SIX homeobox 4 COPS7A 5.107 6.488 5.717 4.515 3.859 3.456 −3.625 0.0295449 COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) SLC25A34 6.118 7.776 7.310 5.453 4.659 5.467 −3.622 0.0306340 solute carrier family 25, member 34 HMGCS1 6.198 7.021 7.294 5.438 4.865 4.694 −3.620 0.0234811 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) CTSB 9.929 10.637 11.449 9.594 8.535 8.388 −3.617 0.0343983 cathepsin B UXT 7.460 8.807 8.417 6.952 5.977 6.388 −3.617 0.0304440 ubiquitously-expressed transcript FAM18B 3.194 3.810 4.934 3.081 2.353 0.648 −3.613 0.0492059 No description RBP1 6.320 5.841 5.117 3.988 4.001 3.516 −3.612 0.0193425 retinol binding protein 1, cellular CHSY1 10.405 10.193 9.687 8.343 8.135 8.526 −3.607 0.0177778 chondroitin sulfate synthase 1 RUSC2 6.208 7.495 7.525 5.674 5.086 5.644 −3.606 0.0409487 RUN and SH3 domain containing 2 NR3C1 7.529 7.789 7.416 5.833 5.093 5.939 −3.606 0.0144537 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) PUM2 7.704 8.349 8.553 5.881 6.152 6.704 −3.602 0.0169452 pumilio homolog 2 (Drosophila) CFL1 12.625 12.901 12.668 10.819 11.353 10.370 −3.602 0.0165646 cofilin 1 (non-muscle) LIMS2 8.052 6.627 6.636 4.778 5.553 5.430 −3.601 0.0299886 LIM and senescent cell antigen-like domains 2 LRP1 12.146 11.071 11.708 9.978 9.114 10.300 −3.595 0.0268024 low density lipoprotein receptor-related protein 1 NMNAT2 3.947 5.673 5.137 2.970 3.827 2.970 −3.595 0.0463969 nicotinamide nucleotide adenylyltransferase 2 CCDC120 7.352 8.367 8.238 6.393 6.537 5.453 −3.594 0.0257827 coiled-coil domain containing 120 NOTCH1 7.986 8.091 7.350 5.506 5.716 6.875 −3.591 0.0307414 notch 1 PDGFC 4.378 5.341 5.359 3.442 2.970 3.516 −3.588 0.0262548 platelet derived growth factor C CCDC34 6.444 5.499 5.378 3.535 4.523 4.071 −3.586 0.0303373 coiled-coil domain containing 34 C19orf62 4.817 6.254 6.760 4.748 4.413 3.054 −3.582 0.0468406 chromosome 19 open reading frame 62 RSAD2 5.708 7.197 6.596 4.756 4.490 4.848 −3.580 0.0270686 radical S-adenosyl methionine domain containing 2 ACVR1 8.692 8.141 8.988 7.761 6.852 6.227 −3.579 0.0401334 activin A receptor, type I PFKFB3 10.900 11.092 10.364 8.524 8.788 9.353 −3.579 0.0175969 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 NFS1 5.109 6.133 5.163 4.276 4.294 3.054 −3.579 0.0470957 NFS1 nitrogen fixation 1 homolog (S. cerevisiae) CDK11A 3.422 5.540 5.340 2.625 3.704 1.648 −3.570 0.0402360 cyclin-dependent kinase 11A TFPI2 5.587 6.742 5.358 4.017 3.659 3.752 −3.567 0.0171151 tissue factor pathway inhibitor 2 CBX6 5.289 6.350 5.930 4.681 3.859 3.456 −3.562 0.0263262 chromobox homolog 6 OBFC1 5.968 6.243 6.566 5.214 4.411 4.042 −3.559 0.0282492 oligonucleotide/oligosaccharide-binding fold containing 1 CAV1 11.402 11.375 9.824 9.551 9.544 7.994 −3.559 0.0456253 caveolin 1, caveolae protein, 22 kDa COL5A1 11.883 9.199 9.090 7.369 7.282 8.055 −3.557 0.0260711 collagen, type V, alpha 1 ITGA7 8.251 7.768 6.515 5.937 5.235 6.098 −3.557 0.0391789 integrin, alpha 7 STAT1 7.798 7.641 7.829 7.000 5.968 5.769 −3.555 0.0407040 signal transducer and activator of transcription 1,91 kDa DOLPP1 5.173 5.488 5.571 4.390 3.659 2.648 −3.554 0.0295719 dolichyl pyrophosphate phosphatase 1 ZCCHC7 5.160 5.106 4.916 3.278 3.467 2.233 −3.550 0.0155955 zinc finger, CCHC domain containing 7 COL7A1 4.948 5.476 6.115 3.648 4.007 3.648 −3.550 0.0246763 collagen, type VII, alpha 1 SCNN1B 3.422 3.475 4.429 1.648 1.648 1.648 −3.547 0.0121397 sodium channel, nonvoltage-gated 1, beta CNOT10 3.619 4.719 4.778 2.951 2.233 2.233 −3.546 0.0236468 CCR4-NOT transcription complex, subunit 10 PRKAA1 4.214 5.289 5.633 3.808 3.456 3.456 −3.544 0.0497251 protein kinase. AMP-activated, alpha 1 catalytic subunit C17of101 4.525 5.360 4.641 3.535 2.233 3.508 −3.543 0.0335879 chromosome 17 open reading frame 101 YPEL3 6.545 7.998 8.486 6.356 5.199 6.174 −3.543 0.0469196 yippee-like 3 (Drosophila) CHCHD3 6.770 7.213 6.475 5.628 4.946 4.351 −3.542 0.0244565 coiled-coil-helix-coiled-coil-helix domain containing 3 PRINS 5.644 5.252 6.070 3.429 4.294 3.508 −3.539 0.0187726 psoriasis associated RNA induced by stress (non-protein coding) PM20D2 5.047 6.125 6.371 4.362 4.007 4.303 −3.535 0.0353626 peptidase M20 domain containing 2 EHD4 4.619 6.191 5.458 3.637 3.694 3.233 −3.534 0.0248641 EH-domain containing 4 PGAP2 4.709 4.791 5.937 2.970 2.970 2.970 −3.532 0.0135456 post-GPI attachment to proteins 2 FAM3B 4.647 4.901 6.198 3.081 4.602 0.648 −3.532 0.0421730 family with sequence similarity 3, member B CASC4 10.130 9.494 9.065 8.213 7.642 7.674 −3.530 0.0257161 cancer susceptibility candidate 4 CCDC152 10.040 7.718 8.005 6.186 6.101 7.632 −3.529 0.0495650 coiled-coil domain containing 152 SFRS3 9.698 10.957 10.520 9.140 8.641 8.652 −3.525 0.0367255 No description C6orf192 5.503 5.888 5.952 3.278 5.030 4.071 −3.525 0.0419678 chromosome 6 open reading frame 192 SF1 11.276 12.211 11.883 9.708 10.212 10.066 −3.523 0.0202471 splicing factor 1 EN1 5.341 6.002 5.314 3.557 3.499 3.557 −3.520 0.0109154 engrailed homeobox 1 NBL1 7.036 8.704 7.369 6.889 5.304 5.445 −3.519 0.0454319 neuroblastoma, suppression of tumorigenicity 1 C5orf32 8.745 9.438 9.450 7.636 7.428 7.294 −3.516 0.0184842 chromosome 5 open reading frame 32 ETNK2 5.552 4.713 4.646 3.718 3.739 2.648 −3.514 0.0404842 ethanolamine kinase 2 LPPR2 8.824 8.642 9.014 7.157 6.974 7.012 −3.510 0.0121078 No description CD200 5.007 6.242 5.044 3.233 3.233 3.233 −3.507 0.0134049 CD200 molecule ZAK 9.957 9.022 8.113 7.847 7.212 7.018 −3.506 0.0459227 No description C4orf3 10.365 10.049 9.959 8.664 8.243 7.383 −3.499 0.0168135 chromosome 4 open reading frame 3 BLMH 6.818 7.375 6.094 5.328 4.289 5.083 −3.495 0.0268205 bleomycin hydrolase TSPAN7 7.233 5.656 5.021 3.494 3.852 4.579 −3.491 0.0354541 tetraspanin 7 JAK1 7.020 8.486 7.562 6.183 5.217 6.651 −3.490 0.0472551 Janus kinase 1 EIF3E 5.915 6.684 6.832 4.581 5.029 4.820 −3.489 0.0252704 eukaryotic translation initiation factor 3, subunit E SSPN 8.319 5.604 5.451 3.648 4.007 4.303 −3.488 0.0269009 sarcospan (Kras oncogene-associated gene) CASD1 7.053 5.975 5.578 5.200 4.135 4.173 −3.487 0.0416745 CAS1 domain containing 1 PSPC1 4.708 5.917 5.410 3.456 4.115 3.456 −3.487 0.0318021 paraspeckle component 1 MTND6 13.009 12.338 12.201 10.828 11.028 10.400 −3.486 0.0213626 No description BTG1 10.912 11.456 11.607 9.362 9.113 10.474 −3.480 0.0357667 B-cell translocation gene 1, anti-proliferative NRAS 8.203 7.486 7.136 6.404 6.212 4.293 −3.478 0.0374811 neuroblastoma RAS viral (v-ras) oncogene homolog UBQLN2 8.225 8.864 8.431 7.020 6.793 6.427 −3.477 0.0185161 ubiquilin 2 CRLF3 5.525 7.535 6.882 5.086 4.339 5.290 −3.473 0.0465924 cytokine receptor-like factor 3 WDR60 3.619 4.485 5.074 3.278 2.233 2.233 −3.473 0.0332295 WD repeat domain 60 ZFP36L2 11.829 12.143 11.720 9.913 10.034 10.944 −3.473 0.0311130 zinc finger protein 36. C3H type-like 2 TIMM10 7.081 7.298 7.859 5.502 6.232 4.830 −3.472 0.0247581 translocase of inner mitochondrial membrane 10 homolog (yeast) ABT1 6.348 7.236 7.506 5.837 5.441 4.007 −3.471 0.0337459 activator of basal transcription 1 STAC 5.042 3.441 4.281 1.648 3.704 1.648 −3.464 0.0470617 SH3 and cysteine rich domain EDEM2 4.969 4.508 5.235 3.442 2.970 2.970 −3.464 0.0184260 ER degradation enhancer, mannosidase alpha-like 2 TPPP3 8.553 7.982 7.295 5.109 6.190 7.222 −3.462 0.0489903 tubulin polymerization-promoting protein family member 3 C1orf103 3.422 5.595 3.437 1.648 1.648 1.648 −3.456 0.0173598 chromosome 1 open reading frame 103 PCMTD2 6.654 6.153 6.160 5.097 4.372 4.013 −3.454 0.0215726 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 DYRK4 3.422 5.502 5.078 3.714 1.648 1.648 −3.453 0.0313279 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 EEPD1 6.649 4.771 5.647 3.442 4.001 3.859 −3.453 0.0289321 endonuclease/exonuclease/phosphatase family domain containing 1 NAP1L1 9.078 10.402 10.009 8.157 7.820 8.614 −3.453 0.0373854 nucleosome assembly protein 1-like 1 FZD1 7.053 7.110 6.623 4.835 5.213 6.068 −3.452 0.0377348 frizzled homolog 1 (Drosophila) SCMH1 4.793 5.743 5.911 4.124 3.233 3.233 −3.451 0.0221903 sex comb on midleg homolog 1 (Drosophila) CCDC47 8.569 9.625 8.687 6.891 7.270 6.900 −3.450 0.0176419 coiled-coil domain containing 47 FLNC 6.769 7.329 8.120 4.984 5.358 6.428 −3.446 0.0356364 filamin C, gamma LEF1 6.051 5.018 4.173 3.233 3.233 3.233 −3.445 0.0309688 lymphoid enhancer-binding factor 1 EIF3D 9.453 9.804 10.229 8.203 8.173 7.669 −3.443 0.0181286 eukaryotic translation initiation factor 3, subunit D RB1 4.708 5.237 5.771 3.456 3.456 3.456 −3.438 0.0204163 retinoblastoma 1 C14orf132 5.727 5.322 5.599 3.818 3.818 3.818 −3.436 0.0131865 chromosome 14 open reading frame 132 TUBB 13.026 11.486 11.832 10.982 10.052 9.901 −3.435 0.0358187 tubulin, beta SNX17 4.672 6.489 6.360 4.710 3.648 3.648 −3.432 0.0417043 sorting nexin 17 TXNDC9 3.422 5.208 5.793 4.017 1.648 1.648 −3.423 0.0364801 thioredoxin domain containing 9 WASL 6.209 8.015 7.480 6.239 4.964 5.362 −3.423 0.0486541 Wiskott-Aldrich syndrome-like NEO1 6.221 6.694 5.201 4.091 4.447 4.604 −3.419 0.0364939 neogenin 1 ZWINT 3.422 3.294 3.544 1.648 1.648 1.648 −3.419 0.0103927 ZW10 interactor TMEM144 3.422 3.209 4.395 1.648 1.648 1.648 −3.419 0.0156225 transmembrane protein 144 PLN 3.422 4.368 3.077 1.648 1.648 1.648 −3.419 0.0179109 phospholamban TIGD3 3.422 3.832 2.943 1.648 1.648 1.648 −3.419 0.0189050 tigger transposable element derived 3 BOLA1 3.422 3.557 2.776 1.648 1.648 1.648 −3.419 0.0240783 bolA homolog 1 (E. coli)) SLCO4C1 3.422 2.776 3.557 1.648 1.648 1.648 −3.419 0.0240783 solute carrier organic anion transporter family, member 4C1 TMEM35 3.422 3.566 2.744 1.648 1.648 1.648 −3.419 0.0249931 transmembrane protein 35 ZNF137 3.422 3.645 2.710 1.648 1.648 1.648 −3.419 0.0259179 No description UQCRB 3.422 4.262 4.686 3.023 1.648 1.648 −3.419 0.0260801 ubiquinol-cytochrome c reductase binding protein UFSP2 4.422 4.405 5.529 3.718 2.648 2.648 −3.419 0.0325875 UFM1-specific peptidase 2 DTD1 3.422 4.395 5.120 3.557 1.648 1.648 −3.419 0.0382984 D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae) ACAT2 3.422 4.008 3.627 3.023 1.648 1.648 −3.419 0.0447976 acetyl-CoA acetyltransferase 2 IFNGR1 5.482 6.940 6.700 5.167 4.467 4.054 −3.417 0.0337924 interferon gamma receptor 1 ALOX15 3.422 3.420 2.304 1.648 1.648 1.648 −3.415 0.0493279 arachidonate 15-lipoxygenase SOCS1 5.982 5.420 4.826 4.182 2.648 4.210 −3.415 0.0438867 suppressor of cytokine signaling 1 FAM110B 5.775 6.329 5.913 4.762 4.141 3.818 −3.414 0.0220863 family with sequence similarity 110, member B ANP32B 8.093 8.910 8.947 7.176 6.788 6.752 −3.413 0.0221744 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B FAM160A2 4.793 6.125 5.867 4.357 3.978 4.007 −3.406 0.0471872 family with sequence similarity 160, member A2 NPDC1 8.877 7.481 8.258 6.472 6.497 6.491 −3.406 0.0285404 neural proliferation, differentiation and control, 1 CHD1L 3.947 5.626 4.738 2.970 2.970 2.970 −3.405 0.0296738 chromodomain helicase DNA binding protein 1-like DDB2 5.503 5.160 4.142 2.951 3.043 3.737 −3.401 0.0354679 damage-specific DNA binding protein 2, 48 kDa ETFA 5.503 6.710 7.203 5.167 5.017 3.737 −3.401 0.0417737 electron-transfer-flavoprotein, alpha polypeptide FAM20A 6.460 6.925 6.227 5.015 4.462 4.698 −3.399 0.0170139 family with sequence similarity 20. member A TMED10 6.038 5.556 5.219 4.385 3.456 3.456 −3.395 0.0229861 transmembrane emp24-like trafficking protein 10 (yeast) LAMP1 9.810 10.376 9.563 9.020 7.824 7.801 −3.392 0.0341279 lysosomal-associated membrane protein 1 OR51E2 7.353 8.009 7.544 6.994 5.591 5.591 −3.391 0.0464288 olfactory receptor, family 51, subfamily E, member 2 PNP 10.020 9.390 9.458 8.060 8.258 7.196 −3.391 0.0244218 purine nucleoside phosphorylase CSTB 8.305 9.421 9.749 7.731 7.661 6.983 −3.387 0.0362471 cystatin B (stefin B) TFAP4 5.503 5.496 4.817 3.737 4.151 2.233 −3.385 0.0336634 transcription factor AP-4 (activating enhancer binding protein 4) ZNF71 4.936 4.128 3.987 3.278 2.233 2.233 −3.372 0.0294139 zinc finger protein 71 C1orf123 5.838 5.632 5.542 3.881 2.970 4.453 −3.366 0.0231768 chromosome 1 open reading frame 123 UCP2 5.322 5.783 4.149 4.033 3.043 3.054 −3.365 0.0431026 uncoupling protein 2 (mitochondrial, proton carrier) BRD7 3.947 6.354 5.192 3.442 3.508 2.970 −3.364 0.0428364 bromodomain containing 7 SLC39A9 7.345 7.559 7.615 6.439 5.339 5.810 −3.361 0.0273806 solute carrier family 39 (zinc transporter), member 9 EDC3 5.204 6.090 6.344 3.456 4.694 3.865 −3.361 0.0271255 enhancer of mRNA decapping 3 homolog (S. cerevisiae) TMEM30A 8.141 9.632 9.660 7.913 7.266 6.966 −3.355 0.0379289 transmembrane protein 30A SGCB 7.281 6.968 5.971 5.517 3.970 5.536 −3.350 0.0468607 sarcoglycan, beta (43 kDa dystrophin-associated glycoprotein) GLTPD1 5.160 5.702 5.783 4.151 3.958 2.233 −3.350 0.0254887 glycolipid transfer protein domain containing 1 TMCO1 5.877 7.619 6.747 5.193 5.005 4.173 −3.344 0.0287567 transmembrane and coiled-coil domains 1 PCOLCE2 4.264 7.566 5.044 2.648 4.273 3.303 −3.342 0.0474846 procollagen C-endopeptidase enhancer 2 WDR83 4.264 4.388 5.542 2.648 2.648 2.648 −3.340 0.0158562 WD repeat domain 83 CCNT1 4.709 5.645 4.473 2.970 3.508 2.970 −3.337 0.0250111 cyclin T1 ZNF117 4.709 5.019 4.901 3.988 2.970 2.970 −3.337 0.0333868 zinc finger protein 117 C20orf30 9.320 8.709 8.701 7.990 6.971 6.522 −3.336 0.0319435 chromosome 20 open reading frame 30 PRNP 9.295 10.501 9.601 7.557 8.234 8.535 −3.334 0.0344073 prion protein ZNF92 3.619 3.968 4.887 2.233 2.233 2.233 −3.329 0.0190679 zinc finger protein 92 NDUFB11 7.390 7.390 7.244 6.032 5.513 5.509 −3.329 0.0181924 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3 kDa RPL29 6.061 5.673 6.491 2.625 4.757 4.692 −3.328 0.0329425 ribosomal protein L29 ZC3H4 6.730 7.161 7.582 5.153 5.429 5.564 −3.322 0.0189231 zinc finger CCCH-type containing 4 EPB41L2 6.497 7.843 7.245 5.647 4.641 6.111 −3.322 0.0412634 erythrocyte membrane protein band 4.1-like 2 SMG7 6.147 6.259 6.109 5.128 4.377 4.382 −3.322 0.0275158 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) DCAF11 6.472 6.159 6.218 5.526 4.488 4.264 −3.318 0.0408697 DDB1 and CUL4 associated factor 11 ZBTB2 6.818 7.188 6.401 5.088 4.504 5.458 −3.317 0.0233792 zinc finger and BTB domain containing 2 RPS15A 9.776 10.479 10.602 7.931 8.749 9.132 −3.317 0.0328357 ribosomal protein S15a TPCN1 6.099 6.709 7.175 4.741 4.775 5.446 −3.316 0.0297099 two pore segment channel 1 BACH1 6.503 7.853 7.846 5.477 5.506 6.124 −3.314 0.0361903 BTB and CNC homology 1, basic leucine zipper transcription factor 1 RCOR3 6.137 5.950 5.536 3.808 4.115 4.409 −3.312 0.0180544 REST corepressor 3 ZNF805 5.461 6.980 6.485 4.833 4.758 4.761 −3.305 0.0453785 zinc finger protein 805 NCAM1 6.471 4.448 4.957 3.637 3.233 3.233 −3.303 0.0319837 neural cell adhesion molecule 1 PHF13 7.172 6.946 6.536 4.814 5.009 6.122 −3.300 0.0415795 PHD finger protein 13 BMP4 7.837 7.259 6.105 4.385 4.385 6.140 −3.294 0.0328447 bone morphogenetic protein 4 SIKE1 4.580 5.646 5.716 3.997 3.859 3.456 −3.292 0.0393875 suppressor of IKBKE 1 CHRNB1 5.377 5.370 5.555 3.838 2.648 3.694 −3.289 0.0158652 cholinergic receptor, nicotinic, beta 1 (muscle) EI24 8.132 9.110 8.471 7.474 6.754 6.044 −3.288 0.0300676 etoposide induced 2.4 mRNA LEPR 8.861 9.485 9.064 7.348 7.175 7.699 −3.287 0.0187567 leptin receptor C2orf29 4.524 5.867 5.959 4.242 3.508 3.859 −3.287 0.0464766 chromosome 2 open reading frame 29 EFR3A 5.620 6.277 6.300 4.562 4.600 3.648 −3.283 0.0241577 EFR3 homolog A (S. cerevisiae) PSMB1 7.212 10.590 7.496 6.310 5.782 5.598 −3.283 0.0314118 proteasome (prosome, macropain) subunit, beta type, 1 MACROD1 4.142 5.143 4.142 3.429 3.043 2.233 −3.282 0.0448558 MACRO domain containing 1 NUDT16L1 4.008 4.376 4.339 2.625 1.648 2.752 −3.280 0.0194201 nudix (nucleoside diphosphate linked moiety X)-type motif 16- like 1 B3GNT2 6.536 7.571 6.203 5.570 4.490 5.226 −3.279 0.0399400 UDP-GlcNAc:betaGal beta-1,3-N- acetylglucosaminyltransferase 2 SLC36A4 4.872 5.297 5.572 3.456 3.859 3.456 −3.279 0.0219075 solute carrier family 36 (proton/amino acid symporter), member 4 SET 10.094 10.702 10.630 8.721 8.970 8.917 −3.278 0.0218555 SET nuclear oncogene C16orf72 9.360 9.327 9.067 6.778 7.615 8.438 −3.276 0.0396177 chromosome 16 open reading frame 72 TSC22D1 9.761 10.710 10.438 8.154 8.250 8.999 −3.274 0.0230159 TSC22 domain family, member 1 RALA 7.670 8.422 8.509 6.620 6.798 6.562 −3.273 0.0292676 v-ral simian leukemia viral oncogene homolog A (ras related) C19orf43 10.432 10.367 10.606 8.349 8.726 8.957 −3.263 0.0147678 chromosome 19 open reading frame 43 SLC5A3 6.247 7.236 7.059 4.642 4.823 5.532 −3.258 0.0235567 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 BBS10 5.008 5.309 5.601 3.897 3.659 3.303 −3.257 0.0206492 Bardet-Biedl syndrome 10 CIR1 5.350 5.567 5.954 3.997 3.859 3.865 −3.253 0.0162977 corepressor interacting with RBPJ, 1 SMAD4 6.620 7.253 7.269 6.027 5.325 4.919 −3.252 0.0325542 SMAD family member 4 TAF7 5.847 6.551 6.081 4.850 4.453 2.233 −3.251 0.0272503 TAF7 RNA polymerase II, TATA box binding protein (TBP)- associated factor, 55 kDa EIF4H 11.021 12.110 11.626 9.927 9.993 9.704 −3.248 0.0243733 eukaryotic translation initiation factor 4H NAPA 9.892 9.000 9.296 7.989 7.597 7.445 −3.246 0.0231678 N-ethylmaleimide-sensitive factor attachment protein, alpha PARVA 7.602 6.960 7.478 5.780 5.481 5.789 −3.244 0.0202049 parvin, alpha RAB2A 6.667 6.660 6.007 5.290 4.963 3.897 −3.242 0.0327310 RAB2A, member RAS oncogene family PDGFB 5.702 4.666 4.610 3.442 2.970 2.970 −3.239 0.0218125 platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) SH3GL1 8.501 8.897 9.173 7.599 7.202 6.256 −3.238 0.0254797 SH3-domain GRB2-like 1 ABCB7 3.792 4.356 4.989 2.648 3.294 2.648 −3.236 0.0423144 ATP-binding cassette, sub-family B (MDR/TAP), member 7 C17orf81 5.346 6.204 6.146 4.355 4.514 4.173 −3.227 0.0298867 chromosome 17 open reading frame 81 TOB1 8.723 10.122 8.987 7.296 7.249 7.752 −3.227 0.0258908 transducer of ERBB2, 1 TPMS 9.878 10.051 9.684 8.270 8.031 8.189 −3.226 0.0141605 tropomyosin 3 ITGB1 12.123 12.748 11.397 10.433 10.621 9.720 −3.225 0.0276974 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) ZZZ3 5.173 5.785 6.171 4.388 4.097 3.897 −3.223 0.0303054 zinc finger, ZZ-type containing 3 LOXL1 9.666 8.067 7.339 6.379 6.011 6.402 −3.223 0.0287899 lysyl oxidase-like 1 FNTA 8.135 8.207 8.816 7.016 7.010 6.447 −3.222 0.0288919 farnesyltransferase, CAAX box, alpha POMP 9.346 9.985 10.316 8.765 8.297 7.187 −3.222 0.0339546 proteasome maturation protein NUP93 6.470 6.806 6.320 5.854 4.784 3.897 −3.219 0.0444974 nucleoporin 93 kDa LPXN 6.190 6.554 6.267 4.124 4.581 5.005 −3.219 0.0193744 leupaxin MYH10 6.046 5.084 5.701 3.881 4.361 3.516 −3.215 0.0278922 myosin. heavy chain 10. non-muscle IMMP1L 4.423 4.564 4.684 3.023 2.739 2.752 −3.213 0.0136045 IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) CDK9 8.990 9.257 9.228 7.498 7.545 7.566 −3.211 0.0148308 cyclin-dependent kinase 9 PXMP2 3.194 1.962 2.329 0.648 0.648 0.648 −3.207 0.0211740 peroxisomal membrane protein 2, 22 kDa SSR4 8.714 9.655 8.896 8.084 7.215 6.838 −3.205 0.0335317 signal sequence receptor, delta (translocon-associated protein delta) SMARCD2 6.887 6.646 7.273 5.593 4.361 5.424 −3.205 0.0256510 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 COQ5 3.860 3.881 3.888 2.202 3.284 0.648 −3.204 0.0486832 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) FAM165B 6.667 7.960 7.229 5.551 5.265 5.907 −3.200 0.0298229 family with sequence similarity 165, member B CTSO 9.117 6.762 6.748 5.072 5.733 5.558 −3.196 0.0356925 cathepsin O C18orf10 5.482 5.816 6.202 4.526 4.043 4.007 −3.196 0.0240101 chromosome 18 open reading frame 10 EMP1 11.445 12.546 12.363 9.769 10.666 10.881 −3.194 0.0362977 epithelial membrane protein 1 TNFRSF10B 7.864 9.846 8.110 6.434 6.392 6.807 −3.194 0.0268295 tumor necrosis factor receptor superfamily, member 10b ACAA2 6.983 6.657 5.778 4.830 5.405 4.104 −3.190 0.0386347 acetyl-CoA acyltransferase 2 ZHX2 6.626 7.116 6.682 5.443 5.288 4.693 −3.188 0.0235269 zinc fingers and homeoboxes 2 SPRED2 6.311 7.149 6.734 5.078 4.784 5.062 −3.186 0.0188870 sprouty-related, EVH1 domain containing 2 KIAA0391 6.038 5.203 5.439 4.350 4.368 2.648 −3.181 0.0414180 KIAA0391 LPL 7.610 6.617 7.221 6.194 4.447 5.553 −3.179 0.0398638 lipoprotein lipase F5 7.791 8.585 8.247 6.364 6.582 6.626 −3.171 0.0207872 coagulation factor V (proaccelerin, labile factor) XPOT 7.212 7.854 7.363 6.668 5.698 4.553 −3.171 0.0383144 exportin, tRNA (nuclear export receptor for tRNAs) INPP5E 4.709 5.551 5.107 3.442 3.899 2.970 −3.171 0.0274575 inositol polyphosphate-5-phosphatase, 72 kDa RDH14 6.291 6.228 6.321 4.667 4.628 3.897 −3.168 0.0148995 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) SGMS2 7.665 8.747 7.416 5.752 6.376 6.160 −3.167 0.0253889 sphingomyelin synthase 2 MATR3 8.082 9.124 8.810 7.147 6.820 7.458 −3.167 0.0365771 matrin 3 CADM3 5.877 4.590 4.895 3.848 3.233 3.233 −3.163 0.0329244 cell adhesion molecule 3 APP 11.417 11.575 11.666 9.756 10.260 9.875 −3.162 0.0201390 amyloid beta (A4) precursor protein RNF152 5.661 6.192 6.655 4.907 4.001 4.670 −3.161 0.0319588 ring finger protein 152 MRPL49 8.413 8.091 8.338 7.420 6.681 6.120 −3.155 0.0384211 mitochondrial ribosomal protein L49 ERMAP 4.895 4.281 4.951 2.648 3.294 2.648 −3.153 0.0180974 erythroblast membrane-associated protein (Scianna blood group) LMNA 12.627 12.228 12.564 10.750 10.574 11.748 −3.146 0.0459088 lamin A/C C10orf78 5.160 4.481 3.871 2.233 2.233 3.508 −3.143 0.0323622 chromosome 10 open reading frame 78 FBXO34 5.552 4.946 5.646 4.388 3.294 3.897 −3.142 0.0396087 F-box protein 34 IER2 12.274 12.279 12.538 10.445 10.984 10.629 −3.140 0.0174936 immediate early response 2 MYL12A 10.475 10.618 10.820 8.969 9.459 7.829 −3.137 0.0262111 myosin, light chain 12A, regulatory, non-sarcomeric TNFSF12 4.860 4.154 3.296 1.648 1.648 3.294 −3.134 0.0391019 tumor necrosis factor (ligand) superfamily, member 12 CHCHD5 5.452 5.042 5.942 4.017 3.805 3.557 −3.133 0.0236558 coiled-coil-helix-coiled-coil-helix domain containing 5 FLRT2 7.445 6.749 6.407 4.767 5.540 5.195 −3.117 0.0278250 fibronectin leucine rich transmembrane protein 2 GTF2A1 6.202 4.990 4.529 4.262 2.987 3.351 −3.116 0.0465612 general transcription factor IIA, 1, 19/37 kDa SLC39A14 9.051 10.866 9.789 8.351 8.150 8.070 −3.114 0.0382250 solute carrier family 39 (zinc transporter), member 14 BCL6B 4.142 3.799 3.870 2.233 2.233 2.233 −3.110 0.0132898 B-cell CLL/lymphoma 6, member B APPL1 7.055 7.668 6.802 5.418 5.649 5.203 −3.108 0.0206062 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 FAM101B 6.777 7.580 6.244 5.596 5.202 4.608 −3.108 0.0332475 family with sequence similarity 101, member B HERC3 4.948 6.110 5.643 3.961 4.007 4.264 −3.107 0.0389986 hect domain and RLD 3 LRIG1 5.076 6.146 5.945 3.442 3.508 5.030 −3.104 0.0437792 leucine-rich repeats and immunoglobulin-like domains 1 RASA1 6.280 5.675 6.399 4.782 4.385 4.042 −3.102 0.0234901 RAS p21 protein activator (GTPase activating protein) 1 ASNS 5.322 6.225 5.720 4.508 4.592 3.054 −3.101 0.0414090 asparagine synthetase (glutamine-hydrolyzing) SCAMP1 6.815 6.484 6.089 4.456 4.456 5.293 −3.101 0.0248953 secretory carrier membrane protein 1 CSNK1G2 7.066 6.868 7.634 5.238 5.531 5.668 −3.094 0.0208142 casein kinase 1, gamma 2 C2orf79 4.817 5.989 5.850 3.278 3.467 4.360 −3.091 0.0280891 chromosome 2 open reading frame 79 TBC1D9 8.042 7.610 7.365 6.381 5.834 5.984 −3.086 0.0247802 TBC1 domain family, member 9 (with GRAM domain) DRI 7.261 7.805 7.056 5.736 5.432 5.962 −3.082 0.0233882 down-regulator of transcription 1, TBP-binding (negative cofactor 2) TMEM167A 7.179 7.801 7.562 6.334 5.738 5.555 −3.081 0.0255754 transmembrane protein 167A RC3H1 7.091 8.438 8.423 6.110 6.400 6.815 −3.080 0.0480530 ring finger and CCCH-type domains 1 RGS4 6.492 5.687 4.856 3.637 3.233 4.914 −3.080 0.0489591 regulator of G-protein signaling 4 UGP2 6.833 8.557 7.031 5.861 5.508 5.210 −3.080 0.0283068 UDP-glucose pyrophosphorylase 2 C2orf18 6.537 8.117 7.603 6.495 5.569 5.039 −3.076 0.0459802 chromosome 2 open reading frame 18 CXorf38 3.860 2.202 2.268 0.648 0.648 0.648 −3.073 0.0201958 chromosome X open reading frame 38 CHGA 3.860 1.649 2.268 0.648 0.648 0.648 −3.073 0.0333958 chromogranin A (parathyroid secretory protein 1) SUSD2 8.210 4.589 4.933 2.970 4.001 3.516 −3.071 0.0418589 sushi domain containing 2 PAN3 7.622 8.483 8.523 6.458 6.904 6.111 −3.071 0.0265737 PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) ADAMTS1 8.005 9.147 8.605 7.378 6.387 7.226 −3.070 0.0404752 ADAM metallopeptidase with thrombospondin type 1 motif, 1 LY6E 10.488 9.391 9.464 8.136 8.870 7.761 −3.070 0.0486395 lymphocyte antigen 6 complex, locus E FAM108B1 7.392 8.205 8.637 6.471 6.427 7.019 −3.070 0.0496489 family with sequence similarity 108, member B1 SDHAF2 6.887 7.780 7.879 6.374 5.752 5.270 −3.068 0.0315560 succinate dehydrogenase complex assembly factor 2 KIAA0146 4.264 4.622 4.969 3.897 2.648 2.648 −3.066 0.0444163 KIAA0146 NITI 4.264 3.402 4.492 2.648 2.648 2.648 −3.066 0.0447172 nitrilase 1 URM1 4.264 6.004 6.073 4.927 2.648 2.648 −3.066 0.0491310 ubiquitin related modifier 1 TMEM223 4.264 5.845 4.948 4.388 2.648 2.648 −3.066 0.0496399 transmembrane protein 223 TSSC4 6.135 7.349 6.791 4.754 5.423 5.176 −3.063 0.0325362 tumor suppressing subtransferable candidate 4 FCGRT 9.312 9.051 8.702 7.628 7.088 7.449 −3.061 0.0226804 Fc fragment of IgG, receptor, transporter, alpha HCFC1 8.453 8.750 8.777 7.140 6.987 7.153 −3.052 0.0180149 host cell factor C1 (VP16-accessory protein) MYL6 11.167 11.975 11.449 10.140 10.364 9.558 −3.052 0.0361584 myosin, light chain 6, alkali, smooth muscle and non-muscle SHOC2 7.337 7.732 7.442 5.822 6.122 5.821 −3.052 0.0195913 soc-2 suppressor of clear homolog (C. elegans) CCDC101 6.829 5.811 6.388 4.721 4.529 5.220 −3.050 0.0374582 coiled-coil domain containing 101 CCNG2 8.081 7.451 7.259 5.842 5.376 6.736 −3.050 0.0402742 cyclin G2 ACTR10 4.142 4.599 5.144 3.535 3.043 2.233 −3.049 0.0354014 actin-related protein 10 homolog (S. cerevisiae) RGL1 6.309 5.955 5.642 4.556 4.701 4.007 −3.048 0.0296253 ral guanine nucleotide dissociation stimulator-like 1 ATAD1 7.141 6.850 6.791 6.258 5.243 4.990 −3.046 0.0495421 ATPase family, AAA domain containing 1 TBC1D2B 8.178 7.976 8.029 6.423 5.952 6.622 −3.043 0.0171823 TBC1 domain family, member 2B RAB11 B 8.331 7.197 7.546 6.726 6.034 4.590 −3.042 0.0391927 RAB11B, member RAS oncogene family ABTB1 5.293 5.305 5.683 4.490 3.233 3.701 −3.040 0.0329563 ankyrin repeat and BTB (POZ) domain containing 1 GPSM3 7.114 5.875 4.854 4.273 3.294 4.346 −3.036 0.0366610 G-protein signaling modulator 3 AFAP1 6.942 7.034 6.749 5.340 5.189 5.420 −3.036 0.0165737 actin filament associated protein 1 FAM102A 10.025 9.531 9.614 7.913 8.017 8.466 −3.025 0.0239206 family with sequence similarity 102, member A PEAR1 7.521 6.372 6.880 5.621 3.970 5.925 −3.023 0.0487664 platelet endothelial aggregation receptor 1 CD59 10.620 11.427 12.120 9.832 9.867 9.810 −3.022 0.0417418 CD59 molecule, complement regulatory protein RPL14 10.710 11.421 11.256 9.370 9.661 9.705 −3.021 0.0260891 ribosomal protein L14 RPL30 13.209 13.555 13.241 11.614 11.674 11.945 −3.020 0.0189931 ribosomal protein L30 CES2 6.814 5.970 6.298 5.614 4.628 4.377 −3.016 0.0490693 carboxylesterase 2 EXOC3 5.888 6.892 7.094 5.526 5.302 3.865 −3.011 0.0461633 exocyst complex component 3 ELF2 6.277 6.321 6.156 4.649 4.566 4.838 −3.009 0.0167678 E74-like factor 2 (ets domain transcription factor) ESD 3.792 5.479 4.805 3.218 2.648 3.303 −3.005 0.0439179 esterase D SFRS12IP1 7.522 8.344 7.484 6.644 6.387 5.897 −3.004 0.0407844 No description LDLRAD3 7.054 8.598 6.343 5.469 5.515 4.827 −3.001 0.0302666 low density lipoprotein receptor class A domain containing 3 NGFRAP1 4.142 3.817 4.290 2.233 3.043 2.233 −2.997 0.0291185 nerve growth factor receptor (TNFRSF16) associated protein 1 AP1S2 5.229 6.390 6.392 4.809 3.694 4.007 −2.997 0.0295359 adaptor-related protein complex 1, sigma 2 subunit MGAT3 6.777 4.499 3.815 3.429 2.233 3.054 −2.994 0.0434610 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N- acetylglucosaminyltransferase FAM198B 8.082 8.737 7.636 6.143 6.506 6.692 −2.982 0.0262728 family with sequence similarity 198, member B NEK6 4.086 4.807 4.922 3.233 3.233 3.233 −2.977 0.0402894 NIMA (never in mitosis gene a)-related kinase 6 C1orf86 6.756 6.965 7.803 5.409 5.304 5.398 −2.962 0.0204073 chromosome 1 open reading frame 86 CNN3 12.047 11.043 11.258 9.693 9.656 10.055 −2.960 0.0271948 calponin 3, acidic MEIS2 6.551 7.510 7.318 5.637 5.614 5.948 −2.952 0.0434977 Meis homeobox 2 STUB1 6.036 7.397 6.643 5.196 4.811 5.082 −2.951 0.0319206 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase PHF11 5.076 6.251 5.913 4.546 4.385 3.516 −2.949 0.0417827 PHD finger protein 11 SEC62 8.212 9.464 8.705 7.572 7.146 6.679 −2.946 0.0348884 SEC62 homolog (S. cerevisiae) FAM109B 6.713 6.039 5.595 4.713 4.294 4.481 −2.945 0.0298478 family with sequence similarity 109, member B CDK2 6.507 7.377 7.801 5.837 5.475 5.821 −2.939 0.0413203 cyclin-dependent kinase 2 FAM46B 7.114 7.233 8.436 5.558 6.424 5.682 −2.939 0.0361154 family with sequence similarity 46. member B FSTL1 13.885 12.483 12.426 11.163 10.872 11.667 −2.936 0.0390783 follistatin-like 1 PPP2R4 6.401 6.807 5.760 5.255 5.089 3.233 −2.932 0.0474076 protein phosphatase 2A activator, regulatory subunit 4 SLC25A6 12.075 11.862 12.392 10.233 10.842 10.576 −2.928 0.0254201 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 NDUFAF3 6.710 6.867 6.326 5.797 5.162 3.859 −2.924 0.0446416 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3 RHBDF1 6.665 6.846 7.502 5.822 5.517 5.118 −2.924 0.0346950 rhomboid 5 homolog 1 (Drosophila) C11orf51 4.142 5.013 4.417 2.233 3.467 3.054 −2.918 0.0383636 chromosome 11 open reading frame 51 OR1J1 4.314 5.808 5.256 3.081 2.987 4.262 −2.918 0.0460496 olfactory receptor, family 1, subfamily J, member 1 HTRA2 6.062 6.950 6.475 5.153 4.646 4.933 −2.912 0.0282180 HtrA serine peptidase 2 TNXB 7.168 6.242 6.941 5.400 5.292 5.536 −2.911 0.0427484 tenascin XB C10orf46 6.893 7.404 7.206 5.842 5.863 5.160 −2.911 0.0288392 chromosome 10 open reading frame 46 POLR1E 6.852 7.606 6.156 5.311 5.531 4.946 −2.910 0.0389334 polymerase (RNA) I polypeptide E, 53 kDa CSNK1A1 9.453 9.394 9.430 7.890 8.367 7.786 −2.909 0.0295899 casein kinase 1, alpha 1 ZFP91 9.701 9.897 9.823 8.452 7.398 8.282 −2.908 0.0227948 zinc finger protein 91 homolog (mouse) TBC1D10B 6.814 7.569 7.160 5.913 5.276 5.718 −2.904 0.0298319 TBC1 domain family, member 10B FLRT3 4.264 3.675 4.186 2.648 2.648 2.648 −2.904 0.0312246 fibronectin leucine rich transmembrane protein 3 PPP2R1A 10.151 9.564 9.607 8.613 8.584 7.581 −2.904 0.0405979 protein phosphatase 2, regulatory subunit A, alpha SLC16A2 4.709 4.508 4.754 2.970 3.827 2.970 −2.903 0.0411276 solute carrier family 16, member 2 (monocarboxylic acid transporter 8) NEK3 4.423 2.455 3.186 1.648 1.648 1.648 −2.903 0.0422236 NIMA (never in mitosis gene a)-related kinase 3 ZBTB8A 9.600 10.194 10.311 8.523 8.391 8.775 −2.900 0.0311990 zinc finger and BTB domain containing 8A RNF14 6.291 5.178 5.914 4.700 4.378 3.694 −2.899 0.0436440 ring finger protein 14 HP1BP3 9.358 9.399 9.491 7.864 7.747 8.221 −2.898 0.0241910 heterochromatin protein 1, binding protein 3 TMED4 6.262 6.336 5.545 4.804 4.254 4.071 −2.892 0.0264253 transmembrane emp24 protein transport domain containing 4 ARF4 10.242 11.025 10.251 8.711 8.771 8.868 −2.890 0.0203470 ADP-ribosylation factor 4 OSBPL5 7.680 8.327 7.468 6.929 6.150 5.902 −2.888 0.0433161 oxysterol binding protein-like 5 FOXJ3 6.749 7.606 7.058 6.153 5.528 5.027 −2.887 0.0381660 forkhead box J3 CAP1 9.823 10.131 9.506 8.601 8.497 7.320 −2.886 0.0337771 CAP, adenylate cyclase-associated protein 1 (yeast) TRIM47 6.204 7.676 7.675 6.146 5.078 5.334 −2.886 0.0463511 tripartite motif-containing 47 AADAT 3.619 5.032 5.199 3.670 2.233 2.233 −2.885 0.0378402 aminoadipate aminotransferase DDX50 3.947 5.211 4.498 2.970 2.970 2.970 −2.884 0.0336426 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 ABCC9 5.937 7.035 6.336 4.824 4.812 4.580 −2.878 0.0250617 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 NOB1 5.952 6.657 6.083 4.892 5.133 4.404 −2.875 0.0403317 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) NDRG4 4.378 4.842 4.491 2.970 2.970 2.970 −2.870 0.0180634 NDRG family member 4 ISPD 3.194 1.962 2.170 0.648 0.648 0.648 −2.870 0.0241196 isoprenoid synthase domain containing ZNF165 3.619 3.754 4.933 2.233 2.233 2.233 −2.869 0.0233286 zinc finger protein 165 MTUS1 7.861 7.887 8.866 5.518 6.421 7.346 −2.869 0.0410492 microtubule associated tumor suppressor 1 TIFA 4.214 5.606 4.974 3.456 3.456 3.456 −2.866 0.0452544 TRAF-interacting protein with forkhead-associated domain MMD 4.378 5.669 5.576 4.151 2.970 2.970 −2.865 0.0331130 monocyte to macrophage differentiation-associated LOC100190939 7.394 7.424 7.731 5.908 6.308 5.802 −2.860 0.0248503 No description SUMO3 8.849 8.541 8.288 7.711 7.027 6.318 −2.857 0.0426617 SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae) PLEKHG3 5.973 6.194 5.931 4.463 4.951 4.409 −2.848 0.0296828 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 MPRIP 8.719 8.954 8.868 7.210 7.824 7.356 −2.846 0.0330381 myosin phosphatase Rho interacting protein SYNGR2 8.641 8.625 8.007 7.403 7.117 5.608 −2.845 0.0432218 synaptogyrin 2 ZNF706 7.651 8.382 8.395 6.543 6.623 6.888 −2.842 0.0338312 zinc finger protein 706 TXNDC5 7.292 9.196 7.060 5.774 6.040 5.786 −2.841 0.0327948 thioredoxin domain containing 5 (endoplasmic reticulum) SGPP1 4.482 6.569 4.739 3.233 3.233 3.701 −2.839 0.0385168 sphingosine-1-phosphate phosphatase 1 TNFRSF14 7.450 6.204 6.532 5.176 4.699 5.103 −2.837 0.0274915 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) DEPDC6 3.619 3.737 4.624 2.233 2.233 2.233 −2.836 0.0219234 No description PELI1 10.037 9.775 9.909 7.919 8.407 8.860 −2.833 0.0313459 pellino homolog 1 (Drosophila) NUMBL 6.599 6.676 6.854 5.279 5.098 5.337 −2.830 0.0212891 numb homolog (Drosophila)-like IKBIP 5.659 5.451 5.316 4.591 3.818 3.818 −2.824 0.0392017 IKBKB interacting protein KDR 5.639 5.654 4.861 4.159 3.456 3.865 −2.818 0.0323373 kinase insert domain receptor (a type III receptor tyrosine kinase) PPIC 10.003 7.443 6.891 6.232 6.086 5.398 −2.815 0.0407199 peptidylprolyl isomerase C (cyclophilin C) C8orf84 5.107 5.224 4.946 3.456 4.174 3.456 −2.809 0.0371317 chromosome 8 open reading frame 84 ASS1 7.319 7.355 8.170 6.147 6.680 4.042 −2.808 0.0441189 argininosuccinate synthase 1 ADK 6.135 6.625 6.831 5.137 5.466 3.859 −2.805 0.0382069 adenosine kinase YES1 8.236 8.071 8.170 6.655 6.892 6.585 −2.801 0.0225924 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 PTPRG 6.835 7.116 7.204 6.020 5.506 5.352 −2.794 0.0329064 protein tyrosine phosphatase, receptor type, G GNAQ 4.525 4.501 4.861 2.951 3.043 3.508 −2.793 0.0287990 guanine nucleotide binding protein (G protein), q polypeptide PEX19 5.789 6.084 5.488 5.022 4.007 4.013 −2.790 0.0460821 peroxisomal biogenesis factor 19 GSDMD 6.753 6.638 6.332 5.157 5.291 4.536 −2.790 0.0263352 gasdermin D WEE1 8.951 9.542 9.679 7.705 8.199 7.733 −2.790 0.0308579 WEE1 homolog (S. pombe) LOC100233209 7.610 8.654 8.402 6.939 6.409 6.922 −2.789 0.0420114 No description SAMD4B 7.465 7.827 7.444 6.396 5.986 5.790 −2.788 0.0261161 sterile alpha motif domain containing 4B RWDD1 8.608 8.943 8.220 7.070 7.505 6.743 −2.783 0.0352891 RWD domain containing 1 MOBKL1B 5.204 5.865 5.328 3.871 3.633 4.389 −2.781 0.0337369 MOB1, Mps One Binder kinase activator-like 1 B (yeast) ARAP1 5.614 6.605 6.086 4.610 4.240 4.631 −2.780 0.0282333 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ARL6IP4 7.609 8.701 8.556 7.226 6.156 6.171 −2.780 0.0315879 ADP-ribosylation-like factor 6 interacting protein 4 COL21A1 4.482 4.707 4.893 3.233 3.233 3.233 −2.777 0.0229369 collagen, type XXI, alpha 1 CCNY 8.699 8.816 7.758 7.343 6.824 6.623 −2.776 0.0431317 cyclin Y EGR1 14.080 13.203 13.535 12.050 11.731 12.639 −2.773 0.0428225 early growth response 1 BLOC1S3 6.667 6.908 6.911 5.795 5.437 4.952 −2.773 0.0348385 biogenesis of lysosomal organelles complex-1, subunit 3 WIPF2 8.144 8.171 8.100 7.291 6.674 6.553 −2.769 0.0436794 WAS/WASL interacting protein family, member 2 C19orf42 6.275 6.259 6.378 5.024 4.812 3.752 −2.757 0.0254381 chromosome 19 open reading frame 42 IRF2 6.782 5.889 6.826 5.108 5.508 4.432 −2.745 0.0482686 interferon regulatory factor 2 CHSY3 5.688 4.103 3.807 3.218 2.648 2.648 −2.741 0.0464676 chondroitin sulfate synthase 3 C14orf126 3.619 3.687 4.160 2.233 2.233 2.233 −2.740 0.0202652 chromosome 14 open reading frame 126 HSD17B12 4.969 5.932 6.099 4.884 3.827 3.516 −2.738 0.0488288 hydroxysteroid (17-beta) dehydrogenase 12 ELOVL7 5.293 5.296 4.567 3.848 3.233 3.233 −2.728 0.0282028 ELOVL family member 7, elongation of long chain fatty acids (yeast) C20orf199 9.828 9.891 10.549 8.382 8.667 8.791 −2.725 0.0319678 No description METAP1 5.899 6.934 6.305 5.137 4.933 4.453 −2.725 0.0362790 methionyl aminopeptidase 1 HIATL1 7.326 8.636 8.007 6.586 6.166 6.562 −2.723 0.0387955 hippocampus abundant transcript-like 1 MTA1 7.732 7.945 7.035 6.288 6.323 5.809 −2.721 0.0410354 metastasis associated 1 GUCY1A3 6.546 6.182 5.642 4.976 4.741 4.584 −2.716 0.0442867 guanylate cyclase 1, soluble, alpha 3 MAP3K7 5.204 5.436 5.166 3.997 3.859 3.456 −2.711 0.0250776 mitogen-activated protein kinase kinase kinase 7 JPH4 4.969 4.407 4.107 2.970 2.970 2.970 −2.707 0.0285175 junctophilin 4 ARMC10 3.619 3.670 4.918 2.233 3.043 2.233 −2.706 0.0472461 armadillo repeat containing 10 ZNF264 7.562 8.437 7.905 6.226 6.469 6.816 −2.705 0.0367983 zinc finger protein 264 YWHAG 10.827 11.779 11.556 9.486 10.049 10.344 −2.704 0.0477466 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide RILP 5.264 4.721 4.447 3.830 1.648 3.557 −2.702 0.0480620 Rab interacting lysosomal protein PSMA3 3.619 5.222 5.311 3.877 2.233 2.233 −2.701 0.0422090 proteasome (prosome, macropain) subunit, alpha type, 3 DIABLO 6.875 7.790 7.244 6.371 5.564 5.442 −2.701 0.0414451 diablo homolog (Drosophila) PLIN3 8.751 9.479 9.366 7.937 7.372 8.020 −2.693 0.0401653 perilipin 3 NRSN2 4.619 5.600 4.868 4.173 3.233 3.233 −2.689 0.0475144 neurensin 2 JOSD1 8.294 9.063 8.950 7.007 7.183 7.636 −2.689 0.0346464 Josephin domain containing 1 SUPT7L 6.028 6.457 6.328 5.035 4.515 4.934 −2.680 0.0295990 suppressor of Ty 7 (S. cerevisiae)-like GTF3C1 7.699 7.649 8.127 6.598 6.705 6.061 −2.679 0.0391601 general transcription factor IHC, polypeptide 1, alpha 220 kDa CTBP1 9.176 9.527 8.892 8.107 7.946 7.386 −2.675 0.0414984 C-terminal binding protein 1 PIGN 4.839 5.645 5.624 4.225 3.970 3.970 −2.674 0.0478568 phosphatidylinositol glycan anchor biosynthesis, class N POLR2G 7.394 6.882 7.007 6.259 5.591 5.082 −2.668 0.0447678 polymerase (RNA) II (DNA directed) polypeptide G B4GALT1 10.277 10.815 10.355 8.862 9.119 9.361 −2.665 0.0363636 UDP-Gal:betaGlcNAc beta 1.4-galactosyltransferase, polypeptide 1 GIPC1 7.227 7.147 7.677 5.812 6.490 4.646 −2.665 0.0416336 GIPC PDZ domain containing family, member 1 USP6NL 4.378 5.265 4.180 2.970 2.970 2.970 −2.652 0.0280600 USP6 N-terminal like MEX3B 4.378 5.538 4.350 2.970 3.508 2.970 −2.652 0.0372960 mex-3 homolog B (C. elegans) SECTM1 4.378 4.957 5.235 4.042 2.970 2.970 −2.652 0.0439588 secreted and transmembrane 1 EHBP1 5.378 6.149 5.826 4.225 3.970 4.803 −2.652 0.0404932 EH domain binding protein 1 SPCS1 9.466 8.905 8.849 8.094 7.499 6.134 −2.651 0.0366097 signal peptidase complex subunit 1 homolog (S. cerevisiae) FOSL2 10.562 9.175 9.312 8.031 7.770 8.574 −2.648 0.0476482 FOS-like antigen 2 CALCRL 5.745 5.692 5.744 4.835 4.339 4.173 −2.647 0.0425196 calcitonin receptor-like CUL7 6.735 5.807 6.447 5.512 4.405 4.681 −2.643 0.0493764 cullin 7 NDUFS3 6.165 6.232 6.344 5.102 4.346 4.830 −2.643 0.0287206 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30 kDa (NADH-coenzyme Q reductase) TMEM167B 6.259 6.919 6.923 5.683 5.034 4.861 −2.636 0.0360489 transmembrane protein 167B PPP1R15B 11.352 11.212 10.872 9.510 9.476 10.362 −2.633 0.0478374 protein phosphatase 1, regulatory (inhibitor) subunit 15B CTBS 6.027 5.968 6.558 4.981 4.572 4.650 −2.632 0.0307844 chitobiase, di-N-acetyl- GUK1 8.421 9.073 8.667 7.272 7.226 7.489 −2.631 0.0332877 guanylate kinase 1 MAD1L1 6.038 5.512 6.395 4.117 5.023 4.294 −2.629 0.0405120 MAD1 mitotic arrest deficient-like 1 (yeast) VAT1 10.213 9.085 10.164 8.819 7.869 8.275 −2.628 0.0488939 vesicle amine transport protein 1 homolog (T. californica) ARPC4 10.175 9.533 9.251 8.885 8.139 6.730 −2.627 0.0497591 actin related protein 2/3 complex, subunit 4. 20 kDa AKR7A2 3.792 5.426 4.040 2.648 2.648 2.648 −2.623 0.0326776 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) ZNF148 5.872 6.440 5.894 4.845 4.845 4.482 −2.620 0.0383941 zinc finger protein 148 MRPL40 3.619 4.481 3.467 2.233 2.233 2.233 −2.612 0.0276066 mitochondrial ribosomal protein L40 ZNF75D 3.619 3.426 4.544 2.233 2.233 2.233 −2.612 0.0292336 zinc finger protein 75D LPAR4 3.619 3.362 4.052 2.233 2.233 2.233 −2.612 0.0292925 lysophosphatidic acid receptor 4 ATG4A 3.619 3.996 4.362 2.233 3.043 2.233 −2.612 0.0384031 ATG4 autophagy related 4 homolog A (S. cerevisiae) ASH2L 3.619 3.693 4.142 2.951 2.233 2.233 −2.612 0.0456392 ash2 (absent, small, or homeotic)-like (Drosophila) C1orf115 3.619 4.224 2.991 2.233 2.233 2.233 −2.612 0.0497452 chromosome 1 open reading frame 115 PLEKHB2 9.079 9.720 9.566 8.183 8.095 8.182 −2.610 0.0395893 pleckstrin homology domain containing, family B (evectins) member 2 STARD4 4.008 3.878 2.894 2.625 1.648 1.648 −2.608 0.0405723 StAR-related lipid transfer (START) domain containing 4 HNRNPUL2 4.378 5.252 5.282 3.442 3.899 3.516 −2.608 0.0495026 heterogeneous nuclear ribonucleoprotein U-like 2 RHOA 11.864 11.400 11.735 10.484 10.114 10.030 −2.603 0.0281938 ras homolog gene family, member A GAA 7.591 7.302 6.882 5.502 6.138 6.034 −2.602 0.0431733 glucosidase, alpha; acid RPL22 11.036 11.640 11.304 9.766 9.881 10.265 −2.595 0.0383449 ribosomal protein L22 ARPP19 9.715 10.422 9.821 9.047 8.647 8.148 −2.594 0.0488378 cAMP-regulated phosphoprotein, 19 kDa TCF7L1 8.074 7.973 8.492 6.478 6.700 7.213 −2.593 0.0401189 transcription factor 7-like 1 (T-cell specific, HMG-box) C12orf35 3.947 4.406 4.343 2.970 2.970 2.970 −2.590 0.0376523 chromosome 12 open reading frame 35 RBBP4 8.145 8.760 9.177 7.453 7.238 7.387 −2.589 0.0487906 retinoblastoma binding protein 4 LYAR 6.001 7.069 6.594 4.632 5.351 5.230 −2.582 0.0424634 Ly1 antibody reactive homolog (mouse) RYK 7.895 7.194 7.431 6.294 6.264 5.831 −2.573 0.0390076 RYK receptor-like tyrosine kinase CRIP2 8.360 7.544 7.546 6.316 6.812 6.184 −2.567 0.0470707 cysteine-rich protein 2 FIBIN 5.992 4.324 4.240 2.970 3.508 2.970 −2.556 0.0445133 fin bud initiation factor homolog (zebrafish) RAB33B 5.019 5.494 5.845 4.099 4.141 4.146 −2.554 0.0424939 RAB33B, member RAS oncogene family ZNF292 6.828 6.286 6.970 5.259 4.935 5.690 −2.551 0.0420024 zinc finger protein 292 B4GALT3 8.065 8.656 8.614 7.351 6.372 7.267 −2.545 0.0441099 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3 CS 10.023 10.273 9.883 8.887 8.735 8.537 −2.543 0.0320607 citrate synthase RORC 4.008 2.926 4.097 1.648 1.648 2.752 −2.540 0.0414846 RAR-related orphan receptor C PRKD3 6.497 6.909 6.425 5.083 5.151 5.637 −2.535 0.0418451 protein kinase D3 RNF170 5.039 4.573 5.350 4.124 3.233 3.233 −2.531 0.0439497 ring finger protein 170 AGAP1 6.886 7.154 6.515 5.815 5.528 5.498 −2.528 0.0480711 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 PIGC 4.423 4.864 4.663 3.326 3.805 1.648 −2.527 0.0488052 phosphatidylinositol glycan anchor biosynthesis, class C C1orf128 8.123 9.487 8.690 7.416 6.993 7.363 −2.509 0.0437286 chromosome 1 open reading frame 128 MAPK1IP1L 8.223 8.626 8.672 7.146 7.345 6.983 −2.508 0.0338222 mitogen-activated protein kinase 1 interacting protein 1-like ATP1A1 10.412 10.973 11.413 9.658 9.478 9.647 −2.506 0.0472198 ATPase, Na+/K+ transporting, alpha 1 polypeptide TMOD4 3.194 1.753 1.973 0.648 0.648 0.648 −2.505 0.0352156 tropomodulin 4 (muscle) FBLN2 6.666 6.755 6.965 5.365 5.347 5.647 −2.495 0.0300766 fibulin 2 XYLT2 4.264 3.965 4.188 3.218 2.648 2.648 −2.492 0.0413383 xylosyltransferase II HAND2 4.620 4.588 4.311 2.648 3.294 3.303 −2.491 0.0337231 heart and neural crest derivatives expressed 2 ZNF304 4.620 4.443 4.675 3.718 2.648 3.303 −2.491 0.0480378 zinc finger protein 304 HNMT 7.403 6.197 5.862 4.556 5.089 5.005 −2.472 0.0432655 histamine N-methyltransferase UCHL5 3.792 3.951 4.662 2.648 2.648 2.648 −2.468 0.0318638 ubiquitin carboxyl-terminal hydrolase L5 FAM107B 8.072 8.765 8.185 6.771 7.286 7.050 −2.463 0.0467705 family with sequence similarity 107. member B ABCE1 6.940 8.349 6.885 5.891 5.720 5.592 −2.450 0.0382340 ATP-binding cassette, sub-family E (OABP), member 1 RAB37 3.422 2.936 2.625 1.648 1.648 1.648 −2.442 0.0394229 RAB37, member RAS oncogene family ZBTB48 5.109 5.331 5.422 4.052 4.151 3.508 −2.427 0.0352336 zinc finger and BTB domain containing 48 EARS2 5.076 4.623 4.705 3.797 3.508 2.970 −2.427 0.0417965 glutamyl-tRNA synthetase 2, mitochondrial (putative) RAB5B 9.640 9.423 9.394 8.391 7.830 8.145 −2.425 0.0328537 RAB5B, member RAS oncogene family RETSAT 7.036 6.574 7.136 5.859 5.371 5.654 −2.424 0.0441674 retinol saturase (all-trans-retinol 13,14-reductase) KLHL5 4.524 4.393 4.244 3.442 2.970 2.970 −2.418 0.0418222 kelch-like5 (Drosophila) PCBP4 6.566 6.299 6.117 4.248 5.026 5.387 −2.417 0.0441875 poly(rC) binding protein 4 ROR1 7.283 6.967 7.013 5.284 5.743 6.075 −2.411 0.0375761 receptor tyrosine kinase-like orphan receptor 1 VBP1 5.499 5.879 6.003 4.734 4.223 4.670 −2.409 0.0478790 von Hippel-Lindau binding protein 1 FAM164A 4.895 3.914 3.614 2.648 2.648 2.648 −2.404 0.0422423 family with sequence similarity 164, member A MRPL45 7.421 7.085 7.946 6.070 6.352 6.156 −2.402 0.0485834 mitochondrial ribosomal protein L45 TMEM158 7.488 7.628 7.738 6.480 5.583 6.364 −2.402 0.0347296 transmembrane protein 158 (gene/pseudogene) SAMD9L 4.264 3.910 3.706 2.648 2.648 2.648 −2.398 0.0355130 sterile alpha motif domain containing 9-like CRYL1 3.947 5.398 4.230 2.970 2.970 2.970 −2.395 0.0425473 crystallin, lambda 1 GSTP1 10.682 10.739 10.898 9.735 9.481 8.190 −2.391 0.0393965 glutathione S-transferase pi 1 FLOT1 8.583 8.085 7.975 7.139 7.033 6.719 −2.388 0.0483622 flotillin 1 CAPNS1 9.537 9.174 9.180 7.999 8.283 7.176 −2.384 0.0402984 calpain, small subunit 1 KLHL25 4.482 4.881 4.127 3.233 3.233 3.233 −2.377 0.0459407 kelch-like 25 (Drosophila) KIAA2013 8.407 7.627 7.662 6.582 6.645 6.378 −2.376 0.0415449 KIAA2013 RAB3GAP1 7.480 7.571 7.590 6.209 6.552 6.324 −2.372 0.0410263 RAB3 GTPase activating protein subunit 1 (catalytic) SSNA1 7.324 7.119 7.427 6.267 6.082 4.590 −2.364 0.0439269 Sjogren syndrome nuclear autoantigen 1 RGPD3 5.204 5.491 4.728 4.021 3.633 3.966 −2.358 0.0498714 RANBP2-like and GRIP domain containing 3 CSRP2BP 4.142 3.467 3.197 2.233 2.233 2.233 −2.352 0.0426437 CSRP2 binding protein CYB561D2 5.109 4.583 4.916 3.737 3.686 3.508 −2.345 0.0442464 cytochrome b-561 domain containing 2 LRP5 5.805 5.574 5.606 4.099 4.585 4.377 −2.343 0.0353224 low density lipoprotein receptor-related protein 5 GMCL1 4.194 2.522 2.868 1.648 1.648 1.648 −2.328 0.0495199 germ cell-less homolog 1 (Drosophila) C7orf42 11.106 11.171 10.732 9.900 9.924 9.605 −2.306 0.0481813 chromosome 7 open reading frame 42 C1orf126 6.419 5.979 6.024 4.989 4.827 4.796 −2.292 0.0377258 chromosome 1 open reading frame 126 PHF2 7.898 8.291 8.425 7.234 6.824 6.754 −2.283 0.0455400 PHD finger protein 2 TMEM200B 4.264 4.490 3.800 2.648 2.648 3.303 −2.276 0.0495740 transmembrane protein 200B PUF60 8.556 8.517 8.795 7.614 7.498 6.916 −2.267 0.0458998 poly-U binding splicing factor 60KDa ST6GAL1 5.377 5.739 5.424 4.579 4.273 3.303 −2.235 0.0462693 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 DCP1A 6.733 7.135 6.652 5.809 5.494 5.593 −2.231 0.0470867 DCP1 decapping enzyme homolog A (S. cerevisiae) CTDSPL 6.945 6.293 6.074 5.162 5.136 5.025 −2.231 0.0446277 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like RBM11 3.792 4.313 3.800 2.648 2.648 2.648 −2.222 0.0357334 RNA binding motif protein 11 EDIL3 3.792 3.925 3.674 2.648 2.648 2.648 −2.209 0.0408010 EGF-like repeats and discoidin l-like domains 3 GPD1L 3.792 3.765 3.781 2.648 2.648 2.648 −2.193 0.0349182 glycerol-3-phosphate dehydrogenase 1 -like TGM2 4.871 4.940 5.666 3.818 3.818 3.818 −2.176 0.0423588 transglutaminase 2 (C polypeptide, protein-glutamine-gamma- glutamyltransferase) CNNM2 7.893 7.772 7.912 6.815 6.657 6.671 −2.166 0.0406173 cyclin M2 GSTM5 3.792 3.747 3.639 2.648 2.648 2.648 −2.142 0.0454520 glutathione S-transferase mu 5 AQP7P3 3.194 1.649 1.719 0.648 0.648 0.648 −2.100 0.0496149 aquaporin 7 pseudogene 3 Higher Expression in Parous VSTM2L 1.648 1.648 1.689 2.625 2.739 2.752 2.089 0.0496059 V-set and transmembrane domain containing 2 like NDUFB1 1.648 1.648 1.648 2.625 2.739 2.752 2.130 0.0475667 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7k Da ZNF323 1.648 1.648 1.648 2.625 2.739 2.752 2.130 0.0475667 zinc finger protein 323 ALOXE3 1.648 1.648 1.689 2.625 2.739 3.294 2.130 0.0491809 arachidonate lipoxygenase 3 SLC24A2 1.648 1.648 1.648 3.326 2.739 2.752 2.149 0.0405529 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 CLIC6 1.648 1.648 1.648 2.625 3.247 2.752 2.149 0.0467501 chloride intracellular channel 6 POLB 1.648 1.648 1.648 2.625 3.247 2.752 2.149 0.0467501 polymerase (DNA directed), beta TRIM11 6.667 6.487 6.413 7.698 7.521 7.661 2.154 0.0486971 tripartite motif-containing 11 RRP15 5.869 5.847 5.770 6.965 7.071 6.852 2.171 0.0421591 ribosomal RNA processing 15 homolog (S. cerevisiae) WDR77 6.784 6.487 6.791 7.935 9.001 7.648 2.236 0.0446062 WD repeat domain 77 STK32C 4.142 2.822 4.395 5.167 5.314 5.451 2.254 0.0499941 serine/threonine kinase 32C CLPTM1 8.467 8.615 8.718 9.893 9.803 9.567 2.258 0.0463144 cleft lip and palate associated transmembrane protein 1 SFRS6 8.100 7.414 8.343 9.278 9.218 9.372 2.263 0.0455775 No description LOC400891 2.648 2.648 2.841 3.838 3.739 4.049 2.281 0.0441369 No description GAPVD1 7.485 7.322 7.499 8.683 8.413 8.792 2.294 0.0425764 GTPase activating protein and VPS9 domains 1 HNRPLL 7.069 6.751 6.876 8.076 7.872 8.717 2.298 0.0457875 heterogeneous nuclear ribonucleoprotein L-like FLJ13197 2.648 2.648 2.669 3.718 3.852 4.581 2.303 0.0388620 No description PIH1D1 7.411 7.423 7.232 9.807 8.370 8.615 2.303 0.0411539 PIH1 domain containing 1 AKIRIN2 9.442 9.240 9.445 10.448 10.485 10.973 2.309 0.0423282 akirin 2 ZNF709 4.744 3.481 4.380 5.599 5.562 5.682 2.327 0.0486679 zinc finger protein 709 XIST 8.848 9.100 9.339 10.318 10.330 10.503 2.345 0.0363726 X (inactive)-specific transcript (non-protein coding) SAPS3 8.256 7.990 8.127 9.357 9.039 9.980 2.345 0.0465251 No description MACC1 4.839 4.351 4.700 5.932 5.948 5.821 2.349 0.0376080 metastasis associated in colon cancer 1 C17orf77 2.233 2.233 2.233 3.429 3.467 4.174 2.352 0.0317640 chromosome 17 open reading frame 77 RPS17 12.815 12.592 12.922 14.158 13.999 13.951 2.355 0.0350471 ribosomal protein S17 EP400 6.915 6.974 6.349 7.847 7.974 8.224 2.378 0.0466672 E1A binding protein p400 RRAGD 5.482 6.357 5.276 7.612 7.505 6.529 2.386 0.0496808 Ras-related GTP binding D CLIC2 6.532 6.472 6.650 7.792 7.450 9.233 2.395 0.0479477 chloride intracellular channel 2 MAP3K4 4.792 6.450 6.412 7.714 7.432 7.678 2.404 0.0391109 mitogen-activated protein kinase kinase kinase 4 SFRS2IP 4.722 6.405 6.578 7.676 7.528 7.685 2.413 0.0422846 No description DLGAP3 2.233 2.233 2.607 4.276 3.467 3.508 2.420 0.0414000 discs, large (Drosophila) homolog-associated protein 3 PELP1 8.571 8.468 7.902 9.750 10.186 9.171 2.432 0.0492149 proline, glutamate and leucine rich protein 1 ABCF2 9.357 9.058 9.546 10.691 10.644 10.560 2.440 0.0339303 ATP-binding cassette, sub-family F (GCN20), member 2 DPP7 7.579 6.713 7.751 8.870 8.899 8.842 2.446 0.0340489 dipeptidyl-peptidase 7 MTA3 7.478 6.050 7.072 8.151 8.362 8.691 2.446 0.0450381 metastasis associated 1 family, member 3 GALNTL2 4.947 6.211 6.102 7.361 7.444 7.395 2.451 0.0324170 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N- acetylgalactosaminyltransferase-like 2 VEZF1 8.093 7.929 7.933 9.092 9.227 9.747 2.452 0.0350055 vascular endothelial zinc finger 1 SLC19A1 5.973 5.316 5.312 6.809 7.149 6.607 2.454 0.0459983 solute carrier family 19 (folate transporter), member 1 NKTR 7.130 7.218 7.727 9.380 8.428 8.481 2.459 0.0477133 natural killer-tumor recognition sequence C1orf144 7.347 7.878 7.768 9.277 9.066 8.585 2.459 0.0457965 chromosome 1 open reading frame 144 TAF1D 8.308 8.105 8.655 9.521 9.560 9.955 2.462 0.0394381 TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41 kDa REEP1 2.233 2.233 2.233 3.535 4.294 3.508 2.466 0.0276759 receptor accessory protein 1 HYAL3 2.233 2.233 2.524 3.535 4.413 3.508 2.466 0.0357016 hyaluronoglucosaminidase 3 GSDMA 5.908 5.730 5.820 7.164 6.969 7.211 2.467 0.0297598 gasdermin A ARHGEF2 7.154 7.163 7.778 8.464 8.568 8.990 2.478 0.0462783 Rho/Rac guanine nucleotide exchange factor (GEF) 2 BAZ2A 8.835 8.459 8.598 9.603 9.910 10.157 2.481 0.0437127 bromodomain adjacent to zinc finger domain, 2A RANBP2 5.232 5.625 5.272 6.592 6.484 7.121 2.496 0.0386943 RAN binding protein 2 ARRB2 4.378 4.231 3.697 5.555 4.970 6.026 2.504 0.0476156 arrestin, beta 2 OSTC 2.233 2.360 2.360 3.535 3.686 3.737 2.508 0.0257646 oligosaccharyltransferase complex subunit MRPS16 7.175 6.978 7.434 8.390 8.765 8.403 2.515 0.0360946 mitochondrial ribosomal protein S16 SFRS13A 7.065 7.809 7.828 8.571 9.163 9.139 2.522 0.0444315 No description PPP4C 5.773 5.356 5.494 7.106 7.059 6.691 2.522 0.0296648 protein phosphatase 4, catalytic subunit DEF8 7.271 7.301 7.466 8.639 8.239 8.836 2.529 0.0462873 differentially expressed in FDCP 8 homolog (mouse) SLAMF1 4.969 4.378 4.761 6.101 5.526 7.051 2.532 0.0483851 signaling lymphocytic activation molecule family member 1 TBKBP1 3.947 3.111 4.042 5.287 5.352 5.083 2.533 0.0314548 TBK1 binding protein 1 GOSR1 8.268 7.620 7.914 9.255 9.000 9.419 2.534 0.0438527 golgi SNAP receptor complex member 1 LOC401093 5.339 4.713 4.553 5.897 6.259 6.458 2.538 0.0468211 No description KIAA1530 5.854 5.193 5.747 6.893 7.093 7.184 2.542 0.0299976 KIAA1530 HSCB 5.861 6.081 6.537 7.429 7.290 7.816 2.547 0.0412315 HscB iron-sulfur cluster co-chaperone homolog (E. coli)) E4F1 3.818 3.818 3.938 5.344 5.167 4.807 2.547 0.0413002 E4F transcription factor 1 BID 6.431 7.249 7.403 8.354 8.756 8.544 2.555 0.0340662 BH3 interacting domain death agonist APOD 14.176 13.906 14.263 15.096 15.531 16.825 2.558 0.0387317 apolipoprotein D FAM40B 4.709 3.818 4.301 5.177 5.907 5.882 2.565 0.0491899 family with sequence similarity 40, member B KIAA1875 9.970 9.118 10.386 11.331 11.399 11.293 2.568 0.0390395 KIAA1875 UBE2Q1 6.984 6.270 6.257 8.301 8.346 7.328 2.570 0.0449945 ubiquitin-conjugating enzyme E2Q family member 1 VPS53 6.544 6.500 6.545 7.721 7.906 8.005 2.571 0.0258998 vacuolar protein sorting 53 homolog (S. cerevisiae) FBXL18 5.307 5.315 5.243 6.588 6.674 7.273 2.578 0.0245244 F-box and leucine-rich repeat protein 18 RNF145 8.597 9.051 8.392 9.738 9.972 10.420 2.583 0.0429903 ring finger protein 145 PURA 4.709 4.915 4.867 6.468 6.237 5.663 2.584 0.0463421 purine-rich element binding protein A TLN2 4.539 5.274 4.638 6.545 5.593 6.649 2.593 0.0486305 tal in 2 KDM1B 1.648 1.648 1.689 3.023 2.739 3.557 2.594 0.0323282 lysine (K)-specific demethylase 1B FAM186B 1.648 1.648 1.648 3.023 2.739 3.929 2.594 0.0330246 family with sequence similarity 186, member B ZDHHC19 1.648 1.648 1.648 3.023 2.739 3.929 2.594 0.0330246 zinc finger, DHHC-type containing 19 FPR3 1.648 1.648 1.648 3.023 2.739 4.493 2.594 0.0354270 formyl peptide receptor 3 MEFV 1.648 1.648 1.729 3.023 2.739 4.104 2.594 0.0357244 Mediterranean fever LOC55908 1.648 1.648 1.834 3.023 2.739 3.929 2.594 0.0377050 No description STK4 6.811 7.306 6.577 8.123 8.486 8.187 2.596 0.0386437 serine/threonine kinase 4 MIF4GD 5.264 5.281 4.154 6.315 6.040 6.659 2.598 0.0499553 MIF4G domain containing MRPS15 6.418 5.576 5.264 7.796 7.576 6.634 2.598 0.0450229 mitochondrial ribosomal protein S15 ADAMTS2 4.331 4.774 4.614 6.130 5.994 5.726 2.602 0.0315289 ADAM metallopeptidase with thrombospondin type 1 motif, 2 ADNP2 6.482 6.338 6.878 7.883 7.727 8.028 2.620 0.0372634 ADNP homeobox 2 MON1A 4.008 4.017 3.071 5.314 5.405 5.398 2.622 0.0251906 MON1 homolog A (yeast) MTMR10 7.747 6.113 7.310 8.908 8.462 8.704 2.628 0.0416038 myotubularin related protein 10 TCEA3 1.648 3.538 3.894 4.477 4.692 5.289 2.630 0.0494444 transcription elongation factor A (SH), 3 NCOR1 6.930 6.020 6.753 8.325 8.028 8.071 2.630 0.0286790 nuclear receptor corepressor 1 HDAC3 2.970 4.638 4.337 6.034 5.676 5.561 2.631 0.0343185 histone deacetylase 3 STRN4 8.435 7.238 9.030 9.588 10.045 9.832 2.632 0.0490839 striatin. calmodulin binding protein 4 KCTD2 6.906 6.770 6.930 8.302 8.361 8.091 2.632 0.0249841 potassium channel tetramerisation domain containing 2 ANKRD9 7.434 6.204 6.920 8.592 8.318 8.289 2.634 0.0362284 ankyrin repeat domain 9 C9or23 6.036 4.275 5.926 7.433 7.260 7.303 2.635 0.0292156 chromosome 9 open reading frame 23 POLD1 5.350 3.648 4.924 6.522 6.323 6.051 2.637 0.0420399 polymerase (DNA directed), delta 1, catalytic subunit 125 kDa CLDN15 3.422 4.493 4.613 5.653 5.983 5.893 2.638 0.0303622 claudin 15 PLCD3 8.813 8.430 8.918 9.959 10.008 10.318 2.639 0.0325064 phospholipase C, delta 3 PANX2 3.818 5.048 5.544 6.808 6.324 6.453 2.649 0.0373473 pannexin 2 CTSS 4.378 4.653 3.763 6.058 5.783 5.292 2.650 0.0422000 cathepsin S CCDC117 5.973 6.467 5.958 7.878 7.182 7.864 2.658 0.0317730 coiled-coil domain containing 117 ALDOA 12.092 11.705 12.543 13.955 13.558 13.025 2.661 0.0483761 aldolase A, fructose-bisphosphate FRY 5.503 5.013 4.034 6.600 6.428 6.074 2.667 0.0471615 furry homolog (Drosophila) TAOK2 6.879 6.347 7.174 7.992 8.590 8.197 2.668 0.0364267 TAO kinase 2 KLHDC4 3.792 3.793 4.273 4.981 5.948 5.210 2.670 0.0426707 kelch domain containing 4 FNIP1 7.114 7.739 7.748 9.166 8.638 9.104 2.673 0.0356787 folliculin interacting protein 1 SLC15A2 3.456 3.797 4.027 5.446 4.672 5.285 2.674 0.0428135 solute carrier family 15 (H+/peptide transporter), member 2 TEAD4 6.983 7.215 7.706 8.180 9.125 8.939 2.674 0.0435068 TEA domain family member 4 KIAA0892 7.858 7.518 7.700 9.604 9.122 8.649 2.681 0.0378971 No description DISP1 5.731 5.664 5.716 7.087 7.253 7.128 2.683 0.0188690 dispatched homolog 1 (Drosophila) BFAR 5.499 4.679 5.230 6.655 6.293 6.701 2.685 0.0376960 bifunctional apoptosis regulator MAPKSP1 6.179 7.654 7.534 8.598 9.083 8.743 2.693 0.0368308 MARK scaffold protein 1 ITCH 5.018 5.576 5.309 7.287 6.739 6.363 2.693 0.0352544 itchy E3 ubiquitin protein ligase homolog (mouse) GPATCH8 4.555 5.251 5.446 6.654 6.682 6.757 2.695 0.0252794 G patch domain containing 8 C16orf46 1.648 2.625 2.064 3.909 3.499 3.370 2.703 0.0373945 chromosome 16 open reading frame 46 SLC12A3 1.648 2.121 2.625 3.557 4.017 3.294 2.704 0.0389757 solute carrier family 12 (sodium/chloride transporters), member 3 MSH5 2.233 2.233 2.261 3.670 3.043 4.071 2.707 0.0460343 mutS homolog 5 (E. coli) TULP4 5.959 5.694 6.509 7.246 7.946 7.392 2.708 0.0374333 tubby like protein 4 AATF 4.969 6.655 6.358 7.921 7.803 7.540 2.723 0.0351310 apoptosis antagonizing transcription factor CLPB 2.648 2.648 2.744 5.512 4.097 3.897 2.729 0.0300586 CIpB caseinolytic peptidase B homolog (E. coli)) CLASP1 6.037 6.199 6.695 8.379 7.365 7.649 2.733 0.0402451 cytoplasmic linker associated protein 1 FAM48A 3.233 5.377 5.286 6.831 6.322 6.286 2.738 0.0439941 family with sequence similarity 48, member A CTDP1 6.570 5.610 6.244 7.699 7.977 7.307 2.742 0.0359740 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 RSL1D1 5.926 6.860 6.449 7.694 7.810 8.321 2.752 0.0344274 ribosomal L1 domain containing 1 CD55 7.788 9.110 8.391 10.066 9.644 9.853 2.755 0.0498860 CD55 molecule, decay accelerating factor for complement (Cromer blood group) PAQR7 8.661 6.715 7.963 9.426 9.457 9.285 2.756 0.0498236 progestin and adipoQ receptor family member VII KCTD13 6.949 6.092 6.502 8.238 8.048 7.555 2.757 0.0408496 potassium channel tetramerisation domain containing 13 TMBIM1 10.605 9.938 11.104 12.568 11.856 11.630 2.759 0.0497113 transmembrane BAX inhibitor motif containing 1 DHX9 7.842 8.345 8.547 9.726 9.681 10.012 2.759 0.0253064 DEAH (Asp-Glu-Ala-His) box polypeptide 9 PPAPDC2 4.708 3.511 3.456 6.016 5.659 4.920 2.760 0.0426236 phosphatidic acid phosphatase type 2 domain containing 2 RNF40 5.291 4.799 4.993 6.882 6.347 6.265 2.761 0.0307144 ring finger protein 40 TTC38 5.039 4.897 4.602 6.512 6.073 6.068 2.762 0.0338014 tetratricopeptide repeat domain 38 PLSCR2 4.142 3.197 3.521 4.664 4.875 5.927 2.766 0.0475373 phospholipid scramblase 2 PARN 6.667 6.258 6.284 8.638 7.753 7.226 2.768 0.0489813 poly(A)-specific ribonuclease (deadenylation nuclease) RNPC3 2.970 3.953 4.268 5.626 5.427 5.421 2.777 0.0260274 RNA-binding region (RNP1, RRM) containing 3 MYLK3 5.171 4.686 4.734 6.378 5.894 6.646 2.780 0.0352003 myosin light chain kinase 3 TFRC 7.644 8.124 8.172 9.119 10.128 9.600 2.782 0.0284010 transferrin receptor (p90, CD71) TSC1 4.722 5.588 5.524 6.687 6.539 7.067 2.788 0.0363227 tuberous sclerosis 1 CSK 8.824 8.571 8.905 10.311 10.387 9.801 2.794 0.0329154 c-src tyrosine kinase COX10 2.970 3.820 3.272 4.907 5.182 4.453 2.795 0.0364017 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) FZR1 5.988 5.623 6.082 7.352 7.443 7.564 2.795 0.0206783 fizzy/cell division cycle 20 related 1 (Drosophila) WDR44 6.011 5.482 5.965 6.965 7.126 7.959 2.796 0.0359830 WD repeat domain 44 NINL 2.233 2.461 2.385 3.871 3.467 4.230 2.800 0.0284593 ninein-like C17orf68 4.539 5.250 5.598 6.740 6.575 6.904 2.807 0.0289231 chromosome 17 open reading frame 68 NME4 7.076 6.479 7.507 8.872 8.565 8.078 2.808 0.0420558 non-metastatic cells 4, protein expressed in ZNF121 2.970 3.601 3.626 5.208 5.094 4.405 2.815 0.0360399 zinc finger protein 121 SLC25A10 3.792 3.791 3.533 5.599 5.189 5.026 2.815 0.0227574 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 SEP9 11.830 10.336 11.508 13.324 12.827 12.298 2.817 0.0486076 septin 9 ZNF276 5.828 5.364 5.729 6.659 7.224 7.475 2.820 0.0334229 zinc finger protein 276 SUV420H1 4.793 4.984 4.530 5.822 6.294 6.702 2.830 0.0321972 suppressor of variegation 4-20 homolog 1 (Drosophila) ALPK3 3.818 4.229 5.062 6.408 5.658 5.732 2.833 0.0411095 alpha-kinase 3 TMEM63C 2.233 2.233 2.702 3.429 4.777 3.737 2.836 0.0388960 transmembrane protein 63C LOC100128239 2.233 2.233 2.360 3.737 3.043 4.071 2.836 0.0480218 No description USP8 6.608 6.345 6.173 8.152 7.678 7.806 2.839 0.0252523 ubiquitin specific peptidase 8 SLC4A2 6.110 6.934 6.032 8.382 7.539 7.636 2.843 0.0427345 solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) ATG2B 5.047 5.479 5.440 7.054 6.225 6.948 2.844 0.0393182 ATG2 autophagy related 2 homolog B (S. cerevisiae) BCAT2 7.598 6.436 7.770 8.585 8.519 9.279 2.846 0.0488849 branched chain amino-acid transaminase 2, mitochondrial RACGAP1 4.972 5.253 5.411 6.329 6.764 7.873 2.850 0.0303144 Rac GTPase activating protein 1 AGGF1 4.086 3.907 3.577 5.607 5.089 5.159 2.853 0.0318548 angiogenic factor with G patch and FHA domains 1 KLF8 5.499 6.084 5.219 7.345 6.732 7.574 2.855 0.0308163 Kruppel-like factor 8 ASAP2 5.659 5.419 5.367 7.123 6.881 7.028 2.856 0.0193002 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 ACADS 5.552 5.021 4.968 7.562 6.151 6.535 2.857 0.0428641 acyl-CoA dehydrogenase, C-2 to C-3 short chain CCNL1 9.165 8.693 9.269 10.209 10.543 11.090 2.859 0.0301348 cyclin L1 PDCD11 5.789 6.630 6.003 7.519 8.050 7.483 2.860 0.0317549 programmed cell death 11 BAT2L1 10.283 9.736 10.620 11.636 11.799 11.889 2.860 0.0274825 No description METTL11A 8.098 7.645 6.873 9.347 9.163 9.077 2.864 0.0292246 methyltransferase like 11A IVD 5.151 5.173 5.511 7.140 6.692 6.341 2.865 0.0340399 isovaleryl-CoA dehydrogenase FTSJ3 6.072 6.940 6.692 8.212 7.638 8.234 2.867 0.0388468 FtsJ homolog 3 (E. coli)) STMN1 7.744 7.043 8.225 8.633 9.264 9.614 2.868 0.0476981 stathmin 1 PRIC285 4.108 4.108 5.161 5.628 6.271 6.375 2.868 0.0348475 No description DKFZp686O241 2.648 3.630 2.971 4.697 4.168 4.781 2.868 0.0406499 No description 66 DRAM1 6.252 6.833 6.649 8.218 7.615 8.355 2.871 0.0335158 DNA-damage regulated autophagy modulator 1 RPS10 2.970 2.970 2.970 4.492 5.005 4.327 2.872 0.0202562 ribosomal protein S10 ZNF558 1.648 4.874 4.305 6.398 5.646 5.459 2.874 0.0425029 zinc finger protein 558 SSR2 10.361 9.031 9.571 11.886 11.011 10.845 2.878 0.0449203 signal sequence receptor, beta (translocon-associated protein beta) RHBDD3 6.103 4.910 5.549 7.132 7.074 6.925 2.879 0.0362562 rhomboid domain containing 3 LOC92659 7.036 6.105 6.924 8.124 8.131 8.562 2.881 0.0304260 No description C17orf73 5.952 5.238 6.365 7.382 7.585 7.479 2.882 0.0284683 chromosome 17 open reading frame 73 RAB4A 6.985 6.914 6.499 7.787 8.696 8.442 2.885 0.0339934 RAB4A, member RAS oncogene family HIVEP1 5.938 5.230 3.984 6.657 6.209 7.467 2.886 0.0496648 human immunodeficiency virus type I enhancer binding protein 1 TMPRSS11B 4.647 4.728 4.647 6.177 5.544 6.636 2.889 0.0394471 transmembrane protease, serine 11B ABCF3 6.167 6.279 6.927 7.726 7.967 7.811 2.891 0.0381175 ATP-binding cassette, sub-family F (GCN20), members OTX2OS1 2.970 3.111 3.627 4.753 4.508 5.006 2.903 0.0283248 No description MTAP 5.596 5.752 5.956 7.291 7.421 7.266 2.906 0.0182340 methylthioadenosine phosphorylase B3GALT4 0.648 3.431 3.664 4.972 5.196 4.901 2.909 0.0289522 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 MFSD5 6.647 6.487 6.542 8.548 8.084 7.809 2.911 0.0236107 major facilitator superfamily domain containing 5 PRDM1 8.044 7.835 8.686 9.450 9.377 11.740 2.912 0.0409341 PR domain containing 1, with ZNF domain MARK4 7.556 6.924 7.134 8.534 9.429 8.471 2.922 0.0316399 MAP/microtubule affinity-regulating kinase 4 C21 orf94 1.648 2.625 1.648 3.023 4.174 3.557 2.926 0.0399109 chromosome 21 open reading frame 94 SERPINB6 9.001 7.279 8.682 10.551 9.675 9.829 2.928 0.0445730 serpin peptidase inhibitor, clade B (ovalbumin), member 6 MED19 7.923 7.618 6.593 9.473 8.740 9.140 2.928 0.0306867 mediator complex subunit 19 LILRB1 5.908 5.281 5.768 7.013 6.889 7.459 2.929 0.0321487 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 ZNF7 2.648 2.648 2.744 4.883 3.852 4.199 2.930 0.0264163 zinc finger protein 7 C20orf12 2.648 3.791 2.669 4.883 4.405 4.199 2.930 0.0494222 chromosome 20 open reading frame 12 INPP4A 6.624 6.013 6.693 7.558 8.176 8.801 2.931 0.0287296 inositol polyphosphate-4-phosphatase, type I, 107 kDa LOC399815 0.648 0.648 1.245 2.202 2.353 2.370 2.935 0.0286652 No description REXO2 8.671 8.407 8.598 10.163 10.152 10.005 2.936 0.0174180 REX2, RNA exonuclease 2 homolog (S. cerevisiae) SEC22B 7.781 6.370 7.186 9.335 8.555 8.286 2.936 0.0443296 SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) UBE3B 4.331 4.853 4.518 6.453 5.726 6.072 2.937 0.0294458 ubiquitin protein ligase E3B TATDN3 3.792 4.595 5.221 6.731 6.151 5.608 2.939 0.0440551 TatD DNase domain containing 3 STX4 9.151 8.902 9.909 10.710 10.457 11.201 2.939 0.0430596 syntaxin 4 ZSWIM7 4.086 3.771 4.526 5.883 5.957 5.327 2.940 0.0277217 zinc finger, SWIM-type containing 7 RELB 9.095 8.137 9.548 10.682 10.224 10.653 2.944 0.0391511 v-rel reticuloendotheliosis viral oncogene homolog B FAU 13.231 12.684 13.522 14.789 14.877 14.790 2.946 0.0213716 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed ATG4B 7.995 7.016 8.090 9.473 9.259 9.649 2.947 0.0243151 ATG4 autophagy related 4 homolog B (S. cerevisiae) FIP1L1 4.378 3.812 5.028 5.561 6.489 5.944 2.961 0.0393272 FIP1 like 1 (S. cerevisiae) ASH1L 6.835 6.410 6.898 8.401 7.876 8.793 2.961 0.0259594 ash1 (absent, small, or homeotic)-like (Drosophila) HUNK 6.608 4.782 5.803 7.652 7.285 7.370 2.963 0.0393023 hormonally up-regulated Neu-associated kinase RGS14 6.070 3.983 4.142 5.551 7.245 7.357 2.966 0.0473841 regulator of G-protein signaling 14 POM121L10P 4.439 4.190 4.418 5.240 6.019 5.987 2.968 0.0380530 POM121 membrane glycoprotein-like 10, pseudogene PMS2 5.400 5.253 5.830 6.915 7.432 6.823 2.969 0.0266915 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) PPP3CC 8.154 6.987 7.252 9.393 8.847 8.557 2.970 0.0488142 protein phosphatase 3, catalytic subunit, gamma isozyme SLC25A26 7.687 7.081 6.838 8.413 9.035 8.741 2.978 0.0324842 solute carrier family 25, member 26 ZNF208 3.456 4.501 4.579 5.960 6.154 5.644 2.979 0.0266735 zinc finger protein 208 ACY1 6.967 5.414 6.580 7.976 8.541 7.471 2.979 0.0432010 aminoacylase 1 DGKD 6.918 6.451 7.219 8.027 9.050 8.152 2.981 0.0380371 diacylglycerol kinase, delta 130 kDa C20orf29 4.620 4.492 4.025 7.547 6.068 5.501 2.983 0.0296163 chromosome 20 open reading frame 29 LOC150381 5.598 4.017 5.384 6.965 7.067 6.261 2.993 0.0365425 No description PPAN 6.829 5.591 6.631 7.502 8.411 7.796 2.995 0.0449799 peter pan homolog (Drosophila) CASP9 6.470 3.431 6.071 7.391 7.580 8.053 2.996 0.0323532 caspase 9, apoptosis-related cysteine peptidase ZNF625 4.008 3.544 4.835 6.065 5.591 5.289 2.997 0.0451088 zinc finger protein 625 XRCC3 2.648 2.822 3.298 4.883 4.784 3.897 2.999 0.0326929 X-ray repair complementing defective repair in Chinese hamster cells 3 SHROOM3 6.343 6.369 7.229 7.954 9.858 7.750 3.000 0.0430319 shroom family member 3 TNFRSF9 3.947 4.342 3.572 5.532 4.884 6.111 3.002 0.0400641 tumor necrosis factor receptor superfamily, member 9 ZFYVE26 3.648 4.055 3.976 5.920 5.103 5.565 3.010 0.0241757 zinc finger, FYVE domain containing 26 DENND5A 9.235 8.563 7.907 10.153 9.903 10.649 3.011 0.0341730 DENN/MADD domain containing 5A HTT 7.683 6.819 6.715 8.409 8.316 8.590 3.011 0.0467858 huntingtin RNF207 4.214 4.176 3.649 5.769 4.664 6.222 3.015 0.0490319 ring finger protein 207 MEGF8 5.640 4.920 5.257 7.277 6.850 6.329 3.016 0.0342887 multiple EGF-like-domains 8 PRPF4 6.177 6.291 6.860 8.453 7.943 7.766 3.016 0.0267567 PRP4 pre-mRNA processing factor 4 homolog (yeast) FAM184B 8.832 8.406 9.347 10.013 10.057 10.940 3.017 0.0455913 family with sequence similarity 184, member B GVIN1 1.648 1.648 1.648 3.023 3.247 3.929 3.029 0.0196482 No description RIMS1 1.648 1.648 1.834 3.830 3.247 2.752 3.029 0.0307754 regulating synaptic membrane exocytosis 1 C10orf111 1.648 1.648 1.648 2.625 3.247 3.929 3.029 0.0320416 chromosome 10 open reading frame 111 LOC100272228 1.648 1.648 1.648 2.625 3.247 3.929 3.029 0.0320416 No description RABL2B 1.648 1.648 1.648 2.625 3.247 4.104 3.029 0.0323920 RAB, member of RAS oncogene family-like 2B APOBEC3H 1.648 1.648 1.689 2.625 3.247 4.236 3.029 0.0336912 apolipoprotein B mRNA editing enzyme, catalytic polypeptide- like 3H ZNF134 1.648 2.926 1.834 4.405 3.247 3.929 3.029 0.0364357 zinc finger protein 134 CDKN2BAS 1.648 1.879 1.648 2.625 3.247 3.929 3.029 0.0378139 No description RAD1 5.504 5.439 4.802 6.686 7.103 6.642 3.031 0.0274347 RAD1 homolog (S. pombe) ATMIN 6.777 5.638 6.303 8.345 7.905 7.668 3.036 0.0266305 ATM interactor MYH14 4.378 4.859 5.401 6.163 8.754 5.981 3.038 0.0445972 myosin, heavy chain 14, non-muscle ADNP 5.830 6.785 7.054 8.300 8.005 8.660 3.045 0.0270506 activity-dependent neuroprotector homeobox SLC43A1 5.645 4.992 6.160 7.253 6.441 7.821 3.047 0.0485633 solute carrier family 43, member 1 GRPEL1 8.296 8.985 7.879 9.487 10.132 10.039 3.047 0.0409965 GrpE-like 1, mitochondrial (E. coll) G8orf80 4.086 5.261 5.129 6.869 6.133 6.730 3.048 0.0288697 chromosome 8 open reading frame 80 YRDC 6.418 5.530 6.156 8.027 7.731 7.356 3.050 0.0259733 yrdC domain containing (E. coli)) FAM189B 6.283 5.852 7.238 8.286 7.893 7.702 3.052 0.0469820 family with sequence similarity 189, member B HUWE1 7.381 7.777 7.658 9.194 9.267 9.316 3.052 0.0154672 HECT, UBA and WWE domain containing 1 MURC 2.970 3.406 3.552 4.580 4.611 6.377 3.052 0.0342977 muscle-related coiled-coil protein PER1 9.994 9.518 11.227 12.348 11.128 12.457 3.053 0.0479948 period homolog 1 (Drosophila) UBE2G2 7.961 8.575 9.061 10.118 10.398 10.186 3.054 0.0248322 ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) TRIM8 10.354 9.527 8.853 11.372 10.465 11.809 3.057 0.0489168 tripartite motif-containing 8 ZC3H18 6.349 5.474 5.872 7.484 7.481 7.749 3.058 0.0228218 zinc finger CCCH-type containing 18 SUV420H2 4.709 4.778 5.202 6.391 6.265 8.186 3.060 0.0272683 suppressor of variegation 4-20 homolog 2 (Drosophila) MRPL4 4.904 6.619 6.642 8.100 8.256 8.148 3.061 0.0225584 mitochondrial ribosomal protein L4 MINA 6.769 5.963 4.690 7.618 7.474 7.579 3.066 0.0417646 MYO induced nuclear antigen USH1G 2.648 3.540 4.170 4.446 5.576 5.156 3.066 0.0481633 Usher syndrome 1G (autosomal recessive) MLXIPL 4.620 5.199 5.342 6.240 6.494 7.114 3.073 0.0328218 MLX interacting protein-like XPO4 3.818 5.143 4.674 6.296 6.513 5.687 3.077 0.0387643 exportin 4 C1orf21 8.738 7.810 7.911 9.452 9.533 9.781 3.078 0.0395102 chromosome 1 open reading frame 21 NLRP1 5.553 4.482 4.498 6.146 6.104 6.719 3.079 0.0453411 NLR family, pyrin domain containing 1 L2HGDH 5.401 6.855 6.598 8.101 8.221 8.357 3.080 0.0224586 L-2-hydroxyglutarate dehydrogenase ZNF529 4.805 5.003 4.522 5.528 6.626 6.511 3.081 0.0453321 zinc finger protein 529 HCN2 2.233 2.524 2.991 3.278 4.151 6.439 3.089 0.0494825 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 CCDC86 7.746 8.085 7.722 9.274 10.300 9.375 3.092 0.0221154 coiled-coil domain containing 86 CARD6 8.671 8.373 8.847 10.299 10.097 10.316 3.093 0.0186853 caspase recruitment domain family, member 6 BET1L 5.107 4.770 5.011 7.734 6.399 6.608 3.094 0.0206153 blocked early in transport 1 homolog (S. cerevisiae)-like RAH 8.282 7.633 8.036 9.070 9.666 9.993 3.096 0.0301945 retinoic acid induced 1 ZNF579 5.539 5.892 5.723 7.172 7.523 7.296 3.099 0.0178541 zinc finger protein 579 TMEM63B 6.873 6.815 8.065 8.448 9.214 9.128 3.101 0.0359040 transmembrane protein 63B WDR19 2.970 5.666 5.090 6.970 6.422 6.724 3.103 0.0349744 WD repeat domain 19 BPNT1 11.316 10.810 10.888 13.080 12.419 12.525 3.109 0.0222977 3′(2′), 5′-bisphosphate nucleotidase 1 ANKS3 4.895 5.008 6.025 7.075 7.264 6.535 3.117 0.0336073 ankyrin repeat and sterile alpha motif domain containing 3 USP35 2.233 2.932 2.949 4.276 3.958 4.590 3.119 0.0292066 ubiquitin specific peptidase 35 TCTEX1D4 1.648 1.648 2.121 4.376 3.247 3.294 3.130 0.0238014 Tctex1 domain containing 4 EXOC6B 1.648 1.648 1.648 3.830 2.739 3.294 3.130 0.0266825 exocyst complex component 6B CR1 1.648 2.304 2.834 5.056 3.805 3.294 3.130 0.0404211 complement component (3b/4b) receptor 1 (Knops blood group) FXYD2 4.580 3.558 4.094 6.343 5.741 4.838 3.132 0.0497023 FXYD domain containing ion transport regulator 2 E2F2 2.648 2.904 3.424 5.072 4.405 4.346 3.133 0.0286998 E2F transcription factor 2 THAP7 6.570 7.334 4.575 8.788 8.221 7.742 3.139 0.0396267 THAP domain containing 7 CYTH2 9.298 8.475 8.275 10.127 10.403 10.024 3.142 0.0363137 cytohesin 2 APOOL 6.036 5.272 5.736 7.516 6.812 7.688 3.144 0.0279601 apolipoprotein O-like ZNF662 3.947 4.464 3.694 5.600 5.507 5.708 3.146 0.0249598 zinc finger protein 662 ZFPM1 6.017 4.661 5.034 7.002 7.602 6.320 3.157 0.0376821 zinc finger protein, multitype 1 DHX37 5.322 6.087 6.981 7.748 8.564 7.410 3.161 0.0381355 DEAH (Asp-Glu-Ala-His) box polypeptide 37 AFMID 3.456 4.706 4.501 5.476 5.669 6.370 3.170 0.0401425 arylformamidase GCDH 6.167 5.264 5.587 7.796 7.359 6.929 3.172 0.0274166 glutaryl-CoA dehydrogenase GJB2 2.648 3.507 3.603 5.173 5.778 4.199 3.173 0.0343490 gap junction protein, beta 2. 26 kDa C19orf44 4.264 3.747 4.503 6.268 5.414 5.881 3.176 0.0256787 chromosome 19 open reading frame 44 SYNRG 4.839 5.151 5.883 6.470 6.822 7.700 3.184 0.0346007 synergin, gamma PDIA3 5.503 4.480 5.055 7.181 6.151 6.293 3.185 0.0440641 protein disulfide isomerase family A, member 3 LOC284276 2.233 2.233 2.261 4.151 3.043 3.905 3.186 0.0403075 No description TMEM184B 7.419 7.045 7.654 9.290 9.091 8.810 3.188 0.0193182 transmembrane protein 184B DNASE1 4.817 5.045 5.178 6.719 6.562 6.748 3.190 0.0152184 deoxyribonuclease I TRPM7 5.854 6.415 6.498 7.739 7.562 8.171 3.190 0.0273217 transient receptor potential cation channel, subfamily M, member 7 CEACAM5 7.977 7.296 8.209 9.513 9.514 9.883 3.190 0.0190860 carcinoembryonic antigen-related cell adhesion molecule 5 FOXO1 8.791 8.733 8.167 10.730 9.386 10.407 3.191 0.0387033 forkhead box O1 CUL2 6.227 5.758 6.063 7.593 7.776 7.738 3.195 0.0156406 cullin 2 SLAMF6 1.648 1.648 1.648 3.326 3.247 3.746 3.199 0.0131414 SLAM family member 6 LRRC33 1.648 1.648 2.234 3.326 2.739 4.692 3.199 0.0426035 leucine rich repeat containing 33 CENPBD1 1.648 1.978 3.023 3.326 3.805 4.104 3.199 0.0475282 CENPB DNA-binding domains containing 1 NMUR1 4.214 4.213 4.672 5.696 6.350 6.051 3.199 0.0214783 neuromedin U receptor 1 STK11 6.842 5.878 6.936 8.237 8.274 8.615 3.202 0.0218305 serine/threonine kinase 11 MLL4 7.243 6.378 7.090 8.174 8.926 8.584 3.210 0.0277064 No description SMC1A 5.775 6.451 6.264 8.238 7.946 7.268 3.210 0.0283920 structural maintenance of chromosomes 1A FLJ44635 0.648 2.359 2.714 3.351 4.043 4.262 3.213 0.0339754 No description SETMAR 3.619 4.495 4.417 6.015 6.181 5.571 3.216 0.0235927 SET domain and mariner transposase fusion gene C2orf68 6.917 6.672 5.737 8.603 8.162 8.109 3.218 0.0227192 chromosome 2 open reading frame 68 CD58 4.264 4.738 4.170 5.985 5.608 6.424 3.218 0.0265147 CD58 molecule ANKRD13B 5.941 6.297 6.410 7.169 8.134 7.986 3.224 0.0332114 ankyrin repeat domain 13B ARGFX 3.648 3.821 3.887 5.901 5.430 5.338 3.225 0.0151934 arginine-fifty homeobox SERPINC1 2.233 3.737 2.461 4.151 4.151 4.791 3.226 0.0493140 serpin peptidase inhibitor, clade C (antithrombin), member 1 MCCC2 7.579 6.220 6.526 8.762 8.715 7.911 3.229 0.0368752 methylcrotonoyl-CoA carboxylase 2 (beta) SPATA5L1 4.423 3.645 4.751 5.731 6.443 5.926 3.231 0.0256877 spermatogenesis associated 5-like 1 ANKLE1 5.633 5.912 5.059 7.389 6.718 7.606 3.234 0.0269168 ankyrin repeat and LEM domain containing 1 PPOX 2.648 2.768 2.921 3.897 4.618 4.579 3.241 0.0250201 protoporphyrinogen oxidase SF3B4 9.275 8.976 8.460 10.999 10.391 10.161 3.250 0.0301258 splicing factor 3b, subunit 4, 49 kDa LOC339047 1.648 4.117 4.797 4.931 5.818 6.428 3.252 0.0447421 No description IRX1 6.103 6.586 7.024 8.288 10.744 7.688 3.253 0.0330471 iroquois homeobox 1 NUP214 5.731 6.834 5.991 7.693 7.680 7.850 3.253 0.0329993 nucleoporin 214 kDa SULT1B1 0.648 0.648 0.648 2.202 2.353 3.043 3.259 0.0151754 sulfotransferase family, cytosolic, 1B, member 1 MUC2 0.648 0.648 0.648 2.202 2.353 3.351 3.259 0.0164180 mucin 2. oligomeric mucus/gel-forming NAPSA 0.648 0.648 0.648 2.202 2.353 3.351 3.259 0.0164180 napsin A aspartic peptidase OXNAD1 0.648 0.648 1.245 2.714 2.353 2.370 3.259 0.0222735 oxidoreductase NAD-binding domain containing 1 RNF216 6.091 6.137 6.823 8.118 8.260 7.797 3.261 0.0215484 ring finger protein 216 PTCD3 6.164 6.507 6.655 7.707 8.737 8.214 3.263 0.0220073 Pentatricopeptide repeat domain 3 SNAPC4 4.378 4.937 5.888 6.644 7.273 6.492 3.264 0.0344503 small nuclear RNA activating complex, polypeptide 4, 190 kDa RPTOR 6.229 4.543 6.506 7.705 8.213 7.247 3.264 0.0334589 regulatory associated protein of MTOR, complex 1 ATP6VOD2 6.930 6.193 7.063 8.637 8.669 8.630 3.264 0.0148218 ATPase, H+ transporting, lysosomal 38 kDa, VO subunit d2 ODF3B 6.756 6.358 7.577 8.232 8.738 8.465 3.268 0.0355380 outer dense fiber of sperm tails 3B ZNF530 2.233 2.814 3.067 4.276 4.523 4.777 3.270 0.0180239 zinc finger protein 530 TNFSF10 9.745 8.439 9.283 10.993 10.919 11.285 3.272 0.0206402 tumor necrosis factor (ligand) superfamily, member 10 PSPN 0.648 2.552 3.664 4.262 4.043 5.343 3.272 0.0362132 persephin RBM23 8.040 6.513 7.729 9.750 9.204 9.103 3.272 0.0254471 RNA binding motif protein 23 DNAJB13 2.233 2.565 2.951 4.276 5.017 3.737 3.273 0.0278471 DnaJ (Hsp40) homolog, subfamily B, member 13 LSG1 4.793 3.456 3.951 5.438 5.662 6.144 3.274 0.0332669 large subunit GTPase 1 homolog (S. cerevisiae) ZNF251 4.142 4.437 2.233 5.943 5.458 5.853 3.274 0.0269785 zinc finger protein 251 SIRT3 10.236 9.525 10.552 11.948 12.013 11.655 3.276 0.0219435 sirtuin 3 RRAGA 9.875 8.646 8.913 11.448 10.626 10.450 3.277 0.0355289 Ras-related GTP binding A PLEKHF1 7.603 6.757 7.376 8.471 9.450 8.992 3.282 0.0266215 pleckstrin homology domain containing, family F (with FYVE domain) member 1 POMGNT1 7.181 5.688 6.450 8.873 8.359 7.403 3.282 0.0403615 protein O-linked mannose beta1,2-N- acetylglucosaminyltransferase ATAD3A 5.598 5.803 7.021 7.827 8.042 7.313 3.283 0.0445563 ATPase family, AAA domain containing 3A MTPAP 9.214 9.010 10.030 10.886 11.029 10.929 3.284 0.0328128 mitochondrial poly(A) polymerase PRRX2 9.669 7.471 9.079 10.588 10.150 11.385 3.286 0.0379539 paired related homeobox 2 ZFAT 3.947 3.937 3.655 6.345 4.797 5.654 3.287 0.0302908 zinc finger and AT hook domain containing SIRT7 4.972 6.198 5.754 6.792 7.564 7.472 3.288 0.0356454 sirtuin 7 EIF2B4 6.732 7.193 6.769 8.911 8.767 8.402 3.291 0.0154582 eukaryotic translation initiation factor 2B, subunit 4 delta, 67 kDa TDRD7 3.792 3.520 3.402 5.715 4.499 5.239 3.292 0.0343400 tudor domain containing 7 KIAA0355 8.189 7.198 8.193 9.914 9.750 9.641 3.296 0.0178166 KIAA0355 EIF4G1 7.677 7.179 7.946 9.399 9.677 8.783 3.299 0.0264607 eukaryotic translation initiation factor 4 gamma, 1 MOV10L1 0.648 0.648 0.729 2.202 4.043 2.370 3.299 0.0201549 Mov1011, Moloney leukemia virus 10-like 1, homolog (mouse) KIAA0101 0.648 0.648 0.648 2.202 4.428 2.370 3.299 0.0211109 KIAA0101 ZNF167 3.194 0.648 0.648 4.748 4.602 2.370 3.299 0.0392211 zinc finger protein 167 LMTK2 7.232 7.617 7.829 9.120 9.340 9.386 3.301 0.0166097 lemur tyrosine kinase 2 DNAJC9 4.142 3.665 3.448 5.661 5.807 5.172 3.303 0.0185979 DnaJ (Hsp40) homolog, subfamily C, member 9 RAB2B 5.229 4.693 5.308 6.953 6.521 6.965 3.303 0.0186430 RAB2B, member RAS oncogene family PIWIL4 2.233 2.233 2.570 3.535 3.958 5.147 3.306 0.0270596 piwi-like 4 (Drosophila) TFIP11 6.689 7.447 7.025 8.869 8.750 8.538 3.307 0.0212600 tuftelin interacting protein 11 POLR2I 5.781 5.820 6.204 7.848 7.930 6.706 3.308 0.0395650 polymerase (RNA) II (DNA directed) polypeptide I, 14.5 kDa HM13 7.766 6.884 7.285 9.627 9.013 8.292 3.311 0.0358811 histocompatibility (minor) 13 FASN 6.635 7.122 7.637 8.574 8.997 8.850 3.313 0.0251137 fatty acid synthase NNT 2.233 2.712 3.063 4.791 4.413 4.082 3.314 0.0218756 nicotinamide nucleotide transhydrogenase ACAP1 4.086 4.482 4.876 6.001 5.816 8.251 3.316 0.0301785 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 TEX264 8.285 6.089 7.621 9.828 9.154 9.351 3.318 0.0269938 testis expressed 264 RAB17 1.648 2.744 3.077 4.477 4.811 4.376 3.326 0.0181127 RAB17, member RAS oncogene family BAT3 10.663 9.409 9.727 12.184 11.676 11.144 3.329 0.0328870 No description SYN2 4.619 3.233 4.018 5.001 6.049 5.755 3.332 0.0410763 synapsin II DPYSL4 6.689 5.247 5.945 7.029 7.683 7.997 3.336 0.0435407 dihyd ropyrimidinase-like 4 GALNT6 4.086 4.622 4.425 6.163 6.479 5.260 3.336 0.0357757 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N- acetylgalactosaminyltransferase 6 (GalNAc-T6) RHBDL1 2.233 4.224 3.520 5.003 5.017 5.963 3.339 0.0307234 rhomboid, veinlet-like 1 (Drosophila) POLH 6.335 7.220 6.917 8.659 8.522 8.927 3.344 0.0162582 polymerase (DNA directed), eta HOXC8 7.681 5.653 5.210 9.425 6.736 9.169 3.349 0.0476572 homeobox C8 LYPD3 5.572 5.879 6.430 7.317 9.532 7.566 3.352 0.0277355 LY6/PLAUR domain containing 3 FBXL6 4.817 3.815 2.932 5.909 5.561 5.451 3.354 0.0358388 F-box and leucine-rich repeat protein 6 RUFY1 6.818 5.569 6.004 8.037 7.750 7.573 3.355 0.0308364 RUN and FYVE domain containing 1 XRCC2 9.450 8.940 9.978 11.299 10.688 11.235 3.360 0.0306125 X-ray repair complementing defective repair in Chinese hamster cells 2 SLC35C2 7.052 5.990 6.798 9.582 8.056 7.742 3.368 0.0385730 solute carrier family 35, member C2 CENPT 6.713 7.013 7.984 8.766 9.269 8.758 3.370 0.0307664 centromere protein T TUFM 9.230 9.309 6.760 11.062 10.282 10.506 3.371 0.0342527 Tu translation elongation factor, mitochondrial MTFMT 4.423 3.978 3.645 6.065 5.818 5.398 3.371 0.0213806 mitochondrial methionyl-tRNA formyltransferase PDHA1 7.666 7.561 7.553 9.642 9.317 8.925 3.379 0.0182014 pyruvate dehydrogenase (lipoamide) alpha 1 PRDM7 2.648 2.648 2.648 4.117 4.405 4.579 3.379 0.0142028 PR domain containing 7 C13orf34 2.648 3.295 4.108 5.341 4.405 5.210 3.379 0.0424385 chromosome 13 open reading frame 34 HSF1 8.871 8.403 9.661 10.626 11.419 10.339 3.380 0.0291359 heat shock transcription factor 1 SLC25A38 7.283 7.034 6.017 8.761 9.041 8.578 3.382 0.0177605 solute carrier family 25, member 38 FHL3 8.705 6.318 8.055 9.429 9.929 9.815 3.385 0.0333418 four and a half LIM domains 3 ZNF525 4.969 4.649 4.731 6.297 7.105 6.491 3.385 0.0161016 zinc finger protein 525 PPP1R13L 7.340 8.010 8.594 9.104 10.989 9.640 3.397 0.0348676 protein phosphatase 1, regulatory (inhibitor) subunit 13 like EIF4G3 4.539 5.355 5.114 6.607 6.822 7.120 3.399 0.0170437 eukaryotic translation initiation factor 4 gamma, 3 CCDC55 7.629 7.867 7.910 9.395 9.512 9.898 3.401 0.0138693 coiled-coil domain containing 55 TRAF7 9.545 8.051 8.191 10.726 10.620 9.817 3.402 0.0349896 TNF receptor-associated factor 7 C3orf62 5.504 4.517 5.174 6.687 6.798 7.273 3.409 0.0196121 chromosome 3 open reading frame 62 MAN1A1 6.851 5.452 5.790 7.560 7.293 8.077 3.410 0.0411185 mannosidase, alpha, class 1A, member 1 PPP2CB 10.861 11.026 11.350 12.521 12.798 13.235 3.414 0.0179456 protein phosphatase 2. catalytic subunit, beta isozyme DTNBP1 5.503 3.308 5.978 7.277 7.101 7.488 3.420 0.0254291 dystrobrevin binding protein 1 SNORD100 3.422 4.117 4.657 5.196 6.443 5.770 3.421 0.0347386 small nucleolar RNA, C/D box 100 SLAMF7 2.233 2.233 2.800 4.575 3.043 4.481 3.422 0.0456925 SLAM family member 7 C16orf54 3.947 4.768 4.387 6.163 6.039 6.257 3.424 0.0172003 chromosome 16 open reading frame 54 ZNF516 5.826 5.691 6.345 7.988 6.850 8.121 3.425 0.0326603 zinc finger protein 516 TRIM26 8.490 7.671 8.689 9.953 10.269 10.425 3.432 0.0171733 tripartite motif-containing 26 PLAGL2 7.663 8.235 7.638 9.417 9.930 9.505 3.432 0.0178825 pleiomorphic adenoma gene-like 2 ADAMTS10 7.906 5.428 6.771 7.955 8.551 9.579 3.433 0.0445882 ADAM metallopeptidase with thrombospondin type 1 motif, 10 RBM5 6.817 7.716 8.711 9.496 9.398 10.383 3.434 0.0285494 RNA binding motif protein 5 C6orf136 5.173 5.072 5.636 7.143 6.951 6.955 3.437 0.0162312 chromosome 6 open reading frame 136 NR5A2 5.039 4.350 3.830 6.132 6.134 6.462 3.445 0.0217251 nuclear receptor subfamily 5, group A, member 2 FAM38A 7.395 8.234 9.086 9.482 10.019 10.200 3.446 0.0421390 family with sequence similarity 38, member A MLH1 4.423 2.894 2.744 6.064 4.529 5.398 3.448 0.0341508 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)) ALDOC 5.039 5.444 5.241 6.852 7.027 7.203 3.449 0.0133237 aldolase C, fructose-bisphosphate HPS6 5.042 5.110 4.852 7.653 6.830 6.333 3.452 0.0193092 Hermansky-Pudlak syndrome 6 GLO1 10.704 9.282 9.793 12.492 12.161 10.917 3.453 0.0324308 glyoxalase I WDR4 5.482 5.085 4.810 5.892 7.020 7.271 3.455 0.0407622 WD repeat domain 4 HNRNPH3 9.245 8.732 9.176 10.965 9.828 12.149 3.455 0.0361244 heterogeneous nuclear ribonucleoprotein H3 (2H9) ANXA5 7.231 8.086 8.103 9.893 9.470 9.551 3.458 0.0191172 annexin A5 CCDC41 2.970 3.923 3.901 4.999 5.759 4.763 3.464 0.0399560 coiled-coil domain containing 41 MYNN 5.768 5.481 5.786 7.806 7.244 7.561 3.465 0.0129355 myoneurin FGF17 1.648 3.059 3.423 3.830 4.421 5.220 3.474 0.0450998 fibroblast growth factor 17 LOC100133991 3.422 3.059 2.281 4.376 4.529 5.220 3.477 0.0265300 No description SPHK1 9.575 9.692 10.659 11.321 12.458 12.269 3.480 0.0207726 sphingosine kinase 1 OGFOD2 5.109 4.388 5.818 7.180 6.908 6.290 3.480 0.0363816 2-oxoglutarate and iron-dependent oxygenase domain containing 2 WIPI1 4.482 4.924 5.726 7.175 6.516 6.723 3.481 0.0270166 WD repeat domain, phosphoinositide interacting 1 ZMIZ2 7.766 6.575 8.380 9.253 9.755 9.566 3.481 0.0265924 zinc finger, MIZ-type containing 2 UMPS 2.970 5.603 4.680 5.971 6.479 6.530 3.482 0.0452149 uridine monophosphate synthetase MAP3K7IP3 6.375 6.558 5.657 8.175 7.605 8.231 3.482 0.0213050 No description C12orf76 4.647 3.888 2.593 5.688 4.870 5.889 3.483 0.0455601 chromosome 12 open reading frame 76 TROVE2 7.583 7.527 8.072 9.384 9.384 9.618 3.485 0.0161383 TROVE domain family, member 2 SLC17A9 2.970 3.233 3.311 5.035 5.288 4.670 3.486 0.0144447 solute carrier family 17, member 9 CHST2 4.378 4.364 5.454 7.257 5.902 6.649 3.490 0.0291886 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 RASA2 2.233 2.233 2.288 4.033 4.037 4.669 3.491 0.0108475 RAS p21 protein activator 2 QPCTL 2.233 2.233 2.360 5.284 4.037 3.737 3.491 0.0187962 glutaminyl-peptide cyclotransferase-like ZNF737 5.378 4.697 5.415 6.583 7.027 7.219 3.493 0.0201071 zinc finger protein 737 MYST3 9.086 7.969 9.030 10.246 10.510 10.890 3.494 0.0233972 MYST histone acetyltransferase (monocytic leukemia) 3 ZNF589 4.972 3.256 4.602 6.031 5.246 6.777 3.495 0.0489029 zinc finger protein 589 ABCF1 7.460 7.458 8.469 9.764 10.021 9.264 3.497 0.0217549 ATP-binding cassette, sub-family F (GCN20), member 1 SRGAP1 8.241 9.046 8.545 9.639 10.458 10.854 3.501 0.0306776 SLIT-ROBO Rho GTPase activating protein 1 HADHA 9.696 8.511 8.838 10.790 10.774 10.319 3.502 0.0332205 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit C19orf6 9.917 8.300 10.602 11.725 11.784 11.549 3.503 0.0286562 chromosome 19 open reading frame 6 C17orf69 2.648 2.648 2.648 4.326 4.515 4.458 3.505 0.0094527 chromosome 17 open reading frame 69 COMMD2 3.860 1.962 2.359 4.972 4.870 3.773 3.508 0.0443484 COMM domain containing 2 NDUFA3 8.313 6.758 7.297 10.124 9.655 8.096 3.509 0.0482887 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9 kDa TRIM16 9.136 8.111 9.777 10.807 11.139 10.947 3.509 0.0239719 tripartite motif-containing 16 FAM178A 4.619 4.688 4.796 6.587 5.909 6.609 3.513 0.0210180 family with sequence similarity 178, member A CUL9 6.198 4.283 5.578 6.983 7.239 8.012 3.516 0.0271858 cullin 9 CWF19L1 4.977 4.238 4.051 6.792 6.300 5.741 3.517 0.0236378 CWF19-like 1, cell cycle control (S. pombe) SFRS16 6.177 5.362 7.018 8.054 7.991 7.557 3.518 0.0377501 No description ADPRHL1 3.233 3.233 3.247 5.049 4.490 5.118 3.519 0.0195733 ADP-ribosylhydrolase like 1 CREB3 6.967 7.139 7.928 9.516 9.396 8.782 3.521 0.0200496 cAMP responsive element binding protein 3 ZNF765 5.598 5.409 5.903 7.414 8.424 7.039 3.521 0.0198409 zinc finger protein 765 UBTF 8.561 7.021 7.495 8.902 9.313 9.425 3.526 0.0491400 upstream binding transcription factor, RNA polymerase I CCDC93 3.970 4.862 4.989 6.378 6.680 6.686 3.526 0.0158416 coiled-coil domain containing 93 NTN5 1.648 1.648 2.675 3.557 3.247 4.493 3.528 0.0323081 netrin 5 ESRP2 3.456 4.240 5.023 5.274 8.190 5.971 3.528 0.0386575 epithelial splicing regulatory protein 2 N4BP1 5.855 5.231 5.341 7.677 7.601 6.847 3.535 0.0175116 NEDD4 binding protein 1 MS4A7 5.235 5.146 5.927 7.374 6.969 7.176 3.537 0.0203088 membrane-spanning 4-domains, subfamily A, member 7 MUDENG 3.792 4.414 3.533 6.088 5.615 5.557 3.538 0.0185889 MU-2/AP1 M2 domain containing, death-inducing NFYA 8.520 7.105 7.581 9.407 9.030 9.662 3.547 0.0374243 nuclear transcription factor Y. alpha MRPS7 7.722 6.544 7.153 9.343 9.352 8.374 3.556 0.0251692 mitochondrial ribosomal protein S7 OPLAH 6.798 5.400 6.775 8.630 8.576 8.264 3.562 0.0164045 5-oxoprolinase (ATP-hydrolysing) NPM3 8.502 6.752 7.465 9.298 9.807 8.987 3.563 0.0354922 nucleophosmin/nucleoplasmin 3 GDAP2 5.604 4.333 4.868 6.701 6.943 6.528 3.565 0.0245057 ganglioside induced differentiation associated protein 2 ADRA2C 6.770 6.505 6.561 11.073 8.396 7.604 3.568 0.0340752 adrenergic, alpha-2C-, receptor FAM185A 2.233 2.233 2.233 3.278 4.624 4.071 3.573 0.0257737 family with sequence similarity 185, member A INO80 6.765 6.254 7.094 8.932 8.269 8.458 3.574 0.0184932 INO80 homolog (S. cerevisiae) SLC5A5 5.142 6.012 6.396 7.372 7.185 8.235 3.577 0.0329653 solute carrier family 5 (sodium iodide symporter), member 5 PAK1 4.378 5.858 6.068 7.027 7.697 7.850 3.578 0.0238603 p21 protein (Cdc42/Rac)-activated kinase 1 PBX3 5.293 4.817 3.398 5.424 6.657 6.870 3.580 0.0468121 pre-B-cell leukemia homeobox 3 DDX19A 1.648 2.234 2.177 4.017 3.353 4.376 3.580 0.0188052 DEAD (Asp-Glu-Ala-As) box polypeptide 19A PSKH1 2.970 4.917 4.407 6.180 6.251 6.409 3.590 0.0206312 protein serine kinase H1 ATR 4.793 3.945 4.947 6.712 6.791 5.598 3.590 0.0300114 ataxia telangiectasia and Rad3 related LOC440944 5.532 5.992 6.367 7.799 7.836 8.135 3.590 0.0135185 No description C16orf67 0.648 4.235 3.511 5.355 5.777 4.262 3.591 0.0456482 No description HTATSF1 3.233 4.070 4.081 5.671 5.768 5.927 3.594 0.0137328 HIV-1 Tat specific factor 1 TMEM43 8.660 7.806 8.399 10.118 10.571 9.652 3.595 0.0221334 transmembrane protein 43 KIAA0467 4.948 4.744 5.274 7.121 6.694 6.625 3.597 0.0150562 KIAA0467 PATL1 8.707 7.758 7.582 10.319 9.304 10.554 3.597 0.0219802 protein associated with topoisomerase II homolog 1 (yeast) SCO1 6.196 5.644 4.916 7.492 7.523 6.811 3.601 0.0322243 SCO cytochrome oxidase deficient homolog 1 (yeast) FAM100A 6.808 7.534 8.615 8.790 9.383 9.956 3.602 0.0450839 family with sequence similarity 100, member A DFFA 4.977 5.044 5.454 6.893 7.479 6.013 3.603 0.0367165 DNA fragmentation factor, 45 kDa, alpha polypeptide ATP5S 1.648 2.304 3.557 4.154 4.017 4.376 3.606 0.0437584 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) RIC8B 6.095 5.498 6.029 7.349 7.421 8.277 3.606 0.0220475 resistance to inhibitors of cholinesterase 8 homolog B (C. elegans) SPG7 8.184 7.046 7.635 9.248 9.454 10.035 3.606 0.0191927 spastic paraplegia 7 (pure and complicated autosomal recessive) ZNF544 4.580 4.448 5.104 6.624 6.954 5.766 3.607 0.0277924 zinc finger protein 544 PAOX 1.648 1.648 1.648 4.154 3.499 3.294 3.607 0.0123518 polyamine oxidase (exo-N4-amino) PNCK 1.648 1.648 1.648 3.023 3.499 5.082 3.607 0.0210631 pregnancy up-regulated non-ubiquitously expressed CaM kinase ZNF484 1.648 1.648 1.648 4.017 3.499 2.752 3.607 0.0241334 zinc finger protein 484 CLEC17A 1.648 3.023 1.648 3.830 3.499 4.692 3.607 0.0305813 C-type lectin domain family 17, member A SLC22A23 7.280 6.052 6.626 9.409 7.903 8.013 3.607 0.0383289 solute carrier family 22, member 23 DOM3Z 5.644 5.437 6.457 7.776 7.495 7.288 3.607 0.0267657 dom-3 homolog Z (C. elegans) ENDOG 6.829 6.040 6.433 8.422 8.564 7.891 3.608 0.0177868 endonuclease G CNBP 9.202 8.133 8.146 10.080 9.987 10.620 3.615 0.0278083 CCHC-type zinc finger, nucleic acid binding protein KPNB1 8.923 8.926 9.242 10.572 11.106 10.785 3.628 0.0145806 karyopherin (importin) beta 1 ZNF77 3.194 3.336 1.387 5.035 5.196 4.748 3.629 0.0179678 zinc finger protein 77 DNER 3.233 4.409 5.347 6.891 6.271 6.172 3.636 0.0255303 delta/notch-like EGF repeat containing PSENEN 7.650 7.645 7.258 9.737 9.510 8.691 3.641 0.0219983 presenilin enhancer 2 homolog (C. elegans) ZGLP1 3.422 1.834 2.309 3.714 4.174 4.773 3.643 0.0416655 zinc finger, GATA-like protein 1 FLJ42627 4.958 4.783 5.389 6.648 6.848 6.940 3.644 0.0155705 No description USP13 6.288 6.295 6.284 8.161 8.419 8.068 3.663 0.0083872 ubiquitin specific peptidase 13 (isopeptidase T-3) ILK 10.084 7.862 9.432 11.306 11.285 11.425 3.665 0.0230922 integrin-linked kinase GGNBP2 7.800 7.536 8.512 9.410 9.703 10.139 3.665 0.0228489 gametogenetin binding protein 2 IFI30 5.109 6.479 5.819 6.983 7.319 8.933 3.665 0.0375393 interferon, gamma-inducible protein 30 TUBGCP5 5.404 4.127 4.564 6.986 6.005 6.866 3.676 0.0245979 tubulin, gamma complex associated protein 5 PCNT 6.619 5.234 7.288 8.497 8.166 8.742 3.678 0.0253591 pericentrin TCEB3 7.839 8.338 8.535 9.689 10.639 10.217 3.678 0.0169050 transcription elongation factor B (SIH), polypeptide 3 (110 kDa, elong in A) ZDHHC14 7.452 7.148 6.871 8.750 9.326 9.094 3.679 0.0138873 zinc finger, DHHC-type containing 14 USP32 2.648 3.104 3.016 4.182 4.899 5.549 3.687 0.0200315 ubiquitin specific peptidase 32 MLEC 9.687 8.317 8.346 10.419 10.199 10.893 3.688 0.0349542 malectin PARP8 4.264 4.719 4.264 6.268 6.151 6.479 3.697 0.0119671 poly (ADP-ribose) polymerase family, member 8 PLODS 8.185 7.007 7.564 9.452 9.577 8.923 3.702 0.0272281 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 PHF1 9.216 8.642 9.686 11.106 9.932 11.665 3.705 0.0428454 PHD finger protein 1 DHRS12 5.552 3.685 4.647 6.539 6.103 7.255 3.712 0.0291005 dehydrogenase/reductase (SDR family) member 12 ARHGAP27 5.619 4.281 6.536 7.512 7.959 7.218 3.713 0.0286423 Rho GTPase activating protein 27 ZC3H8 2.233 3.975 2.587 4.481 5.183 4.481 3.716 0.0372724 zinc finger CCCH-type containing 8 RHEBL1 3.619 5.075 2.814 5.256 5.513 6.290 3.718 0.0445473 Ras homolog enriched in brain like 1 OTUD4 9.996 9.664 9.698 10.719 11.593 11.999 3.719 0.0312731 OTU domain containing 4 CHEK1 4.936 3.983 4.676 6.050 6.831 6.290 3.721 0.0209002 CHK1 checkpoint homolog (S. pombe) ABH 7.988 8.356 8.720 9.886 10.518 10.341 3.725 0.0157785 abl-interactor 1 ECD 7.367 7.160 8.083 9.094 9.266 9.340 3.731 0.0230250 ecdysoneless homolog (Drosophila) GABBR1 7.671 7.107 7.957 9.565 9.296 9.857 3.733 0.0139865 gamma-aminobutyric acid (GABA) B receptor, 1 UBA5 6.950 6.261 6.305 8.850 8.364 7.802 3.734 0.0223775 ubiquitin-like modifier activating enzyme 5 RA114 8.591 6.621 7.056 9.601 9.930 8.524 3.739 0.0393362 retinoic acid induced 14 SGIP1 4.422 4.359 3.218 6.291 5.562 6.264 3.746 0.0191546 SH3-domain GRB2-like (endophilin) interacting protein 1 HES6 6.262 3.983 5.109 7.514 6.785 7.016 3.750 0.0333154 hairy and enhancer of split 6 (Drosophila) ZC3H3 6.838 5.934 7.399 8.746 8.963 8.198 3.752 0.0248114 zinc finger CCCH-type containing 3 ASAP3 4.709 2.970 3.178 5.854 4.707 6.617 3.754 0.0326416 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 ARPM1 1.648 1.648 1.689 3.557 4.174 3.557 3.754 0.0086423 No description FRG2 1.648 1.834 1.648 3.830 3.247 3.557 3.754 0.0130776 FSHD region gene 2 GNAL 1.648 1.648 1.834 3.557 3.499 5.512 3.754 0.0159816 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type OR52R1 1.648 1.648 2.304 4.376 3.499 3.557 3.754 0.0175816 olfactory receptor, family 52, subfamily R, member 1 SLC6A7 1.648 1.648 1.834 3.023 4.017 3.557 3.754 0.0183470 solute carrier family 6 (neurotransmitter transporter, L- proline), member 7 TMED10P 1.648 1.648 1.648 3.830 2.739 3.557 3.754 0.0239581 No description BAIAP2 7.982 8.407 9.175 9.586 10.503 11.084 3.755 0.0307324 BAH-associated protein 2 C12orf48 2.648 2.970 3.897 4.883 5.244 4.579 3.764 0.0290915 chromosome 12 open reading frame 48 PRELID1 6.418 6.578 6.689 8.490 8.717 7.712 3.764 0.0225099 PRELI domain containing 1 MMP12 4.895 9.347 9.598 11.512 10.387 10.215 3.767 0.0464198 matrix metallopeptidase 12 (macrophage elastase) UBL4A 7.580 4.117 6.196 8.964 8.110 7.882 3.769 0.0369341 ubiquitin-like 4A GUF1 4.793 4.985 3.666 6.708 6.720 5.927 3.772 0.0231102 GUF1 GTPase homolog (S. cerevisiae) PRDX3 8.909 7.208 7.900 11.046 9.816 9.021 3.773 0.0404052 peroxiredoxin 3 SMUG1 4.423 4.325 4.477 6.340 6.443 5.997 3.777 0.0111927 single-strand-selective monofunctional uracil-DNA glycosylase 1 CD300C 2.233 2.233 3.029 4.151 3.467 5.147 3.777 0.0370153 CD300c molecule TNIK 2.233 2.951 3.966 4.151 4.889 5.147 3.777 0.0452288 TRAF2 and NCK interacting kinase GTF2B 7.019 7.027 8.056 8.998 8.939 9.267 3.784 0.0265057 general transcription factor I IB RAVER2 4.264 2.648 2.937 4.797 5.977 4.857 3.784 0.0322153 ribonucleoprotein, PTB-binding 2 NBEAL2 6.118 5.382 6.684 7.165 8.220 8.605 3.785 0.0285882 neurobeachin-like 2 FRG1 5.042 5.652 4.339 7.303 7.162 6.261 3.789 0.0261071 FSHD region gene 1 TTL 6.610 5.212 6.470 8.464 8.393 8.263 3.792 0.0131685 tubulin tyrosine ligase PPIL5 3.422 4.008 3.814 5.908 5.932 4.493 3.795 0.0371040 peptidylprolyl isomerase (cyclophilin)-like 5 DPP9 8.259 7.071 8.201 10.587 10.044 8.995 3.796 0.0263920 dipeptidyl-peptidase 9 SRRM3 1.648 2.450 4.008 4.376 4.174 5.459 3.800 0.0418887 serine/arginine repetitive matrix 3 CCDC149 3.233 3.983 4.391 5.315 5.359 6.322 3.813 0.0290672 coiled-coil domain containing 149 SEC16A 7.844 7.377 8.606 9.779 10.096 9.406 3.824 0.0245619 SEC16 homolog A (S. cerevisiae) NHEDC2 7.020 5.031 5.625 7.958 7.560 7.533 3.824 0.0385640 Na+/H+ exchanger domain containing 2 RNASEH1 6.444 4.667 4.799 8.253 6.851 6.603 3.825 0.0419289 ribonuclease H1 C1orf163 2.233 4.263 4.677 6.199 6.428 5.793 3.828 0.0218215 chromosome 1 open reading frame 163 DIO3 3.422 1.648 2.234 4.017 4.174 5.289 3.838 0.0279934 deiodinase, iodothyronine, type III ALKBH6 4.817 3.956 3.569 6.161 6.205 5.509 3.840 0.0247158 alkB, alkylation repair homolog 6 (E. coli)) CUL4A 7.781 7.426 8.913 9.370 9.900 9.951 3.849 0.0354104 cullin 4A TRABD 7.434 7.857 7.690 9.500 9.636 9.656 3.853 0.0091317 TraB domain containing MDH1 8.010 7.886 7.762 10.077 9.832 9.489 3.853 0.0114326 malate dehydrogenase 1, NAD (soluble) POMT2 6.198 6.193 6.556 8.543 8.148 7.438 3.863 0.0246672 protein-O-mannosyltransferase 2 PIGS 7.666 6.186 6.437 9.247 8.388 8.275 3.867 0.0301009 phosphatidylinositol glycan anchor biosynthesis, class S IL17RA 5.580 5.495 5.861 7.778 7.769 7.449 3.873 0.0083601 interleukin 17 receptor A NUDT22 4.142 4.473 3.718 7.165 6.096 4.669 3.874 0.0453563 nudix (nucleoside diphosphate linked moiety X)-type motif 22 AKT1 9.221 8.268 9.283 11.238 10.720 10.638 3.876 0.0185660 v-akt murine thymoma viral oncogene homolog 1 CCDC57 5.861 5.370 6.207 7.488 8.164 7.482 3.881 0.0177147 coiled-coil domain containing 57 FOXC2 4.525 4.253 5.786 7.433 7.662 6.211 3.883 0.0215213 forkhead box C2 (MFH-1, mesenchyme forkhead 1) TPRKB 6.001 5.770 6.505 8.505 7.959 7.209 3.885 0.0265646 TP53RK binding protein INCENP 4.264 3.251 3.475 5.266 5.896 5.434 3.886 0.0200891 inner centromere protein antigens 135/155 kDa TBP 5.293 5.118 5.997 7.859 7.742 7.078 3.891 0.0140974 TATA box binding protein TRPV1 2.233 2.814 3.170 4.151 5.183 4.777 3.899 0.0190950 transient receptor potential cation channel, subfamily V, member 1 GTF2I 0.648 1.078 2.401 2.714 3.633 3.043 3.906 0.0401931 general transcription factor Hi GOLGB1 7.032 7.120 7.600 9.566 8.527 9.556 3.907 0.0182159 golgin B1 YTHDC1 9.741 8.974 9.799 11.351 10.942 11.947 3.914 0.0204364 YTH domain containing 1 SFRS13B 2.648 2.648 2.999 4.981 4.618 4.579 3.916 0.0102679 No description ATP6VOA1 7.355 6.503 8.334 9.326 8.549 9.571 3.921 0.0421244 ATPase, H+ transporting, lysosomal VO subunit a1 ARPC3 2.233 2.917 3.078 5.773 4.889 3.737 3.923 0.0272773 actin related protein 2/3 complex, subunit 3, 21 kDa LOC284578 3.422 3.645 3.638 7.142 5.304 5.610 3.924 0.0138270 No description SLC29A1 9.394 7.542 8.666 10.639 10.978 10.140 3.928 0.0249750 solute carrier family 29 (nucleoside transporters), member 1 CEP57 6.314 5.009 5.478 7.452 7.121 7.657 3.928 0.0250021 centrosomal protein 57 kDa NCRNA00085 4.008 2.744 2.177 4.154 5.120 5.289 3.937 0.0361494 non-protein coding RNA 85 HSPBP1 7.039 6.537 6.451 10.072 8.374 8.514 3.937 0.0165466 HSPA (heat shock 70 kDa) binding protein, cytoplasmic cochaperone 1 TNKS2 6.595 6.655 6.694 7.562 8.744 8.632 3.937 0.0295629 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 MCF2L 5.751 4.639 4.616 7.724 6.683 6.594 3.938 0.0238423 MCF.2 cell line derived transforming sequence-like CCDC154 1.648 3.420 4.008 5.459 4.529 5.398 3.939 0.0321640 coiled-coil domain containing 154 NICN1 5.171 3.842 4.455 6.135 6.433 6.856 3.940 0.0199095 nicolin 1 POU3F1 4.482 3.716 4.463 5.695 6.271 7.991 3.943 0.0195047 POU class 3 homeobox 1 ARHGAP11A 2.648 3.579 3.090 5.558 4.915 4.755 3.943 0.0170049 Rho GTPase activating protein 11A RBAK 3.233 4.348 4.652 5.799 5.213 6.763 3.943 0.0364503 RB-associated KRAB zinc finger MBOAT2 6.333 5.615 5.343 7.595 7.659 7.500 3.943 0.0186250 membrane bound O-acyltransferase domain containing 2 CDK16 9.995 8.357 9.617 11.598 11.697 11.495 3.949 0.0149369 cyclin-dependent kinase 16 LOC284232 7.790 7.097 7.385 9.292 9.366 9.757 3.949 0.0109584 No description FLU 7.734 8.450 5.995 9.861 9.716 8.475 3.950 0.0462555 flightless I homolog (Drosophila) HAUS5 6.264 4.557 5.579 7.449 7.613 7.561 3.950 0.0199317 HAUS augmin-like complex, subunit 5 MOCS3 4.142 3.549 3.834 5.845 5.513 6.124 3.952 0.0121924 molybdenum cofactor synthesis 3 MBD4 8.343 7.706 8.086 10.075 10.031 10.069 3.952 0.0095553 methyl-CpG binding domain protein 4 C15orf17 7.166 6.541 6.604 8.523 9.123 8.851 3.953 0.0111657 chromosome 15 open reading frame 17 DAZAP2 10.824 10.127 10.325 13.205 12.225 12.111 3.958 0.0156315 DAZ associated protein 2 H2AFZ 10.786 10.269 11.701 12.252 13.079 13.686 3.958 0.0239920 H2A histone family, member Z RAB4B 3.422 2.926 2.721 5.409 5.304 4.376 3.966 0.0170589 RAB4B, member RAS oncogene family POLN 0.648 0.648 0.999 2.714 2.987 2.370 3.966 0.0122839 polymerase (DNA directed) nu RNMTL1 5.600 5.937 5.018 7.925 7.492 7.462 3.969 0.0117633 RNA methyltransferase like 1 LRRC56 4.793 3.314 3.476 5.305 5.308 6.870 3.974 0.0350236 leucine rich repeat containing 56 ABCC13 4.817 4.153 4.083 6.168 6.074 6.234 3.976 0.0161931 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene HSPBAP1 2.233 4.309 5.738 6.474 6.301 5.973 3.977 0.0460073 HSPB (heat shock 27 kDa) associated protein 1 TM2D2 5.849 5.224 5.898 8.110 7.670 7.216 3.979 0.0151504 TM2 domain containing 2 ZNF876P 0.648 0.648 2.268 4.262 2.987 2.370 3.984 0.0370243 zinc finger protein 876, pseudogene ERCC8 2.233 2.233 2.524 3.981 4.624 4.230 3.991 0.0116620 excision repair cross-complementing rodent repair deficiency, complementation group 8 ZNF414 2.233 3.956 3.508 6.336 5.017 4.230 3.991 0.0424724 zinc finger protein 414 MPHOSPH10 6.689 6.948 7.410 9.326 9.357 8.686 3.993 0.0116530 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) NXPH4 3.194 1.649 3.043 4.262 5.196 3.966 4.005 0.0359920 neurexophilin 4 KIAA2018 7.596 6.373 5.048 8.755 8.071 8.377 4.010 0.0338541 KIAA2018 MAD2L1BP 5.690 4.094 5.822 8.067 6.099 7.403 4.012 0.0407380 MAD2L1 binding protein RAB11FIP5 5.378 5.139 5.219 7.225 6.676 7.485 4.016 0.0147532 RAB11 family interacting protein 5 (class l) KDM6B 11.701 11.274 12.262 12.943 13.707 14.828 4.017 0.0251997 lysine (K)-specific demethylase 6B UBE4B 8.578 7.394 8.328 10.155 10.585 10.310 4.020 0.0114735 ubiquitination factor E4B (UFD2 homolog, yeast) AP2S1 9.645 7.544 8.317 11.652 10.446 9.420 4.021 0.0459893 adaptor-related protein complex 2, sigma 1 subunit PLLP 0.648 1.387 3.046 4.262 5.053 2.370 4.021 0.0457016 plasmolipin TIPIN 4.008 2.625 3.296 5.420 5.304 5.082 4.022 0.0195137 TIMELESS interacting protein CCDC146 2.648 3.104 4.009 5.435 4.857 5.112 4.022 0.0236773 coiled-coil domain containing 146 DCTN2 9.466 8.661 9.027 11.476 11.099 10.317 4.028 0.0212690 dynactin 2 (p50) FIBP 6.985 5.596 7.327 9.337 8.899 8.672 4.029 0.0157605 fibroblast growth factor (acidic) intracellular binding protein ZC3H12B 2.648 2.970 3.013 4.981 4.273 5.945 4.029 0.0166825 zinc finger CCCH-type containing 12B HSF4 4.142 2.702 4.165 4.713 5.858 7.213 4.031 0.0309071 heat shock transcription factor 4 PPEF2 0.648 3.351 1.649 3.662 3.633 4.389 4.035 0.0409113 protein phosphatase, EF-hand calcium binding domain 2 RASA4P 7.133 5.349 6.308 8.065 7.613 9.148 4.042 0.0317043 No description ATP6VOC 11.392 11.124 12.116 13.139 13.542 13.505 4.043 0.0188302 ATPase, H+ transporting, lysosomal 16 kDa, VO subunit c APOL1 2.233 2.391 2.261 4.276 4.151 4.590 4.043 0.0075269 apolipoprotein L, 1 NCRNA00169 1.648 2.450 3.140 4.400 4.469 5.122 4.053 0.0150922 non-protein coding RNA 169 ZNF814 3.456 3.607 4.072 5.627 6.183 5.074 4.055 0.0189529 zinc finger protein 814 ZNF496 5.993 4.661 5.278 7.299 7.168 7.506 4.057 0.0172780 zinc finger protein 496 SLMAP 4.672 5.517 6.512 7.648 7.538 7.154 4.058 0.0298957 sarcolemma associated protein RC3H2 4.793 6.098 6.583 8.120 7.755 8.308 4.061 0.0178256 ring finger and CCCH-type domains 2 PDLIM4 10.265 9.871 10.827 11.986 13.230 11.894 4.064 0.0214555 PDZ and LIM domain 4 ZNF70 1.648 3.247 2.601 4.624 5.060 4.376 4.065 0.0169861 zinc finger protein 70 BCKDK 8.242 7.557 8.335 10.857 10.056 9.581 4.069 0.0163893 branched chain ketoacid dehydrogenase kinase ZXDC 7.569 6.806 7.344 9.595 8.936 8.923 4.073 0.0166596 ZXD family zinc finger C EIF2B5 6.735 6.855 8.332 9.285 9.767 8.763 4.078 0.0283338 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82 kDa PPARD 8.702 6.253 8.222 9.963 10.730 10.219 4.079 0.0176905 peroxisome proliferator-activated receptor delta CEP250 5.431 3.861 4.079 7.160 5.889 6.724 4.080 0.0236288 centrosomal protein 250 kDa EDNRB 11.826 11.306 11.616 14.958 13.335 13.629 4.082 0.0133147 endothelin receptor type B DENND1A 7.605 5.415 6.636 9.635 8.411 8.180 4.086 0.0289667 DENN/MADD domain containing 1A PPP2R5B 7.555 6.194 6.454 9.066 8.883 8.226 4.090 0.0224343 protein phosphatase 2, regulatory subunit B′, beta MAP4K4 8.636 9.286 9.673 11.296 11.196 11.705 4.090 0.0111116 mitogen-activated protein kinase kinase kinase kinase 4 SLC25A22 4.378 3.500 4.115 6.101 6.410 5.889 4.090 0.0110284 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 ABHD3 2.233 4.928 3.529 4.871 5.561 6.655 4.091 0.0412101 abhydrolase domain containing 3 DGKA 6.340 3.544 5.648 7.529 7.681 8.063 4.092 0.0202936 diacylglycerol kinase, alpha 80 kDa ZNF563 4.008 2.121 2.177 4.154 4.421 5.398 4.092 0.0414686 zinc finger protein 563 CHMP4A 6.262 4.858 6.008 8.295 7.505 7.566 4.093 0.0198769 chromatin modifying protein 4A ABCD1 5.899 5.391 5.855 7.534 7.425 8.257 4.094 0.0136898 ATP-binding cassette, sub-family D (ALD), member 1 PARG 4.524 4.744 4.192 6.560 5.643 6.780 4.101 0.0225286 poly (ADP-ribose) glycohydrolase AP4S1 7.503 7.841 7.510 8.986 9.546 10.537 4.102 0.0186159 adaptor-related protein complex4, sigma 1 subunit C4orf42 3.947 3.621 4.761 5.966 5.985 6.188 4.107 0.0172627 chromosome 4 open reading frame 42 ALG12 5.936 5.181 5.658 8.266 7.696 6.640 4.109 0.0255893 asparagine-linked glycosylation 12, alpha-1,6- mannosyltransferase homolog (S. cerevisiae) UBE3C 8.173 7.536 8.052 10.092 10.405 9.272 4.112 0.0172939 ubiquitin protein ligase E3C SRGAP2 6.994 6.284 7.097 9.034 8.239 9.778 4.114 0.0163158 SLIT-ROBO Rho GTPase activating protein 2 CCDC24 4.008 2.304 2.776 5.459 6.049 4.104 4.115 0.0290825 coiled-coil domain containing 24 SNHG10 2.233 4.336 4.206 5.968 5.017 6.378 4.119 0.0293813 small nucleolar RNA host gene 10 (non-protein coding) FOXP3 2.233 2.233 2.233 4.276 4.697 4.230 4.120 0.0060205 forkhead box P3 GPC2 2.233 2.233 2.233 4.276 4.413 4.071 4.120 0.0067574 glypican 2 DGCR11 1.648 2.450 3.077 4.830 3.805 4.493 4.122 0.0238513 DiGeorge syndrome critical region gene 11 BNIP2 6.224 6.031 6.154 8.267 8.256 7.923 4.122 0.0076350 BCL2/adenovirus E1B 19 kDa interacting protein 2 PDPK1 6.813 6.039 5.861 8.178 7.905 8.437 4.122 0.0165376 3-phosphoinositide dependent protein kinase-1 SLC7A5P2 2.648 4.520 4.953 6.404 6.329 6.998 4.127 0.0171525 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 2 TNRC18 8.849 6.191 7.251 10.000 8.815 9.296 4.127 0.0472641 trinucleotide repeat containing 18 CCDC71 6.001 4.767 5.748 8.029 7.796 7.196 4.136 0.0154950 coiled-coil domain containing 71 KPNA5 2.648 3.567 3.894 4.981 5.414 5.945 4.142 0.0183990 karyopherin alpha 5 (importin alpha 6) TRMT61B 4.142 4.142 2.628 5.905 6.192 5.738 4.142 0.0149972 tRNA methyltransferase 61 homolog B (S. cerevisiae) EPS8L1 4.142 2.951 2.814 5.003 7.330 4.230 4.145 0.0420884 EPS8-like 1 CENPM 1.648 2.675 2.894 3.830 4.945 3.929 4.145 0.0305903 centromere protein M FGFR3 5.322 4.381 5.248 5.845 7.300 8.893 4.146 0.0298076 fibroblast growth factor receptor 3 ZNF397OS 4.264 3.747 4.788 6.317 6.211 6.838 4.147 0.0118929 No description C14orf105 1.648 1.834 1.648 3.888 3.704 2.752 4.151 0.0249147 chromosome 14 open reading frame 105 SDF4 10.338 8.703 9.394 11.862 11.449 10.800 4.153 0.0302035 stromal cell derived factor 4 RPL23AP82 1.648 1.648 1.648 3.557 3.704 3.929 4.158 0.0060863 ribosomal protein L23a pseudogene 82 ELP2P 1.648 1.648 2.064 2.625 3.704 4.607 4.158 0.0334853 No description MVK 4.936 4.624 5.907 7.711 7.215 6.681 4.160 0.0203380 mevalonate kinase CABLES1 5.204 3.797 3.902 6.164 5.855 6.554 4.165 0.0261841 Cdk5 and Abi enzyme substrate 1 MGC3771 1.648 1.648 1.648 3.707 3.353 3.942 4.166 0.0088510 No description RNF125 5.107 4.214 3.808 6.273 5.984 6.367 4.167 0.0238333 ring finger protein 125 KTELC1 6.677 5.416 5.666 8.373 7.894 7.476 4.169 0.0210451 No description HEATR2 4.793 3.661 3.233 5.293 5.768 5.768 4.170 0.0350326 HEAT repeat containing 2 GPT2 5.377 3.884 4.178 6.240 8.365 5.608 4.173 0.0355712 glutamic pyruvate transaminase (alanine aminotransferase) 2 WHSC1 6.167 6.513 5.893 8.229 8.397 8.167 4.173 0.0086603 Wolf-Hirschhorn syndrome candidate 1 OFD1 6.510 6.659 6.864 8.090 8.927 8.848 4.178 0.0147192 oral-facial-digital syndrome 1 FCHSD1 3.456 4.151 4.547 6.151 5.593 6.610 4.178 0.0173369 FCH and double SH3 domains 1 TTLL4 5.482 6.844 7.584 8.907 9.456 8.801 4.178 0.0167158 tubulin tyrosine ligase-like family, member 4 RHCG 2.970 4.686 3.859 6.437 5.034 6.188 4.181 0.0285029 Rh family, C glycoprotein TIMM17A 9.253 8.712 9.246 11.310 11.478 10.705 4.182 0.0116080 translocase of inner mitochondrial membrane 17 homolog A (yeast) CNPY3 8.151 6.105 8.124 10.215 9.877 9.134 4.182 0.0244724 canopy 3 homolog (zebrafish) C8orf33 7.167 7.627 7.817 9.882 9.621 9.678 4.185 0.0074014 chromosome 8 open reading frame 33 MAGEA1 0.648 0.648 0.648 2.714 2.987 2.370 4.187 0.0087400 melanoma antigen family A, 1 (directs expression of antigen MZ2-E) FKSG83 0.648 0.648 0.648 2.714 2.353 3.773 4.187 0.0120669 No description ASF1B 0.648 0.648 0.999 2.714 4.428 2.370 4.187 0.0169542 ASF1 anti-silencing function 1 homolog B (S. cerevisiae) FAM159A 0.648 0.648 0.999 2.714 2.353 5.407 4.187 0.0209182 family with sequence similarity 159, member A ZMYND10 0.648 0.648 1.719 2.714 2.353 4.262 4.187 0.0276579 zinc finger, MYND-type containing 10 HSD17B10 8.285 7.070 7.997 10.351 10.247 8.995 4.187 0.0232849 hydroxysteroid (17-beta) dehydrogenase 10 CRX 4.142 4.720 5.616 6.787 6.851 6.290 4.189 0.0275906 cone-rod homeobox C4orf14 7.661 4.975 6.259 8.292 8.941 8.330 4.202 0.0290028 chromosome 4 open reading frame 14 ZNF493 7.705 7.353 7.667 9.654 9.426 10.053 4.207 0.0082305 zinc finger protein 493 SEC31B 4.948 4.265 4.678 6.751 6.591 7.001 4.207 0.0085508 SEC31 homolog B (S. cerevisiae) UPF3B 6.070 5.010 5.777 7.850 8.032 7.836 4.208 0.0090756 UPF3 regulator of nonsense transcripts homolog B (yeast) EHMT2 7.498 4.420 5.933 8.998 7.833 8.006 4.209 0.0325737 euchromatic histone-lysine N-methyltransferase 2 PQLC1 9.647 8.598 9.636 10.672 11.309 12.088 4.211 0.0223068 PQ loop repeat containing 1 POLR2A 10.569 9.289 8.914 11.618 11.056 11.363 4.212 0.0350991 polymerase (RNA) II (DNA directed) polypeptide A, 220 kDa CSTF3 4.525 3.899 3.571 5.647 6.119 6.570 4.216 0.0145237 cleavage stimulation factor. 3′ pre-RNA. subunit 3. 77 kDa TMC8 4.194 2.121 3.435 3.909 5.511 7.191 4.217 0.0447331 transmembrane channel-like 8 GSS 6.859 4.667 6.268 8.740 8.345 7.630 4.217 0.0231858 glutathione synthetase SV2A 5.941 5.451 4.662 9.010 7.528 6.344 4.220 0.0295220 synaptic vesicle glycoprotein 2A PDDC1 4.233 5.060 5.102 6.674 6.807 7.180 4.223 0.0126173 Parkinson disease 7 domain containing 1 POLL 6.227 3.104 4.850 7.195 6.852 6.929 4.224 0.0327019 polymerase (DNA directed), lambda C8orf46 4.734 3.294 2.206 5.381 5.380 5.220 4.246 0.0403858 chromosome 8 open reading frame 46 KIAA0368 8.292 8.703 9.555 10.527 10.789 11.206 4.247 0.0189778 KIAA0368 HPX 1.648 2.744 3.880 4.830 4.174 5.220 4.248 0.0349092 hemopexin SLC27A5 5.452 2.926 5.384 6.847 7.539 6.261 4.248 0.0313958 solute carrier family 27 (fatty acid transporter), member 5 RANBP9 8.963 7.159 7.707 9.923 9.246 10.302 4.251 0.0341050 RAN binding protein 9 KRT80 4.672 5.700 6.593 6.761 8.885 7.456 4.254 0.0394839 keratin 80 WDR90 3.233 4.236 3.929 6.326 5.883 5.651 4.257 0.0124939 WD repeat domain 90 ZBTB39 3.648 4.300 4.484 6.625 5.977 5.739 4.258 0.0171913 zinc finger and BTB domain containing 39 COG1 6.444 4.784 5.551 8.388 7.647 7.618 4.274 0.0159158 component of oligomeric golgi complex 1 HLA-B 13.748 12.382 12.842 15.517 14.790 14.938 4.277 0.0176683 major histocompatibility complex, class I, B SCNN1D 5.008 3.218 4.104 5.314 6.612 7.019 4.278 0.0259345 sodium channel, nonvoltage-gated 1, delta CRTC2 5.619 6.693 7.222 8.790 8.528 9.291 4.278 0.0140094 CREB regulated transcription coactivator 2 MCM2 5.524 3.557 5.060 7.621 6.934 6.333 4.279 0.0237348 minichromosome maintenance complex component 2 ITK 3.860 3.046 1.564 3.662 4.870 7.329 4.281 0.0439359 IL2-inducible T-cell kinase TCIRG1 8.038 6.967 7.892 10.141 9.254 9.545 4.296 0.0184530 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal VO subunit A3 ORC2L 3.233 3.486 4.111 5.791 5.425 5.593 4.306 0.0134139 No description SMG6 8.387 5.654 7.342 9.452 9.410 9.808 4.316 0.0227102 Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) UBE2J1 9.057 8.400 8.348 11.387 10.511 10.397 4.319 0.0134846 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) ATP5J2 5.396 4.924 4.709 7.035 7.559 6.290 4.319 0.0202229 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 PNLDC1 4.314 2.941 3.284 5.739 5.053 5.889 4.325 0.0201868 poly(A)-specific ribonuclease (PARN)-like domain containing 1 VPS25 7.268 6.662 6.941 10.201 9.055 8.212 4.327 0.0208461 vacuolar protein sorting 25 homolog (S. cerevisiae) C15orf57 5.552 4.919 4.988 7.298 7.667 7.014 4.331 0.0095913 chromosome 15 open reading frame 57 MKLN1 7.895 7.414 8.140 9.529 9.935 10.438 4.331 0.0120343 muskelin 1, intracellular mediator containing kelch motifs CECR7 2.233 3.170 3.726 4.713 4.624 5.842 4.336 0.0258596 cat eye syndrome chromosome region, candidate 7 (non- protein coding) RAPGEFL1 5.600 3.802 4.715 7.659 6.949 5.919 4.338 0.0283678 Rap guanine nucleotide exchange factor (GEF)-like 1 MECR 4.709 4.977 5.498 7.389 7.281 6.828 4.344 0.0112177 mitochondrial trans-2-enoyl-CoA reductase LOC728606 2.648 4.379 4.301 5.800 6.071 6.499 4.345 0.0166277 No description CYP2B6 2.648 2.904 3.015 5.024 4.896 5.026 4.346 0.0057036 cytochrome P450, family 2. subfamily B. polypeptide 6 ZNF394 2.233 2.360 2.499 4.481 4.624 4.071 4.350 0.0091650 zinc finger protein 394 SHROOM2 2.233 2.360 2.903 4.481 5.126 4.071 4.350 0.0151324 shroom family member 2 PDE4D 5.926 6.705 6.239 8.594 7.887 8.826 4.350 0.0128953 phosphodiesterase 4D, cAMP-specific UNC45A 8.030 6.836 7.577 10.153 9.200 9.238 4.358 0.0192156 unc-45 homolog A (C. elegans) ZC3H6 7.434 7.466 8.566 9.669 9.846 9.560 4.364 0.0211920 zinc finger CCCH-type containing 6 PIGL 5.452 3.832 4.734 6.860 6.534 6.866 4.364 0.0189619 phosphatidylinositol glycan anchor biosynthesis, class L SH2B2 5.809 3.861 5.538 6.872 7.471 7.936 4.368 0.0194728 SH2B adaptor protein 2 BMS1P1 0.648 2.401 3.336 4.529 4.043 5.230 4.371 0.0236017 BMS1 pseudogene 1 PPP2R3B 4.657 2.768 4.667 5.892 6.262 6.796 4.375 0.0217161 protein phosphatase 2, regulatory subunit B″, beta KRTCAP3 3.422 3.209 1.978 4.109 5.730 4.493 4.381 0.0358672 keratinocyte associated protein 3 TPRG1L 8.413 7.366 8.117 10.548 9.810 9.702 4.391 0.0166367 tumor protein p63 regulated 1 -like SART1 8.073 7.520 8.416 10.211 10.449 9.758 4.400 0.0120759 squamous cell carcinoma antigen recognized by T cells VHL 7.937 7.208 8.090 10.228 9.758 9.925 4.400 0.0096274 von Hippel-Lindau tumor suppressor REV1 6.317 6.289 6.230 7.702 8.490 8.427 4.404 0.0138541 REV1 homolog (S. cerevisiae) WDR5 3.947 5.174 4.755 7.083 7.313 6.011 4.405 0.0186589 WD repeat domain 5 LOC283731 3.194 0.648 2.170 3.351 4.311 5.230 4.412 0.0319047 No description STK39 7.181 3.702 6.072 8.215 9.060 8.022 4.415 0.0233376 serine threonine kinase 39 C14orf182 3.619 2.233 2.233 4.378 5.561 4.669 4.423 0.0206964 chromosome 14 open reading frame 182 ALG3 7.922 6.975 7.220 10.068 9.895 8.802 4.427 0.0157286 asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae) ARF1 12.826 12.100 12.895 15.110 14.522 14.247 4.429 0.0155795 ADP-ribosylation factor 1 KLB 2.233 2.870 3.687 3.737 5.017 6.511 4.430 0.0376433 klotho beta C2orf60 5.142 4.009 3.940 6.749 6.089 6.335 4.434 0.0185071 chromosome 2 open reading frame 60 NCS1 9.287 8.828 9.232 11.077 11.436 11.160 4.436 0.0077792 neuronal calcium sensor 1 PNPLA2 9.021 7.968 8.369 10.241 10.902 10.522 4.447 0.0138964 patatin-like phospholipase domain containing 2 NCBP1 4.904 3.776 4.032 5.587 7.059 6.446 4.454 0.0205016 nuclear cap binding protein subunit 1,80 kDa REC8 4.817 5.252 5.593 6.187 7.407 8.409 4.454 0.0269633 REC8 homolog (yeast) PEBP4 4.314 0.648 3.195 4.972 5.351 5.606 4.457 0.0294298 phosphatidylethanolamine-binding protein 4 LOC440335 4.423 5.078 6.672 6.994 9.779 6.579 4.458 0.0438028 No description TBC1D10C 1.648 2.450 2.450 3.830 3.805 5.926 4.458 0.0231192 TBC1 domain family, member 10C APOO 1.648 3.420 1.648 4.721 3.805 4.104 4.458 0.0313369 apolipoprotein O EXD2 6.487 4.151 4.109 7.469 7.010 6.265 4.459 0.0442187 exonuclease 3′-5′ domain containing 2 IL23A 3.194 4.435 5.459 6.666 5.351 6.722 4.461 0.0471477 interleukin 23, alpha subunit p19 SCN11A 5.322 3.859 4.273 6.715 6.489 6.017 4.465 0.0243504 sodium channel, voltage-gated, type XI, alpha subunit KIF21B 5.548 3.233 3.479 5.394 6.839 7.233 4.472 0.0280461 kinesin family member 21B VILL 5.322 3.956 4.276 6.688 6.119 7.226 4.476 0.0184440 villin-like LRRC57 4.793 3.409 3.773 5.939 5.682 6.350 4.489 0.0204925 leucine rich repeat containing 57 SCAND2 5.431 5.626 6.260 7.723 7.996 7.797 4.504 0.0111206 SCAN domain containing 2 pseudogene SIDT2 7.170 6.106 6.466 8.638 8.404 9.265 4.507 0.0135636 SID1 transmembrane family, member 2 SAPS1 8.366 7.626 9.359 10.540 10.618 10.386 4.510 0.0207054 No description DUS1L 7.162 6.422 7.900 9.557 9.881 8.595 4.510 0.0200045 dihydrouridine synthase 1-like (S. cerevisiae) HIRA 6.150 5.658 5.685 7.596 8.354 7.859 4.513 0.0107955 HIR histone cell cycle regulation defective homolog A (S. cerevisiae) C6orf1 5.849 5.237 5.586 8.026 7.784 6.919 4.523 0.0163477 chromosome 6 open reading frame 1 ALPP 8.402 7.559 8.360 9.752 10.259 10.581 4.531 0.0142478 alkaline phosphatase, placental PRPSAP1 6.476 4.984 5.319 6.859 8.613 8.656 4.531 0.0194499 phosphoribosyl pyrophosphate synthetase-associated protein 1 KIF9 2.648 4.719 3.283 5.463 5.813 5.233 4.532 0.0313598 kinesin family member 9 TRMT2A 3.648 5.684 4.903 7.084 7.201 6.743 4.534 0.0190541 TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae) FBXO40 1.648 1.648 1.834 3.830 3.499 4.104 4.537 0.0080205 F-box protein 40 CNGB1 3.422 1.648 1.978 3.830 4.174 4.692 4.537 0.0327158 cyclic nucleotide gated channel beta 1 DZIP1L 4.525 3.293 5.366 5.845 6.952 6.707 4.537 0.0277445 DAZ interacting protein 1-like MRPL20 4.709 6.341 5.637 7.822 8.305 7.303 4.548 0.0173688 mitochondrial ribosomal protein L20 IDH3G 6.716 6.456 5.992 8.901 8.723 8.036 4.549 0.0116711 Description ADCY2 5.482 4.094 5.426 6.326 6.544 7.669 4.553 0.0360205 adenylate cyclase 2 (brain) C7orf63 2.233 3.130 4.204 6.104 5.172 5.320 4.563 0.0181764 chromosome 7 open reading frame 63 POM121L8P 4.482 4.603 4.225 6.418 6.418 6.877 4.573 0.0076080 POM121 membrane glycoprotein-like 8 pseudogene NOL12 5.661 4.699 5.004 7.499 7.197 7.085 4.575 0.0112475 nucleolar protein 12 XPO5 5.171 6.024 5.862 8.218 8.218 7.263 4.576 0.0132288 exportin 5 LOC642587 8.285 6.955 6.607 9.077 11.651 8.801 4.577 0.0278832 No description FLJ45445 7.991 6.827 2.401 9.159 9.022 9.017 4.578 0.0303282 No description BMS1 5.781 5.277 6.434 7.976 8.230 7.677 4.579 0.0136225 BMS1 homolog, ribosome assembly protein (yeast) HEBP2 5.644 4.907 5.151 7.839 7.748 6.528 4.580 0.0170908 heme binding protein 2 LYSMD2 4.734 4.317 4.363 6.560 6.952 5.516 4.583 0.0245397 LysM, putative peptidoglycan-binding, domain containing 2 PTRH1 5.503 6.234 6.910 8.873 9.106 7.668 4.584 0.0170679 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) MCM7 7.417 7.184 7.722 8.941 9.614 10.258 4.585 0.0142568 minichromosome maintenance complex component 7 NUFIP1 4.142 4.547 5.199 7.471 6.744 5.674 4.586 0.0276669 nuclear fragile X mental retardation protein interacting protein 1 EIF3J 8.143 8.585 9.281 10.051 11.480 11.148 4.593 0.0176059 eukaryotic translation initiation factor 3, subunit J LOC646851 7.073 5.762 5.884 8.020 8.355 8.086 4.604 0.0221993 No description UPP2 2.233 5.252 5.588 6.556 7.458 7.497 4.613 0.0237924 uridine phosphorylase 2 BLOC1S1 8.514 7.468 8.407 10.812 10.144 9.675 4.618 0.0183809 biogenesis of lysosomal organelles complex-1, subunit 1 TMUB1 7.443 5.375 7.975 10.091 9.651 9.253 4.620 0.0160260 transmembrane and ubiquitin-like domain containing 1 C19orf24 4.709 5.266 4.257 6.917 7.407 6.472 4.621 0.0132718 chromosome 19 open reading frame 24 CAPG 7.165 6.818 7.603 9.292 9.335 9.813 4.625 0.0079955 capping protein (actin filament), gelsolin-like STOML1 3.860 0.648 3.046 5.256 5.894 5.158 4.630 0.0172489 stomatin (EPB72)-like 1 LAMA4 10.722 8.928 10.360 12.818 12.283 12.571 4.630 0.0118187 laminin, alpha 4 SDHAP2 3.860 4.189 5.613 6.631 6.052 7.825 4.635 0.0244967 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2 RDH5 6.312 4.043 5.487 7.912 7.554 7.701 4.638 0.0169723 retinol dehydrogenase 5 (11-cis/9-cis) CD22 1.648 2.894 2.281 4.017 3.892 5.108 4.639 0.0216953 CD22 molecule DIO3OS 1.648 1.648 2.894 4.725 2.739 5.108 4.639 0.0356607 DIO3 opposite strand (non-protein coding) MLX 8.043 6.366 6.733 9.752 9.630 8.580 4.639 0.0196932 MAX-like protein X ZC3H7B 6.260 5.253 5.530 8.222 7.744 7.551 4.639 0.0125542 zinc finger CCCH-type containing 7B RPL18 11.785 11.262 12.334 14.000 13.952 14.405 4.643 0.0090222 ribosomal protein L18 PHF20 7.331 6.885 6.107 9.547 9.053 8.953 4.644 0.0094756 PHD finger protein 20 MGC70857 7.295 4.189 6.800 9.412 9.015 8.258 4.645 0.0208232 No description DKFZp761E198 6.845 7.153 7.608 10.263 9.118 9.062 4.648 0.0131324 No description IL10 6.742 5.081 5.878 7.719 7.924 8.959 4.650 0.0183380 interleukin 10 RPS6KA4 6.776 5.828 7.737 8.993 9.496 8.823 4.650 0.0167338 ribosomal protein S6 kinase, 90 kDa, polypeptide 4 ZSCAN21 2.648 3.791 4.340 6.296 6.009 5.255 4.652 0.0183151 zinc finger and SCAN domain containing 21 LLGL2 3.233 4.122 5.577 6.344 7.702 6.300 4.664 0.0221244 lethal giant larvae homolog 2 (Drosophila) ARFGAP1 3.648 4.091 4.998 7.220 6.610 5.551 4.664 0.0214693 ADP-ribosylation factor GTPase activating protein 1 RHBDL3 4.108 4.334 4.799 6.331 6.551 8.147 4.670 0.0122104 rhomboid, veinlet-like 3 (Drosophila) LOC652276 3.947 4.427 3.290 6.171 5.854 6.239 4.674 0.0114146 No description LOC285456 1.648 2.304 2.926 4.477 4.529 5.082 4.676 0.0101272 No description DHX34 3.648 4.143 4.826 5.883 6.647 6.369 4.676 0.0156496 DEAN (Asp-Glu-Ala-His) box polypeptide 34 MED11 5.870 4.713 4.381 8.015 7.806 6.612 4.693 0.0147823 mediator complex subunit 11 RFXANK 7.338 6.036 6.688 9.570 8.864 8.598 4.700 0.0130686 regulatory factor X-associated ankyrin-containing protein ILFS 8.343 8.291 8.005 9.842 10.524 10.889 4.702 0.0106125 interleukin enhancer binding factor 3, 90 kDa ISOC2 6.495 6.422 6.904 9.137 8.999 8.137 4.702 0.0123109 isochorismatase domain containing 2 TMEM176A 2.648 3.297 2.648 4.883 4.618 5.665 4.706 0.0125903 transmembrane protein 176A GPAT2 5.572 3.607 4.376 7.811 6.639 5.346 4.719 0.0429002 glycerol-3-phosphate acyltransferase 2, mitochondrial PMF1 7.726 6.546 6.453 8.965 9.082 8.693 4.724 0.0187317 polyamine-modulated factor 1 PHF5A 6.692 6.670 7.021 9.262 9.090 8.654 4.726 0.0072877 PHD finger protein 5A HDAC6 6.499 5.544 6.473 7.841 7.832 8.741 4.730 0.0205487 histone deacetylase 6 MY019 5.291 5.819 6.158 8.050 8.401 7.563 4.733 0.0106638 myosin XIX RBM15B 6.993 7.764 7.011 9.653 9.415 9.239 4.745 0.0096870 RNA binding motif protein 15B FAM 1640 2.233 2.233 2.524 4.276 4.777 4.481 4.748 0.0064898 family with sequence similarity 164, member C KCTD17 2.233 3.717 2.233 5.610 4.777 4.481 4.748 0.0196752 potassium channel tetramerisation domain containing 17 CHST5 4.525 2.233 2.461 5.041 5.479 4.481 4.748 0.0432898 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 OGDH 8.375 6.828 7.553 10.007 9.804 9.075 4.750 0.0226354 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) PSMG4 5.861 5.256 5.170 7.420 8.091 8.087 4.757 0.0067393 proteasome (prosome, macropain) assembly chaperone 4 BCL2L11 8.932 8.235 9.134 10.769 10.528 11.385 4.759 0.0137598 BCL2-like 11 (apoptosis facilitator) MT1L 4.008 5.576 5.658 6.259 7.144 8.187 4.760 0.0318957 metallothionein 1L (gene/pseudogene) ZNF592 6.576 6.534 7.101 9.223 8.785 9.323 4.761 0.0058853 zinc finger protein 592 ZBTB40 7.017 6.348 7.175 8.601 9.037 9.681 4.765 0.0120579 zinc finger and BTB domain containing 40 FBXL14 3.422 2.121 2.234 4.376 4.421 5.862 4.771 0.0195823 F-box and leucine-rich repeat protein 14 FOXF2 7.304 6.997 7.315 9.562 8.383 10.246 4.781 0.0188780 forkhead box F2 ZNF500 4.378 3.621 4.399 6.124 6.657 5.889 4.784 0.0134513 zinc finger protein 500 NDOR1 5.846 4.967 5.917 8.175 8.010 8.002 4.784 0.0061043 NADPH dependent diflavin oxidoreductase 1 ERAL1 4.709 5.655 5.086 8.460 7.344 6.617 4.785 0.0173029 Era G-protein-like 1 (E. coli)) SRRD 5.739 4.587 4.602 7.378 7.806 6.847 4.789 0.0122014 SRR1 domain containing PPP1R9B 9.229 6.461 7.835 9.530 10.096 10.669 4.793 0.0306430 protein phosphatase 1, regulatory (inhibitor) subunit 9B USP40 7.140 5.094 5.951 8.327 8.214 8.198 4.800 0.0209390 ubiquitin specific peptidase 40 MARS 9.247 9.005 8.605 11.772 11.270 9.812 4.806 0.0283428 methionyl-tRNA synthetase TP53H3 7.149 5.926 7.730 9.996 9.164 9.388 4.810 0.0118277 tumor protein p53 inducible protein 13 RPS6 14.301 13.212 15.081 16.567 16.806 15.813 4.810 0.0215816 ribosomal protein S6 VPS16 5.377 5.599 5.435 8.357 7.703 7.528 4.817 0.0060523 vacuolar protein sorting 16 homolog (S. cerevisiae) LIG4 1.648 4.952 4.485 7.220 6.665 5.082 4.819 0.0333598 ligase IV, DNA, ATP-dependent TRAF4 10.195 9.202 10.171 11.470 13.043 12.333 4.819 0.0139054 TNF receptor-associated factor 4 DYNLL1 10.730 9.630 10.886 11.903 12.513 13.209 4.834 0.0205175 dynein, light chain, LC8-type 1 TMEM86B 2.970 3.601 3.111 5.385 4.361 6.297 4.836 0.0229279 transmembrane protein 86B GLG1 10.521 8.047 9.026 11.761 10.579 11.301 4.840 0.0385889 golgi glycoprotein 1 YTHDF2 9.809 8.829 9.921 12.011 12.124 12.087 4.850 0.0061723 YTH domain family, member 2 FBXL15 6.202 5.514 6.634 8.913 8.001 8.114 4.852 0.0137868 F-box and leucine-rich repeat protein 15 IDUA 7.257 6.247 6.789 8.336 9.067 10.121 4.852 0.0152787 Description TAT 7.421 5.349 6.318 8.597 8.558 8.707 4.852 0.0189140 tyrosine aminotransferase ZNF296 5.109 2.233 4.142 5.892 6.588 6.420 4.852 0.0240010 zinc finger protein 296 CYP2B7P1 1.648 1.648 1.648 5.064 3.805 3.929 4.860 0.0066520 cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1 PQLC2 1.648 1.648 2.776 4.624 4.945 3.929 4.860 0.0107054 PQ loop repeat containing 2 ST7OT1 5.400 4.021 4.189 7.148 6.666 6.304 4.866 0.0172260 ST7 overlapping transcript 1 (non-protein coding) NELF 7.889 8.149 8.987 10.453 10.799 10.171 4.867 0.0138118 nasal embryonic LHRH factor CHCHD6 6.340 3.645 5.292 7.675 7.576 6.791 4.869 0.0291976 coiled-coil-helix-coiled-coil-helix domain containing 6 VPS72 7.661 5.604 7.377 9.661 9.664 8.402 4.870 0.0231012 vacuolar protein sorting 72 homolog (S. cerevisiae) AMZ1 4.264 4.119 3.802 6.549 6.302 6.227 4.871 0.0049834 archaelysin family metallopeptidase 1 FAM127A 3.619 2.649 3.029 5.610 5.314 5.279 4.875 0.0081744 family with sequence similarity 127, member A COLO 2.648 4.178 4.340 5.861 5.813 6.626 4.877 0.0160101 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase LRCH1 8.554 7.720 8.194 10.007 10.254 10.946 4.880 0.0112267 leucine-rich repeats and calponin homology (CH) domain containing 1 IYD 4.895 2.744 3.022 5.835 5.032 6.160 4.884 0.0304530 iodotyrosine deiodinase SHE 4.456 4.853 4.546 6.832 6.744 7.323 4.886 0.0055359 Src homology 2 domain containing E POM121 5.377 4.681 4.850 6.970 7.314 7.289 4.887 0.0076801 POM121 membrane glycoprotein CLEC4E 2.233 3.815 3.972 5.773 4.523 7.778 4.888 0.0263442 C-type lectin domain family 4, member E KDM4D 4.657 2.233 2.461 5.231 4.523 5.637 4.888 0.0418360 lysine (K)-specific demethylase 4D C16orf68 5.821 5.346 6.723 8.572 8.313 7.635 4.889 0.0159407 chromosome 16 open reading frame 68 AFG3L1 4.826 4.356 5.500 7.745 7.117 7.089 4.892 0.0090367 No description APPBP2 5.507 5.804 5.967 7.884 7.800 8.414 4.901 0.0069120 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 C10orf118 4.708 5.264 5.892 7.497 7.557 7.764 4.902 0.0094846 chromosome 10 open reading frame 118 IRF2BP1 6.931 5.389 6.491 8.784 8.905 8.384 4.902 0.0115899 interferon regulatory factor 2 binding protein 1 DGCR8 6.509 6.541 6.731 8.835 9.393 8.143 4.904 0.0121307 DiGeorge syndrome critical region gene 8 APOBEC3G 4.525 4.294 3.620 5.330 6.588 7.742 4.905 0.0208551 apolipoprotein B mRNA editing enzyme, catalytic polypeptide- like 3G TRIM14 5.008 4.465 4.126 6.346 7.010 7.304 4.911 0.0098756 tripartite motif-containing 14 QTRT1 6.968 6.467 7.917 9.266 8.983 9.476 4.918 0.0163712 queuine tRNA-ribosyltransferase 1 DNM1L 6.229 7.009 7.102 9.396 9.308 9.161 4.921 0.0053411 dynamin 1-like LSM10 5.452 4.792 5.313 7.751 7.454 7.224 4.921 0.0071643 LSM10, U7 small nuclear RNA associated RNH1 10.255 9.304 9.734 12.882 12.037 11.419 4.933 0.0136738 ribonuclease/angiogenin inhibitor 1 BAZ1B 7.215 7.229 8.084 9.519 9.818 10.082 4.935 0.0091830 bromodomain adjacent to zinc finger domain, 1B LOC286467 2.233 4.564 5.189 6.288 6.950 6.870 4.948 0.0195400 No description EIF4ENIF1 6.135 5.310 5.848 7.889 8.402 8.157 4.956 0.0067123 eukaryotic translation initiation factor 4E nuclear import factor 1 ASF1A 6.227 5.987 6.610 8.536 8.487 8.708 4.956 0.0055179 ASF1 anti-silencing function 1 homolog A (S. cerevisiae) ITGA10 3.456 5.477 5.468 7.210 7.427 7.788 4.964 0.0133057 integrin, alpha 10 FLJ39582 5.264 2.675 4.852 7.576 7.005 7.062 4.965 0.0123789 No description GPR25 4.647 2.941 3.860 5.256 6.173 6.522 4.970 0.0227664 G protein-coupled receptor 25 LOC643008 4.086 3.486 3.795 6.132 5.801 6.335 4.973 0.0064211 No description GDAP1 4.817 3.508 2.461 5.968 5.824 5.451 4.978 0.0264468 ganglioside-induced differentiation-associated protein 1 ZNF490 5.019 4.307 4.660 6.367 7.174 7.336 4.982 0.0102832 zinc finger protein 490 KHNYN 7.544 6.693 8.143 9.679 10.115 9.863 4.990 0.0103657 KH and NYN domain containing XPC 7.002 5.597 5.788 9.361 7.917 8.091 4.992 0.0183899 xeroderma pigmentosum, complementation group C COG2 4.860 3.957 4.493 7.275 6.812 5.398 4.992 0.0261542 component of oligomeric golgi complex 2 TSPAN31 5.781 5.634 5.646 7.968 7.445 8.114 5.000 0.0078652 tetraspanin 31 RRN3P3 8.852 8.122 9.266 11.378 11.156 11.175 5.004 0.0068433 RNA polymerase l transcription factor homolog (S. cerevisiae) pseudogene 3 SEC31A 10.321 9.100 9.449 12.239 11.773 11.615 5.008 0.0123608 SEC31 homolog A (S. cerevisiae) FMNL3 8.130 6.765 6.695 9.703 8.851 10.455 5.010 0.0159068 formin-like 3 MAP7D1 10.382 9.309 11.191 12.709 13.169 12.636 5.018 0.0120433 MAP7 domain containing 1 FOXD1 3.422 2.894 1.689 5.196 4.017 6.454 5.022 0.0216087 forkhead box D1 ATRIP 5.781 2.926 5.110 7.439 7.813 6.947 5.027 0.0168406 ATR interacting protein HOXB6 4.314 2.401 3.431 6.329 5.462 5.761 5.027 0.0145480 homeobox B6 MRPS25 7.061 6.435 6.649 8.279 8.979 10.334 5.028 0.0149640 mitochondrial ribosomal protein S25 LOC283174 3.233 3.991 3.685 4.590 6.632 6.017 5.035 0.0253730 No description TYMS 3.792 2.648 2.648 5.024 5.977 4.981 5.037 0.0145147 thymidylate synthetase C22orf30 3.648 4.448 4.959 7.515 6.781 5.600 5.041 0.0215123 chromosome 22 open reading frame 30 PCMT1 9.241 8.437 8.383 11.233 10.883 10.718 5.043 0.0094166 protein-L-isoaspartate (D-aspartate) O-methyltransferase SHKBP1 6.398 6.327 6.877 10.141 8.734 8.652 5.050 0.0089674 SH3KBP1 binding protein 1 ACTL7B 0.648 0.648 0.729 3.351 2.987 2.370 5.057 0.0089931 actin-like 7B HAPLN2 0.648 0.648 0.729 3.662 2.987 2.370 5.057 0.0100211 hyaluronan and proteoglycan link protein 2 PLB1 0.648 0.648 0.648 2.202 2.987 3.351 5.057 0.0111341 phospholipase B1 SNORA24 0.648 0.648 0.648 2.202 2.987 3.351 5.057 0.0111341 small nucleolar RNA, H/ACA box 24 CYP46A1 0.648 0.648 0.729 2.202 2.987 3.773 5.057 0.0126083 cytochrome P450, family 46, subfamily A, polypeptide 1 MIR132 0.648 0.648 1.387 2.202 2.987 5.158 5.057 0.0235407 microRNA 132 ATP2A1 0.648 2.593 0.648 4.632 2.987 3.351 5.057 0.0249418 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 TMEM132E 0.648 2.359 2.987 4.854 2.987 5.230 5.057 0.0326003 transmembrane protein 132E PYCRL 5.289 4.237 4.951 6.774 7.474 7.290 5.059 0.0095643 pyrroline-5-carboxylate reductase-like PRR12 6.735 4.901 5.402 8.499 7.480 7.744 5.068 0.0210090 proline rich 12 INTU 3.860 1.477 2.714 3.351 5.351 6.202 5.071 0.0426527 inturned planar cell polarity effector homolog (Drosophila) ACHE 3.792 3.424 3.016 5.748 6.001 5.767 5.073 0.0051470 acetylcholinesterase E2F4 2.648 3.722 4.495 6.066 6.828 5.400 5.077 0.0163567 E2F transcription factor 4, p107/p130-binding FAM32A 7.787 7.990 7.912 10.382 10.133 10.142 5.086 0.0034603 family with sequence similarity 32, member A WDR27 2.970 3.827 2.970 5.919 3.827 6.174 5.086 0.0365192 WD repeat domain 27 TNFAIP8L1 7.740 7.161 7.756 9.951 10.080 10.103 5.086 0.0038548 tumor necrosis factor, alpha-induced protein 8-like 1 C9orf78 6.959 7.732 7.083 9.768 9.314 9.430 5.087 0.0083511 chromosome 9 open reading frame 78 CHD3 8.978 7.175 8.274 10.622 10.083 11.279 5.090 0.0141695 chromodomain helicase DNA binding protein 3 SP4 5.645 5.189 4.635 7.164 7.039 7.994 5.093 0.0128010 Sp4 transcription factor POP1 3.233 3.233 3.261 5.583 6.399 5.349 5.096 0.0057217 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) IKZF2 3.233 4.673 3.877 5.583 5.970 7.062 5.099 0.0187081 IKAROS family zinc finger 2 (Helios) SMYD4 7.218 4.457 5.360 7.711 7.692 8.209 5.102 0.0315719 SET and MYND domain containing 4 KRT27 0.648 0.648 0.729 3.081 2.987 3.043 5.104 0.0021203 keratin 27 KDM2A 9.284 8.699 9.261 11.636 11.186 11.575 5.105 0.0055969 lysine (K)-specific demethylase 2A C10orf140 3.456 3.456 3.523 5.903 4.871 5.809 5.108 0.0139463 chromosome 10 open reading frame 140 HCCS 6.257 6.019 6.483 9.007 8.611 8.329 5.114 0.0054908 holocytochrome c synthase SPRYD4 5.982 4.047 4.033 6.846 6.413 6.388 5.115 0.0384905 SPRY domain containing 4 RPL9 13.044 13.083 13.458 15.461 15.813 15.201 5.116 0.0062222 ribosomal protein L9 MFSD11 7.298 4.747 5.467 7.853 7.490 7.822 5.117 0.0450589 major facilitator superfamily domain containing 11 POLA1 2.233 2.233 2.814 6.139 3.958 4.590 5.123 0.0165085 polymerase (DNA directed), alpha 1, catalytic subunit DUS3L 6.732 5.891 7.892 9.299 9.881 8.249 5.126 0.0240440 dihydrouridine synthase 3-like (S. cerevisiae) GINS1 3.792 3.202 3.533 4.273 6.151 6.107 5.129 0.0295809 GINS complex subunit 1 (Psf1 homolog) DUS2L 1.648 3.423 3.023 5.601 5.783 3.557 5.135 0.0311588 dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae) AP1S1 6.392 4.435 4.529 8.272 7.128 6.798 5.143 0.0256087 adaptor-related protein complex 1, sigma 1 subunit ZNF335 6.472 6.168 7.567 8.835 9.036 8.781 5.145 0.0153778 zinc finger protein 335 XIRP1 4.086 5.451 5.902 5.651 7.815 8.329 5.147 0.0454610 xin actin-binding repeat containing 1 ERMP1 4.793 3.233 3.545 6.259 6.465 5.598 5.151 0.0168912 endoplasmic reticulum metallopeptidase 1 GPR133 4.539 4.510 5.553 7.918 6.485 7.399 5.152 0.0137958 G protein-coupled receptor 133 TMEM149 5.042 1.648 3.435 5.805 5.120 5.802 5.159 0.0420704 transmembrane protein 149 CEP192 3.860 1.387 3.043 5.256 5.411 5.606 5.160 0.0147442 centrosomal protein 192 kDa ZNF169 1.648 1.648 1.689 4.662 4.017 3.557 5.166 0.0072517 zinc finger protein 169 GP5 1.648 1.648 1.689 4.017 3.247 4.692 5.166 0.0112925 glycoprotein V (platelet) GRM2 1.648 1.648 1.978 4.017 2.739 4.830 5.166 0.0244815 glutamate receptor, metabotropic 2 HSPA1L 1.648 2.601 3.841 4.931 4.017 7.633 5.166 0.0282679 heat shock 70 kDa protein 1 -like RNF112 4.423 1.648 2.458 5.459 4.017 6.351 5.166 0.0340073 ring finger protein 112 FAM73B 5.899 5.681 6.259 8.389 8.271 8.269 5.177 0.0044419 family with sequence similarity 73, member B C2orf15 7.533 6.811 7.285 9.375 9.658 9.858 5.179 0.0055789 chromosome 2 open reading frame 15 SRP72 8.037 7.503 6.290 10.411 8.922 9.039 5.184 0.0256315 signal recognition particle 72 kDa TIPRL 6.834 6.896 6.290 9.329 8.758 8.665 5.187 0.0086166 TIP41, TOR signaling pathway regulator-like (S. cerevisiae) TAF10 8.832 7.280 8.270 10.645 10.863 10.596 5.188 0.0085896 TAF10 RNA polymerase II, TATA box binding protein (TBP)- associated factor, 30 kDa C9orf114 2.648 3.766 4.148 6.774 5.993 5.026 5.197 0.0179199 chromosome 9 open reading frame 114 MRPL32 9.291 8.689 8.574 10.953 11.543 11.139 5.201 0.0070201 mitochondrial ribosomal protein L32 PELI3 5.235 4.092 4.926 7.779 6.766 6.472 5.205 0.0160745 pellino homolog 3 (Drosophila) FAAH 3.422 3.209 4.453 5.731 6.086 5.802 5.207 0.0135906 fatty acid amide hydrolase RUNDC2C 3.456 3.830 4.157 5.073 6.436 6.538 5.210 0.0169633 RUN domain containing 20 ADSSL1 5.452 3.209 2.601 5.102 5.591 7.566 5.215 0.0435560 adenylosuccinate synthase like 1 TEP1 5.789 5.445 6.146 8.332 8.529 7.667 5.217 0.0079366 telomerase-associated protein 1 LOC283314 5.594 5.031 5.301 7.419 7.715 7.804 5.234 0.0052780 No description RNF123 6.492 5.877 5.960 8.881 8.400 7.960 5.239 0.0089494 ring finger protein 123 CROP 5.346 4.905 4.876 6.742 7.438 7.737 5.244 0.0098485 CGRP receptor component UTS2D 2.233 3.047 3.983 5.773 4.624 5.842 5.245 0.0187407 urotensin 2 domain containing SLC10A7 4.525 2.233 2.524 5.167 4.624 5.279 5.245 0.0405438 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 DOT1L 9.224 8.417 10.187 11.615 11.692 11.379 5.246 0.0154173 DOT1-like, histone H3 methyltransferase (S. cerevisiae) TUBE1 4.620 5.243 5.352 8.111 7.636 6.612 5.253 0.0126603 tubulin, epsilon 1 HMX3 3.194 0.648 1.649 4.854 4.043 3.351 5.256 0.0305272 H6 family homeobox 3 CBLL1 6.690 6.086 6.285 8.679 8.723 8.482 5.260 0.0057667 Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 ATP1B4 0.648 0.648 0.648 3.351 2.987 3.043 5.260 0.0025477 ATPase, Na+/K+ transporting, beta 4 polypeptide XKR6 0.648 0.648 0.648 3.351 2.987 3.043 5.260 0.0025477 XK, Kell blood group complex subunit-related family, member 6 DNAJB7 0.648 1.078 2.202 4.372 4.428 3.043 5.260 0.0125272 DnaJ (Hsp40) homolog, subfamily B, member 7 PKLR 0.648 0.648 1.245 2.202 3.871 3.043 5.260 0.0175386 pyruvate kinase, liver and RBC CYP2R1 4.264 4.060 4.140 6.218 7.314 6.535 5.260 0.0060433 cytochrome P450, family 2, subfamily R, polypeptide 1 JRK 4.871 4.988 4.727 7.271 7.110 7.425 5.277 0.0031761 jerky homolog (mouse) C1orf135 9.893 9.294 10.856 12.293 12.313 11.795 5.278 0.0180059 chromosome 1 open reading frame 135 CDK2AP2 7.912 6.944 8.556 11.173 9.345 9.780 5.278 0.0232565 cyclin-dependent kinase 2 associated protein 2 UTP6 5.982 6.439 5.474 8.241 8.733 8.382 5.281 0.0061813 UTP6, small subunit (SSU) processome component, homolog (yeast) PPP1R16B 5.936 3.456 3.859 5.857 5.858 8.633 5.284 0.0451726 protein phosphatase 1. regulatory (inhibitor) subunit 16B NFIC 9.760 7.601 7.954 11.323 10.280 10.357 5.290 0.0264849 nuclear factor l/C (CCAAT-binding transcription factor) CCNJ 3.233 4.087 4.138 6.541 5.970 5.927 5.291 0.0093986 cyclin J PPIF 8.249 8.578 9.142 10.822 11.257 10.981 5.291 0.0071553 peptidylprolyl isomerase F DBF4B 8.151 7.640 7.907 10.046 10.294 10.611 5.299 0.0048932 DBF4 homolog B (S. cerevisiae) C11orf53 0.648 3.336 3.873 6.103 5.742 5.158 5.299 0.0161244 chromosome 11 open reading frame 53 GATSL3 5.042 4.692 5.288 7.099 7.420 7.934 5.306 0.0059033 GATS protein-like 3 CARDIO 6.340 4.285 4.830 6.910 9.220 6.693 5.307 0.0303532 caspase recruitment domain family, member 10 HAVCR2 4.525 2.233 3.686 6.098 4.889 6.707 5.322 0.0248024 hepatitis A virus cellular receptor 2 SHF 6.713 5.167 6.258 8.436 8.570 9.128 5.333 0.0084815 Src homology 2 domain containing F ZNF321 7.068 6.892 7.874 9.310 9.635 9.947 5.344 0.0089064 zinc finger protein 321 SF3B2 8.186 8.042 8.130 10.796 10.549 9.833 5.346 0.0084371 splicing factor 3b, subunit 2, 145 kDa WFDC8 3.194 1.245 2.593 5.407 4.602 5.014 5.355 0.0114416 WAP four-dlsulfide core domain 8 ACSL4 6.317 6.394 6.678 9.096 8.876 8.739 5.357 0.0034139 acyl-CoA synthetase long-chain family member 4 PREX2 2.648 2.648 3.311 5.072 4.896 6.034 5.364 0.0090021 phosphatidylinositol-3,4,5-trisphosphate-dependent Rae exchange factor 2 SHOX2 7.265 6.667 6.672 9.095 8.204 9.797 5.365 0.0174756 short stature homeobox 2 TUBB2C 10.754 11.200 11.438 12.578 13.676 13.862 5.368 0.0139282 tubulin, beta 2C CESS 2.970 3.712 3.111 4.754 5.889 6.140 5.381 0.0132808 carboxylesterase 3 ZNF623 4.525 2.932 3.323 5.845 5.360 6.234 5.381 0.0176329 zinc finger protein 623 TSG101 8.379 7.549 8.464 12.102 10.807 9.940 5.383 0.0110083 tumor susceptibility gene 101 THUMPD3 2.233 2.814 2.233 4.722 5.244 3.054 5.390 0.0370707 THUMP domain containing 3 TIMM13 8.389 7.927 9.322 10.820 11.640 10.454 5.394 0.0132017 translocase of inner mitochondrial membrane 13 homolog (yeast) FAM166B 0.648 0.648 0.648 3.081 2.987 3.351 5.398 0.0024260 family with sequence similarity 166, member B TMCO2 0.648 0.648 0.648 3.081 2.987 4.748 5.398 0.0066340 transmembrane and coiled-coil domains 2 RBM41 0.648 0.648 0.648 3.081 3.633 2.370 5.398 0.0088260 RNA binding motif protein 41 CLDND2 0.648 0.648 1.962 3.081 3.633 3.966 5.398 0.0114055 claudin domain containing 2 DYSFIP1 0.648 0.648 1.649 3.081 2.353 4.262 5.398 0.0212419 dysferlin interacting protein 1 UBE2Q2P3 0.648 1.962 2.202 3.081 3.284 5.407 5.398 0.0293522 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 3 INCA1 3.860 0.648 1.245 3.081 5.053 4.602 5.398 0.0441279 inhibitor of CDK, cyclin A1 interacting protein 1 ADAT3 6.924 4.857 6.967 8.986 9.399 9.302 5.400 0.0092593 adenosine deaminase, tRNA-specific 3, TAD3 homolog (S. cerevisiae) DGKQ 5.664 2.970 4.070 6.504 7.003 6.188 5.403 0.0256967 diacylglycerol kinase, theta 110 kDa C17orf63 6.676 6.658 7.042 9.328 9.476 8.361 5.404 0.0109674 chromosome 17 open reading frame 63 MPPE1 4.619 3.615 5.355 6.463 7.054 7.135 5.407 0.0148856 metallophosphoesterase 1 ALG13 1.648 3.023 4.174 5.459 6.219 4.975 5.410 0.0182555 asparagine-linked glycosylation 13 homolog (S. cerevisiae) DGKE 6.455 6.470 6.994 8.721 8.906 9.444 5.412 0.0065979 diacylglycerol kinase, epsilon 64 kDa LOC400043 8.603 6.728 6.883 9.320 9.164 9.475 5.413 0.0315380 No description ERIS 7.988 6.517 7.764 10.458 9.969 8.953 5.415 0.0174270 ERI1 exoribonuclease family member 3 INPP5D 3.792 3.251 3.888 5.691 5.977 8.251 5.427 0.0119851 inositol polyphosphate-5-phosphatase, 145 kDa LTB4R 2.648 3.297 3.967 6.411 6.115 4.579 5.438 0.0185314 leukotriene B4 receptor RNF208 2.233 3.508 3.029 5.952 5.416 4.955 5.440 0.0097799 ring finger protein 208 CHST6 6.522 6.243 5.659 8.483 8.687 8.922 5.441 0.0048274 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 SFH 3.947 3.511 4.650 6.391 6.969 6.100 5.443 0.0093113 Sfi1 homolog, spindle assembly associated (yeast) C8or73 5.600 3.178 3.126 5.571 5.934 6.411 5.444 0.0432510 chromosome 8 open reading frame 73 LOC100130776 3.422 4.051 4.926 6.666 6.534 5.869 5.455 0.0159962 No description UNC13D 3.648 4.800 5.761 6.978 7.236 8.211 5.462 0.0128641 unc-13 homolog D (C. elegans) DPF2 6.196 5.399 6.864 8.648 8.566 8.731 5.471 0.0088010 D4. zinc and double PHD fingers family 2 DDHD2 4.580 4.579 4.269 7.151 7.033 6.653 5.479 0.0037348 DDHD domain containing 2 NT5DC3 7.493 7.525 6.442 8.509 10.635 9.947 5.481 0.0163802 5′-nucleotidase domain containing 3 CXCL1 7.367 8.304 8.644 10.120 10.908 10.758 5.481 0.0096094 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) DPP3 4.525 4.532 4.916 7.505 6.987 6.074 5.481 0.0144177 dipeptidyl-peptidase 3 C9orf80 5.945 4.181 5.551 8.046 8.006 7.926 5.482 0.0079726 chromosome 9 open reading frame 80 NSFL1C 8.260 8.611 9.392 11.781 11.847 10.596 5.483 0.0091920 NSFL1 (p97) cofactor (p47) PLCH2 1.648 1.648 1.648 3.326 5.405 4.104 5.486 0.0115601 phospholipase C, eta 2 RBM44 1.648 3.475 1.648 4.721 5.120 4.104 5.486 0.0184080 RNA binding motif protein 44 WDHD1 1.648 1.648 1.648 4.624 2.739 4.104 5.486 0.0196572 WD repeat and HMG-box DNA binding protein 1 FLJ10213 1.648 1.648 1.648 4.154 2.739 4.104 5.486 0.0200981 No description IKBKB 5.640 6.072 6.393 8.456 8.529 8.809 5.491 0.0040669 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta EFHC1 5.507 5.652 5.548 7.680 8.100 8.109 5.492 0.0037168 EF-hand domain (C-terminal) containing 1 MY010 8.067 6.874 7.180 9.332 9.815 9.800 5.493 0.0113432 myosin X SLC2A8 5.587 3.202 4.432 6.891 7.266 6.835 5.496 0.0150832 solute carrier family 2 (facilitated glucose transporter), member 8 RHOF 4.086 3.861 4.201 4.535 6.769 6.547 5.505 0.0400128 ras homolog gene family, member F (in filopodia) GIGYF1 7.565 7.333 8.150 10.137 9.982 10.027 5.510 0.0060295 GRB10 interacting GYF protein 1 VN1R2 2.233 2.461 2.570 4.869 5.078 4.697 5.515 0.0032621 vomeronasal 1 receptor 2 AVPI1 6.036 4.477 4.833 7.296 7.122 7.858 5.516 0.0149549 arginine vasopressin-induced 1 FUT5 4.142 2.702 2.822 5.167 5.458 6.290 5.521 0.0143705 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) TNFRSF6B 6.340 4.174 6.102 8.568 8.711 7.484 5.529 0.0152697 tumor necrosis factor receptor superfamily, member 6b, decoy USP54 5.235 4.675 5.561 7.702 7.763 7.256 5.532 0.0068343 ubiquitin specific peptidase 54 ACOT7 8.502 5.824 8.062 9.559 10.602 10.530 5.534 0.0173120 acyl-CoA thioesterase 7 NHEJ1 6.135 5.576 6.520 8.604 8.673 8.580 5.535 0.0047823 nonhomologous end-joining factor 1 HN1L 8.515 7.920 8.543 10.389 11.133 10.662 5.536 0.0068614 hematological and neurological expressed 1 -like GTF2IRD1 5.945 6.047 6.952 8.608 9.024 8.416 5.544 0.0091026 GTF2I repeat domain containing 1 SLC23A2 6.427 5.127 5.238 7.711 7.935 7.602 5.549 0.0151234 solute carrier family 23 (nucleobase transporters), member 2 GFM1 5.899 5.836 5.465 8.308 8.486 7.309 5.549 0.0109404 G elongation factor, mitochondrial 1 KCNK6 3.233 3.714 3.924 5.708 5.816 6.499 5.560 0.0076260 potassium channel, subfamily K, member 6 TMEM53 6.189 4.110 6.621 8.666 8.923 8.460 5.568 0.0103463 transmembrane protein 53 POU2F2 3.818 5.285 4.794 7.366 5.382 7.762 5.569 0.0322631 POU class 2 homeobox 2 C1orf84 4.817 2.649 4.526 7.004 6.491 7.054 5.570 0.0108655 chromosome 1 open reading frame 84 TIE1 7.977 2.648 5.810 8.767 8.027 8.288 5.572 0.0397542 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 DDTL 2.233 3.870 5.064 6.297 7.199 6.349 5.574 0.0145328 D-dopachrome tautomerase-like OVGP1 3.422 2.894 2.601 4.017 5.903 5.770 5.583 0.0212010 oviductal glycoprotein 1, 120 kDa TECR 9.400 7.745 8.252 10.740 10.883 10.712 5.607 0.0139636 trans-2,3-enoyl-CoA reductase SOLE 3.619 3.589 3.902 6.578 5.879 6.109 5.621 0.0044239 squalene epoxidase CNTD2 6.227 3.696 5.310 6.131 7.801 9.169 5.621 0.0303899 cyclin N-terminal domain containing 2 OBSCN 6.209 5.364 6.521 7.361 8.700 9.029 5.624 0.0176239 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF HIVEP3 6.987 6.767 7.062 7.920 9.482 9.963 5.638 0.0222825 human immunodeficiency virus type I enhancer binding protein 3 RNF26 6.912 5.751 6.810 9.408 9.018 8.823 5.639 0.0072156 ring finger protein 26 ANKMY1 4.008 3.059 3.544 6.619 6.040 4.376 5.642 0.0282977 ankyrin repeat and MYND domain containing 1 PRPSAP2 7.568 5.865 5.222 9.915 7.721 8.867 5.654 0.0228697 phosphoribosyl pyrophosphate synthetase-associated protein 2 LRP3 9.575 6.841 7.193 10.137 9.341 10.001 5.657 0.0496239 low density lipoprotein receptor-related protein 3 PEX16 6.103 6.051 6.695 9.195 8.697 7.836 5.657 0.0127428 peroxisomal biogenesis factor 16 SHISA4 6.398 4.174 4.631 7.356 6.675 7.187 5.659 0.0334049 shisa homolog 4 (Xenopus laevis) DPY19L2P2 4.657 2.814 2.778 5.610 5.561 5.279 5.662 0.0261750 dpy-19-like 2 pseudogene 2 (C. elegans) ZNF274 6.340 5.628 6.312 9.129 8.769 8.132 5.671 0.0063761 zinc finger protein 274 PPP1R3F 6.714 5.154 5.703 8.882 7.842 8.209 5.680 0.0129584 protein phosphatase 1, regulatory (inhibitor) subunit 3F FGF5 5.173 4.492 5.310 7.455 7.039 7.816 5.680 0.0073286 fibroblast growth factor 5 PARD6A 1.648 1.648 1.689 4.154 3.247 4.493 5.681 0.0104156 par-6 partitioning defective 6 homolog alpha (C. elegans) SULT2B1 1.648 1.648 1.689 4.154 7.200 2.752 5.681 0.0246853 sulfotransferase family, cytosolic, 2B, member 1 CNTN4 4.423 1.648 1.978 4.154 4.945 6.261 5.681 0.0338402 contactin 4 NEURL2 5.264 2.776 3.077 5.502 5.591 7.140 5.713 0.0302756 neuralized homolog 2 (Drosophila) CST7 6.490 6.655 4.734 7.995 7.265 9.174 5.733 0.0318270 cystatin F (leukocystatin) PL AU 10.199 8.397 8.928 12.719 11.986 10.247 5.735 0.0250416 plasminogen activator, urokinase MHP 6.418 4.700 3.904 7.220 7.613 7.172 5.737 0.0235747 migration and invasion inhibitory protein NXF1 10.852 10.034 10.767 12.479 13.291 13.582 5.754 0.0077321 nuclear RNA export factor 1 INSL3 1.648 1.648 1.978 4.017 4.174 5.512 5.758 0.0063581 insulin-like 3 (Leydig cell) ZNF845 1.648 1.648 2.064 5.272 4.174 3.557 5.758 0.0106825 zinc finger protein 845 CD79A 1.648 1.648 2.121 3.557 4.174 5.289 5.758 0.0110617 CD79a molecule, immunoglobulin-associated alpha LOC100170939 3.422 1.648 1.834 4.721 4.174 4.692 5.758 0.0192912 No description TULP2 4.008 1.648 1.689 5.196 4.174 6.394 5.758 0.0201778 tubby like protein 2 WFIKKN1 2.233 3.073 2.932 3.981 5.458 6.234 5.758 0.0175296 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 CNTFR 6.713 3.510 4.889 7.416 6.851 7.904 5.765 0.0324080 ciliary neurotrophic factor receptor ST20 0.648 0.648 1.245 2.714 3.284 3.773 5.765 0.0084281 suppressor of tumorigenicity 20 CHMP1A 9.056 8.199 8.903 11.504 11.431 10.807 5.768 0.0063310 chromatin modifying protein 1A PHB2 11.122 9.677 11.602 13.653 13.722 13.241 5.778 0.0099116 prohibitin 2 TGFB2 7.261 7.356 7.414 7.798 9.889 10.321 5.785 0.0389050 transforming growth factor, beta 2 MAST2 8.232 7.217 9.054 10.186 10.399 11.587 5.788 0.0153029 microtubule associated serine/threonine kinase 2 MRPL12 7.693 7.320 7.201 10.160 10.228 8.572 5.794 0.0176149 mitochondrial ribosomal protein L12 HTR7P 4.142 2.702 4.417 6.952 6.654 6.293 5.795 0.0073695 No description BAIAP2L1 7.362 6.084 7.107 8.621 11.266 8.696 5.804 0.0214291 BAH-associated protein 2-like 1 LRRC4B 5.452 2.234 4.097 7.446 5.060 6.634 5.804 0.0382818 leucine rich repeat containing 4B SESN1 7.203 6.346 5.537 9.324 8.077 9.352 5.815 0.0138783 sestrin 1 GIT1 6.290 4.117 5.637 8.034 8.178 8.233 5.821 0.0102922 G protein-coupled receptor kinase interacting ArfGAP 1 KCNRG 1.648 1.648 1.834 4.376 3.805 4.376 5.822 0.0039948 potassium channel regulator CDKN2A 7.001 5.075 5.523 8.814 7.769 8.066 5.826 0.0187816 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) SOX5 5.169 2.233 2.607 5.696 4.777 7.389 5.830 0.0328627 SRY (sex determining region Y)-box 5 FAM55C 7.304 5.595 5.041 7.949 8.140 8.575 5.839 0.0240530 family with sequence similarity 55, member C RBM39 9.438 10.031 9.513 12.113 11.192 12.578 5.844 0.0126354 RNA binding motif protein 39 SHROOM1 5.849 3.982 4.953 7.577 7.501 6.745 5.848 0.0167068 shroom family member 1 SNRPA 8.842 7.493 8.741 11.397 10.536 10.938 5.878 0.0093203 small nuclear ribonucleoprotein polypeptide A CHST9 2.233 2.391 2.570 4.804 5.126 4.908 5.883 0.0024711 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 PI4K2A 9.643 9.633 10.693 12.113 12.543 13.251 5.889 0.0081466 phosphatidylinositol 4-kinase type 2 alpha MZF1 5.552 5.555 6.338 8.112 8.321 8.148 5.898 0.0063400 myeloid zinc finger 1 PDE4C 4.349 4.387 4.580 6.949 6.344 7.261 5.907 0.0062132 phosphodiesterase 4C, cAMP-specific APOA1 4.647 2.593 3.143 4.748 6.666 7.209 5.907 0.0200711 apolipoprotein A-l DMXL1 5.920 4.770 4.899 8.314 7.333 7.474 5.909 0.0100641 Dmx-like 1 WDR43 7.898 8.007 7.782 9.862 10.967 10.461 5.913 0.0058672 WD repeat domain 43 TTC32 5.104 3.934 4.250 7.262 6.579 6.815 5.917 0.0087581 tetratricopeptide repeat domain 32 C12orf10 8.314 7.730 7.649 10.879 10.300 10.195 5.917 0.0050790 chromosome 12 open reading frame 10 MCM5 7.876 5.466 6.717 9.396 8.932 9.284 5.927 0.0165917 minichromosome maintenance complex component 5 C2orf14 3.194 4.647 4.990 6.811 7.215 7.380 5.932 0.0078153 chromosome 2 open reading frame 14 C5orf56 2.233 2.360 2.233 4.804 4.729 5.304 5.941 0.0024621 chromosome 5 open reading frame 56 KRBA2 7.394 6.075 6.953 9.507 9.526 9.546 5.953 0.0053591 KRAB-A domain containing 2 UCKL1 7.949 6.414 7.805 10.523 10.076 9.721 5.955 0.0086832 uridine-cytidine kinase 1-like 1 PSMD1 8.215 8.900 9.427 12.336 11.471 10.789 5.956 0.0099442 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 INPP5K 4.214 5.296 4.875 7.452 6.595 8.152 5.967 0.0105764 inositol polyphosphate-5-phosphatase K MRPL48 5.870 3.256 4.381 7.261 6.966 6.006 5.999 0.0303712 mitochondrial ribosomal protein L48 MRPL14 8.726 8.124 7.274 10.711 11.196 10.599 6.008 0.0060114 mitochondrial ribosomal protein L14 ST6GALNAC4 8.204 5.889 7.513 10.793 9.636 8.886 6.015 0.0216482 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N- acetylgalactosaminide alpha-2,6-sialyltransferase 4 LAMP3 2.970 3.802 3.471 5.561 6.172 6.378 6.023 0.0054097 lysosomal-associated membrane protein 3 AES 11.673 9.728 10.884 13.376 13.475 13.484 6.024 0.0098666 amino-terminal enhancer of split DDA1 9.278 8.660 9.334 11.737 12.015 11.251 6.024 0.0051740 DET1 and DDB1 associated 1 LOC100128675 2.648 2.768 3.937 5.762 5.240 5.709 6.027 0.0101002 No description FZD5 6.259 6.182 7.013 8.020 8.853 9.645 6.041 0.0145716 frizzled homolog 5 (Drosophila) FCGBP 2.233 2.233 4.242 5.109 3.686 6.838 6.048 0.0437938 Fc fragment of IgG binding protein ALKBH4 8.856 6.574 7.826 10.610 10.359 10.423 6.048 0.0118693 alkB, alkylation repair homolog 4 (E. coli)) NCRNA00115 1.648 2.234 2.894 4.830 2.739 6.165 6.049 0.0388045 non-protein coding RNA 115 MDM4 6.256 6.545 7.307 9.535 9.150 8.967 6.084 0.0068704 Mdm4 p53 binding protein homolog (mouse) LOC442421 2.648 2.648 2.822 5.929 4.713 5.255 6.091 0.0059123 No description TMEM63A 5.178 4.384 4.935 7.788 7.517 7.461 6.105 0.0029307 transmembrane protein 63A PTBP1 10.547 7.741 8.385 10.997 11.093 10.995 6.113 0.0354769 polypyrimidine tract binding protein 1 C15orf61 6.756 4.734 6.056 8.626 8.769 8.671 6.128 0.0084052 chromosome 15 open reading frame 61 WWTR1 9.083 7.689 8.746 10.062 11.364 12.309 6.140 0.0144718 WW domain containing transcription regulator 1 BEGAIN 5.482 5.815 5.909 7.074 8.623 8.434 6.143 0.0144024 brain-enriched guanylate kinase-associated homolog (rat) ITGB5 11.469 9.747 11.011 14.088 13.589 12.458 6.146 0.0143158 integrin, beta 5 WDR54 4.817 2.800 3.843 7.437 5.701 5.793 6.147 0.0210270 WD repeat domain 54 KCNH3 4.142 3.073 4.160 6.098 6.952 5.696 6.159 0.0119289 potassium voltage-gated channel. subfamily H (eag-related), member 3 PROCA1 0.648 0.648 1.245 3.871 2.987 3.773 6.170 0.0046853 protein interacting with cyclin A1 NONO 8.444 8.711 8.853 11.153 11.774 11.073 6.184 0.0034409 non-POU domain containing, octamer-binding PCBD2 5.998 4.564 4.884 7.513 7.278 7.695 6.185 0.0119490 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 RHOD 5.908 4.674 5.424 7.999 9.507 7.303 6.189 0.0107144 ras homolog gene family, member D SLC26A6 6.368 2.991 5.451 8.082 6.851 8.835 6.194 0.0211650 solute carrier family 26, member 6 FAM3A 6.368 6.729 7.859 10.315 9.360 9.299 6.195 0.0098125 family with sequence similarity 3, member A USF1 2.233 2.233 3.118 5.253 4.818 5.752 6.207 0.0053140 upstream transcription factor 1 RDBP 8.238 7.245 6.419 10.492 9.989 9.054 6.212 0.0151075 RD RNA binding protein SKA1 0.648 0.648 0.648 3.081 3.284 3.773 6.213 0.0022908 spindle and kinetochore associated complex subunit 1 CENPA 0.648 0.648 0.999 3.662 3.284 3.043 6.213 0.0035844 centromere protein A KLRC3 0.648 0.648 1.719 2.202 3.284 5.407 6.213 0.0246402 killer cell lectin-like receptor subfamily C, member 3 LXN 3.194 4.021 2.329 6.124 5.411 5.830 6.218 0.0101362 latexin POP4 3.619 2.233 2.987 6.471 5.626 4.777 6.230 0.0115109 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) RPS6KB2 2.233 3.435 3.592 5.330 6.234 5.045 6.244 0.0134319 ribosomal protein S6 kinase, 70 kDa, polypeptide 2 DNAH12 3.422 3.557 3.645 6.065 6.340 6.091 6.247 0.0017071 dynein, axonemal, heavy chain 12 KAT5 5.982 5.883 3.696 8.625 7.290 6.905 6.249 0.0268690 K(lysine) acetyltransferase 5 DAXX 9.165 7.966 9.083 11.415 11.809 11.438 6.254 0.0048094 death-domain associated protein NRBP1 8.644 8.738 8.507 11.870 11.290 11.138 6.259 0.0022305 nuclear receptor binding protein 1 ACP1 6.062 5.239 6.471 8.709 9.351 7.416 6.266 0.0146520 acid phosphatase 1, soluble GPR137 6.570 5.610 7.392 9.654 9.218 9.150 6.266 0.0074998 G protein-coupled receptor 137 DGKZ 5.973 5.489 5.902 7.877 8.550 8.766 6.268 0.0047733 diacylglycerol kinase, zeta C21 orf2 8.234 4.692 6.995 9.877 9.644 9.054 6.272 0.0203179 chromosome 21 open reading frame 2 CCR7 3.233 5.306 4.835 7.485 5.768 9.409 6.275 0.0207442 chemokine (C-C motif) receptor 7 RIPK1 8.020 6.117 6.060 9.536 9.163 8.710 6.277 0.0184683 receptor (TNFRSF)-interacting serine-threonine kinase 1 FGFRL1 6.350 7.142 7.403 9.000 10.486 9.742 6.277 0.0077972 fibroblast growth factor receptor-like 1 S100 A3 5.264 3.247 3.423 6.308 7.915 5.398 6.280 0.0253244 S100 calcium binding protein A3 DCFS 6.232 2.625 4.839 7.890 7.493 6.634 6.294 0.0246069 decapping enzyme, scavenger C4orf52 1.648 1.648 2.307 4.376 4.017 4.961 6.295 0.0059213 chromosome 4 open reading frame 52 SLC13A3 2.648 3.520 2.744 5.385 5.733 5.400 6.303 0.0053501 solute carrier family 13 (sodium-dependent dicarboxylate transporter), members NUDT16 4.264 4.280 3.574 7.404 6.234 6.388 6.321 0.0072697 nudix (nucleoside diphosphate linked moiety X)-type motif 16 SRRT 8.801 8.070 9.600 11.344 11.756 11.464 6.335 0.0070742 serrate RNA effector molecule homolog (Arabidopsis) PCYOX1 7.113 4.762 4.280 7.817 7.427 7.309 6.345 0.0378818 prenylcysteine oxidase 1 PLIN5 4.620 3.402 4.816 6.509 7.483 6.832 6.350 0.0090846 perilipin 5 FST 9.636 8.987 10.029 12.696 12.461 10.747 6.352 0.0180815 follistatin SNRNP25 5.550 2.714 3.644 6.312 6.666 6.058 6.358 0.0257397 small nuclear ribonucleoprotein 25 kDa (U11/U12) REL 9.044 7.696 7.864 10.630 10.254 11.714 6.362 0.0111477 v-rel reticuloendotheliosis viral oncogene homolog (avian) COPS7B 3.422 2.926 3.423 6.136 4.692 6.091 6.363 0.0127830 COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) THAP4 8.737 7.168 7.951 10.624 10.715 10.029 6.375 0.0108045 THAP domain containing 4 MDK 9.419 6.573 7.942 9.393 10.615 10.915 6.378 0.0318180 midkine (neurite growth-promoting factor 2) LDLR 11.145 9.238 10.343 13.139 13.351 11.911 6.381 0.0158922 low density lipoprotein receptor CYP27C1 5.264 4.451 5.124 7.829 7.659 7.799 6.385 0.0025702 cytochrome P450, family 27, subfamily C, polypeptide 1 STEAP1 6.202 5.166 5.748 9.886 8.423 7.786 6.390 0.0086742 six transmembrane epithelial antigen of the prostate 1 B3GAT3 7.312 5.769 6.057 9.021 9.183 8.448 6.404 0.0113251 beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase l) DNAJC8 7.894 7.702 8.770 10.961 10.573 10.505 6.404 0.0062901 DnaJ (Hsp40) homolog, subfamily C, member 8 C6orf145 10.253 9.976 11.077 13.185 12.581 13.758 6.416 0.0069452 chromosome 6 open reading frame 145 HMOX2 8.521 6.826 8.220 10.903 11.025 10.098 6.423 0.0086991 heme oxygenase (decycling) 2 DPH3B 1.648 1.834 1.689 4.376 4.811 4.104 6.437 0.0026367 No description NEDD4 2.648 2.908 3.405 5.599 5.682 5.336 6.443 0.0041515 neural precursor cell expressed, developmentally down- regulated 4 ZBTB7C 6.547 3.475 2.721 5.409 7.084 7.657 6.446 0.0484676 zinc finger and BTB domain containing 7C WDR45 8.195 7.305 8.012 10.884 10.370 10.278 6.448 0.0046672 WD repeat domain 45 KREMEN1 4.916 5.052 5.621 7.734 7.746 7.887 6.468 0.0034874 kringle containing transmembrane protein 1 CARS 8.256 7.492 8.359 11.053 10.980 9.389 6.469 0.0151664 cysteinyl-tRNA synthetase GSC 5.781 4.027 5.796 8.490 7.162 8.178 6.472 0.0125813 goosecoid homeobox NXNL2 3.619 3.415 4.290 6.628 6.168 6.313 6.472 0.0047192 nucleoredoxin-like 2 YPEL1 4.214 4.997 5.011 7.002 7.707 7.358 6.480 0.0052600 yippee-like 1 (Drosophila) MAP3K7IP1 6.368 4.543 5.200 8.611 7.967 7.239 6.480 0.0143435 No description UGGT2 4.565 3.752 5.288 7.985 7.353 5.802 6.485 0.0193924 UDP-glucose glycoprotein glucosyltransferase 2 TOM1 7.660 7.549 5.875 10.358 8.711 8.977 6.488 0.0242513 target of myb1 (chicken) KIAA0649 5.644 3.143 3.231 6.384 6.386 5.842 6.494 0.0318360 KIAA0649 SNORA80B 0.648 2.359 0.648 3.871 4.728 3.351 6.508 0.0119581 small nucleolar RNA, H/ACA box 80B KRTAP2-4 0.648 0.648 0.648 2.202 4.602 3.351 6.508 0.0122659 keratin associated protein 2-4 DUSP9 3.194 0.648 0.648 3.351 4.043 3.773 6.508 0.0323712 dual specificity phosphatase 9 PRDX6 10.697 10.443 10.454 13.734 12.822 13.162 6.534 0.0035934 peroxiredoxin 6 S100A13 0.648 0.648 1.719 3.351 4.428 4.389 6.540 0.0045827 S100 calcium binding protein A13 AHNAK2 5.322 3.737 3.982 5.462 6.785 8.036 6.561 0.0262409 AHNAK nucleoprotein 2 PYCR1 8.229 5.885 7.535 10.249 10.373 8.817 6.563 0.0198589 pyrroline-5-carboxylate reductase 1 YIF1B 2.648 3.337 3.381 5.904 6.229 5.367 6.581 0.0046312 Yip interacting factor homolog B (S. cerevisiae) CTRC 5.109 2.233 3.008 4.953 6.218 5.811 6.586 0.0368662 chymotrypsin C (caldecrin) ADRB3 4.972 4.986 4.665 7.695 7.380 7.786 6.605 0.0017432 adrenergic, beta-3-, receptor IQCE 5.453 3.951 4.219 6.943 7.048 6.937 6.607 0.0108565 IQ motif containing E PIK3CG 1.648 1.648 1.648 4.376 4.421 4.376 6.623 0.0006645 phosphoinositide-3-kinase, catalytic, gamma polypeptide FADS6 1.648 1.648 1.834 4.376 4.529 4.493 6.623 0.0009321 fatty acid desaturase domain family, member 6 ERP27 1.648 1.648 1.834 4.931 4.174 4.376 6.623 0.0024801 endoplasmic reticulum protein 27 SIRPB1 4.423 1.648 1.834 4.376 5.120 5.289 6.623 0.0331643 signal-regulatory protein beta 1 HNRNPU 9.462 9.673 10.173 12.191 12.604 12.776 6.628 0.0032080 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) ATP6VOB 8.664 8.998 9.078 12.068 11.360 11.727 6.634 0.0024530 ATPase, H+ transporting, lysosomal 21 kDa, VO subunit b FANCC 4.482 3.921 5.457 6.652 7.841 8.150 6.639 0.0083241 Fanconi anemia, complementation group C SNX8 5.644 6.180 7.334 9.368 9.074 8.375 6.643 0.0121487 sorting nexin 8 MMP17 2.970 3.682 5.146 6.742 6.169 6.414 6.647 0.0154263 matrix metallopeptidase 17 (membrane-inserted) LOC100128640 2.648 3.314 3.891 6.049 5.682 6.251 6.659 0.0055879 No description SCARF1 4.378 2.970 3.607 5.706 6.345 6.414 6.661 0.0098395 scavenger receptor class F, member 1 REEP4 5.644 4.206 5.452 8.191 8.224 7.604 6.678 0.0056198 receptor accessory protein 4 MMEL1 1.648 1.648 2.721 4.721 5.463 3.929 6.689 0.0097120 membrane metallo-endopeptidase-like 1 NAP1L4 9.539 8.476 10.753 11.936 12.636 12.290 6.732 0.0127199 nucleosome assembly protein 1 -like 4 SETDB1 3.947 4.681 5.606 7.499 7.434 6.857 6.738 0.0110374 SET domain, bifurcated 1 TBRG4 7.002 7.572 8.748 10.736 10.847 9.756 6.745 0.0113106 transforming growth factor beta regulator 4 C7orf43 5.690 6.907 6.059 8.601 8.817 8.925 6.763 0.0066700 chromosome 7 open reading frame 43 PRRT1 5.861 2.648 3.533 6.131 6.291 6.955 6.768 0.0296343 proline-rich transmembrane protein 1 ARL16 7.672 6.908 7.938 9.918 10.698 9.757 6.770 0.0072426 ADP-ribosylation factor-like 16 TMEM212 6.190 5.826 6.188 8.496 8.947 9.601 6.773 0.0030478 transmembrane protein 212 RRP7B 3.792 3.630 3.953 5.420 6.951 6.553 6.779 0.0096960 ribosomal RNA processing 7 homolog B (S. cerevisiae) SNX22 4.672 5.305 5.648 7.542 7.842 8.412 6.793 0.0051969 sorting nexin 22 NLE1 7.085 5.988 6.730 8.941 9.911 8.752 6.796 0.0087920 notchless homolog 1 (Drosophila) SFRS14 5.861 5.074 5.572 7.924 8.626 8.069 6.799 0.0041244 No description PKP4 8.857 7.861 8.549 10.628 11.874 10.654 6.810 0.0089244 plakophilin 4 DDX39 8.965 8.184 9.528 11.733 11.388 12.062 6.811 0.0051879 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 RPS11 14.938 13.319 13.651 16.805 16.567 16.087 6.813 0.0114645 ribosomal protein S11 SLC43A2 7.746 6.791 6.328 9.838 9.135 9.561 6.819 0.0089154 solute carrier family 43, member 2 NHLRC1 2.233 2.233 2.565 5.003 5.183 5.279 6.819 0.0012468 NHL repeat containing 1 ATP2A3 5.731 5.050 4.995 8.448 7.765 8.258 6.822 0.0028517 ATPase, Ca++ transporting, ubiquitous TMEM229B 1.648 1.648 1.648 5.102 4.421 3.294 6.832 0.0096780 transmembrane protein 229B LOC344967 7.478 5.748 6.198 8.789 9.086 8.970 6.833 0.0119199 No description PATE4 0.648 4.713 2.781 5.553 5.742 5.343 6.835 0.0253334 prostate and testis expressed 4 KIAA1984 1.648 2.625 3.963 4.830 5.932 5.398 6.837 0.0153480 KIAA1984 FLJ25006 2.233 3.047 3.323 5.821 5.167 6.074 6.842 0.0051061 No description POLG 8.151 8.133 8.700 10.906 10.926 11.497 6.845 0.0029848 polymerase (DNA directed), gamma TMEM222 8.159 7.523 7.573 10.934 10.769 10.196 6.845 0.0028177 transmembrane protein 222 FKBPL 5.452 3.294 3.077 5.853 6.401 6.962 6.849 0.0223407 FK506 binding protein like APEH 8.083 5.618 7.093 10.272 9.872 9.040 6.861 0.0142818 N-acylaminoacyl-peptide hydrolase SLC35B1 7.886 7.192 8.196 11.478 10.665 9.658 6.864 0.0085598 solute carrier family 35, member B1 APEX2 6.232 3.627 5.060 8.120 7.843 6.743 6.882 0.0201300 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 MUC16 3.233 3.848 3.233 5.157 7.664 6.016 6.883 0.0124530 mucin 16, cell surface associated TMEM81 0.648 1.078 1.719 2.714 3.871 5.462 6.931 0.0144898 transmembrane protein 81 NDUFV3 7.470 5.950 6.313 10.267 10.042 8.457 6.947 0.0094257 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10 kDa DDN 1.648 1.648 2.177 3.326 4.529 4.975 6.953 0.0122270 dendrin PSMB2 8.737 9.104 8.911 11.987 11.709 10.520 6.953 0.0100371 proteasome (prosome, macropain) subunit, beta type, 2 SCFD2 2.970 3.984 3.111 5.859 5.910 6.111 6.957 0.0052149 sed family domain containing 2 KIAA1949 12.647 9.975 9.867 12.774 12.769 14.106 6.961 0.0329334 KIAA1949 B3GNT3 4.620 4.199 4.939 7.195 7.419 7.528 6.963 0.0024170 UDP-GlcNAc:betaGal beta-1,3-N- acetylglucosaminyltransferase 3 STAT4 6.196 3.047 3.278 6.451 5.858 8.147 7.016 0.0330562 signal transducer and activator of transcription 4 PSPH 4.817 2.233 2.233 5.551 5.637 5.045 7.022 0.0291553 phosphoserine phosphatase C18orf25 6.447 6.066 5.995 8.630 8.880 9.268 7.034 0.0025868 chromosome 18 open reading frame 25 TRIP4 5.739 4.335 4.593 8.513 7.921 7.156 7.066 0.0067213 thyroid hormone receptor interactor 4 CDH24 4.142 2.565 4.481 6.423 7.300 6.965 7.077 0.0059754 cadherin 24, type 2 CD40 7.982 7.023 5.479 10.433 9.314 9.847 7.081 0.0106402 CD40 molecule, TNF receptor superfamily member 5 KIAA0406 4.264 4.887 3.431 7.089 7.477 6.897 7.086 0.0045147 No description APOL3 7.218 5.220 6.824 10.044 9.074 8.877 7.087 0.0103102 apolipoprotein L, 3 METT11D1 7.715 6.688 7.373 10.253 10.378 9.514 7.090 0.0050159 methyltransferase 11 domain containing 1 DHX38 7.942 6.174 5.515 9.761 8.342 10.121 7.094 0.0158146 DEAH (Asp-Glu-Ala-His) box polypeptide 38 ADORA3 1.648 1.648 1.689 4.477 3.499 4.830 7.106 0.0067664 adenosine A3 receptor FLJ14107 1.648 1.648 1.648 4.477 4.945 3.294 7.106 0.0091740 No description PLD6 5.393 4.174 4.155 6.984 7.003 7.285 7.107 0.0083782 phospholipase D family, member 6 CAPZB 11.147 9.276 10.071 13.734 12.906 12.597 7.131 0.0084974 capping protein (actin filament) muscle Z-line, beta YJEFN3 1.648 2.625 2.559 5.042 4.692 5.459 7.132 0.0046763 YjeF N-terminal domain containing 3 KLC1 8.922 7.998 9.869 11.798 11.759 11.041 7.145 0.0116440 kinesin light chain 1 DNHD1 5.455 4.625 5.180 8.293 7.574 7.738 7.151 0.0037868 dynein heavy chain domain 1 PIK3R1 8.455 7.701 7.359 11.299 10.710 10.014 7.178 0.0062672 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) FAM70B 4.972 0.648 2.401 5.870 5.246 4.748 7.182 0.0377764 family with sequence similarity 70, member B CXCL17 1.648 4.006 3.879 5.908 6.914 4.493 7.184 0.0267005 chemokine (C-X-C motif) ligand 17 TTC21A 0.648 0.648 1.753 3.081 4.043 4.602 7.201 0.0074818 tetratricopeptide repeat domain 21A LOC644669 0.648 3.043 4.647 5.813 5.894 6.847 7.214 0.0149459 No description ERLIN1 8.037 5.870 8.277 10.934 10.519 10.889 7.223 0.0063491 ER lipid raft associated 1 FAM41C 5.264 4.386 6.217 7.786 8.549 8.125 7.266 0.0076440 family with sequence similarity 41, member C MTERFD2 4.086 4.627 4.371 7.748 6.948 7.008 7.269 0.0028426 MTERF domain containing 2 OSBPL7 5.350 3.607 4.872 7.068 6.966 8.217 7.295 0.0104017 oxysterol binding protein-like 7 PAPL 7.567 6.920 8.019 10.436 10.341 10.823 7.304 0.0026548 No description SP9 3.194 1.477 3.431 4.854 4.602 6.304 7.324 0.0193334 Sp9 transcription factor homolog (mouse) KCNE1L 0.648 0.648 1.387 2.202 4.043 4.262 7.338 0.0146374 KCNE1-like SPHK2 6.062 5.012 6.053 8.941 8.458 8.437 7.356 0.0038458 sphingosine kinase 2 C6orf120 7.113 5.357 5.772 8.591 8.672 8.653 7.364 0.0107594 chromosome 6 open reading frame 120 THPO 1.648 2.121 2.934 5.314 4.529 5.220 7.367 0.0058492 thrombopoietin TYMP 9.517 9.168 9.502 14.060 12.216 12.052 7.378 0.0045466 thymidine phosphorylase GYS1 5.645 6.278 7.827 10.155 9.466 8.529 7.379 0.0141425 glycogen synthase 1 (muscle) METTL2A 4.972 5.204 4.346 7.339 7.862 7.984 7.415 0.0031068 methyltransferase like 2A CKB 9.440 8.053 9.757 11.045 12.336 12.605 7.443 0.0103192 creatine kinase, brain IL1B 6.692 5.495 5.319 8.393 6.688 9.915 7.454 0.0294596 interleukin 1, beta HAX1 8.278 7.288 7.243 10.387 10.458 10.142 7.460 0.0046132 HCLS1 associated protein X-1 CTU2 5.814 5.405 6.103 8.593 9.006 8.388 7.477 0.0023539 cytosolic thiouridylase subunit 2 homolog (S. pombe) CROCCL1 5.552 5.406 3.427 8.457 7.365 8.208 7.492 0.0077140 No description GPRIN1 1.648 3.230 4.038 6.136 6.149 5.997 7.495 0.0075539 G protein regulated inducer of neurite outgrowth 1 ZFAND2B 4.525 4.876 5.818 7.871 7.433 7.803 7.508 0.0067484 zinc finger, AN1-type domain 2B KCNG2 0.648 3.043 1.387 4.854 5.964 2.370 7.570 0.0333508 potassium voltage-gated channel, subfamily G, member 2 FAM153B 4.008 4.536 4.275 7.078 7.385 7.198 7.581 0.0011130 family with sequence similarity 153, member B SNX5 7.631 6.632 7.519 10.177 10.555 10.412 7.585 0.0019983 sorting nexin 5 STX1A 3.947 4.735 5.847 6.872 8.115 7.944 7.595 0.0108898 syntaxin 1A (brain) PLXNB1 6.814 6.921 7.470 9.847 10.753 9.132 7.600 0.0065619 plexin B1 ZBTB5 4.969 4.139 5.165 7.740 7.341 8.091 7.601 0.0033799 zinc finger and BTB domain containing 5 C9orf142 4.972 3.810 5.246 7.899 8.131 7.581 7.604 0.0032350 chromosome 9 open reading frame 142 C2orf52 0.648 2.758 3.143 5.764 5.687 4.748 7.612 0.0093362 chromosome 2 open reading frame 52 FLVCR1 2.970 4.397 3.247 5.899 6.988 6.973 7.615 0.0053917 feline leukemia virus subgroup C cellular receptor 1 C5orf44 3.619 3.467 4.530 6.868 6.398 7.389 7.624 0.0038728 chromosome 5 open reading frame 44 ANKRD36BL1 2.233 3.197 2.917 5.167 5.772 6.785 7.640 0.0047913 No description SLC37A1 5.499 4.230 6.012 8.366 8.795 8.433 7.641 0.0036898 solute carrier family 37 (glycerol-3-phosphate transporter), member 1 PPM1D 5.731 4.688 4.092 7.233 7.036 8.780 7.697 0.0115269 protein phosphatase, Mg2+/Mn2+ dependent, 1D GFER 6.532 5.316 5.634 8.974 8.262 8.598 7.703 0.0053231 growth factor, augmenter of liver regeneration SFRS8 7.087 7.993 7.126 10.072 10.057 10.128 7.706 0.0040128 No description TMOD1 5.087 5.019 5.577 9.015 8.034 6.676 7.711 0.0134693 tropomodulin 1 C17or55 2.648 2.744 3.464 5.755 3.739 6.416 7.738 0.0262638 chromosome 17 open reading frame 55 LOC100288730 3.619 2.649 3.415 6.368 5.968 6.454 7.743 0.0022638 No description RAB3A 6.777 4.033 2.968 6.368 6.987 8.578 7.746 0.0345411 RAB3A, member RAS oncogene family NES 9.415 7.737 9.196 10.545 12.372 12.346 7.762 0.0114825 nestin HLA-DOB 1.648 1.648 1.689 4.477 5.120 4.607 7.772 0.0009820 major histocompatibility complex, class II, DO beta ANKRD45 3.619 2.233 2.814 5.873 5.583 5.774 7.784 0.0045979 ankyrin repeat domain 45 RBBP9 4.008 3.420 4.975 6.981 7.625 6.818 7.853 0.0051289 retinoblastoma binding protein 9 NLRX1 5.264 1.648 2.281 5.997 5.256 4.975 7.864 0.0433314 NLR family member X1 LETM2 1.648 2.064 3.296 4.624 5.304 5.398 7.867 0.0081605 leucine zipper-EF-hand containing transmembrane protein 2 ABHD8 6.495 3.346 4.343 8.018 7.324 7.036 7.896 0.0209092 abhydrolase domain containing 8 FAM115A 7.304 6.611 7.445 9.526 10.287 10.692 7.903 0.0035574 family with sequence similarity 115, member A IL2RA 6.912 5.961 6.748 9.450 9.394 9.895 7.909 0.0022998 interleukin 2 receptor, alpha KIAA1919 4.734 1.978 3.814 6.619 6.934 6.798 7.910 0.0081043 KIAA1919 DNAI2 0.648 0.648 1.387 3.351 3.633 7.721 7.917 0.0120939 dynein, axonemal, intermediate chain 2 SDS 0.648 3.644 2.781 4.748 3.633 7.410 7.917 0.0327518 serine dehydratase SLFN13 3.818 4.230 4.905 7.222 7.204 7.619 7.958 0.0025161 schlafen family member 13 WAS 1.648 3.294 2.566 4.725 4.641 7.281 7.962 0.0150742 Wiskott-Aldrich syndrome (eczema-thrombocytopenia) ANKRD11 7.704 7.824 8.703 10.699 11.042 10.892 7.973 0.0037078 ankyrin repeat domain 11 CCDC61 2.233 2.461 3.291 6.288 5.513 4.777 7.983 0.0070381 coiled-coil domain containing 61 GOLGA2L1 3.456 3.733 3.957 6.732 5.272 7.050 7.991 0.0105584 No description EEF1A2 2.970 3.866 5.042 7.698 8.042 5.847 7.999 0.0105854 eukaryotic translation elongation factor 1 alpha 2 C21 orf88 6.791 6.388 6.747 9.443 9.571 9.798 8.040 0.0010270 chromosome 21 open reading frame 88 MRPL41 7.081 6.036 8.507 10.191 10.088 9.294 8.041 0.0158832 mitochondrial ribosomal protein L41 C14orf73 1.648 1.978 2.450 4.624 5.102 5.459 8.051 0.0023990 chromosome 14 open reading frame 73 LAMC3 7.714 6.902 7.620 9.912 10.480 11.681 8.052 0.0041785 laminin, gamma 3 LRRC27 6.541 5.659 6.734 9.093 9.552 9.694 8.061 0.0024350 leucine rich repeat containing 27 ZSCAN20 0.648 0.648 0.729 3.662 4.043 3.351 8.074 0.0011296 zinc finger and SCAN domain containing 20 INVS 0.648 0.648 0.999 3.662 3.633 4.389 8.074 0.0013910 inversin DUOX2 0.648 1.753 1.564 3.662 6.202 4.389 8.074 0.0069750 dual oxidase 2 SMCR8 6.777 6.139 6.769 9.791 9.170 9.778 8.079 0.0020073 Smith-Magenis syndrome chromosome region, candidate 8 SETD8 8.182 7.579 8.961 10.750 11.199 11.345 8.095 0.0050250 SET domain containing (lysine methyltransferase) 8 C9orf41 5.076 3.397 5.123 7.189 7.492 8.146 8.129 0.0066790 chromosome 9 open reading frame 41 C6orf129 0.648 4.529 5.996 8.084 7.554 6.777 8.139 0.0196392 chromosome 6 open reading frame 129 TCP11L1 5.899 5.671 5.478 8.933 8.699 8.210 8.160 0.0018388 t-complex 11 (mouse)-like 1 ZFP41 4.525 2.951 3.815 7.076 6.851 6.613 8.201 0.0039359 zinc finger protein 41 homolog (mouse) DAK 7.283 4.583 5.159 8.196 8.724 7.769 8.208 0.0213536 dihydroxyacetone kinase 2 homolog (S. cerevisiae) GGT8P 3.860 0.648 1.564 4.972 3.871 4.602 8.213 0.0299712 gamma-glutamyltransferase 8 pseudogene ZWILCH 3.422 1.648 2.177 6.340 4.692 5.416 8.245 0.0081834 Zwilch, kinetochore associated, homolog (Drosophila) GDH 8.090 5.458 6.036 9.171 8.740 9.082 8.260 0.0215393 GDP dissociation inhibitor 1 MCOLN2 6.158 4.550 5.795 7.600 7.930 9.399 8.280 0.0123019 mucolipin 2 BRF1 6.753 4.951 6.415 9.468 9.306 9.615 8.297 0.0031851 BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) TIMM17B 5.452 5.056 5.783 8.892 8.507 8.094 8.307 0.0019712 translocase of inner mitochondrial membrane 17 homolog B (yeast) TNFRSF1B 9.518 7.432 9.619 12.188 12.396 12.674 8.308 0.0043650 tumor necrosis factor receptor superfamily, member 1B FGFR2 5.961 5.886 6.302 8.472 9.018 9.473 8.323 0.0026998 fibroblast growth factor receptor 2 PTPRCAP 4.314 3.452 5.196 6.947 6.510 8.362 8.327 0.0106964 protein tyrosine phosphatase, receptor type, C-associated protein MYOM1 3.792 2.648 3.202 5.072 6.264 7.014 8.354 0.0089584 myomesin 1, 185 kDa ZNF425 6.741 4.904 5.334 8.399 8.346 8.736 8.365 0.0079137 zinc finger protein 425 G20orf4 2.233 6.023 5.771 8.836 8.958 8.289 8.367 0.0086076 chromosome 20 open reading frame 4 ZNF222 0.648 3.959 1.245 4.632 4.311 3.773 8.372 0.0398055 zinc finger protein 222 ANKFY1 7.155 5.147 5.861 9.208 8.931 8.746 8.397 0.0078291 ankyrin repeat and FYVE domain containing 1 NHLH1 1.648 2.304 2.625 4.721 5.730 5.220 8.411 0.0033709 nescient helix loop helix 1 C3orf42 2.648 3.659 5.385 5.982 6.731 6.955 8.412 0.0182250 chromosome 3 open reading frame 42 MAGI2 4.826 4.767 5.412 8.108 7.842 8.273 8.430 0.0012828 membrane associated guanylate kinase, WW and PDZ domain containing 2 KPTN 6.232 4.529 6.036 8.246 9.047 9.310 8.442 0.0049203 kaptin (actin binding protein) LOC100216545 4.525 2.794 4.076 7.156 6.580 7.592 8.454 0.0041695 No description IRF3 5.849 4.352 4.842 7.922 7.805 7.986 8.456 0.0048752 interferon regulatory factor 3 GZF1 5.173 3.691 5.685 8.257 8.123 8.562 8.479 0.0035484 GDNF-inducible zinc finger protein 1 MAK 2.648 2.648 2.822 5.929 5.733 5.558 8.485 0.0006825 male germ cell-associated kinase CLDN4 7.271 5.575 4.127 8.870 8.665 8.029 8.517 0.0168496 claudin 4 SCN4A 4.872 4.214 7.282 7.966 7.961 8.549 8.539 0.0207962 sodium channel, voltage-gated, type IV, alpha subunit STEAP3 2.648 2.970 3.464 6.066 8.015 5.682 8.550 0.0048184 STEAP family member 3 TCEA2 6.896 5.783 6.622 9.370 9.273 9.995 8.567 0.0028607 transcription elongation factor A (SH), 2 PARP10 7.070 4.346 6.639 9.474 9.291 10.176 8.610 0.0062312 poly (ADP-ribose) polymerase family, member 10 C11 orf84 6.777 5.856 6.900 9.887 8.218 11.028 8.633 0.0104489 chromosome 11 open reading frame 84 ZNF554 4.708 4.194 5.145 7.837 7.680 7.822 8.660 0.0015629 zinc finger protein 554 RPS19BP1 6.340 4.529 4.477 8.800 8.921 7.592 8.664 0.0063671 ribosomal protein S19 binding protein 1 CCBP2 4.793 5.167 6.076 8.150 8.516 8.283 8.668 0.0035664 chemokine binding protein 2 SLC39A13 8.757 7.078 7.746 10.866 11.134 10.658 8.693 0.0048364 solute carrier family 39 (zinc transporter), member 13 INHA 0.648 0.648 0.648 5.514 3.633 3.773 8.720 0.0024981 inhibin, alpha LOC729799 0.648 0.648 0.729 5.035 3.284 3.773 8.720 0.0030839 No description PAK6 0.648 2.941 3.046 5.256 7.339 3.773 8.720 0.0197452 p21 protein (Cdc42/Rac)-activated kinase 6 BIRC5 2.233 2.233 2.702 3.535 5.360 5.963 8.736 0.0168225 baculoviral lAP repeat-containing 5 DDX51 5.872 5.211 5.829 8.806 8.999 8.719 8.739 0.0008905 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 C20orf200 0.648 2.758 4.314 6.177 5.742 5.889 8.756 0.0124010 chromosome 20 open reading frame 200 USP45 5.289 4.323 4.492 7.626 7.575 8.418 8.773 0.0025341 ubiquitin specific peptidase 45 CHTF18 6.732 4.737 5.543 8.201 8.682 9.830 8.807 0.0074728 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) TAF1C 5.264 5.956 7.390 9.099 9.039 9.249 8.834 0.0080863 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110 kDa LMAN2L 7.001 4.760 6.052 9.002 9.259 9.195 8.835 0.0057397 lectin, mannose-binding 2-like RNF217 1.648 2.675 2.234 3.557 5.818 5.802 8.837 0.0131179 ring finger protein 217 HSPB1 6.756 4.351 8.610 8.659 9.355 11.755 8.846 0.0248863 heat shock 27 kDa protein 1 LRG1 5.781 2.894 5.736 5.781 8.928 8.889 8.863 0.0273480 leucine-rich alpha-2-glycoprotein 1 GPATCH3 4.525 4.616 6.703 8.229 8.067 7.677 8.889 0.0137778 G patch domain containing 3 NCOR2 7.864 7.048 6.689 10.378 9.842 10.740 8.893 0.0032260 nuclear receptor corepressor 2 MXD3 4.826 3.111 4.508 7.452 7.989 7.238 8.956 0.0033439 MAX dimerization protein 3 KIAA0562 6.457 5.507 6.000 9.174 9.235 8.823 9.027 0.0017730 KIAA0562 PPP4R1L 1.648 1.648 1.648 5.272 4.811 4.830 9.075 0.0004614 protein phosphatase 4, regulatory subunit 1 -like CHMP6 5.598 3.643 5.167 8.647 8.351 7.198 9.092 0.0068884 chromatin modifying protein 6 PAPPA 7.069 8.327 7.074 12.144 10.259 9.656 9.092 0.0100461 pregnancy-associated plasma protein A, pappalysin 1 MYLPF 0.648 2.593 1.564 4.748 5.742 4.262 9.093 0.0058402 myosin light chain, phosphorylatable, fast skeletal muscle LRWD1 3.619 4.457 4.214 7.405 7.417 6.910 9.129 0.0015719 leucine-rich repeats and WD repeat domain containing 1 CIB2 7.101 3.107 5.624 8.818 8.641 9.442 9.150 0.0109764 calcium and integrin binding family member 2 CSNK2A1P 7.568 6.006 7.283 10.480 10.663 10.240 9.169 0.0020343 casein kinase 2, alpha 1 polypeptide pseudogene DHX8 6.520 4.282 6.262 9.253 9.718 9.386 9.173 0.0032863 DEAH (Asp-Glu-Ala-His) box polypeptide 8 DCLRE1C 5.482 4.472 4.501 8.172 7.670 8.184 9.179 0.0020932 DNA cross-link repair 1C PBX4 6.710 4.969 5.291 9.519 7.434 9.911 9.196 0.0104849 pre-B-cell leukemia homeobox 4 LOC146880 2.233 2.565 4.335 5.778 6.469 5.561 9.273 0.0105029 No description SDR39U1 7.893 7.755 8.570 11.201 10.968 11.469 9.276 0.0015130 short chain dehydrogenase/reductase family 39U, member 1 LOC401127 4.142 3.047 3.720 6.288 6.368 7.357 9.286 0.0041965 No description TAF3 7.298 5.721 5.444 8.956 8.676 8.936 9.287 0.0101633 TAF3 RNA polymerase II, TATA box binding protein (TBP)- associated factor, 140 kDa ZGPAT 5.173 2.822 4.083 7.302 7.151 7.312 9.312 0.0061224 zinc finger, CCCH-type with G patch domain TGFB111 10.251 7.018 9.260 12.662 12.481 11.581 9.324 0.0108225 transforming growth factor beta 1 induced transcript 1 GMFG 5.264 1.648 5.903 9.069 7.759 8.486 9.327 0.0095733 glia maturation factor, gamma HPVC1 0.648 0.648 0.729 3.871 3.871 4.262 9.332 0.0004163 human papillomavirus (type 18) E5 central sequence-like 1 SLC16A13 0.648 0.648 0.648 3.871 4.311 3.351 9.332 0.0011837 solute carrier family 16, member 13 (monocarboxylic acid transporter 13) SPC25 0.648 0.648 0.729 3.871 3.284 4.602 9.332 0.0019622 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) CYP2D6 0.648 0.648 0.729 4.021 3.871 3.043 9.332 0.0023179 cytochrome P450, family 2, subfamily D, polypeptide 6 TDGF1 0.648 0.648 0.648 3.871 5.053 3.351 9.332 0.0023719 teratocarcinoma-derived growth factor 1 C19or77 0.648 0.648 1.245 3.871 4.728 3.351 9.332 0.0033348 chromosome 19 open reading frame 77 RDH16 0.648 0.648 0.648 4.854 3.871 3.043 9.332 0.0034693 retinol dehydrogenase 16 (all-trans) SYNGR3 0.648 1.649 2.268 3.871 4.043 5.728 9.332 0.0099026 synaptogyrin 3 FERMT1 0.648 0.648 0.648 3.871 6.792 2.370 9.332 0.0130263 fermitin family member 1 ZBTB32 0.648 0.648 1.477 2.202 3.871 5.014 9.332 0.0162402 zinc finger and BTB domain containing 32 UGT2B10 0.648 0.648 0.648 4.021 3.871 0.648 9.332 0.0484340 UDP glucuronosyltransferase 2 family, polypeptide B10 CBS 5.173 4.713 2.841 7.963 8.396 5.793 9.333 0.0156045 cystathionine-beta-synthase S100A7 0.648 4.043 5.396 7.272 8.119 6.684 9.377 0.0128551 S100 calcium binding protein A7 SULT1A4 4.972 6.308 6.711 8.484 9.543 9.678 9.416 0.0054818 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 RASSF4 6.368 3.966 6.121 9.131 8.684 9.603 9.416 0.0048842 Ras association (RalGDS/AF-6) domain family member 4 PHB 4.423 3.832 3.294 6.532 7.717 6.685 9.430 0.0039449 prohibitin PRRG2 1.648 3.247 4.429 5.502 6.934 6.486 9.439 0.0109993 proline rich Gla (G-carboxyglutamic acid) 2 SPPL2B 7.572 5.453 7.312 10.267 10.562 10.734 9.516 0.0029667 No description FBXO27 6.003 4.242 5.287 8.163 8.540 8.622 9.533 0.0036357 F-box protein 27 VMO1 0.648 1.477 3.046 6.031 3.871 6.304 9.571 0.0083331 vitelline membrane outer layer 1 homolog (chicken) PANK4 6.818 6.439 8.490 9.851 10.120 10.084 9.619 0.0104399 pantothenate kinase 4 CYB5R2 5.377 5.206 6.429 9.436 9.682 8.478 9.659 0.0022076 cytochrome b5 reductase 2 KAT2A 6.838 6.777 7.714 10.112 9.978 10.991 9.672 0.0025612 K(lysine) acetyltransferase 2A RBM19 6.067 5.591 6.470 9.341 9.672 8.961 9.676 0.0013549 RNA binding motif protein 19 B3GAT1 2.233 2.233 2.233 3.737 7.279 5.509 9.688 0.0124620 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) KDM5C 7.234 5.985 6.462 9.747 9.813 9.729 9.747 0.0019532 lysine (K)-specific demethylase 5C HIP1R 7.086 5.948 7.588 9.144 11.134 10.375 9.771 0.0063851 huntingtin interacting protein 1 related TMCO7 2.970 3.572 4.173 6.882 6.872 6.701 9.849 0.0016711 transmembrane and coiled-coil domains 7 AKNA 8.629 6.813 9.566 11.545 11.930 12.585 9.856 0.0054638 AT-hook transcription factor SLC14A1 5.552 4.555 6.208 8.024 8.855 8.870 9.870 0.0047102 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) C21 orf99 0.648 0.648 0.999 4.021 4.311 3.351 9.932 0.0016891 No description MRPS18C 1.648 5.203 3.517 7.353 6.831 6.394 9.946 0.0117362 mitochondrial ribosomal protein S18C C5orf60 0.648 0.648 0.729 5.133 3.871 3.966 9.973 0.0009640 chromosome 5 open reading frame 60 MTMR15 2.233 2.233 2.932 5.551 6.428 5.147 9.973 0.0026728 No description LRCH4 7.300 5.815 7.845 10.106 10.621 10.772 9.994 0.0036177 leucine-rich repeats and calponin homology (CH) domain containing 4 SLC25A1 7.796 6.246 6.749 10.487 10.212 9.570 10.008 0.0042700 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 PTPN6 5.861 3.104 3.802 6.429 7.126 7.789 10.017 0.0161737 protein tyrosine phosphatase, non-receptor type 6 TMEM169 1.648 1.648 1.834 5.409 4.017 4.975 10.033 0.0031941 transmembrane protein 169 MPHOSPH6 4.525 5.812 5.717 8.400 9.149 8.002 10.102 0.0042520 M-phase phosphoprotein 6 KLC2 6.721 5.450 7.174 10.058 10.155 9.832 10.107 0.0020662 kinesin light chain 2 GATS 6.569 2.970 3.410 7.952 6.313 7.546 10.147 0.0243061 GATS, stromal antigen 3 opposite strand CSF3R 2.233 2.233 3.073 4.715 5.583 7.787 10.198 0.0083692 colony stimulating factor 3 receptor (granulocyte) ADC 5.322 5.045 5.646 7.264 8.695 9.009 10.290 0.0062042 arginine decarboxylase IL1RL1 6.639 8.888 8.061 11.426 11.751 11.112 10.303 0.0037958 interleukin 1 receptor-like 1 MRTO4 6.575 6.703 7.788 10.312 10.971 9.944 10.330 0.0024891 mRNA turnover 4 homolog (S. cerevisiae) CCDC13 0.648 0.648 0.648 4.021 4.728 3.773 10.361 0.0006735 coiled-coil domain containing 13 NPB 0.648 1.649 0.729 4.021 4.602 4.748 10.361 0.0013459 neuropeptide B OXT 0.648 0.648 2.401 4.021 4.428 4.901 10.361 0.0054728 oxytocin, prepropeptide RASSF7 4.423 4.477 5.905 7.309 9.288 9.036 10.431 0.0049383 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 C19orf21 0.648 3.046 3.745 5.256 7.128 4.602 10.433 0.0182971 chromosome 19 open reading frame 21 HTR3B 6.930 2.780 5.082 8.242 8.474 8.812 10.499 0.0125993 5-hydroxytryptamine (serotonin) receptor 3B LEAP2 0.648 0.648 0.729 4.021 4.043 4.389 10.515 0.0002603 liver expressed antimicrobial peptide 2 ZSCAN5A 0.648 0.648 1.719 5.133 4.043 3.966 10.515 0.0028967 zinc finger and SCAN domain containing 5A PLK1S1 0.648 2.202 0.729 4.632 4.043 5.230 10.515 0.0036447 polo-like kinase 1 substrate 1 TMEM213 5.503 4.557 4.169 7.751 7.952 8.465 10.516 0.0023809 transmembrane protein 213 SLC4A3 6.145 3.708 3.518 6.912 8.407 7.603 10.518 0.0121168 solute carrier family 4, anion exchanger, member 3 OSTF1 8.090 6.007 6.047 10.163 9.403 10.397 10.528 0.0070111 osteoclast stimulating factor 1 GPR83 2.233 2.565 3.415 5.963 5.911 6.681 10.543 0.0016621 G protein-coupled receptor 83 CYP8B1 0.648 2.268 2.359 5.213 4.990 5.761 10.573 0.0029127 cytochrome P450, family 8, subfamily B, polypeptide 1 HHIPL1 4.620 2.648 3.320 7.471 6.731 6.728 10.639 0.0038049 HHIP-like 1 RPAP2 2.648 3.297 2.999 6.476 6.709 5.137 10.639 0.0043920 RNA polymerase II associated protein 2 ZSCAN16 1.648 1.648 1.648 5.973 5.060 4.236 10.641 0.0023359 zinc finger and SCAN domain containing 16 POLR3E 5.087 5.782 6.041 8.607 9.199 9.333 10.680 0.0012108 polymerase (RNA) III (DNA directed) polypeptide E (80kD) HIST1H1C 3.194 0.648 0.729 6.612 5.687 2.370 10.688 0.0242423 histone cluster 1, H1c NASP 7.297 7.602 8.422 10.949 11.022 11.573 10.700 0.0014811 nuclear autoantigenic sperm protein (histone-binding) RABL3 5.945 4.609 6.307 9.735 9.299 8.256 10.758 0.0042610 RAB, member of RAS oncogene family-like 3 FOXD2 0.648 1.245 2.401 5.355 3.633 5.830 10.768 0.0064302 forkhead box D2 MTHFR 7.715 6.393 7.287 10.446 9.912 11.146 10.788 0.0030749 methylenetetrahydrofolate reductase (NAD(P)H) MFSD7 5.042 3.620 6.047 8.551 8.478 8.166 10.819 0.0046222 major facilitator superfamily domain containing 7 SBF1 4.736 5.374 6.886 8.357 8.810 8.811 10.819 0.0079546 SET binding factor 1 MFSD9 1.648 1.648 1.834 5.485 5.088 2.752 10.852 0.0167768 major facilitator superfamily domain containing 9 ST7L 2.648 3.218 4.001 6.703 6.810 6.096 10.912 0.0027269 suppression of tumorigenicity 7 like ZBTB7B 6.756 5.499 6.140 9.588 9.818 9.170 10.913 0.0016530 zinc finger and BTB domain containing 7B KIAA0664 6.660 7.575 5.365 9.713 10.587 10.110 10.925 0.0036808 KIAA0664 KIAA1161 2.970 3.942 5.189 7.107 7.396 7.659 10.957 0.0048004 KIAA1161 KIF1A 1.648 4.218 4.139 5.102 8.171 6.091 10.960 0.0205834 kinesin family member 1A BTG3 5.936 3.695 4.226 8.147 7.680 7.642 10.960 0.0066159 BTG family, member 3 NFE2L1 9.660 7.368 9.100 13.114 11.536 11.109 10.961 0.0110707 nuclear factor (erythroid-derived 2)-like 1 SLC34A2 3.648 6.243 7.096 8.082 11.067 7.103 10.967 0.0328038 solute carrier family 34 (sodium phosphate), member 2 DEXI 9.144 7.416 8.839 12.357 12.303 11.959 11.030 0.0016801 Dexi homolog (mouse) SIN3A 8.510 7.806 7.949 11.414 11.014 12.108 11.041 0.0013730 SIN3 homolog A. transcription regulator (yeast) DDR2 6.950 4.869 5.169 9.869 8.929 8.338 11.073 0.0066250 discoidin domain receptor tyrosine kinase 2 TCHP 4.969 3.475 4.394 7.733 7.933 7.865 11.085 0.0013820 trichoplein, keratin filament binding ATP6V1B1 4.008 2.625 3.499 6.308 7.483 6.333 11.119 0.0036267 ATPase, H+ transporting, lysosomal 56/58 kDa, V1 subunit B1 KLHDC9 0.648 0.648 1.753 3.351 4.990 5.230 11.132 0.0043331 kelch domain containing 9 PRC1 3.860 0.648 2.268 5.894 4.870 5.761 11.259 0.0119109 protein regulator of cytokinesis 1 PRKDC 7.197 6.631 7.920 11.110 10.790 10.134 11.333 0.0021023 protein kinase, DNA-activated, catalytic polypeptide NOC4L 6.710 6.169 7.093 10.252 10.604 9.563 11.401 0.0013640 nucleolar complex associated 4 homolog (S. cerevisiae) ADCK5 5.042 1.648 3.904 7.793 6.969 7.423 11.461 0.0065078 aarF domain containing kinase 5 SGTA 8.472 4.673 9.701 11.573 12.001 12.771 11.545 0.0094437 small glutamine-rich tetratricopeptide repeat (TPR)- containing, alpha SCRIB 6.592 3.948 6.972 10.122 10.410 10.019 11.553 0.0031400 scribbled homolog (Drosophila) AATK 0.648 0.999 2.401 4.529 5.053 4.262 11.556 0.0043241 apoptosis-associated tyrosine kinase NCAPD3 2.648 4.557 2.970 6.501 6.889 6.181 11.557 0.0059484 non-SMC condensin II complex, subunit D3 ZNF384 7.837 6.428 6.852 10.386 10.468 10.327 11.578 0.0018991 zinc finger protein 384 FBXW5 9.034 7.279 8.785 12.573 11.795 11.034 11.621 0.0049293 F-box and WD repeat domain containing 5 CASP8 5.377 4.848 5.514 8.226 8.916 9.061 11.625 0.0008815 caspase 8, apoptosis-related cysteine peptidase ANAPC2 5.768 4.577 4.007 8.416 7.549 8.419 11.654 0.0039719 anaphase promoting complex subunit 2 FAM83E 5.452 3.814 5.304 8.512 8.621 9.009 11.770 0.0013279 family with sequence similarity 83. member E DOCK9 5.751 4.494 4.174 8.052 7.766 8.292 11.778 0.0034964 dedicator of cytokinesis 9 CCDC127 4.142 5.205 6.592 8.764 9.094 8.645 11.783 0.0045646 coiled-coil domain containing 127 REPIN1 8.839 6.352 6.959 10.657 10.701 9.922 11.877 0.0104246 replication initiator 1 BCL2L12 5.109 4.876 5.847 8.684 8.643 8.767 11.916 0.0008225 BCL2-like 12 (proline rich) RNASEH2C 2.233 2.233 2.991 6.770 5.811 4.777 11.939 0.0047012 ribonuclease H2, subunit C SPSB3 8.515 6.780 3.891 10.359 10.000 11.095 11.948 0.0105258 splA/ryanodine receptor domain and SOCS box containing 3 TSEN54 5.644 4.457 5.551 8.461 9.240 8.654 12.092 0.0014361 tRNA splicing endonuclease 54 homolog (S. cerevisiae) XRCC6 10.802 10.443 11.398 14.405 14.473 14.080 12.158 0.0008406 X-ray repair complementing defective repair in Chinese hamster cells 6 LRRC10 0.648 0.648 0.729 3.871 4.728 4.262 12.245 0.0004794 leucine rich repeat containing 10 SLC22A9 0.648 0.648 0.648 2.202 4.428 4.262 12.245 0.0094347 solute carrier family 22 (organic anion transporter), member 9 SNORD34 0.648 1.962 3.351 4.262 5.865 5.961 12.245 0.0099983 small nucleolar RNA, C/D box 34 ACRBP 0.648 0.648 0.648 4.529 0.648 4.262 12.245 0.0409719 acrosin binding protein ZNF767 4.525 2.814 4.876 8.122 8.400 8.140 12.251 0.0012288 zinc finger family member 767 TSPYL2 10.396 9.577 10.805 14.011 12.942 14.609 12.255 0.0028087 TSPY-like 2 CFP 4.734 3.420 3.296 7.303 6.914 7.554 12.274 0.0022215 complement factor properdin SNORA57 3.194 2.593 0.648 4.748 5.246 6.823 12.373 0.0096510 small nucleolar RNA. H/ACA box 57 SECISBP2 7.068 5.153 6.509 10.596 10.142 9.735 12.403 0.0017251 SECIS binding protein 2 SURF2 0.648 0.648 0.999 4.632 4.311 3.043 12.409 0.0033889 surfeit 2 LOC283663 2.970 3.067 5.412 7.358 6.604 8.163 12.410 0.0073425 No description FBXO10 5.936 3.298 4.102 7.748 7.617 8.136 12.524 0.0067754 F-box protein 10 SCNM1 1.648 3.904 3.170 7.553 6.812 6.659 12.543 0.0019082 sodium channel modifier 1 PHKG1 1.648 1.648 1.648 4.017 5.304 5.398 12.603 0.0026277 phosphorylase kinase, gamma 1 (muscle) SHARPIN 6.911 5.396 6.225 10.149 9.883 9.122 12.625 0.0021986 SHANK-associated RH domain interactor RAB34 9.747 8.006 8.931 13.319 12.592 12.196 12.650 0.0018721 RAB34, member RAS oncogene family C9orf45 0.648 0.648 0.729 3.871 4.311 5.961 12.664 0.0014901 No description PRDM11 0.648 0.648 0.729 3.081 4.311 4.901 12.664 0.0028877 PR domain containing 11 PVT1 7.214 6.483 6.496 9.054 12.090 10.160 12.671 0.0061452 Pvt1 oncogene (non-protein coding) HSD11B1 4.972 5.859 7.615 9.647 9.077 9.543 12.848 0.0078562 hydroxysteroid (11-beta) dehydrogenase 1 ACOX3 1.648 3.904 4.351 7.369 7.592 7.882 12.890 0.0021806 acyl-CoA oxidase 3, pristanoyl SNORD22 4.647 2.593 4.602 7.390 8.344 7.924 12.974 0.0025958 small nucleolar RNA, C/D box 22 FOXE3 0.648 0.648 0.729 4.372 4.428 0.648 12.986 0.0422596 forkhead box E3 C19orf76 5.552 4.667 5.989 7.636 9.252 9.704 12.993 0.0052059 chromosome 19 open reading frame 76 ZNF836 1.648 1.648 2.245 5.973 5.312 5.353 13.036 0.0005154 zinc finger protein 836 SGK269 7.191 6.789 8.039 9.615 11.249 11.744 13.041 0.0047553 No description FAM50B 5.109 2.233 2.951 6.726 6.386 6.657 13.047 0.0107234 family with sequence similarity 50, member B ZNF33A 3.233 3.714 4.101 7.016 7.837 6.942 13.074 0.0009549 zinc finger protein 33A NCRNA00105 3.947 3.151 4.132 4.754 7.659 7.841 13.078 0.0170277 No description DTPS 5.690 6.424 5.052 9.401 9.546 8.967 13.099 0.0012648 CTP synthase WDR81 6.259 5.889 6.723 11.107 8.374 9.976 13.154 0.0060773 WD repeat domain 81 EPR1 5.264 1.978 4.692 5.997 8.411 8.872 13.172 0.0130173 effector cell peptidase receptor 1 (non-protein coding) CECR6 0.648 0.648 0.729 4.372 4.311 5.014 13.212 0.0002153 cat eye syndrome chromosome region, candidate 6 IGSF21 0.648 0.648 1.719 4.372 2.987 6.556 13.212 0.0099893 immunoglobin superfamily, member 21 GCHFR 0.648 3.431 3.871 7.185 6.592 7.156 13.217 0.0038139 GTP cyclohydrolase I feedback regulator SNAI3 2.233 2.233 2.704 4.908 5.968 9.074 13.314 0.0070562 snail homolog 3 (Drosophila) LGSN 0.648 0.648 1.245 3.871 4.990 4.389 13.369 0.0009910 lengsin, lens protein with glutamine synthetase domain BTN2A2 5.109 2.461 3.278 7.264 6.205 7.421 13.401 0.0084724 butyrophilin, subfamily 2, member A2 SLC23A3 1.648 1.648 1.648 4.878 5.405 7.777 13.521 0.0024080 solute carrier family 23 (nucleobase transporters), member 3 MRPL34 7.254 5.355 6.978 11.013 10.598 9.969 13.544 0.0017820 mitochondrial ribosomal protein L34 RFPL3S 0.648 2.941 1.649 5.355 5.411 5.761 13.565 0.0027719 RFPL3 antisense RNA (non-protein coding) GPR37L1 4.142 3.510 4.713 7.317 7.914 8.253 13.665 0.0010409 G protein-coupled receptor 37 like 1 PJA1 7.413 3.861 4.442 8.466 8.121 8.214 13.669 0.0184170 praja ring finger 1 RINT1 4.314 3.256 4.602 8.375 7.921 7.305 13.673 0.0012198 RAD50 interactor 1 NRN1L 3.194 0.648 2.359 6.398 5.411 6.133 13.682 0.0034319 neuritin 1 -like SNORD36C 7.188 6.684 8.703 10.458 11.754 11.622 13.684 0.0034229 small nucleolar RNA, C/D box 36C LOC642313 3.194 0.648 1.962 5.606 5.742 6.202 13.733 0.0029938 No description PLAC8L1 0.648 0.648 0.999 4.262 4.428 5.014 13.734 0.0003234 PLAC8-like 1 SCT 0.648 0.648 1.477 3.081 4.428 5.606 13.734 0.0059303 secretin LOC493754 8.585 7.733 8.893 11.782 12.181 12.679 13.788 0.0008135 No description GRID1 7.053 4.490 4.848 9.588 8.312 8.646 13.914 0.0084191 glutamate receptor, ionotropic, delta 1 ZNF570 1.648 1.648 2.177 5.459 4.945 6.040 14.032 0.0007775 zinc finger protein 570 ANAPC1 6.227 4.615 5.654 9.432 9.476 9.518 14.135 0.0007685 anaphase promoting complex subunit 1 RAGE 4.008 4.376 5.037 7.974 8.283 8.202 14.183 0.0005875 renal tumor antigen NCF4 2.648 3.791 4.241 6.476 7.734 7.753 14.203 0.0023449 neutrophil cytosolic factor 4, 40 kDa RGS12 6.235 5.153 6.640 9.155 10.065 10.271 14.222 0.0015539 regulator of G-protein signaling 12 RECQL4 2.970 3.233 4.343 6.526 7.360 8.174 14.226 0.0020572 RecQ protein-like 4 BCAN 4.423 2.601 4.505 7.996 7.558 8.343 14.296 0.0014631 brevican TNFRSF4 6.669 4.372 6.316 9.924 9.190 10.510 14.329 0.0027359 tumor necrosis factor receptor superfamily, member 4 SLC45A4 4.008 4.402 4.465 7.852 8.328 8.084 14.363 0.0002062 solute carrier family 45, member 4 IDO1 0.648 1.649 1.387 4.372 5.246 6.798 14.506 0.0018229 Description PRICKLES 3.456 4.514 4.818 8.025 8.388 8.688 14.665 0.0005695 prickle homolog 3 (Drosophila) LOC284551 0.648 3.980 0.648 4.529 4.870 4.602 14.735 0.0214201 No description RMND5B 5.688 4.492 4.883 9.585 9.071 8.280 14.890 0.0009459 required for meiotic nuclear division 5 homolog B (S. cerevisiae) EXTL3 6.870 5.070 6.362 11.076 10.080 8.971 14.940 0.0033619 exostoses (multiple)-like 3 C8orf86 5.400 5.119 6.628 9.455 9.958 9.023 14.967 0.0015359 chromosome 8 open reading frame 86 COX18 4.482 3.486 3.710 7.614 7.460 7.791 14.975 0.0005425 COX18 cytochrome c oxidase assembly homolog (S. cerevisiae) INTS12 4.647 4.262 3.980 8.181 8.551 7.847 14.977 0.0003144 integrator complex subunit 12 MNAT1 5.726 3.013 4.481 8.953 8.422 7.204 15.356 0.0058263 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) UCN 0.648 3.046 0.999 5.894 5.411 4.602 15.490 0.0047373 urocortin G6PD 7.905 7.528 9.221 12.805 12.079 11.482 15.498 0.0018811 glucose-6-phosphate dehydrogenase CD3E 6.070 2.233 2.722 6.190 7.057 9.488 15.528 0.0155373 CD3e molecule, epsilon (CD3-TCR complex) KCNK3 2.233 3.170 2.722 8.049 6.639 6.196 15.594 0.0009231 potassium channel, subfamily K. member 3 SPEG 3.792 2.648 2.871 6.240 8.218 6.838 15.633 0.0019442 SPEG complex locus ZNF692 5.377 4.273 5.235 8.826 8.972 9.346 15.655 0.0004253 zinc finger protein 692 SNORA21 0.648 0.648 1.477 4.632 4.990 5.230 15.822 0.0003324 small nucleolar RNA, H/ACA box 21 NUDT12 0.648 0.648 1.564 4.632 5.600 4.389 15.822 0.0008724 nudix (nucleoside diphosphate linked moiety X)-type motif 12 HOXC11 0.648 0.648 0.648 4.632 2.987 5.830 15.822 0.0040579 homeobox C11 TBC1D26 0.648 0.648 1.477 3.871 5.462 5.407 15.833 0.0012919 TBC1 domain family, member 26 CXorf15 2.233 2.649 4.221 6.239 6.710 7.624 16.059 0.0031158 No description PGS1 6.444 3.983 5.523 10.109 9.529 8.922 16.069 0.0021473 phosphatidylglycerophosphate synthase 1 MAP1S 8.181 7.405 8.625 12.188 12.474 12.157 16.085 0.0003054 microtubule-associated protein 1S BCAM 8.349 4.465 4.814 8.481 11.401 9.096 16.175 0.0164385 basal cell adhesion molecule (Lutheran blood group) CCT2 9.878 9.840 10.102 13.824 14.221 13.898 16.227 0.0001203 chaperonin containing TCP1, subunit 2 (beta) C17orf67 3.860 0.648 3.336 7.295 7.199 7.882 16.248 0.0018901 chromosome 17 open reading frame 67 SLED1 0.648 1.649 3.810 5.035 5.687 7.491 16.427 0.0076711 No description ZNF18 0.648 1.962 2.552 6.963 4.728 5.158 16.906 0.0044329 zinc finger protein 18 LOC654433 2.648 2.970 3.251 7.066 8.175 4.579 17.099 0.0093023 No description ABCB4 0.648 1.962 3.208 4.748 6.510 6.133 17.150 0.0049924 ATP-binding cassette, sub-family B (MDR/TAP), member 4 DECR2 3.947 4.983 6.306 8.447 9.153 9.094 17.277 0.0030569 2,4-dienoyl CoA reductase 2, peroxisomal SMARCA4 6.554 7.264 8.534 11.374 11.986 11.026 17.278 0.0016080 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 MESTIT1 4.620 3.659 4.621 8.136 7.836 8.742 17.398 0.0006464 MEST intronic transcript 1 (non-protein coding) LAT 5.322 3.508 5.696 8.509 8.314 9.833 17.592 0.0031581 linker for activation of T cells C1orf51 4.423 5.256 6.187 8.726 9.400 9.418 17.680 0.0013369 chromosome 1 open reading frame 51 FBXL8 4.647 0.648 2.170 7.135 6.331 6.367 18.343 0.0071234 F-box and leucine-rich repeat protein 8 ZNF844 0.648 0.648 1.564 5.452 4.311 5.761 18.347 0.0007234 zinc finger protein 844 GPATCH2 2.648 3.621 3.896 6.852 7.826 7.868 18.428 0.0007144 G patch domain containing 2 RAB39 0.648 0.648 0.729 4.854 4.990 3.966 18.457 0.0004073 RAB39, member RAS oncogene family CACNB1 5.404 4.918 6.934 9.131 9.644 10.205 18.546 0.0021716 calcium channel, voltage-dependent, beta 1 subunit PUS7L 0.648 0.648 0.648 4.372 4.870 5.014 18.660 0.0001293 pseudouridylate synthase 7 homolog (S. cerevisiae)-like ACTR5 4.264 5.186 5.611 9.415 9.520 9.044 18.757 0.0003504 ARP5 actin-related protein 5 homolog (yeast) SMURF1 8.266 6.625 8.664 12.432 12.705 12.497 18.776 0.0005244 SMAD specific E3 ubiquitin protein ligase 1 NPW 0.648 1.962 3.336 5.688 7.185 6.202 18.895 0.0023629 neuropeptide W KRBA1 3.619 4.075 4.916 8.712 9.172 7.723 19.112 0.0007005 KRAB-A domain containing 1 MGC12982 1.648 1.648 2.206 6.517 4.017 6.487 19.846 0.0043151 No description TKTL1 0.648 1.962 3.959 6.279 5.246 6.944 19.929 0.0066069 transketolase-like 1 NSMCE1 4.647 0.648 3.351 7.681 7.681 6.367 20.124 0.0062582 non-SMC element 1 homolog (S. cerevisiae) LRRC37A3 4.972 0.648 2.329 6.552 6.666 7.441 20.201 0.0075990 leucine rich repeat containing 37, member A3 PECR 0.648 0.648 1.719 5.813 4.990 5.606 20.282 0.0002783 peroxisomal trans-2-enoyl-CoA reductase ITGB7 4.647 2.268 2.987 5.764 7.494 8.995 20.368 0.0067983 integrin, beta 7 PRO0628 3.194 0.648 1.973 6.329 6.142 6.872 20.466 0.0011477 No description TBX2 9.232 6.609 4.244 11.368 9.502 10.966 20.481 0.0153196 T-box 2 CACNA1G 7.881 5.986 7.549 10.415 10.363 13.188 20.775 0.0054007 calcium channel, voltage-dependent, T type, alpha 1 G subunit ZIK1 0.648 0.648 0.648 5.035 5.196 3.351 20.919 0.0015990 zinc finger protein interacting with K protein 1 homolog (mouse) MGC16384 0.648 2.552 0.729 5.035 5.246 5.462 20.919 0.0017341 No description PTPN23 7.691 6.872 8.243 12.222 12.142 11.267 21.037 0.0005515 protein tyrosine phosphatase, non-receptor type 23 QRSL1 5.431 4.501 5.485 9.400 9.941 9.513 21.950 0.0001653 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 SLC1A5 10.089 9.315 12.001 14.578 14.943 14.478 22.450 0.0022395 solute carrier family 1 (neutral amino acid transporter), member 5 AIPL1 3.194 0.648 1.245 5.870 5.742 5.544 22.569 0.0026818 aryl hydrocarbon receptor interacting protein-like 1 C12orf59 3.194 0.648 1.245 5.355 5.742 6.006 22.569 0.0029217 chromosome 12 open reading frame 59 ANKRD34C 0.648 0.648 1.973 5.213 6.052 5.158 22.772 0.0005334 ankyrin repeat domain 340 NOL6 4.580 3.779 5.382 8.297 9.972 9.096 22.912 0.0007594 nucleolar protein family 6 (RNA-associated) ZNF93 1.648 2.649 2.413 6.831 6.232 7.198 23.410 0.0002243 zinc finger protein 93 ACCN3 2.970 3.151 4.318 7.521 8.090 8.403 23.431 0.0003594 amiloride-sensitive cation channel 3 NME2P1 1.648 1.648 1.834 5.707 6.232 6.389 23.507 0.0001113 non-metastatic cells 2, protein (NM23B) expressed in, pseudogene 1 NOL7 1.648 1.648 1.648 6.634 6.204 3.294 23.519 0.0080295 nucleolar protein 7, 27 kDa UPK3B 3.422 2.064 5.078 8.024 7.731 8.324 24.283 0.0019352 uroplakin 3B SS18L2 7.081 6.841 7.491 11.675 11.640 12.144 25.152 0.0000932 synovial sarcoma translocation gene on chromosome 18-like 2 RGPD1 2.233 2.951 2.233 7.147 7.451 6.906 25.508 0.0001023 RANBP2-like and GRIP domain containing 1 ZNF619 0.648 0.648 0.729 5.355 3.871 5.462 26.117 0.0006555 zinc finger protein 619 METTL2B 0.648 0.648 1.719 5.452 6.052 5.407 27.064 0.0001834 methyltransferase like2B EVPL 0.648 1.477 2.552 5.407 7.822 5.889 27.064 0.0014000 envoplakin DCXR 6.617 6.701 8.147 11.804 12.259 11.408 27.672 0.0003893 dicarbonyl/L-xylulose reductase SPSB2 0.648 0.648 2.329 7.148 5.462 5.889 28.225 0.0006014 splA/ryanodine receptor domain and SOCS box containing 2 C15orf48 3.860 3.043 0.648 7.328 8.263 7.907 29.119 0.0009140 chromosome 15 open reading frame 48 FCER1G 0.648 0.648 0.648 6.312 3.633 5.606 31.080 0.0013189 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide FANCB 4.972 0.648 0.648 5.894 5.865 6.202 37.176 0.0135546 Fanconi anemia, complementation group B FSD1 0.648 0.648 0.648 5.870 0.648 6.006 37.314 0.0271508 fibronectin type III and SPRY domain containing 1 DRG1 1.648 2.926 5.319 8.440 8.179 7.484 38.122 0.0030298 developmentally regulated GTP binding protein 1 HPDL 0.648 0.648 2.781 6.976 7.761 6.173 46.038 0.0003685 4-hydroxyphenylpyruvate dioxygenase-like CD101 1.648 1.648 2.281 5.652 7.742 7.958 51.175 0.0004343 CD101 molecule SIRPB2 0.648 1.753 4.728 8.298 7.353 8.323 93.363 0.0015449 signal-regulatory protein beta 2 PLEKHM1P 0.648 1.753 4.795 8.434 8.564 8.519 108.842 0.0007865 pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene

TABLE 5 Differentially Expressed Genes in CD24+ Breast Epithelial Cells Nulliparous (NP) Samples Parous (P) Samples CD24+ N48 CD24+ N58 CD24+ N43 CD24+ N37 CD24+ N39 CD24+ N40 Pseudo fold change P value Gene description Higher Expression in Nulliparous CIB1 1.559 10.620 10.983 1.559 1.559 1.559 533.984 0.0337103 calcium and integrin binding 1 (calmyrin) TFF3 10.240 9.888 9.115 4.390 6.708 3.059 −45.167 0.0023684 trefoil factor 3 (intestinal) MTCYB 13.943 8.170 12.290 7.242 7.324 7.214 −33.079 0.0206094 No description C7orf50 4.851 7.090 6.583 1.559 1.559 1.559 −32.538 0.0005825 chromosome 7 open reading frame 50 CCDC74A 3.188 4.443 5.095 −0.026 −0.026 −0.026 −22.144 0.0004559 coiled-coil domain containing 74A TFF1 11.621 11.941 10.851 6.961 7.801 6.437 −21.327 0.0003108 trefoil factor 1 SERPINA11 5.342 3.772 6.304 0.974 1.692 0.974 −20.636 0.0020169 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 PVRL2 10.407 11.119 10.946 6.896 6.702 6.732 −18.559 0.0001028 poliovirus receptor-related 2 (herpesvirus entry mediator B) SUSD3 4.215 7.127 6.140 1.974 2.377 1.974 −17.947 0.0036823 sushi domain containing 3 EIF6 8.452 11.035 10.066 5.906 6.278 5.930 −17.574 0.0022003 eukaryotic translation initiation factor 6 C5orf38 4.605 3.974 4.944 0.845 −0.026 −0.026 −17.137 0.0002057 chromosome 5 open reading frame 38 AGR3 7.230 7.178 6.051 1.911 3.949 3.264 −15.080 0.0017874 anterior gradient homolog 3 (Xenopus laevis) ATHL1 10.501 10.990 9.529 6.235 7.175 6.449 −14.070 0.0006930 ATH1, acid trehalase-like 1 (yeast) MRPS11 3.188 5.147 4.857 −0.026 −0.026 1.348 −13.926 0.0018066 mitochondrial ribosomal protein S11 NDUFB4 7.373 8.506 6.918 3.176 4.239 3.825 −13.380 0.0007682 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15 kDa FAM86B2 −0.026 4.592 3.693 −0.026 −0.026 −0.026 −13.165 0.0481616 family with sequence similarity 86, member B2 AZGP1 10.381 12.099 9.970 6.678 7.118 6.482 −13.019 0.0010906 alpha-2-glycoprotein 1, zinc-binding LOC389033 3.649 3.288 5.348 −0.026 1.169 −0.026 −12.770 0.0023078 No description GPAA1 6.766 8.943 9.141 5.190 5.519 5.126 −12.319 0.0065104 glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast) COBRA1 6.106 8.803 8.403 4.892 5.309 4.150 −11.264 0.0107836 cofactor of BRCA1 PMPCA 5.824 8.007 8.599 3.327 3.350 5.124 −11.119 0.0085541 peptidase (mitochondrial processing) alpha MRPL24 7.035 6.893 6.291 3.334 3.583 3.220 −10.941 0.0001842 mitochondrial ribosomal protein L24 MRPS33 5.605 5.240 4.954 1.474 4.016 1.819 −10.711 0.0099494 mitochondrial ribosomal protein S33 BMS1P5 5.492 5.644 4.208 0.845 1.169 3.335 −10.285 0.0070691 BMS1 pseudogene 5 CRB3 5.584 7.524 7.855 4.165 3.845 4.378 −10.263 0.0067038 crumbs homolog 3 (Drosophila) MTCO1 13.611 14.451 10.812 10.258 10.293 8.868 −10.214 0.0196493 No description PHGR1 7.919 5.175 8.219 4.568 4.706 3.591 −10.205 0.0191842 proline/histidine/glycine-rich 1 SCAND1 7.584 8.333 8.948 5.240 4.989 4.801 −10.149 0.0006431 SCAN domain containing 1 C9orf116 3.966 3.288 0.505 −0.026 −0.026 −0.026 −9.939 0.0267529 chromosome 9 open reading frame 116 EREG 6.353 7.355 4.883 4.050 2.559 2.559 −9.885 0.0082563 epiregulin ZNF467 4.851 5.416 5.049 2.826 1.559 1.559 −9.790 0.0010476 zinc finger protein 467 CCDC101 5.693 6.929 7.245 2.404 4.712 3.469 −9.775 0.0069839 coiled-coil domain containing 101 TPX2 5.086 4.235 5.066 1.474 3.324 0.974 −9.585 0.0080698 TPX2, microtubule-associated, homolog (Xenopus laevis) LOC646999 3.649 4.391 4.944 −0.026 1.169 2.108 −9.331 0.0037813 No description VAV3 6.325 8.384 8.618 4.529 5.169 5.288 −9.284 0.0088933 vav 3 guanine nucleotide exchange factor C12orf70 3.188 3.616 4.158 −0.026 −0.026 1.348 −9.279 0.0015679 chromosome 12 open reading frame 70 ZNF669 4.851 6.383 5.942 3.169 2.648 2.173 −9.276 0.0019547 zinc finger protein 669 RNF126P1 8.036 7.646 8.207 4.857 4.906 4.857 −9.054 0.0001566 ring finger protein 126 pseudogene 1 RPL10A 14.812 14.687 15.340 11.174 11.936 12.167 −9.020 0.0005150 ribosomal protein L10a MRPL54 6.771 6.849 7.016 3.013 4.222 3.704 −8.842 0.0004666 mitochondrial ribosomal protein L54 SELENBP1 8.470 7.815 8.228 4.510 5.084 5.753 −8.838 0.0008987 selenium binding protein 1 RTN2 4.054 5.749 7.379 2.610 3.496 2.404 −8.808 0.0167337 reticulon 2 ENY2 4.277 4.107 2.247 0.974 0.974 0.974 −8.768 0.0077767 enhancer of yellow 2 homolog (Drosophila) TMSB10 11.288 11.904 11.307 8.079 8.790 8.318 −8.661 0.0003592 thymosin beta 10 HSP90AB1 12.327 13.551 12.840 8.810 9.765 10.447 −8.598 0.0020706 heat shock protein 90 kDa alpha (cytosolic), class B member 1 SYTL1 6.465 6.431 7.194 3.327 3.772 3.650 −8.595 0.0003216 synaptotagmin-like 1 CHCHD5 7.062 7.022 7.572 3.922 4.303 4.062 −8.571 0.0001734 coiled-coil-helix-coiled-coil-helix domain containing 5 HMGCL 4.054 4.457 4.083 0.974 1.692 0.974 −8.453 0.0003699 3-hydroxymethyl-3-methylglutaryl-CoA lyase CHMP2B 6.820 6.172 5.046 3.108 3.090 3.376 −8.368 0.0027260 chromatin modifying protein 2B RNF166 2.878 5.109 5.169 2.108 0.974 0.974 −8.346 0.0085019 ring finger protein 166 ELF1 8.078 8.712 6.879 4.230 4.559 5.652 −8.339 0.0041827 E74-like factor 1 (ets domain transcription factor) LILRB3 6.203 7.262 6.613 3.022 4.207 3.922 −8.308 0.0015296 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 IFRD2 6.087 8.625 8.764 4.412 5.653 5.586 −8.220 0.0205986 interferon-related developmental regulator 2 PODXL2 7.074 6.172 7.483 4.050 4.367 3.787 −8.133 0.0013454 podocalyxin-like 2 COX8A 9.600 10.223 9.140 6.122 6.753 6.745 −8.096 0.0006186 cytochrome c oxidase subunit VIIIA (ubiquitous) REEP5 7.493 9.006 8.503 5.700 5.475 5.508 −7.970 0.0018173 receptor accessory protein 5 C19orf48 8.777 8.635 9.144 5.436 6.581 5.796 −7.899 0.0008473 chromosome 19 open reading frame 48 LRRC41 6.651 10.165 8.862 5.425 5.894 6.471 −7.824 0.0268918 leucine rich repeat containing 41 PTPRS 6.297 6.643 6.542 3.578 3.772 2.899 −7.801 0.0003377 protein tyrosine phosphatase, receptor type, S ITIH4 4.899 5.167 5.041 2.246 1.974 1.974 −7.592 0.0001243 inter-alpha (globulin) inhibitor H4 (plasma Kallikrein- sensitive glycoprotein) C11orf10 9.678 9.947 9.006 6.203 6.586 7.055 −7.422 0.0008365 chromosome 11 open reading frame 10 MGMT 4.749 6.036 6.229 2.836 3.176 3.152 −7.381 0.0029048 O-6-methylguanine-DNA methyltransferase FUZ 4.851 5.667 5.277 2.404 2.648 2.173 −7.325 0.0004021 fuzzy homolog (Drosophila) ARTN 5.720 5.269 8.216 2.404 3.459 3.059 −7.287 0.0079916 artemin ZNF232 1.913 3.335 2.835 −0.026 −0.026 −0.026 −7.263 0.0016063 zinc finger protein 232 EXOC3 6.184 8.234 7.461 4.616 4.444 4.951 −7.186 0.0057836 exocyst complex component 3 CLCN7 7.526 9.222 9.226 6.079 6.384 5.873 −7.173 0.0056470 chloride channel 7 LILRA5 3.758 3.922 3.799 0.974 0.974 0.974 −7.082 0.0000921 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 DDX11 4.208 4.158 3.826 0.845 2.636 1.348 −7.015 0.0054045 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 AHSA2 5.823 4.721 4.383 1.911 1.559 3.440 −7.013 0.0088266 AHA1, activator of heat shock 90 kDa protein ATPase homolog 2 (yeast) HPX 8.833 8.860 9.009 6.642 6.058 4.859 −6.973 0.0018665 hemopexin PIN1 6.644 7.219 7.212 4.410 4.013 4.422 −6.952 0.0003807 peptidylproly cis/trans isomerase, NIMA-interacting 1 VCL 10.749 11.195 9.860 7.199 8.101 7.963 −6.897 0.0019655 vinculin CBX8 3.758 3.997 4.619 1.845 0.974 0.974 −6.885 0.0010261 chromobox homolog 8 GSDMD 5.797 7.667 7.756 4.246 4.990 4.166 −6.800 0.0086332 gasdermin D PGLS 8.167 8.754 9.689 6.138 5.990 5.663 −6.793 0.0015572 6-phosphogluconolactonase MST1P2 5.577 4.930 5.421 −0.026 3.345 2.671 −6.729 0.0112041 macrophage stimulating 1 (hepatocyte growth factor-like) pseudogene 2 EPN1 6.666 8.478 8.825 5.840 5.728 5.600 −6.728 0.0133837 epsin 1 YIF1A 6.177 7.873 8.934 4.563 5.784 5.127 −6.713 0.0186616 Yip1 interacting factor homolog A (S. cerevisiae) HYAL2 4.042 5.759 5.262 2.518 2.627 2.296 −6.703 0.0041612 hyaluronoglucosaminidase 2 FUS 8.547 9.376 8.624 5.823 6.132 6.353 −6.610 0.0006823 fused in sarcoma ASCC2 4.126 5.838 5.924 3.043 3.204 2.899 −6.587 0.0099125 activating signal cointegrator 1 complex subunit 2 C12orf11 6.355 6.345 6.033 3.324 4.989 3.469 −6.539 0.0069946 chromosome 12 open reading frame 11 PMAIP1 7.993 7.235 6.735 3.841 4.529 5.607 −6.523 0.0058220 phorbol-12-myristate-13-acetate-induced protein 1 JOSD2 5.514 6.803 7.547 4.222 4.098 4.098 −6.520 0.0067544 Josephin domain containing 2 VPS37D 4.662 4.394 4.791 3.022 1.692 1.819 −6.506 0.0031113 vacuolar protein sorting 37 homolog D (S. cerevisiae) RPS20 11.070 11.541 9.016 7.823 8.371 8.821 −6.493 0.0250414 ribosomal protein S20 C1orf122 6.023 7.422 5.693 3.324 4.831 1.819 −6.490 0.0139586 chromosome 1 open reading frame 122 FAM22A 2.671 4.239 4.443 −0.026 −0.026 2.108 −6.483 0.0093853 family with sequence similarity 22, member A RRP7A 3.966 4.118 2.671 −0.026 −0.026 3.152 −6.483 0.0370929 ribosomal RNA processing 7 homolog A (S. cerevisiae) PRINS 4.797 5.638 5.214 2.518 2.296 2.695 −6.482 0.0005257 psoriasis associated RNA induced by stress (non-protein coding) C19orf10 8.829 9.050 8.383 5.723 6.487 5.689 −6.470 0.0007252 chromosome 19 open reading frame 10 ACTG1 14.586 15.068 13.525 11.545 11.805 12.398 −6.361 0.0045533 actin, gamma 1 MARCKSL1 9.853 10.736 10.478 7.185 7.464 8.113 −6.353 0.0011397 MARCKS-like 1 SNORD36A 2.671 3.088 2.636 −0.026 −0.026 2.108 −6.327 0.0206930 small nucleolar RNA, C/D box 36A FAM3D 3.188 3.825 2.636 −0.026 −0.026 2.671 −6.327 0.0302279 family with sequence similarity 3, member D JUP 11.875 12.471 12.973 9.255 9.831 9.838 −6.231 0.0010046 junction plakoglobin SERPINA1 8.496 8.443 5.886 5.106 5.858 4.752 −6.226 0.0258212 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 TACO1 3.649 6.286 6.229 2.836 3.649 2.671 −6.219 0.0270595 translational activator of mitochondrially encoded cytochrome c oxidase I MGAT4B 7.461 9.527 8.667 6.029 6.032 6.621 −6.209 0.0102901 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N- acetylglucosaminyltransferase, isozyme B FAM160A2 4.708 7.223 7.273 3.821 4.390 4.643 −6.191 0.0341911 family with sequence similarity 160, member A2 ARHGEF10L 8.903 9.103 9.493 6.275 6.563 6.845 −6.181 0.0004988 Rho guanine nucleotide exchange factor (GEF) 10-like SCUBE2 7.232 6.205 5.575 3.802 2.840 4.608 −6.165 0.0091711 signal peptide, CUB domain, EGF-like 2 ACBD4 4.137 5.273 6.032 2.650 1.559 2.650 −6.160 0.0048665 acyl-CoA binding domain containing 4 LASP1 7.207 8.076 6.702 4.675 4.484 4.585 −6.158 0.0014329 LIM and SH3 protein 1 C17orf106 5.167 5.041 4.591 2.246 2.858 1.974 −6.132 0.0009885 chromosome 17 open reading frame 106 TWF2 5.309 7.290 6.939 4.675 4.222 3.704 −6.128 0.0124444 twinfilin, actin-binding protein, homolog 2 (Drosophila) DUSP10 6.104 4.771 4.013 2.404 2.075 2.173 −6.054 0.0047782 dual specificity phosphatase 10 CD14 6.721 8.780 9.208 6.118 5.454 6.616 −6.032 0.0271312 CD14 molecule RPL35 13.350 12.355 13.885 10.017 10.757 11.257 −6.032 0.0056017 ribosomal protein L35 CCS 4.042 5.633 6.023 3.404 2.627 3.043 −6.021 0.0132180 copper chaperone for superoxide dismutase MTA1 8.119 9.199 8.140 5.412 6.611 6.247 −6.017 0.0047444 metastasis associated 1 ALKBH7 8.798 8.202 9.437 5.616 5.823 6.875 −6.002 0.0032617 alkB, alkylation repair homolog 7 (E. coli) ARVCF 5.414 6.740 6.276 3.484 3.711 4.085 −5.918 0.0031665 armadillo repeat gene deleted in velocardiofacial syndrome CSTF1 4.899 5.648 5.214 2.649 4.222 1.974 −5.915 0.0139693 cleavage stimulation factor, 3′ pre-RNA, subunit 1, 50 kDa C16orf89 4.215 5.410 5.313 1.974 2.858 1.974 −5.864 0.0025265 chromosome 16 open reading frame 89 TCEAL4 5.376 5.661 5.125 2.826 1.559 4.144 −5.858 0.0122072 transcription elongation factor A (SII)-like 4 ZNF775 1.913 2.525 4.240 −0.026 −0.026 −0.026 −5.857 0.0052418 zinc finger protein 775 FAM150B 3.188 2.525 1.169 −0.026 −0.026 −0.026 −5.857 0.0089639 family with sequence similarity 150, member B MIER2 4.918 6.164 6.144 2.782 3.350 3.616 −5.845 0.0034797 mesoderm induction early response 1, family member 2 TOMM34 6.319 7.250 6.565 3.907 4.030 4.590 −5.796 0.0013922 translocase of outer mitochondrial membrane 34 LENG9 8.034 7.405 7.562 4.821 5.030 6.399 −5.784 0.0075280 leukocyte receptor cluster (LRC) member 9 SNORD10 5.197 2.671 3.616 1.734 −0.026 2.671 −5.761 0.0396040 small nucleolar RNA, C/D box 10 OTUD5 7.134 8.489 8.724 5.426 6.012 5.972 −5.727 0.0065679 OTU domain containing 5 LGMN 7.074 7.780 7.146 4.839 4.565 5.010 −5.692 0.0006715 legumain RAB11B 8.150 9.341 8.247 5.884 5.667 5.747 −5.658 0.0011121 RAB11B, member RAS oncogene family LRGUK 3.758 3.659 3.469 0.974 1.692 0.974 −5.635 0.0007897 leucine-rich repeats and guanylate kinase domain containing NCRNA00116 4.290 5.540 5.117 2.859 2.627 2.296 −5.619 0.0027114 non-protein coding RNA 116 ARHGEF7 7.164 7.990 7.784 4.542 5.447 5.502 −5.613 0.0021811 Rho guanine nucleotide exchange factor (GEF) 7 FTSJD2 6.501 7.938 8.083 4.960 5.608 5.101 −5.562 0.0075173 FtsJ methyltransferase domain containing 2 RHOT2 6.868 8.612 9.093 6.143 6.172 5.895 −5.539 0.0174167 ras homolog gene family, member T2 SSNA1 6.275 8.714 9.056 6.248 6.419 4.755 −5.524 0.0434121 Sjogren syndrome nuclear autoantigen 1 PREB 5.642 7.418 6.509 4.264 3.914 4.050 −5.497 0.0048473 prolactin regulatory element binding SLC35A4 5.746 8.437 7.267 5.304 4.812 4.640 −5.484 0.0221711 solute carrier family 35, member A4 MPST 7.471 7.732 9.114 5.915 5.992 5.017 −5.478 0.0071381 mercaptopyruvate sulfurtransferase ARAF 4.892 7.380 6.366 3.913 4.786 3.296 −5.477 0.0257690 v-raf murine sarcoma 3611 viral oncogene homolog RAB40B 5.954 5.102 5.625 2.933 3.746 2.650 −5.471 0.0025587 RAB40B, member RAS oncogene family TSPAN13 5.861 5.984 3.978 2.296 3.041 3.532 −5.470 0.0157053 tetraspanin 13 C2orf81 4.662 3.482 3.426 0.974 0.974 2.348 −5.469 0.0081873 chromosome 2 open reading frame 81 ZNF771 4.851 4.144 5.145 2.404 3.187 1.559 −5.452 0.0073346 zinc finger protein 771 CXCL5 4.717 6.147 4.851 2.404 4.144 1.559 −5.452 0.0184121 chemokine (C-X-C motif) ligand 5 GSTZ1 4.421 4.890 5.621 2.825 3.090 1.974 −5.451 0.0047091 glutathione transferase zeta 1 CYP2D7P1 2.671 3.288 3.288 0.845 −0.026 1.348 −5.436 0.0038051 cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 1 CD9 8.176 7.852 6.430 5.734 4.276 5.369 −5.433 0.0125357 CD9 molecule PLEC1 9.927 11.395 10.461 7.493 8.697 8.957 −5.404 0.0119279 No description PVRL4 9.260 9.804 8.735 6.762 6.923 6.830 −5.389 0.0012740 poliovirus receptor-related 4 EEF1A1 8.856 9.090 8.279 5.806 6.434 7.394 −5.362 0.0080315 eukaryotic translation elongation factor 1 alpha 1 PTHLH 7.873 10.074 9.819 7.397 8.084 4.778 −5.359 0.0460008 parathyroid hormone-like hormone CHRNE 5.072 5.116 4.065 2.518 2.627 2.695 −5.356 0.0030207 cholinergic receptor, nicotinic, epsilon PLA2G15 4.793 6.211 7.042 4.212 3.809 3.484 −5.286 0.0161765 phospholipase A2, group XV MAD1L1 5.035 6.723 6.967 4.331 4.548 4.031 −5.251 0.0194037 MAD1 mitotic arrest deficient-like 1 (yeast) DCTN3 6.544 7.483 7.496 4.154 5.034 5.306 −5.244 0.0043546 dynactin 3 (p22) ZNF385B 4.512 2.627 3.950 1.559 1.559 1.559 −5.243 0.0103622 zinc finger protein 385B RPL13AP5 8.522 7.449 8.041 5.043 5.651 6.655 −5.241 0.0091566 ribosomal protein L13a pseudogene 5 NUP188 6.263 8.311 7.613 5.236 5.035 5.365 −5.194 0.0117790 nucleoporin 188 kDa PHC2 7.388 10.092 8.561 5.653 6.188 6.303 −5.182 0.0126462 polyhomeotic homolog 2 (Drosophila) IL13RA1 6.340 8.884 8.245 5.871 5.915 5.339 −5.182 0.0253070 interleukin 13 receptor, alpha 1 PRR23A 10.022 8.374 7.524 4.906 6.001 7.729 −5.182 0.0384405 proline rich 23A PCBP4 6.469 5.643 7.309 4.666 3.772 4.099 −5.169 0.0075956 poly(rC) binding protein 4 CDK9 7.849 9.353 9.182 6.425 6.846 6.816 −5.154 0.0083791 cyclin-dependent kinase 9 HINT2 6.023 6.288 6.613 4.801 3.922 3.304 −5.154 0.0046316 histidine triad nucleotide binding protein 2 MGAT3 3.336 3.607 2.531 0.974 0.974 0.974 −5.140 0.0022755 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N- acetylglucosaminyltransferase SLC22A18 7.694 6.794 7.665 4.687 5.334 4.608 −5.133 0.0017053 solute carrier family 22, member 18 SH3D20 4.605 4.592 5.191 2.836 −0.026 2.671 −5.116 0.0127245 SH3 domain containing 20 HOMER2 6.553 8.698 8.042 4.580 5.688 5.858 −5.112 0.0145710 homer homolog 2 (Drosophila) KATNB1 6.516 7.186 7.722 5.362 5.113 4.166 −5.100 0.0062740 katanin p80 (WD repeat containing) subunit B 1 CCNG1 6.194 5.874 4.134 3.469 3.343 3.846 −5.090 0.0258826 cyclin G1 EEF1G 13.037 12.050 11.621 9.275 10.042 10.562 −5.085 0.0084375 eukaryotic translation elongation factor 1 gamma RPLP2 14.300 14.300 13.621 11.012 11.959 11.999 −5.067 0.0024098 ribosomal protein, large, P2 LRRC48 4.353 3.032 4.512 1.559 1.559 2.173 −5.058 0.0074574 leucine rich repeat containing 48 SLC35B2 6.034 7.189 6.280 3.697 4.667 4.178 −5.056 0.0041182 solute carrier family 35, member B2 TOP1MT 4.028 3.854 1.692 1.474 1.692 0.974 −5.049 0.0421915 topoisomerase (DNA) I, mitochondrial EIF3K 9.513 8.330 8.745 5.626 6.491 7.183 −5.031 0.0064229 eukaryotic translation initiation factor 3, subunit K LOC728640 5.043 5.095 3.176 0.845 2.636 3.335 −5.030 0.0405940 No description FAM195B 8.791 9.696 10.644 6.768 7.366 7.714 −5.027 0.0079048 family with sequence similarity 195, member B RPL11 13.351 12.404 13.081 10.071 10.756 11.317 −5.011 0.0049724 ribosomal protein L11 EIF3G 8.241 9.149 8.893 5.918 6.620 6.756 −5.006 0.0025073 eukaryotic translation initiation factor 3, subunit G DYNLRB1 5.410 8.161 6.980 4.527 4.661 4.973 −4.989 0.0263070 dynein, light chain, roadblock-type 1 CNTROB 5.684 5.982 7.015 3.649 4.266 3.672 −4.956 0.0037490 centrobin, centrosomal BRCA2 interacting protein RPL37 12.750 10.540 10.627 8.232 9.584 9.813 −4.952 0.0346639 ribosomal protein L37 GADD45B 12.254 11.029 11.602 8.580 9.298 10.528 −4.941 0.0155971 growth arrest and DNA-damage-inducible, beta DPM2 7.159 8.235 7.804 5.927 5.518 4.856 −4.935 0.0040537 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit EFCAB4A 8.593 6.481 7.549 4.178 5.083 6.755 −4.935 0.0381489 EF-hand calcium binding domain 4A HOXB2 4.605 3.649 2.108 1.734 −0.026 1.348 −4.930 0.0221604 homeobox B2 NCRNA00173 3.953 3.251 4.120 0.974 0.974 1.819 −4.930 0.0018557 non-protein coding RNA 173 SEP4 5.410 3.583 6.255 1.974 2.858 3.954 −4.928 0.0414444 septin 4 PLSCR3 6.485 8.356 7.465 5.164 4.885 5.325 −4.927 0.0076754 phospholipid scramblase 3 KIAA1324 10.341 10.418 9.581 7.903 8.119 8.041 −4.922 0.0018388 KIAA1324 ANXA3 6.734 7.606 7.271 5.873 4.977 4.092 −4.905 0.0095088 annexin A3 CAPNS1 10.575 10.688 10.429 8.082 9.215 8.287 −4.886 0.0039125 calpain, small subunit 1 KIF7 3.188 2.525 2.263 −0.026 −0.026 1.348 −4.884 0.0081021 kinesin family member 7 RPS9 12.364 13.216 13.781 10.635 10.908 11.494 −4.879 0.0077590 ribosomal protein S9 ARRDC1 7.744 9.437 9.128 6.841 7.156 6.618 −4.860 0.0148350 arrestin domain containing 1 C1orf159 6.887 7.706 7.760 5.212 5.544 4.608 −4.856 0.0028834 chromosome 1 open reading frame 159 RAB32 6.404 6.424 6.587 3.922 4.312 4.235 −4.842 0.0002870 RAB32, member RAS oncogene family UROD 5.475 5.993 6.206 3.205 4.201 3.496 −4.823 0.0027575 uroporphyrinogen decarboxylase CTDSP1 6.973 9.606 8.201 6.553 5.933 5.796 −4.814 0.0238350 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 SDHAF2 6.168 8.056 7.920 5.145 5.793 4.946 −4.799 0.0169194 succinate dehydrogenase complex assembly factor 2 CENPH 6.023 6.034 4.391 3.772 2.402 2.878 −4.796 0.0099701 centromere protein H FAM82A2 5.045 6.853 6.222 3.854 4.327 3.963 −4.789 0.0128941 family with sequence similarity 82, member A2 NAT14 4.715 5.383 6.299 3.746 3.781 2.457 −4.783 0.0141312 N-acetyltransferase 14 (GCN5-related, putative) NPHP4 5.664 5.510 5.954 2.246 3.712 3.704 −4.731 0.0042041 nephronophthisis 4 YBX1 6.059 7.708 6.264 2.194 5.466 4.679 −4.728 0.0331788 Y box binding protein 1 EXOSC5 5.086 5.607 5.874 3.324 2.848 3.758 −4.717 0.0026792 exosome component 5 H1FX 10.383 8.882 8.843 7.653 7.048 6.608 −4.711 0.0095403 H1 histone family, member X MTX1 7.647 8.717 7.995 5.977 6.286 5.412 −4.707 0.0036309 metaxin 1 LMF2 7.028 8.812 8.731 6.202 6.263 6.578 −4.705 0.0203124 lipase maturation factor 2 SYCE1 5.273 4.309 3.831 1.559 2.075 3.440 −4.703 0.0191949 synaptonemal complex central element protein 1 KCNH6 6.677 7.036 5.536 4.448 2.169 5.482 −4.689 0.0386416 potassium voltage-gated channel, subfamily H (eag- related), member 6 NDUFAB1 3.059 5.945 4.875 2.610 3.032 2.650 −4.676 0.0477782 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8 kDa TSPAN1 5.440 6.253 5.455 4.032 3.343 2.296 −4.662 0.0057943 tetraspanin 1 TSSC4 6.469 6.850 7.216 4.255 4.367 5.083 −4.641 0.0021028 tumor suppressing subtransferable candidate 4 KRT86 3.687 3.525 3.727 1.474 0.974 1.819 −4.636 0.0011827 keratin 86 SPTBN1 8.181 9.945 8.352 6.143 6.083 6.726 −4.622 0.0065380 spectrin, beta, non-erythrocytic 1 LOC728448 3.059 3.767 3.897 1.559 1.559 1.559 −4.620 0.0019762 No description DEGS2 5.483 4.856 5.012 3.187 3.187 2.650 −4.615 0.0015956 degenerative spermatocyte homolog 2, lipid desaturase (Drosophila) UGDH 7.908 7.440 6.434 5.236 5.682 4.996 −4.608 0.0098734 UDP-glucose 6-dehydrogenase FBXO21 5.801 8.108 6.644 4.441 4.673 4.213 −4.607 0.0112256 F-box protein 21 LPCAT3 6.400 8.354 8.441 6.239 5.934 5.747 −4.603 0.0336662 lysophosphatidylcholine acyltransferase 3 TCTN2 5.789 5.037 6.249 3.205 2.840 4.255 −4.584 0.0083262 tectonic family member 2 POMP 10.079 10.860 10.091 7.959 8.396 7.886 −4.574 0.0016278 proteasome maturation protein PLXND1 5.678 7.229 7.184 5.038 4.719 4.148 −4.568 0.0126355 plexin D1 PKIG 6.658 7.293 6.205 5.076 5.102 3.565 −4.567 0.0123377 protein kinase (cAMP-dependent, catalytic) inhibitor gamma CFDP1 5.103 4.883 5.195 2.610 2.913 4.315 −4.563 0.0177866 craniofacial development protein 1 NDUFS3 7.350 7.514 6.842 4.693 4.989 5.325 −4.559 0.0013645 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30 kDa (NADH-coenzyme Q reductase) TRIM52 8.375 9.719 8.362 6.175 6.342 6.642 −4.553 0.0036930 tripartite motif-containing 52 VKORC1 4.952 4.574 3.743 1.559 3.032 1.559 −4.542 0.0087130 vitamin K epoxide reductase complex, subunit 1 ZFP57 4.353 5.233 6.485 4.013 3.600 2.173 −4.533 0.0304091 zinc finger protein 57 homolog (mouse) KRT18 5.369 5.253 5.783 3.088 4.301 3.077 −4.518 0.0077237 keratin 18 EMID1 6.066 5.064 5.510 3.334 3.954 2.860 −4.516 0.0047989 EMI domain containing 1 ASH2L 4.290 6.379 5.209 3.343 3.041 2.296 −4.491 0.0111481 ash2 (absent, small, or homeotic)-like (Drosophila) CDK10 3.364 5.410 6.100 2.859 3.248 3.293 −4.476 0.0481389 cyclin-dependent kinase 10 SNRNP70 8.893 10.882 10.733 7.587 7.761 8.721 −4.470 0.0199655 small nuclear ribonucleoprotein 70 kDa (U1) B4GALNT4 9.035 9.248 10.024 6.964 7.088 7.357 −4.469 0.0017552 beta-1,4-N-acetyl-galactosaminyl transferase 4 C1orf77 6.066 6.066 4.134 2.860 1.974 4.098 −4.467 0.0211335 chromosome 1 open reading frame 77 C17orf101 3.593 5.376 5.201 2.246 2.377 3.220 −4.457 0.0153876 chromosome 17 open reading frame 101 AKIRIN1 8.664 8.221 7.784 5.632 5.632 6.996 −4.444 0.0087843 akirin 1 PPP1CA 5.799 6.549 6.074 4.422 3.648 3.907 −4.440 0.0023292 protein phosphatase 1, catalytic subunit, alpha isozyme NDUFA11 8.300 9.744 8.755 6.986 7.194 6.154 −4.426 0.0089355 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7 kDa STARD10 4.851 4.316 4.976 2.610 3.032 2.173 −4.417 0.0026370 StAR-related lipid transfer (START) domain containing 10 SPAG7 7.455 6.990 8.184 5.277 6.342 4.851 −4.407 0.0122970 sperm associated antigen 7 ZAP70 1.913 2.108 2.108 −0.026 −0.026 −0.026 −4.387 0.0002272 zeta-chain (TCR) associated protein kinase 70 kDa GLTPD2 1.913 2.108 3.335 −0.026 −0.026 −0.026 −4.387 0.0030100 glycolipid transfer protein domain containing 2 GOLGA6L1 2.671 1.098 2.108 −0.026 −0.026 −0.026 −4.387 0.0086539 golgin A6 family-like 1 CPLX1 7.311 6.162 7.548 5.178 5.590 3.704 −4.385 0.0177199 complexin 1 CES8 5.248 4.107 4.761 1.974 1.974 3.660 −4.384 0.0144060 No description MAFK 11.235 10.641 12.120 8.514 9.271 9.728 −4.368 0.0097467 v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) STAP2 6.168 5.450 6.624 2.518 4.504 4.042 −4.364 0.0117022 signal transducing adaptor family member 2 INPP5J 4.153 5.199 5.806 3.205 2.782 3.077 −4.354 0.0094152 inositol polyphosphate-5-phosphatase J CBLC 6.082 6.120 5.634 3.351 3.960 4.327 −4.352 0.0029992 Cas-Br-M (murine) ecotropic retroviral transforming sequence c COL9A2 5.352 6.025 6.615 3.907 3.604 4.286 −4.341 0.0053592 collagen, type IX, alpha 2 PLCB4 5.642 4.674 4.255 3.043 2.559 2.559 −4.332 0.0054413 phospholipase C, beta 4 WBSCR26 4.054 3.469 5.135 3.022 2.848 0.974 −4.328 0.0377759 Williams Beuren syndrome chromosome region 26 (non- protein coding) SRP14 6.588 6.206 5.980 4.098 4.521 3.565 −4.311 0.0022970 signal recognition particle 14 kDa (homologous Alu RNA binding protein) CUTA 9.657 8.275 8.536 6.167 6.843 7.231 −4.311 0.0099233 cutA divalent cation tolerance homolog (E. coli) R3HCC1 6.722 7.651 8.414 5.324 6.308 5.302 −4.307 0.0163791 R3H domain and coiled-coil containing 1 GTPBP2 8.282 8.576 7.382 6.049 5.909 6.473 −4.295 0.0064589 GTP binding protein 2 TNFRSF14 7.079 7.031 7.427 4.752 4.977 5.428 −4.291 0.0012318 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) GSTA1 3.188 5.023 4.208 −0.026 3.345 2.108 −4.286 0.0457790 glutathione S-transferase alpha 1 RALGDS 11.057 11.076 10.669 8.575 8.950 9.573 −4.272 0.0041934 ral guanine nucleotide dissociation stimulator ZNF44 5.273 5.554 4.705 2.610 4.144 3.059 −4.271 0.0131896 zinc finger protein 44 RPL27A 10.238 7.636 8.238 6.012 6.151 7.550 −4.247 0.0377652 ribosomal protein L27a BAI2 5.344 5.125 4.296 2.859 3.041 3.043 −4.239 0.0038642 brain-specific angiogenesis inhibitor 2 TRAP1 8.713 8.729 8.617 6.052 6.915 6.631 −4.236 0.0014137 TNF receptor-associated protein 1 RAE1 4.899 4.526 3.838 1.974 2.377 2.819 −4.229 0.0050791 RAE1 RNA export 1 homolog (S. pombe) HES4 10.391 10.675 11.686 8.322 8.600 8.601 −4.215 0.0026017 hairy and enhancer of split 4 (Drosophila) SDHAFI 3.954 5.325 5.270 2.860 3.196 3.220 −4.210 0.0136209 succinate dehydrogenase complex assembly factor 1 PPME1 6.106 7.180 6.612 4.283 4.543 5.098 −4.196 0.0054712 protein phosphatase methylesterase 1 CSRP1 13.321 12.373 13.440 10.100 11.253 11.548 −4.193 0.0112794 cysteine and glycine-rich protein 1 XRN2 7.448 7.883 6.166 5.381 5.794 5.349 −4.191 0.0230084 5′-3′ exoribonuclease 2 ABHD14B 7.805 7.225 8.018 4.670 5.740 6.005 −4.183 0.0056631 abhydrolase domain containing 14B PXMP2 1.913 2.671 2.038 −0.026 −0.026 −0.026 −4.181 0.0009777 peroxisomal membrane protein 2, 22 kDa EGR4 2.671 1.169 2.038 −0.026 −0.026 −0.026 −4.181 0.0075472 early growth response 4 TMSB15A 3.966 2.038 1.734 −0.026 −0.026 −0.026 −4.181 0.0088649 thymosin beta 15a MUSTN1 2.671 2.525 2.038 −0.026 −0.026 1.348 −4.181 0.0103116 musculoskeletal, embryonic nuclear protein 1 POM121L1P 4.749 1.098 2.038 −0.026 −0.026 −0.026 −4.181 0.0278657 POM121 membrane glycoprotein-like 1, pseudogene BTBD19 2.671 2.836 2.038 −0.026 −0.026 2.108 −4.181 0.0373246 BTB (POZ) domain containing 19 ZDHHC4 7.345 6.359 6.090 4.296 5.545 3.809 −4.177 0.0169409 zinc finger, DHHC-type containing 4 RANGRF 4.137 3.885 3.032 1.559 2.075 1.559 −4.175 0.0052909 RAN guanine nucleotide release factor DDX41 7.504 8.158 7.446 5.385 5.591 5.494 −4.174 0.0010154 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 ARMC6 5.537 7.120 7.690 4.840 5.061 5.576 −4.169 0.0435180 armadillo repeat containing 6 CHI3L2 9.895 11.472 10.081 8.785 8.393 7.843 −4.146 0.0106815 chitinase 3-like 2 RPL10 15.252 14.909 14.712 12.304 13.087 13.201 −4.145 0.0028197 ribosomal protein L10 COQ10A 4.137 3.663 3.604 1.559 2.454 1.559 −4.125 0.0043761 coenzyme Q10 homolog A (S. cerevisiae) SYNGR2 9.935 11.373 9.596 7.891 8.064 7.655 −4.125 0.0060038 synaptogyrin 2 LRRC16B 2.519 4.997 3.600 2.650 1.559 1.559 −4.114 0.0477276 leucine rich repeat containing 16B HSD17B8 4.572 4.413 4.170 1.974 2.377 3.220 −4.100 0.0071773 hydroxysteroid (17-beta) dehydrogenases GHDC 3.810 5.509 5.106 2.559 3.476 2.899 −4.091 0.0195848 GH3 domain containing CD2AP 6.208 5.839 4.808 4.177 3.742 3.789 −4.087 0.0132863 CD2-associated protein RPL13 14.215 13.942 14.098 11.644 12.067 12.646 −4.086 0.0031220 ribosomal protein L13 ATP5F1 7.677 7.613 5.718 5.583 4.732 5.643 −4.084 0.0422878 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 ZC3H11A 5.954 7.876 6.820 5.036 4.459 4.792 −4.078 0.0116807 zinc finger CCCH-type containing 11A MLPH 6.304 5.748 4.930 4.277 3.519 3.557 −4.075 0.0110046 melanophilin BRD9 6.599 7.619 7.882 4.608 5.768 5.593 −4.073 0.0107943 bromodomain containing 9 COPB2 6.509 6.722 5.308 4.703 4.116 3.557 −4.054 0.0115318 coatomer protein complex, subunit beta 2 (beta prime) RPN1 8.646 8.874 7.909 6.289 6.627 6.820 −4.053 0.0044267 ribophorin I ZNF512B 6.617 7.937 8.263 5.785 6.248 5.657 −4.040 0.0207038 zinc finger protein 512B IMPDH2 8.405 8.352 7.345 5.350 6.317 6.392 −4.038 0.0090115 IMP (inosine 5′-monophosphate) dehydrogenase 2 MRPS12 4.946 7.849 6.366 4.355 4.866 4.042 −4.032 0.0423469 mitochondrial ribosomal protein S12 TACSTD2 12.015 11.922 11.277 9.911 9.917 9.897 −4.030 0.0024589 tumor-associated calcium signal transducer 2 ARFRP1 4.554 7.410 5.977 3.973 3.747 4.561 −4.012 0.0466815 ADP-ribosylation factor related protein 1 KRT10 3.966 6.003 4.675 2.108 2.836 2.671 −4.011 0.0102302 keratin 10 TARSL2 2.747 4.514 3.976 1.974 1.974 1.974 −4.003 0.0173868 threonyl-tRNA synthetase-like 2 ESRRA 7.538 9.461 9.511 7.336 7.510 7.081 −4.002 0.0497314 estrogen-related receptor alpha SIN3B 8.127 9.670 8.823 6.823 7.224 6.681 −4.001 0.0095510 SINS homolog B, transcription regulator (yeast) CLPP 5.009 6.510 7.035 4.514 4.351 4.684 −3.990 0.0314106 CIpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli) NME7 6.904 6.587 5.191 4.118 4.906 4.592 −3.985 0.0254605 non-metastatic cells 7, protein expressed in (nucleoside- diphosphate kinase) GTF2H4 5.584 6.606 7.802 4.401 5.410 4.614 −3.980 0.0309248 general transcription factor IIH, polypeptide 4, 52 kDa C14orf142 4.137 3.552 3.059 1.559 2.075 1.559 −3.980 0.0058864 chromosome 14 open reading frame 142 DUSP16 4.899 3.966 2.973 2.860 1.974 1.974 −3.976 0.0328235 dual specificity phosphatase 16 MAP3K11 6.664 8.405 8.386 6.418 5.857 5.439 −3.964 0.0215372 mitogen-activated protein kinase kinase kinase 11 SFT2D1 5.453 5.381 4.901 3.396 4.479 2.602 −3.960 0.0220253 SFT2 domain containing 1 G6PC 4.353 5.378 5.998 3.872 4.013 1.559 −3.960 0.0401942 glucose-6-phosphatase, catalytic subunit DULLARD 5.500 6.633 5.444 3.462 4.049 4.085 −3.952 0.0074344 No description ACAD8 5.344 5.756 4.076 3.043 3.697 3.364 −3.944 0.0219478 acyl-CoA dehydrogenase family, member 8 BATF 9.004 9.251 9.677 7.020 7.845 7.272 −3.943 0.0036117 basic leucine zipper transcription factor, ATF-like COX5B 5.690 6.396 5.382 4.035 4.421 3.293 −3.931 0.0092241 cytochrome c oxidase subunit Vb PTP4A2 8.227 9.403 7.125 6.252 6.100 6.869 −3.929 0.0302172 protein tyrosine phosphatase type IVA, member 2 DUSP4 7.614 7.248 6.394 5.217 5.275 5.413 −3.926 0.0076915 dual specificity phosphatase 4 ZNF777 4.421 6.068 6.099 3.196 4.098 4.098 −3.917 0.0292724 zinc finger protein 777 SEMA4B 10.093 10.853 11.090 8.887 8.914 8.210 −3.907 0.0048204 sema domain, immunoglobulin domain (ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B NPDC1 10.084 9.870 9.747 7.204 7.905 8.209 −3.907 0.0023891 neural proliferation, differentiation and control, 1 SEP2 7.885 8.586 7.119 5.452 5.922 6.196 −3.899 0.0089248 septin 2 LUC7L2 5.456 7.309 7.087 4.686 5.348 5.016 −3.892 0.0363622 LUC7-like 2 (S. cerevisiae) AP1AR 4.870 5.350 4.534 2.911 3.277 2.899 −3.888 0.0028941 adaptor-related protein complex 1 associated regulatory protein METRN 6.589 7.969 7.650 6.012 5.548 5.152 −3.883 0.0130522 meteorin, glial cell differentiation regulator BRMS1 4.353 4.765 3.388 2.404 1.559 2.650 −3.863 0.0121750 breast cancer metastasis suppressor 1 MAPT 7.919 6.694 6.616 5.325 5.094 4.670 −3.852 0.0078780 microtubule-associated protein tau ANO9 5.159 7.026 6.867 4.428 4.419 5.082 −3.847 0.0314635 anoctamin 9 ATG16L2 5.127 5.839 7.070 4.144 3.187 4.705 −3.838 0.0244513 ATG16 autophagy related 16-like 2 (S. cerevisiae) ZNF598 9.693 11.012 10.132 8.192 8.034 8.414 −3.837 0.0049939 zinc finger protein 598 DYNC2LI1 3.758 3.772 3.089 2.848 0.974 1.819 −3.836 0.0286370 dynein, cytoplasmic 2, light intermediate chain 1 C6orf59 1.913 1.913 1.098 −0.026 −0.026 −0.026 −3.832 0.0049831 No description C6orf57 1.913 1.098 2.038 −0.026 −0.026 −0.026 −3.832 0.0053377 chromosome 6 open reading frame 57 SALL2 1.913 2.835 2.835 0.845 1.169 −0.026 −3.832 0.0113116 sal-like 2 (Drosophila) MCM9 1.913 2.108 2.038 −0.026 −0.026 1.348 −3.832 0.0193292 minichromosome maintenance complex component 9 POP5 4.282 3.412 2.734 1.474 1.692 0.974 −3.830 0.0084766 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) TRPC4AP 9.521 10.055 10.220 7.656 8.284 8.026 −3.828 0.0027682 transient receptor potential cation channel, subfamily C, member 4 associated protein SH3GL1 9.092 9.023 9.004 6.681 7.377 7.087 −3.825 0.0012425 SH3-domain GRB2-like 1 SERPINA3 11.483 12.786 10.557 8.724 9.551 9.700 −3.817 0.0150507 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), members EIF3D 9.096 10.765 9.920 7.966 7.989 8.621 −3.811 0.0191374 eukaryotic translation initiation factor 3, subunit D ADRM1 8.325 9.953 9.590 7.661 7.950 7.525 −3.807 0.0244728 adhesion regulating molecule 1 DAP 6.441 5.916 5.219 3.988 4.296 3.717 −3.804 0.0076362 death-associated protein ACAD11 7.275 6.185 7.174 5.348 5.076 4.899 −3.802 0.0082671 acyl-CoA dehydrogenase family, member 11 ZFYVE28 3.810 4.484 4.750 2.559 2.559 2.559 −3.797 0.0039286 zinc finger, FYVE domain containing 28 C17orf70 6.245 6.878 7.380 4.741 4.337 5.456 −3.796 0.0086869 chromosome 17 open reading frame 70 TMEM199 3.475 4.187 3.447 1.559 1.559 1.559 −3.772 0.0012533 transmembrane protein 199 SETD3 4.961 5.815 4.469 2.559 2.840 4.081 −3.757 0.0188726 SET domain containing 3 PPP1R1B 7.074 5.710 6.626 3.802 4.367 5.645 −3.753 0.0267260 protein phosphatase 1, regulatory (inhibitor) subunit 1B RPS15A 11.974 10.121 10.779 8.214 9.518 9.513 −3.752 0.0280599 ribosomal protein S15a C19orf40 7.597 7.896 6.319 4.856 4.997 5.990 −3.748 0.0158580 chromosome 19 open reading frame 40 NUDT16L1 2.878 2.878 3.063 0.974 0.974 0.974 −3.741 0.0002594 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 NR2E3 2.878 3.469 3.246 0.974 0.974 1.819 −3.741 0.0040645 nuclear receptor subfamily 2, group E, member 3 NTAN1 2.878 4.282 2.531 0.974 0.974 1.819 −3.741 0.0165886 N-terminal asparagine amidase SMTN 10.362 9.095 10.915 7.600 8.179 9.012 −3.740 0.0270744 smoothelin P2RX4 7.702 7.563 8.912 5.662 6.654 6.851 −3.734 0.0255180 purinergic receptor P2X, ligand-gated ion channel, 4 U2AF1L4 6.044 5.529 5.589 3.950 4.144 3.440 −3.733 0.0029156 U2 small nuclear RNA auxiliary factor 1-like 4 TMEM88 6.757 5.918 6.697 3.022 4.989 4.801 −3.723 0.0156178 transmembrane protein 88 DNAJC17 4.968 6.596 7.659 3.772 4.794 4.701 −3.719 0.0382279 DnaJ (Hsp40) homolog, subfamily C. member 17 PLEKHG3 7.752 7.454 7.556 5.560 6.159 5.657 −3.716 0.0020599 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 PPP1CC 6.329 8.017 6.906 4.442 5.158 5.345 −3.699 0.0113484 protein phosphatase 1, catalytic subunit, gamma isozyme NUP88 7.306 7.323 5.874 5.113 5.435 5.238 −3.699 0.0226163 nucleoporin 88 kDa RPL7 11.516 10.027 9.517 7.631 8.552 8.927 −3.697 0.0245625 ribosomal protein L7 C1orf35 7.455 7.020 7.962 5.689 5.457 5.571 −3.691 0.0030583 chromosome 1 open reading frame 35 C19orf20 4.685 5.429 5.499 3.032 3.617 3.307 −3.687 0.0039394 chromosome 19 open reading frame 20 SLC37A4 3.364 4.638 4.178 2.518 2.296 2.296 −3.686 0.0101044 solute carrier family 37 (glucose-6-phosphate transporter), member 4 ZNF689 3.336 4.282 3.089 1.474 2.402 0.974 −3.681 0.0141504 zinc finger protein 689 H2AFX 6.721 7.237 6.647 3.872 5.033 5.360 −3.674 0.0079478 H2A histone family, member X DAZAPI 9.008 10.448 9.977 8.100 8.426 8.057 −3.673 0.0161942 DAZ associated protein 1 C19orf63 8.378 10.164 10.087 8.289 8.069 7.992 −3.667 0.0479325 chromosome 19 open reading frame 63 TTRAP 3.758 3.922 2.848 2.404 0.974 1.819 −3.664 0.0178603 No description ANKRD52 7.123 8.513 8.154 6.601 6.183 6.283 −3.659 0.0175449 ankyrin repeat domain 52 SEMA3B 11.533 11.512 12.860 9.643 10.872 10.044 −3.652 0.0210944 sema domain, immunoglobulin domain (ig), short basic domain, secreted, (semaphorin) 3B MKRN2 4.205 5.867 4.943 2.782 3.026 3.999 −3.651 0.0263830 makorin ring finger protein 2 SAE1 7.031 7.920 7.531 6.053 5.591 5.325 −3.649 0.0051696 SUMO1 activating enzyme subunit 1 REEP6 6.863 7.174 6.920 5.293 5.309 4.222 −3.642 0.0042924 receptor accessory protein 6 LIN7B 3.336 4.712 5.240 2.848 2.848 2.878 −3.641 0.0321251 lin-7 homolog B (C. elegans) GGA1 8.146 8.029 8.898 7.286 6.165 6.216 −3.641 0.0119386 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 ARRDC2 5.943 7.028 5.958 3.992 4.840 5.164 −3.640 0.0204428 arrestin domain containing 2 IGFBP2 5.604 6.477 5.764 3.900 3.350 5.191 −3.640 0.0232540 insulin-like growth factor binding protein 2, 36 kDa SFRS17A 7.600 5.585 6.703 4.733 5.736 4.548 −3.639 0.0449831 No description C10orf116 8.135 9.034 8.860 6.998 6.886 7.060 −3.637 0.0049363 chromosome 10 open reading frame 116 PABPC1L 6.672 5.753 5.818 3.343 4.594 4.810 −3.636 0.0168880 poly(A) binding protein, cytoplasmic 1−like FLJ45079 5.483 4.952 4.512 2.650 4.382 3.059 −3.635 0.0321520 No description MMP24 3.336 3.758 4.313 1.474 1.692 3.304 −3.634 0.0366884 matrix metallopeptidase 24 (membrane-inserted) TMEM93 3.966 3.966 3.616 −0.026 2.105 3.152 −3.631 0.0409662 transmembrane protein 93 FAM40A 4.784 5.707 4.305 2.296 3.847 3.680 −3.630 0.0355940 family with sequence similarity 40, member A PSMA2 7.376 6.925 5.726 4.296 5.518 4.946 −3.626 0.0252686 proteasome (prosome, macropain) subunit, alpha type, 2 LOC440957 6.216 6.364 6.349 4.282 4.507 4.493 −3.621 0.0004129 No description CILP2 3.220 4.098 4.230 1.974 2.377 1.974 −3.612 0.0073162 cartilage intermediate layer protein 2 SHCBP1 8.575 9.402 7.374 6.511 6.722 7.335 −3.612 0.0398803 SHC SH2-domain binding protein 1 TEX10 6.408 7.026 6.849 4.396 5.204 4.996 −3.611 0.0036416 testis expressed 10 DEF6 4.801 4.730 4.321 2.404 3.758 2.878 −3.609 0.0154091 differentially expressed in FDCP 6 homolog (mouse) HSPB8 5.154 6.888 6.830 4.384 4.005 5.038 −3.605 0.0260698 heat shock 22 kDa protein 8 GUK1 9.605 9.412 8.436 7.114 7.562 7.661 −3.605 0.0108350 guanylate kinase 1 ZBTB48 5.138 6.974 6.411 4.241 4.562 4.697 −3.603 0.0247506 zinc finger and BTB domain containing 48 MC1R 3.810 5.724 4.685 2.746 2.840 3.496 −3.593 0.0270990 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) RPS15 7.013 5.864 7.246 4.899 5.404 5.002 −3.584 0.0178289 ribosomal protein S15 EFEMP2 6.875 6.832 7.401 4.998 5.083 5.484 −3.565 0.0024421 EGF-containing fibulin-like extracellular matrix protein 2 NUDT18 2.247 3.304 4.282 1.474 2.402 0.974 −3.553 0.0464467 nudix (nucleoside diphosphate linked moiety X)-type motif 18 C22orf13 7.381 9.435 8.421 6.794 6.592 6.214 −3.552 0.0209071 chromosome 22 open reading frame 13 VEZT 6.196 7.467 5.446 3.983 4.572 4.368 −3.551 0.0148243 vezatin, adherens junctions transmembrane protein PRKCZ 5.747 6.831 7.313 5.008 5.435 4.899 −3.538 0.0260269 protein kinase C, zeta TMEM134 6.993 7.361 8.609 5.614 6.145 5.171 −3.536 0.0132755 transmembrane protein 134 TRIP6 8.946 9.571 10.211 7.751 7.952 7.466 −3.532 0.0077345 thyroid hormone receptor interactor 6 HLA-F 12.395 13.578 13.929 12.360 11.762 9.468 −3.523 0.0473147 major histocompatibility complex, class I, F AGR2 4.126 7.026 4.375 2.559 3.204 2.559 −3.520 0.0268619 anterior gradient homolog 2 (Xenopus laevis) PILRB 5.908 7.514 7.077 4.615 5.264 5.495 −3.515 0.0217498 paired immunoglobin-like type 2 receptor beta ATP1B1 8.445 8.506 7.054 6.695 6.405 6.219 −3.510 0.0236792 ATPase, Na+/K+ transporting, beta 1 polypeptide ZNF580 6.259 6.256 5.921 4.900 4.446 3.922 −3.506 0.0055503 zinc finger protein 580 U2AF2 9.118 9.357 10.284 7.310 8.130 7.984 −3.503 0.0113223 U2 small nuclear RNA auxiliary factor 2 PROP 3.364 5.185 4.435 3.343 2.627 2.296 −3.501 0.0379463 prolylcarboxypeptidase (angiotensinase C) SPINT1 9.945 10.590 9.734 8.541 8.025 8.139 −3.496 0.0039916 serine peptidase inhibitor, Kunitz type 1 POLR1E 7.318 6.850 6.433 4.628 5.158 5.412 −3.494 0.0062632 polymerase (RNA) I polypeptide E, 53 kDa RBM3 8.407 8.626 7.582 5.251 6.603 6.914 −3.491 0.0172379 RNA binding motif (RNP1, RRM) protein 3 PKN3 5.642 6.088 5.943 4.997 4.140 3.173 −3.490 0.0183538 protein kinase N3 NARFL 3.728 5.583 4.777 3.117 2.974 2.974 −3.488 0.0226685 nuclear prelamin A recognition factor-like UBAC2 4.360 4.414 3.591 2.559 2.559 2.559 −3.484 0.0064014 UBA domain containing 2 ZFPL1 6.120 6.849 6.345 5.052 4.811 4.296 −3.476 0.0058542 zinc finger protein-like 1 CCDC104 5.237 5.159 4.347 3.187 3.187 3.440 −3.475 0.0065894 coiled-coil domain containing 104 RHOA 11.818 12.120 11.800 9.937 10.323 10.172 −3.475 0.0013024 ras homolog gene family, member A GDPD3 5.451 5.475 6.742 3.659 3.922 4.062 −3.462 0.0074766 glycerophosphodiester phosphodiesterase domain containing 3 GRASP 4.486 5.210 6.343 3.784 3.697 2.695 −3.461 0.0200913 GRP1 (general receptor for phosphoinositides 1)- associated scaffold protein BAP1 7.391 8.891 8.436 6.654 6.969 6.560 −3.441 0.0227744 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) DSC2 9.583 9.334 7.924 7.190 7.485 7.803 −3.436 0.0380929 desmocollin 2 ZW10 4.360 5.899 5.475 3.591 3.476 4.126 −3.417 0.0272809 ZW10, kinetochore associated, homolog (Drosophila) SUSD2 4.631 5.112 5.872 3.343 3.469 3.043 −3.408 0.0060760 sushi domain containing 2 MYO9B 7.816 7.124 7.900 5.760 6.132 6.010 −3.405 0.0051320 myosin IXB TSTD1 7.446 8.051 7.504 5.806 6.286 5.627 −3.399 0.0041719 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 APH1B 5.604 6.520 6.455 4.757 4.415 4.179 −3.394 0.0069731 anterior pharynx defective 1 homolog B (C. elegans) SEMA3G 5.896 4.322 4.548 2.559 2.559 4.255 −3.393 0.0390476 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G UQCRQ 6.840 7.017 6.240 4.478 5.607 4.998 −3.393 0.0118634 ubiquinol-cytochrome c reductase, complex III subunitVIl, 9.5 kDa PPP2R1A 9.168 10.979 9.886 8.335 8.126 7.890 −3.387 0.0148565 protein phosphatase 2, regulatory subunit A, alpha LOC729176 2.671 2.671 1.734 −0.026 1.169 −0.026 −3.386 0.0106639 No description HAG HL 2.944 4.054 4.187 2.296 2.296 2.296 −3.381 0.0198442 hydroxyacylglutathione hydrolase-like DDOST 5.346 7.436 5.473 4.111 3.591 4.368 −3.375 0.0215157 dolichyl-diphosphooligosaccharide-protein glycosyltransferase TRIM45 3.758 2.531 3.922 0.974 2.169 0.974 −3.371 0.0143845 tripartite motif-containing 45 CDC42BPB 7.030 8.604 7.871 5.913 6.101 6.851 −3.369 0.0298327 CDC42 binding protein kinase beta (DMPK-like) TP53TG1 5.772 5.577 5.348 4.118 3.825 2.108 −3.369 0.0127705 TP53 target 1 (non-protein coding) DMAP1 6.796 7.406 8.211 6.461 5.557 5.484 −3.363 0.0222625 DNA methyltransferase 1 associated protein 1 CAPN8 8.910 10.880 8.918 7.493 7.957 7.162 −3.359 0.0211612 calpain 8 GYLTL1B 4.042 3.468 4.875 2.296 2.296 2.695 −3.354 0.0130008 glycosyltransferase-like 1B S100A14 12.917 13.609 13.796 11.646 12.054 11.190 −3.346 0.0071167 S100 calcium binding protein A14 MTMR11 5.768 6.118 5.488 4.637 4.027 3.680 −3.344 0.0080913 myotubularin related protein 11 RNASET2 8.650 8.533 10.916 6.793 7.668 7.889 −3.340 0.0425295 ribonuclease T2 NUCB2 7.284 8.411 6.658 5.624 5.546 5.464 −3.335 0.0129555 nucleobindin 2 EGFL8 4.360 4.577 5.475 2.746 2.840 3.205 −3.333 0.0062057 EGF-like-domain, multiples STX3 7.520 7.227 6.186 5.336 5.440 5.784 −3.331 0.0218772 syntaxin 3 C22orf28 7.241 6.234 5.394 4.290 4.990 4.498 −3.331 0.0249731 chromosome 22 open reading frame 28 KCNAB3 4.421 5.510 5.070 3.334 4.448 2.457 −3.330 0.0433784 potassium voltage-gated channel, shaker-related subfamily, beta member 3 MAGOH 7.842 7.479 9.693 5.744 7.078 6.844 −3.330 0.0469271 mago-nashi homolog, proliferation-associated (Drosophila) ZNF238 5.819 5.657 5.189 4.085 3.858 3.839 −3.328 0.0031857 zinc finger protein 238 MOGS 5.920 6.640 6.764 4.434 4.960 4.907 −3.323 0.0067966 mannosyl-oligosaccharide glucosidase ATAD3B 5.072 5.578 6.616 3.343 4.394 4.522 −3.316 0.0281504 ATPase family, AAA domain containing 3B NFKBIL1 5.275 5.262 5.633 3.511 3.548 4.459 −3.310 0.0105863 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 HCFC1 7.083 8.841 8.171 6.450 6.192 6.650 −3.298 0.0254213 host cell factor C1 (VP16-accessory protein) DBNDD1 6.520 8.441 8.257 6.721 6.037 5.484 −3.295 0.0446777 dysbindin (dystrobrevin binding protein 1) domain containing 1 AMT 6.643 5.533 6.546 4.054 3.817 5.829 −3.287 0.0460829 aminomethyltransferase AQP3 6.223 9.404 7.127 5.069 5.412 5.844 −3.284 0.0418580 aquaporin 3 (Gill blood group) WBP1 7.370 7.525 7.882 5.657 6.029 5.981 −3.278 0.0022863 WW domain binding protein 1 SNRNP35 4.204 4.976 4.864 3.263 3.123 2.695 −3.278 0.0062955 small nuclear ribonucleoprotein 35 kDa (U11/U12) LOC93622 4.042 5.560 5.299 3.848 3.248 3.043 −3.278 0.0260061 No description MTATP6 12.461 13.249 11.341 10.448 10.749 10.880 −3.276 0.0263998 No description SLC39A4 5.418 5.630 6.367 3.542 4.657 4.646 −3.271 0.0229325 solute carrier family 39 (zinc transporter), member 4 KIAA0922 5.529 4.336 3.126 2.296 2.627 3.043 −3.268 0.0459309 KIAA0922 LOC139201 5.418 4.857 4.382 2.108 3.825 3.152 −3.260 0.0189816 No description NUP160 4.514 5.457 5.136 3.205 3.648 3.431 −3.260 0.0079156 nucleoporin 160 kDa CCDC53 4.353 4.005 3.240 1.911 1.559 2.650 −3.257 0.0116094 coiled-coil domain containing 53 PHF23 5.083 5.985 5.616 3.381 3.680 4.891 −3.255 0.0268726 PHD finger protein 23 DTX2 6.906 7.902 7.101 5.168 6.249 5.400 −3.252 0.0143108 deltex homolog 2 (Drosophila) MCAT 6.098 7.146 7.575 5.776 5.445 5.164 −3.250 0.0261190 malonyl CoA:ACP acyltransferase (mitochondrial) RILPL2 4.349 3.891 2.875 1.559 1.559 2.650 −3.247 0.0205457 Rab interacting lysosomal protein-like 2 KHSRP 7.942 7.734 7.277 6.036 6.034 6.218 −3.245 0.0038956 KH-type splicing regulatory protein MMP14 4.987 6.276 5.817 4.400 4.121 3.831 −3.241 0.0153661 matrix metallopeptidase 14 (membrane-inserted) ETNK2 6.978 5.258 4.423 3.643 3.565 3.443 −3.233 0.0275526 ethanolamine kinase 2 TLCD1 3.470 3.604 2.453 1.911 1.559 1.559 −3.233 0.0157160 TLC domain containing 1 CHKB 6.001 6.835 6.286 3.664 4.593 5.462 −3.232 0.0203653 choline kinase beta RPSAP58 12.692 12.206 11.701 9.495 10.631 11.001 −3.230 0.0165127 ribosomal protein SA pseudogene 58 SBF1P1 10.300 9.473 9.980 7.647 8.620 8.291 −3.224 0.0089747 SET binding factor 1 pseudogene 1 CEACAM19 6.203 7.654 8.265 4.926 5.998 5.965 −3.223 0.0375180 carcinoembryonic antigen-related cell adhesion molecule 19 UBXN1 8.964 9.183 9.244 7.495 7.213 7.873 −3.222 0.0034474 UBX domain protein 1 GPR108 7.417 8.575 8.837 6.888 7.022 6.694 −3.221 0.0273615 G protein-coupled receptor 108 ALDH4A1 6.059 6.387 8.108 4.920 5.160 4.372 −3.221 0.0199002 aldehyde dehydrogenase 4 family, member A1 CDK20 3.810 4.323 4.247 2.559 2.559 2.559 −3.221 0.0024804 cyclin-dependent kinase 20 TBC1D10B 5.924 6.312 6.510 4.237 5.281 4.462 −3.219 0.0114052 TBC1 domain family, member 10B ZBTB22 4.964 5.735 5.802 3.585 4.116 3.888 −3.218 0.0074981 zinc finger and BTB domain containing 22 NAPA 8.693 10.011 8.597 7.280 7.170 6.916 −3.206 0.0090844 N-ethylmaleimide-sensitive factor attachment protein, alpha UBR4 9.432 9.744 9.597 7.901 8.177 7.754 −3.200 0.0017767 ubiquitin protein ligase E3 component n-recognin 4 PUF60 7.502 8.989 8.892 6.636 7.278 7.214 −3.199 0.0375395 poly-U binding splicing factor 60KDa TICAM1 8.103 8.344 7.666 6.353 6.129 6.668 −3.197 0.0044566 toll-like receptor adaptor molecule 1 CRIP2 9.331 9.214 8.900 6.680 7.677 7.538 −3.195 0.0051489 cysteine-rich protein 2 INO80B 6.289 5.144 6.371 3.469 4.821 4.246 −3.193 0.0207859 INO80 complex subunit B CDK5RAP3 6.947 5.258 4.231 2.825 3.583 4.222 −3.193 0.0466608 CDK5 regulatory subunit associated protein 3 FPGS 6.547 7.094 6.929 5.213 5.269 5.258 −3.184 0.0022218 folylpolyglutamate synthase SNX17 4.870 4.590 5.354 3.059 3.648 3.205 −3.171 0.0061274 sorting nexin 17 C7orf53 4.870 4.255 3.914 2.559 2.559 3.205 −3.171 0.0112901 chromosome 7 open reading frame 53 C11orf68 9.185 7.994 9.404 6.555 7.521 7.612 −3.170 0.0262709 chromosome 11 open reading frame 68 FKBP11 8.150 9.389 9.594 7.754 7.625 7.726 −3.167 0.0332893 FK506 binding protein 11. 19 kDa NUDT1 5.012 5.478 6.412 3.187 4.382 4.755 −3.154 0.0441719 nudix (nucleoside diphosphate linked moiety X)-type motif 1 ZNF408 5.206 6.159 7.715 4.640 4.503 4.042 −3.151 0.0294129 zinc finger protein 408 MIA 6.514 6.488 7.236 3.825 5.581 5.352 −3.150 0.0217283 melanoma inhibitory activity LRRFIP2 10.949 10.688 10.911 8.775 9.259 9.902 −3.143 0.0111673 leucine rich repeat (in FLU) interacting protein 2 C11orf59 4.915 6.179 5.122 4.295 4.397 3.263 −3.142 0.0389908 chromosome 11 open reading frame 59 IL17RD 4.918 6.162 5.267 3.327 4.434 3.616 −3.140 0.0196216 interleukin 17 receptor D SLC16A5 4.215 5.514 4.457 3.868 3.196 2.457 −3.130 0.0335963 solute carrier family 16, member 5 (monocarboxylic acid transporter 6) ARL4A 5.127 3.719 4.705 3.459 2.648 3.059 −3.129 0.0279133 ADP-ribosylation factor-like 4A NIT2 7.239 7.932 7.559 5.441 6.287 6.087 −3.127 0.0083154 nitrilase family, member 2 TXNDC11 5.121 5.223 3.802 3.578 2.840 2.899 −3.126 0.0234198 thioredoxin domain containing 11 BARD1 3.475 3.203 2.404 1.559 1.559 1.559 −3.125 0.0121366 BRCA1 associated RING domain 1 ITPA 4.862 4.786 3.836 2.194 3.617 2.602 −3.122 0.0216324 inosine triphosphatase (nucleoside triphosphate pyrophosphatase) PIK3R2 5.138 6.742 3.924 2.559 3.632 3.496 −3.122 0.0386708 phosphoinositide-3-kinase, regulatory subunit 2 (beta) PAPSS1 5.664 6.398 4.665 4.758 3.712 3.954 −3.117 0.0477889 3′-phosphoadenosine 5′-phosphosulfate synthase 1 LIPH 4.267 3.981 3.936 2.296 3.512 2.296 −3.117 0.0267421 lipase, member H FAM65A 7.948 9.749 8.833 7.121 7.196 7.281 −3.110 0.0224697 family with sequence similarity 65, member A AMFR 7.173 8.588 8.509 6.952 5.703 6.168 −3.108 0.0208457 autocrine motility factor receptor GPX7 3.859 4.237 4.568 1.559 3.617 2.602 −3.106 0.0360468 glutathione peroxidase 7 C19orf43 10.031 10.736 10.363 8.401 8.730 8.885 −3.103 0.0038158 chromosome 19 open reading frame 43 ACAD10 5.443 5.206 5.613 3.809 3.343 4.042 −3.103 0.0035434 acyl-CoA dehydrogenase family, member 10 CAPN1 8.999 10.888 9.513 8.342 7.880 7.544 −3.102 0.0202947 calpain 1, (mu/l) large subunit RCVRN 2.247 3.324 3.021 0.974 1.692 0.974 −3.101 0.0124129 recoverin SF4 3.878 5.076 3.968 2.246 3.383 3.220 −3.099 0.0435925 No description MAPKBP1 7.813 6.819 8.124 5.460 5.626 6.492 −3.098 0.0177306 mitogen-activated protein kinase binding protein 1 PPP2R5C 7.469 6.849 7.292 5.431 5.838 5.565 −3.097 0.0040131 protein phosphatase 2, regulatory subunit B′, gamma TMED2 9.765 10.375 8.460 8.183 7.934 8.136 −3.093 0.0423684 transmembrane emp24 domain trafficking protein 2 TAGLN2 10.227 10.345 9.741 8.717 8.563 8.425 −3.092 0.0040752 transgelin 2 CYFIP2 4.353 3.187 2.404 1.559 2.075 1.559 −3.089 0.0345556 cytoplasmic FMR1 interacting protein 2 E2F5 3.859 4.137 3.186 1.559 2.648 1.559 −3.088 0.0121558 E2F transcription factor 5, p130-binding DDB1 8.015 8.884 8.882 6.935 7.249 7.258 −3.087 0.0117183 damage-specific DNA binding protein 1, 127 kDa SF3B5 10.031 10.315 10.250 8.406 9.075 8.625 −3.086 0.0049616 splicing factor 3b, subunit 5, 10 kDa CTBS 6.060 6.339 6.470 4.846 4.503 4.650 −3.083 0.0019870 chitobiase, di-N-acetyl- MAPK8IP3 8.376 9.226 9.773 7.603 7.431 7.948 −3.081 0.0223937 mitogen-activated protein kinase 8 interacting protein 3 C8orf45 2.878 3.097 2.404 1.474 0.974 0.974 −3.080 0.0048772 chromosome 8 open reading frame 45 NUMBL 5.564 4.844 6.513 3.913 3.716 4.891 −3.078 0.0464106 numb homolog (Drosophila)-like MKI67IP 4.984 6.425 6.500 3.459 4.879 4.144 −3.076 0.0261397 MKI67 (FHA domain) interacting nucleolar phosphoprotein COPE 8.204 9.381 8.678 7.064 7.206 6.585 −3.073 0.0085756 coatomer protein complex, subunit epsilon PNP 9.193 8.805 8.913 7.185 7.294 7.969 −3.072 0.0084482 purine nucleoside phosphorylase MIB2 7.936 7.427 9.656 6.318 6.157 6.318 −3.070 0.0184451 mindbomb homolog 2 (Drosophila) ZNF32 4.382 5.775 5.577 3.542 3.345 4.158 −3.067 0.0241474 zinc finger protein 32 TIMM10 6.694 6.670 6.262 4.938 5.197 4.646 −3.065 0.0034367 translocase of inner mitochondrial membrane 10 homolog (yeast) NUMA1 9.200 9.814 9.188 7.728 7.573 8.099 −3.064 0.0053484 nuclear mitotic apparatus protein 1 CUL7 5.390 6.419 6.232 4.357 4.618 4.618 −3.061 0.0121857 cullin 7 KLHL17 4.843 4.756 6.261 3.605 3.144 4.066 −3.056 0.0238864 kelch-like 17 (Drosophila) LNX2 4.350 5.893 4.962 3.598 3.026 3.351 −3.054 0.0149624 ligand of numb-protein X 2 EIF2C2 7.151 7.497 7.540 5.540 5.695 6.372 −3.054 0.0083369 eukaryotic translation initiation factor 2C, 2 BANF1 7.852 8.636 8.460 6.906 6.850 6.814 −3.053 0.0069394 barrier to autointegration factor 1 PPP1R15A 8.236 7.612 7.788 5.308 6.179 7.137 −3.050 0.0250522 protein phosphatase 1, regulatory (inhibitor) subunit 15A TRPT1 4.215 3.593 3.583 2.649 1.974 1.974 −3.049 0.0081980 tRNA phosphotransferase 1 STK36 4.741 4.959 3.999 2.943 3.026 3.351 −3.047 0.0118526 serine/threonine kinase 36 SFRS2 10.342 10.656 10.308 8.085 8.735 9.186 −3.047 0.0064804 No description KDM1A 6.760 7.091 5.441 5.165 5.183 4.901 −3.020 0.0425833 lysine (K)-specific demethylase 1A MRPS30 5.418 5.998 5.197 3.664 3.825 4.283 −3.016 0.0075748 mitochondrial ribosomal protein S30 CDK2 6.188 6.676 6.866 4.202 5.176 5.274 −3.015 0.0111036 cyclin-dependent kinase 2 KIAA0427 7.060 8.296 8.845 6.536 6.871 6.705 −3.013 0.0453799 KIAA0427 BUD31 4.572 5.587 4.449 2.860 3.196 3.565 −3.010 0.0129900 BUD31 homolog (S. cerevisiae) NOP14 5.869 6.411 6.544 4.032 4.827 5.369 −2.999 0.0196792 NOP14 nucleolar protein homolog (yeast) SIGLEC8 6.405 5.864 5.887 4.186 4.307 5.175 −2.990 0.0140376 sialic acid binding ig-like lectin 8 LMNA 13.446 13.289 13.361 11.788 11.525 12.909 −2.974 0.0336416 lamin A/C ARGLU1 7.191 6.297 5.559 4.150 4.382 5.620 −2.971 0.0393492 arginine and glutamate rich 1 DGCR2 5.915 7.696 7.048 5.478 5.619 5.085 −2.969 0.0348020 DiGeorge syndrome critical region gene 2 DCAF11 6.837 6.151 6.406 5.267 4.822 4.730 −2.968 0.0068181 DDB1 and CUL4 associated factor 11 EDF1 8.973 9.525 9.320 7.620 7.956 7.703 −2.967 0.0038266 endothelial differentiation-related factor 1 ESRP1 5.930 5.003 5.012 3.728 3.738 3.434 −2.967 0.0072778 epithelial splicing regulatory protein 1 RPS18 13.267 13.287 12.296 10.727 11.567 11.873 −2.967 0.0215756 ribosomal protein S18 ABCE1 6.279 7.394 6.066 4.498 5.506 5.205 −2.965 0.0286562 ATP-binding cassette, sub-family E (OABP), member 1 PHYHD1 6.039 6.042 6.513 4.520 4.421 4.946 −2.963 0.0044459 phytanoyl-CoA dioxygenase domain containing 1 CUEDC1 4.126 5.516 3.649 2.559 3.204 2.559 −2.962 0.0304305 CUE domain containing 1 PHRF1 8.019 8.604 9.115 7.038 7.277 6.975 −2.960 0.0123078 PHD and ring finger domains 1 C1orf86 6.708 7.259 7.479 5.127 6.373 5.693 −2.960 0.0241167 chromosome 1 open reading frame 86 B3GALNT1 3.475 3.844 2.703 1.911 2.075 1.559 −2.956 0.0149455 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) AN010 6.422 7.159 7.191 5.825 5.559 4.859 −2.954 0.0153446 anoctamin 10 GGT7 6.056 6.860 7.207 4.367 5.443 5.645 −2.953 0.0274114 gamma-glutamyltransferase 7 TMEM51 7.081 7.424 6.365 5.553 4.804 5.747 −2.952 0.0158787 transmembrane protein 51 ATAD2 5.049 4.573 4.631 3.489 2.896 3.364 −2.949 0.0058051 ATPase family, AAA domain containing 2 GLI4 4.448 3.699 4.716 1.474 3.022 3.156 −2.948 0.0277306 GLI family zinc finger 4 PUM1 6.823 8.383 6.790 5.231 5.363 5.676 −2.946 0.0144981 pumilio homolog 1 (Drosophila) AP2A1 3.831 5.167 4.937 3.496 3.337 3.379 −2.944 0.0365211 adaptor-related protein complex 2, alpha 1 subunit GFOD1 6.372 5.290 4.997 3.872 3.859 3.440 −2.942 0.0104981 glucose-fructose oxidoreductase domain containing 1 CHAD 5.741 3.704 3.531 2.246 2.377 1.974 −2.941 0.0198250 chondroadherin C9orf21 6.489 7.267 6.551 4.998 4.568 6.389 −2.934 0.0478250 chromosome 9 open reading frame 21 BAD 6.108 7.143 7.923 6.066 5.591 5.325 −2.934 0.0472978 BCL2-associated agonist of cell death RPL29 7.233 5.932 6.457 4.905 5.041 4.686 −2.933 0.0114751 ribosomal protein L29 TMEM160 5.908 6.858 7.780 5.693 5.306 4.801 −2.932 0.0355833 transmembrane protein 160 UXT 9.005 8.021 7.377 5.825 6.822 7.102 −2.931 0.0395157 ubiquitously-expressed transcript SNRPD2 8.985 7.968 7.950 6.095 7.065 7.434 −2.930 0.0367506 small nuclear ribonucleoprotein D2 polypeptide 16.5 kDa ELF2 5.128 5.891 4.690 3.271 3.144 4.351 −2.920 0.0219685 E74-like factor 2 (ets domain transcription factor) ACADM 5.607 5.535 6.144 4.730 3.922 4.062 −2.918 0.0100683 acyl-CoA dehydrogenase, C-4 to C-12 straight chain HPCAL1 10.456 9.705 10.801 8.911 9.191 8.764 −2.918 0.0180814 hippocalcin-like 1 RHPN1 7.516 7.334 8.170 5.824 6.278 5.972 −2.917 0.0059079 rhophilin, Rho GTPase binding protein 1 FEZ2 6.793 7.518 7.168 5.099 6.065 5.626 −2.912 0.0112464 fasciculation and elongation protein zeta 2 (zygin ll) P4HB 11.496 12.143 10.817 10.442 9.955 9.432 −2.911 0.0232978 prolyl 4-hydroxylase, beta polypeptide MRPL42 7.786 8.213 6.931 6.605 6.246 6.115 −2.909 0.0276163 mitochondrial ribosomal protein L42 LGALS3BP 5.593 6.805 6.004 4.465 4.675 4.226 −2.906 0.0103008 lectin, galactoside-binding, soluble, 3 binding protein RBM12 7.481 7.982 7.202 4.973 6.444 6.174 −2.904 0.0190307 RNA binding motif protein 12 PBX2 8.125 8.698 8.764 7.227 6.817 7.097 −2.902 0.0063438 pre-B-cell leukemia homeobox 2 NDUFB7 6.529 7.105 7.060 5.523 5.927 4.736 −2.901 0.0167636 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18 kDa HNRNPUL2 4.071 5.248 5.066 3.532 3.648 3.205 −2.896 0.0247114 heterogeneous nuclear ribonucleoprotein U-like2 ZDHHC24 5.309 6.068 6.603 5.070 4.892 3.220 −2.894 0.0487383 zinc finger, DHHC-type containing 24 UBE2A 4.280 4.986 4.505 2.974 3.190 2.974 −2.888 0.0045426 ubiquitin-conjugating enzyme E2A(RAD6 homolog) SMPDL3B 3.336 4.167 3.932 3.022 2.402 0.974 −2.888 0.0359010 sphingomyelin phosphodiesterase, acid-like 3B TMX2 5.537 7.083 5.013 4.190 4.266 3.484 −2.887 0.0244835 thioredoxin-related transmembrane protein 2 RAP1GAP 6.822 6.002 7.387 4.486 5.292 5.688 −2.886 0.0272701 RAP1 GTPase activating protein CCND1 8.435 10.020 8.525 7.252 7.548 6.907 −2.885 0.0197629 cyclin D1 TMEM101 6.458 7.445 7.219 4.957 5.917 5.016 −2.884 0.0118104 transmembrane protein 101 GIPC1 8.995 9.865 8.513 6.987 7.876 7.494 −2.878 0.0167851 GIPC PDZ domain containing family, member 1 ZNF688 4.215 5.258 5.810 3.966 2.692 4.098 −2.875 0.0493507 zinc finger protein 688 ERCC2 5.140 4.455 5.031 3.617 3.296 3.296 −2.874 0.0066454 excision repair cross-complementing rodent repair deficiency, complementation group 2 RAD9A 6.738 7.195 6.138 4.678 5.215 5.643 −2.873 0.0181090 RAD9 homolog A (S. pombe) ALOX15B 9.153 7.845 8.800 7.630 6.579 7.149 −2.873 0.0288127 arachidonate 15-lipoxygenase, type B CAD 6.830 6.996 8.775 5.768 5.474 5.371 −2.872 0.0179440 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase RRBP1 6.938 7.930 6.111 5.420 5.583 5.333 −2.864 0.0288335 ribosome binding protein 1 homolog 180 kDa (dog) VARS2 6.907 8.281 8.179 6.492 6.765 6.547 −2.859 0.0492617 valyl-tRNA synthetase 2, mitochondrial (putative) TMEM5 5.086 4.983 4.766 2.933 3.758 3.469 −2.857 0.0061381 transmembrane protein 5 SFPQ 7.654 9.586 8.607 6.610 7.094 7.295 −2.855 0.0323998 splicing factor proline/glutamine-rich FAM76A 4.218 4.195 3.809 2.518 2.896 2.296 −2.854 0.0050576 family with sequence similarity 76, member A CCNK 6.965 7.450 7.633 6.121 5.897 5.849 −2.853 0.0070215 cyclin K CAPS 4.126 5.386 4.715 3.205 2.840 3.496 −2.848 0.0157790 calcyphosine ZNF581 5.954 6.074 6.133 4.098 4.627 4.584 −2.842 0.0025480 zinc finger protein 581 GLT25D1 5.849 7.879 6.347 4.578 4.840 5.147 −2.841 0.0239279 glycosyltransferase 25 domain containing 1 STOML2 7.074 9.621 7.616 6.110 5.896 6.749 −2.840 0.0436662 stomatin (EPB72)-like 2 EPCAM 6.839 5.966 6.399 4.083 5.333 5.263 −2.840 0.0248757 epithelial cell adhesion molecule ACSF3 6.160 6.782 7.555 5.416 5.278 4.951 −2.836 0.0151596 acyl-CoA synthetase family member 3 CMTM3 8.102 8.899 8.427 6.599 7.127 7.278 −2.835 0.0110614 CKLF-like MARVEL transmembrane domain containing 3 WDR33 6.532 6.825 6.365 4.931 5.030 5.247 −2.833 0.0030798 WD repeat domain 33 CHCHD2 11.669 12.241 13.517 10.739 11.188 10.656 −2.832 0.0295395 coiled-coil-helix-coiled-coil-helix domain containing 2 MSRA 4.421 6.280 5.523 4.421 4.022 3.443 −2.831 0.0494371 methionine sulfoxide reductase A ORMDL1 6.056 6.066 5.016 4.241 4.565 4.367 −2.830 0.0217836 ORM1-like1 (S. cerevisiae) ALKBH5 6.493 6.987 5.796 4.296 4.560 5.551 −2.829 0.0227467 alkB, alkylation repair homolog 5 (E. coli) KIAA1683 4.126 3.637 4.059 2.559 2.559 2.559 −2.828 0.0039601 KIAA1683 OR7E156P 3.059 2.650 5.225 1.559 2.075 1.559 −2.828 0.0393116 olfactory receptor, family 7, subfamily E, member 156 pseudogene GRTP1 4.968 3.922 5.267 3.659 3.022 3.469 −2.826 0.0333952 growth hormone regulated TBC protein 1 STRC 3.954 3.822 2.860 1.974 1.974 2.457 −2.821 0.0195203 stereocilin PPFIBP2 5.055 5.010 4.353 3.319 2.858 3.704 −2.818 0.0116646 PTPRF interacting protein, binding protein 2 (liprin beta 2) ILVBL 6.061 5.072 5.084 3.578 4.347 3.787 −2.816 0.0173154 ilvB (bacterial acetolactate synthase)-like GCAT 3.059 3.051 2.650 1.559 1.559 1.559 −2.812 0.0034259 glycine C-acetyltransferase ECHS1 5.747 5.402 5.851 3.963 4.360 3.954 −2.811 0.0032402 enoyl CoA hydratase, short chain, 1, mitochondrial STBD1 5.604 6.118 6.038 4.111 4.547 5.191 −2.810 0.0218519 starch binding domain 1 STX5 10.164 9.456 10.722 8.675 8.634 8.884 −2.806 0.0201243 syntaxin 5 KIAA0652 6.467 6.440 5.231 4.952 4.537 4.964 −2.806 0.0403822 No description FBP1 6.747 6.473 6.027 5.602 4.985 4.367 −2.805 0.0219071 fructose-1,6-bisphosphatase 1 PSPC1 4.428 5.686 3.774 2.943 3.026 2.782 −2.798 0.0234091 paraspeckle component 1 PRSS22 8.961 9.960 10.401 7.838 8.478 8.859 −2.794 0.0404137 protease, serine, 22 PRMT5 4.548 5.693 4.939 3.178 4.213 3.404 −2.788 0.0255787 protein arginine methyltransferase 5 IMP3 5.575 7.155 5.386 4.548 4.485 3.907 −2.788 0.0259954 IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast) LIG1 4.821 5.125 5.488 3.809 3.343 3.809 −2.785 0.0068074 ligase l, DNA, ATP-dependent CEP290 3.954 3.724 3.724 2.246 2.692 1.974 −2.785 0.0052801 centrosomal protein 290 kDa APOBEC3C 4.801 4.801 4.693 3.324 3.022 3.758 −2.782 0.0069286 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C SH3BGRL 6.314 6.256 4.989 3.992 4.840 4.498 −2.779 0.0346316 SH3 domain binding glutamic acid-rich protein like CDK5RAP2 6.021 6.093 6.775 5.223 4.547 5.124 −2.778 0.0168120 CDK5 regulatory subunit associated protein 2 ING5 5.349 5.694 5.655 3.848 4.820 4.183 −2.776 0.0177091 inhibitor of growth family, member 5 ACSF2 6.639 6.999 7.227 5.527 5.722 5.226 −2.774 0.0059509 acyl-CoA synthetase family member 2 PSME2 6.665 8.477 7.546 5.237 6.626 6.075 −2.773 0.0442095 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) WDR18 5.773 6.860 6.800 5.153 5.390 4.499 −2.772 0.0232433 WD repeat domain 18 SCMH1 4.492 5.277 4.953 2.974 3.483 3.888 −2.771 0.0145088 sex comb on midleg homolog 1 (Drosophila) ZFX 5.035 5.647 4.066 3.565 4.032 2.782 −2.771 0.0444421 zinc finger protein, X-linked EEF1D 11.399 12.560 12.633 10.153 10.518 11.163 −2.769 0.0227360 eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) BEND2 5.012 5.198 6.164 4.154 4.065 3.544 −2.767 0.0162157 BEN domain containing 2 TMED3 7.873 8.104 7.627 6.581 6.336 6.408 −2.761 0.0034689 transmembrane emp24 protein transport domain containing 3 ABCB9 4.408 4.384 3.616 2.943 2.782 2.782 −2.760 0.0131374 ATP-binding cassette, sub-family B (MDR/TAP), member 9 EXOC7 7.761 8.737 9.649 7.274 7.629 6.919 −2.758 0.0451857 exocyst complex component 7 C7orf63 5.745 5.495 4.412 4.116 3.519 4.031 −2.758 0.0342087 chromosome 7 open reading frame 63 RNASEK 10.642 11.328 11.639 9.865 9.900 9.420 −2.757 0.0127813 ribonuclease, RNase K SMARCD2 6.309 7.195 7.181 5.732 5.457 4.980 −2.757 0.0143323 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 CHSY1 7.166 7.434 7.076 5.707 4.933 6.173 −2.749 0.0116454 chondroitin sulfate synthase 1 MPG 7.550 8.392 8.997 6.934 7.182 6.627 −2.748 0.0283070 N-methylpurine-DNA glycosylase SF3A2 8.649 9.024 9.409 7.132 7.580 7.950 −2.748 0.0120230 splicing factor 3a, subunit 2, 66 kDa GCN1L1 6.952 7.480 7.228 5.227 6.332 5.770 −2.747 0.0153983 GCN1 general control of amino-acid synthesis 1−like 1 (yeast) NFRKB 7.430 8.019 8.175 6.319 6.681 6.561 −2.746 0.0101796 nuclear factor related to kappaB binding protein MRPS34 5.692 7.828 6.575 5.673 5.117 4.445 −2.746 0.0491827 mitochondrial ribosomal protein S34 TNF 11.469 10.461 11.873 9.639 10.227 10.012 −2.745 0.0366278 tumor necrosis factor WDR59 6.213 6.439 5.483 4.263 4.866 4.758 −2.741 0.0155157 WD repeat domain 59 ZNF783 4.717 4.922 4.575 3.396 3.187 3.264 −2.738 0.0021320 zinc finger family member 783 TXNDC16 4.353 4.511 3.186 1.911 2.075 3.059 −2.737 0.0240322 thioredoxin domain containing 16 ELMO2 4.292 4.613 4.565 2.911 2.840 3.205 −2.736 0.0027007 engulfment and cell motility 2 NEDD4L 10.390 10.001 9.915 8.063 8.683 8.938 −2.736 0.0087475 neural precursor cell expressed, developmentally down- regulated 4-like FCGRT 7.506 8.310 7.709 6.056 6.339 6.697 −2.733 0.0106262 Fc fragment of IgG, receptor, transporter, alpha MFGE8 12.034 11.230 13.562 9.843 10.584 10.894 −2.732 0.0370123 milk fat globule-EGF factor 8 protein TPD52 7.837 6.755 6.204 5.666 5.223 5.307 −2.729 0.0258473 tumor protein D52 CTTN 9.400 10.709 10.307 8.859 8.773 9.114 −2.728 0.0355510 cortactin CD276 7.569 8.942 8.724 7.276 7.151 7.351 −2.728 0.0496738 CD276 molecule TMC7 6.253 7.131 5.770 5.068 4.808 4.772 −2.723 0.0179954 transmembrane channel-like 7 GRINA 8.175 9.355 8.958 7.457 7.513 7.532 −2.722 0.0200230 glutamate receptor, ionotropic, N-methyl D-aspartate- associated protein 1 (glutamate binding) PPP1R1A 5.028 3.747 4.693 3.108 3.583 3.220 −2.722 0.0409555 protein phosphatase 1, regulatory (inhibitor) subunit 1A ATAD1 6.837 6.422 5.932 4.906 5.225 4.978 −2.722 0.0122655 ATPase family, AAA domain containing 1 KDM4B 5.772 5.669 5.226 3.902 4.226 4.226 −2.719 0.0050982 lysine (K)-specific demethylase 4B TNFAIP1 6.192 6.890 6.889 5.449 5.311 4.900 −2.715 0.0103515 tumor necrosis factor, alpha-induced protein 1 (endothelial) VAMP8 8.553 10.523 8.303 7.078 7.112 7.281 −2.715 0.0244620 vesicle-associated membrane protein 8 (endobrevin) B3GALT6 6.136 7.427 7.180 5.882 5.739 5.554 −2.714 0.0401535 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 SLC27A1 6.028 6.093 5.574 4.396 4.732 4.134 −2.714 0.0064996 solute carrier family 27 (fatty acid transporter), member 1 ENSA 7.270 7.060 6.778 5.339 5.630 5.690 −2.711 0.0037383 endosulfine alpha ANKK1 7.705 7.572 6.644 6.087 6.110 6.266 −2.710 0.0312840 ankyrin repeat and kinase domain containing 1 STK10 5.224 7.055 6.160 4.571 4.835 4.722 −2.710 0.0377544 serine/threonine kinase 10 ABTI 5.642 7.363 6.122 4.686 4.486 4.859 −2.707 0.0201635 activator of basal transcription 1 TRAFD1 9.334 9.337 8.105 7.901 7.575 7.586 −2.707 0.0381381 TRAF-type zinc finger domain containing 1 ZBTB47 4.419 6.026 5.506 4.070 4.148 3.509 −2.706 0.0373438 zinc finger and BTB domain containing 47 NCAPH2 8.138 8.038 8.725 5.798 6.702 7.294 −2.705 0.0167130 non-SMC condensin II complex, subunit H2 TMEM214 7.649 8.394 8.147 6.530 6.960 6.586 −2.701 0.0102195 transmembrane protein 214 INPPL1 8.541 9.613 8.552 7.384 7.109 7.173 −2.698 0.0094520 inositol polyphosphate phosphatase-like 1 PLA2G2D 7.947 7.834 7.092 6.194 6.404 6.455 −2.696 0.0154482 phospholipase A2, group HD LOC1002332 7.606 7.749 7.351 6.228 5.920 6.293 −2.695 0.0038534 No description 09 CDH1 11.665 11.560 10.986 9.795 10.187 10.130 −2.695 0.0093745 cadherin 1, type 1, E-cadherin (epithelial) TSPAN4 5.309 5.651 6.938 4.165 4.222 4.758 −2.693 0.0264375 tetraspanin 4 XRCC1 4.572 5.887 5.527 4.459 3.583 3.954 −2.690 0.0367813 X-ray repair complementing defective repair in Chinese hamster cells 1 DDAH2 10.278 10.190 11.039 9.085 8.763 8.893 −2.688 0.0070107 dimethylarginine dimethylaminohydrolase 2 PRDX2 7.848 7.891 7.240 6.026 6.465 5.875 −2.687 0.0075579 peroxiredoxin 2 PDK2 4.793 5.019 5.305 3.880 3.638 3.236 −2.685 0.0070959 pyruvate dehydrogenase kinase, isozyme 2 ELF3 10.236 9.851 9.027 8.051 8.237 8.814 −2.680 0.0294021 E74-like factor 3 (ets domain transcription factor, epithelial- specific ) GJC2 3.220 3.668 4.383 2.246 1.974 2.860 −2.680 0.0256815 gap junction protein, gamma 2, 47 kDa PRDM2 7.555 7.658 6.965 5.927 6.135 6.219 −2.676 0.0104774 PR domain containing 2, with ZNF domain ZNF250 6.682 6.005 5.958 4.540 4.547 5.673 −2.673 0.0361351 zinc finger protein 250 SLC25A6 12.433 12.029 12.023 10.365 11.015 11.001 −2.672 0.0100476 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 CYB561D2 5.097 6.528 5.187 4.486 4.594 3.680 −2.670 0.0482671 cytochrome b-561 domain containing 2 FAM36A 6.702 6.347 5.653 5.181 4.922 4.931 −2.669 0.0226915 family with sequence similarity 36, member A KRH 4.126 4.620 3.257 2.559 3.204 2.559 −2.668 0.0448243 KRH homolog (S. cerevisiae) CBY1 6.204 7.413 6.824 5.747 5.410 5.394 −2.665 0.0242180 chibby homolog 1 (Drosophila) RPL27 9.780 9.760 8.555 7.533 7.639 8.366 −2.664 0.0248258 ribosomal protein L27 CYB5RL 7.092 6.868 6.282 5.454 5.135 5.651 −2.664 0.0135994 cytochrome b5 reductase-like COMMD6 9.982 8.919 9.040 7.510 7.917 8.277 −2.656 0.0216216 COMM domain containing 6 ZNF204P 3.706 4.074 3.387 2.296 2.296 2.296 −2.656 0.0052525 zinc finger protein 204, pseudogene C8orf58 3.706 4.179 4.187 3.043 2.296 2.695 −2.656 0.0117437 chromosome 8 open reading frame 58 IL11 3.706 3.798 4.749 3.013 2.296 3.043 −2.656 0.0307107 interleukin 11 KIAA0895 4.631 5.225 5.571 2.709 3.817 4.445 −2.654 0.0400223 KIAA0895 PLA2G2A 2.878 2.878 1.643 1.474 0.974 0.974 −2.646 0.0335065 phospholipase A2, group HA (platelets, synovial fluid) LRPAP1 2.878 4.766 3.772 1.474 2.848 2.404 −2.646 0.0490384 low density lipoprotein receptor-related protein associated protein 1 VEGFB 6.204 6.044 5.355 4.907 3.469 4.641 −2.644 0.0278849 vascular endothelial growth factor B POLR2G 6.927 7.637 6.118 5.720 5.525 5.107 −2.643 0.0287137 polymerase (RNA) II (DNA directed) polypeptide G DIS3L 9.815 9.807 9.212 8.138 8.092 8.414 −2.641 0.0074873 DIS3 mitotic control homolog (S. cerevisiae)-like ULK3 5.443 5.619 4.997 4.054 4.042 4.042 −2.640 0.0069501 unc-51-like kinase 3 (C. elegans) SCARB2 6.571 5.922 4.927 4.835 4.210 4.525 −2.634 0.0497598 scavenger receptor class B, member 2 PM20D2 5.109 5.892 4.977 4.107 3.877 3.581 −2.631 0.0122341 peptidase M20 domain containing 2 C14orf1 3.470 4.585 2.875 2.610 2.075 1.559 −2.630 0.0352264 chromosome 14 open reading frame 1 CLDN3 11.944 10.306 11.121 9.727 9.806 9.551 −2.628 0.0303384 claudin 3 TRIM28 10.809 11.225 11.774 9.518 9.831 9.994 −2.628 0.0108135 tripartite motif-containing 28 TSPAN9 4.607 4.642 5.608 4.215 3.704 3.077 −2.626 0.0403715 tetraspanin 9 EIF4EBP1 8.458 9.158 8.062 7.474 7.066 6.722 −2.624 0.0173569 eukaryotic translation initiation factor 4E binding protein 1 DCUN1D2 4.741 4.912 6.004 3.692 4.005 3.351 −2.620 0.0193929 DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae) GRK6 6.799 7.415 8.167 5.918 6.027 6.118 −2.617 0.0200476 G protein-coupled receptor kinase 6 PTPRF 9.737 10.180 10.451 8.793 8.178 9.201 −2.614 0.0181366 protein tyrosine phosphatase, receptor type, F ICA1 8.614 8.797 9.800 7.505 8.159 7.229 −2.612 0.0269808 islet cell autoantigen 1,69 kDa ABHD14A 3.059 3.767 3.459 1.911 2.075 2.173 −2.611 0.0077130 abhydrolase domain containing 14A ZNF667 4.042 3.680 3.364 2.296 2.627 2.296 −2.610 0.0101389 zinc finger protein 667 ARL8A 9.097 10.373 9.717 8.222 8.333 8.544 −2.609 0.0218243 ADP-ribosylation factor-like 8A ENGASE 6.178 7.262 8.371 5.056 5.900 5.879 −2.609 0.0420706 endo-beta-N-acetylglucosaminidase HIGD2A 7.281 6.431 7.542 5.861 5.482 6.160 −2.607 0.0309355 HIG1 hypoxia inducible domain family, member 2A HNRNPAO 7.663 9.014 7.607 6.225 6.701 7.043 −2.607 0.0352371 heterogeneous nuclear ribonucleoprotein AO LOCI 002943 8.693 8.282 8.656 7.275 6.749 7.705 −2.604 0.0168772 No description 62 CBX6 4.585 5.018 4.455 3.205 3.960 2.782 −2.603 0.0218350 chromobox homolog 6 SLC37A3 6.809 7.304 6.114 4.859 4.737 6.013 −2.597 0.0297744 solute carrier family 37 (glycerol-3-phosphate transporter), member 3 ATP6AP1 7.260 7.831 7.843 5.955 6.466 5.962 −2.597 0.0067859 ATPase, H+ transporting, lysosomal accessory protein 1 TNPO2 6.912 8.536 7.232 5.977 5.856 5.606 −2.595 0.0170860 transportin 2 RPL36 15.870 15.207 15.070 13.740 13.833 14.164 −2.591 0.0091405 ribosomal protein L36 THAP1 2.247 3.799 2.348 0.974 0.974 0.974 −2.591 0.0142556 THAP domain containing, apoptosis associated protein 1 RECQL5 9.296 9.275 8.466 7.779 7.702 7.924 −2.589 0.0186301 RecQ protein-like 5 MAGH 7.339 6.251 6.337 5.564 4.879 5.793 −2.588 0.0426608 membrane associated guanylate kinase, WW and PDZ domain containing 1 HDAC10 7.716 6.560 8.016 5.898 6.645 5.413 −2.587 0.0426992 histone deacetylase 10 ACSL3 6.935 6.505 5.683 4.326 5.301 5.135 −2.585 0.0279916 acyl-CoA synthetase long-chain family member 3 CLDND1 8.068 9.012 8.194 6.123 7.108 7.643 −2.582 0.0354612 claudin domain containing 1 FLJ35220 3.728 5.094 4.557 2.974 2.974 3.728 −2.578 0.0474171 No description LGALS1 8.272 7.357 7.070 6.121 5.720 5.991 −2.578 0.0117997 lectin, galactoside-binding, soluble, 1 DCAF8 6.777 7.264 6.563 4.274 5.416 6.174 −2.568 0.0345042 DDB1 and CUL4 associated factor 8 CRYZL1 3.220 4.665 3.334 1.974 1.974 1.974 −2.566 0.0134873 crystallin, zeta (quinone reductase)-like 1 ZNF12 5.954 6.242 5.318 4.168 3.962 5.087 −2.560 0.0250115 zinc finger protein 12 SPTAN1 6.820 7.268 7.155 5.800 5.400 6.258 −2.559 0.0161097 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) CIAO1 7.742 7.700 6.943 5.864 5.674 6.387 −2.559 0.0126930 cytosolic iron-sulfur protein assembly 1 CCDC106 3.593 5.309 5.167 2.860 2.377 3.954 −2.558 0.0496447 coiled-coil domain containing 106 NRAS 6.667 8.772 6.811 6.339 5.386 5.456 −2.558 0.0471957 neuroblastoma RAS viral (v-ras) oncogene homolog RHOG 8.266 8.767 8.172 6.817 7.413 7.136 −2.557 0.0128327 ras homolog gene family, member G (rho G) GSTP1 10.005 11.863 10.764 9.412 9.486 9.061 −2.553 0.0312663 glutathione S-transferase pi 1 HNRNPUL1 6.793 6.829 5.740 4.681 5.479 4.860 −2.549 0.0229432 heterogeneous nuclear ribonucleoprotein U-like 1 SF3B14 6.655 7.471 6.354 5.020 5.306 5.635 −2.547 0.0151704 No description PFKL 10.207 10.387 10.923 8.859 9.065 9.125 −2.546 0.0057452 phosphofructokinase, liver ACTR10 5.197 4.844 4.601 3.396 3.496 3.659 −2.545 0.0059187 actin-related protein 10 homolog (S. cerevisiae) BMPS 4.946 4.354 3.745 3.404 2.627 3.007 −2.544 0.0278089 bone morphogenetic protein 3 EEPD1 4.910 3.531 4.457 2.246 2.377 3.565 −2.539 0.0344774 endonuclease/exonuclease/phosphatase family domain containing 1 RING1 9.981 9.558 9.333 7.989 8.611 8.586 −2.538 0.0174566 ring finger protein 1 C17orf28 8.631 8.961 9.258 7.877 7.920 7.267 −2.527 0.0157682 chromosome 17 open reading frame 28 MTMR14 4.991 4.882 3.896 2.559 3.802 3.496 −2.525 0.0470660 myotubularin related protein 14 THBS3 7.106 6.222 8.087 5.977 5.506 5.770 −2.524 0.0461972 thrombospondin 3 ZHX1 5.052 5.225 4.744 3.717 3.716 3.509 −2.524 0.0044075 zinc fingers and homeoboxes 1 B9D2 4.042 4.091 3.962 3.697 2.627 2.695 −2.522 0.0484528 B9 protein domain 2 RABI 7 6.906 7.980 8.257 7.185 5.645 5.571 −2.522 0.0456339 RAB17, member RAS oncogene family PSMC4 6.422 7.995 6.236 4.902 5.661 5.356 −2.521 0.0360683 proteasome (prosome, macropain) 26S subunit, ATPase, 4 PABPC4 7.460 9.108 7.751 6.126 6.808 6.924 −2.521 0.0382471 poly(A) binding protein, cytoplasmic 4 (inducible form) NDUFB3 2.247 2.404 3.021 0.974 1.692 0.974 −2.513 0.0179279 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12 kDa ZDHHC7 9.309 9.784 9.435 8.039 8.456 8.054 −2.511 0.0073615 zinc finger, DHHC-type containing 7 REST 3.706 5.296 3.624 3.043 2.296 2.695 −2.510 0.0375794 RE1-silencing transcription factor UQCR11 8.828 8.252 10.342 7.457 7.918 7.500 −2.509 0.0473354 ubiquinol-cytochrome c reductase, complex III subunit XI C1orf210 5.286 4.583 4.397 2.943 3.960 3.789 −2.506 0.0413937 chromosome 1 open reading frame 210 PPM1G 9.649 10.197 10.745 8.872 8.930 8.633 −2.505 0.0154589 protein phosphatase, Mg2+/Mn2+ dependent, 1G METTL12 4.282 3.304 3.727 2.404 2.402 2.878 −2.502 0.0242625 methyltransferase like 12 CTR9 6.135 6.822 5.464 4.675 4.812 5.191 −2.502 0.0368726 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) USP7 8.300 9.666 9.538 7.269 7.677 8.346 −2.496 0.0411888 ubiquitin specific peptidase 7 (herpes virus-associated) TIMM50 6.938 8.432 6.958 5.692 6.173 5.620 −2.494 0.0240967 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) TMEM184A 7.266 7.131 8.352 5.975 5.947 5.872 −2.494 0.0114896 transmembrane protein 184A ECHI 6.207 6.046 5.455 4.138 4.665 5.036 −2.491 0.0220092 enoyl CoA hydratase 1, peroxisomal CUL4B 4.710 4.670 3.875 2.559 3.591 3.205 −2.490 0.0295602 cullin 4B CYBA 6.748 7.527 7.916 6.211 6.551 5.829 −2.490 0.0380437 cytochrome b-245, alpha polypeptide MAPK7 6.424 6.563 6.632 5.248 5.421 4.334 −2.489 0.0115004 mitogen-activated protein kinase 7 ARHGEF5 8.593 8.717 9.838 7.282 7.482 8.301 −2.482 0.0398296 Rho guanine nucleotide exchange factor (GEF) 5 PSMA6 8.072 9.248 7.884 6.572 6.866 6.873 −2.482 0.0155756 proteasome (prosome, macropain) subunit, alpha type, 6 JOSD1 8.536 8.146 8.624 6.836 6.848 7.315 −2.480 0.0059877 Josephin domain containing 1 C20orf54 3.496 4.914 4.513 2.559 3.204 3.205 −2.478 0.0388120 chromosome 20 open reading frame 54 SCYL1 10.074 9.956 11.773 8.765 9.352 8.764 −2.477 0.0339547 SCY1-like1 (S. cerevisiae) AUH 4.028 3.711 3.754 2.848 2.402 2.404 −2.477 0.0072026 AU RNA binding protein/enoyl-CoA hydratase UPF3A 6.071 6.524 5.508 5.226 5.069 4.050 −2.459 0.0454927 UPF3 regulator of nonsense transcripts homolog A (yeast) SENP3 4.964 5.732 6.140 4.402 4.436 4.716 −2.456 0.0415695 SUMO1 /sentrin/SMT3 specific peptidase 3 SAFE 5.346 6.105 5.178 4.050 3.914 4.367 −2.456 0.0127598 scaffold attachment factor B MYBBP1A 6.075 7.773 6.967 4.992 5.675 5.722 −2.449 0.0362164 MYB binding protein (P160) 1a FAM102A 10.571 11.703 10.134 9.475 8.908 9.280 −2.446 0.0228496 family with sequence similarity 102, member A LRP5 5.601 5.952 5.534 4.009 4.662 4.538 −2.445 0.0111320 low density lipoprotein receptor-related protein 5 TMEM9 5.167 5.157 3.984 3.880 3.519 2.782 −2.440 0.0391097 transmembrane protein 9 MAP1B 8.121 9.302 8.369 7.654 7.659 6.836 −2.437 0.0461005 microtubule-associated protein 1B EPB41L5 3.412 4.873 4.258 2.974 2.974 2.974 −2.435 0.0413292 erythrocyte membrane protein band 4.1 like 5 CENPT 9.137 9.940 10.105 8.658 8.644 8.716 −2.431 0.0342540 centromere protein T SMAD3 9.248 10.481 10.007 8.193 8.726 8.736 −2.429 0.0245012 SMAD family member 3 FLJ23867 5.697 6.270 5.774 4.991 4.607 4.396 −2.426 0.0136884 No description ARSJ 4.763 5.469 5.711 3.692 4.191 4.322 −2.424 0.0243477 arylsulfatase family, member J THOC4 3.954 3.927 3.838 2.649 3.290 2.457 −2.424 0.0213753 THO complex 4 PICK1 7.718 7.667 8.669 6.390 6.640 6.899 −2.423 0.0187245 protein interacting with PRKCA 1 MLST8 4.821 5.572 6.014 4.570 4.276 4.298 −2.419 0.0427183 MTOR associated protein, LST8 homolog (S. cerevisiae) ZNF703 6.128 5.809 6.760 5.486 5.175 3.859 −2.418 0.0485065 zinc finger protein 703 HSD17B3 2.247 2.247 2.878 0.974 0.974 0.974 −2.416 0.0049471 hydroxysteroid (17-beta) dehydrogenases MOSC1 2.247 2.072 2.878 0.974 0.974 0.974 −2.416 0.0082840 MOCO sulphurase C-terminal domain containing 1 C14orf93 2.247 1.692 2.377 0.974 0.974 0.974 −2.416 0.0146416 chromosome 14 open reading frame 93 CMPK2 3.470 4.513 4.133 2.826 3.240 2.650 −2.416 0.0357659 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial C18orf26 3.671 4.246 3.440 2.933 2.402 2.348 −2.410 0.0206646 chromosome 18 open reading frame 26 TCEB2 7.255 7.721 8.397 6.557 6.188 6.453 −2.408 0.0171596 transcription elongation factor B (Sill), polypeptide 2 (18 kDa, elongin B) OSGEP 3.793 4.454 4.202 3.187 1.559 2.970 −2.408 0.0287736 O-sialoglycoprotein endopeptidase DOPEY2 7.426 8.448 6.813 5.777 6.231 6.159 −2.408 0.0273507 dopey family member 2 SIGIRR 6.707 8.282 7.555 6.246 6.290 6.353 −2.404 0.0465733 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain CSNK1G2 6.022 6.452 6.196 4.883 4.760 5.531 −2.399 0.0199378 casein kinase 1, gamma 2 VSIG2 4.282 6.519 5.020 3.772 3.758 3.304 −2.398 0.0395549 V-set and immunoglobulin domain containing 2 MPPED2 3.954 3.263 2.860 1.974 2.692 1.974 −2.398 0.0437429 metallophosphoesterase domain containing 2 SLC25A14 3.593 3.236 2.860 1.974 1.974 1.974 −2.397 0.0101688 solute carrier family 25 (mitochondrial carrier, brain), member 14 SPEN 8.647 8.940 8.595 7.069 7.386 8.095 −2.396 0.0238012 spen homolog, transcriptional regulator (Drosophila) RBM14 5.599 6.718 6.787 4.960 4.893 5.527 −2.394 0.0395695 RNA binding motif protein 14 TSC22D4 6.547 7.618 7.184 6.359 5.177 5.971 −2.394 0.0413484 TSC22 domain family, member 4 MAP2K2 9.747 10.354 10.123 8.864 9.157 8.470 −2.393 0.0153553 mitogen-activated protein kinase kinase 2 FAM63B 4.931 5.419 5.463 4.402 3.711 3.672 −2.393 0.0139478 family with sequence similarity 63, member B FBXO34 4.607 5.059 4.638 3.598 3.598 3.351 −2.388 0.0071274 F-box protein 34 TMEM66 7.487 6.233 5.676 4.421 5.064 5.346 −2.387 0.0405833 transmembrane protein 66 AIMP1 7.081 7.555 6.963 5.364 6.015 6.301 −2.386 0.0193822 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 ANKRD30A 3.814 5.929 3.788 2.559 2.559 2.559 −2.386 0.0258619 ankyrin repeat domain 30A CASP6 4.125 4.588 4.296 3.334 3.334 2.457 −2.384 0.0189923 caspase 6, apoptosis-related cysteine peptidase EHBP1L1 5.944 6.905 6.793 5.655 5.279 5.157 −2.378 0.0284328 EH domain binding protein 1−like 1 DDR1 10.892 12.182 10.870 9.620 9.748 10.104 −2.378 0.0234942 discoidin domain receptor tyrosine kinase 1 DVL1 6.559 5.928 6.802 4.760 5.171 5.553 −2.378 0.0233500 dishevelled, dsh homolog 1 (Drosophila) FXYD3 11.426 11.190 11.624 10.375 10.056 10.160 −2.377 0.0072510 FXYD domain containing ion transport regulator 3 HDAC11 4.687 4.859 4.452 4.026 3.204 3.205 −2.376 0.0221903 histone deacetylase 11 PPIA 8.404 7.762 7.490 6.855 6.398 6.514 −2.374 0.0168281 peptidylproly isomerase A (cyclophilin A) FAH 4.290 5.290 3.820 3.043 2.896 3.043 −2.373 0.0222011 fumarylacetoacetate hydrolase (fumarylacetoacetase) BTBD1 5.035 6.053 5.238 4.190 4.629 3.789 −2.371 0.0330445 BTB (POZ) domain containing 1 RASSF3 2.747 4.038 3.220 1.974 1.974 1.974 −2.371 0.0215480 Ras association (RalGDS/AF-6) domain family member 3 SCPEP1 3.220 3.618 2.673 2.246 1.974 1.974 −2.371 0.0267636 serine carboxypeptidase 1 GPLD1 3.220 4.164 2.905 2.649 1.974 1.974 −2.371 0.0418473 glycosylphosphatidylinositol specific phospholipase D1 SPAG16 6.644 5.947 6.074 5.127 4.997 4.705 −2.366 0.0125157 sperm associated antigen 16 PSMD2 8.407 9.623 9.243 8.113 8.001 7.792 −2.365 0.0406516 proteasome (prosome, macropain) 26S subunit, non- ATPase, 2 STK32C 5.206 6.097 6.796 4.486 4.866 4.856 −2.364 0.0415464 serine/threonine kinase 32C NDUFV2 7.599 9.346 7.297 6.359 6.339 6.437 −2.361 0.0323538 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24 kDa XPOT 6.278 6.854 6.319 5.443 5.615 4.859 −2.361 0.0223377 exportin, tRNA (nuclear export receptor for tRNAs) MPHOSPH8 6.559 7.454 7.588 6.241 5.805 6.215 −2.360 0.0380330 M-phase phosphoprotein 8 COQ4 8.170 8.854 8.934 7.138 7.696 7.607 −2.359 0.0231343 coenzyme Q4 homolog (S. cerevisiae) WAPAL 5.291 6.298 5.749 3.886 4.512 5.136 −2.358 0.0422686 wings apart-like homolog (Drosophila) AKAP8L 7.745 8.796 8.579 7.232 7.560 7.269 −2.356 0.0466163 A kinase (PRKA) anchor protein 8-like LMX1B 5.390 6.272 6.011 4.931 5.037 4.148 −2.355 0.0363515 LIM homeobox transcription factor 1, beta CDK17 4.719 4.843 4.664 3.484 3.337 4.351 −2.354 0.0429586 cyclin-dependent kinase 17 DTWD1 3.220 3.692 2.819 1.974 1.974 2.457 −2.353 0.0285441 DTW domain containing 1 GAK 9.884 10.314 10.592 8.700 9.358 9.077 −2.351 0.0182049 cyclin G associated kinase DECR1 6.508 6.860 6.032 5.627 5.296 4.630 −2.350 0.0268012 2,4-dienoyl CoA reductase 1, mitochondrial BLOC1S3 4.597 5.059 4.450 3.583 3.712 3.220 −2.346 0.0143952 biogenesis of lysosomal organelles complex-1, subunit 3 TP53 5.217 6.596 5.227 3.989 4.334 4.403 −2.342 0.0291051 tumor protein p53 COX4NB 6.973 7.383 7.478 6.046 6.217 6.156 −2.340 0.0098381 COX4 neighbor CD3EAP 5.696 6.551 6.855 4.729 5.411 5.325 −2.338 0.0379816 CD3e molecule, epsilon associated protein F11R 8.340 8.240 7.301 7.117 6.288 6.967 −2.334 0.0446569 F11 receptor RRAGC 8.238 7.965 7.857 6.742 6.407 7.016 −2.334 0.0088757 Ras-related GTP binding C LYPLAL1 3.220 3.196 2.347 1.974 1.974 1.974 −2.332 0.0452034 lysophospholipase-like 1 MAP2K4 5.454 5.334 5.091 3.872 4.144 4.230 −2.328 0.0070407 mitogen-activated protein kinase kinase 4 CYTSA 7.323 8.109 7.978 6.697 6.890 6.355 −2.327 0.0230276 No description LATS2 7.418 7.512 6.490 5.271 5.958 6.469 −2.326 0.0479048 LATS, large tumor suppressor, homolog 2 (Drosophila) NR3C2 4.554 4.882 4.042 3.271 3.337 3.605 −2.324 0.0243991 nuclear receptor subfamily 3, group C, member 2 CEBPG 6.168 6.652 5.929 4.791 5.048 4.952 −2.323 0.0093638 CCAAT/enhancer binding protein (C/EBP), gamma HDAC2 6.617 6.264 6.523 4.879 5.308 5.519 −2.322 0.0112149 histone deacetylase 2 RDH13 6.043 5.378 5.687 3.992 4.651 4.828 −2.321 0.0232870 retinol dehydrogenase 13 (all-trans/9-cis) PLAT 6.802 8.373 7.601 6.550 6.388 5.667 −2.318 0.0409831 plasminogen activator, tissue C11orf60 4.126 4.255 3.222 3.043 2.559 2.559 −2.317 0.0364935 No description RAD54L2 5.765 6.940 6.246 5.038 5.044 4.925 −2.310 0.0202341 RAD54-like 2 (S. cerevisiae) MED22 5.291 6.089 6.055 4.121 4.881 4.520 −2.310 0.0205756 mediator complex subunit 22 ZBTB8A 10.008 9.432 9.509 7.928 8.303 8.903 −2.306 0.0218135 zinc finger and BTB domain containing 8A PDRG1 5.410 5.624 5.556 3.583 4.353 4.806 −2.302 0.0245518 p53 and DNA-damage regulated 1 C12orf45 6.630 5.874 6.696 3.855 5.494 5.447 −2.300 0.0454582 chromosome 12 open reading frame 45 EID1 6.602 6.100 5.882 4.795 4.927 4.899 −2.299 0.0088051 EP300 interacting inhibitor of differentiation 1 PRKCD 7.948 7.425 7.446 5.013 6.247 7.008 −2.296 0.0417183 protein kinase C, delta RBM42 6.241 6.286 5.924 3.913 5.567 5.042 −2.296 0.0447429 RNA binding motif protein 42 ALDH5A1 4.205 4.463 3.979 2.943 2.782 3.351 −2.293 0.0131481 aldehyde dehydrogenase 5 family, member A1 KRTAP1-1 1.913 1.688 1.169 0.845 −0.026 −0.026 −2.288 0.0220990 keratin associated protein 1-1 ARRB2 5.244 5.676 6.414 4.550 4.431 4.482 −2.288 0.0215917 arrestin, beta 2 ZNHIT2 4.662 4.952 4.649 3.772 0.974 3.469 −2.286 0.0411435 zinc finger, HIT-type containing 2 SLU7 6.704 7.339 6.671 5.479 5.877 5.630 −2.285 0.0136101 SLU7 splicing factor homolog (S. cerevisiae) E2F1 3.470 3.613 3.841 1.911 2.648 2.650 −2.284 0.0158112 E2F transcription factor 1 TSC2 6.930 7.776 7.574 6.398 6.383 6.284 −2.283 0.0245411 tuberous sclerosis 2 ORMDL2 6.148 7.132 7.262 5.145 6.072 5.214 −2.282 0.0323431 ORM1-like 2 (S. cerevisiae) EEF2 14.955 16.172 15.875 14.191 14.685 14.777 −2.281 0.0498012 eukaryotic translation elongation factor 2 FGF13 4.192 3.436 3.786 2.246 3.196 2.457 −2.281 0.0336769 fibroblast growth factor 13 ATP6VOE2 6.128 6.568 6.692 5.950 4.623 5.379 −2.279 0.0485173 ATPase, H+ transporting VO subunit e2 AR 3.706 4.854 3.468 2.518 2.296 2.695 −2.278 0.0211719 androgen receptor DHX29 4.473 4.672 4.091 3.246 2.974 3.484 −2.278 0.0142341 DEAH (Asp-Glu-Ala-His) box polypeptide 29 C1orf126 5.489 5.912 4.969 4.534 4.279 4.302 −2.277 0.0280384 chromosome 1 open reading frame 126 CFL1 12.836 13.123 12.737 11.649 12.373 11.452 −2.277 0.0326408 cofilin 1 (non-muscle) SVOPL 2.878 2.108 2.404 0.974 1.692 0.974 −2.276 0.0221305 SVOP-like PLD2 5.972 6.416 6.555 5.157 4.787 5.459 −2.273 0.0180399 phospholipase D2 FAM174A 6.630 7.017 7.809 6.324 6.023 5.447 −2.270 0.0414213 family with sequence similarity 174, member A NKRF 4.678 4.944 4.196 3.802 2.840 3.496 −2.269 0.0281213 NFKB repressing factor HMG20B 8.123 8.161 7.901 6.942 6.491 7.373 −2.266 0.0219985 high-mobility group 20B PEX1 4.664 5.323 4.793 3.809 3.934 3.484 −2.266 0.0155863 peroxisomal biogenesis factor 1 SLC17A5 4.664 5.739 4.305 3.462 3.638 3.484 −2.266 0.0279808 solute carrier family 17 (anion/sugar transporter), member 5 PPEF2 3.966 3.288 3.826 2.108 2.636 3.152 −2.265 0.0475088 protein phosphatase, EF-hand calcium binding domain 2 RPL17 14.350 15.321 14.899 13.721 13.721 13.978 −2.262 0.0333484 ribosomal protein L17 EBPL 3.953 2.869 2.878 1.845 1.692 1.819 −2.261 0.0159325 emopamil binding protein-like ROBOS 6.773 7.015 7.611 5.600 6.106 6.437 −2.256 0.0402809 roundabout, axon guidance receptor, homolog 3 (Drosophila) FANK1 3.597 4.283 4.033 2.860 3.196 1.974 −2.255 0.0315979 fibronectin type III and ankyrin repeat domains 1 ZER1 8.113 8.619 9.010 7.447 7.595 7.110 −2.253 0.0213070 zer-1 homolog (C. elegans) CHD2 11.739 11.416 11.378 9.707 10.247 10.975 −2.248 0.0349870 chromodomain helicase DNA binding protein 2 ZSWIM4 5.930 6.149 5.368 4.404 4.612 4.980 −2.248 0.0231059 zinc finger, SWIM-type containing 4 ARHGAP30 6.223 5.928 5.532 4.416 5.055 4.684 −2.246 0.0196999 Rho GTPase activating protein 30 SLC38A10 5.846 6.796 6.167 5.511 5.001 4.851 −2.244 0.0325641 solute carrier family 38, member 10 ENO1 10.548 11.155 10.574 9.854 9.957 9.385 −2.240 0.0300522 enolase 1, (alpha) TCTN3 5.222 6.195 5.661 4.183 5.182 4.059 −2.239 0.0460115 tectonic family members NCBP2 4.631 5.837 4.956 3.469 3.831 4.445 −2.238 0.0462648 nuclear cap binding protein subunit 2, 20 kDa SND1 9.312 9.888 9.900 8.530 8.737 8.619 −2.238 0.0168557 staphylococcal nuclease and tudor domain containing 1 SMG1 7.506 7.127 6.360 5.604 5.495 6.344 −2.237 0.0455035 SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) IPO5 8.368 7.632 7.318 6.373 6.471 6.837 −2.236 0.0265948 importin 5 ADIPOR1 7.922 8.223 7.462 6.302 6.871 6.783 −2.235 0.0185518 adiponectin receptor 1 MCL1 11.032 10.699 10.271 9.111 9.379 10.099 −2.235 0.0383768 myeloid cell leukemia sequence 1 (BCL2-related) SH3GLB2 9.492 10.108 9.986 8.848 8.480 8.827 −2.232 0.0154198 SH3-domain GRB2-like endophilin B2 C11orf66 3.954 4.492 5.386 3.334 3.334 2.860 −2.231 0.0256040 chromosome 11 open reading frame 66 DHRS13 6.389 5.167 5.380 4.222 4.448 4.098 −2.231 0.0215050 dehydrogenase/reductase (SDR family) member 13 TINF2 3.709 4.575 3.674 2.518 2.627 2.695 −2.229 0.0134574 TERF1 (TRF1−interacting nuclear factor 2 TNIP2 4.360 5.296 4.462 4.050 3.204 3.496 −2.229 0.0438665 TNFAIP3 interacting protein 2 TTLL3 7.969 7.784 7.979 5.945 6.823 6.815 −2.228 0.0130307 tubulin tyrosine ligase-like family, member 3 RIF1 5.396 6.295 5.221 4.066 4.537 4.302 −2.228 0.0209877 RAP1 interacting factor homolog (yeast) SNRNP200 7.973 7.618 7.604 6.216 6.463 7.010 −2.227 0.0190200 small nuclear ribonucleoprotein 200 kDa (U5) ING3 4.363 5.237 5.640 4.102 3.234 4.083 −2.225 0.0435073 inhibitor of growth family, member 3 ATP5D 9.246 10.106 10.075 8.988 8.846 8.092 −2.225 0.0404712 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit ATP1A1 10.473 11.507 10.011 9.321 8.952 9.783 −2.222 0.0448511 ATPase, Na+/K+ transporting, alpha 1 polypeptide GMPPA 6.610 5.957 7.468 5.727 5.556 4.806 −2.220 0.0477521 GDP-mannose pyrophosphorylase A ACTN4 11.569 12.037 11.960 10.493 10.890 10.419 −2.219 0.0096616 actinin, alpha 4 RBMX 3.059 2.037 3.032 1.911 1.559 1.559 −2.216 0.0493822 RNA binding motif protein, X-linked SNRPB 11.046 12.159 11.143 9.898 10.032 10.426 −2.215 0.0250837 small nuclear ribonucleoprotein polypeptides B and B1 VPS41 5.817 4.819 5.323 3.949 3.900 4.670 −2.215 0.0397107 vacuolar protein sorting 41 homolog (S. cerevisiae) IRS1 5.418 5.276 5.408 4.271 4.244 4.144 −2.215 0.0031005 insulin receptor substrate 1 ZNF124 3.059 2.948 2.703 1.559 2.075 1.559 −2.209 0.0122180 zinc finger protein 124 FAF2 5.185 5.414 4.459 4.271 4.004 3.629 −2.208 0.0435541 Fas associated factor family member 2 UQCRH 11.100 11.143 10.638 9.790 9.634 10.000 −2.207 0.0121965 ubiquinol-cytochrome c reductase hinge protein PYGB 9.135 9.129 8.535 7.881 7.929 7.992 −2.207 0.0213323 phosphorylase, glycogen; brain NAA25 8.010 7.421 7.505 6.282 6.655 6.781 −2.202 0.0213484 N(alpha)-acetyltransferase 25, NatB auxiliary subunit PCBP1 8.278 7.400 6.702 5.876 6.274 6.262 −2.199 0.0385602 poly(rC) binding protein 1 RASL10A 6.177 4.810 6.118 3.809 3.817 5.041 −2.198 0.0453392 RAS-like, family 10, member A ZNF625 4.851 5.416 5.070 3.767 4.282 3.859 −2.195 0.0160123 zinc finger protein 625 MIDN 10.614 10.965 10.756 9.623 9.321 10.073 −2.194 0.0197421 midnolin OR2H1 2.878 2.108 1.692 0.974 0.974 0.974 −2.193 0.0246654 olfactory receptor, family 2, subfamily H, member 1 LRRC29 2.247 1.505 2.108 0.974 0.974 0.974 −2.193 0.0276577 leucine rich repeat containing 29 DUSP15 2.247 2.878 2.108 0.974 0.974 1.819 −2.193 0.0366086 dual specificity phosphatase 15 HBXIP 8.837 8.856 8.115 6.983 7.755 7.649 −2.193 0.0334658 hepatitis B virus x interacting protein PXN 6.730 6.252 6.159 5.015 5.378 5.601 −2.189 0.0244206 paxillin PSMD8 8.274 9.281 8.620 7.543 7.364 7.492 −2.187 0.0182893 proteasome (prosome, macropain) 26S subunit, non- ATPase, 8 FLJ36031 3.814 4.332 3.746 2.559 2.840 3.205 −2.183 0.0235741 No description ABCC8 3.908 3.979 4.919 3.205 3.026 2.782 −2.183 0.0237744 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 VLDLR 3.706 4.594 4.303 3.179 3.469 2.296 −2.181 0.0428826 very low density lipoprotein receptor NOB1 4.741 4.953 5.408 3.943 4.062 3.616 −2.180 0.0162333 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) LRRC8A 9.392 9.528 9.904 8.407 8.030 8.894 −2.175 0.0229701 leucine rich repeat containing 8 family, member A SLC39A6 6.383 7.667 6.534 5.391 5.415 5.887 −2.171 0.0347913 solute carrier family 39 (zinc transporter), member 6 QRICH1 5.536 4.497 4.157 3.144 3.939 3.379 −2.170 0.0478573 glutamine-rich 1 TOLLIP 7.322 8.270 7.887 6.484 6.911 6.772 −2.166 0.0295288 toll interacting protein URM1 4.687 5.386 4.915 3.837 3.802 3.787 −2.164 0.0119693 ubiquitin related modifier 1 FTO 6.178 5.649 5.498 5.065 4.516 4.489 −2.163 0.0269348 fat mass and obesity associated THAP9 3.059 3.187 2.602 1.911 2.075 1.559 −2.161 0.0191566 THAP domain containing 9 NQO1 5.435 5.943 5.382 4.577 4.836 4.165 −2.154 0.0266577 NAD(P)H dehydrogenase, quinone 1 CTSB 10.678 11.251 10.884 9.788 9.882 9.572 −2.152 0.0105649 cathepsin B ATM 5.090 5.219 4.842 3.992 3.638 4.115 −2.149 0.0115879 ataxia telangiectasia mutated HSD11B1L 5.410 5.201 5.753 4.457 4.098 4.378 −2.148 0.0126654 hydroxysteroid (11-beta) dehydrogenase 1−like GGT5 4.770 5.325 5.748 4.527 4.222 3.704 −2.147 0.0398020 gamma-glutamyltransferase 5 PSME1 9.531 9.260 8.584 8.159 8.161 8.241 −2.142 0.0453607 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) KCNMA1 6.408 6.950 6.912 5.814 5.968 5.013 −2.140 0.0318181 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 RPL26L1 5.514 5.850 5.584 3.966 5.041 4.486 −2.140 0.0294712 ribosomal protein L26-like 1 KIAA0247 8.582 8.962 8.190 7.484 7.481 7.865 −2.139 0.0350898 KIAA0247 MIF 11.283 11.750 11.921 10.772 10.653 10.300 −2.138 0.0211827 macrophage migration inhibitory factor (glycosylation- inhibiting factor) VCP 8.109 8.753 9.094 7.884 7.657 7.249 −2.138 0.0432517 valosin-containing protein RARA 9.385 8.564 9.421 7.468 7.967 8.330 −2.138 0.0331320 retinoic acid receptor, alpha TESK2 4.991 3.655 3.523 2.746 2.559 2.559 −2.136 0.0290361 testis-specific kinase 2 CLIP1 7.184 6.979 6.201 5.459 5.898 5.886 −2.134 0.0426416 CAP-GLY domain containing linker protein 1 CDT1 3.389 3.043 3.524 2.296 2.296 2.296 −2.133 0.0125756 chromatin licensing and DNA replication factor 1 TMEM38A 2.519 3.032 2.650 1.559 1.559 1.559 −2.129 0.0083530 transmembrane protein 38A ZDHHC8P 2.519 2.650 3.032 1.559 1.559 1.559 −2.129 0.0083530 No description TTC18 3.059 3.059 2.650 1.559 2.075 1.559 −2.129 0.0130952 tetratricopeptide repeat domain 18 ZNF506 3.059 2.650 2.802 1.559 2.075 1.559 −2.129 0.0157575 zinc finger protein 506 DALRD3 7.792 8.755 7.553 6.704 6.524 6.855 −2.127 0.0230829 DALR anticodon binding domain containing 3 GLIPR1 9.871 9.773 10.020 7.964 8.782 9.002 −2.126 0.0185349 GLI pathogenesis-related 1 WDR13 8.029 8.218 8.639 6.989 7.132 7.352 −2.123 0.0142809 WD repeat domain 13 PRAGMIN 5.772 6.827 5.877 5.082 4.687 4.954 −2.121 0.0258028 No description INTS1 8.956 8.769 9.699 7.686 8.486 7.878 −2.118 0.0406132 integrator complex subunit 1 BMP7 8.048 7.381 8.232 7.054 6.588 6.967 −2.116 0.0374359 bone morphogenetic protein 7 RABI 5 6.625 7.025 7.051 5.544 5.653 6.034 −2.115 0.0129233 RAB15, member RAS onocogene family CPEB1 2.671 3.188 4.208 2.108 2.105 2.108 −2.115 0.0419325 cytoplasmic polyadenylation element binding protein 1 CCDC142 4.870 3.824 3.507 2.746 2.559 2.899 −2.110 0.0297383 coiled-coil domain containing 142 CHRNB1 4.481 4.951 4.886 3.936 2.896 3.809 −2.109 0.0282962 cholinergic receptor, nicotinic, beta 1 (muscle) UBA1 9.070 8.731 9.508 7.996 7.869 8.312 −2.106 0.0275633 ubiquitin-like modifier activating enzyme 1 DYNC1LI2 9.782 10.109 9.411 8.906 8.524 8.711 −2.101 0.0216025 dynein, cytoplasmic 1, light intermediate chain 2 CA13 6.138 6.163 5.996 4.866 5.068 5.558 −2.100 0.0290760 carbonic anhydrase XIII C10orf57 3.364 3.468 3.043 2.296 2.296 2.296 −2.097 0.0120038 chromosome 10 open reading frame 57 HOOK2 5.403 5.233 5.631 4.152 4.342 4.735 −2.087 0.0211051 hook homolog 2 (Drosophila) LRSAM1 6.962 6.052 6.670 5.611 5.645 5.571 −2.084 0.0397644 leucine rich repeat and sterile alpha motif containing 1 CCDC85C 7.319 7.574 7.259 4.837 6.306 6.515 −2.083 0.0332686 coiled-coil domain containing 85C MRPL55 8.397 8.148 9.120 7.220 7.753 7.339 −2.082 0.0339939 mitochondrial ribosomal protein L55 PGAP2 5.659 4.686 4.555 3.821 3.594 3.629 −2.080 0.0233776 post-GPI attachment to proteins 2 VAPA 7.879 7.723 7.000 6.049 5.944 6.968 −2.080 0.0405280 VAMP (vesicle-associated membrane protein)-associated protein A, 33 kDa ARL6IP4 7.447 8.245 7.471 6.712 6.392 6.454 −2.078 0.0190975 ADP-ribosylation-like factor 6 interacting protein 4 TFE3 6.422 6.456 6.788 5.367 5.648 5.713 −2.077 0.0163093 transcription factor binding to IGHM enhancer 3 NHS 4.548 4.492 4.564 3.043 3.632 3.496 −2.073 0.0111213 Nance-Horan syndrome (congenital cataracts and dental anomalies) FAM192A 4.811 4.533 4.167 3.246 3.483 3.672 −2.071 0.0219371 family with sequence similarity 192, member A TULP3 6.637 6.948 6.540 5.061 5.902 5.852 −2.064 0.0289317 tubby like protein 3 PEX14 5.178 5.388 4.944 3.900 4.444 3.944 −2.062 0.0184658 peroxisomal biogenesis factor 14 LRRC37B 4.215 4.627 5.214 3.446 3.583 3.704 −2.062 0.0285986 leucine rich repeat containing 37B LGALS8 6.581 6.274 6.530 5.414 5.537 5.251 −2.061 0.0092686 lectin, galactoside-binding, soluble, 8 GAS2L1 5.799 6.180 5.909 4.866 4.347 5.460 −2.061 0.0404436 growth arrest-specific 2 like 1 RELA 9.484 9.155 8.633 8.076 7.943 8.443 −2.057 0.0472433 v-rel reticuloendotheliosis viral oncogene homolog A (avian) ZNF117 4.428 4.269 3.820 3.462 3.026 2.782 −2.054 0.0256922 zinc finger protein 117 C21orf49 6.387 6.175 6.406 5.351 5.462 4.857 −2.051 0.0150806 chromosome 21 open reading frame 49 ITPR2 7.138 7.705 7.379 6.961 6.103 6.168 −2.050 0.0460491 inositol 1,4,5-triphosphate receptor, type 2 WDFY2 6.065 5.693 6.105 4.933 5.070 5.010 −2.049 0.0152893 WD repeat and FYVE domain containing 2 GTPBP6 7.239 7.117 7.062 6.084 5.891 6.327 −2.046 0.0110929 GTP binding protein 6 (putative) MRPS24 9.495 10.190 9.758 8.727 8.725 9.103 −2.044 0.0316170 mitochondrial ribosomal protein S24 KIAA0240 4.893 5.093 4.705 4.234 3.811 3.675 −2.041 0.0221412 KIAA0240 PGR 3.831 4.559 4.408 3.484 3.144 3.379 −2.040 0.0368342 progesterone receptor TFEB 3.954 4.529 4.362 3.013 3.334 3.404 −2.038 0.0201742 transcription factor EB SUDS3 5.262 6.036 4.895 4.347 4.243 3.991 −2.027 0.0290253 suppressor of defective silencing 3 homolog (S. cerevisiae) RNF149 7.698 7.193 6.995 5.988 6.175 6.427 −2.026 0.0207966 ring finger protein 149 CCDC9 6.133 5.794 6.613 4.776 5.381 5.263 −2.025 0.0361243 coiled-coil domain containing 9 IER2 12.147 12.120 12.727 11.299 11.106 11.580 −2.020 0.0278196 immediate early response 2 LRRK1 5.214 5.486 5.361 3.782 4.350 4.490 −2.014 0.0160867 leucine-rich repeat kinase 1 DHPS 5.575 5.649 5.564 3.685 4.565 4.904 −2.014 0.0304198 deoxyhypusine synthase FYTTD1 5.316 5.135 4.582 4.126 4.264 4.060 −2.013 0.0430015 forty-two-three domain containing 1 TAF5L 5.145 5.781 4.858 4.362 3.849 4.419 −2.012 0.0400054 TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65 kDa FAM116B 6.107 6.446 7.425 5.443 5.704 5.288 −2.005 0.0423262 family with sequence similarity 116, member B ENTPD4 3.709 4.327 3.299 2.709 2.896 2.296 −2.004 0.0337667 ectonucleoside triphosphate diphosphohydrolase 4 MAP1LC3B 9.117 8.080 8.085 7.479 7.090 7.081 −1.999 0.0311757 microtubule-associated protein 1 light chain 3 beta CDK4 4.360 4.862 4.413 2.911 3.772 3.869 −1.991 0.0469378 cyclin-dependent kinase 4 ADPRHL2 4.486 5.798 4.739 3.532 4.186 3.747 −1.989 0.0484321 ADP-ribosylhydrolase like 2 RUSC2 5.304 5.059 5.470 4.004 4.551 4.316 −1.983 0.0217176 RUN and SH3 domain containing 2 KCTD5 2.519 3.439 2.544 2.194 1.559 1.559 −1.979 0.0480714 potassium channel tetramerisation domain containing 5 TMX1 4.931 6.199 4.828 4.064 3.844 4.085 −1.978 0.0343860 thioredoxin-related transmembrane protein 1 C11orf31 8.280 8.133 8.086 7.243 7.300 7.040 −1.973 0.0097675 chromosome 11 open reading frame 31 OBFC1 6.526 7.511 6.392 5.786 5.937 5.416 −1.966 0.0469785 oligonucleotide/oligosaccharide-binding fold containing 1 MLH3 4.948 5.411 5.168 3.994 4.193 4.228 −1.966 0.0127982 mutL homolog 3 (E. coli) NKIRAS2 6.339 7.219 6.120 5.708 5.148 5.365 −1.965 0.0377145 NFKB inhibitor interacting Ras-like 2 ALOXE3 5.896 6.602 6.369 4.936 4.922 5.689 −1.964 0.0340583 arachidonate lipoxygenase 3 UBE2R2 11.165 10.788 10.753 9.781 9.908 10.164 −1.961 0.0206285 ubiquitin-conjugating enzyme E2R 2 GALNT3 6.079 5.576 5.200 4.607 4.412 4.759 −1.958 0.0320422 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N- acetylgalactosaminyltransferase 3 (GalNAc-T3) PSMD7 7.079 7.830 6.771 6.111 6.343 6.064 −1.956 0.0393914 proteasome (prosome, macropain) 26S subunit, non- ATPase, 7 WDR6 6.914 7.031 6.852 5.225 5.947 6.469 −1.954 0.0486731 WD repeat domain 6 FAM108C1 4.870 5.901 4.996 4.315 4.347 3.907 −1.949 0.0441827 family with sequence similarity 108, member C1 CYP2J2 2.519 2.650 2.404 1.559 1.559 1.559 −1.944 0.0077874 cytochrome P450, family 2, subfamily J, polypeptide 2 C1orf152 2.519 2.404 3.459 1.559 1.559 1.559 −1.944 0.0239386 chromosome 1 open reading frame 152 LOC643763 3.519 4.033 3.324 2.746 2.559 2.559 −1.944 0.0240054 No description CD1D 2.519 2.602 2.037 1.559 1.559 1.559 −1.944 0.0344114 CD1d molecule ZC3HC1 2.519 3.059 2.075 1.559 1.559 1.559 −1.944 0.0382030 zinc finger, C3HC-type containing 1 TTC33 2.519 3.059 2.037 1.559 1.559 1.559 −1.944 0.0423983 tetratricopeptide repeat domain 33 RAD51L3 3.814 3.574 3.516 2.559 2.559 3.205 −1.941 0.0446462 RAD51-like 3 (S. cerevisiae) SEC14L2 7.988 8.479 8.232 7.554 7.276 5.957 −1.941 0.0473461 SEC14-like 2 (S. cerevisiae) PFKFB3 8.608 7.714 7.345 6.763 6.551 6.772 −1.933 0.0351543 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 CHMP4B 8.885 8.887 8.641 7.387 7.934 8.216 −1.933 0.0362855 chromatin modifying protein 4B TMEM30A 8.214 9.244 8.557 7.608 7.567 7.876 −1.930 0.0466500 transmembrane protein 30A KIAA0831 6.716 6.614 5.943 5.380 5.285 5.770 −1.926 0.0445464 No description PEBP1 10.120 11.108 10.106 9.212 9.562 9.161 −1.925 0.0364827 phosphatidylethanolamine binding protein 1 B3GALNT2 5.539 6.990 5.984 4.957 5.039 5.040 −1.925 0.0487276 beta-1,3-N-acetylgalactosaminyltransferase 2 TRMU 6.420 6.687 7.009 6.064 5.341 5.823 −1.924 0.0390737 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase UFC1 10.570 10.094 10.572 9.566 9.494 9.629 −1.922 0.0283776 ubiquitin-fold modifier conjugating enzyme 1 TACC2 6.664 5.383 5.510 4.713 4.877 4.444 −1.917 0.0459524 transforming, acidic coiled-coil containing protein 2 TRPM4 4.862 5.363 5.218 4.300 4.272 4.280 −1.916 0.0236685 transient receptor potential cation channel, subfamily M, member 4 RNF126 5.292 5.747 6.308 4.882 4.811 4.407 −1.913 0.0368511 ring finger protein 126 GART 5.437 5.852 6.033 4.501 5.152 4.623 −1.913 0.0316585 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase DAB2IP 6.185 5.998 5.250 4.315 4.539 5.259 −1.913 0.0499117 DAB2 interacting protein SCAMP4 5.680 6.338 5.932 5.042 4.998 4.810 −1.911 0.0194896 secretory carrier membrane protein 4 BBS1 4.428 3.715 3.616 2.782 2.782 3.077 −1.910 0.0305035 Bardet-Biedl syndrome 1 LHPP 5.742 5.371 6.240 4.439 5.012 4.907 −1.909 0.0425188 phospholysine phosphohistidine inorganic pyrophosphate phosphatase GFOD2 7.794 8.034 8.315 7.102 7.092 7.317 −1.908 0.0260591 glucose-fructose oxidoreductase domain containing 2 C19orf60 6.182 6.468 7.284 5.551 5.537 5.335 −1.906 0.0295979 chromosome 19 open reading frame 60 LOC1001308 2.747 2.953 2.905 1.974 1.974 1.974 −1.906 0.0092418 No description 72 MAP2K7 8.660 8.668 8.923 7.805 7.688 7.992 −1.905 0.0151489 mitogen-activated protein kinase kinase 7 IMPDH1 8.028 8.541 9.312 7.317 7.614 7.662 −1.902 0.0478358 IMP (inosine 5′-monophosphate) dehydrogenase 1 RBMXL1 3.810 3.487 3.074 2.559 2.559 2.559 −1.901 0.0339225 RNA binding motif protein, X-linked-like 1 TIMM44 8.296 8.579 8.573 7.352 7.647 7.768 −1.901 0.0219877 translocase of inner mitochondrial membrane 44 homolog (yeast) SFRS9 7.187 8.017 7.102 6.175 6.342 6.447 −1.901 0.0285334 No description ARIH2 7.143 7.651 7.173 6.218 6.557 6.693 −1.899 0.0443415 ariadne homolog 2 (Drosophila) FXN 6.542 6.446 6.674 5.639 5.749 5.319 −1.898 0.0144436 frataxin NAA50 5.999 6.454 6.198 5.135 5.106 5.530 −1.897 0.0224996 N(alpha)-acetyltransferase 50, NatE catalytic subunit C17orf81 4.643 4.789 4.738 3.758 4.196 3.728 −1.887 0.0291888 chromosome 17 open reading frame 81 CDC37 10.638 11.029 10.948 9.617 10.033 10.124 −1.886 0.0247698 cell division cycle 37 homolog (S. cerevisiae) DUSP19 8.162 8.463 8.160 7.252 6.945 7.656 −1.879 0.0280952 dual specificity phosphatase 19 TTC27 5.186 4.920 4.543 3.891 4.276 3.809 −1.879 0.0401642 tetratricopeptide repeat domain 27 GPX4 12.474 12.038 12.785 11.128 11.734 11.635 −1.878 0.0471220 glutathione peroxidase 4 (phospholipid hydroperoxidase) LRRC4 5.274 5.700 5.386 4.366 4.649 4.698 −1.876 0.0249286 leucine rich repeat containing 4 TOM1L2 6.733 6.518 7.212 5.610 6.016 5.951 −1.876 0.0322955 target of myb1-like 2 (chicken) NLRP8 8.646 8.522 8.027 7.623 7.186 7.693 −1.864 0.0420499 NLR family, pyrin domain containing 8 STK38L 5.192 4.836 4.496 3.865 4.197 3.937 −1.864 0.0453500 serine/threonine kinase 38 like PITPNM1 6.123 6.228 6.276 5.102 5.335 5.446 −1.857 0.0140184 phosphatidylinositol transfer protein, membrane-associated 1 ALDH2 7.246 7.093 7.188 6.201 6.462 6.233 −1.856 0.0138196 aldehyde dehydrogenase 2 family (mitochondrial) TRAPPC3 6.087 6.472 6.408 4.882 5.518 5.682 −1.852 0.0390844 trafficking protein particle complex 3 SAPS2 6.764 7.209 7.836 5.926 6.326 6.320 −1.852 0.0388672 No description TIA1 4.505 4.920 4.646 3.656 4.034 3.739 −1.849 0.0256147 TIA1 cytotoxic granule-associated RNA binding protein PRKCI 6.033 6.451 6.330 4.366 5.522 5.565 −1.849 0.0499816 protein kinase C, iota FOXH1 2.747 2.860 3.922 1.974 1.974 1.974 −1.847 0.0330652 forkhead box H1 PDGFB 4.280 4.015 4.121 3.117 3.543 3.236 −1.847 0.0260376 platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) COMMD9 6.844 6.474 6.661 5.806 5.968 5.274 −1.836 0.0294336 COMM domain containing 9 MRPL45 7.565 8.075 7.705 6.832 7.194 6.734 −1.832 0.0371458 mitochondrial ribosomal protein L45 TRAF3 4.687 5.599 4.921 4.050 3.914 4.378 −1.829 0.0488051 TNF receptor-associated factor 3 ANXA4 6.148 7.091 5.986 5.240 5.379 5.285 −1.820 0.0376416 annexin A4 SLC15A4 5.339 5.090 4.615 4.230 4.264 3.899 −1.816 0.0430576 solute carrier family 15, member 4 UQCRC1 9.446 9.771 9.341 8.950 8.590 8.407 −1.811 0.0356500 ubiquinol-cytochrome c reductase core protein l RICS 8.263 7.376 7.197 6.386 6.541 6.522 −1.807 0.0327544 No description SF1 10.054 10.489 10.075 9.033 9.437 9.637 −1.805 0.0466922 splicing factor 1 CDIPT 5.597 5.668 5.121 4.623 4.816 4.619 −1.804 0.0444881 CDP-diacylglycerol inositol 3-phosphatidyltransferase CCDC90A 3.364 3.126 4.166 2.518 2.296 2.695 −1.799 0.0420084 coiled-coil domain containing 90A SLAMF8 4.899 3.704 3.966 3.196 3.196 2.860 −1.796 0.0445196 SLAM family member 8 PLK1 3.220 3.966 3.220 2.649 2.377 2.457 −1.793 0.0354259 polo-like kinase 1 C1QTNF6 4.167 4.344 4.242 3.296 3.471 3.509 −1.783 0.0153768 C1q and tumor necrosis factor related protein 6 RETSAT 7.537 7.329 7.512 6.512 6.705 6.595 −1.780 0.0140591 retinol saturase (all-trans-retinol 13,14-reductase) C14orf101 3.728 3.949 4.094 3.117 2.974 3.236 −1.780 0.0249624 chromosome 14 open reading frame 101 LMLN 4.351 3.970 4.231 3.144 3.337 3.581 −1.772 0.0322049 leishmanolysin-like (metallopeptidase M8 family) C12orf57 10.947 10.712 10.768 9.944 9.873 10.137 −1.770 0.0192924 chromosome 12 open reading frame 57 NDEL1 4.652 4.643 4.777 4.146 3.815 3.831 −1.767 0.0280491 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 CSNK2B 9.848 10.972 10.054 9.254 9.233 9.027 −1.767 0.0374106 casein kinase 2, beta polypeptide FSDIL 2.519 2.375 2.627 1.559 2.075 1.559 −1.760 0.0456654 fibronectin type III and SPRY domain containing 1−like SUCLG1 9.105 8.634 8.550 7.737 7.901 8.107 −1.756 0.0381596 succinate-CoA ligase, alpha subunit RPL41 17.551 16.677 16.677 15.865 15.865 15.865 −1.756 0.0276055 ribosomal protein L41 PPL 5.488 6.396 5.516 4.677 4.907 4.861 −1.754 0.0442203 periplakin CWC25 5.371 4.973 4.665 4.327 3.900 4.163 −1.753 0.0439870 CWC25 spliceosome-associated protein homolog (S. cerevisiae) DNTTIP2 6.810 6.702 6.851 5.983 6.263 5.894 −1.751 0.0315380 deoxynucleotidyltransferase, terminal, interacting protein 2 ATNI 9.576 9.902 10.308 9.152 9.094 9.078 −1.751 0.0453975 atrophin 1 LOC151162 5.052 5.392 4.763 4.243 4.248 4.419 −1.746 0.0488373 No description NUCB1 7.571 7.104 7.266 6.139 6.772 6.471 −1.740 0.0443062 nucleobindin 1 KLF13 7.873 7.671 7.282 6.895 6.879 6.624 −1.732 0.0417690 Kruppel-like factor 13 NTRK3 2.747 2.976 3.091 1.974 1.974 2.457 −1.708 0.0416953 neurotrophic tyrosine kinase, receptor, type 3 KCMF1 7.964 7.201 7.402 6.606 6.645 6.748 −1.690 0.0448350 potassium channel modulatory factor 1 BNIP1 6.322 5.995 5.778 5.370 5.273 5.273 −1.650 0.0469163 BCL2/adenovirus E1B 19 kDa interacting protein 1 OSCP1 5.554 5.478 5.277 4.746 4.844 4.705 −1.636 0.0348695 organic solute carrier partner 1 SLC12A9 3.911 3.769 3.753 3.205 3.026 3.077 −1.632 0.0238173 solute carrier family 12 (potassium/chloride transporters), member 9 FGFBP3 3.220 2.673 2.667 1.974 1.974 1.974 −1.623 0.0291397 fibroblast growth factor binding protein 3 CTBP2 5.396 5.042 4.964 4.266 4.500 4.462 −1.622 0.0440246 C-terminal binding protein 2 TMEM181 8.024 7.992 7.697 7.002 7.308 7.298 −1.620 0.0463438 transmembrane protein 181 PFKFB2 3.944 4.234 3.927 3.296 3.296 3.296 −1.566 0.0265272 6-phosphofructo-2-kinase/fructose-2.6-biphosphatase 2 KIAA0090 3.999 4.102 3.943 3.462 3.377 2.974 −1.559 0.0422479 KIAA0090 Higher Expression in Parous LOC388692 6.190 6.225 6.353 6.958 6.717 6.890 1.521 0.0483277 No description PGBD2 1.559 1.559 1.559 2.404 2.075 2.173 1.530 0.0387978 piggyBac transposable element derived 2 TMEM185B 2.559 2.585 2.585 3.205 3.075 3.496 1.537 0.0434965 transmembrane protein 185B (pseudogene) NIN 5.461 5.391 5.473 6.712 6.027 6.092 1.553 0.0448880 ninein (GSK3B interacting protein) ZNF623 5.055 4.665 5.076 5.517 5.667 5.718 1.561 0.0469056 zinc finger protein 623 ZC3H12B 1.974 1.974 1.974 2.649 2.858 2.457 1.597 0.0405556 zinc finger CCCH-type containing 12B SERPINB8 6.188 6.520 6.332 6.999 6.875 7.313 1.610 0.0495625 serpin peptidase inhibitor, clade B (ovalbumin), member 8 SOCS6 5.226 4.781 5.252 5.965 5.666 5.925 1.639 0.0452333 suppressor of cytokine signaling 6 N4BP1 7.299 7.806 7.555 8.386 8.284 8.181 1.658 0.0449271 NEDD4 binding protein 1 IDH 8.143 7.875 8.242 8.877 8.780 8.913 1.663 0.0267744 Description LOC401093 4.360 4.237 4.606 5.117 4.973 5.226 1.666 0.0410568 No description LOC652276 4.304 4.282 3.868 4.825 5.047 4.856 1.673 0.0397913 No description LONRF2 4.331 3.944 3.912 5.022 4.841 4.667 1.688 0.0392264 LON peptidase N-terminal domain and ring finger 2 OXR1 6.439 6.600 6.553 7.065 7.309 7.938 1.689 0.0455249 oxidation resistance 1 L2HGDH 7.244 6.733 7.035 7.768 7.643 8.002 1.691 0.0396577 L-2-hydroxyglutarate dehydrogenase HN1L 9.635 10.345 10.255 11.105 10.762 11.019 1.698 0.0440714 hematological and neurological expressed 1−like EPB41L2 2.782 2.994 3.118 3.598 3.757 3.886 1.703 0.0282855 erythrocyte membrane protein band 4.1-like 2 C1orf27 6.526 6.700 6.503 7.300 7.796 7.201 1.710 0.0349509 chromosome 1 open reading frame 27 C14orf119 2.974 3.841 3.869 4.464 4.649 4.450 1.717 0.0466393 chromosome 14 open reading frame 119 PSMC6 8.916 8.961 8.143 9.631 9.741 9.603 1.717 0.0356692 proteasome (prosome, macropain) 26S subunit, ATPase, 6 CXorf36 3.539 3.214 3.497 4.514 3.907 4.286 1.728 0.0431965 chromosome X open reading frame 36 DGKA 7.202 7.066 7.408 7.950 8.207 7.859 1.733 0.0326147 diacylglycerol kinase, alpha 80 kDa DPY19L3 4.234 4.263 3.546 4.902 4.887 5.066 1.744 0.0353300 dpy-19-like 3 (C. elegans) LOC643008 3.747 3.412 3.471 4.107 4.290 4.906 1.764 0.0474305 No description PREPL 4.246 4.522 4.540 5.005 5.342 5.582 1.765 0.0321358 prolyl endopeptidase-like FAM120A 8.136 8.400 7.513 8.955 9.199 8.919 1.765 0.0347176 family with sequence similarity 120A COX 10 3.144 3.539 3.963 4.360 4.351 4.559 1.767 0.0456546 COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast) MRPS35 7.337 7.440 7.891 8.422 8.343 8.167 1.777 0.0496907 mitochondrial ribosomal protein S35 ZDHHC2 3.364 3.680 3.007 4.123 4.512 4.042 1.779 0.0446355 zinc finger, DHHC-type containing 2 IOCA1 2.974 2.994 2.974 3.484 3.809 4.280 1.783 0.0411543 IQ motif containing with AAA domain 1 SLFN13 5.626 4.999 5.484 6.219 6.464 6.287 1.787 0.0255004 schlafen family member 13 RAB14 10.094 10.845 10.747 11.684 11.339 11.410 1.789 0.0423576 RAB14, member RAS oncogene family CSPP1 5.109 5.002 4.964 5.537 6.075 5.843 1.791 0.0354152 centrosome and spindle pole associated protein 1 C20orf195 0.974 1.328 1.264 2.108 1.692 2.404 1.795 0.0413676 chromosome 20 open reading frame 195 USP8 5.613 6.690 5.854 7.562 7.377 6.696 2.118 0.0463078 ubiquitin specific peptidase 8 KDM2A 9.849 9.619 9.543 11.120 10.703 10.398 2.121 0.0203400 lysine (K)-specific demethylase 2A ARHGAP23 6.238 7.206 6.902 8.158 7.626 7.988 2.123 0.0301174 Rho GTPase activating protein 23 YTHDF2 9.980 10.923 11.412 12.301 12.010 11.818 2.125 0.0381773 YTH domain family, member 2 NSL1 4.412 4.688 4.766 5.504 6.022 5.562 2.132 0.0158005 NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) POMGNT1 7.487 8.077 8.241 9.293 9.172 8.927 2.135 0.0162049 protein O-linked mannose beta1,2-N- acetylglucosaminyltransferase GCDH 5.254 5.860 6.348 7.037 6.956 6.667 2.137 0.0400852 glutaryl-CoA dehydrogenase RTKN2 3.412 3.031 3.844 4.152 4.507 4.803 2.137 0.0339440 rhotekin 2 DAG LA 4.548 5.102 4.255 6.030 5.443 5.645 2.139 0.0328342 diacylglycerol lipase, alpha C19orf12 5.847 6.570 5.598 6.830 7.225 6.945 2.139 0.0448074 chromosome 19 open reading frame 12 PCBD2 5.664 5.318 5.540 6.762 6.694 6.244 2.140 0.0160483 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 REC8 5.012 5.478 5.471 6.110 6.149 6.588 2.140 0.0274006 REC8 homolog (yeast) ZNF518B 4.243 3.462 3.916 5.145 5.344 4.484 2.144 0.0362579 zinc finger protein 518B MGAT4A 4.546 4.914 4.334 5.866 5.437 5.679 2.148 0.0183369 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N- acetylglucosaminyltransferase, isozyme A ARF1 12.915 13.572 13.433 14.679 14.486 14.060 2.154 0.0242817 ADP-ribosylation factor 1 FAM153B 5.945 5.043 6.494 7.448 6.941 7.053 2.154 0.0349194 family with sequence similarity 153, member B ANKLE1 6.124 5.354 5.279 6.814 6.387 6.820 2.156 0.0317199 ankyrin repeat and LEM domain containing 1 PTGER2 2.296 2.448 2.675 3.784 3.751 3.043 2.157 0.0276470 prostaglandin E receptor 2 (subtype EP2), 53 kDa MRPS25 7.393 6.110 6.901 7.916 8.080 8.010 2.157 0.0335572 mitochondrial ribosomal protein S25 LOC285550 4.761 4.434 3.850 5.870 5.214 5.406 2.158 0.0301734 No description SFRS13A 7.067 6.180 6.918 7.769 8.033 8.049 2.166 0.0185625 No description MTMR9 4.183 5.172 5.154 6.287 6.003 5.886 2.167 0.0266754 myotubularin related protein 9 SLC30A4 2.974 3.665 3.189 4.696 4.091 4.721 2.168 0.0189102 solute carrier family 30 (zinc transporter), member 4 SFRS2IP 5.579 5.542 6.087 7.148 7.069 6.659 2.168 0.0130737 No description TNFSF10 9.032 8.641 9.174 10.507 9.976 9.761 2.173 0.0224589 tumor necrosis factor (ligand) superfamily, member 10 MTHFR 8.533 8.257 8.834 9.991 9.652 9.103 2.173 0.0372694 methylenetetrahydrofolate reductase (NAD(P)H) ATR 4.777 5.173 5.618 6.741 6.187 5.921 2.178 0.0381880 ataxia telangiectasia and Rad3 related RSAD1 2.559 2.825 2.663 3.685 4.110 3.683 2.179 0.0096017 radical S-adenosyl methionine domain containing 1 FGF5 4.984 4.282 5.293 5.860 6.212 6.110 2.183 0.0233292 fibroblast growth factor 5 ATP5E 0.974 0.974 0.974 2.108 1.692 2.878 2.193 0.0246654 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit TAF1A 0.974 1.328 0.974 2.108 2.848 1.819 2.193 0.0283530 TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48 kDa SLC13A3 3.220 2.747 3.927 4.899 4.353 4.222 2.193 0.0384858 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 RNF160 5.793 5.206 4.870 6.360 6.003 6.469 2.194 0.0433208 No description AS3MT 1.974 2.819 3.334 3.966 3.712 3.954 2.196 0.0420391 arsenic (+3 oxidation state) methyltransferase GGA2 6.106 5.609 5.881 7.354 6.746 6.997 2.199 0.0148672 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 CCDC115 5.584 5.848 4.242 6.844 6.231 6.722 2.201 0.0432226 coiled-coil domain containing 115 CILP 1.559 2.375 2.627 3.032 3.374 3.767 2.204 0.0348588 cartilage intermediate layer protein, nucleotide pyrophosphohydrolase NXF1 10.385 10.939 11.213 12.081 11.840 12.111 2.206 0.0184766 nuclear RNA export factor 1 NUFIP1 4.802 4.918 4.577 5.746 6.093 5.721 2.209 0.0110821 nuclear fragile X mental retardation protein interacting protein 1 ABL1 7.897 9.049 8.447 9.591 9.640 9.406 2.210 0.0391535 c-abl oncogene 1, non-receptor tyrosine kinase MDK 9.878 8.916 10.464 10.848 11.022 11.187 2.210 0.0419670 midkine (neurite growth-promoting factor 2) GPR143 0.974 0.974 1.050 2.108 1.692 1.819 1.795 0.0186969 G protein-coupled receptor 143 FBN2 0.974 1.050 0.974 2.404 1.692 1.819 1.795 0.0269593 fibrillin 2 RPL23AP82 1.559 1.559 1.759 2.404 2.075 2.650 1.795 0.0482003 ribosomal protein L23a pseudogene 82 CLCN5 2.974 3.206 2.994 3.825 3.934 4.033 1.804 0.0142916 chloride channel 5 LOC284232 7.744 7.871 7.936 8.723 8.573 8.860 1.805 0.0151297 No description COX 11 3.272 3.838 3.598 4.327 4.703 4.327 1.821 0.0342916 COX11 cytochrome c oxidase assembly homolog (yeast) MKLN1 8.236 7.011 8.324 8.907 9.078 9.193 1.826 0.0435748 muskelin 1, intracellular mediator containing kelch motifs CNGB1 2.944 2.880 2.296 3.469 3.817 3.680 1.831 0.0313530 cyclic nucleotide gated channel beta 1 ADAMTS1 3.764 3.448 3.448 4.263 4.321 5.028 1.831 0.0355403 ADAM metallopeptidase with thrombospondin type 1 motif, 1 MORF4L1 10.853 10.663 9.641 11.723 11.538 11.454 1.833 0.0365487 mortality factor 4 like 1 MRPL14 10.536 10.041 10.082 11.212 11.372 10.917 1.835 0.0267153 mitochondrial ribosomal protein L14 UBE2J1 9.593 9.063 9.474 10.749 10.313 9.946 1.844 0.0418688 ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) TCFL5 3.470 3.872 3.767 4.353 4.940 4.554 1.845 0.0311949 transcription factor-like 5 (basic helix-loop-helix) NSMCE4A 1.974 1.974 2.013 3.319 2.858 2.457 1.845 0.0438104 non-SMC element 4 homolog A (S. cerevisiae) IKBKB 7.860 7.701 7.608 8.585 8.375 8.953 1.846 0.0255457 inhibitor of kappa light polypeptide gene enhancer in B- cells, kinase beta TIMP4 1.974 1.974 1.974 4.168 2.858 2.860 1.847 0.0326616 TIMP metallopeptidase inhibitor 4 PAIP2B 1.974 1.974 2.406 2.860 3.334 2.860 1.847 0.0339332 poly(A) binding protein interacting protein 2B PRIC285 3.865 4.126 4.522 5.012 5.016 4.980 1.848 0.0374574 No description WDR1 11.174 11.641 11.096 12.145 12.158 11.983 1.849 0.0403929 WD repeat domain 1 TROVE2 7.575 8.205 8.467 9.012 9.355 9.019 1.850 0.0325894 TROVE domain family, member 2 TRIT1 4.572 4.637 4.107 5.262 5.667 4.997 1.854 0.0494973 tRNA isopentenyltransferase 1 RAD18 4.819 5.492 5.691 6.218 6.584 6.177 1.856 0.0401834 RAD18 homolog (S. cerevisiae) SGK196 1.559 1.559 1.559 2.194 2.454 2.650 1.859 0.0198550 No description C20orf20 5.824 5.408 5.263 6.391 6.166 6.338 1.869 0.0396470 chromosome 20 open reading frame 20 DGKZ 7.405 7.308 7.419 8.057 8.564 8.311 1.875 0.0182525 diacylglycerol kinase, zeta SORBS1 5.875 7.160 7.240 8.003 7.914 8.149 1.878 0.0396362 sorbin and SH3 domain containing 1 RNMTL1 5.584 6.625 6.511 7.461 7.093 7.421 1.880 0.0406992 RNA methyltransferase like 1 NARG2 2.782 2.974 3.419 4.133 3.704 3.886 1.881 0.0441151 NMDA receptor regulated 2 CBLL1 6.468 6.498 7.070 7.907 7.580 7.381 1.883 0.0363730 Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1 MYO19 6.846 6.789 6.516 7.431 7.622 7.805 1.886 0.0202064 myosin XIX CBARA1 6.747 6.299 6.513 7.651 7.607 7.217 1.890 0.0213645 calcium binding atopy-related autoantigen 1 PDE4D 3.144 3.144 3.161 4.183 4.066 3.605 1.894 0.0381036 phosphodiesterase 4D, cAMP-specific PPP2CB 11.603 11.058 11.557 11.870 12.479 12.719 1.895 0.0499470 protein phosphatase 2, catalytic subunit, beta isozyme NRM 4.631 4.478 4.887 6.683 5.410 5.541 1.908 0.0402701 nurim (nuclear envelope membrane protein) PIK302B 3.539 3.645 3.144 4.696 4.079 4.166 1.911 0.0463546 phosphoinositide-3-kinase, class 2, beta polypeptide CBX5 5.389 5.201 5.378 6.432 6.314 6.057 1.912 0.0142448 chromobox homolog 5 ZNF586 3.597 3.196 3.723 3.966 4.534 4.806 1.914 0.0498273 zinc finger protein 586 C6orf136 6.505 6.208 5.904 7.147 7.184 6.961 1.916 0.0285879 chromosome 6 open reading frame 136 HADHA 9.823 10.058 10.347 11.083 10.851 11.000 1.921 0.0231949 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit LOC1001339 5.236 4.801 4.290 5.744 5.647 6.010 1.923 0.0363837 No description 57 TPD52L2 9.569 10.358 10.302 11.249 11.152 11.256 1.928 0.0195311 tumor protein D52-like 2 ATP2A3 5.379 6.239 6.600 7.097 6.949 7.550 1.933 0.0474037 ATPase, Ca++ transporting, ubiquitous HBS1L 5.484 4.747 5.522 6.239 6.119 6.478 1.939 0.0317652 HBS1−like (S. cerevisiae) ZNF828 2.944 2.651 2.859 4.054 3.817 3.364 1.942 0.0318849 zinc finger protein 828 SYNE2 6.453 7.390 6.471 8.202 7.411 8.072 1.943 0.0455418 spectrin repeat containing, nuclear envelope 2 TRIM26 9.248 9.483 9.956 10.298 10.835 10.443 1.945 0.0370015 tripartite motif-containing 26 MAFF 8.507 6.503 8.445 9.215 9.363 9.468 1.947 0.0495518 v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) IPP 3.908 3.679 4.408 5.369 5.084 4.570 1.947 0.0435434 intracisternal A particle-promoted polypeptide C10orf104 8.061 7.557 7.891 9.025 8.688 8.756 1.950 0.0191266 No description YTHDF3 7.305 7.183 6.185 8.185 7.657 8.149 1.954 0.0476285 YTH domain family, member 3 TRPM7 6.118 6.335 5.327 6.914 6.755 7.304 1.957 0.0427805 transient receptor potential cation channel, subfamily M, member 7 WNK1 7.432 7.803 7.725 8.696 8.403 8.875 1.960 0.0176009 WNK lysine deficient protein kinase 1 NCRNA00201 3.927 4.074 3.656 4.685 4.950 4.898 1.960 0.0159701 non-protein coding RNA 201 C6orf64 5.545 6.564 6.253 7.330 7.224 6.871 1.960 0.0452824 chromosome 6 open reading frame 64 TCEB3 7.218 8.241 8.230 9.213 8.979 9.055 1.961 0.0296470 transcription elongation factor B (SIH), polypeptide 3 (110 kDa, elong in A) SCAPER 2.782 2.782 3.351 3.900 3.704 4.327 1.967 0.0323170 S-phase cyclin A-associated protein in the ER HTRA4 5.908 5.446 4.853 6.598 6.422 6.248 1.967 0.0428281 HtrA serine peptidase 4 HMGN4 7.103 7.579 6.748 8.081 8.268 7.951 1.970 0.0367398 high mobility group nucleosomal binding domain 4 TEAD4 6.906 7.536 7.783 8.205 8.440 8.768 1.980 0.0348427 TEA domain family member 4 LSS 4.546 4.166 4.304 5.531 4.983 5.386 1.980 0.0237636 lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) KIAA2026 4.884 5.103 4.417 5.826 5.871 5.961 1.982 0.0164697 KIAA2026 NUDT21 7.626 7.236 6.885 8.614 8.188 8.017 1.983 0.0330338 nudix (nucleoside diphosphate linked moiety X)-type motif 21 METTL7A 7.348 6.589 6.619 8.083 7.798 7.577 1.984 0.0422287 methyltransferase like 7A C12orf34 2.559 3.061 3.564 4.050 4.367 3.942 1.985 0.0371105 chromosome 12 open reading frame 34 SLC23A2 5.403 5.716 5.775 6.462 6.934 6.392 1.985 0.0249447 solute carrier family 23 (nucleobase transporters), member 2 CXCL12 2.782 3.483 3.026 4.049 4.018 3.963 1.989 0.0306539 chemokine (C-X-C motif) ligand 12 FBXL18 5.436 5.051 5.533 6.076 6.174 6.526 1.991 0.0284436 F-box and leucine-rich repeat protein 18 FNIP1 7.304 6.727 6.612 7.807 7.634 7.721 1.992 0.0440437 folliculin interacting protein 1 PIK3CA 4.870 5.276 4.050 5.865 5.615 6.047 1.993 0.0444106 phosphoinositide-3-kinase, catalytic, alpha polypeptide GSN 9.736 10.492 10.715 11.711 11.375 11.294 1.994 0.0291681 gelsolin RIT1 7.569 7.011 6.236 8.008 7.910 8.252 1.995 0.0473876 Ras-like without CAAX 1 SHISA9 3.117 2.804 2.610 3.907 3.802 3.787 1.998 0.0151190 shisa homolog 9 (Xenopus laevis) KANK2 2.782 3.006 2.782 3.999 4.005 3.616 1.998 0.0133269 KN motif and ankyrin repeat domains 2 ZXDC 7.622 7.713 8.148 9.013 8.712 8.655 1.998 0.0231543 ZXD family zinc finger C C12orf5 5.036 4.820 5.365 6.094 6.035 5.986 1.999 0.0177575 chromosome 12 open reading frame 5 ABCF1 7.839 7.944 8.575 8.839 9.253 9.240 2.000 0.0345664 ATP-binding cassette, sub-family F (GCN20), member 1 STK25 6.176 6.738 6.554 7.391 7.617 7.554 2.000 0.0159540 serine/threonine kinase 25 GPATCH8 4.062 4.685 5.139 5.697 5.675 5.829 2.016 0.0320015 G patch domain containing 8 BTBD10 5.954 6.800 6.921 7.442 7.934 7.623 2.017 0.0355295 BTB (POZ) domain containing 10 COL4A3BP 4.169 4.544 4.174 5.337 5.082 5.558 2.018 0.0169517 collagen, type IV, alpha 3 (Goodpasture antigen) binding protein C6orf48 9.544 8.706 9.011 9.791 9.945 10.559 2.021 0.0484635 chromosome 6 open reading frame 48 EXOSC7 4.548 4.666 4.608 5.623 5.362 5.832 2.021 0.0132072 exosome component 7 MDM4 7.005 6.924 7.670 8.548 8.332 7.943 2.026 0.0309954 Mdm4 p53 binding protein homolog (mouse) PSMA7 11.067 11.439 10.870 12.209 12.245 11.889 2.026 0.0221197 proteasome (prosome, macropain) subunit, alpha type, 7 SENP7 2.974 3.013 3.013 4.032 3.809 4.141 2.027 0.0091197 SUMO1/sentrin specific peptidase 7 C13orf1 5.171 5.128 4.645 6.477 5.667 5.937 2.031 0.0334766 chromosome 13 open reading frame 1 CCNL1 9.234 8.723 8.476 9.749 9.590 10.144 2.036 0.0338058 cyclin L1 ZSWIM7 4.475 4.642 4.623 5.649 5.778 5.171 2.037 0.0234305 zinc finger, SWIM-type containing 7 SIP1 4.054 4.998 4.576 6.025 5.451 5.386 2.038 0.0394298 survival of motor neuron protein interacting protein 1 CPNE2 6.996 8.955 9.071 9.975 10.099 9.864 2.040 0.0416339 copine II C16orf54 4.662 3.304 4.207 5.454 5.066 5.236 2.040 0.0410322 chromosome 16 open reading frame 54 GEN1 3.296 3.388 3.540 5.104 4.419 4.270 2.043 0.0180292 Gen homolog 1, endonuclease (Drosophila) KIAA0892 7.012 8.324 8.437 9.356 9.377 8.891 2.044 0.0443308 No description CEP170 2.559 2.635 2.559 3.673 3.591 3.205 2.045 0.0197107 centrosomal protein 170 kDa LMTK2 8.028 6.918 7.740 8.999 8.772 8.621 2.045 0.0261604 lemur tyrosine kinase 2 DCAF6 5.810 5.439 5.132 6.354 6.166 6.907 2.047 0.0378887 DDB1 and CUL4 associated factor 6 BST2 7.789 7.312 7.926 8.789 8.824 8.827 2.049 0.0120445 bone marrow stromal cell antigen 2 FRK 1.974 2.228 2.161 2.825 3.196 3.376 2.049 0.0172939 fyn-related kinase PMS2L5 2.247 2.432 2.878 3.324 3.478 3.469 2.051 0.0286155 No description GTF2B 7.320 7.475 7.761 8.790 8.690 8.356 2.051 0.0136639 general transcription factor I IB GLO1 11.439 11.459 11.984 13.022 12.985 12.270 2.053 0.0269701 glyoxalase I AP3S1 1.974 2.673 1.974 2.860 3.712 3.220 2.055 0.0421120 adaptor-related protein complex 3, sigma 1 subunit MST1R 5.198 5.339 4.676 5.851 6.266 6.239 2.057 0.0239862 macrophage stimulating 1 receptor (c-met-related tyrosine kinase) LOC147804 3.117 3.205 3.948 4.991 4.651 4.126 2.060 0.0348235 No description GSTCD 3.908 3.858 3.351 4.784 4.775 4.951 2.060 0.0124551 glutathione S-transferase, C-terminal domain containing NT5C2 7.515 7.235 6.500 8.279 8.192 8.452 2.061 0.0216938 5′-nucleotidase, cytosolic II MRPS7 7.836 8.331 8.760 9.334 9.806 8.980 2.066 0.0454152 mitochondrial ribosomal protein S7 RBM23 7.989 8.236 8.531 9.309 9.411 9.037 2.068 0.0199547 RNA binding motif protein 23 ZNF516 5.189 4.917 4.343 5.959 6.038 5.969 2.074 0.0171404 zinc finger protein 516 MGC16384 4.605 3.616 3.966 4.938 5.023 5.462 2.080 0.0378097 No description PDE1C 0.974 1.050 1.264 2.108 1.692 3.304 2.082 0.0469893 phosphodiesterase 1C, calmodulin-dependent 70 kDa FLVCR1 4.290 4.187 4.445 5.348 5.616 5.112 2.083 0.0134321 feline leukemia virus subgroup C cellular receptor 1 LOC344967 7.698 6.695 7.336 8.397 8.491 7.899 2.087 0.0489540 No description STARD3NL 6.984 7.219 6.792 8.048 8.382 7.549 2.090 0.0351435 STARD3 N-terminal like POLH 6.454 6.537 7.182 8.073 7.895 7.518 2.092 0.0259785 polymerase (DNA directed), eta CKB 10.487 9.524 10.643 11.416 11.480 11.709 2.093 0.0222433 creatine kinase, brain HERC5 2.296 2.357 2.296 2.859 3.469 3.364 2.097 0.0265081 hect domain and RLD 5 DES 1.974 3.247 2.953 3.525 4.022 4.106 2.097 0.0475641 desmin ABI2 4.419 4.304 4.614 6.071 5.487 5.289 2.097 0.0174275 abl-interactor 2 CRABP2 12.413 11.687 12.663 13.325 13.521 13.483 2.100 0.0222180 cellular retinoic acid binding protein 2 MRPL33 9.961 9.581 9.654 11.257 10.725 10.372 2.102 0.0308028 mitochondrial ribosomal protein L33 LAMB3 6.462 8.067 7.577 8.394 8.649 8.844 2.102 0.0487736 laminin, beta 3 TRPS1 7.517 7.435 7.600 8.796 8.592 8.057 2.106 0.0287521 trichorhinophalangeal syndrome I SEC31A 10.791 9.850 10.470 11.212 11.871 11.494 2.114 0.0305710 SEC31 homolog A (S. cerevisiae) PPP3CC 6.061 6.807 6.831 7.374 7.637 7.912 2.116 0.0313722 protein phosphatase 3, catalytic subunit, gamma isozyme SLC25A26 8.043 7.492 7.146 8.447 8.637 8.678 2.212 0.0311282 solute carrier family 25, member 26 FAM55C 6.767 5.923 6.732 7.918 7.408 7.355 2.221 0.0364259 family with sequence similarity 55, member C TTL 6.092 6.896 6.620 8.049 7.618 7.435 2.224 0.0236899 tubulin tyrosine ligase RAB6A 3.687 5.634 5.336 6.642 6.490 6.310 2.226 0.0365318 RAB6A, member RAS oncogene family CDH17 0.974 1.692 2.142 2.848 2.848 2.348 2.228 0.0481842 cadherin 17, LI cadherin (liver-intestine) UPP2 5.908 6.089 6.087 6.479 7.349 7.245 2.232 0.0368619 uridine phosphorylase 2 PABPN1 9.887 8.951 9.401 10.276 10.560 10.745 2.233 0.0286769 poly(A) binding protein, nuclear 1 ESRP2 6.109 6.698 6.422 7.352 7.809 7.583 2.237 0.0135372 epithelial splicing regulatory protein 2 HTATSF1 3.272 2.847 3.611 4.768 4.434 4.327 2.237 0.0137652 HIV-1 Tat specific factor 1 FAM3C 4.169 5.097 5.153 5.982 6.317 6.201 2.241 0.0169854 family with sequence similarity 3, member C KCTD12 4.902 4.987 4.022 5.934 5.741 6.151 2.242 0.0193715 potassium channel tetramerisation domain containing 12 BID 8.015 7.416 7.651 8.581 8.881 9.011 2.242 0.0152686 BH3 interacting domain death agonist CHMP4C 6.450 6.122 6.151 8.128 7.316 7.048 2.242 0.0233983 chromatin modifying protein 4C PPP1R13L 10.629 9.373 10.168 11.318 11.129 11.794 2.243 0.0266946 protein phosphatase 1, regulatory (inhibitor) subunit 13 like CCDC86 6.710 7.569 8.083 8.537 8.902 8.735 2.244 0.0333845 coiled-coil domain containing 86 CHST6 6.709 6.068 6.849 7.875 7.959 7.439 2.245 0.0194398 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 MAP 3.656 3.485 3.781 5.042 4.259 4.823 2.245 0.0234835 v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) LYN 9.403 8.689 8.086 9.958 9.857 9.670 2.247 0.0472809 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog RRAGA 8.594 9.369 9.237 10.541 10.177 9.808 2.253 0.0323062 Ras-related GTP binding A PDZRN3 2.747 2.162 2.126 3.196 3.334 3.954 2.254 0.0262602 PDZ domain containing ring finger 3 DECR2 7.625 7.978 8.812 9.151 9.583 9.104 2.254 0.0410215 2,4-dienoyl CoA reductase 2, peroxisomal ADO 4.631 6.309 6.471 7.279 7.527 7.483 2.257 0.0314743 2-aminoethanethiol (cysteamine) dioxygenase PARD6G 4.215 4.376 4.417 5.344 5.553 5.677 2.262 0.0050261 par-6 partitioning defective 6 homolog gamma (C. elegans) SNTB2 6.533 6.599 6.998 7.778 7.755 8.174 2.265 0.0111896 syntrophin, beta 2 (dystrophin-associated protein A1, 59 kDa, basic component 2) UNC45A 7.649 8.270 8.322 9.502 9.152 9.216 2.266 0.0144328 unc-45 homolog A (C. elegans) RAGE 6.882 6.377 6.571 8.063 7.887 7.183 2.267 0.0305564 renal tumor antigen ADAMTS9 6.684 7.025 6.092 7.869 7.530 8.175 2.275 0.0219179 ADAM metallopeptidase with thrombospondin type 1 motif, 9 HCCS 7.808 7.014 7.639 8.830 8.888 8.811 2.283 0.0095702 holocytochrome c synthase C9orf123 6.747 7.100 6.526 7.935 8.128 7.939 2.284 0.0090737 chromosome 9 open reading frame 123 TNRC6B 6.101 6.342 6.068 7.701 7.294 6.778 2.287 0.0271205 trinucleotide repeat containing 6B POLR2A 9.070 9.572 8.592 10.766 10.173 10.153 2.288 0.0223638 polymerase (RNA) II (DNA directed) polypeptide A, 220 kDa SLC37A1 7.654 8.854 8.704 10.048 9.786 9.340 2.288 0.0316378 solute carrier family 37 (glycerol-3-phosphate transporter), member 1 USP2 4.450 3.117 3.861 5.096 5.013 5.059 2.295 0.0309056 ubiquitin specific peptidase 2 JAGN1 6.809 8.074 8.044 9.273 8.892 8.478 2.296 0.0479862 jagunal homolog 1 (Drosophila) TRIM5 5.493 5.204 4.782 6.576 6.352 6.404 2.298 0.0096915 tripartite motif-containing 5 MAPRE2 3.764 3.766 4.220 5.181 4.968 5.295 2.303 0.0086055 microtubule-associated protein, RP/EB family, member 2 UTS2D 1.559 3.077 3.552 4.705 4.282 4.144 2.305 0.0341550 urotensin 2 domain containing B4GALT6 1.974 3.051 2.377 3.263 3.583 3.637 2.306 0.0451750 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 GATS 4.059 5.637 5.317 6.843 6.474 6.122 2.308 0.0332494 GATS, stromal antigen 3 opposite strand LOC254559 1.974 2.347 2.126 4.758 3.334 2.860 2.310 0.0391919 No description AASDHPPT 5.232 5.616 4.543 6.049 6.713 6.441 2.312 0.0261796 aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase GN AZ 2.519 4.364 3.778 4.989 4.765 5.200 2.315 0.0421535 guanine nucleotide binding protein (G protein), alpha z polypeptide SLC25A43 6.140 6.738 6.433 7.353 7.959 7.367 2.317 0.0217391 solute carrier family 25, member 43 AVPH 6.304 5.797 5.864 7.534 7.078 6.630 2.320 0.0311581 arginine vasopressin-induced 1 NDUFS2 3.117 2.881 3.360 4.422 4.344 4.099 2.325 0.0094259 NADH dehydrogenase (ubiquinone) Fe-S protein 2. 49 kDa (NADH-coenzyme Q reductase) AFTPH 8.844 8.281 7.799 9.313 9.473 10.062 2.325 0.0250307 aftiphilin GGNBP2 8.968 8.406 8.194 9.604 9.627 9.938 2.331 0.0161305 gametogenetin binding protein 2 CARD10 7.059 7.253 7.671 8.280 8.513 8.785 2.331 0.0140883 caspase recruitment domain family, member 10 CLEC4E 1.974 2.013 2.013 4.899 3.196 3.220 2.332 0.0207145 C-type lectin domain family 4, member E GPR115 1.974 1.974 1.974 3.196 3.196 2.457 2.332 0.0319010 G protein-coupled receptor 115 LOC349196 4.621 4.909 4.735 6.053 5.601 6.131 2.334 0.0106431 No description MAP3K4 4.719 4.772 4.738 5.964 5.672 6.373 2.338 0.0094045 mitogen-activated protein kinase kinase kinase 4 NONO 10.191 8.872 10.369 11.478 11.417 10.905 2.339 0.0322157 non-POU domain containing, octamer-binding C11orf75 3.475 3.539 3.771 4.471 4.765 5.330 2.339 0.0148135 chromosome 11 open reading frame 75 CENPO 1.974 4.388 4.547 5.758 5.615 5.136 2.341 0.0474658 centromere protein O PTAR1 6.474 6.290 5.577 7.265 7.701 7.213 2.342 0.0188457 protein prenyltransferase alpha subunit repeat containing 1 AKAP11 2.559 3.358 3.205 5.223 4.030 3.787 2.342 0.0461335 A kinase (PRKA) anchor protein 11 LCORL 2.559 3.637 2.840 4.137 4.255 3.787 2.342 0.0462164 ligand dependent nuclear receptor corepressor-like MTA3 8.077 7.610 8.628 9.418 9.305 8.949 2.342 0.0324743 metastasis associated 1 family, members TAF11 6.967 7.249 6.861 8.197 8.135 8.341 2.346 0.0057560 TAF11 RNA polymerase II, TATA box binding protein (TBP)- associated factor, 28 kDa POLG 9.646 9.452 10.300 10.829 11.124 10.878 2.348 0.0214106 polymerase (DNA directed), gamma ISOC2 6.066 7.113 7.209 8.347 8.417 7.732 2.352 0.0271811 isochorismatase domain containing 2 RAB36 3.706 3.343 3.126 4.683 4.939 4.296 2.352 0.0139800 RAB36, member RAS oncogene family CYP2R1 6.242 6.098 7.185 7.915 8.018 7.332 2.352 0.0336124 cytochrome P450, family 2, subfamily R, polypeptide 1 F12 6.339 5.171 5.761 7.109 7.293 6.406 2.354 0.0465625 coagulation factor XII (Hageman factor) AKAP5 1.974 2.162 2.406 3.643 2.858 3.565 2.357 0.0205564 A kinase (PRKA) anchor protein 5 C20orf4 5.470 5.341 6.779 7.965 7.558 6.578 2.357 0.0447659 chromosome 20 open reading frame 4 C11orf52 5.376 5.483 5.107 7.359 6.322 6.616 2.361 0.0134129 chromosome 11 open reading frame 52 MEIS3P1 3.709 4.554 3.875 5.128 4.950 5.399 2.364 0.0263177 Meis homeobox 3 pseudogene 1 ZBTB39 2.974 3.943 4.085 5.327 4.396 5.164 2.366 0.0374467 zinc finger and BTB domain containing 39 SLC14A1 7.489 6.415 7.857 8.398 8.618 9.101 2.369 0.0287245 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) GPR56 2.782 3.188 3.616 4.133 4.706 4.434 2.371 0.0190660 G protein-coupled receptor 56 TMEM169 3.649 3.616 2.912 5.020 4.443 4.158 2.372 0.0338688 transmembrane protein 169 C19orf70 8.013 7.575 8.637 9.260 9.360 9.089 2.373 0.0270161 chromosome 19 open reading frame 70 DDHD2 4.804 5.028 5.207 6.275 6.495 5.839 2.374 0.0137099 DDHD domain containing 2 DFFB 3.117 3.238 4.145 4.902 4.485 4.473 2.374 0.0375288 DNA fragmentation factor, 40 kDa, beta polypeptide (caspase-activated DNase) TMTC1 5.127 4.282 4.457 5.554 5.706 6.142 2.378 0.0247805 transmembrane and tetratricopeptide repeat containing 1 MYO10 7.878 8.053 7.966 9.304 9.253 9.033 2.380 0.0035150 myosin X KIAA0649 6.098 6.051 5.844 7.213 7.350 7.300 2.382 0.0026124 KIAA0649 DDA1 10.017 10.336 11.472 12.461 12.669 11.270 2.383 0.0434229 DET1 and DDB1 associated 1 TECR 9.846 9.578 10.232 11.486 11.246 10.688 2.384 0.0189210 trans-2,3-enoyl-CoA reductase GBGT1 4.290 3.827 4.054 5.540 5.545 4.946 2.387 0.0113945 globoside alpha-1.3-N-acetylgalactosaminyltransferase 1 BCSIL 1.974 2.162 2.126 4.020 3.383 3.141 2.389 0.0094766 BCS1−like (S. cerevisiae) VCAM1 1.559 3.059 2.602 3.187 3.859 4.144 2.390 0.0479432 vascular cell adhesion molecule 1 ZNF845 1.913 3.335 3.974 4.592 4.657 4.592 2.390 0.0402487 zinc finger protein 845 ARPC5 5.678 7.423 6.601 8.405 7.668 7.860 2.393 0.0427698 actin related protein 2/3 complex, subunit 5, 16 kDa FAM114A1 3.637 4.308 3.367 5.570 4.747 4.842 2.398 0.0273292 family with sequence similarity 114, member A1 SHE 4.088 4.366 4.725 5.770 5.631 5.581 2.403 0.0085948 Src homology 2 domain containing E NHLRC1 3.220 3.578 3.571 4.572 5.214 4.486 2.406 0.0125917 NHL repeat containing 1 YY1AP1 7.712 7.733 7.207 8.475 8.547 9.501 2.408 0.0254021 YY1 associated protein 1 C11orf54 5.592 6.349 6.160 7.786 6.861 7.098 2.409 0.0291504 chromosome 11 open reading frame 54 ITGAL 1.974 1.974 2.953 4.222 4.222 3.220 2.410 0.0198657 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) SPR 4.042 4.854 4.370 6.123 6.055 5.059 2.410 0.0293653 sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) CASP8 6.145 7.706 7.623 8.692 8.976 8.621 2.412 0.0240161 caspase 8. apoptosis-related cysteine peptidase LRRC47 3.272 5.520 5.664 6.934 6.693 6.174 2.413 0.0480606 leucine rich repeat containing 47 NFXL1 3.364 3.567 2.627 4.637 4.811 4.422 2.416 0.0118872 nuclear transcription factor, X-box binding-like 1 LOCI 002165 4.984 3.389 5.427 6.427 6.111 6.260 2.423 0.0329916 No description 45 PRRG1 5.201 5.605 5.891 6.885 6.787 6.953 2.427 0.0084873 proline rich Gla (G-carboxyglutamic acid) 1 MAPKSP1 8.097 7.025 7.473 8.921 8.561 8.753 2.428 0.0244098 MAPK scaffold protein 1 LOC641 367 0.974 2.108 1.832 3.388 2.712 2.777 2.429 0.0275265 No description PLLP 5.991 5.525 4.712 6.929 6.806 6.310 2.429 0.0341719 plasmolipin METT11D1 8.582 8.836 9.678 10.192 10.062 10.117 2.431 0.0367229 methyltransferase 11 domain containing 1 TSPYL2 10.969 9.365 10.694 12.198 11.172 11.977 2.434 0.0458296 TSPY-like 2 ZBTB7C 4.205 5.546 4.741 6.190 6.025 5.920 2.436 0.0360200 zinc finger and BTB domain containing 7C POM121 4.208 3.825 4.128 5.413 6.042 5.095 2.437 0.0107728 POM121 membrane glycoprotein CSF1 5.211 4.889 4.945 6.496 6.333 6.160 2.437 0.0042510 colony stimulating factor 1 (macrophage) SEC22B 6.651 7.075 6.686 8.410 7.972 7.456 2.439 0.0268120 SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) NSFL1C 10.111 9.868 11.340 12.348 12.166 11.155 2.440 0.0452717 NSFL1 (p97) cofactor (p47) PSD 1.974 2.013 3.051 3.263 4.098 3.660 2.443 0.0306124 pleckstrin and Sec7 domain containing RIPK4 4.892 4.256 4.523 5.812 5.163 6.228 2.444 0.0329470 receptor-interacting serine-threonine kinase 4 C15orf17 6.961 7.137 7.435 7.966 8.450 8.726 2.446 0.0167744 chromosome 15 open reading frame 17 OAMK2D 5.583 4.746 4.316 6.605 5.609 6.459 2.450 0.0383246 calcium/calmodulin-dependent protein kinase II delta C9orf5 5.539 6.048 6.943 7.649 7.342 7.062 2.451 0.0497099 chromosome 9 open reading frame 5 ZBTB5 7.488 6.203 7.048 8.271 8.342 8.462 2.452 0.0178181 zinc finger and BTB domain containing 5 TTLL4 9.505 8.568 8.396 10.449 10.024 9.694 2.458 0.0360576 tubulin tyrosine ligase-like family, member 4 JRK 5.282 6.277 6.841 6.975 7.576 7.736 2.461 0.0482233 jerky homolog (mouse) MLH1 3.859 5.068 4.340 5.640 5.454 5.908 2.463 0.0292164 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) SMYD4 5.799 5.865 6.138 7.229 7.100 7.438 2.464 0.0043032 SET and MYND domain containing 4 SLCO4A1 2.782 3.792 3.025 5.291 4.327 3.886 2.466 0.0481282 solute carrier organic anion transporter family, member 4A1 POLDIP3 8.617 7.793 7.143 9.097 9.000 9.310 2.468 0.0359609 polymerase (DNA-directed), delta interacting protein 3 AATF 5.040 6.282 5.618 6.871 6.921 6.985 2.468 0.0243883 apoptosis antagonizing transcription factor RUNX3 5.909 6.592 6.563 7.714 7.896 7.714 2.469 0.0074022 runt-related transcription factor 3 PIP4K2B 4.085 4.420 4.196 5.724 5.194 5.699 2.470 0.0081236 phosphatidylinositol-5-phosphate 4-kinase, type II, beta YIPF4 6.100 6.407 5.317 7.265 7.510 7.405 2.471 0.0134682 Yip1 domain family, member 4 REV1 5.724 5.873 6.713 7.341 7.444 7.030 2.472 0.0287629 REV1 homolog (S. cerevisiae) RANBP9 8.394 7.821 7.439 9.558 8.831 9.127 2.472 0.0224889 RAN binding protein 9 ZNF521 2.559 3.061 2.559 4.622 3.648 3.869 2.478 0.0195503 zinc finger protein 521 EAPP 6.405 7.567 6.653 8.171 7.991 7.715 2.479 0.0470153 E2F-associated phosphoprotein RRN3P3 9.906 9.937 9.889 11.500 11.216 10.649 2.479 0.0152579 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 3 REEP4 6.422 6.683 7.484 7.995 8.494 7.738 2.482 0.0346930 receptor accessory protein 4 CUL2 7.201 6.507 6.239 7.821 8.187 7.634 2.486 0.0235134 cullin 2 KCNH8 2.747 3.388 2.649 3.868 4.627 4.703 2.487 0.0144543 potassium voltage-gated channel, subfamily H (eag- related), member 8 GOLGB1 7.634 7.773 7.435 9.088 8.632 8.953 2.488 0.0064121 golgin B1 MIF4GD 5.514 5.490 5.502 6.818 7.270 5.932 2.490 0.0393753 MIF4G domain containing TIPIN 2.878 3.089 2.531 4.321 4.406 3.758 2.491 0.0116915 TIMELESS interacting protein DIAPH3 2.296 2.859 2.859 4.054 4.178 4.042 2.495 0.0050683 diaphanous homolog 3 (Drosophila) SLC28A3 4.153 3.758 3.900 5.475 5.383 4.717 2.499 0.0148457 solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 GRPEL1 7.862 8.122 8.179 9.294 9.501 9.418 2.500 0.0029371 GrpE-like 1, mitochondrial (E. coli) CEBPB 12.579 13.013 12.426 13.640 13.901 14.449 2.501 0.0149225 CCAAT/enhancer binding protein (C/EBP), beta CYP27C1 5.087 5.433 6.365 7.231 7.053 6.410 2.501 0.0406408 cytochrome P450, family 27, subfamily C, polypeptide 1 CTCF 4.779 6.086 5.032 7.200 6.473 6.104 2.505 0.0490138 CCCTC-binding factor (zinc finger protein) RBM15B 6.944 7.438 8.130 9.033 8.763 8.325 2.505 0.0376723 RNA binding motif protein 15B CETN2 8.366 8.051 7.147 9.384 9.378 8.898 2.508 0.0239655 centrin, EF-hand protein, 2 C9orf80 6.203 5.752 6.466 7.793 7.415 7.318 2.509 0.0100368 chromosome 9 open reading frame 80 RHEBL1 2.878 2.752 3.089 3.469 4.207 4.801 2.512 0.0323807 Ras homolog enriched in brain like 1 ZSCAN16 4.054 4.312 5.383 6.371 6.133 5.386 2.518 0.0379923 zinc finger and SCAN domain containing 16 RAB2B 5.107 4.238 5.371 6.705 6.228 6.211 2.521 0.0162985 RAB2B, member RAS oncogene family ASCC1 6.485 6.707 6.454 8.605 7.820 7.320 2.522 0.0218880 activating signal cointegrator 1 complex subunit 1 ST3GAL5 1.913 2.038 2.636 3.974 3.825 3.152 2.528 0.0137398 STS beta-galactoside alpha-2,3-sialyltransferase 5 CBX7 4.821 5.488 4.848 7.024 6.188 6.151 2.531 0.0176546 chromobox homolog 7 PAR5 5.125 4.370 5.404 5.711 7.012 5.997 2.532 0.0489432 No description RAP1GDS1 2.559 4.550 4.314 5.476 5.895 4.939 2.539 0.0439447 RAP1. GTP-GDP dissociation stimulator 1 C9orf78 6.392 8.040 7.291 9.029 8.512 8.637 2.542 0.0293239 chromosome 9 open reading frame 78 PARG 5.048 5.375 5.169 6.511 6.446 6.721 2.543 0.0032134 poly (ADP-ribose) glycohydrolase IDE 5.944 6.890 6.385 7.915 8.238 7.136 2.545 0.0281972 Description C1orf21 8.690 7.456 7.727 8.805 9.136 9.274 2.548 0.0478465 chromosome 1 open reading frame 21 EFNB3 6.087 5.860 6.755 7.563 7.213 7.549 2.554 0.0201082 ephrin-B3 BRP44 0.974 1.050 1.050 2.404 1.692 3.304 2.557 0.0277038 brain protein 44 CCDC55 7.769 7.031 8.009 9.364 8.999 8.562 2.558 0.0208074 coiled-coil domain containing 55 SYNPO 4.296 5.311 5.039 6.395 6.072 6.452 2.560 0.0138450 synaptopodin RNF145 9.825 8.940 8.623 10.297 10.060 10.362 2.562 0.0421282 ring finger protein 145 SLC25A22 4.793 4.313 4.398 6.037 6.150 5.273 2.562 0.0166938 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 SF3B2 8.997 8.832 8.781 10.324 10.355 9.382 2.564 0.0293070 splicing factor 3b, subunit 2, 145 kDa SART1 8.474 7.721 8.977 9.835 10.041 9.729 2.568 0.0159432 squamous cell carcinoma antigen recognized by T cells SURF2 2.247 2.108 3.021 3.469 4.507 3.469 2.569 0.0313998 surfeit 2 TUSC1 7.051 8.043 7.108 8.698 8.414 8.481 2.572 0.0325365 tumor suppressor candidate 1 PSMD1 9.642 10.655 10.179 12.019 11.556 10.897 2.575 0.0318557 proteasome (prosome, macropain) 26S subunit, non- ATPase, 1 PPID 3.247 3.090 3.724 4.612 4.436 5.403 2.575 0.0146094 peptidylprolyl isomerase D PIGS 6.985 7.319 6.298 8.695 8.350 7.551 2.576 0.0344413 phosphatidylinositol glycan anchor biosynthesis, class S PAPL 8.713 8.326 8.955 10.321 10.058 9.726 2.578 0.0097253 No description KRBA2 8.158 7.357 8.709 9.979 9.525 8.987 2.579 0.0319348 KRAB-A domain containing 2 NFYA 7.953 7.703 8.413 9.165 9.320 9.568 2.580 0.0100875 nuclear transcription factor Y, alpha LOC84740 2.559 2.559 2.559 3.802 3.927 4.904 2.581 0.0091819 No description GLIPR1L2 3.247 2.901 3.335 4.707 4.038 4.683 2.588 0.0117682 GLI pathogenesis-related 1 like 2 RFXANK 7.705 7.623 8.961 10.338 10.187 8.907 2.598 0.0299770 regulatory factor X-associated ankyrin-containing protein TSRI 4.566 4.395 3.988 6.003 5.773 4.944 2.598 0.0265618 TSR1,20S rRNA accumulation, homolog (S. cerevisiae) DPY30 5.171 6.115 5.163 6.707 6.665 6.542 2.600 0.0279025 dpy-30 homolog (C. elegans) C3orf1 7.255 6.208 6.001 7.967 7.828 7.379 2.600 0.0386815 chromosome 3 open reading frame 1 POU2F2 3.144 4.764 5.330 6.143 5.608 6.164 2.601 0.0495733 POU class 2 homeobox 2 SMC4 3.616 3.998 3.730 4.999 5.067 5.541 2.607 0.0056738 structural maintenance of chromosomes 4 MCM2 5.823 5.419 6.041 7.480 7.205 6.770 2.608 0.0109493 minichromosome maintenance complex component 2 CALU 8.743 8.338 8.315 10.126 9.855 9.232 2.609 0.0175656 calumenin LOC729603 7.575 6.840 5.850 8.871 7.801 8.223 2.609 0.0370414 No description GMPS 7.213 6.436 5.967 7.821 8.057 7.669 2.611 0.0251090 guanine monphosphate synthetase ATM IN 5.569 6.587 6.101 7.810 7.487 7.209 2.613 0.0153338 ATM interactor PRDX6 10.103 10.212 10.096 11.872 11.495 11.351 2.625 0.0035257 peroxiredoxin 6 SYNGR1 6.635 5.880 7.383 8.503 8.028 7.579 2.626 0.0369117 synaptogyrin 1 INPP5A 4.719 6.190 5.431 7.098 6.730 6.824 2.627 0.0243715 inositol polyphosphate-5-phosphatase, 40 kDa IGF1 4.450 5.091 6.018 6.893 6.487 6.436 2.630 0.0308565 insulin-like growth factor 1 (somatomedin C) RGMA 6.160 6.709 5.992 7.812 8.037 7.389 2.634 0.0100077 RGM domain family, member A SERPINH1 6.604 7.734 7.382 8.177 8.357 9.132 2.636 0.0344221 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) FAM126A 2.559 3.205 2.840 3.752 4.367 4.604 2.638 0.0147122 family with sequence similarity 126, member A CLDN10 2.296 2.627 2.296 4.983 3.697 3.043 2.639 0.0392479 claudin 10 ASXL1 5.837 5.419 5.861 6.819 7.011 7.363 2.640 0.0078450 additional sex combs like 1 (Drosophila) MMAA 3.412 4.371 3.206 5.062 4.607 5.745 2.640 0.0282410 methylmalonic aciduria (cobalamin deficiency) cbiA type TGDS 2.671 2.836 3.616 4.637 4.239 4.158 2.644 0.0190553 TDP-glucose 4,6-dehydratase PAGI 4.126 3.571 3.886 6.029 5.290 4.368 2.647 0.0394674 phosphoprotein associated with glycosphingolipid microdomains 1 KIAA1919 3.706 5.049 4.296 5.821 5.776 5.112 2.650 0.0454758 KIAA1919 HSPG2 7.286 7.580 8.159 8.692 8.961 9.602 2.651 0.0185733 heparan sulfate proteoglycan 2 C4orf32 3.706 4.032 2.916 4.983 4.512 5.439 2.651 0.0235533 chromosome 4 open reading frame 32 SNHG10 3.810 3.173 3.173 4.580 4.227 5.571 2.652 0.0285602 small nucleolar RNA host gene 10 (non-protein coding) VAC14 3.117 3.410 4.315 4.838 4.821 4.665 2.659 0.0353492 Vac14 homolog (S. cerevisiae) NAA15 4.964 5.510 5.642 5.968 7.058 6.922 2.661 0.0307299 N(alpha)-acetyltransferase 15, NatA auxiliary subunit TMEM213 6.680 5.897 5.880 7.898 7.294 7.370 2.664 0.0157897 transmembrane protein 213 MCOLN2 4.991 5.253 5.988 6.746 6.407 6.752 2.669 0.0225725 mucolipin 2 PPP2R5B 9.641 8.691 8.932 10.134 10.349 10.596 2.670 0.0193607 protein phosphatase 2, regulatory subunit B′, beta LIX1L −0.026 2.108 1.734 3.335 2.636 3.152 2.672 0.0341343 Lix1 homolog (mouse)-like HLA-B 13.780 14.160 14.258 15.724 15.548 15.205 2.686 0.0059294 major histocompatibility complex, class I, B UGP2 5.545 5.777 4.719 6.422 6.747 7.204 2.688 0.0192302 UDP-glucose pyrophosphorylase 2 DLL4 0.974 1.050 0.974 2.108 2.402 3.304 2.690 0.0109877 delta-like 4 (Drosophila) LSM11 0.974 1.050 1.050 2.404 3.022 2.404 2.694 0.0036009 LSM11, U7 small nuclear RNA associated COL2A1 0.974 0.974 1.264 2.848 2.402 2.404 2.694 0.0036608 collagen, type II, alpha 1 LOC1001339 0.974 0.974 0.974 2.404 2.848 1.819 2.694 0.0130414 No description 20 ZNF484 0.974 1.328 0.974 2.848 1.692 2.404 2.694 0.0281781 zinc finger protein 484 psiTPTE22 0.974 1.050 2.432 3.772 3.022 2.404 2.694 0.0380821 No description CCDC3 0.974 2.546 1.692 2.404 3.887 3.922 2.694 0.0392371 coiled-coil domain containing 3 TOPORS 4.946 5.608 4.047 6.376 6.096 6.618 2.695 0.0254712 topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase SLC44A1 7.517 8.577 7.912 10.007 9.246 9.108 2.696 0.0211228 solute carrier family 44, member 1 NCBP1 5.975 4.813 4.725 6.155 6.815 6.672 2.696 0.0300798 nuclear cap binding protein subunit 1,80 kDa SNX5 8.871 7.731 8.382 9.813 9.973 9.463 2.696 0.0171773 sorting nexin 5 HIVEP3 6.813 7.903 8.321 8.546 9.250 9.752 2.697 0.0374682 human immunodeficiency virus type I enhancer binding protein 3 DNAJC8 8.362 8.208 8.860 9.767 9.852 9.797 2.703 0.0074129 DnaJ (Hsp40) homolog, subfamily C, member 8 ZFP41 4.290 4.179 5.210 6.404 5.760 5.616 2.708 0.0248649 zinc finger protein 41 homolog (mouse) MLXIPL 3.616 4.824 5.281 6.718 5.827 5.744 2.709 0.0383139 MLX interacting protein-like NOLC1 5.513 5.585 5.436 6.339 7.002 7.023 2.709 0.0108243 nucleolar and coiled-body phosphoprotein 1 FRG1 5.086 5.678 5.514 7.164 6.953 6.056 2.710 0.0262180 FSHD region gene 1 DBF4B 9.101 8.539 8.795 10.346 10.074 10.235 2.713 0.0047337 DBF4 homolog B (S. cerevisiae) C2orf60 4.377 4.991 5.256 6.562 6.433 5.828 2.716 0.0163384 chromosome 2 open reading frame 60 POLL 6.787 6.104 6.407 7.852 7.738 7.949 2.722 0.0059616 polymerase (DNA directed), lambda AARSD1 5.435 4.514 4.585 6.511 6.343 5.959 2.722 0.0146608 alanyl-tRNA synthetase domain containing 1 CAPZB 11.499 11.432 11.624 13.262 12.946 12.317 2.726 0.0138780 capping protein (actin filament) muscle Z-line, beta LOC150381 6.630 6.217 7.227 8.371 8.233 7.669 2.735 0.0181681 No description C10orf90 3.059 2.948 2.758 4.512 4.144 4.422 2.737 0.0029831 chromosome 10 open reading frame 90 MAP4K4 8.078 8.583 8.440 9.942 9.801 9.893 2.738 0.0028005 mitogen-activated protein kinase kinase kinase kinase 4 DCP1B 1.974 4.222 3.712 5.167 5.556 4.378 2.741 0.0464674 DCP1 decapping enzyme homolog B (S. cerevisiae) SFXN1 4.350 5.214 5.258 6.713 6.081 6.226 2.741 0.0170668 sideroflexin 1 BAZ1B 6.133 7.137 7.699 8.550 8.890 8.592 2.742 0.0160691 bromodomain adjacent to zinc finger domain, 1B DGKE 6.600 6.520 7.100 8.056 8.131 8.013 2.742 0.0064697 diacylglycerol kinase, epsilon 64 kDa PDGFA 4.125 5.890 4.979 6.120 6.434 7.315 2.742 0.0355188 platelet-derived growth factor alpha polypeptide LOC401127 3.892 4.192 4.375 5.989 5.648 5.309 2.743 0.0063822 No description MRPL32 8.752 8.928 8.479 10.190 10.384 10.205 2.744 0.0022540 mitochondrial ribosomal protein L32 DYNLL1 11.047 10.410 11.446 12.504 12.137 12.840 2.746 0.0134981 dynein, light chain, LC8-type 1 GPX3 3.434 5.312 5.544 7.001 6.717 5.756 2.746 0.0470952 glutathione peroxidase 3 (plasma) SDF4 8.896 9.905 9.449 11.363 10.939 10.263 2.746 0.0237299 stromal cell derived factor 4 ZNF692 8.405 7.000 8.488 9.769 9.636 9.947 2.749 0.0136992 zinc finger protein 692 CONC 5.378 5.289 5.277 6.924 6.749 6.170 2.752 0.0102709 cyclin 0 GDAP1 3.908 4.014 3.616 5.475 5.475 4.570 2.752 0.0176332 ganglioside-induced differentiation-associated protein 1 INPP5K 5.140 6.325 5.845 7.520 7.305 6.996 2.752 0.0150998 inositol polyphosphate-5-phosphatase K SIDT2 8.076 6.671 7.178 8.664 8.640 8.637 2.756 0.0273400 SID1 transmembrane family, member 2 SMG6 5.967 7.509 8.503 9.158 8.977 8.834 2.766 0.0496048 Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) ADORA2A 4.492 6.270 5.547 6.986 6.447 7.742 2.773 0.0377352 adenosine A2a receptor RUNDC2C 3.296 3.374 3.913 4.772 5.427 4.820 2.781 0.0093530 RUN domain containing 2C GNG4 2.296 3.934 4.241 5.410 5.443 4.701 2.782 0.0342348 guanine nucleotide binding protein (G protein), gamma 4 MNAT1 6.674 6.863 7.537 9.014 8.747 8.064 2.783 0.0132502 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) CD58 4.710 4.339 4.351 6.191 5.624 5.896 2.791 0.0053231 CD58 molecule ATP5J2 6.210 5.183 7.063 7.618 8.544 7.279 2.791 0.0379186 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 C15orf24 6.140 6.611 5.373 7.640 7.622 6.911 2.793 0.0298005 chromosome 15 open reading frame 24 FGL2 4.126 2.861 3.642 5.223 5.125 4.978 2.795 0.0130844 fibrinogen-like 2 METTL2A 7.173 5.723 6.084 7.794 7.571 7.348 2.803 0.0431857 methyltransferase like 2A TCEA2 7.424 6.190 8.087 8.912 8.919 8.582 2.805 0.0320599 transcription elongation factor A (Sil), 2 TBC1D10A 4.544 3.928 3.723 5.595 5.484 5.214 2.811 0.0113784 TBC1 domain family, member 10A PMS2 5.197 4.944 5.944 6.694 6.797 6.438 2.817 0.0193031 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) NEKS 4.872 4.470 5.613 6.472 5.966 6.842 2.821 0.0220698 NIMA (never in mitosis gene a)- related kinase 9 SMCR8 6.199 7.656 7.715 9.211 8.553 8.609 2.821 0.0263553 Smith-Magenis syndrome chromosome region, candidate 8 RNASEH2C 3.470 3.844 4.873 5.967 5.341 5.171 2.823 0.0308757 ribonuclease H2, subunit C MRTO4 6.711 7.659 8.709 9.157 9.990 8.857 2.824 0.0403546 mRNA turnover 4 homolog (S. cerevisiae) BTRC 3.539 4.921 5.160 5.820 6.420 6.574 2.826 0.0215265 beta-transducin repeat containing VCAN 1.559 1.759 1.559 4.705 2.454 3.059 2.828 0.0315718 versican ADI1 5.049 4.927 5.119 6.961 6.376 6.549 2.829 0.0028726 acireductone dioxygenase 1 UIMC1 5.309 5.317 4.764 6.437 6.536 6.820 2.834 0.0054305 ubiquitin interaction motif containing 1 ITCH 5.186 4.795 5.093 6.547 6.694 6.545 2.844 0.0016493 itchy E3 ubiquitin protein ligase homolog (mouse) ABCD1 4.492 5.534 6.395 7.168 6.566 7.042 2.845 0.0436869 ATP-binding cassette, sub-family D (ALD), member 1 ACOX3 6.927 6.606 7.738 9.178 8.898 8.116 2.848 0.0173323 acyl-CoA oxidase 3, pristanoyl DCLRE1C 5.254 5.009 6.172 7.683 7.577 6.439 2.849 0.0187951 DNA cross-link repair 1C C10orf35 6.858 6.089 7.754 8.962 8.851 7.601 2.851 0.0436262 chromosome 10 open reading frame 35 ZNF507 4.374 4.418 4.094 5.930 5.691 5.744 2.852 0.0020814 zinc finger protein 507 VPS25 8.394 8.969 8.806 11.110 10.319 9.535 2.854 0.0210345 vacuolar protein sorting 25 homolog (S. cerevisiae) ALOX12P2 2.296 3.376 2.875 5.154 4.042 3.809 2.854 0.0317091 arachidonate 12-lipoxygenase pseudogene 2 MIDI IPI 6.296 6.692 6.115 7.809 7.648 7.828 2.854 0.0048987 MIDI interacting protein 1 (gastrulation specific G12 homolog (zebrafish)) SLC25A3 7.112 6.977 6.783 8.533 8.628 7.680 2.859 0.0168665 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 ZNF350 3.090 2.075 1.610 3.848 3.187 3.591 2.861 0.0431090 zinc finger protein 350 RINT1 5.720 6.093 4.825 7.272 7.237 6.471 2.861 0.0261903 RAD50 interactor 1 MX2 0.974 1.643 2.098 3.160 3.022 3.304 2.862 0.0097360 myxovirus (influenza virus) resistance 2 (mouse) RASD2 3.593 2.625 2.819 4.917 4.222 4.338 2.867 0.0150698 RASD family, member 2 CENPM 2.519 3.187 4.390 4.952 4.706 4.705 2.867 0.0422095 centromere protein M JAM2 0.974 1.328 0.974 2.848 2.402 2.777 2.868 0.0029263 junctional adhesion molecule 2 VWDE 2.296 2.296 2.327 4.486 3.817 3.043 2.868 0.0200652 von Willebrand factor D and EGF domains MUT 2.296 2.838 3.809 4.537 3.817 4.740 2.868 0.0409210 methylmalonyl CoA mutase UBFD1 5.967 5.703 6.087 7.670 7.465 7.226 2.874 0.0030315 ubiquitin family domain containing 1 PPAPDC2 3.616 5.395 4.647 6.650 6.170 5.603 2.874 0.0349401 phosphatidic acid phosphatase type 2 domain containing 2 C2orf15 7.713 7.332 7.597 9.236 9.150 8.832 2.874 0.0029724 chromosome 2 open reading frame 15 PQLC1 8.469 9.177 9.887 10.705 10.647 10.863 2.883 0.0161466 PQ loop repeat containing 1 ZNF397OS 5.167 4.844 4.572 6.697 6.455 6.068 2.888 0.0058757 No description LOC283314 5.497 4.846 6.423 7.742 7.664 6.376 2.888 0.0340913 No description NASP 8.454 7.487 7.984 9.498 9.515 9.719 2.891 0.0068596 nuclear autoantigenic sperm protein (histone-binding) GPATCH3 5.954 5.667 6.293 7.842 7.487 6.999 2.894 0.0107183 G patch domain containing 3 DNM1L 7.239 7.328 6.939 8.775 8.801 8.749 2.900 0.0013753 dynamin 1-like RPL12 14.890 13.395 14.196 15.217 15.932 15.733 2.903 0.0279363 ribosomal protein L12 HPS6 5.931 5.942 4.906 7.480 7.358 6.616 2.903 0.0182786 Hermansky-Pudlak syndrome 6 C11orf57 4.854 5.465 4.474 6.392 6.396 6.063 2.903 0.0149854 chromosome 11 open reading frame 57 C4orf52 3.220 2.860 4.223 4.572 4.759 4.842 2.907 0.0319823 chromosome 4 open reading frame 52 TSHZ3 2.944 3.358 2.602 4.486 4.683 4.296 2.912 0.0060867 teashirt zinc finger homeobox 3 NPTN 8.294 8.274 8.029 9.665 9.610 9.839 2.917 0.0016385 neuroplastin SHC1 5.064 6.148 5.487 7.407 7.032 6.797 2.918 0.0137843 SHC (Src homology 2 domain containing) transforming protein 1 TEX264 7.463 7.714 9.445 10.990 10.154 8.992 2.919 0.0494628 testis expressed 264 SLC39A13 7.894 8.786 9.234 10.333 10.575 10.331 2.922 0.0095196 solute carrier family 39 (zinc transporter), member 13 MUC16 6.136 8.166 8.865 9.716 9.593 9.900 2.927 0.0340046 mucin 16, cell surface associated SLC10A7 4.126 2.686 3.532 5.335 4.861 5.083 2.931 0.0152387 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 OR7E91P 2.878 2.108 2.348 3.659 4.406 4.235 2.931 0.0078089 olfactory receptor, family 7, subfamily E, member 91 pseudogene LOC400043 4.899 6.454 7.518 7.940 8.253 8.007 2.933 0.0430192 No description ROBO4 2.747 2.649 2.013 5.441 3.712 3.565 2.934 0.0286961 roundabout homolog 4, magic roundabout (Drosophila) PCBD1 5.516 4.164 5.050 6.781 6.660 5.719 2.938 0.0324935 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha DHX8 7.154 7.328 8.181 9.503 9.527 8.710 2.939 0.0123269 DEAH (Asp-Glu-Ala-His) box polypeptide 8 PPM1H 3.865 5.074 4.098 6.807 5.655 5.420 2.941 0.0289210 protein phosphatase, Mg2+/Mn2+ dependent, 1H C10orf118 5.258 5.123 5.414 6.972 6.850 6.603 2.945 0.0020491 chromosome 10 open reading frame 118 CD74 7.507 6.933 6.556 8.679 9.070 7.482 2.954 0.0429194 CD74 molecule, major histocompatibility complex, class II invariant chain LDLR 11.958 11.786 13.234 13.521 13.489 13.567 2.956 0.0490798 low density lipoprotein receptor COL6A2 9.560 11.541 10.902 11.950 12.471 12.964 2.966 0.0281673 collagen, type VI, alpha 2 KLHL15 5.191 3.745 4.116 5.685 5.430 6.005 2.968 0.0341174 kelch-like 15 (Drosophila) GLG1 8.675 8.379 8.927 10.628 10.244 9.866 2.969 0.0062847 golgi glycoprotein 1 HSD11B2 5.410 4.098 4.428 5.313 6.194 6.980 2.970 0.0442855 hydroxysteroid (11-beta) dehydrogenase 2 METTL5 5.237 4.799 3.874 6.370 6.439 5.720 2.972 0.0214551 methyltransferase like 5 UBA5 6.945 6.903 6.690 8.476 8.913 7.621 2.974 0.0165318 ubiquitin-like modifier activating enzyme 5 KIAA0196 1.974 2.162 2.649 4.222 3.196 3.744 2.975 0.0152226 KIAA0196 UBLCP1 4.687 3.747 3.257 5.930 4.830 5.364 2.975 0.0333338 ubiquitin-like domain containing CTD phosphatase 1 FCHO2 3.616 3.744 4.150 5.317 4.547 6.034 2.975 0.0253338 FCH domain only 2 PRSS36 4.448 3.426 3.324 6.025 5.342 4.801 2.983 0.0201850 protease, serine, 36 PDE7B 1.974 2.953 2.377 3.704 4.098 3.954 2.984 0.0105457 phosphodiesterase 7B SSBP3 4.003 3.533 3.927 5.112 5.345 5.887 2.987 0.0055741 single stranded DNA binding protein 3 PKP2 4.231 4.091 5.803 6.667 6.463 5.671 2.991 0.0412187 plakophilin 2 HEATR1 5.362 6.614 5.624 7.011 7.709 7.207 2.996 0.0236493 HEAT repeat containing 1 HSPB7 0.974 1.264 1.643 3.469 2.848 1.819 2.998 0.0371213 heat shock 27 kDa protein family, member 7 (cardiovascular) KLHL7 3.364 4.072 3.776 4.950 5.429 5.399 3.002 0.0067145 kelch-like 7 (Drosophila) TIMM17B 8.253 7.073 7.757 9.420 9.345 8.900 3.005 0.0145280 translocase of inner mitochondrial membrane 17 homolog B (yeast) FGFBP1 7.571 9.276 9.494 9.672 10.736 11.084 3.012 0.0443607 fibroblast growth factor binding protein 1 H LA-DOB 3.247 1.974 1.974 4.833 4.098 3.565 3.013 0.0206823 major histocompatibility complex, class II, DO beta SENP1 4.350 5.560 4.651 6.539 6.328 5.942 3.015 0.0214743 SUMO1/sentrin specific peptidase 1 EFNA1 10.382 9.552 9.204 10.991 11.180 11.144 3.016 0.0176439 ephrin-A1 FAM115A 8.006 6.881 7.880 9.498 9.472 9.249 3.016 0.0069071 family with sequence similarity 115, member A TIPRL 6.601 6.781 6.837 8.658 8.374 8.185 3.016 0.0016838 TIP41, TOR signaling pathway regulator-like (S. cerevisiae) LPCAT1 5.718 6.515 7.305 8.278 7.702 8.110 3.021 0.0256646 lysophosphatidylcholine acyltransferase 1 CTU2 6.021 6.238 7.360 7.719 8.016 7.833 3.022 0.0308864 cytosolic thiouridylase subunit 2 homolog (S. pombe) MPPE1 5.317 6.047 6.180 7.644 8.193 6.868 3.025 0.0149962 metallophosphoesterase 1 NT5DC3 6.867 6.787 6.342 7.940 8.196 9.934 3.027 0.0179655 5′-nucleotidase domain containing 3 BTN2A2 7.104 6.234 5.558 8.605 7.156 7.884 3.027 0.0372970 butyrophilin, subfamily 2, member A2 ABCC13 4.054 2.752 3.262 4.507 5.797 4.354 3.035 0.0387598 ATP-binding cassette, sub-family C (CFTR/MRP), member 13,pseudogene AIP 2.296 3.648 3.468 4.921 5.252 4.445 3.038 0.0156285 aryl hydrocarbon receptor interacting protein ZNF331 4.890 4.148 4.492 6.149 5.752 6.467 3.039 0.0072617 zinc finger protein 331 TUBB2B 6.457 5.202 3.693 6.807 6.797 7.081 3.042 0.0482425 tubulin, beta 2B TMEM106A 4.363 4.458 5.062 6.067 6.174 6.033 3.051 0.0058649 transmembrane protein 106A ZEB1 2.782 3.491 2.804 5.101 4.276 4.444 3.052 0.0104282 zinc finger E-box binding homeobox 1 FAM110A 6.091 6.850 6.195 7.703 7.825 8.008 3.057 0.0078619 family with sequence similarity 110, member A CMTM1 0.974 1.691 2.134 3.746 2.402 3.304 3.057 0.0273185 CKLF-like MARVEL transmembrane domain containing 1 IFH 6 5.178 7.253 6.909 8.048 7.807 8.866 3.058 0.0357245 interferon, gamma-inducible protein 16 SFRS8 7.610 7.890 9.000 9.624 9.223 9.845 3.061 0.0302387 No description ZFAND2B 6.882 6.773 6.549 8.164 8.218 8.574 3.064 0.0023576 zinc finger, AN1-type domain 2B KTELC1 4.408 5.239 5.580 7.196 6.985 5.764 3.066 0.0317406 No description C17orf63 8.367 7.481 7.967 9.537 9.600 9.590 3.079 0.0047675 chromosome 17 open reading frame 63 INHA 4.215 2.860 1.974 5.556 4.353 4.486 3.088 0.0409102 inhibin, alpha GRK4 1.559 2.110 1.973 3.032 3.600 4.647 3.089 0.0128542 G protein-coupled receptor kinase 4 SH3PXD2A 6.668 5.328 5.798 7.574 6.957 7.904 3.092 0.0230537 SH3 and PX domains 2A NEDD4 3.412 4.066 4.389 5.694 5.671 5.943 3.092 0.0043331 neural precursor cell expressed, developmentally down- regulated 4 C17orf77 1.974 2.013 2.086 3.643 3.583 4.969 3.096 0.0074236 chromosome 17 open reading frame 77 ATP6V1E1 5.578 6.054 7.180 7.687 8.454 7.316 3.100 0.0357836 ATPase, H+ transporting, lysosomal 31 kDa, V1 subunit E1 UCA1 2.559 2.861 2.710 4.727 4.344 3.173 3.104 0.0345449 urothelial cancer associated 1 (non-protein coding) MRVH 0.974 0.974 0.974 2.610 3.324 1.819 3.108 0.0159808 murine retrovirus integration site 1 homolog GYS1 8.691 7.683 8.948 10.572 10.584 9.027 3.108 0.0386922 glycogen synthase 1 (muscle) LRRC1 4.512 5.553 5.955 7.591 6.866 6.964 3.109 0.0139908 leucine rich repeat containing 1 UTP6 6.770 6.437 5.825 7.447 8.082 8.539 3.127 0.0129793 UTP6, small subunit (SSU) processome component, homolog (yeast) HOXC11 −0.026 1.688 2.038 2.836 3.649 3.335 3.131 0.0199271 homeobox C11 IMPA2 6.404 7.239 6.869 9.629 8.517 7.563 3.135 0.0308135 inositol(myo)-1 (or 4)-monophosphatase 2 RAB4A 7.334 6.706 6.473 8.122 8.414 8.566 3.137 0.0085649 RAB4A, member RAS oncogene family BTG3 4.360 5.382 5.125 7.035 6.442 6.421 3.144 0.0096508 BTG family, member 3 NOC4L 7.614 8.091 9.123 9.746 10.003 9.320 3.148 0.0328941 nucleolar complex associated 4 homolog (S. cerevisiae) SESN1 6.950 6.152 5.616 7.773 7.808 8.400 3.152 0.0121036 sestrin 1 LRCH1 8.295 8.256 9.254 9.937 9.953 10.459 3.154 0.0141919 leucine-rich repeats and calponin homology (CH) domain containing 1 FUT6 0.974 1.050 1.050 3.836 2.712 2.404 3.165 0.0080806 fucosyltransferase 6 (alpha (1.3) fucosyltransferase) APOL1 1.559 2.747 2.848 4.512 4.144 3.859 3.168 0.0123592 apolipoprotein L, 1 MAD2L1BP 5.412 4.099 5.236 7.574 5.765 6.317 3.171 0.0416616 MAD2L1 binding protein PCYOX1 5.028 5.516 5.245 7.258 6.695 6.695 3.174 0.0042402 prenylcysteine oxidase 1 ITPRIP 3.272 3.542 3.044 4.759 5.171 4.939 3.175 0.0024313 inositol 1,4,5-triphosphate receptor interacting protein PLB1 1.974 3.220 3.334 4.899 4.892 3.704 3.188 0.0290652 phospholipase B1 SERPINB6 8.545 9.062 9.855 11.350 10.816 10.218 3.190 0.0207437 serpin peptidase inhibitor. clade B (ovalbumin), member 6 C10orf54 3.272 3.440 4.486 5.826 5.114 5.035 3.191 0.0185050 chromosome 10 open reading frame 54 TM2D2 4.969 6.237 7.339 8.340 7.879 7.912 3.194 0.0295180 TM2 domain containing 2 FGFRL1 6.932 7.107 7.836 8.268 9.516 8.999 3.204 0.0167959 fibroblast growth factor receptor-like 1 NRN1 0.974 2.404 1.643 3.324 2.848 3.758 3.208 0.0197736 neuritin 1 FBXO10 3.272 4.741 6.061 6.391 6.427 6.580 3.217 0.0489325 F-box protein 10 PATL1 8.650 8.495 8.315 10.182 9.312 10.419 3.219 0.0137951 protein associated with topoisomerase II homolog 1 (yeast) SLC29A1 8.460 7.869 8.251 10.083 9.940 9.797 3.223 0.0020384 solute carrier family 29 (nucleoside transporters), member 1 NHEDC2 5.514 5.027 5.263 6.910 7.036 6.951 3.224 0.0014758 Na+/H+ exchanger domain containing 2 C8orf46 1.559 2.968 4.160 4.597 5.153 4.658 3.227 0.0348127 chromosome 8 open reading frame 46 PITPNB 7.295 7.144 8.187 8.986 8.938 9.615 3.228 0.0122448 phosphatidylinositol transfer protein, beta IL17RA 5.132 5.166 5.158 6.850 7.038 6.502 3.232 0.0018880 interleukin 17 receptor A TSEN54 6.013 6.821 6.815 8.343 8.514 7.821 3.234 0.0084114 tRNA splicing endonuclease 54 homolog (S. cerevisiae) ZBTB7B 8.482 8.838 9.044 10.532 10.567 10.414 3.236 0.0017659 zinc finger and BTB domain containing 7B PHB2 11.919 11.411 13.211 13.613 13.944 13.207 3.237 0.0477030 prohibitin 2 AIDA 4.870 6.197 6.017 7.893 7.235 7.165 3.241 0.0150230 axin interactor, dorsalization associated UBE2Q1 5.623 6.558 6.267 7.964 8.234 7.331 3.242 0.0103223 ubiquitin-conjugating enzyme E2Q family member 1 MAP3K7IP3 6.554 7.194 6.413 8.652 8.325 8.111 3.246 0.0060652 No description HSPB2 2.519 1.759 1.759 2.650 3.459 4.755 3.251 0.0423070 heat shock 27 kDa protein 2 PRKDC 8.236 8.956 10.039 10.658 11.033 10.219 3.252 0.0339048 protein kinase, DNA-activated, catalytic polypeptide LDB2 2.519 2.650 2.037 4.353 4.013 4.144 3.257 0.0023185 LIM domain binding 2 SPSB3 10.098 9.233 7.344 10.997 10.658 10.939 3.263 0.0360890 splA/ryanodine receptor domain and SOCS box containing 3 C6orf120 7.217 6.376 7.602 8.272 9.309 8.304 3.265 0.0238603 chromosome 6 open reading frame 120 FXYD5 6.120 8.704 7.757 9.615 9.465 8.863 3.268 0.0452525 FXYD domain containing ion transport regulator 5 HTR3B 6.505 5.506 6.652 8.361 8.158 7.541 3.268 0.0108457 5-hydroxytryptamine (serotonin) receptor 3B REM1 −0.026 1.913 2.263 3.335 3.176 3.974 3.275 0.0226270 RAS (RAD and GEM)-like GTP-binding 1 RAB4B 2.878 3.772 2.348 5.240 4.952 4.062 3.280 0.0200123 RAB4B, member RAS oncogene family S100A8 0.974 3.747 3.796 5.513 5.074 5.236 3.286 0.0248964 S100 calcium binding protein A8 PRDX3 10.007 8.355 8.975 10.948 10.692 10.150 3.287 0.0343292 peroxiredoxin 3 MRPS6 3.793 4.280 4.900 6.493 5.999 5.614 3.291 0.0113008 mitochondrial ribosomal protein S6 MAST3 4.142 4.786 4.623 7.192 5.975 5.865 3.303 0.0120553 microtubule associated serine/threonine kinase 3 SHROOM2 4.631 4.968 4.486 7.156 6.357 6.034 3.308 0.0067437 shroom family member 2 FBXL8 2.878 4.983 5.512 6.715 6.976 5.797 3.322 0.0384628 F-box and leucine-rich repeat protein 8 PIGP 6.184 5.644 6.335 8.154 7.556 7.378 3.326 0.0077022 phosphatidylinositol glycan anchor biosynthesis, class P PDE4C 3.831 4.140 4.456 5.875 5.661 6.114 3.329 0.0028404 phosphodiesterase 4C, cAMP-specific PECR 3.188 1.913 3.664 5.810 4.780 3.649 3.332 0.0456109 peroxisomal trans-2-enoyl-CoA reductase ATP10D 2.559 3.642 2.610 4.991 3.914 5.379 3.333 0.0185157 ATPase, class V, type 10D SULT1A4 6.790 7.681 8.280 8.956 9.419 9.841 3.335 0.0143738 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 FAM43A 7.187 6.011 7.002 8.928 8.347 8.180 3.344 0.0115986 family with sequence similarity 43, member A PKP4 9.896 8.754 10.477 11.867 11.640 10.745 3.349 0.0284183 plakophilin 4 RNF26 6.520 7.445 8.156 9.394 9.189 8.481 3.349 0.0249908 ring finger protein 26 PAK6 3.220 4.759 4.922 6.798 6.505 4.899 3.353 0.0487943 p21 protein (Cdc42/Rac)-activated kinase 6 FGFR2 7.026 6.137 6.539 8.094 8.286 8.718 3.356 0.0050468 fibroblast growth factor receptor 2 ACBD6 2.519 3.475 2.217 5.225 4.765 3.591 3.365 0.0246493 acyl-CoA binding domain containing 6 C8orf37 4.851 4.165 4.512 7.826 6.264 5.027 3.370 0.0451427 chromosome 8 open reading frame 37 RBM27 5.246 6.217 5.645 7.628 7.669 7.000 3.371 0.0081765 RNA binding motif protein 27 FAM134B 6.116 4.396 4.374 7.313 6.672 6.128 3.372 0.0334551 family with sequence similarity 134, member B ABLIM2 2.296 2.749 3.061 5.759 4.503 3.809 3.374 0.0166746 actin binding LIM protein family, member 2 ZC3H7B 6.018 6.290 7.441 8.081 8.045 7.878 3.376 0.0259133 zinc finger CCCH-type containing 7B KREMEN1 4.102 5.439 5.626 7.160 7.382 6.953 3.379 0.0082456 kringle containing transmembrane protein 1 MAPI A 0.974 1.264 1.264 3.022 2.402 3.922 3.382 0.0088158 microtubule-associated protein 1A GPATCH2 6.962 5.987 6.053 7.745 8.530 8.297 3.384 0.0076470 G patch domain containing 2 ACTR5 5.514 6.429 7.367 8.188 8.194 8.000 3.385 0.0218028 ARP5 actin-related protein 5 homolog (yeast) KLHL26 2.296 2.419 2.652 5.084 4.042 4.178 3.385 0.0041504 kelch-like 26 (Drosophila) TMEM100 −0.026 −0.026 0.121 1.734 1.169 2.108 3.386 0.0054904 transmembrane protein 100 XPO1 8.763 8.744 7.679 9.776 9.829 10.523 3.388 0.0145817 exportin 1 (CRM1 homolog, yeast) ANKRD49 3.059 4.015 2.703 4.464 5.392 5.444 3.390 0.0140483 ankyrin repeat domain 49 BRF1 7.292 6.701 7.191 8.645 8.953 8.982 3.391 0.0021704 BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) ST6GALNAC 3.090 2.404 3.032 4.236 4.853 4.630 3.394 0.0046692 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N- 5 acetylgalactosaminide al pha-2,6-sialyltransferase 5 METTL11A 7.112 7.209 6.843 9.180 8.769 8.613 3.409 0.0019440 methyltransferase like 11A PRPSAP2 6.683 7.001 7.327 9.535 8.455 8.539 3.415 0.0081128 phosphoribosyl pyrophosphate synthetase-associated protein 2 IKZF2 3.999 4.520 3.366 6.073 5.774 5.164 3.422 0.0126761 IKAROS family zinc finger 2 (Helios) WWOX 3.220 3.644 4.860 5.556 5.419 5.070 3.423 0.0343645 WW domain containing oxidoreductase WDR27 3.728 3.540 4.420 6.195 5.186 5.849 3.424 0.0082187 WD repeat domain 27 HUNK 1.974 2.161 2.747 3.868 3.937 4.098 3.426 0.0038849 hormonally up-regulated Neu-associated kinase MTHFD2L 3.831 4.686 5.124 5.543 6.464 6.993 3.428 0.0205226 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like USH1G 3.616 4.327 4.795 5.735 6.106 6.272 3.432 0.0081573 Usher syndrome 1 G (autosomal recessive) ADNP 7.434 6.206 5.834 8.089 7.690 7.988 3.438 0.0330107 activity-dependent neuroprotector homeobox UPF3B 6.204 5.516 5.538 7.421 7.301 7.510 3.446 0.0037598 UPF3 regulator of nonsense transcripts homolog B (yeast) SPARC 4.017 4.282 3.967 6.549 5.424 5.805 3.452 0.0056293 secreted protein, acidic, cysteine-rich (osteonectin) ARPC3 3.059 3.246 4.841 5.964 5.898 4.851 3.462 0.0266285 actin related protein 2/3 complex, subunit 3, 21 kDa MLX 7.736 8.003 8.354 10.170 9.768 9.528 3.463 0.0033615 MAX-like protein X DLAT 4.795 6.653 5.913 7.866 7.706 6.755 3.464 0.0359401 dihydrolipoamide S-acetyltransferase KCNMB1 1.974 2.860 3.583 3.678 4.652 6.008 3.465 0.0361082 potassium large conductance calcium-activated channel, subfamily M. beta member 1 ZNF425 6.112 6.305 6.513 8.280 8.112 7.958 3.499 0.0011013 zinc finger protein 425 USP40 6.107 7.080 7.217 9.028 8.676 7.949 3.508 0.0144167 ubiquitin specific peptidase 40 COMT 3.927 5.087 5.564 6.914 6.899 6.135 3.511 0.0188565 catechol-O-methyltransferase C6orf211 4.353 4.051 3.459 6.852 5.273 5.525 3.514 0.0147713 chromosome 6 open reading frame 211 ANGPTL2 0.974 2.247 1.738 4.062 2.848 3.469 3.517 0.0152118 angiopoietin-like 2 MGC12982 1.559 1.759 3.186 3.851 3.374 4.007 3.518 0.0289739 No description ENDOG 6.404 6.246 7.088 8.904 8.375 6.976 3.522 0.0467429 endonuclease G ZNF844 4.512 2.519 3.032 4.851 4.765 5.027 3.527 0.0402594 zinc finger protein 844 RNH1 9.816 10.089 10.527 12.232 12.198 11.640 3.541 0.0032909 ribonuclease/angiogenin inhibitor 1 DCTN2 11.097 10.294 9.336 12.493 12.119 11.613 3.544 0.0188196 dynactin 2 (p50) RCN3 0.974 2.108 1.643 5.020 2.402 3.469 3.546 0.0321627 reticulocalbin 3, EF-hand calcium binding domain AKR1E2 0.974 1.050 1.050 2.848 2.848 2.878 3.551 0.0002379 aldo-keto reductase family 1, member E2 LCLAT1 5.138 6.522 5.792 8.324 7.622 7.226 3.557 0.0128434 lysocardiolipin acyltransferase 1 ITGB5 9.578 10.950 11.925 12.784 12.806 11.890 3.565 0.0485610 integrin, beta 5 KIAA1324L 3.412 3.511 3.366 5.112 5.345 5.288 3.566 0.0004774 KIAA1324-like LOC1001709 2.878 1.738 3.089 4.379 4.062 4.926 3.573 0.0118419 No description 39 GFER 5.749 5.899 6.296 8.334 7.737 7.483 3.574 0.0038373 growth factor, augmenter of liver regeneration LOC440944 6.453 5.681 6.461 7.713 7.666 8.299 3.574 0.0073914 No description OSTF1 7.042 7.883 7.591 9.975 9.440 8.824 3.602 0.0079586 osteoclast stimulating factor 1 KCNH3 0.974 2.072 2.348 3.922 3.478 3.922 3.605 0.0081466 potassium voltage-gated channel, subfamily H (eag- related), member 3 FOXO1 6.631 7.341 7.147 9.039 8.487 9.046 3.619 0.0037038 forkhead box O1 CDKN2A 4.851 5.021 4.512 6.708 7.024 5.691 3.624 0.0135480 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) EYA2 7.471 6.541 7.835 9.539 9.330 9.017 3.628 0.0060438 eyes absent homolog 2 (Drosophila) TUBE1 5.827 5.186 5.217 7.327 7.687 5.895 3.631 0.0354367 tubulin, epsilon 1 POU3F1 3.090 2.075 2.674 4.144 4.382 4.952 3.636 0.0066086 POU class 3 homeobox 1 LZTS1 3.220 2.377 3.263 4.344 4.759 5.126 3.638 0.0076147 leucine zipper, putative tumor suppressor 1 RBM19 6.311 6.277 8.039 8.576 8.404 8.141 3.640 0.0417544 RNA binding motif protein 19 CHST9 2.944 2.327 3.218 4.823 4.601 4.809 3.644 0.0028511 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 KDM5C 8.291 7.035 7.193 9.334 9.148 8.901 3.644 0.0142111 lysine (K)-specific demethylase 5C CSF3R 5.772 5.660 7.397 8.642 7.835 7.526 3.645 0.0324328 colony stimulating factor 3 receptor (granulocyte) HAX1 9.307 8.672 9.111 10.979 11.499 10.489 3.651 0.0043438 HCLS1 associated protein X-1 CNBP 8.062 7.358 6.700 9.229 8.739 9.229 3.657 0.0129447 CCHC-type zinc finger, nucleic acid binding protein VHL 7.708 9.118 8.280 10.235 10.152 9.614 3.658 0.0167529 von Hippel-Lindau tumor suppressor EGFLAM 3.220 2.347 2.161 4.572 4.610 4.032 3.660 0.0073055 EGF-like, fibronectin type III and laminin G domains TAF3 3.706 5.861 5.460 7.734 6.883 7.263 3.663 0.0145925 TAF3 RNA polymerase II, TATA box binding protein (TBP)- associated factor, 140 kDa ANKRD45 2.519 2.893 3.388 4.859 5.002 4.393 3.666 0.0046585 ankyrin repeat domain 45 PLCB3 2.944 4.206 3.263 5.738 5.140 4.946 3.673 0.0114305 phospholipase C, beta 3 (phosphatidylinositol-specific) MMP2 2.782 2.782 3.567 6.552 4.623 4.662 3.680 0.0147606 matrix metallopeptidase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) SLC34A2 8.952 11.335 11.869 13.261 13.224 12.168 3.704 0.0397352 solute carrier family 34 (sodium phosphate), member 2 C2orf68 4.507 6.886 7.160 9.052 8.684 8.129 3.711 0.0209486 chromosome 2 open reading frame 68 FBXW5 10.748 9.998 12.047 12.753 12.912 11.892 3.715 0.0464213 F-box and WD repeat domain containing 5 TMLHE 3.999 3.848 4.989 5.945 6.148 5.743 3.718 0.0104390 trimethyllysine hydroxylase, epsilon LEAP2 −0.026 2.038 2.263 3.176 3.176 4.158 3.720 0.0280092 liver expressed antimicrobial peptide 2 ARHGEF5L 5.342 5.874 6.136 7.456 7.238 8.048 3.724 0.0058434 No description LOC642587 8.477 9.820 11.083 11.716 11.838 11.692 3.724 0.0298949 No description RAD52 1.559 3.059 2.075 3.459 4.013 4.705 3.732 0.0189317 RAD52 homolog (S. cerevisiae) CLEC17A 1.559 1.559 2.037 2.404 3.459 4.705 3.732 0.0310146 C-type lectin domain family 17. member A FOXP3 0.974 1.326 2.518 3.437 4.113 2.878 3.741 0.0189424 forkhead box P3 NUDT16 4.003 4.607 4.351 6.571 6.258 5.862 3.750 0.0027897 nudix (nucleoside diphosphate linked moiety X)-type motif 16 CRTC2 6.129 5.896 7.447 8.388 8.462 7.804 3.754 0.0192817 CREB regulated transcription coactivator 2 SORBS2 5.066 6.168 4.588 8.077 7.380 6.314 3.757 0.0229593 sorbin and SH3 domain containing 2 SDK1 2.559 2.663 2.818 5.125 4.572 3.496 3.758 0.0161573 sidekick homolog 1, cell adhesion molecule (chicken) ELN 1.559 1.610 1.803 2.650 3.524 4.875 3.768 0.0183062 elastin ADAMTS5 2.559 2.559 2.559 4.475 3.632 4.697 3.774 0.0068289 ADAM metallopeptidase with thrombospondin type 1 motif, 5 PLD6 2.944 3.838 4.638 6.339 5.374 5.756 3.779 0.0131266 phospholipase D family, member 6 SNORD22 6.337 4.637 4.240 6.557 6.306 7.648 3.785 0.0435288 small nucleolar RNA, C/D box 22 CTPS 6.900 8.059 7.042 8.910 9.069 8.962 3.785 0.0104068 CTP synthase ZNF33A 6.568 6.685 6.342 8.491 9.017 7.685 3.790 0.0080422 zinc finger protein 33A VWF 4.167 4.148 5.370 7.526 6.089 5.768 3.791 0.0250729 von Willebrand factor TMEM212 8.275 6.239 7.339 9.266 9.322 8.900 3.802 0.0197905 transmembrane protein 212 ERAL1 5.920 7.145 5.987 8.574 8.133 7.848 3.805 0.0108649 Era G-protein-like 1 (E. coli) WDR45 8.092 8.771 8.628 10.788 10.431 10.022 3.811 0.0034152 WD repeat domain 45 PRPS1 3.859 5.423 4.365 5.790 6.658 7.209 3.813 0.0166554 phosphoribosyl pyrophosphate synthetase 1 APPBP2 5.803 5.389 5.322 7.320 7.308 7.694 3.813 0.0013346 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 ENC1 5.262 4.309 3.763 6.241 6.279 6.019 3.817 0.0130629 ectodermal-neural cortex 1 (with BTB-like domain) LOC493754 9.558 7.524 8.863 10.597 10.797 11.054 3.820 0.0123853 No description SPEG 6.591 5.929 7.780 7.868 9.084 8.602 3.833 0.0300061 SPEG complex locus ZNF18 2.878 3.997 3.478 6.066 5.422 4.649 3.847 0.0128649 zinc finger protein 18 ZNF93 5.968 5.607 4.730 8.172 6.675 6.863 3.850 0.0223745 zinc finger protein 93 KRT71 2.878 1.264 2.108 2.848 4.062 5.386 3.875 0.0385779 keratin 71 FBXO27 5.611 5.116 5.499 7.942 7.075 7.304 3.889 0.0026900 F-box protein 27 IFITM3 7.795 8.507 8.708 10.765 10.330 9.757 3.896 0.0065487 interferon induced transmembrane protein 3 (1-8U) KIAA1949 10.133 10.009 10.680 12.098 11.902 12.751 3.903 0.0036715 KIAA1949 MRPS18C 4.054 4.062 4.651 6.534 6.023 6.056 3.915 0.0022648 mitochondrial ribosomal protein S18C OLFM2 4.741 4.948 6.461 6.918 7.009 6.822 3.916 0.0317889 olfactomedin 2 C8orf33 6.968 6.619 6.754 8.939 8.420 8.854 3.920 0.0012103 chromosome 8 open reading frame 33 FTSJ3 2.974 5.767 4.751 6.916 6.204 6.725 3.929 0.0303208 FtsJ homolog 3 (E. coli) C14orf73 0.974 3.727 2.531 5.240 4.507 3.758 3.933 0.0379079 chromosome 14 open reading frame 73 C13orf34 1.559 3.024 2.404 4.829 4.382 4.266 3.939 0.0057053 chromosome 13 open reading frame 34 ZNF121 1.974 1.974 2.914 4.164 4.052 3.954 3.943 0.0055150 zinc finger protein 121 C1orf74 1.559 1.804 1.610 2.650 3.840 3.591 3.949 0.0092985 chromosome 1 open reading frame 74 GCHFR 4.921 4.944 6.598 8.580 7.541 6.463 3.951 0.0327276 GTP cyclohydrolase I feedback regulator PLEKHF1 8.348 7.620 7.864 9.846 10.025 9.834 3.952 0.0016170 pleckstrin homology domain containing, family F (with FYVE domain) member 1 CCDC117 4.339 5.197 5.693 7.677 6.627 6.431 3.957 0.0175196 coiled-coil domain containing 117 SLC22A9 −0.026 0.121 −0.026 2.108 2.105 1.348 3.963 0.0030476 solute carrier family 22 (organic anion transporter), member 9 IL2RA 6.697 7.058 7.671 9.254 9.045 8.791 3.963 0.0041397 interleukin 2 receptor, alpha SIN3A 8.009 8.342 8.756 10.630 9.998 10.525 3.968 0.0025909 SINS homolog A, transcription regulator (yeast) HMOX1 6.760 9.598 9.758 10.433 10.640 11.754 3.989 0.0452141 heme oxygenase (decycling) 1 RGS5 2.974 3.052 2.994 5.830 4.840 4.996 4.007 0.0019041 regulator of G-protein signaling 5 SULT2B1 6.087 5.210 6.199 8.273 7.807 7.217 4.019 0.0085196 sulfotransferase family, cytosolic, 2B, member 1 IFITM1 5.908 7.350 5.527 9.056 7.919 7.551 4.032 0.0283262 interferon induced transmembrane protein 1 (9-27) C13orf27 1.559 4.422 3.600 5.616 5.376 5.823 4.046 0.0201957 chromosome 13 open reading frame 27 LOC440896 4.459 3.040 3.914 5.057 5.931 6.140 4.047 0.0138887 No description PLODS 6.824 7.518 8.690 9.573 9.535 9.397 4.047 0.0174060 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 SIRPB2 5.451 4.207 6.089 7.848 7.471 7.418 4.058 0.0080207 signal-regulatory protein beta 2 CP 3.519 3.746 2.559 6.184 5.382 4.584 4.068 0.0124236 ceruloplasmin (ferroxidase) FLJ14107 −0.026 0.611 1.734 3.542 2.636 2.108 4.069 0.0204037 No description TXN 3.475 1.847 2.396 4.273 4.568 4.422 4.072 0.0127137 thioredoxin UNC50 3.188 6.229 4.775 7.242 6.622 6.801 4.074 0.0334444 unc-50 homolog (C. elegans) CROCCL1 5.939 7.136 5.342 7.968 7.630 8.454 4.082 0.0178918 No description DRAM1 4.595 5.433 4.160 7.529 6.587 6.190 4.083 0.0115579 DNA-damage regulated autophagy modulator 1 EPB41L3 1.559 3.059 1.759 4.273 4.471 3.591 4.090 0.0126109 erythrocyte membrane protein band 4.1-like 3 CHRDL2 1.559 3.388 1.559 3.591 4.013 4.851 4.090 0.0246815 chordin-like 2 HNRNPU 9.945 9.746 9.148 11.783 11.735 11.959 4.103 0.0011612 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) APOLD1 4.220 6.184 5.420 8.224 6.587 6.785 4.111 0.0334958 apolipoprotein L domain containing 1 FBXL14 1.559 3.059 1.759 4.013 3.600 3.859 4.114 0.0169624 F-box and leucine-rich repeat protein 14 TWIST1 1.559 1.559 1.559 4.568 3.600 2.173 4.114 0.0275825 twist homolog 1 (Drosophila) CRISPLD2 6.010 6.674 7.651 9.604 8.715 8.065 4.115 0.0186777 cysteine-rich secretory protein LCCL domain containing 2 DAZAP2 10.996 10.743 9.740 13.038 12.734 12.470 4.117 0.0037705 DAZ associated protein 2 ANKRD40 7.960 8.136 7.490 9.883 10.179 9.708 4.119 0.0014973 ankyrin repeat domain 40 THBD 2.559 3.532 3.626 5.918 4.737 4.604 4.127 0.0159133 thrombomodulin TCF4 3.974 4.841 4.132 7.869 6.178 4.929 4.130 0.0416807 transcription factor 4 BCAN 5.273 4.151 5.845 7.527 7.041 7.319 4.132 0.0076577 brevican CH25H 0.974 0.974 1.264 2.404 3.022 3.848 4.134 0.0066347 cholesterol 25-hydroxylase BOC 5.078 4.396 5.271 6.775 6.453 8.234 4.162 0.0107536 Boc homolog (mouse) OSGIN2 3.908 3.763 3.573 5.945 5.967 4.778 4.168 0.0089532 oxidative stress induced growth inhibitor family member 2 BCL2L11 7.969 8.008 8.364 11.356 10.070 9.820 4.175 0.0053016 BCL2-like 11 (apoptosis facilitator) BNIP2 6.553 5.306 5.328 7.779 7.473 7.371 4.184 0.0102494 BCL2/adenovirus E1B 19 kDa interacting protein 2 EFNB1 4.870 6.250 6.213 9.266 8.059 6.935 4.185 0.0201527 ephrin-B1 ALKBH4 9.183 7.891 7.986 10.612 10.282 9.957 4.186 0.0092878 alkB, alkylation repair homolog 4 (E. coli) DDX51 6.484 6.012 7.555 8.475 8.903 8.552 4.194 0.0096124 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 NHEJ1 6.196 6.193 6.859 8.262 8.453 8.418 4.195 0.0016600 nonhomologous end-joining factor 1 ZNF167 1.559 3.719 2.075 3.767 4.144 4.422 4.197 0.0401427 zinc finger protein 167 SLC16A13 −0.026 3.693 4.322 6.306 5.772 4.428 4.224 0.0497490 solute carrier family 16, member 13 (monocarboxylic acid transporter 13) ZNF384 7.921 7.876 8.645 10.022 10.167 9.959 4.235 0.0025372 zinc finger protein 384 FAM83E 5.127 5.297 7.556 8.272 8.163 7.212 4.243 0.0455672 family with sequence similarity 83, member E LRTOMT 3.364 2.357 2.726 4.813 4.939 4.810 4.249 0.0025695 leucine rich transmembrane and 0-methyltransferase domain containing C1GALT1C1 0.974 3.749 2.404 5.051 3.738 4.493 4.254 0.0384144 C1 GALT 1−specific chaperone 1 AHNAK2 4.607 5.185 5.935 7.275 7.143 7.459 4.256 0.0049094 AHNAK nucleoprotein 2 USP45 4.870 5.286 4.892 7.380 6.919 7.057 4.271 0.0008688 ubiquitin specific peptidase 45 EGR2 3.059 4.144 3.459 4.952 5.557 6.938 4.280 0.0131788 early growth response 2 TRIM16 9.698 9.795 11.478 12.839 12.732 11.796 4.281 0.0159977 tripartite motif-containing 16 ZNF836 2.519 2.432 3.778 4.712 5.159 4.533 4.288 0.0108987 zinc finger protein 836 PRRG2 5.720 5.825 7.159 8.670 8.123 7.823 4.294 0.0120338 proline rich Gla (G-carboxyglutamic acid) 2 SV2A 2.296 2.559 3.218 4.809 4.149 5.320 4.295 0.0061865 synaptic vesicle glycoprotein 2A C13orf33 0.974 2.404 0.974 4.507 2.402 3.758 4.296 0.0251297 chromosome 13 open reading frame 33 SECISBP2 7.462 8.773 9.901 11.026 10.881 10.110 4.313 0.0303101 SECIS binding protein 2 CFP 2.671 2.836 3.616 5.020 4.780 5.023 4.314 0.0035687 complement factor properdin C18orf25 6.378 5.876 5.699 8.151 7.812 8.399 4.326 0.0015848 chromosome 18 open reading frame 25 FUCA1 2.247 4.649 3.021 5.494 5.135 4.983 4.330 0.0299263 fucosidase, alpha-L-1, tissue RIPK1 4.473 5.974 5.891 8.099 7.740 6.588 4.331 0.0193500 receptor (TNFRSF)-interacting serine-threonine kinase 1 FLJ39653 2.296 2.327 2.447 4.412 4.421 4.856 4.335 0.0004451 No description PODXL 8.895 7.214 7.787 10.530 9.582 9.906 4.346 0.0127437 podocalyxin-like RRAGD 5.678 6.731 5.726 8.058 7.798 8.180 4.348 0.0046984 Ras-related GTP binding D RPL9 14.258 13.647 14.065 16.381 16.166 16.166 4.356 0.0006078 ribosomal protein L9 SHROOM3 10.537 9.235 8.787 11.864 11.403 10.910 4.358 0.0192548 shroom family member 3 MAP1S 10.790 9.402 11.252 13.111 12.914 12.265 4.360 0.0101581 microtubule-associated protein 1S RAB6C −0.026 0.121 −0.026 1.734 2.105 3.152 4.380 0.0035902 RAB6C, member RAS oncogene family LOC554202 −0.026 −0.026 0.121 1.734 2.105 4.428 4.380 0.0124697 No description PLK1S1 −0.026 −0.026 0.505 3.825 2.105 1.348 4.380 0.0176224 polo-like kinase 1 substrate 1 RFESD −0.026 0.505 −0.026 2.636 1.169 2.108 4.381 0.0120660 Rieske (Fe-S) domain containing FABP4 1.974 3.716 3.403 4.501 4.106 6.237 4.381 0.0426309 fatty acid binding protein 4, adipocyte UBQLNL −0.026 0.121 0.121 2.108 3.176 2.108 4.387 0.0019332 ubiquilin-like PIWIL4 −0.026 −0.026 1.098 2.108 2.636 2.108 4.387 0.0072886 piwi-like 4 (Drosophila) KLF11 7.300 5.085 7.382 9.519 8.434 8.986 4.397 0.0179847 Kruppel-like factor 11 STEAP1 7.373 7.652 7.060 9.790 9.739 8.706 4.401 0.0048097 six transmembrane epithelial antigen of the prostate 1 DDTL 4.899 3.212 4.699 5.775 7.037 5.712 4.402 0.0257191 D-dopachrome tautomerase-like KLF15 0.974 1.328 0.974 2.848 3.324 3.469 4.410 0.0010798 Kruppel-like factor 15 PSMB2 9.064 9.604 9.996 12.138 11.909 10.710 4.413 0.0104175 proteasome (prosome, macropain) subunit, beta type, 2 C4orf14 8.300 7.054 6.932 9.196 9.210 9.159 4.417 0.0118212 chromosome 4 open reading frame 14 EVPL 7.424 6.814 8.832 9.470 9.742 9.568 4.420 0.0188833 envoplakin SLC45A4 3.954 4.587 5.699 7.065 6.860 6.101 4.431 0.0168987 solute carrier family 45, member 4 LAMC3 2.296 2.296 2.419 4.848 4.178 4.445 4.434 0.0008173 laminin, gamma 3 COPS7B 4.605 3.176 3.345 5.948 5.462 5.496 4.441 0.0103814 COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis) CSNK2A1P 8.012 7.602 9.351 10.691 10.168 9.970 4.455 0.0150069 casein kinase 2, alpha 1 polypeptide pseudogene HEXA 6.192 4.579 4.881 7.133 7.044 7.038 4.477 0.0131059 hexosaminidase A (alpha polypeptide) CACNB1 5.178 6.016 7.480 7.782 8.183 8.751 4.491 0.0247007 calcium channel, voltage-dependent, beta 1 subunit PLVAP 1.974 2.649 2.880 5.884 4.817 3.954 4.491 0.0090522 plasmalemma vesicle associated protein GDI1 8.365 5.771 6.430 8.381 8.601 8.868 4.503 0.0476746 GDP dissociation inhibitor 1 C15orf57 4.290 4.739 4.915 6.911 7.300 6.122 4.506 0.0042233 chromosome 15 open reading frame 57 TTC32 5.298 4.139 4.187 6.967 6.977 6.315 4.520 0.0046048 tetratricopeptide repeat domain 32 CWF19L1 3.616 3.979 4.428 6.156 6.751 5.324 4.522 0.0080591 CWF19-like 1, cell cycle control (S. pombe) LRG1 5.273 7.375 8.531 9.560 9.616 9.335 4.548 0.0257084 leucine-rich alpha-2-glycoprotein 1 INTS12 6.566 6.292 7.556 8.702 8.901 8.751 4.549 0.0054520 integrator complex subunit 12 PLIN2 5.317 6.567 6.312 8.931 8.150 7.507 4.564 0.0105756 perilipin 2 C1R 6.996 8.233 7.301 10.255 9.494 9.235 4.572 0.0068857 complement component 1, r subcomponent SIX5 6.439 5.872 5.438 8.222 8.065 7.672 4.572 0.0031451 SIX homeobox 5 NRBP1 9.452 9.012 8.869 11.274 11.228 11.065 4.582 0.0008795 nuclear receptor binding protein 1 DENND1A 6.543 6.088 6.846 9.043 8.859 7.562 4.584 0.0109601 DENN/MADD domain containing 1A PPM1D 6.104 4.872 3.831 7.261 6.724 7.074 4.599 0.0180706 protein phosphatase, Mg2+/Mn2+ dependent, 1D NPTX2 1.559 3.187 1.610 4.273 3.859 3.767 4.620 0.0173047 neuronal pentraxin II S100A3 3.336 5.236 5.924 7.684 7.445 6.025 4.623 0.0335173 S100 calcium binding protein A3 OPLAH 7.418 6.665 8.218 9.568 9.723 9.629 4.629 0.0050154 5-oxoprolinase (ATP-hydrolysing) C15orf61 6.473 6.131 6.033 8.248 8.501 8.401 4.643 0.0004881 chromosome 15 open reading frame 61 TNFRSF6B 5.376 7.437 6.176 9.362 9.111 7.591 4.643 0.0190867 tumor necrosis factor receptor superfamily, member 6b, decoy KRT14 8.427 10.226 9.522 10.643 11.468 13.860 4.646 0.0302840 keratin 14 RTN4RL2 3.188 5.496 6.686 7.686 7.723 7.802 4.682 0.0246247 reticulon 4 receptor-like 2 ACSL4 5.097 3.706 4.445 6.691 6.679 6.119 4.703 0.0063715 acyl-CoA synthetase long-chain family member 4 AP4S1 8.645 6.718 6.823 9.138 8.958 9.724 4.723 0.0252962 adaptor-related protein complex 4, sigma 1 subunit ABHD3 1.974 1.974 2.840 4.572 4.222 4.224 4.749 0.0026477 abhydrolase domain containing 3 C6orf145 9.746 9.469 10.953 12.198 11.721 12.171 4.762 0.0096401 chromosome 6 open reading frame 145 C14orf167 4.059 3.978 4.392 6.319 6.647 5.554 4.774 0.0037206 chromosome 14 open reading frame 167 TSG101 9.205 9.492 9.566 12.128 11.751 11.415 4.787 0.0007467 tumor susceptibility gene 101 REPIN1 8.862 9.184 9.326 12.007 11.452 11.036 4.814 0.0014543 replication initiator 1 SHKBP1 6.278 7.470 8.399 10.660 9.962 8.546 4.815 0.0233085 SH3KBP1 binding protein 1 PSCA 3.593 3.927 3.447 6.085 6.197 5.633 4.824 0.0007145 prostate stem cell antigen PARP10 7.597 6.340 8.117 9.879 9.873 9.670 4.843 0.0050046 poly (ADP-ribose) polymerase family, member 10 CSGALNACT 4.351 5.106 4.231 7.551 6.629 5.119 4.851 0.0357552 chondroitin sulfate N-acetylgalactosaminyltransferase 1 1 SHF 4.042 4.895 5.156 7.439 7.109 6.755 4.867 0.0024206 Src homology 2 domain containing F CXorf15 2.247 3.469 3.089 5.063 5.066 5.752 4.869 0.0033400 No description ASAP3 3.539 3.178 3.322 6.046 4.811 5.606 4.869 0.0035794 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 SMARCA4 9.708 9.428 11.418 12.364 12.470 11.712 4.873 0.0202694 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 SMURF1 10.045 9.779 11.914 12.707 12.604 12.065 4.876 0.0284981 SMAD specific E3 ubiquitin protein ligase 1 SLC25A1 7.758 7.810 8.241 10.446 10.217 10.046 4.881 0.0005610 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 AES 11.175 11.834 12.366 14.354 14.124 13.822 4.892 0.0026685 amino-terminal enhancer of split FAM50B 3.220 4.759 5.313 7.128 7.051 5.804 4.896 0.0192709 family with sequence similarity 50, member B NFE2L1 9.214 9.721 9.958 12.644 12.015 10.778 4.901 0.0110153 nuclear factor (erythroid-derived 2)-like 1 SNAI2 2.747 2.162 2.013 4.457 3.196 5.662 4.906 0.0214213 snail homolog 2 (Drosophila) SPRY2 6.075 4.862 4.273 7.232 6.569 7.407 4.911 0.0148933 sprouty homolog 2 (Drosophila) KIAA0562 5.826 6.878 8.062 9.616 9.150 9.176 4.920 0.0105288 KIAA0562 GOS2 6.337 5.884 4.657 6.379 8.183 9.382 4.921 0.0336876 G0/G1 switch 2 AKNA 7.803 8.030 10.357 10.932 10.968 10.104 4.927 0.0433423 AT-hook transcription factor RPS11 15.724 14.065 14.398 17.032 17.032 16.381 4.982 0.0109386 ribosomal protein S11 DOCK9 3.831 5.107 5.758 8.077 6.696 6.586 4.988 0.0183699 dedicator of cytokinesis 9 RACGAP1 4.605 3.176 4.240 6.666 6.559 6.229 4.989 0.0030691 Rae GTPase activating protein 1 MTERFD2 3.908 5.421 4.598 7.606 6.918 6.857 4.994 0.0040238 MTERF domain containing 2 SLC17A9 2.296 2.357 2.627 4.678 4.503 5.248 4.995 0.0008005 solute carrier family 17, member 9 GOLGA2L1 5.823 4.891 7.105 8.406 7.641 8.147 5.007 0.0171880 No description PIK3R1 5.535 7.277 6.524 9.340 8.850 8.479 5.014 0.0060545 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) ZNF619 1.913 1.688 2.263 5.558 4.239 3.825 5.014 0.0043968 zinc finger protein 619 ODAM 0.974 0.974 0.974 4.062 2.402 3.304 5.025 0.0051213 odontogenic, ameloblast asssociated FZD5 4.724 6.006 7.596 8.523 8.345 8.013 5.058 0.0271097 frizzled homolog 5 (Drosophila) MRPL34 7.990 7.283 9.531 11.428 11.088 9.629 5.085 0.0194505 mitochondrial ribosomal protein L34 ID3 5.720 5.790 6.038 8.813 7.994 8.136 5.085 0.0008580 Description HIRIP3 0.974 0.974 1.264 3.324 3.081 4.062 5.098 0.0012847 HIRA interacting protein 3 FADS6 0.974 1.328 1.643 3.324 4.207 3.469 5.098 0.0017375 fatty acid desaturase domain family, member 6 DSG2 9.885 9.940 9.402 12.013 11.772 12.402 5.170 0.0009563 desmoglein 2 TCHP 5.848 5.513 6.699 8.143 8.482 8.223 5.191 0.0027368 trichoplein, keratin filament binding CYGB 3.593 3.349 4.335 7.187 5.973 5.559 5.207 0.0058972 cytoglobin PPAP2B 5.368 9.445 7.446 10.634 9.829 9.361 5.216 0.0459417 phosphatidic acid phosphatase type 2B SOBP 2.296 2.627 2.296 4.486 4.683 6.119 5.229 0.0033292 sine oculis binding protein homolog (Drosophila) RDH5 4.282 3.922 6.404 6.669 6.858 6.643 5.231 0.0385971 retinol dehydrogenase 5(11-cis/9-cis) ANAPC1 6.128 6.987 8.691 9.047 9.381 9.464 5.258 0.0271420 anaphase promoting complex subunit 1 ADRB3 4.448 5.344 4.801 7.750 7.534 6.056 5.301 0.0098841 adrenergic, beta-3-, receptor PCMT1 8.990 8.666 9.058 11.397 11.474 10.657 5.303 0.0014651 protein-L-isoaspartate (D-aspartate) O-methyltransferase XRCC6 11.845 11.961 12.547 14.755 14.954 14.198 5.304 0.0010691 X-ray repair complementing defective repair in Chinese hamster cells 6 CD34 2.747 3.334 3.704 7.288 5.750 4.806 5.335 0.0103960 CD34 molecule HOXC8 2.296 3.702 4.276 6.251 5.410 6.119 5.341 0.0084006 homeobox C8 CBR3 3.117 3.232 3.222 5.640 6.224 5.148 5.346 0.0011719 carbonyl reductase 3 PDPN 0.974 1.643 0.974 3.922 3.022 4.062 5.348 0.0021596 podoplanin NME2P1 3.336 1.643 2.108 5.380 5.010 4.062 5.348 0.0087583 non-metastatic cells 2, protein (NM23B) expressed in, pseudogene 1 MESTIT1 5.523 3.659 5.357 7.712 7.948 7.639 5.370 0.0033952 MEST intronic transcript 1 (non-protein coding) POLR3E 5.847 6.048 7.847 8.357 8.473 8.488 5.373 0.0233668 polymerase (RNA) III (DNA directed) polypeptide E (80 kD) RHOF 2.747 2.770 5.071 5.501 5.832 5.177 5.388 0.0331213 ras homolog gene family, member F (in filopodia) C17orf103 5.420 5.603 5.389 8.736 7.852 6.923 5.400 0.0057283 chromosome 17 open reading frame 103 SMTNL2 0.974 0.974 3.021 5.454 3.922 2.878 5.400 0.0307698 smoothelin-like 2 TGFB2 7.040 6.197 6.958 8.907 9.316 9.479 5.422 0.0011504 transforming growth factor, beta 2 DDR2 4.137 2.948 3.552 6.806 5.993 5.107 5.430 0.0078235 discoidin domain receptor tyrosine kinase 2 SFRP4 1.974 2.162 2.347 5.262 3.712 4.614 5.470 0.0040023 secreted frizzled-related protein 4 KCNK3 1.559 1.559 1.759 4.851 4.013 4.013 5.476 0.0006539 potassium channel, subfamily K, member 3 SCRIB 7.441 7.845 10.123 10.252 10.691 10.302 5.488 0.0405664 scribbled homolog (Drosophila) PAPPA 3.296 4.931 4.357 7.515 6.817 5.147 5.500 0.0231167 pregnancy-associated plasma protein A, pappalysin 1 ACTL6A 1.974 4.382 2.347 5.295 4.448 5.394 5.554 0.0257398 actin-like 6A FAIM2 2.296 2.448 2.327 5.696 4.811 2.695 5.594 0.0393008 Fas apoptotic inhibitory molecule 2 CIB2 6.066 4.168 6.409 8.904 8.530 7.683 5.639 0.0089854 calcium and integrin binding family member 2 DNAJC6 3.117 3.653 2.925 6.158 4.685 5.664 5.675 0.0053876 DnaJ (Hsp40) homolog, subfamily C, member 6 RABL3 6.044 6.623 7.917 9.529 9.827 8.549 5.676 0.0102602 RAB, member of RAS oncogene family-like 3 NRG1 3.144 4.592 5.195 5.756 7.097 7.487 5.678 0.0154305 neuregulin 1 GZF1 4.548 4.952 6.004 7.086 7.459 7.526 5.682 0.0053124 GDNF-inducible zinc finger protein 1 C6orf15 2.878 3.469 4.826 6.466 7.332 4.983 5.683 0.0188995 chromosome 6 open reading frame 15 FOXC2 1.559 3.247 4.313 5.758 6.734 5.720 5.700 0.0091090 forkhead box C2 (MFH-1, mesenchyme forkhead 1) NDUFV3 8.140 7.141 7.928 10.615 10.657 9.357 5.725 0.0046424 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10 kDa SOX10 8.563 7.788 7.514 10.705 10.319 10.144 5.780 0.0017160 SRY (sex determining region Y)-box 10 SLC2A3 2.296 3.026 4.008 6.010 4.026 6.548 5.814 0.0234497 solute carrier family 2 (facilitated glucose transporter), member 3 PI4K2A 7.661 8.128 8.892 10.898 10.668 10.302 5.815 0.0025802 phosphatidylinositol 4-kinase type 2 alpha HMGB1L1 −0.026 1.098 −0.026 2.108 2.636 3.649 5.862 0.0068964 No description USP54 9.254 6.849 6.335 9.623 8.892 10.393 5.885 0.0439340 ubiquitin specific peptidase 54 H1F0 9.432 8.005 7.107 12.675 9.666 9.735 5.891 0.0433315 H1 histone family, member 0 RASSF4 6.241 5.509 8.215 10.067 9.151 8.068 5.891 0.0286262 Ras association (RalGDS/AF-6) domain family member 4 FANCB 3.966 0.611 2.636 5.270 5.197 4.428 5.903 0.0253684 Fanconi anemia, complementation group B SCNM1 2.878 3.492 5.993 7.141 6.953 5.447 5.934 0.0394405 sodium channel modifier 1 PJA1 5.637 4.921 6.041 8.208 8.256 8.009 5.943 0.0010368 praja ring finger 1 BMF 2.782 5.194 3.730 7.769 6.853 5.373 6.024 0.0183170 Bcl2 modifying factor ST6GALNAC 6.056 6.433 7.295 9.886 9.250 8.215 6.024 0.0067652 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N- 4 acetylgalactosaminide alpha-2,6-sialyltransferase 4 QRSL1 7.711 6.686 8.578 10.354 10.305 9.609 6.037 0.0076255 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 CCND2 3.434 4.267 3.504 6.100 5.879 7.651 6.046 0.0043653 cyclin D2 SLC25A25 9.485 7.681 7.237 10.324 9.836 10.746 6.058 0.0196055 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 HSPA1L 2.247 1.050 2.636 4.282 4.062 5.236 6.060 0.0060330 heat shock 70 kDa protein 1−like PGDN 0.974 1.050 1.050 3.659 1.692 4.235 6.102 0.0217675 podocan SHISA4 1.559 4.957 4.997 7.615 6.521 5.525 6.136 0.0404244 shisa homolog 4 (Xenopus laevis) ZNF570 −0.026 2.038 2.671 4.675 4.657 3.825 6.142 0.0115211 zinc finger protein 570 AIPL1 3.649 2.108 3.335 5.775 6.271 5.023 6.157 0.0048880 aryl hydrocarbon receptor interacting protein-like 1 NFIC 8.833 8.498 8.611 11.564 11.237 10.572 6.175 0.0011228 nuclear factor I/C (CCAAT-binding transcription factor) CD40 4.054 5.253 3.827 7.889 6.690 6.032 6.216 0.0104605 CD40 molecule, TNF receptor superfamily member 5 SLC43A1 3.364 2.859 2.475 6.005 5.660 4.810 6.235 0.0023400 solute carrier family 43, member 1 NDUFA4L2 1.913 1.098 2.912 5.558 4.742 3.152 6.259 0.0186408 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4- like 2 LOC285375 −0.026 −0.026 −0.026 3.664 2.636 2.108 6.327 0.0016946 No description ZNF691 −0.026 0.121 −0.026 1.734 2.636 3.152 6.327 0.0024966 zinc finger protein 691 KRTAP3-2 −0.026 −0.026 −0.026 2.636 2.636 1.348 6.327 0.0042655 keratin associated protein 3-2 NDN −0.026 0.611 1.734 3.974 2.636 3.335 6.327 0.0079263 necdin homolog (mouse) RAB34 7.698 8.519 9.167 11.615 11.262 10.365 6.350 0.0045042 RAB34, member RAS oncogene family LOC283174 2.559 2.585 2.663 3.961 5.256 5.379 6.368 0.0046209 No description PGS1 6.437 6.455 6.986 9.662 9.537 9.035 6.389 0.0004344 phosphatidylglycerophosphate synthase 1 TMEM81 −0.026 1.913 0.505 3.176 2.836 4.592 6.404 0.0101988 transmembrane protein 81 OGN −0.026 −0.026 −0.026 2.836 2.636 2.671 6.483 0.0001136 osteoglycin RDH16 −0.026 1.688 0.505 4.208 3.345 2.671 6.483 0.0070514 retinol dehydrogenase 16 (all-trans) WFDC6 −0.026 −0.026 −0.026 3.664 1.169 2.671 6.483 0.0109094 WAP four-disulfide core domain 6 ITGB7 3.059 3.883 6.051 5.825 6.588 7.233 6.525 0.0382809 integrin, beta 7 TLX3 0.974 1.050 1.050 4.197 3.231 3.758 6.535 0.0005718 T-cell leukemia homeobox 3 ATP8B2 2.974 4.616 3.071 6.083 5.690 6.968 6.569 0.0062525 ATPase, class I, type 8B, member 2 LOC93432 0.974 2.404 1.050 5.120 4.207 3.516 6.570 0.0051965 No description SP4 3.059 3.841 2.650 6.412 5.557 5.778 6.586 0.0017268 Sp4 transcription factor SERPINB7 1.974 4.103 2.973 5.695 5.999 5.493 6.599 0.0053699 serpin peptidase inhibitor, clade B (ovalbumin), member 7 PDE1B 1.559 1.559 2.037 5.825 4.282 3.059 6.600 0.0123484 phosphodiesterase 1B, calmodulin-dependent SS18L2 9.202 7.465 8.341 11.072 11.499 10.566 6.638 0.0040345 synovial sarcoma translocation gene on chromosome 18- like 2 ANXA5 5.656 5.426 5.717 8.417 8.450 8.057 6.648 0.0001949 annexin A5 DRG1 4.208 5.162 6.825 7.921 7.964 6.941 6.651 0.0253231 developmentally regulated GTP binding protein 1 SCN4A 2.782 2.804 3.322 6.557 5.507 5.546 6.692 0.0009670 sodium channel, voltage-gated, type IV, alpha subunit CCT2 11.076 11.298 11.816 14.041 14.159 13.978 6.696 0.0003914 chaperonin containing TCP1, subunit 2 (beta) ASF1A 5.376 5.757 6.051 8.798 8.567 7.591 6.713 0.0020276 ASF1 anti-silencing function 1 homolog A (S. cerevisiae) SETD8 8.587 8.230 10.095 11.160 11.360 11.345 6.763 0.0083899 SET domain containing (lysine methyltransferase) 8 C1orf51 5.931 4.144 6.434 9.111 8.218 8.690 6.766 0.0044935 chromosome 1 open reading frame 51 FMNL3 4.210 4.541 5.829 7.613 6.969 7.662 6.772 0.0044674 formin-like 3 PRO0628 4.851 2.075 3.032 6.412 5.898 4.851 6.849 0.0256427 No description RAB3A 5.167 2.377 3.388 6.166 6.625 6.013 6.859 0.0140015 RAB3A, member RAS oncogene family ERP27 0.974 1.050 3.659 4.062 4.312 3.758 6.885 0.0339655 endoplasmic reticulum protein 27 MHP 5.236 4.507 4.514 8.025 7.919 7.141 6.911 0.0007790 migration and invasion inhibitory protein SOX11 2.559 3.688 3.037 5.838 6.091 5.356 6.946 0.0015188 SRY (sex determining region Y)-box 11 ADC 3.859 5.027 6.508 7.455 7.854 8.607 7.096 0.0104497 arginine decarboxylase C6orf41 3.188 4.322 3.345 6.068 6.173 6.387 7.101 0.0014436 No description EGFL7 0.974 3.758 5.446 7.838 6.596 6.479 7.153 0.0187536 EGF-like-domain, multiple 7 SRGAP2 4.576 5.167 5.126 8.540 7.895 7.430 7.231 0.0007360 SLIT-ROBO Rho GTPase activating protein 2 IL1B −0.026 −0.026 0.121 0.845 2.836 3.335 7.267 0.0169302 interleukin 1, beta SLC43A2 5.537 7.371 6.413 9.663 9.283 8.745 7.312 0.0039708 solute carrier family 43, member 2 RARRES2 0.974 1.691 1.050 3.855 4.207 4.493 7.367 0.0004236 retinoic acid receptor responder (tazarotene induced) 2 ERLIN1 7.385 7.825 8.613 10.403 10.716 10.706 7.369 0.0013131 ER lipid raft associated 1 LRRC37A3 2.247 3.246 5.386 6.089 6.373 6.134 7.404 0.0199163 leucine rich repeat containing 37, member A3 RMND5B 6.374 6.170 7.334 9.674 9.492 9.059 7.406 0.0013239 required for meiotic nuclear division 5 homolog B (S. cerevisiae) FABP3 1.559 1.559 3.095 4.013 4.471 5.986 7.418 0.0098135 fatty acid binding protein 3, muscle and heart (mammary- derived growth inhibitor) LAT 3.954 4.641 7.226 7.445 7.536 7.567 7.437 0.0385226 linker for activation of T cells C21orf91 4.544 6.908 5.162 8.060 8.046 8.444 7.456 0.0090629 chromosome 21 open reading frame 91 LHFP 2.519 1.804 1.759 4.704 3.859 6.147 7.463 0.0060975 lipoma HMGIC fusion partner CCL4 0.974 2.826 1.050 4.197 3.887 5.219 7.529 0.0072134 chemokine (C-C motif) ligand 4 PPP1R3F 2.296 3.507 5.048 6.828 6.424 6.151 7.553 0.0096807 protein phosphatase 1, regulatory (inhibitor) subunit 3F PLAU 7.573 11.673 10.384 13.927 13.321 11.194 7.658 0.0445088 plasminogen activator, urokinase TMOD1 3.412 4.353 4.965 6.501 8.072 6.356 7.695 0.0078342 tropomodulin 1 VNN3 4.215 6.742 6.053 9.694 8.977 8.930 7.740 0.0034582 vanin 3 CNRIP1 0.974 2.531 1.643 5.084 4.605 4.191 7.793 0.0022325 cannabinoid receptor interacting protein 1 CD93 2.974 4.512 3.665 7.936 6.078 5.939 7.806 0.0077982 CD93 molecule TACC1 5.001 5.115 5.156 8.687 8.091 7.182 7.869 0.0014029 transforming, acidic coiled-coil containing protein 1 FOXF2 1.559 1.559 1.559 5.277 3.032 4.554 7.972 0.0061167 forkhead box F2 PUS7L 1.974 2.926 2.860 5.517 5.921 5.136 7.973 0.0009094 pseudouridylate synthase 7 homolog (S. cerevisiae)-like GPIHBP1 0.974 2.878 4.712 6.844 5.874 5.236 7.976 0.0192195 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 MMP3 2.559 3.591 3.591 8.119 6.587 5.285 7.977 0.0058327 matrix metallopeptidase 3 (stromelysin 1, progelatinase) INHBA 2.296 5.376 3.820 6.845 7.069 6.431 8.138 0.0114160 inhibin, beta A FAM70B −0.026 0.121 1.098 4.675 2.636 3.152 8.174 0.0043223 family with sequence similarity 70, member B CYB5R2 7.820 8.017 9.414 11.343 10.857 11.085 8.203 0.0033185 cytochrome b5 reductase 2 STEAP3 5.624 5.837 7.750 9.420 9.391 8.660 8.206 0.0079371 STEAP family member 3 INPP5D 2.944 2.602 3.364 5.821 5.981 6.303 8.210 0.0002701 inositol polyphosphate-5-phosphatase, 145 kDa MMP12 0.974 3.848 2.933 6.888 5.949 5.597 8.226 0.0056846 matrix metallopeptidase 12 (macrophage elastase) HSD11B1 6.630 6.715 7.168 10.372 9.674 9.693 8.249 0.0003484 hydroxysteroid (11-beta) dehydrogenase 1 GMFG 0.974 0.974 3.021 6.066 4.989 3.758 8.250 0.0089140 glia maturation factor, gamma TNFRSF1B 7.518 9.057 10.612 12.261 12.108 10.841 8.287 0.0210752 tumor necrosis factor receptor superfamily, member 1B ABCB4 −0.026 0.505 0.121 3.176 2.105 3.649 8.306 0.0022433 ATP-binding cassette, sub-family B (MDR/TAP), member 4 RPL23P8 1.913 0.121 0.121 3.176 3.176 3.335 8.306 0.0065787 ribosomal protein L23 pseudogene 8 ETV7 2.878 4.083 4.699 7.804 7.164 6.353 8.602 0.0032510 ets variant 7 HSPE1 2.519 2.183 4.869 5.341 7.135 5.624 8.608 0.0176117 heat shock 10 kDa protein 1 (chaperonin 10) DEXI 7.926 8.742 10.539 11.854 11.950 11.379 8.645 0.0114413 Dexi homolog (mouse) ELTD1 2.296 5.344 4.017 8.470 7.135 7.063 8.728 0.0063131 EGF, latrophilin and seven transmembrane domain containing 1 IRX1 6.241 6.512 7.953 9.477 9.651 10.180 8.804 0.0032026 iroquois homeobox 1 PLEKHM1P 4.921 4.337 7.964 8.068 8.331 7.893 8.857 0.0455142 pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene TBX2 2.878 3.799 0.974 6.953 4.831 5.527 8.900 0.0122863 T-box 2 ADRA2C 0.974 3.469 5.310 6.695 6.660 4.983 9.132 0.0407498 adrenergic, alpha-2C-, receptor TGFB1I1 5.507 7.424 9.982 10.717 10.618 9.786 9.151 0.0428933 transforming growth factor beta 1 induced transcript 1 SULT1B1 −0.026 0.121 −0.026 3.176 3.649 2.108 9.196 0.0014866 sulfotransferase family, cytosolic, 1B, member 1 TULP2 −0.026 −0.026 −0.026 2.836 3.176 5.197 9.196 0.0020921 tubby like protein 2 CNTFR −0.026 −0.026 3.088 3.176 3.176 4.857 9.196 0.0314336 ciliary neurotrophic factor receptor ZEB2 1.559 1.559 1.610 5.057 4.774 2.650 9.286 0.0113592 zinc finger E-box binding homeobox 2 NSMCE1 4.821 5.122 8.108 8.658 8.444 8.073 9.530 0.0376830 non-SMC element 1 homolog (S. cerevisiae) DNER 3.117 2.585 4.687 5.860 6.469 7.707 9.681 0.0062418 delta/notch-like EGF repeat containing FABP5 0.974 1.643 3.161 5.240 4.952 4.649 9.914 0.0041289 fatty acid binding protein 5 (psoriasis-associated) LOC642313 −0.026 1.098 3.176 4.443 3.974 4.592 10.165 0.0137206 No description FBLN5 7.684 9.313 6.636 11.296 10.325 11.029 10.167 0.0084659 fibulin 5 TMEM204 2.247 2.348 4.448 7.009 6.049 5.605 10.252 0.0061673 transmembrane protein 204 SRPX −0.026 −0.026 −0.026 4.592 3.345 2.108 10.341 0.0031558 sushi-repeat-containing protein, X-linked LALBA −0.026 −0.026 0.121 1.734 3.345 6.831 10.341 0.0173676 lactalbumin, alpha- ERMP1 4.777 4.990 5.818 9.411 8.406 6.478 10.671 0.0125649 endoplasmic reticulum metallopeptidase 1 LXN 3.649 3.542 1.734 7.069 5.561 5.988 10.701 0.0045940 latexin LOX 7.163 5.936 6.941 10.583 9.839 9.831 10.706 0.0007038 lysyl oxidase MEG3 −0.026 4.443 3.966 5.492 5.735 7.868 10.738 0.0299056 maternally expressed 3 (non-protein coding) SNAI3 0.974 0.974 1.738 4.448 4.406 4.590 10.787 0.0002164 snail homolog 3 (Drosophila) PDGFRB 1.559 2.037 3.388 7.069 5.002 5.027 10.870 0.0059401 platelet-derived growth factor receptor, beta polypeptide 00X18 4.280 4.805 4.521 8.461 7.982 6.548 11.016 0.0024697 COX18 cytochrome c oxidase assembly homolog (S. cerevisiae) PSPH 1.974 2.649 4.042 6.497 6.283 5.511 11.600 0.0033016 phosphoserine phosphatase DUOX2 1.559 2.075 1.759 6.052 5.341 4.309 11.981 0.0010583 dual oxidase 2 GRID1 0.974 0.974 0.974 4.983 4.651 2.404 12.785 0.0073807 glutamate receptor, ionotropic, delta 1 PRDM1 5.135 4.989 5.174 9.340 8.541 8.816 12.829 0.0001351 PR domain containing 1, with ZNF domain IDO1 1.974 4.378 3.196 5.796 6.387 8.068 12.903 0.0066800 Description CST7 0.974 2.108 4.448 5.971 5.797 5.693 12.905 0.0106155 cystatin F (leukocystatin) MSC −0.026 0.121 1.169 5.775 3.825 3.649 13.032 0.0018772 musculin NOL6 3.434 5.048 7.630 7.461 8.783 8.756 13.064 0.0307920 nucleolar protein family 6 (RNA-associated) CXCR7 0.974 4.507 4.753 8.517 7.426 5.736 13.589 0.0179547 chemokine (C-X-C motif) receptor 7 LAMA4 4.821 4.810 5.589 9.523 8.606 7.430 13.788 0.0021489 laminin, alpha 4 MYLK 4.660 4.850 3.527 7.898 7.350 9.620 14.150 0.0022111 myosin light chain kinase C15orf48 6.870 5.942 3.600 9.771 9.857 9.266 14.216 0.0035541 chromosome 15 open reading frame 48 BCAM 7.610 6.838 8.114 11.563 11.740 10.671 14.247 0.0005503 basal cell adhesion molecule (Lutheran blood group) SLC1A5 9.190 9.949 11.409 14.121 14.013 13.037 14.392 0.0027790 solute carrier family 1 (neutral amino acid transporter), member 5 C17orf67 2.671 1.734 5.405 7.154 6.622 6.035 15.467 0.0143216 chromosome 17 open reading frame 67 LMAN2L 5.344 5.547 7.322 9.551 9.611 9.418 16.041 0.0018281 lectin, mannose-binding 2-like IGFL1 1.559 5.636 4.952 9.663 8.916 6.340 16.303 0.0162817 IGF-like family member 1 TIE1 2.296 3.809 4.421 8.631 7.291 6.423 17.464 0.0033507 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 FERMT1 3.220 2.050 2.264 6.429 7.536 4.997 17.937 0.0028619 fermitin family member 1 EPRI 2.878 0.974 4.455 6.089 7.078 7.282 18.382 0.0052072 effector cell peptidase receptor 1 (non-protein coding) CXCL17 5.127 6.275 6.861 11.070 9.330 9.454 18.415 0.0020061 chemokine (C-X-C motif) ligand 17 LOC387763 5.584 6.095 7.544 11.641 10.420 10.089 20.036 0.0012210 No description B3GAT1 2.559 3.476 3.043 5.223 7.459 7.816 20.256 0.0032295 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) WFDC5 −0.026 1.734 4.592 6.306 7.685 6.229 23.783 0.0082947 WAP four-disulfide core domain 5 TNFRSF4 1.913 0.121 4.675 7.896 7.019 4.857 26.648 0.0147329 tumor necrosis factor receptor superfamily, member 4 HSPA12B −0.026 −0.026 3.088 6.271 5.990 4.749 27.369 0.0035004 heat shock 70 kD protein 12B CSN1S1 1.974 1.974 2.013 6.455 6.862 10.189 29.601 0.0015081 casein alpha s1 CACNA1G 0.974 0.974 1.692 6.707 5.527 6.511 32.342 0.0001458 calcium channel, voltage-dependent, T type, alpha 1 G subunit FST 1.559 4.471 3.032 8.467 7.881 9.153 43.247 0.0007575 follistatin S100A7 −0.026 5.581 8.514 11.885 11.071 8.586 44.950 0.0264919 S100 calcium binding protein A7 EDNRB 2.747 2.466 3.917 10.515 9.214 8.289 88.494 0.0002487 endothelin receptor type B

TABLE 6 Differentially Expressed Genes in CD10+ Breast Epithelial Cells Nulliparous (NP) Samples Parous (P) Samples Gene Symbol CD24+ N48 CD24+ N58 CD24+ N43 CD24+ N37 CD24+ N39 CD24+ N40 Pseudo fold change P value Gene description Higher Expression in Nulliparous C1orf54 5.102 3.089 5.104 −0.824 −1.775 0.831 -29.107 0.0002869 chromosome 1 open reading frame 54 THSD4 6.561 9.441 8.353 4.283 4.081 3.953 -19.316 0.000508 thrombospondin, type I, domain containing 4 SNORD5 −0.192 3.962 3.332 −0.824 −0.648 −1.775 -17.826 0.0065107 small nucleolar RNA, C/D box 5 POSTN 9.168 12.303 11.621 7.535 7.574 7.969 −16.525 0.0023939 periostin, osteoblast specific factor COL3A1 11.438 9.014 11.012 4.96 7.398 7.447 −15.897 0.0018316 collagen, type III, alpha 1 NINJ2 3.524 0.251 2.111 −1.775 −1.775 −1.775 −14.779 0.0012771 ninjurin 2 ZFP57 6.093 3.677 0.631 0.173 −0.264 −0.206 −14.752 0.0103284 zinc finger protein 57 homolog (mouse) LRTM2 2.021 2.06 0.925 −1.775 −1.775 −1.775 −13.887 0.0001538 leucine-rich repeats and transmembrane domains 2 DCN 10.671 8.272 11.57 4.488 7.405 7.354 −13.772 0.00479 decorin PI16 8.33 4.395 8.715 2.101 4.938 4.422 −13.703 0.0158439 peptidase inhibitor 16 COL1A2 11.312 8.134 11.217 4.921 7.557 7.552 −12.682 0.0061 collagen, type I, alpha 2 RHOJ 6.664 5.96 6.902 2.852 2.525 3.288 −12.245 0.0001324 ras homolog gene family, member J F10 6.906 2.442 7.022 2.109 3.43 3.093 −12.059 0.0391357 coagulation factor X SFRP2 5.944 6.005 7.791 2.36 3.565 3.768 −11.992 0.0009666 secreted frizzled-related protein 2 CD248 6.793 5.002 7.595 2.521 4.012 3.143 −11.985 0.0021056 CD248 molecule, endosialin PDGFRL 5.035 4.423 5.684 1.459 1.387 1.576 −11.926 0.0001395 platelet-derived growth factor receptor-like CCL8 5.371 3.123 5.509 0.573 1.758 1.936 −11.896 0.0021199 chemokine (C-C motif) ligand 8 AGPHD1 2.021 1.783 1.247 −1.775 −1.775 −1.775 −11.777 0.0000823 aminoglycoside phosphotransferase domain containing 1 COL15A1 7.943 5.164 8.626 3.506 4.729 4.439 −11.347 0.0066209 collagen, type XV, alpha 1 CREB3L1 6.259 2.891 6.607 1.797 2.946 2.758 −11.323 0.0144466 cAMP responsive element binding protein 3-like 1 SCARA5 7.209 3.9 7.207 2.238 3.715 3.427 −11.265 0.0087437 scavenger receptor class A, member 5 (putative) MFAP2 5.023 4.475 6.123 0.573 2.115 2.639 −11.184 0.001016 microfibrillar-associated protein 2 TMEM173 4.551 3.212 5.156 0.415 −0.264 2.53 −11.127 0.0026508 transmembrane protein 173 SNORD27 −1.775 1.699 2.26 −1.775 −1.775 −1.775 −11.106 0.0229996 small nucleolar RNA, C/D box 27 TGFBI 5.658 6.933 8.974 2.565 3.668 3.473 −11.003 0.0012556 transforming growth factor, beta-induced, 68kDa FBLN2 6.431 3.383 5.963 2.443 2.584 2.514 −10.919 0.0059827 fibulin 2 LOC572558 1.689 2.757 2.505 −1.775 −0.648 −0.904 −10.617 0.0002297 No description SEPP1 8.128 7.649 8.746 4.267 4.944 4.804 −10.422 0.0001467 selenoprotein P, plasma, 1 ITM2A 8.629 9.85 9.527 6.096 6.202 6.366 −10.024 0.0002168 integral membrane protein 2A NOXA1 2.391 3.579 4.019 0.173 0.695 0.162 −10.011 0.0005151 NADPH oxidase activator 1 MYOC 5.977 −0.046 3.484 0.173 −0.264 1.075 −9.925 0.0429999 myocilin, trabecular meshwork inducible glucocorticoid response SRPX 6.668 6.897 8.573 3.413 4.377 4.202 −9.549 0.0006024 sushi-repeat-containing protein, X-linked ST7OT2 −0.904 2.884 3.31 −0.311 −0.887 −0.362 −9.486 0.0413665 ST7 overlapping transcript 2 (non-protein coding) CPZ 6.264 3.084 6.187 0.173 2.548 3.043 −9.321 0.0094055 carboxypeptidase Z OLFML1 4.902 1.54 4.336 1.121 0.814 1.436 −9.282 0.0140939 olfactomedin-like 1 LDB2 6.769 4.311 6.747 1.556 3.561 3.09 −9.235 0.0036811 LIM domain binding 2 ABCA8 5.494 2.727 7.114 2.238 3.119 2.311 −9.08 0.0236446 ATP-binding cassette, sub-family A (ABC1), member 8 LSP1 8.582 5.763 9.248 2.406 6.312 5.407 −9.03 0.0182636 lymphocyte-specific protein 1 TMEM132C 4.274 1.241 4.013 0.86 0.848 0.886 −8.892 0.0146648 transmembrane protein 132C FIGF 5.832 4.836 6.788 1.715 3.158 3.452 −8.695 0.0019174 c-fos induced growth factor (vascular endothelial growth factor D) CAT 5.323 5.94 5.212 1.478 2.828 2.664 −8.645 0.0003356 catalase CTSK 7.267 6.416 7.38 3.306 3.73 4.552 −8.63 0.0003212 cathepsin K DLK1 4.533 4.081 6.642 1.299 2.621 1.436 −8.553 0.001999 delta-like 1 homolog (Drosophila) PENK 1.541 3.971 5.292 1.757 0.515 0.886 −8.485 0.016437 proenkephalin CMTM5 3.967 3.924 2.33 −0.104 0.886 0.327 −8.458 0.000845 CKLF-like MARVEL transmembrane domain containing 5 PTGDS 8.456 6.809 10.25 3.743 6.499 6.516 −8.379 0.0150662 prostaglandin D2 synthase 21 kDa (brain) ISLR 5.665 3.479 5.466 2.101 2.402 2.488 −8.362 0.0035966 immunoglobulin superfamily containing leucine-rich repeat FAM198B 9.132 10.015 9.316 6.093 6.761 6.912 −8.218 0.0002726 family with sequence similarity 198, member B OAF 8.246 5.745 8.877 5.057 5.221 5.503 −8.139 0.0130157 OAF homolog (Drosophila) OLFML3 7.383 4.852 7.283 1.854 4.11 4.501 −7.989 0.0077091 olfactomedin-like 3 CSTA 6.315 8.863 7.883 4.886 4.535 5.5 −7.982 0.0037419 cystatin A (stefin A) DPT 8.014 3.514 6.971 2.748 4.059 3.979 −7.953 0.0301774 dermatopontin TNNT1 5.751 5.666 4.726 3.489 0.924 2.682 −7.911 0.0023868 troponin T type 1 (skeletal, slow) CNRIP1 6.467 3.081 5.326 2.313 3.139 2.348 −7.881 0.0160335 cannabinoid receptor interacting protein 1 PARVB 6.455 2.539 4.339 1.299 1.362 1.928 −7.873 0.008587 parvin, beta ELN 6.422 4.033 6.521 1.065 3.701 3.353 −7.826 0.0083423 elastin MCEE 2.854 5.603 5.238 2.638 1.387 1.779 −7.805 0.007053 methylmalonyl CoA epimerase OLFML2B 5.402 4.001 5.188 2.335 1.758 2.226 −7.791 0.0006382 olfactomedin-like 2B JAM2 5.895 5.363 5.074 2.124 3.218 2.195 −7.729 0.000357 junctional adhesion molecule 2 TM4SF18 6.191 2.257 0.315 −0.311 −0.887 −0.688 −7.701 0.0147378 transmembrane 4 L six family member 18 HSPA12B 5.06 2.669 5.254 1.556 2.324 2.074 −7.62 0.0094591 heat shock 70kD protein 12B INS-IGF2 9.689 6.133 8.804 3.204 6.386 6.342 −7.614 0.0215175 No description TNFRSF4 5.722 2.004 5.474 0.631 2.797 2.4 −7.592 0.0322029 tumor necrosis factor receptor superfamily, member 4 CABP1 1.587 1.699 1.148 −1.775 −0.012 −1.775 −7.584 0.0017615 calcium binding protein 1 SSBP2 5.056 7.455 8.981 4.533 4.441 5.178 −7.582 0.0198583 single-stranded DNA binding protein 2 C5orf13 5.225 7.535 6.988 4.068 4.276 3.885 −7.569 0.0038048 chromosome 5 open reading frame 13 SDPR 5.96 8.702 7.915 4.045 5.252 4.996 −7.565 0.0048358 serum deprivation response PHLDA3 7.615 10.055 9.532 6.19 6.616 6.804 −7.548 0.004531 pleckstrin homology-like domain, family A, member 3 LY96 4.804 1.114 2.602 −0.311 1.49 −0.362 −7.534 0.0192144 lymphocyte antigen 96 CRISPLD1 5.01 8.092 7.816 4.661 4.884 5.192 −7.465 0.0260192 cysteine-rich secretory protein LCCL domain containing 1 PTPRZ1 3.81 7.139 6.606 3.709 3.483 3.945 −7.451 0.0250411 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 TNFAIP3 7.863 11.202 10.946 7.399 8.313 8.054 −7.406 0.0334221 tumor necrosis factor, alpha-induced protein 3 HNRPDL 9.386 12.615 12.062 9.177 8.983 9.52 −7.386 0.0232883 heterogeneous nuclear ribonucleoprotein D-like CRYM 2.803 6.993 4.492 1.623 2.261 1.46 −7.303 0.0100501 crystallin, mu MLLT11 3.708 4.372 4.832 1.513 1.948 1.471 −7.251 0.0003999 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila): translocated to, 11 SNAP25 1.867 5.049 4.604 2.205 1.033 1.609 −7.178 0.0217786 synaptosomal-associated protein, 25kDa HOXD3 3.014 1.715 3.239 0.173 0.283 0.162 −7.166 0.0013572 homeobox D3 COL1A1 11.804 9.592 13.092 7.357 8.972 9.077 −7.122 0.0074637 collagen, type I, alpha 1 SUMF1 3.663 5.562 6.011 2.269 3.016 2.735 −7.098 0.005449 sulfatase modifying factor 1 CPE 7.988 9.977 8.88 4.974 7.174 6.789 −6.977 0.0059111 carboxypeptidase E LOXHD1 1.719 4.266 3.613 −0.104 0.886 0.814 −6.957 0.0045045 lipoxygenase homology domains 1 COL11A1 5.27 7.581 7.849 4.638 4.787 4.877 −6.938 0.0126987 collagen, type XI, alpha 1 IFI44 3.953 3.678 2.821 1.065 0.848 0.886 −6.926 0.0004572 interferon-induced protein 44 NSMCE4A 4.008 4.325 5.166 1.188 1.546 2.682 −6.862 0.0013358 non-SMC element 4 homolog A (S. cerevisiae) MFAP5 5.807 2.506 4.877 1.698 2.101 2.342 −6.849 0.0149832 microfibrillar associated protein 5 MEOX2 4.887 2.352 3.338 0.573 0.924 0.251 −6.801 0.0021421 mesenchyme homeobox 2 SRBD1 1.871 2.776 2.97 −0.104 −0.887 1.408 −6.763 0.0055785 S1 RNA binding domain 1 GAS1 5.686 7.409 8.211 4.66 4.482 5.362 −6.724 0.0085405 growth arrest-specific 1 PLAC9 5.641 3.381 5.994 1.459 2.548 3.246 −6.719 0.0085998 placenta-specific 9 IGFBP7 8.81 6.739 9.172 4.745 6.165 6.083 −6.62 0.0065536 insulin-like growth factor binding protein 7 NPR1 5.142 1.835 4.238 1.366 1.513 1.609 −6.612 0.0176991 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) MAGED1 5.427 7.934 6.354 5.172 2.715 4.402 −6.552 0.0128847 melanoma antigen family D, 1 OGN 8.73 5.19 8.837 3.375 6.158 5.667 −6.405 0.0363311 osteoglycin FMO1 4.039 4.435 4.937 1.366 2.107 1.948 −6.38 0.0003499 flavin containing monooxygenase 1 FBN1 7.256 6.448 8.561 3.808 4.583 4.743 −6.375 0.001227 fibrillin 1 VASH2 4.593 6.943 7.239 4.082 4.186 4.574 −6.341 0.0196072 vasohibin 2 POTEE 0.888 2.06 2.758 −1.775 −0.012 −0.012 −6.33 0.0055055 POTE ankyrin domain family, member E LMBR1L 5.318 6.496 6.378 3.15 3.776 3.719 −6.319 0.0008156 limb region 1 homolog (mouse)-like COLEC12 7.061 3.646 6.583 2.121 3.927 3.927 −6.303 0.023417 collectin sub-family member 12 KCNMB4 3.198 2.812 4.689 1.818 1.099 0.162 −6.275 0.0041962 potassium large conductance calcium-activated channel, subfamily M, beta member 4 CCDC152 7.213 6.032 7.58 3.806 4.935 4.418 −6.254 0.0017887 coiled-coil domain containing 152 ADAMTS18 3.089 4.656 5.578 2.37 2.019 1.837 −6.217 0.0056994 ADAM metallopeptidase with thrombospondin type 1 motif, 18 CD34 8.863 3.223 5.792 1.982 4.356 3.158 −6.207 0.0422759 CD34 molecule EMILIN2 5.621 4.088 5.854 2.966 3.231 2.533 −6.16 0.0037168 elastin microfibril interfacer 2 OR4E2 1.797 0.251 1.715 −0.824 −1.775 −1.775 −6.149 0.0015468 olfactory receptor, family 4, subfamily E, member 2 RCAN2 4.959 4.747 5.451 2.129 3.479 2.171 −6.14 0.0014553 regulator of calcineurin 2 ACTA2 6.139 8.987 8.32 5.319 5.749 5.703 −6.136 0.0123453 actin, alpha 2, smooth muscle, aorta CXCR4 5.908 5.696 3.497 1.525 2.795 3.297 −6.108 0.0090985 chemokine (C-X-C motif) receptor 4 COL14A1 8.194 9.149 9.493 6.543 5.763 6.697 −6.089 0.0009737 collagen, type XIV, alpha 1 TMEM55A 3.174 4.774 4.45 1.846 1.82 1.999 −6.082 0.0023167 transmembrane protein 55A FN1 6.972 4.777 7.377 3.927 4.774 4.001 −6.075 0.0139536 fibronectin 1 KLHL22 2.643 4.542 4.48 1.679 1.944 1.72 −6.052 0.006143 kelch-like 22 (Drosophila) C20orf46 1.689 2.526 1.494 −1.775 0.988 −0.904 −6.033 0.0077857 chromosome 20 open reading frame 46 HTRA1 8.218 6.817 7.592 4.391 5 5.532 −6.031 0.0013715 HtrA serine peptidase 1 ROBO1 5.017 7.203 7.08 4.613 3.944 4.351 −6.02 0.0092509 roundabout, axon guidance receptor, homolog 1 (Drosophila) STC1 11.369 6.744 7.072 4.163 5.522 4.742 −5.982 0.0090842 stanniocalcin 1 C9orf25 5.049 7.374 7.465 4.57 4.719 4.886 −5.975 0.0191822 chromosome 9 open reading frame 25 COL6A6 5.493 3.608 6.676 2.799 3.378 2.921 −5.947 0.014242 collagen, type VI, alpha 6 RSRC1 1.602 3.047 3.019 0.173 0.283 0.478 −5.935 0.0022408 arginine/serine-rich coiled-coil 1 CALHM2 4.107 3.432 4.593 1.949 1.546 1.513 −5.901 0.0007512 calcium homeostasis modulator 2 TNN 7.528 5.3 7.485 3.498 4.975 4.706 −5.871 0.0089719 tenascin N ST8SIA2 6.819 8.269 7.329 4.539 4.779 5.207 −5.858 0.0008378 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 C7orf55 3.595 5.857 5.109 2.765 2.569 2.06 −5.816 0.0045596 chromosome 7 open reading frame 55 PCOLCE 8.195 6.361 9.153 4.442 5.656 5.939 −5.815 0.0082114 procollagen C-endopeptidase enhancer S100A4 6.136 4.191 7.067 3.014 3.598 3.991 −5.808 0.0123381 S100 calcium binding protein A4 SGCE 7.219 9.297 8.943 6.287 6.414 6.526 −5.773 0.0070802 sarcoglycan, epsilon TRPV6 1.888 5.075 3.751 1.228 0.695 1.779 −5.748 0.0141518 transient receptor potential cation channel, subfamily V, member 6 UBE2V1 0.609 1.699 3.102 −0.824 −0.012 −1.775 −5.745 0.0054346 ubiquitin-conjugating enzyme E2 variant 1 CD99 9.28 5.505 8.513 3.479 6.687 6 −5.706 0.0485662 CD99 molecule TSC22D1 8.836 9.579 9.258 5.975 7.45 6.746 −5.704 0.0012098 TSC22 domain family, member 1 TRIL 4.539 6.374 6.051 2.841 3.674 3.542 −5.691 0.0039214 TLR4 interactor with leucine-rich repeats BDKRB2 5.325 4.576 6.703 2.832 2.656 3.356 −5.63 0.0025621 bradykinin receptor B2 MTRNR1 14.554 14.158 15.551 11.466 12.062 13.58 −5.625 0.0057137 No description NTF3 5.626 8.418 8.063 5.836 5.386 5.578 −5.598 0.0349381 neurotrophin 3 CPVL 4.276 2.656 3.392 0.173 1.387 1.075 −5.591 0.0020062 carboxypeptidase, vitellogenic-like C6orf115 2.461 4.636 4.254 1.773 1.176 2.042 −5.581 0.0087959 chromosome 6 open reading frame 115 IL33 6.764 4.553 6.263 4.015 2.423 3.789 −5.556 0.0068527 interleukin 33 HLA-DQB1 5.54 4.587 3.428 1.623 2.261 2.124 −5.516 0.0027624 major histocompatibility complex, class II, DQ beta 1 MX2 5.186 2.845 4.983 2.669 2.521 2.169 −5.51 0.0180167 myxovirus (influenza virus) resistance 2 (mouse) ST3GAL4 5.967 4.347 6.76 2.593 3.93 3.507 −5.501 0.0078558 STS beta-galactoside alpha-2,3-sialyltransferase 4 LOC339568 1.797 2.06 3.476 1.029 −1.775 0.429 −5.454 0.0101681 No description RFX5 4.52 6.697 6.669 4.233 4.198 4.222 −5.452 0.0214223 regulatory factor X, 5 (influences HLA class II expression) H3F3C 8.303 10.66 8.956 6.55 5.923 6.513 −5.437 0.0017329 H3 histone, family SC UBQLNL 1.091 2.978 1.753 −0.311 −0.887 −0.688 −5.43 0.001803 ubiquilin-like SIX5 4.715 6.541 6.443 3.638 4.102 3.925 −5.424 0.0070122 SIX homeobox 5 SPON2 7.184 5.652 8.637 3.24 4.748 5.049 −5.41 0.0069586 spondin 2, extracellular matrix protein ZNF630 0.644 1.893 2.33 −0.104 −0.887 −0.688 −5.404 0.0038263 zinc finger protein 630 TACC2 5.639 5.612 6.86 3.185 4.028 3.91 −5.375 0.0019103 transforming, acidic coiled-coil containing protein 2 ENPP2 10.147 4.572 7.142 3.92 4.718 4.87 −5.367 0.0336739 ectonucleotide pyrophosphatase/phosphodiesterase 2 CDH23 5.288 6.717 6.119 3.853 3.204 3.695 −5.366 0.0012027 cadherin-related 23 GLT8D2 7.101 7.934 8.22 4.946 5.698 5.513 −5.355 0.0010517 glycosyltransferase 8 domain containing 2 ITFG1 4.926 6.947 6.402 3.874 3.589 4.533 −5.331 0.0074937 integrin alpha FG-GAP repeat containing 1 ODZ1 2.879 5.083 5.058 2.646 2.63 2.661 −5.324 0.0250869 odz, odd Oz/ten-m homolog 1 (Drosophila) RIN2 5.406 7.715 6.79 4.387 4.383 4.518 −5.289 0.0059469 Ras and Rab interactor 2 C14orf159 4.418 5.87 6.418 3.463 4.017 3.139 −5.282 0.0081498 chromosome 14 open reading frame 159 C15orf32 3.499 2.567 2.943 0.573 0.17 0.552 −5.266 0.0002941 chromosome 15 open reading frame 32 IFRD1 8.899 11.138 10.754 8.218 8.359 8.584 −5.261 0.0144781 interferon-related developmental regulator 1 GPR124 6.905 5.121 8.362 3.17 4.583 4.511 −5.254 0.0088517 G protein-coupled receptor 124 KATNAL2 1.855 3.15 3.313 0.762 0.924 0.552 −5.235 0.0036396 katanin p60 subunit A-like 2 SLIT3 7.064 5.129 6.857 4.475 4.341 4.633 −5.212 0.0106003 slit homolog 3 (Drosophila) CAPN6 4.869 6.308 7.831 3.409 4.038 3.928 −5.206 0.0067303 calpain 6 PODN 8.751 4.235 6.561 2.721 4.719 4.182 −5.203 0.0275281 podocan ACOX2 2.16 3.454 4.774 0.415 1.616 1.075 −5.202 0.0070731 acyl-CoA oxidase 2, branched chain SOSTDC1 5.669 7.193 5.447 3.794 3.069 4.381 −5.199 0.00432 sclerostin domain containing 1 LMOD1 6.678 9.189 9.06 6.107 6.812 6.301 −5.197 0.0225263 leiomodin 1 (smooth muscle) FAM184A 4.925 7.544 7.02 4.495 4.731 4.645 −5.185 0.0211211 family with sequence similarity 184, member A MEF2C 6.151 6.243 4.93 3.338 3.732 3.869 −5.184 0.0024426 myocyte enhancer factor 2C EPSTI1 3.708 1.388 3.015 1.267 0.647 −0.012 −5.164 0.012497 epithelial stromal interaction 1 (breast) SAMD11 2.005 3.595 2.891 1.228 0.283 0.162 −5.157 0.0033691 sterile alpha motif domain containing 11 PDE1B 4.475 2.184 4.334 1.969 1.862 2.048 −5.154 0.0256622 phosphodiesterase 1B, calmodulin-dependent FUCA2 4.002 4.399 4.646 1.494 2.048 2.283 −5.144 0.0004357 fucosidase, alpha-L-2, plasma IGFBP5 8.858 11.154 9.995 7.282 8.151 7.639 −5.12 0.0055663 insulin-like growth factor binding protein 5 CXCL12 8.481 6.43 10.048 5.217 6.152 6.142 −5.06 0.0154268 chemokine (C-X-C motif) ligand 12 SPARC 11.099 12.471 11.859 9.434 9.526 9.75 −5.039 0.001491 secreted protein, acidic, cysteine-rich (osteonectin) CHN1 3.529 2.572 3.637 0.762 1.305 0.552 −5.034 0.0010374 chimerin (chimaerin) 1 EMP1 10.735 7.104 9.657 6.459 7.548 7.326 −5.033 0.0371031 epithelial membrane protein 1 BMP5 5.501 6.837 5.976 4.507 1.82 3.851 −5.03 0.0053495 bone morphogenetic protein 5 PIGP 4.307 4.363 3.975 1.672 2.994 1.645 −5.028 0.0026994 phosphatidylinositol glycan anchor biosynthesis, class P CTSD 8.235 9.612 10.415 6.897 7.29 7.35 −4.999 0.0050719 cathepsin D PTPLAD2 2.888 1.126 3.759 0.573 0.17 1.277 −4.977 0.021539 protein tyrosine phosphatase-like A domain containing 2 CYYR1 4.245 3.175 0.945 0.86 0.515 0.886 −4.975 0.0260564 cysteine/tyrosine-rich 1 A2M 10.21 11.185 10.085 8.256 7.775 8.455 −4.959 0.001124 alpha-2-macroglobulin OXTR 9.258 11.522 11.028 8.719 8.512 8.793 −4.956 0.012258 oxytocin receptor SEMA3G 8.578 5.278 6.183 3.543 3.95 3.875 −4.951 0.0054418 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G EEPD1 6.508 6.351 5.769 4.046 4.267 3.202 −4.942 0.0009594 endonuclease/exonuclease/phosphatase family domain containing 1 IGF2AS 2.546 0.623 1.942 −0.311 −0.887 −0.362 −4.937 0.0041676 insulin-like growth factor 2 antisense MXRA5 5.979 7.043 8.098 4.573 4.956 4.744 −4.922 0.0041153 matrix-remodelling associated 5 TIMP2 10.148 9.257 10.371 6.869 8.079 7.984 −4.899 0.002414 TIMP metallopeptidase inhibitor 2 LUM 9.048 7.399 9.517 4.192 7.022 7.227 −4.89 0.0182707 lumican MATN2 6.37 9.054 8.277 5.406 6.181 5.987 −4.889 0.0159877 matrilin 2 CEACAM1 6.148 9.01 7.627 5.3 5.343 5.718 −4.869 0.0132976 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) DYSF 6.263 4.874 2.824 2.425 3.172 2.598 −4.843 0.0370208 dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) VSIG2 2.735 1.588 −0.648 −0.311 −0.887 −0.688 −4.841 0.0408829 V-set and immunoglobulin domain containing 2 PI15 6.039 7.951 8.63 5.303 5.899 5.681 −4.824 0.0188238 peptidase inhibitor 15 CHRDL1 6.044 3.319 6.29 1.797 4.023 3.633 −4.813 0.0406611 chordin-like 1 CPXM2 7.454 6.719 6.34 2.974 5.187 4.938 −4.812 0.0052272 carboxypeptidase X (M14 family), member 2 SRPX2 4.013 1.942 3.921 1.556 1.645 1.747 −4.81 0.0234993 sushi-repeat-containing protein, X-linked 2 C2 5.707 3.895 6.599 2.711 4.094 3.441 −4.809 0.0219196 complement component 2 SLC9A9 3.239 2.02 4.954 0.86 2.689 0.886 −4.806 0.0386592 solute carrier family 9 (sodium/hydrogen exchanger), member 9 TMEM144 3.579 5.656 4.887 2.624 1.408 2.832 −4.8 0.005328 transmembrane protein 144 ALPK2 3.12 5.183 3.207 0.86 2.206 2.06 −4.789 0.0117071 alpha-kinase 2 DHDH 4.356 5.126 5.533 2.724 3.121 2.875 −4.761 0.0016184 dihydrodiol dehydrogenase (dimeric) KDELR3 3.324 1.966 3.149 0.173 0.283 1.075 −4.752 0.002268 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 ECM2 4.607 2.847 5.11 1.366 2.53 2.358 −4.751 0.0114452 extracellular matrix protein 2, female organ and adipocyte specific LHFP 7.357 8.726 8.838 6.479 6.344 6.553 −4.747 0.0056572 lipoma HMGIC fusion partner GPNMB 10.06 10.578 9.963 7.886 7.719 8.18 −4.737 0.0003856 glycoprotein (transmembrane) nmb LYRM5 3.255 3.677 2.401 2.171 0.695 0.162 −4.72 0.0088374 LYR motif containing 5 HOXA2 3.298 3.521 3.25 −0.311 2.692 1.059 −4.72 0.0129427 homeobox A2 GLB1 3.53 5.904 4.771 2.84 2.314 2.533 −4.717 0.0073056 galactosidase, beta 1 IGFBP3 12.05 11.696 10.87 9.46 9.13 9.497 −4.711 0.0013186 insulin-like growth factor binding protein 3 PIK3C2B 6.308 8.495 5.841 3.653 4.073 4.292 −4.707 0.0033262 phosphoinositide-3-kinase, class 2, beta polypeptide EFEMP1 8.705 10.875 10.916 8.36 8.056 8.684 −4.699 0.0209759 EGF-containing fibulin-like extracellular matrix protein 1 RASSF2 5.285 3.354 4.459 1.659 2.775 2.228 −4.692 0.0060857 Ras association (RalGDS/AF-6) domain family member 2 ITM2B 10.108 11.103 11.165 8.408 8.935 8.754 −4.691 0.0016914 integral membrane protein 2B CYP1B1 8.524 8.017 9.48 5.798 6.88 6.644 −4.655 0.0032046 cytochrome P450, family 1, subfamily B, polypeptide 1 ADAMTS14 0.871 2.391 4.04 0.173 0.283 −0.206 −4.652 0.0116713 ADAM metallopeptidase with thrombospondin type 1 motif, 14 PLAT 8.741 11.05 8.947 6.734 6.687 7.058 −4.637 0.0028125 plasminogen activator, tissue DFNA5 2.981 5.301 4.84 3.088 2.073 2.54 −4.636 0.0216892 deafness, autosomal dominant 5 ITIH3 3.169 5.005 4.567 2.794 2.352 1.66 −4.63 0.0090205 inter-alpha (globulin) inhibitor H3 PIM3 7.097 9.482 8.654 6.346 6.508 6.443 −4.627 0.0113844 pim-3 oncogene DKK2 2.819 0.988 4.392 0.762 0.609 0.552 −4.626 0.0233412 dickkopf homolog 2 (Xenopus laevis) BTN3A3 4.449 3.633 4.672 1.426 2.745 1.513 −4.62 0.0022179 butyrophilin, subfamily 3, member A3 EPHX1 7.496 6.352 8.954 5.041 5.337 5.29 −4.614 0.0059255 epoxide hydrolase 1, microsomal (xenobiotic) LMCD1 5.885 4.559 5.606 2.201 3.68 3.549 −4.612 0.0047757 LIM and cysteine-rich domains 1 PTPRN 1.896 1.998 2.976 0.415 −0.264 −0.206 −4.61 0.0012413 protein tyrosine phosphatase, receptor type, N EDAR 0.251 2.52 1.998 0.173 −0.264 −0.206 −4.609 0.0227216 ectodysplasin A receptor ADAMTS4 10.316 9.462 10.936 7.259 8.472 8.169 −4.601 0.0032461 ADAM metallopeptidase with thrombospondin type 1 motif, 4 LRRC4C 3.772 5.158 5.26 2.908 3.059 2.575 −4.597 0.0057652 leucine rich repeat containing 4C ST3GAL5 4.547 2.921 4.746 2.109 2.352 2.52 −4.578 0.012781 STS beta-galactoside alpha-2,3-sialyltransferase 5 MBNL1 8.986 10.216 10.148 7.925 7.649 8.025 −4.567 0.003475 muscleblind-like (Drosophila) AQP7P3 3.352 4.56 3.835 1.244 2.06 1.645 −4.564 0.0015611 aquaporin 7 pseudogene 3 PLP1 2.887 4.511 3.556 1.366 1.033 1.609 −4.562 0.0021128 proteolipid protein 1 TARBP1 3.286 5.46 5.848 2.887 3.275 3.274 −4.552 0.0305996 TAR (HIV-1) RNA binding protein 1 RCVRN 4.539 3.957 5.012 2.354 3.596 1.758 −4.548 0.0090914 recoverin NEGR1 4.901 2.121 4.268 2.083 2.512 1.966 −4.548 0.0499406 neuronal growth regulator 1 FAM83B 3.847 6.33 5.991 3.809 3.316 3.81 −4.538 0.0277599 family with sequence similarity 83, member B TRIM6 0.403 2.17 2.111 −0.824 −0.648 −0.012 −4.537 0.00698 tripartite motif-containing 6 MAPK12 4.966 0.862 2.809 0.631 0.415 0.814 −4.526 0.0298054 mitogen-activated protein kinase 12 PCDHB3 2.073 3.738 2.33 0.967 −0.104 1.107 −4.522 0.0074193 protocadherin beta 3 GBP2 7.899 8.739 8.77 5.588 6.909 6.565 −4.513 0.0031974 guanylate binding protein 2, interferon-inducible APOL4 6.368 4.95 3.326 3.436 2.777 2.409 −4.51 0.0234578 apolipoprotein L, 4 SEMA6D 4.489 6.479 5.744 3.573 3.397 4.07 −4.504 0.0098233 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D EPB41L3 4.187 3.827 5.136 1.698 2.706 2.016 −4.501 0.0023095 erythrocyte membrane protein band 4.1-like 3 C8orf85 3.532 5.285 3.565 1.868 1.362 2.567 −4.501 0.0062667 chromosome 8 open reading frame 85 MTUS1 6.921 6.272 7.408 4.148 4.753 5.154 −4.493 0.0020276 microtubule associated tumor suppressor 1 CASP4 6.7 8.104 7.882 5.714 5.317 5.877 −4.492 0.0044051 caspase 4, apoptosis-related cysteine peptidase PQLC3 2.812 2.579 2.574 0.415 0.283 1.779 −4.482 0.0061143 PQ loop repeat containing 3 CASD1 4.675 6.423 6.337 3.675 3.443 4.261 −4.477 0.0072412 CAS1 domain containing 1 GOLGA8B 4.504 6.736 6.912 4.755 4.138 4.361 −4.461 0.0363383 golgin A8 family, member B CA2 4.99 7.396 6.266 4.112 4.415 4.01 −4.452 0.0100959 carbonic anhydrase II CMAH 3.59 2.392 3.438 1.121 1.07 1.436 −4.45 0.0030128 cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase) pseudogene CPXM1 8.32 8.212 8.809 6.059 6.638 6.55 −4.447 0.0008307 carboxypeptidase X (M14 family), member 1 TMEM176B 6.098 4.261 7.562 2.109 4.715 4.081 −4.445 0.0287308 transmembrane protein 176B FBXL7 6.395 5.072 6.414 4.109 4.102 4.263 −4.444 0.0054146 F-box and leucine-rich repeat protein 7 NRBP2 5.752 8.804 8.237 5.335 6.093 6.086 −4.443 0.0452436 nuclear receptor binding protein 2 TCN2 5.838 4.48 4.924 2.57 2.775 3.257 −4.435 0.0019704 transcobalamin II OTOF 2.596 4.562 3.847 1.698 1.408 2.19 −4.434 0.0096745 otoferlin TCF4 10.509 7.186 8.39 5.056 6.695 6.249 −4.413 0.0103155 transcription factor 4 SERPINF1 8.952 8.484 9.443 5.967 7.307 6.813 −4.404 0.0021271 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 TSPAN3 5.512 7.033 7.079 4.94 3.639 4.214 −4.403 0.0044545 tetraspanin 3 SKP2 2.196 5.213 3.618 1.606 0.848 1.486 −4.385 0.010523 S-phase kinase-associated protein 2 (p45) NRP1 8.23 6.994 7.52 5.046 5.753 5.391 −4.375 0.0016985 neuropilin 1 LOC1001889 2.221 4.533 1.865 1.641 −0.264 0.713 −4.374 0.0206511 No description 47 ADAM12 4.417 5.669 6.037 3.119 3.562 3.55 −4.345 0.0049632 ADAM metallopeptidase domain 12 SERPINI1 4.531 5.866 5.337 2.492 3.464 3.218 −4.344 0.0025692 serpin peptidase inhibitor, clade I (neuroserpin), member 1 COL6A3 8.045 5.973 9.411 4.291 6.235 5.927 −4.34 0.0248029 collagen, type VI, alpha 3 RASAL1 0.554 3.82 2.29 0.173 1.099 0.162 −4.337 0.0495256 RAS protein activator like 1 (GAP1 like) FLCN 6.52 8.294 8.427 6.11 6.187 6.18 −4.329 0.0213858 folliculin PLSCR4 5.443 6.97 7.012 3.435 4.904 4.138 −4.308 0.0046569 phospholipid scramblase 4 PCDHB14 2.457 4.212 3.684 1.121 1.07 2.107 −4.3 0.0073127 protocadherin beta 14 C10orf11 3.112 3.302 2.409 −0.104 1.198 1.059 −4.299 0.0024548 chromosome 10 open reading frame 11 TRIP10 7.939 9.942 9.407 7.123 7.305 7.562 −4.295 0.0133662 thyroid hormone receptor interactor 10 CERCAM 7.344 6.666 7.925 5.113 5.687 5.244 −4.288 0.0028511 cerebral endothelial cell adhesion molecule PTPRG 4.405 5.999 6.32 4.189 3.563 3.899 −4.288 0.0166402 protein tyrosine phosphatase, receptor type, G PLBD1 4.948 4.313 5.437 1.366 4.043 2.848 −4.286 0.0132539 phospholipase B domain containing 1 LRP11 4.282 5.598 5.208 3.112 2.717 3.387 −4.273 0.0035322 low density lipoprotein receptor-related protein 11 TMEM163 5.834 6.216 5.55 3.455 3.508 4.282 −4.272 0.0011669 transmembrane protein 163 EMID1 2.98 2.879 3.404 1.407 0.515 0.886 −4.269 0.0009022 EMI domain containing 1 MMP2 10.857 9.629 11.636 8.036 8.767 8.876 −4.259 0.0059183 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) ZNF711 5.208 7.3 7.226 4.481 5.212 4.714 −4.253 0.0196752 zinc finger protein 711 SEC24D 6.301 8.552 8.18 5.964 6.1 6.302 −4.228 0.0323539 SEC24 family, member D (S. cerevisiae) FAIM2 3.27 2.163 3.914 1.366 1.033 1.201 −4.198 0.005816 Fas apoptotic inhibitory molecule 2 DLC1 6.641 8.215 6.182 4.113 4.897 4.76 −4.195 0.0037633 deleted in liver cancer 1 ECEL1 3.958 3.454 4.884 3.272 1.387 1.576 −4.192 0.0116026 endothelin converting enzyme-like 1 KCTD18 1.703 4.072 3.211 1.407 1.145 1.138 −4.188 0.0187587 potassium channel tetramerisation domain containing 18 TMEM189 5.992 8.531 7.116 5.567 4.402 5.057 −4.169 0.010357 transmembrane protein 189 GNG11 7.926 4.155 5.347 2.396 3.588 3.29 −4.162 0.0125435 guanine nucleotide binding protein (G protein), gamma 11 ASTN1 4.079 2.599 4.911 2.255 1.907 2.024 −4.157 0.016324 astrotactin 1 GABARAPL1 5.318 7.035 7.332 4.781 5.142 4.98 −4.157 0.0227717 GABA(A) receptor-associated protein like 1 SERPINA5 3.039 3.347 4.791 1.299 1.604 1.163 −4.135 0.0024354 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 KCNJ2 3.886 6.906 5.403 3.323 3.587 3.357 −4.13 0.0213093 potassium inwardly-rectifying channel, subfamily J, member 2 SLC17A7 4.943 2.849 4.809 2.466 2.899 2.667 −4.125 0.0335086 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 TMEM106B 3.971 5.846 5.353 3.529 2.727 3.315 −4.108 0.0102039 transmembrane protein 106B C20orf103 1.818 2.8 2.492 0.762 0.17 0.251 −4.106 0.0018674 chromosome 20 open reading frame 103 PTH1R 4.673 2.515 4.677 1.889 2.639 1.999 −4.106 0.0223517 parathyroid hormone 1 receptor ST6GAL2 3.259 5.47 5.023 3.433 2.763 2.976 −4.104 0.0349624 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 RNF122 4.682 3.799 4.634 1.715 2.601 2.663 −4.091 0.0024791 ring finger protein 122 CCDC136 5.328 6.809 6.704 4.607 4.777 4.184 −4.09 0.0084517 coiled-coil domain containing 136 HS1BP3 5.488 4.149 3.712 2.146 1.738 2.117 −4.088 0.0020348 HCLS1 binding protein 3 ELMO1 6.094 5.362 6.321 4.064 4.099 4.029 −4.087 0.0017543 engulfment and cell motility 1 ZEB1 6.955 4.923 6.444 4.195 4.691 4.415 −4.082 0.0180311 zinc finger E-box binding homeobox 1 FZD7 7.053 9.213 9.303 6.619 7.188 7.242 −4.069 0.0448158 frizzled homolog 7 (Drosophila) ADAM19 4.849 2.502 3.843 1.698 2.557 1.818 −4.068 0.0242577 ADAM metallopeptidase domain 19 ECSCR 6.553 1.846 3.45 1.426 1.305 1.715 −4.068 0.0327474 endothelial cell-specific chemotaxis regulator MPV17 4.064 6.118 5.329 3.228 3.992 3.305 −4.067 0.019844 MpV17 mitochondrial inner membrane protein PGCP 5.674 6.409 6.094 3.54 4.389 4.176 −4.057 0.0015898 No description KNDC1 3.025 0.924 2.647 0.86 0.515 0.631 −4.045 0.0291858 kinase non-catalytic C-lobe domain (KIND) containing 1 CLIC2 7.177 5.471 6.842 4.097 5.014 4.838 −4.011 0.0098805 chloride intracellular channel 2 NDRG3 3.966 4.282 3.839 1.837 2.728 1.837 −4.005 0.0020841 NDRG family member 3 ADD3 6.214 6.258 7.682 4.212 5.178 5.298 −4.005 0.0105445 adducin 3 (gamma) FMNL1 3.796 6.348 5.871 4.069 3.304 3.87 −4.003 0.0429227 formin-like 1 RAB6C 6.377 7.524 7.855 5.559 5.392 5.524 −3.998 0.0061859 RAB6C, member RAS oncogene family AADAT 2.242 2.822 3.187 1.188 0.609 0.552 −3.996 0.001896 aminoadipate aminotransferase RWDD2A 1.156 1.893 2.099 −0.104 −0.887 0.327 −3.993 0.0040288 RWD domain containing 2A SCN1B 2.911 5.637 4.321 2.323 2.486 2.111 −3.993 0.0160671 sodium channel, voltage-gated, type I, beta TMEM185A 5.328 5.719 4.834 3.332 3.561 3.271 −3.987 0.0013859 transmembrane protein 185A HEPH 6.017 7.928 8.153 5.515 5.983 5.934 −3.982 0.0313866 hephaestin KIAA0182 5.196 6.892 6.845 4.902 4.558 4.37 −3.973 0.0137318 KIAA0182 GNAI1 6.183 8.354 7.983 5.995 5.797 6.304 −3.968 0.0378286 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 ABLIM3 7.13 3.877 5.617 2.719 4.034 3.63 −3.963 0.0263955 actin binding LIM protein family, members ITGA5 10.794 8.697 9.51 7.04 7.94 7.524 −3.961 0.0063225 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) HDGFRP2 4.226 6.181 5.603 2.767 3.827 3.618 −3.961 0.0108857 No description AQP1 10.594 9.032 8.164 7.173 6.966 7.046 −3.96 0.0071789 aquaporin 1 (Colton blood group) FHL1 5.786 5.487 5.426 3.629 3.503 3.478 −3.956 0.0002654 four and a half LIM domains 1 CC2D1A 6.116 8.142 8.03 5.676 6.161 5.977 −3.95 0.034438 coiled-coil and C2 domain containing 1A IL1RAP 6.973 8.785 8.882 6.893 6.652 6.805 −3.944 0.0342277 interleukin 1 receptor accessory protein SHC4 3.71 6.207 4.953 2.852 3.176 2.977 −3.936 0.0134092 SHC (Src homology 2 domain containing) family, member 4 LOXL2 6.909 8.636 8.001 6.219 5.431 6.025 −3.935 0.0063848 lysyl oxidase-like 2 PCDHB13 2.258 2.074 2.039 0.173 0.283 −0.206 −3.932 0.0003785 protocadherin beta 13 IL11RA 5.698 6.829 6.234 3.738 4.261 4.478 −3.926 0.0018888 interleukin 11 receptor, alpha PALMD 5.29 5.17 3.439 2.14 3.319 3.079 −3.92 0.0178486 palmdelphin RETSAT 6.892 7.932 7.751 5.637 5.457 5.964 −3.913 0.0029985 retinol saturase (all-trans-retinol 13,14-reductase) SMPDL3A 3.56 3.072 5.089 0.762 3.121 2.124 −3.913 0.0281319 sphingomyelin phosphodiesterase, acid-like SA INPP5D 5.35 4.946 5.194 3.232 4.07 2.981 −3.897 0.0038191 inositol polyphosphate-5-phosphatase, 145kDa LYSMD4 2.711 5.178 4.899 2.33 2.578 3.217 −3.895 0.0476869 LysM, putative peptidoglycan-binding, domain containing 4 NID2 3.4 2.111 3.776 1.121 1.82 0.935 −3.879 0.0100787 nidogen 2 (osteonidogen) SOX11 6.201 7.296 6.3 5.185 4.247 4.815 −3.876 0.0046856 SRY (sex determining region Y)-box 11 SYNM 8.075 9.49 9.67 6.797 7.535 7.685 −3.876 0.0119296 synemin, intermediate filament protein AGR3 2.715 3.918 1.66 0.762 1.546 0.552 −3.872 0.0182421 anterior gradient homolog 3 (Xenopus laevis) OTUD1 5.905 6.561 5.462 4.172 3.957 3.865 −3.858 0.0017185 OTU domain containing 1 SOCS2 5.858 6.167 6.548 3.911 4.504 4.306 −3.855 0.0011455 suppressor of cytokine signaling 2 NBL1 8.422 8.421 10.308 7.619 6.477 7.816 −3.847 0.0239315 neuroblastoma, suppression of tumorigenicity 1 MBNL2 8.685 11.438 10.333 7.527 8.394 8.425 −3.834 0.0173707 muscleblind-like 2 (Drosophila) FABP7 1.571 4.038 0.788 −0.311 −0.887 −0.362 −3.818 0.0083745 fatty acid binding protein 7, brain IRX6 1.571 −0.258 1.852 −0.311 −0.887 −0.362 −3.818 0.0291085 iroquois homeobox 6 GPR116 7.73 4.573 5.157 2.642 3.841 3.872 −3.814 0.0166896 G protein-coupled receptor 116 BBS2 4.212 5.816 6.161 3.333 3.885 3.994 −3.814 0.0191622 Bardet-Biedl syndrome 2 PCDH18 4.934 5.636 5.944 3.134 3.825 3.706 −3.812 0.0023024 protocadherin 18 ETV1 6.254 8.288 7.115 4.325 5.62 5.264 −3.809 0.00782 ets variant 1 SNX7 4.389 5.886 5.417 3.489 3.444 3.787 −3.805 0.0085011 sorting nexin 7 CPS1 1.576 3.487 2.801 1.188 0.875 0.842 −3.801 0.0150447 carbamoyl-phosphate synthase 1, mitochondrial TRO 5.84 7.944 8.394 5.554 6.018 6.041 −3.799 0.048632 trophinin CREB5 7.11 10.08 8.893 6.863 6.968 6.989 −3.797 0.0336954 cAMP responsive element binding protein 5 C14orf132 3.869 6.034 6.055 4.13 3.968 3.481 −3.797 0.0483959 chromosome 14 open reading frame 132 C8orf40 3.766 4.538 3.827 1.757 2.206 2.614 −3.793 0.0027338 chromosome 8 open reading frame 40 CXCL13 1.714 1.75 1.674 0.173 −0.264 −0.206 −3.784 0.0005509 chemokine (C-X-C motif) ligand 13 ZNF385D 6.276 6.056 4.682 4.145 3.848 4.137 −3.783 0.0119224 zinc finger protein 385D CDON 4.156 4.334 4.386 2.238 2.794 2.311 −3.78 0.000787 Cdon homolog (mouse) RBP5 2.884 0.522 2.14 0.967 −0.104 −0.688 −3.777 0.0297324 retinol binding protein 5, cellular NTRK1 2.468 2.74 4.828 1.773 2.115 0.552 −3.773 0.0279051 neurotrophic tyrosine kinase, receptor, type 1 FERMT2 8.877 10.445 10.316 8.254 8.359 8.532 −3.767 0.0176497 fermitin family member 2 CCNG1 5.806 8.786 7.694 5.654 5.792 5.781 −3.765 0.0403835 cyclin G1 FGL2 7.309 4.707 6.168 4.021 4.448 4.258 −3.758 0.0207026 fibrinogen-like 2 C20orf199 9.8 11.308 10.845 8.937 8.615 9.297 −3.755 0.0089096 No description C1S 9.783 8.351 10.077 6.65 7.971 7.875 −3.751 0.0124626 complement component 1, s subcomponent PPAP2A 7.511 10.019 8.452 6.041 6.631 6.551 −3.735 0.0075839 phosphatidic acid phosphatase type 2A VATU 4.819 3.95 5.108 2.964 2.924 2.132 −3.721 0.0037097 vesicle amine transport protein 1 homolog (T. californica)-like MGST2 5.537 2.526 1.247 1.029 −0.648 0.831 −3.718 0.0220577 microsomal glutathione S-transferase 2 ABCA6 4.316 2.432 4.733 2.423 2.32 2.466 −3.715 0.0466473 ATP-binding cassette, sub-family A (ABC1), member 6 RPA3 2.607 4.26 3.196 0.924 2.332 1.305 −3.709 0.0125506 replication protein A3, 14kDa SORCS2 3.765 5.887 5.432 3.339 3.542 3.767 −3.705 0.0337326 sortilin-related VPS10 domain containing receptor 2 HVCN1 1.786 −0.529 1.548 −0.104 −0.887 −0.688 −3.705 0.0473714 hydrogen voltage-gated channel 1 SEPN1 7.244 7.574 7.637 5.688 5.389 5.729 −3.696 0.0005581 selenoprotein N, 1 GPR87 4.083 7.236 5.849 3.964 2.522 4.066 −3.693 0.0219375 G protein-coupled receptor 87 MAOB 5.725 7.508 5.531 4.465 3.647 4.504 −3.692 0.0091937 monoamine oxidase B PTN 7.593 9.666 8.759 6.875 6.864 6.982 −3.689 0.0126501 pleiotrophin NGFRAP1 8.008 9.794 9.7 6.564 7.725 7.913 −3.681 0.0200336 nerve growth factor receptor (TNFRSF16) associated protein 1 C3orf59 5.204 4.493 4.294 3.324 2.56 2.585 −3.68 0.0033119 chromosome 3 open reading frame 59 LCP1 10.817 8.26 8.661 7.29 6.381 6.91 −3.68 0.0079309 lymphocyte cytosolic protein 1 (L-plastin) CCDC82 4.456 6.379 5.895 3.93 3.876 4.499 −3.68 0.0286571 coiled-coil domain containing 82 POPDC2 6.424 7.197 7.817 4.546 5.884 5.518 −3.675 0.0092438 popeye domain containing 2 ADAMTS9 9.439 8.795 8.12 7.072 6.558 6.918 −3.673 0.0032389 ADAM metallopeptidase with thrombospondin type 1 motif, 9 HIBCH 6.351 7.911 8.105 5.367 6.223 6.038 −3.664 0.0216406 3-hydroxyisobutyryl-CoA hydrolase THBS4 6.104 4.49 4.929 2.543 4.231 3.197 −3.662 0.0147693 thrombospondin 4 KAZALD1 3.136 3.481 4.103 1.366 2.048 1.609 −3.66 0.0023238 Kazal-type serine peptidase inhibitor domain 1 CFH 7.197 5.063 6.622 4.75 4.639 4.839 −3.659 0.0261766 complement factor H LY6E 9.951 10.403 9.022 8.08 7.98 8.217 −3.658 0.0059326 lymphocyte antigen 6 complex, locus E 7-Mar 6.617 7.969 7.865 5.75 5.262 6.1 −3.654 0.0075081 membrane-associated ring finger (C3HC4) 7 AGA 2.419 3.953 2.802 0.762 2.115 0.552 −3.649 0.0117336 aspartylglucosaminidase HOXB3 5.166 2.631 4.164 2.304 1.932 2.986 −3.629 0.0418294 homeobox B3 PDS5B 5.793 7.111 7.288 5.183 4.842 5.429 −3.628 0.0135086 PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) AFAP1 6.261 7.941 7.269 5.411 5.186 5.459 −3.625 0.0068742 actin filament associated protein 1 CMC1 2.936 3.651 2.939 1.079 1.387 1.261 −3.623 0.0011018 COX assembly mitochondrial protein homolog (S. cerevisiae) SSPN 6.742 7.549 7.187 4.587 5.88 5.33 −3.622 0.0042091 sarcospan (Kras oncogene-associated gene) PCDHB5 3.715 3.911 3.881 2.026 2.166 1.779 −3.619 0.0004715 protocadherin beta 5 NAV1 6.65 7.441 6.002 5.126 4.425 4.8 −3.606 0.0044273 neuron navigator 1 KLHL5 3.822 4.284 3.249 1.723 2.439 1.766 −3.594 0.0037562 kelch-like 5 (Drosophila) GBP3 4.822 5.164 5.586 3.32 3.623 3.022 −3.591 0.0016499 guanylate binding protein 3 DLEU1 2.488 4.643 3.968 1.623 2.623 2.124 −3.59 0.0303069 deleted in lymphocytic leukemia 1 (non-protein coding) TST 1.48 2.902 2.463 1.672 −0.104 −0.362 −3.584 0.0183208 thiosulfate sulfurtransferase (rhodanese) EFR3A 4.503 5.989 5.902 3.877 3.524 4.151 −3.575 0.0129355 EFR3 homolog A (S. cerevisiae) FAT1 8.61 11.014 10.231 8.513 8.231 8.394 −3.572 0.0319067 FAT tumor suppressor homolog 1 (Drosophila) F2RL1 4.219 6.695 5.334 3.842 3.498 3.261 −3.57 0.0163519 coagulation factor II (thrombin) receptor-like 1 RBMS3 5.747 8.591 7.586 5.353 5.753 5.805 −3.563 0.0385362 RNA binding motif, single stranded interacting protein 3 TMEM135 3.055 4.281 4.185 2.246 2.45 2.091 −3.557 0.0082972 transmembrane protein 135 ZSCAN18 4.763 6.27 6.043 4.442 4.172 3.71 −3.55 0.014194 zinc finger and SCAN domain containing 18 SARDH 2.687 4.046 2.745 0.86 1.678 1.486 −3.547 0.0070459 sarcosine dehydrogenase NCRNA00087 1.62 3.332 1.062 0.173 −0.264 −0.206 −3.547 0.0083888 non-protein coding RNA 87 C7orf44 3.125 4.764 2.318 1.033 1.305 1.936 −3.531 0.0148337 chromosome 7 open reading frame 44 CTSO 6.535 6.192 6.386 4.209 5.068 4.573 −3.513 0.0020913 cathepsin O RAP2A 6.505 8.5 7.537 5.726 5.486 6.056 −3.507 0.0128497 RAP2A, member of RAS oncogene family ANK2 5.426 3.609 4.918 2.727 2.882 3.619 −3.499 0.0214574 ankyrin 2, neuronal FGF12 3.083 1.601 3.011 0.573 0.609 1.277 −3.496 0.0098447 fibroblast growth factor 12 HS3ST1 3.827 6.975 4.987 3.182 3.643 2.643 −3.495 0.0213272 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 LGALS3BP 8.428 6.888 8.019 5.952 6.33 6.218 −3.486 0.0106439 lectin, galactoside-binding, soluble, 3 binding protein ASPH 7.776 8.964 8.404 6.589 6.604 6.642 −3.483 0.003362 aspartate beta-hydroxylase PRSS23 6.451 6.84 6.046 4.127 4.661 5.041 −3.479 0.0029634 protease, serine, 23 ID4 6.091 9.385 7.404 5.288 5.61 5.938 −3.468 0.0267439 Description MST4 6.212 9.384 7.694 5.929 5.423 5.903 −3.462 0.0233777 No description FAM43A 7.006 7.363 5.864 4.983 5.216 5.326 −3.457 0.0114309 family with sequence similarity 43, member A SH3BGRL 7.653 9.124 8.936 6.553 7.232 7.148 −3.454 0.01347 SH3 domain binding glutamic acid-rich protein like IL3RA 5.049 3.928 2.281 1.525 2.291 2.141 −3.451 0.0302304 interleukin 3 receptor, alpha (low affinity) LOC729156 3.443 2.882 4.095 2.309 0.924 1.827 −3.45 0.0089647 No description C7orf60 3.621 5.725 5.177 3.391 3.363 3.489 −3.45 0.0354053 chromosome 7 open reading frame 60 TRIMS 4.614 5.55 5.484 2.994 3.767 3.086 −3.442 0.0027839 tripartite motif-containing 5 ARL6IP5 7.078 7.444 7.522 4.887 5.74 5.671 −3.44 0.0017057 ADP-ribosylation-like factor 6 interacting protein 5 HOPX 1.826 2.282 1.575 0.415 0.283 −0.206 −3.437 0.0024011 HOP homeobox F2R 4.843 3.808 6.084 2.454 3.404 3.064 −3.434 0.0132689 coagulation factor II (thrombin) receptor RAB15 7.285 8.959 8.932 7.179 6.205 6.602 −3.433 0.015303 RAB15, member RAS onocogene family TMEM59L 1.596 2.399 2.029 0.573 0.17 0.251 −3.43 0.0024934 transmembrane protein 59-like AKR7A2 4.245 5.551 4.557 2.4 3.469 3.773 −3.43 0.0189132 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) GLYATL2 2.06 3.16 3.48 0.924 0.283 2.493 −3.427 0.0321893 glycine-N-acyltransferase-like 2 LHFPL2 9.372 8.015 9.634 7.547 7.799 7.598 −3.421 0.0264971 lipoma HMGIC fusion partner-like 2 ITGB1BP1 4.09 3.92 4.579 3.141 2.146 2.235 −3.418 0.0049095 integrin beta 1 binding protein 1 FBLN5 6.866 6.049 8.513 4.276 5.66 5.675 −3.418 0.022009 fibulin 5 ESM1 7.362 3.517 2.053 1.556 2.04 1.747 −3.411 0.0448566 endothelial cell-specific molecule 1 PJA2 7.332 9.182 8.402 6.391 7.01 6.632 −3.41 0.0157845 praja ring finger 2 IL15RA 7.173 6.299 7.15 5.146 4.976 5.404 −3.409 0.0034049 interleukin 15 receptor, alpha MTERFD3 3.915 4.231 4.751 3.71 2.42 2.146 −3.407 0.0180024 MTERF domain containing 3 SH3KBP1 4.952 4.143 6.189 3.387 2.646 3.184 −3.405 0.0077713 SH3-domain kinase binding protein 1 NCDN 5.884 7.27 7.902 5.503 5.367 5.64 −3.403 0.0246505 neurochondrin ANKMY2 5.867 6.335 6.446 4.1 5.789 4.555 −3.403 0.026236 ankyrin repeat and MYND domain containing 2 PLEKHG1 6.172 5.092 5.049 3.283 3.875 3.636 −3.399 0.0039358 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 LOC389493 2.504 5.072 4.873 1.471 1.49 3.309 −3.394 0.0280997 No description PLXDC1 7.133 6.109 9.023 4.975 5.838 5.372 −3.39 0.0199735 plexin domain containing 1 DENND5A 7.893 9.52 9.305 7.548 7.472 7.546 −3.384 0.0248365 DENN/MADD domain containing 5A GIMAP2 2.618 0.978 3.244 0.86 0.515 1.244 −3.381 0.0485075 GTPase, IMAP family member 2 OAS1 2.329 0.701 2.169 0.573 0.17 0.251 −3.378 0.0259376 2′,5′-oligoadenylate synthetase 1, 40/46 kDa SECTM1 4.954 2.826 4.145 3.055 1.07 2.763 −3.378 0.0416642 secreted and transmembrane 1 CHRNE 5.606 6.828 6.215 4.485 4.068 4.459 −3.376 0.003123 cholinergic receptor, nicotinic, epsilon ZNF280D 3.495 4.161 4.299 2.406 2.406 2.167 −3.375 0.0026365 zinc finger protein 280D GPRC5B 4.826 3.823 2.909 1.999 2.298 2.071 −3.368 0.0115955 G protein-coupled receptor, family C, group 5, member B LRRTM2 2.782 4.624 4.307 2.46 2.556 2.828 −3.365 0.0435702 leucine rich repeat transmembrane neuronal 2 GALK2 2.841 4.967 4.573 2.301 2.592 3.217 −3.365 0.0463926 galactokinase 2 GXYLT2 2.584 4.104 4.292 2.354 2.497 1.486 −3.363 0.0249073 glucoside xylosyltransferase 2 PPFIA1 8.163 10.483 9.912 8.166 7.784 8.179 −3.356 0.0409094 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 HEXA 5.643 6.529 6.455 4.786 4.647 4.294 −3.348 0.0042162 hexosaminidase A (alpha polypeptide) SUCLG2 4.033 5.341 4.321 2.293 3.051 3.175 −3.34 0.0081205 succinate-CoA ligase, GDP-forming, beta subunit PAFAH1B3 3.044 4.517 2.917 1.623 1.305 1.277 −3.338 0.003993 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) TMEM130 2.947 3.871 5.49 1.299 2.132 2.348 −3.338 0.0111154 transmembrane protein 130 ANGPTL1 2.895 3.435 4.862 1.698 1.408 2.19 −3.334 0.0086972 angiopoietin-like 1 TMEM109 6.722 8.29 7.974 6.237 6.002 6.32 −3.332 0.0170502 transmembrane protein 109 VCAN 6.771 5.693 8.444 4.626 5.331 5.041 −3.317 0.0184453 versican SLC27A6 4.483 5.8 4.708 3.19 2.755 3.465 −3.313 0.0048644 solute carrier family 27 (fatty acid transporter), member 6 DEPDC6 3.742 4.967 5.191 3.373 2.686 3.239 −3.313 0.0151048 No description WASL 7.532 9.111 9.223 7.185 7.384 7.383 −3.313 0.0371711 Wiskott-Aldrich syndrome-like OLFM1 4.597 3.729 4.08 2.502 2.571 2.004 −3.306 0.0025764 olfactomedin 1 CCDC153 2.118 2.616 1.408 −0.311 1.198 0.327 −3.293 0.0148265 coiled-coil domain containing 153 DCX 2.697 4.361 5.478 2.642 2.377 2.824 −3.293 0.0459605 doublecortin KCTD17 3.377 3.368 3.662 2.005 1.374 1.66 −3.288 0.0011526 potassium channel tetramerisation domain containing 17 NEK7 6.453 7.858 7.698 5.862 5.643 6.144 −3.28 0.01652 NIMA (never in mitosis gene a)-related kinase 7 EMB 2.526 4.1 3.499 1.846 0.814 2.176 −3.275 0.013641 embigin GP1BB 2.021 1.699 1.148 −0.824 0.647 −0.012 −3.272 0.0096888 glycoprotein 1b (platelet), beta polypeptide LOX 4.809 4.147 5.062 2.995 3.352 3.002 −3.27 0.0045811 lysyl oxidase TBC1D1 6.584 5.64 4.819 4.204 3.799 3.933 −3.263 0.0105717 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 NMI 2.747 3.142 4.368 1.723 1.07 1.436 −3.261 0.0047328 N-myc (and STAT) interactor LOC1001909 6.28 6.391 6.363 5.545 4.579 4.579 −3.253 0.0078128 No description 39 EGR2 7.96 9.783 9.427 6.509 7.917 7.727 −3.247 0.0247349 early growth response 2 NXPH3 3.874 3.105 3.397 1.698 1.408 2.016 −3.246 0.0023381 neurexophilin 3 ARMCX1 5.305 6.286 6.542 4.57 4.542 4.843 −3.246 0.0135687 armadillo repeat containing, X-linked 1 LDHA 10.756 12.752 12.285 10.588 10.148 10.617 −3.244 0.0294863 lactate dehydrogenase A RBM7 6.056 7.82 7.372 5.48 5.675 5.803 −3.241 0.0241067 RNA binding motif protein 7 TWSG1 6.707 8.285 8.382 6.007 6.586 6.686 −3.24 0.0352071 twisted gastrulation homolog 1 (Drosophila) NR2F1 3.294 3.026 3.164 1.065 1.471 2.721 −3.233 0.0223002 nuclear receptor subfamily 2, group F, member 1 SLC25A46 3.626 4.474 3.856 2.781 1.873 2.575 −3.232 0.0068598 solute carrier family 25, member 46 DBI 6.083 8.884 7.38 5.689 5.267 6.003 −3.231 0.0281462 diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) SPARCL1 10.765 11.159 11.134 9.083 9.242 9.534 −3.207 0.0011311 SPARC-like 1 (hevin) CDKN1B 6.105 7.994 7.463 4.981 6.07 5.782 −3.206 0.0253087 cyclin-dependent kinase inhibitor 1 B (p27, Kip1) TP53INP1 4.239 4.329 4.601 2.565 2.56 3.214 −3.202 0.002678 tumor protein p53 inducible nuclear protein 1 CCBL2 3.682 6.13 5.097 3.427 3.168 3.52 −3.183 0.030538 cysteine conjugate-beta lyase 2 RFTN1 5.39 2.493 3.466 2.039 1.651 1.797 −3.181 0.0211991 raftlin, lipid raft linker 1 IFITM1 9.662 7.706 8.718 6.354 7.279 7.053 −3.171 0.0132139 interferon induced transmembrane protein 1 (9-27) C1orf61 5.306 6.926 5.741 4.076 4.271 4.062 −3.17 0.0058303 chromosome 1 open reading frame 61 CRYL1 2.785 1.931 3.254 1.121 0.814 1.334 −3.169 0.0090062 crystallin, lambda 1 GNG2 2.454 3.239 4.378 1.698 1.575 1.568 −3.168 0.0112327 guanine nucleotide binding protein (G protein), gamma 2 NUDT7 1.563 2.861 1.612 −0.104 1.198 0.327 −3.166 0.0204729 nudix (nucleoside diphosphate linked moiety X)- type motif 7 ZNF76 3.952 5.291 5.861 3.293 3.882 3.628 −3.166 0.0299513 zinc finger protein 76 (expressed in testis) PIR 3.319 2.853 3.483 0.86 2.008 1.66 −3.158 0.005059 pirin (iron-binding nuclear protein) FNDC3B 8.698 10.406 9.794 8.134 8.093 8.156 −3.158 0.0165751 fibronectin type III domain containing 3B GUCY1B3 3.565 3.727 4.374 2.132 1.907 2.187 −3.157 0.0016713 guanylate cyclase 1, soluble, beta 3 F8 4.532 3.478 2.36 1.478 1.82 1.999 −3.156 0.0185033 coagulation factor VIII, procoagulant component VASN 7.894 7.567 8.186 5.91 6.503 6.252 −3.154 0.0023553 vasorin CFI 6.01 6.904 6.183 4.132 5.248 4.785 −3.152 0.0074437 complement factor I EGFL6 1.826 0.78 3.047 0.173 0.283 −0.206 −3.144 0.0156564 EGF-like-domain, multiple 6 TCF19 2.061 3.573 2.494 0.573 0.875 0.842 −3.142 0.0040145 transcription factor 19 LOH3CR2A 3.845 2.33 3.26 1.494 1.873 1.609 −3.142 0.0141139 loss of heterozygosity, 3, chromosomal region 2, gene A TPT1 12.027 13.62 13.476 11.785 11.731 11.968 −3.142 0.0428239 tumor protein, translationally-controlled 1 KLRAQ1 2.68 4.738 4.441 3.087 1.959 2.409 −3.141 0.043304 KLRAQ motif containing 1 C1orf133 5.009 7.002 6.257 3.586 4.839 4.616 −3.12 0.0197875 chromosome 1 open reading frame 133 C4orf33 2.564 3.097 3.184 0.762 2.444 1.456 −3.119 0.0256479 chromosome 4 open reading frame 33 ERGIC1 6.572 7.146 6.583 5.205 4.899 5.505 −3.117 0.0035601 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 SFRP5 2.533 2.868 1.928 1.228 0.695 0.713 −3.117 0.005371 secreted frizzled-related protein 5 TP53I3 4.724 5.697 5.452 4.056 3.646 3.125 −3.117 0.0057065 tumor protein p53 inducible protein 3 JUN 11.939 13.854 13.365 10.857 11.98 11.725 −3.117 0.0303899 jun proto-oncogene MMP16 4.232 3.787 4.851 2.806 2.556 2.592 −3.116 0.0041225 matrix metallopeptidase 16 (membrane-inserted) GPR137C 3.31 4.069 3.518 2.358 1.575 2.43 −3.116 0.0075295 G protein-coupled receptor 137C DMXL2 2.047 3.296 2.988 1.366 1.033 1.348 −3.116 0.0088302 Dmx-like 2 ITM2C 5.257 7.414 6.399 4.811 4.237 4.764 −3.105 0.0160814 integral membrane protein 2C NEUROG2 2.667 4.901 3.345 1.033 2.612 2.026 −3.104 0.0285262 neurogenin 2 ABCD3 6.751 8.53 8.045 6.312 6.412 6.51 −3.103 0.0291357 ATP-binding cassette, sub-family D (ALD), member 3 C18orf1 3.37 5.439 4.743 3 3.109 3.264 −3.103 0.0364434 chromosome 18 open reading frame 1 LRP1 11.001 9.368 10.366 8.241 9.294 8.737 −3.092 0.022889 low density lipoprotein receptor-related protein 1 TSHZ1 6.317 5.338 6.214 4.32 4.69 4.358 −3.089 0.006794 teashirt zinc finger homeobox 1 DAB2 9.061 8.834 9.345 7.186 7.723 7.504 −3.079 0.0021893 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) TMEM176A 1.334 2.194 4.713 0.573 0.609 0.251 −3.078 0.0184038 transmembrane protein 176A C1GALT1C1 1.467 2.546 2.459 0.573 0.924 0.552 −3.077 0.0091343 C1GALT 1 -specific chaperone 1 ZNF92 2.983 4.632 3.099 2.999 1.362 1.999 −3.077 0.0442405 zinc finger protein 92 PIM1 5.28 5.316 6.131 3.42 4.511 4.454 −3.074 0.015635 pim-1 oncogene C20orf191 2.832 2.292 0.814 0.673 −0.012 0.831 −3.072 0.0333133 chromosome 20 open reading frame 191 HSPB2 5.194 6.896 6.067 4.448 4.716 4.446 −3.071 0.0159948 heat shock 27kDa protein 2 KIAA0528 2.859 4.317 4.632 2.008 3.014 2.391 −3.07 0.0305065 KIAA0528 CX3CL1 9.938 8.843 10.157 7.938 8.336 8.32 −3.069 0.013852 chemokine (C-X3-C motif) ligand 1 C19orf62 4.666 6.137 5.991 4.519 3.925 4.199 −3.069 0.0233906 chromosome 19 open reading frame 62 IGF1 7.7 6.852 8.763 5.628 6.31 6.083 −3.068 0.0119153 insulin-like growth factor 1 (somatomedin C) ART5 2.118 1.66 1.942 −0.104 0.886 0.327 −3.063 0.0054561 ADP-ribosyltransferase 5 TMEM14C 6.038 7.38 5.964 5.578 4.351 5.166 −3.059 0.0295185 transmembrane protein 14C LPCAT4 4.698 6.047 6.298 4.435 4.567 4.33 −3.058 0.0376712 lysophosphatidylcholine acyltransferase 4 MSX2P1 3.26 3.102 2.888 0.967 1.49 2.439 −3.057 0.0149517 msh homeobox 2 pseudogene 1 KERA 2.468 3.889 3.639 1.623 2.031 2.258 −3.05 0.0227288 keratocan PIK3R2 5.915 7.473 7.071 5.238 5.464 5.726 −3.048 0.025454 phosphoinositide-3-kinase, regulatory subunit 2 (beta) MLLT3 4.25 3.646 3.075 1.783 2.628 2.039 −3.045 0.0111512 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 HINT2 5.412 5.149 3.431 2.886 3.806 2.208 −3.044 0.0289898 histidine triad nucleotide binding protein 2 LDLRAD2 5.555 5.896 5.358 4.152 3.95 3.905 −3.043 0.0016427 low density lipoprotein receptor class A domain containing 2 GALC 4.944 4.543 4.664 2.937 3.558 3.015 −3.043 0.0030729 galactosylceramidase GNG5 7.681 9.097 9.072 7.491 6.921 7.2 −3.043 0.021295 guanine nucleotide binding protein (G protein), gamma 5 ATPIF1 6.45 8.718 7.859 6.097 6.254 6.507 −3.042 0.0453581 ATPase inhibitory factor 1 IGFBP4 10.82 10.293 10.443 8.689 9.083 9.132 −3.041 0.0025263 insulin-like growth factor binding protein 4 VGLL4 7.698 8.15 7.754 6.441 6.094 6.216 −3.039 0.0016041 vestigial like 4 (Drosophila) CDO1 3.77 4.41 4.55 2.593 2.242 2.947 −3.039 0.0038928 cysteine dioxygenase, type I TRPS1 6.904 8.633 8.208 6.55 6.814 6.605 −3.038 0.0389189 trichorhinophalangeal syndrome I RHOXF1 1.587 1.219 2.931 −0.824 1.341 −0.012 −3.029 0.0300057 Rhox homeobox family, member 1 COG4 4.202 5.586 5.285 3.463 3.686 3.881 −3.028 0.0198312 component of oligomeric golgi complex 4 SLC44A2 6.351 6.148 5.883 4.016 4.73 4.754 −3.026 0.003319 solute carrier family 44, member 2 ALDH7A1 7.415 9.105 8.361 5.895 6.866 6.765 −3.023 0.0108493 aldehyde dehydrogenase 7 family, member A1 MRGPRF 5.586 4.738 4.654 3.523 3.99 3.016 −3.023 0.0112885 MAS-related GPR, member F IFIT1 5.952 1.164 2.169 0.573 0.609 0.552 −3.023 0.0351807 interferon-induced protein with tetratricopeptide repeats 1 CLTCL1 1.818 2.167 2.492 0.573 0.609 0.552 −3.02 0.0020634 clathrin, heavy chain-like 1 LRRC17 1.826 1.753 3.757 0.924 0.695 0.162 −3.012 0.015112 leucine rich repeat containing 17 HSD17B11 7.647 4.123 5.66 3.082 4.069 4.123 −3.012 0.0325134 hydroxysteroid (17-beta) dehydrogenase 11 MAP3K12 3.211 4.579 5.232 2.853 3.221 2.99 −3.008 0.0438957 mitogen-activated protein kinase kinase kinase 12 SCARA3 5.564 5.743 4.483 3.9 3.975 4.019 −3.007 0.0189397 scavenger receptor class A, member 3 C4orf27 3.624 3.886 3.361 1.773 2.214 2.258 −3.005 0.0027552 chromosome 4 open reading frame 27 FAM69A 4.309 5.679 6.316 4.192 3.749 4.092 −3.004 0.0326136 family with sequence similarity 69, member A IDH2 4.077 6.173 4.531 2.492 3.52 3.441 -3 0.0195943 Description TSPAN6 5.589 4.818 5.326 3.743 3.427 3.869 −2.995 0.0036181 tetraspanin 6 RSPO1 1.374 1.753 2.911 0.173 0.695 −0.206 −2.99 0.0085727 R-spondin homolog (Xenopus laevis) HMGCL 2.691 3.24 3.633 1.471 1.66 1.878 −2.989 0.0051685 3-hydroxymethyl-3-methylglutaryl-CoA lyase PRKD1 2.539 4.102 4.243 2.667 1.709 2.295 −2.982 0.0352694 protein kinase D1 TESC 7.809 8.09 7.171 5.936 6.458 6.233 −2.98 0.0063776 tescalcin ITGA11 5.869 7.503 6.477 4.759 5.045 4.902 −2.98 0.008406 integrin, alpha 11 NDEL1 7.654 9.08 9.547 6.992 7.507 7.562 −2.974 0.0330285 nudE nuclear distribution gene E homolog (A. nidulans)-like 1 KIAA0652 6.144 7.407 7.971 5.156 6.117 5.836 −2.972 0.0289969 No description GOLM1 5.617 5.703 6.697 4.265 4.296 4.046 −2.97 0.0032904 golgi membrane protein 1 LRRC6 1.275 1.742 1.865 0.173 0.283 −0.206 −2.967 0.0031902 leucine rich repeat containing 6 LRRC8C 7.507 8.046 7.604 6.477 5.303 6.187 −2.967 0.0048287 leucine rich repeat containing 8 family, member C BRP44 5.815 8.137 6.68 5.09 5.111 5.49 −2.967 0.0242842 brain protein 44 KIAA1755 4.804 5.854 6.379 4.171 4.81 4.253 −2.967 0.0346949 KIAA1755 ADRA2A 3.355 2.12 2.612 0.573 2.41 0.552 −2.966 0.0369922 adrenergic, alpha-2A-, receptor LGALS3 8.713 10.243 9.889 8.332 7.577 8.323 −2.962 0.0169028 lectin, galactoside-binding, soluble, 3 MORC3 6.39 6.909 7.509 5.344 5.339 5.768 −2.959 0.0090699 MORC family CW-type zinc finger 3 TENC1 6.72 6.5 7.664 4.935 5.903 5.6 −2.959 0.0144995 tensin like C1 domain containing phosphatase (tensin 2) SURF1 3.816 4.905 5.108 3.063 3.341 3.365 −2.957 0.0172626 surfeit 1 LOC1002718 2.792 1.699 1.847 −1.775 0.647 1.228 −2.957 0.0236074 No description 31 TBX5 2.136 0.817 2.827 0.573 0.609 0.251 −2.955 0.0297396 T-box 5 MYOM2 1.976 3.111 3.548 0.415 1.616 1.576 −2.951 0.016799 myomesin (M-protein) 2, 165kDa C20orf30 7.182 6.867 6.324 4.764 5.316 5.363 −2.948 0.0040073 chromosome 20 open reading frame 30 TNFRSF19 3.017 4.248 2.993 1.659 1.434 1.886 −2.947 0.00565 tumor necrosis factor receptor superfamily, member 19 CLEC12A 2.132 2.899 3.039 −0.824 1.341 1.908 −2.944 0.0265651 C-type lectin domain family 12. member A INMT 3.649 2.518 4.516 1.065 2.674 2.094 −2.939 0.0319139 indolethylamine N-methyltransferase SENP7 3.968 4.882 5.052 2.414 2.731 3.698 −2.937 0.0103999 SUMO1/sentrin specific peptidase 7 RARRES2 6.411 5.784 8.121 4.232 5.682 5.68 −2.932 0.0490749 retinoic acid receptor responder (tazarotene induced) 2 TRMT5 8.091 8.792 8.15 6.335 6.998 7.24 −2.931 0.0080597 TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae) TBC1D5 6.35 6.626 6.353 4.073 5.212 4.804 −2.925 0.0036467 TBC1 domain family, members RIPK2 6.737 8.191 8.227 6.008 6.679 6.428 −2.925 0.0300379 receptor-interacting serine-threonine kinase 2 ATG7 6.759 6.798 6.659 5.25 4.665 5.229 −2.924 0.0014767 ATG7 autophagy related 7 homolog (S. cerevisiae) BNIP3L 6.039 8.947 7.243 5.584 5.695 5.854 −2.924 0.0364163 BCL2/adenovirus E1B 19kDa interacting protein 3- like WIPF1 4.719 3.549 5.692 2.43 3.41 3.174 −2.919 0.0237676 WAS/WASL interacting protein family, member 1 SCP2 5.287 6.495 4.931 3.743 4.191 3.671 −2.916 0.0094126 sterol carrier protein 2 C3orf14 4.622 5.118 3.874 3.126 2.492 3.083 −2.906 0.0072004 chromosome 3 open reading frame 14 SLC35E2 5.157 6.212 6.737 4.407 5.199 4.564 −2.905 0.0326064 solute carrier family 35, member E2 SPHAR 3.979 5.724 4.687 3.076 3.303 3.149 −2.904 0.0123811 S-phase response (cyclin related) PCMTD2 4.385 5.725 5.875 3.986 4.337 3.952 −2.903 0.0358961 protein-L-isoaspartate (D-aspartate) O- methyltransferase domain containing 2 ACTA1 2.461 3.613 3.169 0.924 1.332 2.735 −2.903 0.0379488 actin, alpha 1, skeletal muscle TBC1D19 1.556 2.108 2.511 0.573 0.609 0.552 −2.898 0.0051342 TBC1 domain family, member 19 OXCT1 4.291 5.981 5.258 4.039 2.755 3.901 −2.898 0.0218731 3-oxoacid CoA transferase 1 LCA5 5.033 7.46 6.268 4.149 4.764 4.733 −2.897 0.024154 Leber congenital amaurosis 5 UTRN 6.424 7.118 6.923 5.006 5.585 5.366 −2.895 0.0044688 utrophin PITPNC1 6.058 4.281 5.017 3.597 3.484 2.856 −2.893 0.0097174 phosphatidylinositol transfer protein, cytoplasmic 1 BAT5 4.74 5.995 5.406 3.875 3.617 3.993 −2.89 0.0076562 No description FBXW4 5.338 6.896 6.701 4.921 5.17 5.177 −2.889 0.0387823 F-box and WD repeat domain containing 4 FZD10 4.66 5.231 5.625 3.131 3.934 4.029 −2.886 0.0109609 frizzled homolog 10 (Drosophila) NTRK2 8.592 9.51 8.308 6.997 7.08 7.064 −2.885 0.0038857 neurotrophic tyrosine kinase, receptor, type 2 RHOBTB1 3.244 2.876 4.154 1.715 1.456 2.609 −2.885 0.018235 Rho-related BTB domain containing 1 SIPA1L2 6.506 7.176 6.1 4.933 4.98 5.007 −2.88 0.0042377 signal-induced proliferation-associated 1 like 2 B3GNT1 5.124 6.349 6.028 3.71 4.824 4.352 −2.879 0.0142491 UDP-GlcNAc:betaGal beta-1,3-N- acetylglucosaminyltransferase 1 GPC6 4.535 5.72 5.328 4.194 3.111 3.428 −2.878 0.0105373 glypican 6 CXCL14 11.658 12.71 12.232 10.2 11.025 10.708 −2.875 0.0079667 chemokine (C-X-C motif) ligand 14 ENTPD1 6.14 5.445 5.934 4.256 4.413 4.52 −2.869 0.0039143 ectonucleoside triphosphate diphosphohydrolase 1 GCH1 7.381 8.752 9.121 6.795 7.233 7.494 −2.866 0.0475746 GTP cyclohydrolase 1 SYNJ2 6.6 7.685 7.271 6.167 5.646 5.621 −2.864 0.0122651 synaptojanin 2 GMNN 3.095 5.915 4.441 1.949 2.928 3.311 −2.854 0.0385433 geminin, DNA replication inhibitor MAF 7.693 8.55 8.619 5.887 7.129 7.038 −2.853 0.0121972 v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) CREB3L2 7.3 8.051 8.276 6.541 6.471 6.577 −2.849 0.0092295 cAMP responsive element binding protein 3-like 2 TMEM9 6.922 7.155 6.907 5.41 5.398 5.97 −2.847 0.0040502 transmembrane protein 9 NCOA7 8.848 10.197 9.573 7.381 8.128 8.064 −2.846 0.0080454 nuclear receptor coactivator 7 TPM1 10.137 12.285 10.993 9.485 9.319 9.815 −2.845 0.0229491 tropomyosin 1 (alpha) HSDL2 4.61 4.055 5.452 3.944 2.687 3.086 −2.844 0.0228962 hydroxysteroid dehydrogenase like 2 GAPDH 10.2 11.614 11.388 9.865 9.881 10.011 −2.842 0.0390499 glyceraldehyde-3-phosphate dehydrogenase LIPA 6.686 6.268 5.92 5.193 4.417 4.697 −2.834 0.0057337 lipase A, lysosomal acid, cholesterol esterase STX18 3.677 5.208 5.076 3.705 2.861 3.47 −2.834 0.0367819 syntaxin 18 DNASE1L3 4.915 1.19 1.826 −0.311 0.886 0.327 −2.83 0.0262803 deoxyribonuclease l-like 3 PSAP 10.913 11.179 11.459 9.643 9.679 9.72 −2.827 0.0019847 prosaposin CGNL1 5.14 4.909 5.13 3.28 3.63 3.86 −2.827 0.0027481 cingulin-like 1 GLCE 2.311 4.446 2.709 2.546 0.814 1.334 −2.822 0.0450705 glucuronic acid epimerase ZNF354B 4.03 5.188 5.485 3.692 3.794 3.007 −2.821 0.0230336 zinc finger protein 354B TAPT1 6.479 7.129 7.31 5.633 5.427 5.715 −2.82 0.0066352 transmembrane anterior posterior transformation 1 PNPLA8 6.628 8.105 7.921 6.161 6.22 6.61 −2.819 0.0372104 patatin-like phospholipase domain containing 8 STS 4.162 3.243 4.508 2.875 2.344 2.669 −2.814 0.0175839 steroid sulfatase (microsomal), isozyme S ITGA1 5.215 6.285 5.256 4.455 3.723 4.197 −2.811 0.0120011 integrin, alpha 1 ANGPTL2 8.351 6.77 6.876 5.484 5.713 5.279 −2.81 0.007327 angiopoietin-like 2 IMMP2L 3.923 5.544 5.35 2.659 4.054 3.841 −2.809 0.041501 IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) UBA3 4.979 6.908 6.107 4.618 3.721 4.948 −2.807 0.0277284 ubiquitin-like modifier activating enzyme 3 FAM43B 4.295 2.593 2.763 1.672 1.49 1.107 −2.801 0.0100715 family with sequence similarity 43, member B ZCCHC24 7.115 7.321 7.103 5.836 5.254 5.675 −2.8 0.0018459 zinc finger, CCHC domain containing 24 ANGPT1 2.949 4.624 3.614 2.101 2.129 2.962 −2.799 0.0360907 angiopoietin 1 PAPSS1 7.044 8.393 8.085 6.318 6.623 6.601 −2.797 0.019492 3′-phosphoadenosine 5′-phosphosulfate synthase 1 PNRC2 8.843 9.261 9.749 7.36 8.047 8.12 −2.796 0.0095714 proline-rich nuclear receptor coactivator 2 IFFO2 10.409 12.327 11.687 10.164 10.252 10.205 −2.794 0.0440567 intermediate filament family orphan 2 BTG2 8.408 9.517 9.645 7.249 8.164 7.704 −2.792 0.0156278 BTG family, member 2 ACVR1 6.081 7.765 7.237 6.157 5.006 5.757 −2.79 0.0353223 activin A receptor, type I SSC5D 6.589 4.989 5.915 3.509 5.358 4.316 −2.79 0.0451513 No description LIMCH1 6.693 6.778 6.825 4.903 5.646 5.3 −2.786 0.0035036 LIM and calponin homology domains 1 MAD2L1 1.037 2.313 2.557 1.079 0.283 0.162 −2.786 0.0234242 MAD2 mitotic arrest deficient-like 1 (yeast) UBAC1 4.531 6.143 5.344 4.245 3.867 3.493 −2.785 0.0192774 UBA domain containing 1 LRRC32 7.736 3.703 4.676 2.226 3.483 3.318 −2.783 0.0304994 leucine rich repeat containing 32 AUH 3.905 4.424 4.433 2.949 2.289 3.195 −2.778 0.0077506 AU RNA binding protein/enoyl-CoA hydratase FBXL4 2.165 3.755 3.736 1.864 1.269 2.283 −2.773 0.0331251 F-box and leucine-rich repeat protein 4 C1R 10.629 9.351 10.643 8.311 9.172 8.786 −2.772 0.018969 complement component 1, r subcomponent TRAPPC2P1 4.33 5.041 4.71 3.571 3.196 3.119 −2.771 0.0055377 trafficking protein particle complex 2 pseudogene 1 RHOB 12.248 11.165 12.347 10.24 10.777 10.818 −2.771 0.0208049 ras homolog gene family, member B BMPR1A 4.93 6.228 6.262 4.531 4.357 4.792 −2.771 0.0301109 bone morphogenetic protein receptor, type IA DIP2C 5.682 6.917 6.555 5.085 5.298 4.956 −2.77 0.019135 DIP2 disco-interacting protein 2 homolog C (Drosophila) ASTN2 5.565 7.144 6.526 5.057 4.983 5.062 −2.77 0.0200537 astrotactin 2 PPP2R5B 5.874 8.047 6.957 5.487 5.574 5.193 −2.769 0.0266309 protein phosphatase 2, regulatory subunit B′, beta SLC35A1 3.415 3.856 3.997 2.136 2.528 2.254 −2.768 0.0036739 solute carrier family 35 (CMP-sialic acid transporter), member A1 STX12 6.774 8.097 7.658 6.189 5.466 6.278 −2.767 0.0130607 syntaxin 12 UBC 6.684 6.154 5.197 4.687 4.294 4.939 −2.766 0.0217915 ubiquitin C IDH1 4.042 4.411 3.938 1.741 2.575 3.083 −2.763 0.0067525 Description LPAR1 6.355 5.279 6.299 4.849 4.833 4.826 −2.763 0.0260049 lysophosphatidic acid receptor 1 DENND3 5.547 3.715 4.678 2.986 3.286 3.212 −2.761 0.0205201 DENN/MADD domain containing 3 LCP2 5.37 2.898 2.922 1.659 1.434 2.228 −2.76 0.0206225 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) CTSH 6.3 5.993 4.971 4.07 4.532 4.808 −2.752 0.0265901 cathepsin H SEP12 1.936 3.043 2.492 1.623 0.17 1.033 −2.75 0.0166753 septin 12 PDE2A 4.109 3.644 3.414 2.083 2.249 2.187 −2.746 0.0025406 phosphodiesterase 2A, cGMP-stimulated RALGPS2 4.106 5.248 5.556 3.975 3.7 3.791 −2.746 0.0404701 Ral GEF with PH domain and SH3 binding motif 2 POLD4 6.401 6.346 5.68 4.894 4.501 4.925 −2.737 0.0070051 polymerase (DNA-directed), delta 4 ROPN1 1.44 3.763 1.715 0.323 0.988 −0.012 −2.735 0.0201223 ropporin, rhophilin associated protein 1 EXTL2 3.326 4.58 4.241 3.122 2.643 2.79 −2.733 0.0273807 exostoses (multiple)-like 2 PLOD1 7.003 7.03 6.366 5.029 5.555 5.578 −2.728 0.0065822 procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1 FAM101A 4.261 4.358 3.303 2.157 2.853 2.813 −2.727 0.0160263 family with sequence similarity 101, member A IPO8 5.429 6.223 5.958 4.607 4.122 4.511 −2.726 0.0054769 importin 8 LETMD1 4.677 5.986 6.755 3.516 4.54 4.539 −2.725 0.0276626 LETM1 domain containing 1 BDH2 5.163 6.227 6.128 4.394 4.783 4.61 −2.722 0.0187458 3-hydroxybutyrate dehydrogenase, type 2 APBB2 6.475 5.415 6.089 4.645 4.854 4.464 −2.721 0.0115175 amyloid beta (A4) precursor protein-binding, family B, member 2 CD46 7.677 8.754 8.966 6.846 7.312 7.349 −2.717 0.0225821 CD46 molecule, complement regulatory protein UBA7 6.191 5.088 6.435 3.682 4.994 4.709 −2.715 0.0273235 ubiquitin-like modifier activating enzyme 7 SFT2D2 2.657 2.875 1.721 1.121 0.814 1.436 −2.712 0.0193217 SFT2 domain containing 2 HLA-DQA1 7.054 1.842 2.363 1.623 0.924 0.552 −2.711 0.0405573 major histocompatibility complex, class II, DQ alpha 1 RTN1 4.447 5.393 4.511 3.315 3.217 3.009 −2.71 0.0045382 reticulon 1 TSPAN13 7.535 7.78 7.152 5.715 5.919 6.457 −2.709 0.0058017 tetraspanin 13 HIF1A 8.234 7.913 7.107 6.682 6.446 6.475 −2.709 0.0190284 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) TTC7B 4.146 5.112 5.43 3.812 3.543 3.675 −2.709 0.0244258 tetratricopeptide repeat domain 7B RCBTB2 3.487 4.702 4.732 3.294 2.932 3.254 −2.709 0.0367024 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 ALG5 4.392 4.24 3.462 2.955 2.304 2.434 −2.707 0.0084797 asparagine-linked glycosylation 5, dolichyl- phosphate beta-glucosyltransferase homolog (S. cerevisiae) GHDC 5.75 4.022 4.639 2.585 4.012 3.455 −2.707 0.0358718 GH3 domain containing KDR 7.26 3.682 3.604 2.246 3.536 2.242 −2.705 0.0427967 kinase insert domain receptor (a type III receptor tyrosine kinase) TMEM44 4.725 4.108 5.04 3.074 3.605 3.204 −2.704 0.0110639 transmembrane protein 44 TF 5.411 6.071 7.299 3.977 5.41 5.033 −2.702 0.0420298 transferrin PPIC 5.162 5.095 4.518 3.528 3.586 3.728 −2.701 0.0058897 peptidylprolyl isomerase C (cyclophilin C) ZNF516 5.769 7.161 6.8 5.368 5.346 5.536 −2.698 0.0343221 zinc finger protein 516 ZNF577 3.238 3.938 4.713 3.176 2.509 2.406 −2.694 0.032585 zinc finger protein 577 ZNF521 5.307 6.148 6.588 4.481 4.721 4.812 −2.689 0.015851 zinc finger protein 521 FNDC1 5.132 4.555 4.589 3.802 2.721 3.168 −2.678 0.0075767 fibronectin type III domain containing 1 RBKS 2.504 2.528 1.033 −0.104 −0.104 1.107 −2.678 0.0165822 ribokinase DEGS2 2.495 3.975 2.29 0.924 1.616 1.075 −2.676 0.0126429 degenerative spermatocyte homolog 2, lipid desaturase (Drosophila) PICALM 9.361 10.823 10.356 8.937 8.716 9.022 −2.674 0.0242985 phosphatidylinositol binding clathrin assembly protein CCPG1 5.585 6.226 5.707 4.169 4.57 4.488 −2.668 0.0044616 cell cycle progression 1 CDH1 10.24 11.49 10.715 9.129 9.299 9.351 −2.668 0.0071546 cadherin 1, type 1, E-cadherin (epithelial) CTSF 8.941 7.595 8.095 6.181 7.235 7.09 −2.665 0.0258911 cathepsin F STAT3 9.039 9.912 10.024 8.511 8.452 8.499 −2.663 0.0189569 signal transducer and activator of transcription 3 (acute-phase response factor) LOC644538 2.403 2.074 2.731 0.173 2.07 0.992 −2.658 0.0395013 No description TCEAL3 2.975 3.779 4.313 1.898 2.142 2.904 −2.655 0.0235165 transcription elongation factor A (SII)-like 3 AIP 4.65 5.427 7.027 4.145 3.906 4.018 −2.655 0.023548 aryl hydrocarbon receptor interacting protein PLA2G7 2.039 4.339 2.166 1.407 1.145 0.631 −2.654 0.0236374 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) CYB5R3 7.93 7.792 7.173 6.232 5.958 6.523 −2.651 0.007126 cytochrome b5 reductase 3 VIPAR 3.28 3.164 4.157 1.757 2.497 2.31 −2.65 0.0154933 VPS33B interacting protein, apical-basolateral polarity regulator FAT3 2.111 2.972 3.157 1.698 1.408 1.568 −2.647 0.0199392 FAT tumor suppressor homolog 3 (Drosophila) FAM188A 3.34 4.385 4.808 3 1.936 3.25 −2.646 0.0288753 family with sequence similarity 188, member A PIK3CA 5.581 6.731 7.019 5.616 5.167 5.238 −2.645 0.0492967 phosphoinositide-3-kinase, catalytic, alpha polypeptide DNAH1 3.246 4.628 3.713 2.163 2.311 2.916 −2.644 0.0193983 dynein, axonemal, heavy chain 1 EPB41L4B 3.428 5.511 4.234 2.832 2.7 3.247 −2.642 0.0315218 erythrocyte membrane protein band 4.1 like 4B ABCA1 5.97 5.437 6.342 4.547 4.569 4.694 −2.64 0.0085204 ATP-binding cassette, sub-family A (ABC1), member 1 AZIN1 8.145 9.04 8.82 7.481 7.31 7.419 −2.639 0.0106561 antizyme inhibitor 1 SLC25A30 5.177 7.325 6.015 4.911 3.78 4.614 −2.639 0.0210102 solute carrier family 25, member 30 PTGIS 4.885 2.415 3.608 2.214 1.976 2.242 −2.628 0.0403549 prostaglandin 12 (prostacyclin) synthase ADAMTS1 8.755 11.314 9.907 7.811 8.696 8.513 −2.627 0.0337877 ADAM metallopeptidase with thrombospondin type 1 motif, 1 ITPR1 6.842 9.636 7.911 5.919 6.52 6.53 −2.624 0.0276483 inositol 1,4,5-triphosphate receptor, type 1 BMP2K 4.776 6.105 6.012 4.714 4.461 4.144 −2.624 0.0365136 BMP2 inducible kinase KCNJ8 3.38 1.858 2.668 0.573 1.305 1.277 −2.622 0.0132833 potassium inwardly-rectifying channel, subfamily J, member 8 ZNF792 4.2 0.82 1.674 0.173 0.283 0.478 −2.622 0.0366416 zinc finger protein 792 NAGK 5.856 7.386 6.864 5.808 5.342 5.474 −2.621 0.0424984 N-acetylglucosamine kinase TBC1D4 9.008 10.004 10.538 7.974 9.015 8.614 −2.619 0.034702 TBC1 domain family, member 4 ASAH1 5.255 6.911 5.287 3.869 4.298 3.973 −2.614 0.0104364 N-acylsphingosine amidohydrolase (acid ceramidase) 1 ARHGAP6 3.461 2.662 3.869 1.942 2.483 1.966 −2.614 0.0266116 Rho GTPase activating protein 6 IGSF1 1.077 2.204 1.936 0.573 0.17 0.552 −2.611 0.0157416 immunoglobulin superfamily, member 1 RHOQ 8.689 9.507 9.698 7.884 8.19 8.123 −2.61 0.0161651 ras homolog gene family, member Q SDCBP 8.233 7.502 7.278 6.473 5.894 6.408 −2.609 0.0096573 syndecan binding protein (syntenin) FAM8A1 6.676 6.973 6.258 4.874 5.484 5.585 −2.609 0.0104507 family with sequence similarity 8, member A1 CNPY4 5.491 5.103 5.671 3.717 4.605 4.108 −2.609 0.0123524 canopy 4 homolog (zebrafish) PLD1 5.361 5.919 5.905 3.883 5.269 4.521 −2.609 0.0362395 phospholipase D1, phosphatidylcholine-specific CIC 7.857 9.305 8.424 6.836 7.049 7.042 −2.606 0.0099485 capicua homolog (Drosophila) SGK223 7.016 7.384 6.355 5.36 5.696 5.636 −2.603 0.0102468 No description BASP1 9.616 9.332 8.695 7.248 8.631 7.951 −2.603 0.0313458 brain abundant, membrane attached signal protein 1 FBXL5 4.152 5.618 5.169 4.17 3.55 3.791 −2.599 0.0450047 F-box and leucine-rich repeat protein 5 GAN 5.687 7.28 6.945 5.567 4.717 5.649 −2.598 0.0376247 gigaxonin PPM1M 5.293 4.663 5.394 3.287 4.396 3.77 −2.597 0.0187794 protein phosphatase, Mg2+/Mn2+ dependent, 1M AMACR 1.684 2.539 2.819 1.121 1.362 1.163 −2.596 0.0268248 alpha-methylacyl-CoA racemase SCCPDH 3.168 1.408 2.307 1.299 0.814 0.935 −2.588 0.0370137 saccharopine dehydrogenase (putative) DOCK1 6.09 6.519 5.9 5.147 4.432 5.029 −2.587 0.0102325 dedicator of cytokinesis 1 PDP1 5.901 6.759 7.341 5.253 5.677 5.389 −2.586 0.0293647 pyruvate dehyrogenase phosphatase catalytic subunit 1 ALDH1A1 3.079 3.046 4.864 2.008 1.989 1.676 −2.585 0.0129813 aldehyde dehydrogenase 1 family, member A1 NCEH1 5.32 7.494 6.433 5.229 4.785 5.063 −2.585 0.0406876 neutral cholesterol ester hydrolase 1 NCAPG2 2.196 3.193 3.72 1.875 1.562 1.824 −2.584 0.0269342 non-SMC condensin II complex, subunit G2 PFKFB2 7.349 9.472 8.384 6.702 7.225 7.015 −2.582 0.0360979 6-phosphofructo-2-kinase/fructose-2,6- biphosphatase 2 HMGN3 7.143 7.812 7.792 5.775 6.582 6.345 −2.581 0.0108278 high mobility group nucleosomal binding domain 3 CYP27A1 5.94 7.54 6.166 4.649 4.801 5.032 −2.576 0.0094784 cytochrome P450, family 27, subfamily A, polypeptide 1 LMBRD1 3.122 2.436 3.946 1.757 2.025 1.66 −2.576 0.0205817 LMBR1 domain containing 1 EIF2S3 7.385 8.64 8.6 7.276 6.963 7.075 −2.574 0.0419439 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa SERPINE1 10.169 9.738 11.025 8.656 8.811 9.153 −2.563 0.0126916 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 MTIF3 3.336 3.693 3.973 2.219 3.066 1.98 −2.56 0.020596 mitochondrial translational initiation factor 3 EFHC2 2.171 3.438 2.633 2.064 0.814 1.436 −2.56 0.0319546 EF-hand domain (C-terminal) containing 2 TUBA1A 9.844 10.547 9.199 7.926 8.489 8.671 −2.558 0.0131359 tubulin, alpha 1a PLA2G4A 3.568 5.356 3.896 2.488 2.543 2.546 −2.556 0.0105516 phospholipase A2, group IVA (cytosolic, calcium- dependent) RUNX1T1 3.296 3.344 4.731 1.942 2.401 2.798 −2.556 0.0250998 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) PARVA 7.062 8.142 7.833 6.479 6.475 6.48 −2.555 0.0180096 parvin, alpha AGAP3 8.374 8.499 8.907 7.274 7.132 7.147 −2.553 0.0030586 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 KLHL13 6.696 8.868 6.821 5.838 5.344 6.006 −2.553 0.0228225 kelch-like 13 (Drosophila) HIBADH 3.289 5.374 4.095 2.742 2.418 2.936 −2.553 0.0243178 3-hydroxyisobutyrate dehydrogenase HEPACAM 3.107 2.491 1.589 1.407 0.515 1.138 −2.553 0.0259784 hepatocyte cell adhesion molecule SERPING1 9.026 9.284 9.092 7.49 7.934 7.759 −2.549 0.0025835 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 LOC441204 0.726 1.923 1.88 0.573 0.17 0.251 −2.549 0.0306876 No description C9orf46 3.899 4.896 4.191 3.695 2.313 2.841 −2.548 0.023842 chromosome 9 open reading frame 46 BZW2 7.279 8.163 8.018 6.814 6.243 6.559 −2.547 0.013402 basic leucine zipper and W2 domains 2 HEYL 3.829 2.37 3.066 1.366 2.481 1.201 −2.545 0.0312928 hairy/enhancer-of-split related with YRPW motif- like KRT14 16.031 16.031 15.235 14.495 14.684 14.684 −2.544 0.0166609 keratin 14 C10orf32 6.702 5.905 6.774 5.318 5.304 5.427 −2.544 0.0199199 chromosome 10 open reading frame 32 NTAN1 5.57 4.461 4.084 2.807 4.167 3.114 −2.544 0.0413265 N-terminal asparagine amidase FSCN1 9.141 9.316 8.342 7.22 7.944 7.794 −2.543 0.0179888 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus) DTX4 5.583 4.916 6.225 4.236 4.3 4.002 −2.542 0.0133734 deltex homolog 4 (Drosophila) RORA 7.021 6.846 7.328 5.467 6.108 5.676 −2.541 0.0068012 RAR-related orphan receptor A C11orf74 1.774 2.857 1.976 1.407 0.515 0.631 −2.54 0.0193146 chromosome 11 open reading frame 74 TMEM65 5.862 6.459 6.298 5.115 4.707 4.922 −2.538 0.0064062 transmembrane protein 65 EXOC1 3.273 4.396 4.366 2.454 2.604 3.052 −2.538 0.0197804 exocyst complex component 1 ENHO 1.556 1.513 2.132 0.573 0.17 0.251 −2.537 0.0049353 energy homeostasis associated CYB5D2 5.612 4.004 4.957 3.127 4.164 3.615 −2.536 0.048416 cytochrome b5 domain containing 2 PGM2L1 5.955 7.117 7.207 5.429 5.869 5.424 −2.528 0.0324748 phosphoglucomutase 2-like 1 ZMYM5 5.086 6.083 6.327 4.126 4.989 4.608 −2.527 0.0287165 zinc finger, MYM-type 5 SLC22A4 5.006 5.723 4.619 4.155 4.021 3.282 −2.526 0.021682 solute carrier family 22 (organic cation/ergothioneine transporter), member 4 RWDD3 2.078 3.906 2.97 1.44 1.633 1.878 −2.526 0.0329427 RWD domain containing 3 GJA1 12.062 12.134 12.358 10.695 10.972 11.021 −2.525 0.0036109 gap junction protein, alpha 1, 43kDa MAP6 2.028 2.769 3.341 1.299 1.82 1.436 −2.52 0.0290806 microtubule-associated protein 6 NFIA 7.748 9.127 8.041 6.415 6.891 7.149 −2.519 0.0153681 nuclear factor l/A ABCG1 7.47 7.47 6.872 5.542 6.304 5.826 −2.513 0.0082829 ATP-binding cassette, sub-family G (WHITE), member 1 SPATA7 2.601 3.254 3.441 1.121 2.242 1.928 −2.507 0.0189912 spermatogenesis associated 7 PCDHB10 3.645 4.619 4.277 2.803 3.294 2.807 −2.505 0.0180382 protocadherin beta 10 EPB41L2 6.463 7.397 7.547 5.786 6.11 6.072 −2.505 0.0261551 erythrocyte membrane protein band 4.1-like 2 FNDC5 2.932 2.053 3.325 1.065 1.608 1.628 −2.503 0.0188166 fibronectin type III domain containing 5 SLC2A12 4.482 6.594 5.383 3.605 4.07 4.059 −2.503 0.0234507 solute carrier family 2 (facilitated glucose transporter), member 12 MTMR11 5.586 7.063 6.233 4.383 5.649 4.91 −2.502 0.0381019 myotubularin related protein 11 PIGF 4.182 4.952 4.859 3.537 3.548 3.423 −2.501 0.0132396 phosphatidylinositol glycan anchor biosynthesis, class F LPAR6 6.05 8.59 7.193 5.525 5.87 5.881 −2.501 0.0409301 lysophosphatidic acid receptor 6 MAGT1 6.478 7.697 6.583 5.703 5.156 5.689 −2.499 0.0160957 magnesium transporter 1 WNT4 4.059 3.068 3.452 2.616 2.565 1.747 −2.499 0.0260707 wingless-type MMTV integration site family, member 4 FAM149A 2.654 1.489 1.658 0.762 0.17 0.552 −2.494 0.0123596 family with sequence similarity 149, member A VIT 4.248 3.813 5.789 2.495 3.618 3.368 −2.494 0.0402132 vitrin RGL1 6.124 6.046 7.185 4.538 5.867 5.377 −2.494 0.049545 ral guanine nucleotide dissociation stimulator-like 1 JUB 6.272 7.384 7.151 5.834 6.01 5.6 −2.492 0.0292151 jub, ajuba homolog (Xenopus laevis) MRC2 9.266 9.547 9.684 7.807 8.371 8.23 −2.491 0.0047614 mannose receptor, C type 2 CYBRD1 8.793 7.933 8.379 6.624 7.062 7.078 −2.491 0.0061787 cytochrome b reductase 1 SIDT2 6.705 7.744 7.729 5.558 6.432 6.061 −2.483 0.0172698 SID1 transmembrane family, member 2 ANXA6 7.259 7.453 7.136 5.658 6.141 6.136 −2.482 0.0048859 annexin A6 SCARB2 7.507 8.462 7.893 6.581 6.523 6.733 −2.482 0.0086242 scavenger receptor class B, member 2 GULP1 4.13 4.866 5.381 3.566 2.819 4.053 −2.482 0.0308035 GULP, engulfment adaptor PTB domain containing 1 MPP5 6.519 7.041 7.742 5.73 5.708 5.836 −2.481 0.0133462 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) GSTK1 7.713 8.635 8.032 6.402 7.179 6.943 −2.481 0.0160406 glutathione S-transferase kappa 1 FAM162A 6.397 7.754 7.01 5.699 5.658 5.969 −2.481 0.0211619 family with sequence similarity 162, member A TNFSF13B 2.005 2.097 1.978 0.924 0.695 −0.206 −2.479 0.0062524 tumor necrosis factor (ligand) superfamily, member 13b B2M 13.204 12.625 13.58 11.859 11.894 11.962 −2.479 0.0123954 beta-2-microglobulin SHISA5 7.564 7.488 6.739 6.172 5.703 6.254 −2.479 0.0160886 shisa homolog 5 (Xenopus laevis) CSRP1 13.263 13.476 13.123 11.816 12.129 12.07 −2.475 0.0038334 cysteine and glycine-rich protein 1 MEIS2 6.385 5.613 5.845 4.364 4.94 4.537 −2.475 0.0089848 Meis homeobox 2 MAT1A 1.513 2.812 2.548 0.692 1.506 1.075 −2.473 0.0357874 methionine adenosyltransferase l, alpha SEP8 6.427 7.524 7.692 5.884 6.386 6.101 −2.473 0.0440638 septin 8 HLCS 2.958 3.967 3.675 2.661 2.225 2.203 −2.471 0.0215461 holocarboxylase synthetase (biotin-(proprionyl-CoA- carboxylase (ATP-hydrolysing)) ligase) RCAN1 11.185 10.02 9.741 8.436 9.256 9.43 −2.471 0.0387336 regulator of calcineurin 1 RNF38 5.823 7.31 6.739 5.436 4.679 5.67 −2.468 0.0283315 ring finger protein 38 SLCO2A1 5.967 7.888 6.89 5.728 5.196 5.588 −2.466 0.0301989 solute carrier organic anion transporter family, member 2A1 CRLF1 4.818 5.754 3.618 3.517 3.581 2.717 −2.464 0.0382979 cytokine receptor-like factor 1 ARMCX3 7.024 8.233 8.037 6.209 6.765 6.736 −2.463 0.0299013 armadillo repeat containing, X-linked 3 FGF1 4.234 6.715 5.141 3.615 4.197 3.841 −2.463 0.0453509 fibroblast growth factor 1 (acidic) ZNF304 5.072 5.822 5.619 4.512 4.218 4.32 −2.461 0.0131216 zinc finger protein 304 FIGNL2 2.856 1.095 1.931 0.86 0.515 0.631 −2.461 0.0340066 fidgetin-like 2 CCDC50 8.239 9.229 8.821 7.529 7.109 7.522 −2.46 0.0095285 coiled-coil domain containing 50 TAC1 4.745 3.63 6.28 2.573 3.448 3.737 −2.458 0.0422337 tachykinin, precursor 1 SPRED2 7.05 8.234 8.116 6.324 6.819 6.905 −2.456 0.0391429 sprouty-related, EVH1 domain containing 2 CHST11 5.923 6.841 6.918 5.46 4.891 5.622 −2.455 0.0225478 carbohydrate (chondroitin 4) sulfotransferase 11 TTC37 2.728 4.11 3.586 2.311 1.434 2.608 −2.453 0.0299299 tetratricopeptide repeat domain 37 GPC4 3.219 4.574 4.341 3.046 2.685 3.115 −2.453 0.0463855 glypican 4 PLAU 8.166 8.351 8.744 7.087 7.056 6.896 −2.452 0.0033763 plasminogen activator, urokinase EMILIN1 8.259 8.623 8.449 7.155 7.233 7.06 −2.451 0.0030514 elastin microfibril interfacer 1 HOMER1 6.682 7.738 7.631 5.875 6.341 6.339 −2.448 0.0263469 homer homolog 1 (Drosophila) ZNF331 6.938 7.991 7.527 5.305 6.7 6.277 −2.447 0.0243936 zinc finger protein 331 CDH26 2.525 3.009 2.659 1.556 1.235 1.386 −2.446 0.0039286 cadherin 26 ZNF642 1.46 1.766 2.606 1.033 0.17 0.842 −2.446 0.0254969 zinc finger protein 642 JDP2 3.765 3.923 3.583 2.333 2.294 2.746 −2.443 0.0046355 Jun dimerization protein 2 FZD1 8.781 8.943 9.61 7.494 8.173 7.715 −2.44 0.0118738 frizzled homolog 1 (Drosophila) GBP1 7.472 8.359 9.002 6.408 7.328 7.072 −2.44 0.0295113 guanylate binding protein 1, interferon-inducible, 67kDa RAP2B 8.566 9.624 9.641 8.133 8.354 8.28 −2.44 0.0430071 RAP2B, member of RAS oncogene family NUCB2 6.661 5.967 5.655 4.682 4.599 5.023 −2.438 0.0116448 nucleobindin 2 PLS3 7.967 9.147 8.123 7.114 6.681 7.346 −2.438 0.0170859 plastin 3 MBD5 3.098 3.695 4.7 2.325 2.735 2.411 −2.435 0.0251807 methyl-CpG binding domain protein 5 VPS8 2.591 4.704 3.554 2.339 2.136 2.274 −2.428 0.0393804 vacuolar protein sorting 8 homolog (S. cerevisiae) PDK3 3.371 4.32 3.693 2.2 2.587 2.415 −2.425 0.0079738 pyruvate dehydrogenase kinase, isozyme 3 FOXJ3 7.379 8.424 8.671 7.146 6.987 7.242 −2.425 0.0494026 forkhead box J3 IFT88 2.422 2.16 3.289 1.065 1.145 1.864 −2.424 0.0243421 intraflagellar transport 88 homolog (Chlamydomonas) EGLN1 7.099 6.481 7.269 5.435 5.785 5.992 −2.423 0.014365 egl nine homolog 1 (C. elegans) ZNF410 5.373 6.614 5.392 4.931 4.097 4.741 −2.422 0.0386807 zinc finger protein 410 TBC1D2B 4.973 4.234 5.593 3.667 3.7 3.82 −2.416 0.0262288 TBC1 domain family, member 2B PIK3C2G 3.438 4.73 4.383 3.111 2.894 3.236 −2.416 0.0378093 phosphoinositide-3-kinase, class 2, gamma polypeptide KIAA0922 6.393 7.538 7.501 5.92 5.818 6.266 −2.415 0.0329606 KIAA0922 NBEAL1 2.337 3.355 2.797 1.494 2.048 1.525 −2.414 0.0253516 neurobeachin-like 1 CCNDBP1 4.771 5.972 5.5 4.422 4.217 4.229 −2.413 0.0283866 cyclin D-type binding-protein 1 ACP6 2.16 2.885 2.016 0.924 1.616 0.478 −2.411 0.0188452 acid phosphatase 6, lysophosphatidic CEP170 6.059 7.848 6.773 5.27 5.503 5.543 −2.411 0.0215318 centrosomal protein 170kDa C3orf64 7.24 8.398 8.051 6.783 6.77 6.791 −2.408 0.0276311 chromosome 3 open reading frame 64 ANKRD36 1.424 2.952 2.674 0.692 0.283 1.685 −2.406 0.0315561 ankyrin repeat domain 36 FAM115C 1.818 3.14 3.176 2.09 1.305 0.552 −2.405 0.0384646 family with sequence similarity 115, member C ROR2 3.91 4.274 4.624 2.258 3.359 3.076 −2.404 0.0144924 receptor tyrosine kinase-like orphan receptor 2 KAT2B 4.115 4.644 5.396 3.23 3.956 3.381 −2.4 0.0318502 K(lysine) acetyltransferase 2B ZNF672 5.776 6.018 6.783 5.469 4.514 5.198 −2.398 0.0369636 zinc finger protein 672 SYCE1 3.41 2.215 1.89 1.065 1.88 0.631 −2.393 0.0421464 synaptonemal complex central element protein 1 PHF21A 5.457 6.46 6.527 4.54 5.27 5.116 −2.39 0.0313723 PHD finger protein 21A KIF21B 3.125 4.336 4.009 2.752 2.879 2.585 −2.39 0.0355985 kinesin family member 21B GPR146 5.18 1.998 1.538 0.924 0.283 1.305 −2.387 0.0415211 G protein-coupled receptor 146 NDN 6.387 6.224 6.651 5.705 5.134 4.897 −2.384 0.0146841 necdin homolog (mouse) ITGBL1 4.471 6.374 4.077 2.884 3.356 3.219 −2.382 0.0180625 integrin, beta-like 1 (with EGF-like repeat domains) MAN2B2 6.704 5.531 5.952 4.535 4.766 4.701 −2.381 0.0107233 mannosidase, alpha, class 2B, member 2 ALKBH3 1.62 1.966 1.946 1.079 0.695 0.162 −2.38 0.0150376 alkB, alkylation repair homolog 3 (E. coli) TBC1D23 6.405 7.417 7.596 6.187 5.714 6.166 −2.38 0.0365672 TBC1 domain family, member 23 UBQLN2 7.488 9.051 8.546 7.296 6.92 7.316 −2.379 0.040543 ubiquilin 2 C2orf28 5.333 6.476 5.669 4.036 4.431 5.226 −2.377 0.0328318 chromosome 2 open reading frame 28 SLC27A3 6.379 6.227 6.164 5.131 4.701 4.978 −2.376 0.0033834 solute carrier family 27 (fatty acid transporter), member 3 SIK3 8.627 9.391 9.519 8.149 8.143 8.113 −2.376 0.0255656 SIK family kinase 3 GABARAP 8.161 8.866 7.215 6.285 6.913 7.076 −2.376 0.0331323 GABA(A) receptor-associated protein PDHB 4.785 5.782 5.151 4.534 3.507 4.415 −2.376 0.0469364 pyruvate dehydrogenase (lipoamide) beta PDLIM3 8.734 10.385 8.793 7.513 7.546 7.858 −2.375 0.0134163 PDZ and LIM domain 3 ABLIM1 8.739 9.975 9.323 8.064 8.075 8.221 −2.375 0.0202261 actin binding LIM protein 1 YAF2 8.189 10.196 9.306 8.062 7.271 8.215 −2.369 0.0431681 YY1 associated factor 2 TIFA 5.316 6.122 6.124 4.609 4.882 4.789 −2.365 0.0212134 TRAF-interacting protein with forkhead-associated domain MOSC2 3.024 2.567 3.162 1.623 1.92 1.513 −2.364 0.0082185 MOCO sulphurase C-terminal domain containing 2 PAPSS2 4.755 4.181 5.701 2.94 3.722 3.527 −2.364 0.0178164 3′-phosphoadenosine 5′-phosphosulfate synthase 2 TPM4 10.212 11.147 10.641 9.891 8.971 9.835 −2.363 0.0386993 tropomyosin 4 CNTN3 2.463 4.33 3.5 2.539 1.587 2.26 −2.362 0.0466402 contactin 3 (plasmacytoma associated) SH3BP5 7.925 9.783 8.074 6.686 7.58 7.426 −2.36 0.0463633 SH3-domain binding protein 5 (BTK-associated) ARL15 3.483 4.611 3.986 2.749 2.339 3.157 −2.358 0.0209337 ADP-ribosylation factor-like 15 SAMD9 3.375 1.275 2.17 1.121 0.814 0.935 −2.354 0.0457323 sterile alpha motif domain containing 9 C3orf18 3.55 4.168 4.028 1.723 3.217 2.796 −2.349 0.0253588 chromosome 3 open reading frame 18 TTYH3 5.438 7.724 6.307 5.108 4.485 5.074 −2.349 0.0281391 tweety homolog 3 (Drosophila) TPST1 6.564 7.676 7.314 5.334 6.403 6.202 −2.347 0.0356128 tyrosylprotein sulfotransferase 1 C14orf179 4.713 5.651 5.154 3.924 4.118 3.879 −2.346 0.0142613 chromosome 14 open reading frame 179 CD74 9.6 8.856 8.016 7.094 7.67 7.627 −2.345 0.0246984 CD74 molecule, major histocompatibility complex, class II invariant chain ST3GAL6 1.861 2.508 0.96 0.86 0.515 0.631 −2.345 0.0484732 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 RFXAP 3.084 3.381 3.733 1.612 2.507 2.153 −2.342 0.0119868 regulatory factor X-associated protein DOCK4 5.146 5.811 5.624 4.207 4.585 4.198 −2.339 0.0106804 dedicator of cytokinesis 4 EXOC4 4.518 5.024 5.034 3.658 4.042 3.292 −2.339 0.0140531 exocyst complex component 4 PIGK 5.782 6.325 6.223 4.088 5.137 4.999 −2.336 0.0131072 phosphatidylinositol glycan anchor biosynthesis, class K TPK1 1.896 0.96 1.747 0.173 −0.264 0.713 −2.336 0.0182278 thiamin pyrophosphokinase 1 WDFY3 6.495 7.209 7.657 6.054 5.978 5.987 −2.333 0.0271568 WD repeat and FYVE domain containing 3 WLS 7.594 9.338 8.521 7.299 7.419 7.096 −2.333 0.0426608 wntless homolog (Drosophila) PNRC1 11.007 11.621 13.033 9.789 10.813 10.849 −2.327 0.0468777 proline-rich nuclear receptor coactivator 1 FYN 7.244 7.817 7.859 6.588 6.449 6.641 −2.325 0.0141339 FYN oncogene related to SRC, FGR, YES ALX4 2.295 2.296 2.864 1.648 1.033 1.609 −2.324 0.0236911 ALX homeobox 4 EPB41L4A 4.168 5.041 4.572 3.277 2.954 3.834 −2.321 0.0192631 erythrocyte membrane protein band 4.1 like 4A TRAPPC2L 3.877 4.579 5.971 3.379 2.681 3.365 −2.32 0.0203642 trafficking protein particle complex 2-like HNRNPD 8.767 9.51 9.808 8.4 8.224 8.296 −2.32 0.0298254 heterogeneous nuclear ribonucleoprotein D (AU- rich element RNA binding protein 1,37kDa) BMPR2 8.834 8.283 7.648 6.728 7.352 7.071 −2.318 0.024941 bone morphogenetic protein receptor, type II (serine/threonine kinase) FBXO42 5.483 7.227 6.247 5.085 4.682 5.034 −2.318 0.0259054 F-box protein 42 ARHGEF3 5.584 5.407 4.894 3.483 4.634 4.194 −2.318 0.0271095 Rho guanine nucleotide exchange factor (GEF) 3 TGFBR3 8.42 8.618 9.619 7.207 7.95 7.924 −2.318 0.0340631 transforming growth factor, beta receptor III GGN 2.687 2.436 2.06 1.272 0.848 1.244 −2.317 0.0075696 gametogenetin GSTZ1 4.179 5.216 4.357 2.967 3.351 3.513 −2.315 0.0153288 glutathione transferase zeta 1 SKIV2L 4.231 5.068 5.123 3.912 3.446 3.663 −2.315 0.0224991 superkiller viralicidic activity 2-like (S. cerevisiae) C5 2.419 3.241 3.303 0.573 2.031 2.124 −2.314 0.0301917 complement component 5 LPL 3.986 3.794 4.286 3.058 3.076 1.948 −2.313 0.017591 lipoprotein lipase SERPINB6 7.26 6.667 6.651 5.442 5.818 5.61 −2.311 0.0087508 serpin peptidase inhibitor, clade B (ovalbumin), member 6 NUDT4P1 8.297 8.94 9.228 7.097 7.892 7.731 −2.311 0.0193482 nudix (nucleoside diphosphate linked moiety X)- type motif 4 pseudogene 1 ST3GAL3 4.062 4.344 4.9 2.855 3.486 3.5 −2.309 0.0215733 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 FAM124A 2.241 2.963 1.332 1.333 0.17 1.033 −2.309 0.0391779 family with sequence similarity 124A CTSB 10.174 9.535 8.81 8.028 8.547 8.329 −2.308 0.0295886 cathepsin B CUL1 7.203 8.139 8.989 6.933 6.917 6.972 −2.307 0.0493582 cullin 1 SPATA6 3.263 4.838 4.857 2.555 2.423 3.653 −2.303 0.0372963 spermatogenesis associated 6 ANP32A 5.144 5.584 4.99 3.935 4.193 3.941 −2.302 0.0075438 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A NRIP1 7.821 8.512 8.6 6.886 7.114 7.401 −2.297 0.0161172 nuclear receptor interacting protein 1 COL4A2 10.156 11.255 9.757 9.172 8.749 8.957 −2.295 0.0175367 collagen, type IV, alpha 2 ACP5 4.948 4.347 5.19 3.149 4.101 3.649 −2.294 0.023719 acid phosphatase 5, tartrate resistant MEOX1 5.583 2.268 2.056 1.121 1.07 0.935 −2.294 0.0263046 mesenchyme homeobox 1 HECW1 2.393 2.533 2.012 2.019 0.814 0.935 −2.294 0.0476404 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 SYNGR1 5.318 5.425 5.368 4.242 3.973 4.172 −2.291 0.0027982 synaptogyrin 1 ATXN1 7.753 8.637 8.395 7.028 7.2 7.249 −2.291 0.0194512 ataxin 1 FDXR 2.693 3.084 3.743 1.818 2.548 1.779 −2.29 0.0344645 ferredoxin reductase COL18A1 10.12 10.687 10.483 9.288 9.405 9.18 −2.289 0.0090377 collagen, type XVIII, alpha 1 C17orf72 4.037 2.689 2.58 1.854 1.787 1.386 −2.289 0.0199463 chromosome 17 open reading frame 72 TBC1D15 7.257 8.742 7.94 6.746 6.61 7.101 −2.289 0.0394892 TBC1 domain family, member 15 PPT2 6.445 6.384 6.523 5.329 5.264 5.084 −2.288 0.00302 palmitoyl-protein thioesterase 2 CPOX 3.461 4.382 3.927 2.891 2.733 2.279 −2.288 0.0132904 coproporphyrinogen oxidase UBR7 6.135 7.606 6.31 5.76 4.942 5.412 −2.287 0.0321049 ubiquitin protein ligase E3 component n-recognin 7 (putative) KHDRBS1 9.3 9.863 9.859 8.695 8.096 8.669 −2.282 0.0140316 KH domain containing, RNA binding, signal transduction associated 1 C7orf70 3.543 4.402 4.111 3.581 2.352 2.886 −2.282 0.0484589 chromosome 7 open reading frame 70 DZIP1 4.865 6.258 5.93 4.744 4.769 4.229 −2.276 0.0483237 DAZ interacting protein 1 LRRC16A 6.03 6.219 6.454 5.053 5.033 5.004 −2.274 0.0044759 leucine rich repeat containing 16A DCHS1 8.108 7.061 7.493 6.116 6.688 6.309 −2.272 0.0219518 dachsous 1 (Drosophila) SCRN3 1.353 2.108 2.084 0.762 0.924 0.251 −2.271 0.0177277 secernin 3 TPD52 4.933 6.196 5.583 4.4 4.593 4.388 −2.271 0.0320906 tumor protein D52 CYB5R4 1.767 2.54 2.118 1.299 0.814 0.935 −2.27 0.0173049 cytochrome b5 reductase 4 TDRD6 1.858 3.308 2.739 1.556 1.235 1.747 −2.27 0.04391 tudor domain containing 6 SLC31A2 4.488 3.739 4.367 2.974 3.306 2.686 −2.268 0.0149038 solute carrier family 31 (copper transporters), member 2 KDELC1 3.063 3.624 3.67 2.494 2.309 1.956 −2.26 0.0117214 KDEL (Lys-Asp-Glu-Leu) containing 1 IFIT2 3.46 2.111 1.908 1.121 0.814 0.935 −2.259 0.0148966 interferon-induced protein with tetratricopeptide repeats 2 3-Mar 4.878 5.49 4.938 4.099 3.703 4.09 −2.258 0.0135544 membrane-associated ring finger (C3HC4) 3 LOC550643 6.403 6.504 5.797 5.31 5.125 5.229 −2.258 0.0212757 No description TLE4 7.619 8.998 8.243 6.504 7.226 7.069 −2.255 0.0212063 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) PON2 5.557 7.364 6.245 5.074 5.048 5.176 −2.251 0.0356271 paraoxonase 2 ATP11C 5.917 6.508 6.604 5.436 4.854 5.289 −2.247 0.016774 ATPase, class VI, type 11C STARD8 4.443 3.829 3.187 2.953 2.019 2.727 −2.247 0.0298684 StAR-related lipid transfer (START) domain containing 8 AGXT2L2 5.601 5.424 6.447 4.632 4.434 4.43 −2.246 0.0115561 alanine-glyoxylate aminotransferase 2-like 2 BDNFOS 2.836 3.119 2.533 1.366 2.348 1.609 −2.246 0.0340559 No description PNMA1 7.883 8.184 7.925 6.361 7.141 6.758 −2.244 0.0094927 paraneoplastic antigen MA1 YPEL2 6.467 6.03 6.238 4.296 5.402 5.072 −2.243 0.0139329 yippee-like 2 (Drosophila) TGM2 5.629 3.723 3.144 2.557 2.396 2.909 −2.243 0.041242 transglutaminase 2 (C polypeptide, protein- glutamine-gamma-glutamyltransferase) RAPGEF2 8.084 8.845 9.044 7.68 7.526 7.746 −2.242 0.0333348 Rap guanine nucleotide exchange factor (GEF) 2 HEY1 9.025 6.476 5.896 4.738 5.831 5.311 −2.242 0.0426293 hairy/enhancer-of-split related with YRPW motif 1 TNIP1 7.27 7.897 8.466 6.565 6.733 6.87 −2.241 0.0256064 TNFAIP3 interacting protein 1 PRTFDC1 4.249 4.478 5.095 2.876 4.037 3.315 −2.239 0.0303756 phosphoribosyl transferase domain containing 1 CSNK1G3 5.966 6.859 6.68 5.51 5.54 5.519 −2.235 0.0320977 casein kinase 1, gamma 3 ABHD14A 4.808 4.323 5.042 3.421 3.883 3.613 −2.232 0.0184181 abhydrolase domain containing 14A ADH5 6.736 7.902 7.398 5.96 6.24 6.368 −2.232 0.0257523 alcohol dehydrogenase 5 (class III), chi polypeptide VPS45 2.722 3.404 3.896 2.409 2.245 1.818 −2.232 0.0265043 vacuolar protein sorting 45 homolog (S. cerevisiae) LAMB1 7.839 7.244 9.301 6.193 7.242 6.68 −2.232 0.0429527 laminin, beta 1 PIBF1 2.986 2.32 2.748 1.679 1.287 1.59 −2.231 0.0114975 progesterone immunomodulatory binding factor 1 PECI 5.832 7.246 6.289 5.245 4.689 5.133 −2.229 0.016158 peroxisomal D3,D2-enoyl-CoA isomerase PGAP3 4.98 4.507 3.93 3.352 3.642 3.219 −2.227 0.0304228 post-GPI attachment to proteins 3 SMARCA1 6.889 7.434 7.484 6.224 6.33 6.173 −2.226 0.0165 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 C1QTNF3 4.121 3.467 3.68 2.274 2.966 2.747 −2.226 0.0212399 C1q and tumor necrosis factor related protein 3 SELE 5.958 4.33 4.059 2.905 3.438 3.28 −2.226 0.0220355 selectin E ZC4H2 2.805 3.354 3.453 1.494 2.449 2.2 −2.226 0.024433 zinc finger, C4H2 domain containing ASMTL 4.312 5.307 4.49 3.634 3.157 3.964 −2.226 0.0337025 acetylserotonin O-methyltransferase-like DLG2 2.851 2.977 2.804 1.698 1.408 2.19 −2.223 0.0149903 discs, large homolog 2 (Drosophila) SNTB1 3.449 3.131 3.243 2.351 1.85 2.091 −2.222 0.0073485 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) SEP6 5.267 4.854 5.105 3.702 4.241 3.921 −2.222 0.0111784 septin 6 BCL2 5.817 6.544 6.566 5.045 5.415 5.374 −2.22 0.0261623 B-cell CLL/lymphoma 2 RASSF1 8.07 8.316 8.756 7.356 7.058 7.167 −2.218 0.0099006 Ras association (RalGDS/AF-6) domain family member 1 HAUS8 4.12 4.91 3.804 3.613 2.97 2.715 −2.218 0.0325263 HAUS augmin-like complex, subunit 8 PCCA 3.938 4.293 4.289 3.14 2.662 3.271 −2.217 0.0115762 propionyl CoA carboxylase, alpha polypeptide NAALAD2 1.107 2.072 2.052 0.573 0.924 0.251 −2.216 0.027214 N-acetylated alpha-linked acidic dipeptidase 2 WTAP 9.619 9.497 9.69 8.375 8.349 8.751 −2.215 0.0076075 Wilms tumor 1 associated protein SEMA6A 5.611 5.313 6.391 4.464 4.924 4.417 −2.214 0.0245103 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A DDX42 7.271 8.158 8.177 6.644 6.88 7.033 −2.211 0.035464 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 NIPSNAP1 4.452 5.476 4.638 3.308 3.809 3.908 −2.21 0.0242699 nipsnap homolog 1 (C. elegans) CNIH3 2.821 1.944 2.657 0.86 1.678 0.886 −2.208 0.0157344 cornichon homolog 3 (Drosophila) BAI2 4.824 5.435 5.06 4.434 3.917 3.651 −2.208 0.0214395 brain-specific angiogenesis inhibitor 2 ABCD4 5.095 6.201 5.329 4.616 3.954 4.288 −2.206 0.0208321 ATP-binding cassette, sub-family D (ALD), member 4 SKAP2 5.101 5.588 4.891 3.708 4.447 4.291 −2.206 0.0295443 src kinase associated phosphoprotein 2 RAC2 3.081 3.66 2.657 1.606 1.88 2.52 −2.204 0.0339994 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) C1orf226 5.627 6.864 6.644 5.022 5.725 5.169 −2.202 0.0496129 chromosome 1 open reading frame 226 TTC31 2.356 1.982 2.844 1.757 0.848 0.886 −2.196 0.0228647 tetratricopeptide repeat domain 31 CD180 0.871 1.715 1.747 0.924 −0.264 −0.206 −2.196 0.028929 CD180 molecule RB1CC1 8.082 8.919 8.863 7.57 7.717 7.786 −2.193 0.0404972 RB1-inducible coiled-coil 1 ARHGAP24 6.861 4.779 5.763 4.652 4.632 4.112 −2.191 0.0451728 Rho GTPase activating protein 24 COMMD3 3.451 4.48 4.012 2.402 3.35 2.591 −2.189 0.0290957 COMM domain containing 3 ANK3 3.562 4.269 4.51 3.139 2.882 3.312 −2.189 0.0359169 ankyrin 3, node of Ranvier (ankyrin G) GDF10 3.655 1.095 1.99 0.86 0.515 0.886 −2.188 0.0458689 growth differentiation factor 10 ACTR8 4.431 4.826 4.872 3.557 3.744 3.351 −2.186 0.0084303 ARP8 actin-related protein 8 homolog (yeast) ATXN10 5.32 6.64 5.95 5.239 4.191 5.033 −2.186 0.0492101 ataxin 10 FAM19A5 4.829 5.296 5.82 4.693 4.017 4.126 −2.183 0.0392123 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 KANK2 5.632 5.218 6.364 4.176 4.505 5.139 −2.183 0.0411233 KN motif and ankyrin repeat domains 2 RBL2 5.109 5.291 5.141 4.1 4.165 3.967 −2.182 0.0047113 retinoblastoma-like 2 (p130) PARP9 4.715 4.209 4.095 3.378 3.084 3.063 −2.181 0.0106124 poly (ADP-ribose) polymerase family, member 9 ARL5B 5.438 6.97 6.132 4.806 5.358 5.008 −2.18 0.0482765 ADP-ribosylation factor-like 5B NAALADL1 3.036 4.125 3.538 2.026 2.414 2.735 −2.179 0.0262732 N-acetylated alpha-linked acidic dipeptidase-like 1 ZNF136 4.065 5.469 4.463 3.792 2.941 3.603 −2.179 0.0380053 zinc finger protein 136 GMPR2 5.416 6.605 5.506 4.293 5.013 4.952 −2.179 0.0486785 guanosine monophosphate reductase 2 ASNSD1 6.17 5.863 5.63 4.891 4.74 4.704 −2.178 0.0093618 asparagine synthetase domain containing 1 PPP1R2 6.466 6.953 6.426 5.831 5.266 5.797 −2.176 0.0276697 protein phosphatase 1, regulatory (inhibitor) subunit 2 SSX2IP 3.866 3.987 3.999 3.009 2.867 2.626 −2.174 0.0061644 synovial sarcoma, X breakpoint 2 interacting protein TMCC2 3.745 4.31 2.895 3.19 1.787 1.943 −2.174 0.0408972 transmembrane and coiled-coil domain family 2 ZNF433 4.764 4.688 4.431 3.302 3.57 3.73 −2.17 0.00955 zinc finger protein 433 N4BP1 5.332 7.022 5.553 4.74 4.634 4.216 −2.168 0.0253373 NEDD4 binding protein 1 SCN4B 5.813 6.755 5.931 4.697 5.032 4.939 −2.167 0.0129742 sodium channel, voltage-gated, type IV, beta CYR61 13.134 14.844 13.731 12.368 12.871 12.615 −2.167 0.0352357 cysteine-rich, angiogenic inducer, 61 GRIA4 5.032 6.7 5.367 4.252 4.47 4.229 −2.165 0.0254225 glutamate receptor, ionotrophic, AMPA4 NEU1 6.338 7.076 7.24 5.526 5.885 6.126 −2.164 0.0339171 sialidase 1 (lysosomal sialidase) SLC22A18 4.805 5.171 5.789 3.692 4.462 4.213 −2.163 0.0290492 solute carrier family 22, member 18 LEPROT 7.673 8.529 7.454 6.342 6.971 6.798 −2.162 0.0260492 leptin receptor overlapping transcript CLU 9.08 9.407 8.565 7.554 7.971 8.014 −2.156 0.0163368 clusterin STK38L 6.498 8.732 6.89 5.782 5.571 5.816 −2.155 0.0243615 serine/threonine kinase 38 like AHR 9.818 10.662 10.235 8.478 9.555 9.473 −2.154 0.0474544 aryl hydrocarbon receptor MTCP1NB 4.388 4.909 4.053 3.541 3.118 3.282 −2.152 0.017742 mature T-cell proliferation 1 neighbor PDHX 4.679 5.619 5.57 4.028 3.573 4.62 −2.152 0.0297761 pyruvate dehydrogenase complex, component X TJP1 8.937 9.083 9.001 7.897 7.508 8.015 −2.15 0.0059755 tight junction protein 1 (zona occludens 1) GAB1 7.107 7.245 6.863 5.285 6.251 6.005 −2.147 0.0155835 GRB2-associated binding protein 1 C14orf145 1.515 2.224 2.946 1.121 1.07 1.163 −2.147 0.0394698 chromosome 14 open reading frame 145 N4BP2L1 5.638 5.979 7.028 4.537 4.894 5.153 −2.146 0.0211548 NEDD4 binding protein 2-like 1 RNASE4 6.708 6.059 6.535 4.817 5.607 5.588 −2.145 0.0268448 ribonuclease, RNase A family, 4 TRAK1 8.387 8.693 8.733 7.251 7.668 7.593 −2.144 0.0098519 trafficking protein, kinesin binding 1 NT5DC1 2.739 3.932 3.493 1.999 2.832 1.818 −2.144 0.0406067 5'-nucleotidase domain containing 1 FAM135A 5.745 5.355 5.053 4.396 3.953 4.533 −2.143 0.0197152 family with sequence similarity 135, member A SDK1 5.447 6.269 5.918 4.748 4.982 4.818 −2.143 0.0226944 sidekick homolog 1, cell adhesion molecule (chicken) DNAJC12 2.574 3.312 3.349 2.283 2.214 1.033 −2.141 0.0342563 DnaJ (Hsp40) homolog, subfamily C. member 12 CKAP4 9.47 9.574 8.976 8.511 7.744 8.373 −2.14 0.0204658 cytoskeleton-associated protein 4 COPS8 5.374 5.328 5.398 4.187 4.279 4.501 −2.136 0.0069092 COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) LRRC49 4.17 4.627 5.201 3.345 3.532 3.565 −2.136 0.0174136 leucine rich repeat containing 49 GLI2 2.513 2.608 5.891 1.494 1.513 1.948 −2.136 0.0389504 GLI family zinc finger 2 PRDM6 2.128 2.974 2.636 2.205 1.033 1.201 −2.136 0.04609 PR domain containing 6 RIN3 5.965 3.642 4.043 3.31 2.996 2.549 −2.133 0.0340703 Ras and Rab interactor 3 DCAF6 7.88 8.614 8.504 7.415 7.409 7.516 −2.128 0.037928 DDB1 and CUL4 associated factor 6 NRP2 8.895 9.138 8.979 8.049 7.575 7.957 −2.127 0.0078 neuropilin 2 ALG6 4.024 3.162 3.9 2.935 1.513 2.909 −2.127 0.0435308 asparagine-linked glycosylation 6, alpha-1,3- glucosyltransferase homolog (S. cerevisiae) SNTB2 9.237 10.285 9.865 8.342 9.038 8.779 −2.124 0.0356729 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) HS2ST1 6.453 7.17 6.954 6.085 5.345 5.958 −2.122 0.0284668 heparan sulfate 2-O-sulfotransferase 1 FOXF1 3.378 3.806 4.588 2.682 2.72 3.111 −2.122 0.0368026 forkhead box F1 OS9 7.464 7.844 7.922 6.629 6.837 6.749 −2.121 0.0135301 osteosarcoma amplified 9, endoplasmic reticulum lectin SLC23A2 6.079 6.602 6.442 5.518 5.074 5.335 −2.121 0.0145553 solute carrier family 23 (nucleobase transporters), member 2 TXNDC15 4.962 5.268 5.557 4.473 3.871 4.193 −2.12 0.0178415 thioredoxin domain containing 15 PLS1 3.941 3.282 4.843 3.011 2.689 2.857 −2.12 0.0398261 plastin 1 RET 2.316 2.622 3.706 1.659 1.434 1.541 −2.115 0.0195285 ret proto-oncogene FCRL6 1.923 2.829 1.66 1.188 0.609 0.842 −2.115 0.0213544 Fc receptor-like 6 BMH 5.261 6.049 6.319 4.254 4.97 4.99 −2.113 0.03346 BMI1 polycomb ring finger oncogene SEP10 6.335 6.871 6.753 5.794 5.47 5.56 −2.11 0.0146104 septin 10 SVEP1 4.89 4.507 5.425 3.956 3.744 3.813 −2.109 0.0196466 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 FZD8 7.939 9.902 8.203 7.127 7.101 7.356 −2.108 0.0287572 frizzled homolog 8 (Drosophila) MXD3 4.435 4.55 4.466 3.798 3.263 3.393 −2.105 0.0150519 MAX dimerization protein 3 SCN2A 3.793 4.228 4.08 2.99 3.154 2.758 −2.104 0.011657 sodium channel, voltage-gated, type II, alpha subunit CMAS 4.475 5.194 4.854 3.741 3.592 4.121 −2.104 0.025019 cytidine monophosphate N-acetylneuraminic acid synthetase FAM108B1 8.186 7.406 7.579 6.333 7.081 6.753 −2.103 0.0379631 family with sequence similarity 108, member B1 CYC1 6.074 7.784 6.839 5.767 5.108 6.026 −2.103 0.0443879 cytochrome c-1 JMJD1C 8.166 8.976 8.627 7.266 7.897 7.556 −2.101 0.0315289 jumonji domain containing 1C C1orf203 3.89 3.791 4.224 2.908 2.722 2.931 −2.098 0.0078486 No description MAP4K3 5.697 6.698 6.767 5.112 5.097 5.699 −2.096 0.0405173 mitogen-activated protein kinase kinase kinase kinase 3 CORO6 4.502 4.552 4.158 3.436 3.912 3.059 −2.094 0.0393604 coronin 6 NGF 3.355 6.98 4.021 3.023 2.289 3.04 −2.093 0.0426365 nerve growth factor (beta polypeptide) LOC439994 1.587 1.388 2.008 0.323 0.988 0.429 −2.092 0.0215983 No description TTLL3 6.979 7.844 8.03 6.065 6.791 6.779 −2.092 0.0431373 tubulin tyrosine ligase-like family, member 3 PXDN 8.039 7.302 7.262 6.47 6.481 6.198 −2.09 0.0159562 peroxidasin homolog (Drosophila) TMEM195 2.977 2.224 1.784 1.299 1.07 1.163 −2.087 0.0257909 transmembrane protein 195 CENPV 3.075 3.942 3.595 2.09 2.261 2.882 −2.085 0.0272333 centromere protein V CEP78 3.822 4.823 4.051 3.267 3.497 2.763 −2.084 0.0395328 centrosomal protein 78kDa FLOT1 9.324 9.369 9.921 8.21 8.863 8.474 −2.083 0.0265579 flotillin 1 BRI3 7.845 8.643 8.117 7.061 6.991 7.224 −2.079 0.0160528 brain protein 13 SLC7A7 2.167 2.039 2.812 0.573 1.758 1.277 −2.077 0.0368369 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 CLSTN1 8.254 9.029 9.234 7.975 7.335 8.044 −2.077 0.0402561 calsyntenin 1 ABLIM2 3.214 1.897 2.421 1.366 1.033 1.797 −2.077 0.0445417 actin binding LIM protein family, member 2 LEO1 3.447 3.846 3.642 2.589 2.094 2.986 −2.076 0.0218316 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) ARF6 10.849 11.539 11.343 10.231 10.356 10.289 −2.076 0.0246083 ADP-ribosylation factor 6 MXRA7 10.085 9.437 9.505 8.997 8.383 8.823 −2.076 0.0380897 matrix-remodelling associated 7 LYPLAL1 3.41 3.937 3.483 2.109 2.689 2.886 −2.073 0.0261408 lysophospholipase-like 1 GSTA4 4.536 4.943 4.62 2.946 3.904 3.572 −2.067 0.0152672 glutathione S-transferase alpha 4 ANTXR1 7.417 7.951 8.058 6.498 7.011 6.616 −2.067 0.017385 anthrax toxin receptor 1 ZNF100 2.274 2.95 3.016 1.969 1.434 1.386 −2.067 0.0192488 zinc finger protein 100 IQCK 3.719 3.85 3.748 2.432 2.804 2.793 −2.064 0.0072984 IQ motif containing K AMIGO2 9.975 11.687 10.612 9.401 9.813 9.567 −2.062 0.049756 adhesion molecule with Ig-like domain 2 SERPINB5 9.543 9.997 9.832 8.651 8.689 8.955 −2.059 0.0132325 serpin peptidase inhibitor, clade B (ovalbumin), member 5 JHDM1D 7.317 6.977 7.699 6.447 6.119 6.275 −2.059 0.0185347 jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) DENND4A 6.283 6.942 7.257 5.901 5.813 5.918 −2.058 0.0396351 DENN/MADD domain containing 4A FOXN3 8.114 8.813 7.907 6.867 7.361 7.302 −2.057 0.0250726 forkhead box N3 NHLRC3 4.342 3.768 4.226 3.187 3.297 2.829 −2.056 0.021486 NHL repeat containing 3 NEK6 4.38 4.71 4.889 4.074 3.37 3.34 −2.056 0.0237884 NIMA (never in mitosis gene a)-related kinase 6 SMAD1 4.588 5.428 4.422 3.41 3.549 3.939 −2.055 0.0223997 SMAD family member 1 PITPNM2 5.133 4.837 4.603 4.096 3.629 3.757 −2.052 0.0174644 phosphatidylinositol transfer protein, membrane- associated 2 DNAJC18 4.205 4.259 4.512 3.761 3.122 3.223 −2.05 0.0260635 DnaJ (Hsp40) homolog, subfamily C, member 18 FLYWCH1 7.015 7.575 7.989 6.539 6.773 6.506 −2.05 0.0460249 FLYWCH-type zinc finger 1 CAMK2D 6.865 7.607 7.908 5.864 6.874 6.213 −2.047 0.0377255 calcium/calmodulin-dependent protein kinase II delta KANK1 7.685 8.564 8.142 7.117 6.795 7.11 −2.046 0.0183795 KN motif and ankyrin repeat domains 1 RPGR 5.567 4.765 5.422 4.519 3.878 4.395 −2.038 0.0389433 retinitis pigmentosa GTPase regulator EEA1 6.183 6.981 6.907 5.956 5.256 5.84 −2.035 0.0399392 early endosome antigen 1 ISOC1 5.451 6.642 5.654 4.443 4.63 4.934 −2.033 0.0224247 isochorismatase domain containing 1 GAA 7.578 8.311 7.888 6.56 7.287 6.76 −2.033 0.0278837 glucosidase, alpha; acid TPBG 7.804 8.991 8.29 7.417 7.181 7.267 −2.032 0.0336274 trophoblast glycoprotein VIPR2 4.101 3.29 3.819 3.078 2.638 2.666 −2.032 0.0382836 vasoactive intestinal peptide receptor 2 HOXC5 1.908 1.568 1.578 0.631 0.886 0.327 −2.031 0.0138377 homeobox C5 APLP2 10.382 11.403 10.325 9.54 9.639 9.303 −2.03 0.0218459 amyloid beta (A4) precursor-like protein 2 LGALS8 6.594 6.763 7.32 5.597 6.002 5.742 −2.029 0.0164298 lectin, galactoside-binding, soluble, 8 BBS4 3.455 4.089 3.659 3.016 2.758 2.434 −2.029 0.0263397 Bardet-Biedl syndrome 4 RFX2 7.057 7.475 8.582 6.174 6.633 6.454 −2.029 0.0287987 regulatory factor X, 2 (influences HLA class II expression) MYEF2 3.071 4.258 2.818 1.797 2.156 2.19 −2.028 0.0230987 myelin expression factor 2 YTHDF3 7.498 8.186 8.215 6.835 7.064 7.198 −2.024 0.0356851 YTH domain family, member 3 EPHX2 5.183 5.734 5.048 2.657 4.718 4.173 −2.023 0.0336517 epoxide hydrolase 2, cytoplasmic C4orf31 1.562 1.608 1.873 0.86 0.515 0.631 −2.018 0.0116856 chromosome 4 open reading frame 31 TAF5 4.71 4.834 4.491 3.561 3.672 3.823 −2.015 0.0114166 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa FBXL17 5.346 6.033 5.495 4.833 4.848 4.336 −2.015 0.035024 F-box and leucine-rich repeat protein 17 LPAR4 1.942 1.824 3.422 1.121 0.814 1.163 −2.014 0.0281706 lysophosphatidic acid receptor 4 ACN9 2.548 3.705 2.724 2.233 1.538 1.741 −2.014 0.0339243 ACN9 homolog (S. cerevisiae) XRCC6BP1 2.233 2.602 2.417 1.407 1.145 1.98 −2.014 0.0426172 XRCC6 binding protein 1 BTN2A2 4.247 4.8 5.047 3.663 3.791 4.03 −2.013 0.0475131 butyrophilin, subfamily 2, member A2 SMPD1 5.118 5.35 4.897 4.27 3.889 4.228 −2.011 0.0168555 sphingomyelin phosphodiesterase 1, acid lysosomal C16orf62 4.869 4.432 4.794 3.318 3.975 3.786 −2.011 0.0233269 chromosome 16 open reading frame 62 DOCK8 2.989 3.604 2.491 2.246 1.709 1.982 −2.01 0.0379016 dedicator of cytokinesis 8 RNLS 2.187 3.531 2.528 1.889 1.521 1.436 −2.01 0.0384718 renalase, FAD-dependent amine oxidase FAM69B 5.199 4.124 3.601 3.116 3.106 3.134 −2.01 0.0386735 family with sequence similarity 69, member B ACP2 4.438 4.729 4.037 3.586 3.722 3.022 −2.01 0.0391608 acid phosphatase 2, lysosomal HHAT 4.582 4.267 4.121 3.052 3.713 3.261 −2.009 0.0261 hedgehog acyltransferase MCF2L 4.875 4.289 3.851 3.285 3.499 3.122 −2.006 0.0322272 MCF.2 cell line derived transforming sequence-like TOX3 3.581 4.263 3.719 3.259 2.926 2.504 −2.006 0.0410431 TOX high mobility group box family member 3 DPCD 3.937 4.787 4.33 3.297 3.161 3.782 −2.006 0.0461909 deleted in primary ciliary dyskinesia homolog (mouse) PCBP2 10.541 11.312 11.189 10.169 10.006 10.308 −2.006 0.0497703 poly(rC) binding protein 2 PEX3 4.004 4.838 3.914 3.353 3.115 2.91 −2.005 0.0234099 peroxisomal biogenesis factor 3 SRA1 5.645 6.254 6.592 5.25 4.845 5.296 −2.005 0.0318573 steroid receptor RNA activator 1 SFXN3 6.768 6.93 6.144 5.685 5.765 5.849 −2.005 0.0482307 sideroflexin 3 CDK5RAP2 6.479 5.856 6.323 5.07 5.477 4.979 −2.003 0.0203935 CDK5 regulatory subunit associated protein 2 UBE2D1 6.513 7.058 6.91 5.961 5.887 5.913 −1.996 0.0226236 ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) APIP 4.551 5.085 5.259 4.092 3.608 4.088 −1.996 0.0245518 APAF1 interacting protein CTPS2 4.726 5.25 5.554 4.224 4.04 4.558 −1.995 0.0472297 CTP synthase II DOK1 3.616 2.673 2.312 1.679 1.944 1.652 −1.991 0.0373306 docking protein 1, 62kDa (downstream of tyrosine kinase 1) BCAN 4.29 3.92 3.501 3.013 2.809 2.928 −1.989 0.025107 brevican MSH6 5.974 6.55 6.718 5.558 5.434 5.716 −1.989 0.0477306 mutS homolog 6 (E. coli) NDUFV1 8.321 8.457 8.493 7.141 7.586 7.466 −1.988 0.0112742 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa C1QTNF9 3.411 3.549 2.777 2.157 2.488 2.421 −1.988 0.0432525 C1q and tumor necrosis factor related protein 9 TSHZ3 7.326 7.827 7.639 6.67 6.426 6.65 −1.985 0.0140388 teashirt zinc finger homeobox 3 ELOVL5 9.261 9.505 9.973 8.21 8.989 8.552 −1.977 0.0362467 ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) PCDHB4 1.959 3.545 2.5 1.121 1.521 1.59 −1.972 0.0333419 protocadherin beta 4 SAMD9L 2.269 1.793 1.935 1.121 0.814 1.163 −1.971 0.0190084 sterile alpha motif domain containing 9-like FAM129B 7.798 8.357 8.217 7.525 6.819 7.207 −1.971 0.0361537 family with sequence similarity 129, member B GRAMD1C 2.049 2.586 2.49 1.494 1.513 1.525 −1.968 0.0279817 GRAM domain containing 1C CACHD1 7.483 7.916 8.509 6.654 7.075 6.94 −1.967 0.0282085 cache domain containing 1 SUMF2 6.669 6.58 6.593 5.466 5.914 5.619 −1.964 0.0152486 sulfatase modifying factor 2 PHF2 7.24 6.691 7.342 6.055 6.333 6.267 −1.964 0.0375531 PHD finger protein 2 OAT 8.36 8.97 9.02 7.977 7.743 8.047 −1.963 0.0423954 ornithine aminotransferase CRY2 8.296 7.579 7.79 6.819 6.931 6.693 −1.96 0.0162338 cryptochrome 2 (photolyase-like) LRRN3 2.556 3.592 3.61 1.773 1.758 2.639 −1.96 0.0351735 leucine rich repeat neuronal 3 REV3L 6.391 6.932 6.546 5.421 5.734 5.87 −1.959 0.0251263 REV3-like, catalytic subunit of DNA polymerase zeta (yeast) RWDD2B 3.456 3.548 3.094 2.49 1.818 2.614 −1.954 0.0247056 RWD domain containing 2B LAMB2 9.981 10.127 10.151 8.972 9.161 9.232 −1.953 0.0100064 laminin, beta 2 (laminin S) PDE4D 4.961 4.533 5.066 3.785 4.062 3.995 −1.953 0.0258983 phosphodiesterase 4D, cAMP-specific FKBP10 7.587 7.865 7.812 6.932 6.564 6.847 −1.952 0.0140245 FK506 binding protein 10, 65 kDa PACSIN2 6.267 5.655 5.912 4.69 5.422 4.813 −1.952 0.0362875 protein kinase C and casein kinase substrate in neurons 2 PTP RA 6.812 7.072 7.548 6.48 6.108 5.855 −1.95 0.0314552 protein tyrosine phosphatase, receptor type, A LOC96610 7.007 7.055 7.429 6.094 6.093 6.063 −1.949 0.0081849 No description DAP 7.398 7.184 6.745 6.437 5.746 6.32 −1.948 0.0407155 death-associated protein USP13 5.622 5.675 5.204 4.661 4.093 4.777 −1.947 0.0283559 ubiquitin specific peptidase 13 (isopeptidase T-3) QPRT 4.496 4.305 4.969 3.537 3.538 3.387 −1.945 0.012522 quinolinate phosphoribosyltransferase PAQR8 2.741 2.794 2.656 1.837 1.569 1.837 −1.941 0.0095214 progestin and adipoQ receptor family member VIII BTBD2 6.98 6.706 6.657 5.599 6.283 5.749 −1.94 0.0348344 BTB (POZ) domain containing 2 KCTD10 6.769 7.775 7.099 6.355 5.813 6.392 −1.939 0.0396938 potassium channel tetramerisation domain containing 10 TAB3 7.222 7.489 7.819 6.526 6.535 6.594 −1.937 0.0191028 TGF-beta activated kinase 1/MAP3K7 binding protein 3 ZHX3 6.196 5.663 6.518 5.564 4.824 5.048 −1.937 0.0437304 zinc fingers and homeoboxes 3 UBTD2 8.766 8.454 8.623 7.447 7.893 7.672 −1.933 0.0182493 ubiquitin domain containing 2 SOAT1 6.093 5.56 6.267 5.161 5.024 5.142 −1.933 0.0383265 sterol O-acyltransferase 1 HERC5 4.121 3.227 3.852 2.281 2.902 2.966 −1.932 0.0400286 hect domain and RLD 5 C5orf15 6.856 7.352 6.961 6.014 6.002 6.328 −1.928 0.022072 chromosome 5 open reading frame 15 PBX1 7.546 7.779 7.212 6.032 6.949 6.6 −1.926 0.0389647 pre-B-cell leukemia homeobox 1 XBP1 8.89 9.559 9.919 8.615 8.283 8.652 −1.924 0.0490892 X-box binding protein 1 RECK 6.333 6.499 7.046 5.532 5.558 5.67 −1.92 0.018285 reversion-inducing-cysteine-rich protein with kazal motifs LRRC28 3.956 4.142 3.96 2.533 3.259 3.022 −1.916 0.0156893 leucine rich repeat containing 28 ZBTB47 6.153 5.575 6.153 5.218 5.076 5.049 −1.913 0.0377184 zinc finger and BTB domain containing 47 PGAP2 4.453 4.786 4.669 3.367 3.924 3.735 −1.911 0.0210174 post-GPI attachment to proteins 2 B3GNT2 6.15 6.692 5.882 4.948 5.314 5.36 −1.91 0.0255513 UDP-GlcNAc:betaGal beta-1,3-N- acetylglucosaminyltransferase 2 WWC3 6.875 7.551 7.077 6.282 5.943 6.57 −1.908 0.0437941 WWC family member 3 PSMB8 7.598 6.732 6.464 5.533 5.993 6.012 −1.906 0.0363597 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) EIF2C4 3.814 4.749 4.081 3.323 2.884 3.294 −1.904 0.0303212 eukaryotic translation initiation factor 2C, 4 ZNF654 6.052 6.304 6.283 5.088 5.354 5.625 −1.904 0.0306432 zinc finger protein 654 HDGFRP3 6.937 6.894 6.802 5.966 5.614 6.237 −1.903 0.0223853 No description PHLPP1 7.448 8.298 7.888 6.756 7.061 6.96 −1.903 0.0337197 PH domain and leucine rich repeat protein phosphatase 1 TMEM66 9.206 10.16 9.704 8.362 8.86 8.776 −1.903 0.0338299 transmembrane protein 66 STK17A 10.47 11.038 10.312 9.384 9.965 9.769 −1.903 0.0461401 serine/threonine kinase 17a ARPC1B 7.783 6.124 6.302 5.364 5.374 5.604 −1.902 0.0362538 actin related protein 2/3 complex, subunit 1B, 41kDa FBXO31 8.203 7.968 7.896 7.276 6.953 7.236 −1.9 0.0226744 F-box protein 31 PNKD 6.235 6.945 6.241 5.39 5.816 5.309 −1.9 0.0355677 paroxysmal nonkinesigenic dyskinesia TMEM170A 4.902 5.351 4.615 4.366 3.946 3.978 −1.898 0.0480439 transmembrane protein 170A CENPJ 1.684 2.298 1.855 1.121 0.814 0.935 −1.893 0.0203155 centromere protein J ARHGEF12 7.547 8.064 7.992 7.073 7.051 7.133 −1.891 0.0413594 Rho guanine nucleotide exchange factor (GEF) 12 CCDC85B 8.221 9.793 8.37 7.303 7.633 7.612 −1.89 0.0345239 coiled-coil domain containing 85B EFNA3 4.067 5.021 5.075 3.21 4.157 3.418 −1.89 0.0412871 ephrin-A3 PLD3 8.563 8.821 8.912 8.12 7.646 7.646 −1.889 0.020812 phospholipase D family, member 3 HGSNAT 6.968 7.196 7.474 6.278 6.457 6.174 −1.889 0.0228296 heparan-alpha-glucosaminide N-acetyltransferase PAM 8.212 7.757 7.871 7.5 6.491 6.955 −1.887 0.0442656 peptidylglycine alpha-amidating monooxygenase PDZD11 3.821 4.508 3.801 3.144 3.128 2.886 −1.886 0.0264578 PDZ domain containing 11 RASA3 4.975 5.678 5.457 4.544 4.42 4.541 −1.886 0.036671 RAS p21 protein activator 3 DNAJC15 4.901 5.454 4.721 4.071 3.864 3.986 −1.885 0.0183967 DnaJ (Hsp40) homolog, subfamily C, member 15 C1orf21 9.795 10.108 10.069 8.851 9.324 9.155 −1.884 0.026706 chromosome 1 open reading frame 21 SATB1 4.072 4.687 3.951 3.29 3.039 3.262 −1.881 0.0207469 SATB homeobox 1 LIMK2 7.39 8.086 7.634 6.722 6.844 6.658 −1.881 0.0238635 LIM domain kinase 2 PCSK5 6.057 6.665 6.646 5.373 5.577 5.754 −1.88 0.0368606 proprotein convertase subtilisin/kexin type 5 IPW 4.662 5.757 4.989 3.927 4.079 4.104 −1.879 0.0272834 imprinted in Prader-Willi syndrome (non-protein coding) BPHL 4.172 5.069 4.172 3.267 3.786 3.286 −1.873 0.0388188 biphenyl hydrolase-like (serine hydrolase) APPL2 5.836 6.134 6.679 5.229 5.089 5.561 −1.873 0.0430844 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 COL4A1 11.511 10.868 10.804 10.423 9.902 10.169 −1.869 0.0452579 collagen, type IV, alpha 1 ESD 6.532 7.036 6.76 5.63 5.739 6.35 −1.869 0.0494362 esterase D ARID5A 10.643 8.878 9.24 8.443 8.342 8.001 −1.864 0.0355491 AT rich interactive domain 5A (MRF1-like) SCRN1 3.806 5.412 3.967 3.148 2.909 3.225 −1.863 0.0331394 secernin 1 CREBL2 4.947 5.739 5.347 4.128 4.844 4.17 −1.86 0.0452293 cAMP responsive element binding protein-like 2 BTG1 9.78 10.114 9.662 8.28 9.219 9.025 −1.859 0.0358317 B-cell translocation gene 1, anti-proliferative FIS1 6.996 6.794 7.064 5.525 6.127 6.171 −1.857 0.021114 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) PEX19 5.324 5.429 5.39 4.565 4.498 4.268 −1.855 0.0115633 peroxisomal biogenesis factor 19 ZNF622 6.962 7.582 6.792 6.071 6.306 6.071 −1.855 0.0306647 zinc finger protein 622 PCDHB16 4.326 4.819 4.317 3.435 3.937 2.998 −1.855 0.0333061 protocadherin beta 16 PSEN1 7.303 6.693 7.121 6.325 6.064 6.229 −1.855 0.0392559 presenilin 1 MLXIPL 3.315 3.043 3.968 2.689 2.427 2.421 −1.852 0.0429928 MLX interacting protein-like HCFC2 3.821 4.058 4.145 3.39 3.172 2.479 −1.848 0.0335015 host cell factor C2 RAB8B 6.612 6.855 7.729 6.194 5.822 5.969 −1.848 0.034765 RAB8B, member RAS oncogene family TMEM200A 4.059 4.575 4.127 3.689 3.039 3.457 −1.848 0.0473142 transmembrane protein 200A SLC2A5 2.585 2.129 2.504 1.922 1.297 1.244 −1.847 0.0384789 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 BLMH 5.235 4.82 4.869 4.326 3.797 4.353 −1.844 0.0494856 bleomycin hydrolase ARAP3 6.819 6.536 6.918 6.16 5.626 5.937 −1.843 0.0354518 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 NBPF14 2.936 3.328 3.196 2.277 2.332 2.316 −1.84 0.0216677 neuroblastoma breakpoint family, member 14 THRA 5.737 5.742 5.643 4.59 5.183 4.858 −1.839 0.0347263 thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) RILP 5.484 5.094 4.793 4.397 4.359 3.915 −1.838 0.0403191 Rab interacting lysosomal protein ARSA 5.544 5.456 5.135 4.579 4.171 4.802 −1.837 0.0404822 arylsulfatase A NIN 6.549 6.291 7.402 5.585 5.981 5.672 −1.837 0.0452951 ninein (GSK3B interacting protein) FRCP 6.454 6.523 6.223 5.641 5.179 5.646 −1.836 0.0243865 prolylcarboxypeptidase (angiotensinase C) ALDH16A1 6.301 6.079 6.295 5.738 5.407 5.204 −1.834 0.0448737 aldehyde dehydrogenase 16 family, member A1 OLFM2 6.579 6.24 6.458 5.369 5.748 5.541 −1.829 0.0235666 olfactomedin 2 PTPN12 7.777 8.563 8.109 7.24 7.217 7.366 −1.826 0.0400558 protein tyrosine phosphatase, non-receptor type 12 ALAS1 5.525 4.921 4.777 4.098 4.187 3.909 −1.824 0.0236982 aminolevulinate, delta-, synthase 1 TP53INP2 6.269 6.194 5.851 5.315 5.405 5.293 −1.821 0.0364234 tumor protein p53 inducible nuclear protein 2 NCSTN 7.226 7.245 6.816 6.307 6.361 6.38 −1.821 0.0428568 nicastrin UBE2L6 6.67 6.296 7.033 5.471 5.84 5.808 −1.817 0.0295371 ubiquitin-conjugating enzyme E2L 6 RAB1A 9.587 10.632 9.977 8.97 9.116 9.214 −1.817 0.0421342 RAB1 A, member RAS oncogene family DCP2 5.431 5.845 5.806 4.683 4.944 4.97 −1.816 0.0320612 DCP2 decapping enzyme homolog (S. cerevisiae) ATG2B 4.749 5.633 5.108 4.247 4.306 4.177 −1.816 0.0382908 ATG2 autophagy related 2 homolog B (S. cerevisiae) RFX7 4.815 5.979 5.024 4.364 4.337 3.956 −1.814 0.0418924 regulatory factor X, 7 STARD3NL 6.961 6.848 7.623 5.992 6.133 6.114 −1.81 0.0192845 STARD3 N-terminal like ZNF185 5.936 7.256 5.959 5.08 5.193 5.452 −1.809 0.041657 zinc finger protein 185 (LIM domain) C14orf37 2.144 3.173 2.09 1.659 1.235 1.386 −1.809 0.042072 chromosome 14 open reading frame 37 C19orf71 2.108 1.513 1.885 1.033 0.609 1.277 −1.804 0.0493954 chromosome 19 open reading frame 71 RDH10 5.358 5.313 5.571 4.507 4.869 4.463 −1.802 0.0345739 retinol dehydrogenase 10 (all-trans) TUBGCP3 2.672 3.361 3.246 2.035 1.827 2.607 −1.796 0.0478837 tubulin, gamma complex associated protein 3 CPA1 2.495 2.677 2.229 1.818 1.387 1.779 −1.793 0.0431874 carboxypeptidase A1 (pancreatic) LSM2 5.896 6.862 6.005 5.167 5.338 5.141 −1.787 0.0312671 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) KIAA1715 4.566 4.647 5.02 4.04 3.728 4.039 −1.787 0.0385719 KIAA1715 HDAC11 5.146 4.885 4.85 3.929 4.247 4.31 −1.784 0.0349238 histone deacetylase 11 PRPS2 5.036 4.875 5.136 4.202 3.928 4.442 −1.783 0.0339679 phosphoribosyl pyrophosphate synthetase 2 FAM102B 3.846 4.422 4.164 3.012 3.06 3.694 −1.783 0.0475567 family with sequence similarity 102, member B TRAF3IP2 6.176 6.007 6.301 5.464 5.343 5.183 −1.782 0.0233197 TRAF3 interacting protein 2 SLC44A1 6.318 6.669 6.553 5.12 5.72 5.901 −1.782 0.0358188 solute carrier family 44, member 1 FAM131B 3.463 2.983 3.089 2.261 2.284 2.171 −1.776 0.0175703 family with sequence similarity 131, member B PLK3 8.736 9.086 8.615 7.787 8.042 7.952 −1.775 0.0241947 polo-like kinase 3 CHMP5 6.415 6.698 6.278 5.355 5.896 5.588 −1.775 0.0368749 chromatin modifying protein 5 CASKIN1 6.034 6.115 6.007 5.063 5.531 5.213 −1.767 0.0354711 CASK interacting protein 1 TIMP3 10.062 10.19 10.06 8.779 9.51 9.244 −1.764 0.0293153 TIMP metallopeptidase inhibitors SLC38A10 5.866 5.44 5.628 4.936 4.795 4.817 −1.754 0.0310253 solute carrier family 38, member 10 SNX15 4.395 4.502 4.088 3.483 3.277 3.691 −1.754 0.0319804 sorting nexin 15 C6orf89 4.834 5.108 4.835 4.299 3.678 4.234 −1.752 0.0402061 chromosome 6 open reading frame 89 PDE8A 5.131 5.016 5.251 4.443 4.344 4.171 −1.751 0.0231409 phosphodiesterase 8A CBLN3 2.427 2.132 1.837 1.366 1.033 1.348 −1.746 0.0321392 cerebellin 3 precursor WBP2 8.442 9.157 8.249 7.459 7.641 7.762 −1.742 0.0330715 WW domain binding protein 2 AFF1 7.402 6.832 6.905 6.261 6.031 6.346 −1.742 0.0407706 AF4/FMR2 family, member 1 ZMIZ1 7.884 8.805 8.106 7.084 7.546 7.373 −1.74 0.047292 zinc finger, MIZ-type containing 1 PDSS2 2.442 2.957 2.442 2.008 1.645 1.747 −1.737 0.0448494 prenyl (decaprenyl) diphosphate synthase, subunit 2 RPS3A 13.092 12.979 13.175 12.205 12.185 12.426 −1.733 0.0221693 ribosomal protein S3A RCN1 9.114 9.436 9.54 8.645 8.321 8.792 −1.73 0.0490821 reticulocalbin 1, EF-hand calcium binding domain AKTIP 3.407 3.791 3.513 3.002 2.432 2.802 −1.728 0.0424605 AKT interacting protein PRC1 3.176 3.456 3.994 2.388 2.689 2.688 −1.727 0.0332646 protein regulator of cytokinesis 1 BCAS2 4.823 4.777 5.952 3.989 4.137 4.329 −1.726 0.0482571 breast carcinoma amplified sequence 2 BTBD3 5.275 5.89 5.901 5.114 4.639 4.58 −1.725 0.0416785 BTB (POZ) domain containing 3 BACE1 6.321 6.371 6.073 5.539 5.557 5.329 −1.72 0.0305774 beta-site APP-cleaving enzyme 1 PPFIBP1 9.97 10.098 9.82 9.188 9.301 9.177 −1.72 0.0307291 PTPRF interacting protein, binding protein 1 (liprin beta 1) CSRP2 7.912 8.296 8.274 7.174 7.518 7.485 −1.714 0.0447643 cysteine and glycine-rich protein 2 DCTN2 6.81 8.043 7.1 6.323 6.411 6.113 −1.714 0.0450118 dynactin 2 (p50) C12orf23 6.408 6.653 6.495 5.447 5.72 5.939 −1.711 0.033802 chromosome 12 open reading frame 23 C6orf211 3.233 3.383 3.058 2.283 2.575 2.602 −1.711 0.0440774 chromosome 6 open reading frame 211 ATP9A 5.764 5.913 5.866 4.898 5.14 5.137 −1.709 0.0238277 ATPase, class II, type 9A ZDHHC21 2.477 3.003 2.43 1.659 1.787 1.747 −1.705 0.026691 zinc finger, DHHC-type containing 21 FEM1C 7.569 7.45 8.013 6.741 6.804 7.004 −1.7 0.0384145 fem-1 homolog c (C. elegans) RPL3 14.158 14.27 14.309 13.394 13.58 13.476 −1.699 0.0233484 ribosomal protein L3 MYL5 3.147 3.453 3.741 2.794 2.551 2.688 −1.699 0.0498118 myosin, light chain 5, regulatory PTGER 2.302 2.112 3.379 1.556 1.434 1.541 −1.695 0.0395621 prostaglandin F receptor (FP) MED29 6.927 6.258 6.351 5.826 5.497 5.611 −1.695 0.0411963 mediator complex subunit 29 EIF4E 8.675 8.976 8.845 7.917 8.085 8.182 −1.694 0.0317007 eukaryotic translation initiation factor 4E ORAI3 3.41 4.007 3.185 2.759 2.429 2.695 −1.69 0.0419911 ORAI calcium release-activated calcium modulator 3 KRTCAP2 7.038 6.953 6.587 5.905 6.283 6.079 −1.688 0.0470816 keratinocyte associated protein 2 CD9 9.431 10.283 9.52 8.766 8.73 9.017 −1.686 0.046349 CD9 molecule SLC25A12 5.854 6.393 5.814 5.084 5.106 5.392 −1.68 0.0444022 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 AP2M1 7.971 8.589 8.003 7.488 7.351 7.223 −1.679 0.0439171 adaptor-related protein complex 2, mu 1 subunit RBMS1 9.889 9.586 10.14 9.181 9.02 9.149 −1.671 0.0480582 RNA binding motif, single stranded interacting protein 1 CBLB 8.667 8.365 8.155 7.625 7.73 7.447 −1.67 0.0402633 Cas-Br-M (murine) ecotropic retroviral transforming sequence b KLF3 7.554 7.38 7.413 6.97 6.296 6.681 −1.66 0.0476261 Kruppel-like factor 3 (basic) YWHAH 9.163 9.848 9.242 8.458 8.518 8.727 −1.651 0.0446805 tyrosine 3-monooxygenase/tryptophan 5- monooxygenase activation protein, eta polypeptide USP3 6.299 6.883 6.289 5.68 5.567 5.593 −1.65 0.0325585 ubiquitin specific peptidase 3 BSN 1.366 1.651 1.58 0.86 0.848 0.886 −1.646 0.0453846 bassoon (presynaptic cytomatrix protein) LRTOMT 3.917 3.586 3.569 2.963 3.048 2.864 −1.631 0.0414696 leucine rich transmembrane and 0- methyltransferase domain containing LBR 7.479 7.324 7.546 6.753 6.847 6.777 −1.623 0.0433569 lamin B receptor FAM172A 4.3 4.88 4.262 3.662 3.615 3.613 −1.607 0.0373378 family with sequence similarity 172, member A FAM54B 5.931 6.416 6.044 5.319 5.373 5.432 −1.592 0.043123 family with sequence similarity 54, member B SH3GLB1 8.583 8.42 8.412 7.519 7.805 7.919 −1.585 0.0451227 SH3-domain GRB2-like endophilin B1 SLC39A1 8.316 8.325 8.437 7.783 7.559 7.751 −1.573 0.0448995 solute carrier family 39 (zinc transporter), member 1 LAMP1 8.84 9.256 8.907 8.333 8.21 8.274 −1.551 0.0447006 lysosomal-associated membrane protein 1 SPRED1 8.537 8.551 9.018 7.944 7.96 7.944 −1.524 0.0459176 sprouty-related, EVH1 domain containing 1 Higher Expresion in Parous BPNT1 10.259 10.169 10.19 10.843 10.823 10.817 1.552 0.038358 3′(2′), 5′-bisphosphate nucleotidase 1 CCDC124 6.993 7.012 6.866 7.891 7.507 7.619 1.56 0.0446433 coiled-coil domain containing 124 BCL2L2 7.758 7.328 7.727 8.26 8.408 8.308 1.569 0.0498641 BCL2-like 2 FDPSL2A 4.21 4.018 4.326 4.807 4.948 4.862 1.571 0.0443743 No description WDR83 3.491 3.624 3.638 4.151 4.278 4.475 1.581 0.0391228 WD repeat domain 83 LOC339290 6.475 6.494 6.39 6.984 7.323 7.136 1.582 0.043817 No description RMND1 1.994 1.728 1.858 2.525 2.637 2.477 1.587 0.0420505 required for meiotic nuclear division 1 homolog (S. cerevisiae) TRDMT1 3.95 4.052 3.968 4.797 4.509 4.637 1.589 0.0488517 tRNA aspartic acid methyltransferase 1 BCKDHB 5.685 5.641 5.49 6.46 6.159 6.315 1.595 0.0417142 branched chain keto acid dehydrogenase E1, beta polypeptide LOC389834 6.661 6.244 6.623 7.298 7.206 7.317 1.597 0.0379559 No description OR1J1 5.108 5.079 5.036 5.585 5.786 5.764 1.599 0.0470509 olfactory receptor, family 1, subfamily J, member 1 ZNF77 5.954 5.398 5.745 6.634 6.398 6.374 1.602 0.0488445 zinc finger protein 77 MAN1A2 4.472 4.381 4.03 4.916 5.063 5.113 1.603 0.0468119 mannosidase, alpha, class 1A, member 2 ZMYM4 6.09 5.738 5.737 6.616 6.677 6.42 1.605 0.0497353 zinc finger, MYM-type 4 CNN3 11.012 10.759 11.163 11.699 11.705 11.658 1.61 0.0449667 calponin 3, acidic ZNF345 3.518 3.381 3.267 3.957 4.183 4.08 1.613 0.0446119 zinc finger protein 345 PTPRF 8.459 8.437 8.034 9.099 9.15 8.982 1.614 0.0399463 protein tyrosine phosphatase, receptor type, F TAT 6.439 6.918 6.824 7.517 7.524 7.488 1.617 0.0368677 tyrosine aminotransferase ZFYVE27 6.791 6.062 6.697 7.305 7.397 7.439 1.624 0.0422952 zinc finger, FYVE domain containing 27 TMCO3 4.649 4.783 4.839 5.923 5.341 5.487 1.629 0.0375746 transmembrane and coiled-coil domains 3 TIMM44 8.207 8.067 8.179 8.998 8.779 8.814 1.638 0.0336589 translocase of inner mitochondrial membrane 44 homolog (yeast) GLE1 3.846 3.349 3.893 4.569 4.562 4.466 1.643 0.0343099 GLE1 RNA export mediator homolog (yeast) MAT2B 4.773 4.912 4.695 5.409 5.633 5.541 1.648 0.0320004 methionine adenosyltransferase II. beta CCDC59 8.384 8.443 7.743 9.165 9.108 8.92 1.651 0.0411891 coiled-coil domain containing 59 C1orf35 7.142 7.386 7.082 7.865 8.338 7.769 1.651 0.0493511 chromosome 1 open reading frame 35 DKFZP586I14 3.202 3.536 3.743 4.158 4.21 4.47 1.654 0.0461716 No description 20 ZNF514 1.525 2.122 2.359 2.829 2.849 2.959 1.655 0.0443436 zinc finger protein 514 THBS1 12.134 12.358 12.542 12.953 13.084 13.123 1.655 0.0479538 thrombospondin 1 MGAT4B 8.367 8.388 8.462 9.191 9.118 8.941 1.658 0.0407083 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N- acetylglucosaminyltransferase, isozyme B NAA15 8.098 7.122 8.046 8.61 8.776 8.821 1.659 0.0417672 N(alpha)-acetyltransferase 15, NatA auxiliary subunit HCG18 7.283 6.661 7.057 7.883 7.774 7.79 1.662 0.0399943 HLA complex group 18 PAK2 5.954 5.769 4.932 6.506 6.654 6.455 1.666 0.0401331 p21 protein (Cdc42/Rac)-activated kinase 2 C11orf57 6.205 6.189 5.816 6.943 6.79 6.755 1.667 0.0395471 chromosome 11 open reading frame 57 TAF4 6.912 6.129 6.813 7.398 7.559 7.553 1.67 0.0426737 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa TNFRSF6B 4.862 4.69 4.584 5.828 5.327 5.365 1.674 0.0429456 tumor necrosis factor receptor superfamily, member 6b, decoy ATAD3B 9.926 8.893 9.743 10.671 10.435 10.343 1.675 0.0468999 ATPase family, AAA domain containing 3B DNAJC5 4.243 4.121 4.242 4.868 4.949 5.017 1.678 0.0238206 DnaJ (Hsp40) homolog, subfamily C, member 5 DNAL1 3.979 3.628 3.816 4.938 4.554 4.376 1.679 0.0424848 dynein, axonemal, light chain 1 FERMT1 2.056 2.946 2.944 3.613 3.696 3.414 1.682 0.0480311 fermitin family member 1 ZC3H6 8.078 7.644 8.024 8.714 8.831 8.524 1.685 0.0427796 zinc finger CCCH-type containing 6 CCDC120 8.5 8.21 8.787 9.134 9.253 9.53 1.685 0.0463998 coiled-coil domain containing 120 TYW3 6.517 6.45 5.686 7.274 7.067 7.022 1.691 0.0453252 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) FLJ25363 5.462 5.64 5.839 6.333 6.547 6.399 1.692 0.0324512 No description LAMP3 3.677 3.914 3.42 4.603 4.622 4.18 1.693 0.0480511 lysosomal-associated membrane protein 3 DUXA 4.37 4.359 3.393 5.067 5.114 5.131 1.694 0.0304522 double homeobox A TMEM220 3.587 3.916 3.964 4.684 4.48 4.676 1.694 0.0327595 transmembrane protein 220 HNRNPH2 3.342 2.628 2.993 3.712 3.753 3.962 1.694 0.0475989 heterogeneous nuclear ribonucleoprotein H2 (H') MLL2 8.547 7.923 8.397 9.16 9.063 9.182 1.698 0.0359505 myeloid/lymphoid or mixed-lineage leukemia 2 LOC652276 5.117 4.979 4.966 5.881 5.568 5.794 1.698 0.0371639 No description TPD52L2 8.326 7.94 7.53 9.052 8.629 8.705 1.699 0.049985 tumor protein D52-like 2 CRAMP1L 5.309 5.179 5.367 5.934 6.231 6.077 1.702 0.0252429 Crm, cramped-like (Drosophila) KDM5A 7.326 7.506 7.046 8.274 7.902 8.034 1.703 0.0446577 lysine (K)-specific demethylase 5A GCK 3.668 3.51 3.653 4.849 4.359 4.282 1.708 0.0285118 glucokinase (hexokinase 4) TNPO2 8.844 8.752 8.416 9.464 9.277 9.619 1.711 0.0411462 transportin 2 C2orf60 5.485 5.396 4.839 6.217 6.171 5.976 1.712 0.0352286 chromosome 2 open reading frame 60 LSM12 8.332 7.833 7.837 8.985 8.795 8.608 1.712 0.0474329 LSM12 homolog (S. cerevisiae) RBM12B 3.02 3.441 3.29 4.224 4.062 4.061 1.72 0.0223252 RNA binding motif protein 12B C20orf20 4.852 4.43 4.509 5.614 5.37 5.213 1.72 0.0399149 chromosome 20 open reading frame 20 ZNF714 5.413 5.203 5.077 5.89 6.197 5.944 1.721 0.0349553 zinc finger protein 714 SAFB 9.773 8.217 9.75 10.509 10.559 10.235 1.724 0.0483308 scaffold attachment factor B PIGW 5.302 5.473 5.747 6.173 6.259 6.34 1.725 0.0412277 phosphatidylinositol glycan anchor biosynthesis, class W SLC2A11 6.22 6.096 5.941 6.802 7.041 6.728 1.726 0.0335215 solute carrier family 2 (facilitated glucose transporter), member 11 KRT8 6.994 6.545 6.955 7.743 8.791 7.323 1.727 0.0463418 keratin 8 BBS10 2.794 3.817 3.848 4.218 4.606 4.609 1.728 0.0498347 Bardet-Biedl syndrome 10 CNNM1 3.992 3.865 3.701 4.493 4.887 4.56 1.732 0.0350769 cyclin M1 PTPRU 6.349 5.287 6.305 7.138 7.083 7.1 1.735 0.0271024 protein tyrosine phosphatase, receptor type, U ZNF578 6.69 6.803 6.476 7.419 7.652 7.271 1.735 0.0352429 zinc finger protein 578 PICK1 6.931 7.274 7.447 8.242 7.871 7.992 1.735 0.0399535 protein interacting with PRKCA 1 FAM20B 5.521 5.55 5.574 6.171 6.347 6.422 1.737 0.0240874 family with sequence similarity 20, member B DNHD1 5.398 5.485 5.373 6.487 6.083 6.196 1.739 0.0239386 dynein heavy chain domain 1 MAPKAPK5 6.885 6.784 6.804 7.562 7.604 7.758 1.742 0.017023 mitogen-activated protein kinase-activated protein kinase 5 FAM127B 3.656 3.61 3.236 4.417 4.205 4.412 1.744 0.0278436 family with sequence similarity 127, member B ZKSCAN1 5.029 4.588 4.75 5.509 5.604 5.554 1.746 0.0362131 zinc finger with KRAB and SCAN domains 1 GATAD2B 8.028 7.51 7.654 8.314 8.669 8.673 1.746 0.0413837 GATA zinc finger domain containing 2B SULT1A4 7.342 7.625 7.108 7.995 8.288 8.146 1.746 0.0427345 sulfotransferase family, cytosolic, 1A, phenol- preferring, member 4 GCAT 2.911 3.098 2.616 3.579 3.902 3.521 1.746 0.0443951 glycine C-acetyltransferase CHCHD3 6.281 6.265 6.061 7.071 6.653 7.137 1.748 0.0489154 coiled-coil-helix-coiled-coil-helix domain containing 3 PPM1J 4.846 3.859 4.744 5.653 5.385 5.273 1.749 0.0484661 protein phosphatase, Mg2+/Mn2+ dependent, 1J OSBP2 4.917 4.194 4.607 5.464 5.414 5.274 1.749 0.0490062 oxysterol binding protein 2 FXN 6.491 6.134 6.271 6.969 7.192 7.08 1.752 0.0313386 frataxin ZNF430 2.619 2.395 2.108 3.428 3.298 2.898 1.752 0.0444094 zinc finger protein 430 SF3B14 8.53 8.578 8.524 9.417 9.168 9.34 1.753 0.0241397 No description TEKT3 2.41 2.129 2.55 3.581 3.174 2.939 1.753 0.0396044 tektin 3 PPIA 8.557 8.755 8.883 9.24 9.567 9.695 1.755 0.0444588 peptidylprolyl isomerase A (cyclophilin A) PRKDC 7.35 7.404 7.078 8.321 7.993 7.891 1.757 0.0395256 protein kinase, DNA-activated, catalytic polypeptide EARS2 5.029 4.786 4.58 5.842 5.443 5.436 1.757 0.0488588 glutamyl-tRNA synthetase 2, mitochondrial (putative) SRRT 10.565 9.813 10.27 11.087 11.092 10.952 1.762 0.0471074 serrate RNA effector molecule homolog (Arabidopsis) MRPL47 5.518 5.571 5.575 6.126 6.389 6.433 1.763 0.0292273 mitochondrial ribosomal protein L47 SERPINB9 9.638 9.456 9.181 10.174 10.457 10.27 1.764 0.0249267 serpin peptidase inhibitor, clade B (ovalbumin), member 9 NF2 8.531 8.653 8.183 9.357 9.289 9.354 1.768 0.0222659 neurofibromin 2 (merlin) DDX51 6.726 6.4 6.714 7.485 7.485 7.549 1.769 0.0161995 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 RFWD3 5.374 5.322 4.742 5.933 5.999 6.198 1.77 0.0332518 ring finger and WD repeat domain 3 STK16 5.398 5.493 5.144 6.222 6.422 5.95 1.771 0.0306575 serine/threonine kinase 16 ZNF493 7.172 6.958 7.411 7.999 8.116 7.997 1.775 0.0235408 zinc finger protein 493 RDH5 4.069 3.713 3.985 4.691 4.631 4.897 1.775 0.0284482 retinol dehydrogenase 5 (11-cis/9-cis) AP2B1 8.148 7.388 7.852 8.679 8.695 8.592 1.775 0.0408478 adaptor-related protein complex 2, beta 1 subunit AKT1 7.639 6.635 7.451 8.285 8.281 8.065 1.777 0.0425113 v-akt murine thymoma viral oncogene homolog 1 LOC344967 6.523 6.952 5.849 7.656 7.354 7.244 1.778 0.0467754 No description ASXL2 5.03 4.7 5.25 5.486 6.081 5.952 1.778 0.0477785 additional sex combs like 2 (Drosophila) TATDN3 4.528 3.673 4.039 5.158 4.857 4.871 1.779 0.0467203 TatD DNase domain containing 3 DICER1 7.907 7.596 8.199 8.943 8.737 8.739 1.781 0.0265508 dicer 1, ribonuclease type III MECR 4.902 4.053 4.726 5.581 5.56 5.494 1.783 0.0292466 mitochondrial trans-2-enoyl-CoA reductase ADORA2B 7.276 7.365 6.407 7.871 8.109 8.175 1.783 0.0328676 adenosine A2b receptor C10orf47 5.425 5.405 5.32 6.035 6.242 6.685 1.786 0.023885 chromosome 10 open reading frame 47 ACVR2B 3.501 3.912 3.675 4.521 4.512 4.507 1.786 0.0255341 activin A receptor, type I IB TIRAP 6.426 6.701 6.591 7.316 7.809 7.262 1.786 0.0293325 toll-interleukin 1 receptor (TIR) domain containing adaptor protein FAM115A 6.244 6.427 6.265 6.89 7.657 7.102 1.786 0.0359677 family with sequence similarity 115, member A SMYD4 5.631 5.526 4.979 6.272 6.469 6.061 1.787 0.0379981 SET and MYND domain containing 4 PLA2G2D 8.131 7.66 7.761 8.499 8.916 8.885 1.788 0.026867 phospholipase A2, group HD PDPK1 6.228 5.838 5.852 7.007 6.934 6.677 1.789 0.022942 3-phosphoinositide dependent protein kinase-1 LDLR 10.936 11.226 10.89 12.183 11.545 11.776 1.79 0.0468577 low density lipoprotein receptor SCAND2 5.853 5.906 5.988 6.693 6.997 6.719 1.791 0.0161294 SCAN domain containing 2 pseudogene FLJ25006 3.095 3.043 3.381 4.222 4.184 3.808 1.792 0.0241268 No description SBF1 6.391 5.542 6.277 6.999 7.236 6.917 1.797 0.0337676 SET binding factor 1 DFNB31 8.675 8.656 9.134 9.98 9.774 9.374 1.798 0.0388066 deafness, autosomal recessive 31 SIGLEC11 2.227 1.582 2.324 3.124 3.074 2.981 1.799 0.0223639 sialic acid binding Ig-like lectin 11 KIAA1967 6.316 5.912 6.155 6.838 7.003 7.108 1.8 0.0246577 KIAA1967 NELF 7.934 7.62 7.794 8.979 8.468 8.57 1.8 0.0274115 nasal embryonic LHRH factor DECR2 5.873 5.777 5.23 6.303 6.722 6.447 1.801 0.042811 2,4-dienoyl CoA reductase 2, peroxisomal SPTBN2 2.602 2.262 2.796 3.396 3.504 3.452 1.802 0.0227517 spectrin, beta, non-erythrocytic 2 NAIP 5.517 5.293 5.37 6.221 6.541 5.983 1.804 0.030933 NLR family, apoptosis inhibitory protein LOC286135 2.275 2.235 2.655 3.508 3.488 3 1.806 0.0264334 No description HEBP2 4.188 4.146 3.909 4.761 5.177 4.864 1.806 0.0270172 heme binding protein 2 EPHA2 10.088 9.573 9.707 10.683 10.941 10.328 1.806 0.0434034 EPH receptor A2 C22orf27 2.775 3.231 3.003 4.059 4.088 3.587 1.811 0.0301467 chromosome 22 open reading frame 27 SIGLEC10 3.46 3.69 3.428 4.179 4.37 4.548 1.812 0.0255269 sialic acid binding Ig-like lectin 10 TNFAIP8L1 7.647 7.401 7.785 8.412 8.733 8.259 1.813 0.0314481 tumor necrosis factor, alpha-induced protein 8-like 1 RNPC3 4.257 5.055 4.938 5.51 5.731 5.913 1.813 0.0340409 RNA-binding region (RNP1, RRM) containing 3 C19orf26 2.519 2.289 1.407 2.857 3.378 3.056 1.813 0.0444659 chromosome 19 open reading frame 26 ABCC9 5.326 5.457 5.601 6.298 6.185 6.934 1.814 0.0239837 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 AGMAT 9.172 8.309 8.874 9.734 9.981 9.67 1.815 0.0279745 agmatine ureohydrolase (agmatinase) NUDT3 6.108 6.42 6.385 7.223 7.28 7.03 1.816 0.0199664 nudix (nucleoside diphosphate linked moiety X)- type motif 3 MCM8 4.381 4.232 3.921 5.093 4.96 5.184 1.816 0.0211476 minichromosome maintenance complex component 8 C3orf74 2.988 2.711 2.926 3.714 3.572 4.065 1.816 0.0230722 chromosome 3 open reading frame 74 SEC16A 8.821 8.021 8.575 9.681 9.147 9.371 1.816 0.0422158 SEC16 homolog A (S. cerevisiae) ANKS4B 7.654 7.234 7.588 8.337 8.45 8.513 1.817 0.016246 ankyrin repeat and sterile alpha motif domain containing 4B POM121L8P 4.16 4.273 3.775 4.895 5.238 4.636 1.817 0.0437376 POM121 membrane glycoprotein-like 8 pseudogene GEMIN5 4.673 4.726 4.172 5.652 5.036 5.498 1.819 0.0462961 gem (nuclear organelle) associated protein 5 TESK2 5.068 5.198 5.184 5.846 6.049 6.154 1.822 0.0170788 testis-specific kinase 2 GSDMA 5.893 5.67 5.478 6.359 6.758 6.357 1.822 0.0393733 gasdermin A PCDHA9 4.59 4.629 4.824 5.496 5.842 5.375 1.824 0.0232604 protocadherin alpha 9 CHPF 7.132 7.257 6.962 8.557 7.999 7.646 1.824 0.037498 chondroitin polymerizing factor C1orf84 3.535 3.563 2.327 4.379 4.027 4.431 1.825 0.0380246 chromosome 1 open reading frame 84 WFDC8 3.034 1.936 2.625 3.493 3.452 3.562 1.825 0.0431802 WAP four-disulfide core domain 8 NDUFAF4 8.469 7.346 8.14 8.927 9.008 9.225 1.826 0.0330786 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4 POLR2F 9.015 9.019 9.354 9.886 9.899 9.915 1.828 0.0309988 polymerase (RNA) II (DNA directed) polypeptide F LOC1001909 6.296 6.982 6.931 7.738 7.694 7.853 1.829 0.0200408 No description 86 LOC400043 6.916 6.391 6.731 7.252 7.86 7.603 1.83 0.0375195 No description ZNF250 6.862 6.492 6.431 7.196 7.733 7.368 1.83 0.0413193 zinc finger protein 250 PPAN 7.769 6.771 7.49 8.506 8.111 8.362 1.831 0.0404343 peter pan homolog (Drosophila) API5 8.124 7.756 7.733 8.86 8.39 9 1.835 0.0375603 apoptosis inhibitor 5 ZNF397OS 2.787 3.339 3.359 3.888 4.075 4.235 1.836 0.0313071 No description CFLP1 4.722 4.749 5.067 5.575 5.628 6.114 1.839 0.0269929 cofilin pseudogene 1 WDR85 6.441 6.505 6.213 7.385 7.156 7.212 1.84 0.0190212 WD repeat domain 85 PRDM14 6.378 5.972 5.856 6.669 7.383 6.852 1.84 0.043681 PR domain containing 14 LOC1002893 5.77 5.923 5.64 6.65 6.739 6.564 1.841 0.01611 No description 41 RNGTT 5.187 5.025 5.037 6.422 5.793 5.921 1.845 0.0221421 RNA guanylyltransferase and 5′-phosphatase NCRNA00182 9.233 8.781 8.887 9.955 9.667 9.859 1.848 0.0276111 non-protein coding RNA 182 NRCAM 3.018 3.483 3.065 4.369 3.778 4.225 1.849 0.0305509 neuronal cell adhesion molecule LIF 11.346 11.043 11.551 11.93 12.594 12.129 1.849 0.0380776 leukemia inhibitory factor (cholinergic differentiation factor) CLOCK 4.337 3.698 4.005 5.076 4.584 5.02 1.849 0.0414087 clock homolog (mouse) CNPY3 6.499 6.259 5.979 7.283 7.148 7.135 1.851 0.0183523 canopy 3 homolog (zebrafish) MRPS9 6.216 6.108 6.129 7.106 7.059 6.771 1.852 0.0224762 mitochondrial ribosomal protein S9 C10orf140 3.335 3.368 3.522 4.004 4.844 4.258 1.852 0.0315361 chromosome 10 open reading frame 140 HRAS 9.004 8.529 8.242 9.616 9.378 9.425 1.86 0.0393389 v-Ha-ras Harvey rat sarcoma viral oncogene homolog RAI1 8.961 8.626 8.834 9.67 9.915 9.523 1.862 0.0216126 retinoic acid induced 1 CCDC86 9.485 8.426 9.144 10.381 10.029 9.94 1.862 0.0288503 coiled-coil domain containing 86 WNK3 4.501 4.415 5.086 5.575 5.312 5.873 1.862 0.0397775 WNK lysine deficient protein kinase 3 CACNG4 2.522 2.477 1.936 3.647 2.802 3.373 1.862 0.0423675 calcium channel, voltage-dependent, gamma subunit 4 MOCS3 4.21 3.687 3.849 4.676 4.673 5.108 1.863 0.0311941 molybdenum cofactor synthesis 3 DGKE 7.427 6.967 7.233 8.07 8.136 8.131 1.864 0.0187143 diacylglycerol kinase, epsilon 64kDa PDGFC 4.203 4.634 4.339 5.285 5.204 5.238 1.864 0.0231874 platelet derived growth factor C FLJ42627 6.348 5.627 6.151 7.049 6.938 7.081 1.864 0.0232389 No description IL10 6.141 6.003 6.326 7.04 7.763 6.68 1.864 0.0397625 interleukin 10 MGC57346 3.351 2.834 2.747 3.686 4.25 3.725 1.864 0.0407226 No description MSL2 6.087 6.443 5.984 6.884 7.031 7.146 1.865 0.0285541 male-specific lethal 2 homolog (Drosophila) C6orf97 2.91 3.481 3.57 4.468 4.38 3.992 1.865 0.0312478 chromosome 6 open reading frame 97 GPR113 1.563 1.8 1.714 2.498 2.51 2.7 1.866 0.0157917 G protein-coupled receptor 113 NAP1L4 9.959 9.288 9.264 10.662 10.703 10.164 1.866 0.0310718 nucleosome assembly protein 1-like 4 LASS4 4.983 3.986 4.928 5.884 5.37 5.608 1.868 0.0472476 LAG1 homolog, ceramide synthase 4 ZNF431 2.235 2.025 1.926 2.927 3.651 2.696 1.869 0.0307591 zinc finger protein 431 CTDP1 7.031 6.649 6.235 7.934 7.5 7.431 1.869 0.0326887 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 RUVBL1 5.018 4.697 3.976 5.922 5.44 5.601 1.871 0.0296351 RuvB-like 1 (E. coli) ZNF767 4.631 4.892 4.855 5.76 5.874 5.223 1.872 0.0456199 zinc finger family member 767 ADSL 6.007 5.808 4.716 6.912 6.206 6.695 1.873 0.0491164 adenylosuccinate lyase MLLT10 4.226 4.364 4.189 5.15 5.146 5.097 1.876 0.0115318 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 GOT1 6.128 6.118 5.303 7.038 6.567 6.833 1.879 0.0410753 glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) SIRT3 9.393 9.011 9.195 10.105 10.198 9.977 1.88 0.0186099 sirtuin 3 C19orf10 8.715 7.95 7.757 9.627 8.603 9.357 1.882 0.0498712 chromosome 19 open reading frame 10 CRX 3.918 4.156 4.21 4.879 4.98 5.124 1.884 0.0163977 cone-rod homeobox MCPH1 4.556 4.522 4.261 5.716 5.174 5.358 1.884 0.0194384 microcephalin 1 RPUSD3 2.724 1.928 2.348 3.354 3.149 3.263 1.885 0.0335694 RNA pseudouridylate synthase domain containing 3 ZNF713 6.857 6.593 6.251 7.197 7.647 7.507 1.885 0.036007 zinc finger protein 713 SGPL1 5.855 5.92 5.464 6.837 6.244 6.774 1.887 0.041539 sphingosine-1-phosphate lyase 1 SLC19A3 3.297 2.781 2.919 3.901 3.697 4.12 1.888 0.0280017 solute carrier family 19, member 3 FHL2 10.843 11.028 10.787 11.705 11.93 11.897 1.889 0.011071 four and a half LIM domains 2 C1orf66 3.719 3.902 3.937 4.855 4.849 4.382 1.889 0.031921 chromosome 1 open reading frame 66 POLG2 4.408 4.846 4.453 5.47 5.527 5.326 1.89 0.024325 polymerase (DNA directed), gamma 2, accessory subunit MPHOSPH8 8.151 7.585 7.122 8.466 8.817 8.503 1.89 0.0413386 M-phase phosphoprotein 8 YDJC 6.698 6.492 6.565 7.673 7.256 7.484 1.891 0.0202018 YdjC homolog (bacterial) ZNF202 3.079 2.919 2.03 3.697 4.001 3.772 1.894 0.0237261 zinc finger protein 202 RAGE 5.002 4.595 5.286 6.212 5.733 5.845 1.899 0.0290234 renal tumor antigen KIAA0495 5.781 5.937 6.371 6.831 7.223 6.863 1.9 0.0271639 KIAA0495 MARVELD3 6.19 5.778 5.252 6.572 7.106 6.704 1.9 0.0301181 MARVEL domain containing 3 XPNPEP3 5.043 5.199 5.646 5.844 6.803 6.125 1.9 0.0481126 X-prolyl aminopeptidase (aminopeptidase P) 3, putative NACA 3.63 3.298 3.327 4.956 4.254 3.98 1.901 0.0393318 nascent polypeptide-associated complex alpha subunit SFRS8 7.865 7.775 8.07 9.07 8.702 8.765 1.902 0.0165486 No description NUDT22 3.71 3.789 2.719 4.716 4.194 4.45 1.902 0.0416999 nudix (nucleoside diphosphate linked moiety X)- type motif 22 ERCC1 9.204 8.714 8.854 9.998 9.783 9.78 1.903 0.0201073 excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) ORAOV1 5.885 5.373 5.541 6.473 6.473 6.412 1.907 0.0269471 oral cancer overexpressed 1 HN1L 8.928 7.892 8.765 9.846 9.697 9.574 1.908 0.020493 hematological and neurological expressed 1 -like EIF4E2 6.92 6.333 6.702 7.852 7.4 7.531 1.908 0.0272762 eukaryotic translation initiation factor 4E family member 2 ARHGEF18 4.821 4.178 4.048 5.541 4.981 5.525 1.91 0.0345167 Rho/Rac guanine nucleotide exchange factor (GEF) 18 DCLRE1C 3.838 3.427 3.518 4.647 4.772 4.284 1.911 0.0201581 DNA cross-link repair 1C KLHL36 7.469 6.691 7.281 8.404 7.784 8.217 1.912 0.0355091 kelch-like 36 (Drosophila) PLCD3 9.191 9.006 9.473 10.127 10.007 10.267 1.913 0.0208686 phospholipase C, delta 3 ISLR2 4.079 3.766 3.587 4.716 4.765 4.523 1.913 0.0281069 immunoglobulin superfamily containing leucine-rich repeat 2 REPIN1 7.861 7.741 7.81 8.893 8.746 8.648 1.914 0.0091558 replication initiator 1 PPP1R9A 2.724 2.146 2.367 3.548 3.083 3.548 1.914 0.0247836 protein phosphatase 1, regulatory (inhibitor) subunit 9A GYG2 1.143 0.464 0.251 1.188 1.758 1.827 1.915 0.0461072 glycogenin 2 C18orf25 6.441 6.646 7.099 7.425 7.591 7.584 1.916 0.0463562 chromosome 18 open reading frame 25 NLRP12 5.045 5.134 5.107 5.984 6.635 6.035 1.917 0.012019 NLR family, pyrin domain containing 12 RIOK1 7.066 7.132 6.766 8.144 7.92 7.706 1.918 0.0204393 RIO kinase 1 (yeast) CACYBP 7.506 6.93 7.119 7.831 8.447 8.12 1.919 0.0314817 calcyclin binding protein FAM23A 2.807 3.121 3.086 4.479 3.64 4.028 1.92 0.0230522 family with sequence similarity 23, member A GOLGA6C 1.62 2.812 3.3 3.753 3.946 3.742 1.92 0.0380632 golgin A6 family, member C SNRPD2 10.029 9.649 9.402 10.352 10.59 10.687 1.92 0.0388739 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa C21orf7 1.864 1.332 1.563 2.274 2.423 2.897 1.921 0.0313987 chromosome 21 open reading frame 7 ZNF485 3.525 4 3.667 4.467 5.13 4.529 1.922 0.0289705 zinc finger protein 485 SNHG4 3.654 3.413 3.026 4.356 3.968 4.624 1.923 0.034287 small nucleolar RNA host gene 4 (non-protein coding) NDNL2 6.501 6.353 6.072 7.447 7.245 7.246 1.926 0.0122823 necdin-like 2 LONP2 6.327 5.933 5.78 7.132 7.194 6.726 1.926 0.020983 Ion peptidase 2, peroxisomal HES2 3.721 3.428 2.914 4.332 4.638 4.375 1.927 0.0182779 hairy and enhancer of split 2 (Drosophila) LOC1001300 3.863 3.553 4.081 4.475 5.03 4.944 1.93 0.0245868 No description 93 INTS12 5.097 4.444 4.576 5.769 5.525 5.462 1.93 0.0365915 integrator complex subunit 12 EN2 4.848 3.057 4.601 5.597 5.55 5.467 1.931 0.0318716 engrailed homeobox 2 TMEM186 4.382 3.57 3.944 5.332 4.504 4.997 1.932 0.0447914 transmembrane protein 186 NXT2 4.042 4.065 3.503 5.016 4.526 4.827 1.934 0.0328747 nuclear transport factor 2-like export factor 2 COQ10B 3.315 3.196 3.562 4.283 4.067 4.516 1.937 0.0207219 coenzyme Q10 homolog B (S. cerevisiae) ERBB3 3.908 4.098 3.46 4.444 4.863 4.92 1.939 0.0345468 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) HS3ST3A1 5.122 4.618 5.083 6.205 5.467 6.039 1.94 0.0349839 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 NKX2-5 1.608 1.297 1.562 2.989 2.094 2.52 1.943 0.0250047 NK2 transcription factor related, locus 5 (Drosophila) LSM7 9.226 8.658 8.521 10.133 9.634 9.479 1.943 0.04089 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) RBM25 8.026 8.492 8.62 9.244 9.368 9.579 1.944 0.0182993 RNA binding motif protein 25 MACC1 4.614 4.138 4.253 5.168 5.562 5.212 1.944 0.0194241 metastasis associated in colon cancer 1 RHBDL1 5.402 5.466 5.334 6.362 6.618 6.226 1.945 0.0105931 rhomboid, veinlet-like 1 (Drosophila) CYHR1 5.824 5.136 5.123 6.472 6.784 5.893 1.945 0.0403763 cysteine/histidine-rich 1 ADIPOQ 3.058 2.926 3.118 4.012 4.019 4.021 1.947 0.0065179 adiponectin, C1Q and collagen domain containing WDR92 4.107 3.684 3.953 5.001 5.062 4.645 1.947 0.0173921 WD repeat domain 92 C12orf43 4.851 4.338 3.448 5.806 5.015 5.299 1.947 0.0425542 chromosome 12 open reading frame 43 EFCAB5 1.065 1.075 1.164 2.039 2.228 1.948 1.95 0.0093346 EF-hand calcium binding domain 5 GPR75 2.789 2.546 2.423 3.376 3.753 3.683 1.95 0.0131287 G protein-coupled receptor 75 SLC14A1 6.465 6.365 6.196 7.16 7.547 7.191 1.95 0.015894 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) NSUN5 6.908 7.471 7.029 8.167 7.909 7.993 1.95 0.0288968 NOP2/Sun domain family, member 5 CCDC141 0.871 1.044 1.301 2.417 1.616 2.008 1.95 0.0356199 coiled-coil domain containing 141 MBIP 4.88 5.018 5.235 5.807 5.982 6.212 1.951 0.0170716 MAP3K12 binding inhibitory protein 1 ZNF321 6.88 6.166 6.765 7.442 7.846 7.308 1.952 0.0401259 zinc finger protein 321 UTP15 5.412 5.821 5.45 6.71 6.378 6.726 1.954 0.0130085 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) RECQL4 5.018 3.751 5.163 5.588 6.129 5.738 1.954 0.0417271 RecQ protein-like 4 SEC61G 7.429 7.862 8.103 9.041 8.599 8.83 1.956 0.0212685 Sec61 gamma subunit CD1D 3.145 2.983 3.357 4.114 4.387 3.832 1.956 0.0226308 CD1d molecule CCDC71 5.165 3.195 4.69 6.133 5.592 5.554 1.956 0.0360213 coiled-coil domain containing 71 ZNF721 5.646 4.931 5.844 6.514 6.384 6.812 1.957 0.0239243 zinc finger protein 721 SETD1A 8.391 7.337 7.909 9.267 8.877 8.745 1.957 0.0309108 SET domain containing 1A MTIF2 4.166 3.89 3.984 5.129 4.953 4.878 1.958 0.0109859 mitochondrial translational initiation factor 2 MDN1 5.221 4.986 5.174 6.391 5.955 6.045 1.958 0.0133319 MDN1, midasin homolog (yeast) DEAF1 7.636 6.893 7.309 8.279 8.531 8.151 1.958 0.0206825 deformed epidermal autoregulatory factor 1 (Drosophila) AATK 4.689 4.173 3.567 5.142 5.322 4.915 1.958 0.0458618 apoptosis-associated tyrosine kinase BRI3BP 2.073 2.257 1.126 3.227 2.994 2.439 1.958 0.0473213 BRI3 binding protein PLEKHJ1 6.438 6.283 6.473 7.456 7.408 7.086 1.959 0.0167811 pleckstrin homology domain containing, family J member 1 RBBP9 4.812 4.137 4.745 5.564 5.784 5.607 1.961 0.0156636 retinoblastoma binding protein 9 NPC1L1 4.029 4.466 4.42 5.088 5.438 5.311 1.961 0.017669 NPC1 (Niemann-Pick disease, type C1, gene)-like 1 TAF3 7.282 7.329 6.178 8.301 8.247 8.042 1.961 0.019819 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa PM20D2 5.041 5.535 5.655 6.626 6.233 6.271 1.961 0.0259855 peptidase M20 domain containing 2 TIGD6 3.898 3.387 3.489 4.619 4.416 4.461 1.962 0.0229835 tigger transposable element derived 6 NHEJ1 5.031 3.903 4.656 5.629 5.862 5.527 1.963 0.0253445 nonhomologous end-joining factor 1 CDK16 9.634 8.997 9.315 10.371 10.289 10.078 1.964 0.0263325 cyclin-dependent kinase 16 POLG 8.252 7.398 8.419 9.002 9.395 9.036 1.966 0.0266187 polymerase (DNA directed), gamma ACBD7 2.901 2.688 3.022 3.877 3.621 4.012 1.967 0.0157487 acyl-CoA binding domain containing 7 ZNF44 5.211 5.131 4.997 5.775 6.192 6.107 1.967 0.0188767 zinc finger protein 44 SNORA72 3.978 3.292 3.4 4.775 4.268 4.668 1.967 0.0264849 small nucleolar RNA, H/ACA box 72 LOC646851 5.964 5.601 5.616 6.623 6.771 6.578 1.968 0.0161437 No description F5 8.333 8.68 8.642 9.31 9.539 9.707 1.968 0.0166037 coagulation factor V (proaccelerin, labile factor) MAOA 4.498 4.26 2.527 5.237 5.256 5.148 1.968 0.0317786 monoamine oxidase A CWC25 7.85 7.88 7.522 8.858 8.581 8.691 1.969 0.0150733 CWC25 spliceosome-associated protein homolog (S. cerevisiae) UCKL1 7.36 7.027 7.502 8.453 8.353 8.006 1.971 0.0203785 uridine-cytidine kinase 1-like 1 SFRS16 8.123 8.089 8.563 9.407 9.068 9.134 1.971 0.021853 No description IYD 3.918 4.294 3.586 5.073 5.172 4.565 1.972 0.029937 iodotyrosine deiodinase BRD4 9.511 9.562 9.446 10.491 10.571 10.264 1.973 0.0118809 bromodomain containing 4 ZNF737 5.788 5.497 4.974 6.478 6.602 6.28 1.973 0.0231745 zinc finger protein 737 CDK20 5.184 4.509 4.432 5.717 5.413 5.796 1.974 0.0375338 cyclin-dependent kinase 20 CRELD2 5.576 5.085 4.649 6.288 5.797 6.066 1.974 0.0431445 cysteine-rich with EGF-like domains 2 TSTD1 5.59 5.75 3.89 6.717 6.507 6.572 1.975 0.0237812 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 ATP6V1D 8.415 7.321 7.838 8.882 8.82 8.789 1.975 0.0418995 ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D ZFP36L1 12.183 11.334 11.768 12.752 13.004 12.725 1.978 0.0210932 zinc finger protein 36, C3H type-like 1 FLJ39582 3.512 1.759 3.211 4.359 4.196 3.947 1.98 0.0339536 No description KCTD13 6.258 6.208 6.351 7.633 7.244 7.117 1.981 0.0111369 potassium channel tetramerisation domain containing 13 C20orf96 3.608 3.54 4.343 5.128 5.001 4.526 1.981 0.0301252 chromosome 20 open reading frame 96 ZNF192 3.758 3.908 3.953 4.532 5.124 4.895 1.982 0.0186392 zinc finger protein 192 UCKL1AS 3.329 2.765 2.931 4.282 3.918 3.772 1.982 0.0238778 No description MPP6 6.728 6.382 6.584 7.752 7.37 7.437 1.983 0.0169643 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) CCDC113 1.837 2.059 2.235 3.116 3.222 2.453 1.983 0.0459376 coiled-coil domain containing 113 TRMU 5.968 5.961 5.85 7.469 6.841 6.931 1.986 0.0099077 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase SUPT4H1 7.011 6.264 6.605 7.635 7.596 7.564 1.987 0.0236717 suppressor of Ty 4 homolog 1 (S. cerevisiae) LIAS 4.897 4.328 4.699 5.102 6.023 5.689 1.987 0.0433691 lipoic acid synthetase E2F5 5.459 5.709 5.914 6.846 6.603 6.7 1.988 0.011901 E2F transcription factor 5, p130-binding ATF2 5.699 4.675 5.217 6.064 6.258 6.208 1.988 0.0375052 activating transcription factor 2 SHANK2 2.298 2.995 3.543 3.987 3.953 4.001 1.988 0.0406804 SH3 and multiple ankyrin repeat domains 2 STYXL1 3.763 3.169 2.187 4.115 4.16 4.27 1.988 0.0437712 serine/threonine/tyrosine interacting-like 1 ZNF91 1.228 2.008 2.466 2.999 3.434 2.593 1.988 0.0439028 zinc finger protein 91 SBNO2 9.873 9.232 9.773 10.868 10.585 10.293 1.993 0.0328604 strawberry notch homolog 2 (Drosophila) RNF166 4.176 3.326 4.883 5.489 5.091 5.172 1.993 0.047395 ring finger protein 166 PARD6G 6.221 5.99 5.99 6.986 7.37 6.885 1.994 0.0142684 par-6 partitioning defective 6 homolog gamma (C. elegans) CCT2 10.422 9.653 10.006 11.193 10.89 11.001 1.994 0.0239908 chaperonin containing TCP1, subunit 2 (beta) RAD51L3 3.817 2.864 3.289 4.285 4.442 4.197 1.994 0.0336345 RAD51-like 3 (S. cerevisiae) ARHGEF33 1.748 2.048 1.818 3.209 2.8 2.745 1.996 0.0127738 Rho guanine nucleotide exchange factor (GEF) 33 NR2C2AP 4.898 3.66 4.683 5.891 5.68 5.669 1.997 0.0163855 nuclear receptor 2C2-associated protein SCN11A 5.51 5.097 4.982 5.98 6.298 6.112 1.997 0.0228819 sodium channel, voltage-gated, type XI, alpha subunit NCAPG 0.589 1.126 1.421 2.157 1.92 2.124 1.997 0.0241754 non-SMC condensin I complex, subunit G YLPM1 5.552 5.118 5.146 6.16 6.117 6.396 1.998 0.0185276 YLP motif containing 1 NEURL4 6.201 5.35 5.613 6.493 6.612 6.811 1.999 0.0406482 neuralized homolog 4 (Drosophila) ABCF1 8.571 8.103 7.891 9.406 8.891 9.263 2 0.0265779 ATP-binding cassette, sub-family F (GCN20), member 1 UPP2 5.108 4.587 4.954 6.21 5.864 5.588 2.001 0.0234027 uridine phosphorylase 2 CTSC 7.03 6.652 6.904 8.11 7.485 7.905 2.001 0.0234864 cathepsin C CEP192 4.34 4.409 4.456 5.411 6.146 4.856 2.003 0.0382063 centrosomal protein 192kDa POLE 6.218 5.676 5.679 6.866 6.743 6.679 2.004 0.0268598 polymerase (DNA directed), epsilon CTU1 7.068 6.377 6.169 7.593 7.381 7.373 2.006 0.0447399 cytosolic thiouridylase subunit 1 homolog (S. pombe) LOC1002926 2.972 3.285 2.439 3.447 4.289 3.896 2.006 0.0469192 No description 80 NAT10 8.556 7.438 8.027 9.562 8.789 8.902 2.008 0.0423303 N-acetyltransferase 10 (GCN5-related) DPP3 4.908 4.086 4.722 5.915 5.492 5.425 2.01 0.0282156 dipeptidyl-peptidase 3 LOC390595 5.916 5.154 5.429 6.408 6.777 6.437 2.011 0.0221213 No description C1orf162 2.241 2.357 1.44 3.365 2.812 3.022 2.011 0.0324247 chromosome 1 open reading frame 162 SPAG5 4.773 3.161 4.477 5.339 5.783 5.484 2.013 0.0237054 sperm associated antigen 5 RPL35 13.834 13.033 13.62 14.844 14.377 14.416 2.014 0.0254897 ribosomal protein L35 VAMP8 6.996 7.462 6.998 8.007 8.203 8.102 2.015 0.0185419 vesicle-associated membrane protein 8 (endobrevin) ZNF547 2.189 1.488 1.435 2.625 2.446 3.088 2.015 0.0338671 zinc finger protein 547 MBLAC1 4.051 3.743 3.809 4.758 5.022 4.952 2.021 0.008871 metallo-beta-lactamase domain containing 1 ZNF280C 4.279 3.849 3.457 5.294 4.656 4.53 2.021 0.0468048 zinc finger protein 280C SFXN2 2.807 2.903 2.844 4.252 3.755 3.859 2.022 0.0086585 sideroflexin 2 TRIP13 4.181 4.158 4.068 5.35 5.174 4.793 2.022 0.0174351 thyroid hormone receptor interactor 13 C14orf176 3.418 2.766 3.331 4.526 3.762 4.346 2.022 0.0305309 chromosome 14 open reading frame 176 ZNF749 1.243 1.246 1.182 2.26 2.268 1.676 2.023 0.0375674 zinc finger protein 749 PCNXL3 7.225 6.713 6.737 7.859 7.73 8.036 2.025 0.0189011 pecanex-like 3 (Drosophila) LIME1 4.704 3.721 4.211 5.366 5.229 5.22 2.025 0.0252501 Lek interacting transmembrane adaptor 1 TRIM68 0.68 1.494 1.038 2.313 1.699 2.382 2.026 0.0301846 tripartite motif-containing 68 EXOC3 7.076 6.101 6.32 7.644 7.326 7.338 2.026 0.0471324 exocyst complex component 3 RCCD1 5.047 4.618 4.501 5.939 6.066 5.508 2.027 0.0150032 RCC1 domain containing 1 STRN4 8.858 7.477 8.484 9.521 9.503 9.161 2.027 0.0405645 striatin, calmodulin binding protein 4 GOLGA3 7.632 7.437 6.97 8.637 8.29 8.457 2.028 0.0135158 golgin A3 ASZ1 3.902 4.446 4.067 4.964 5.467 5.085 2.029 0.0188045 ankyrin repeat, SAM and basic leucine zipper domain containing 1 C10orf12 1.632 1.767 2.439 3.259 2.653 2.978 2.029 0.0327402 chromosome 10 open reading frame 12 STARD10 6.616 5.753 6.198 6.859 7.309 7.22 2.03 0.0404143 StAR-related lipid transfer (START) domain containing 10 RBBP5 4.76 4.222 3.366 4.95 5.244 5.666 2.031 0.0385576 retinoblastoma binding protein 5 C19orf46 5.618 5.708 5.289 6.962 6.606 6.312 2.032 0.0157273 chromosome 19 open reading frame 46 CCR6 3.921 3.414 3.889 4.439 5.484 4.823 2.034 0.0225749 chemokine (C-C motif) receptor 6 FLJ45340 6.401 5.737 6.033 6.934 7.426 6.762 2.034 0.0321192 No description KDM4A 6.481 5.689 5.707 7.129 7.033 6.715 2.036 0.0323217 lysine (K)-specific demethylase 4A RNF126P1 7.269 7.01 7.018 8.392 8.044 7.937 2.037 0.0129942 ring finger protein 126 pseudogene 1 RRAGO 7.582 6.404 7.04 8.154 8.066 7.999 2.037 0.0333491 Ras-related GTP binding C HOMER3 5.319 5.839 4.955 6.346 6.178 6.416 2.037 0.0362753 homer homolog 3 (Drosophila) C15orf40 4.189 4.466 4.22 5.487 5.282 5.217 2.039 0.0089168 chromosome 15 open reading frame 40 SETD4 4.735 4.221 5.209 6.017 5.58 5.763 2.039 0.0283194 SET domain containing 4 SCARF2 5.198 4.924 4.283 5.953 5.937 6.138 2.04 0.0136875 scavenger receptor class F, member 2 CYP27B1 5.891 5.464 5.878 7.03 6.492 6.839 2.04 0.0169428 cytochrome P450, family 27, subfamily B, polypeptide 1 CELSR3 3.642 3.7 4.3 4.35 5.329 4.937 2.041 0.0463032 cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila) CLDN15 6.315 4.142 5.876 6.907 7.336 6.604 2.044 0.0362059 claudin 15 NOP2 7.033 7.76 7.419 8.052 8.793 8.608 2.046 0.0260363 NOP2 nucleolar protein homolog (yeast) SAPS3 8.809 8.193 7.866 9.266 9.226 9.097 2.046 0.0455398 No description YJEFN3 2.658 2.743 2.949 3.983 3.613 3.806 2.048 0.0111927 YjeF N-terminal domain containing 3 TMEM216 4.046 4.112 4.689 5.153 5.132 5.147 2.048 0.0361937 transmembrane protein 216 CACNA1I 1.03 1.408 0.912 2.064 2.258 1.975 2.049 0.0168627 calcium channel, voltage-dependent, T type, alpha 11 subunit TIMM13 8.745 7.721 8.187 9.555 9.223 9.001 2.05 0.035195 translocase of inner mitochondrial membrane 13 homolog (yeast) GGT7 7.584 7.051 7.612 8.843 8.186 8.087 2.05 0.0409165 gamma-glutamyltransferase 7 C10orf125 4.003 3.526 3.082 5.039 4.973 3.893 2.05 0.0495328 chromosome 10 open reading frame 125 LOC389765 1.037 0.162 0.498 0.924 2.073 2.008 2.051 0.0476798 No description KIAA1875 9.192 8.836 9.273 10.009 10.312 9.963 2.054 0.0162267 KIAA1875 EXOSC9 4.554 4.489 4.399 5.656 5.439 5.45 2.055 0.0065393 exosome component 9 PSMD5 4.889 4.911 4.382 5.514 5.95 5.766 2.055 0.0193761 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 PYCR1 6.547 6.334 6.159 7.665 7.199 7.347 2.057 0.0126644 pyrroline-5-carboxylate reductase 1 MPL 4.562 3.154 3.724 5.155 4.737 4.765 2.058 0.0484331 myeloproliferative leukemia virus oncogene IDH3A 7.52 7.045 7.007 8.438 8.168 8.05 2.059 0.0169836 Description C19orf44 4.502 3.247 4.206 5.544 5.236 5.128 2.059 0.0181491 chromosome 19 open reading frame 44 RFPL1S 4.052 4.463 4.067 5.531 5.108 4.894 2.059 0.0245646 RFPL1 antisense RNA (non-protein coding) EIF2S2 9.717 9.743 9.079 10.785 10.333 10.439 2.06 0.0263254 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa MCRS1 4.501 4.148 4.467 6.002 5.407 5.193 2.062 0.0152057 microspherule protein 1 ANKRD13D 6.652 6.065 5.949 7.11 7.318 7.035 2.064 0.0313207 ankyrin repeat domain 13 family, member D HIATL2 4.307 4.544 4.235 4.975 5.353 5.638 2.065 0.0244952 hippocampus abundant transcript-like 2 DDX18 9.02 8.306 8.653 10.068 9.421 9.689 2.067 0.0233126 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 GIGYF1 8.532 8.362 9.012 9.537 9.596 9.58 2.068 0.0242913 GRB10 interacting GYF protein 1 SPATA5 4.436 4.271 4.461 5.891 5.285 5.485 2.069 0.0087043 spermatogenesis associated 5 FCF1 7.437 7.306 7.069 8.17 8.487 8.316 2.07 0.0098304 FCF1 small subunit (SSU) processome component homolog (S. cerevisiae) HSCB 6.938 6.246 6.54 7.416 7.988 7.431 2.072 0.0257301 HscB iron-sulfur cluster co-chaperone homolog (E. coli) LOC1002165 4.173 3.818 4.58 4.952 5.631 4.968 2.072 0.0378021 No description 45 C21orf49 4.84 5.428 5.118 6.401 6.09 6.169 2.073 0.0121213 chromosome 21 open reading frame 49 DPH3B 1.826 0.78 1.998 2.85 3.051 2.54 2.075 0.0215533 No description KRT80 5.063 4.184 4.288 5.306 5.856 5.341 2.075 0.041622 keratin 80 ELAVL3 3.144 3.059 2.984 3.598 4.266 4.113 2.077 0.0270001 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) AACS 2.964 2.36 2.144 3.295 3.415 3.467 2.077 0.0392681 acetoacetyl-CoA synthetase RPL38 12.702 11.879 12.419 13.476 13.365 13.62 2.08 0.0142828 ribosomal protein L38 C3orf62 6.239 5.548 5.821 6.843 6.973 6.878 2.081 0.0172977 chromosome 3 open reading frame 62 ZBED4 5.975 5.593 5.609 7.033 6.231 6.714 2.081 0.037282 zinc finger, BED-type containing 4 ZNF274 7.134 6.233 7.085 7.971 8.191 8.128 2.082 0.0117894 zinc finger protein 274 GPC5 0.478 0.666 0.619 1.407 1.678 2.52 2.084 0.0151191 glypican 5 KDM6B 11.711 10.082 11.001 12.062 12.285 11.93 2.086 0.0448229 lysine (K)-specific demethylase 6B TFAP4 4.048 4.452 4.176 5.898 5.216 5.11 2.088 0.0145832 transcription factor AP-4 (activating enhancer binding protein 4) ZNF181 3.252 2.774 2.724 3.787 4.227 3.857 2.089 0.0179116 zinc finger protein 181 USP37 5.66 4.95 4.681 6.012 6.483 5.864 2.089 0.0397353 ubiquitin specific peptidase 37 GINS1 3.856 2.548 3.259 4.868 4.322 4.277 2.09 0.0238084 GINS complex subunit 1 (Psf1 homolog) ACSS1 4.695 4.017 4.781 5.759 5.762 5.083 2.09 0.0347578 acyl-CoA synthetase short-chain family member 1 SRCIN1 3.259 3.358 3.432 4.792 4.422 4.142 2.091 0.011765 SRC kinase signaling inhibitor 1 B3GNT4 1.885 2.108 1.44 3.093 3.057 2.504 2.091 0.0220019 UDP-GlcNAc:betaGal beta-1,3-N- acetylglucosaminyltransferase 4 NANOS1 5.942 5.654 5.142 6.719 6.732 6.703 2.092 0.0134485 nanos homolog 1 (Drosophila) FBXO25 4.507 4.51 4.238 5.647 5.254 5.573 2.093 0.0097031 F-box protein 25 KLHL17 4.942 5.261 5.803 6.737 6.326 6.147 2.093 0.0270852 kelch-like 17 (Drosophila) MPHOSPH6 6.092 6.111 5.606 7.74 6.672 7.155 2.094 0.0174909 M-phase phosphoprotein 6 LOC728190 5.578 4.722 4.883 6.368 5.789 6.124 2.095 0.0318645 No description HSF2BP 1.949 1.976 0.912 2.466 3.043 2.726 2.095 0.0322609 heat shock transcription factor 2 binding protein PHRF1 8.573 7.219 7.779 8.956 8.847 8.829 2.097 0.0498891 PHD and ring finger domains 1 ERICH1 5.957 5.849 5.266 7.024 6.807 6.918 2.098 0.0088445 glutamate-rich 1 ATP6VOD2 6.688 6.176 6.125 7.194 7.628 7.466 2.098 0.0142956 ATPase, H+ transporting, lysosomal 38kDa, VO subunit d2 PAQR5 3.016 3.717 2.735 4.281 4.219 3.805 2.099 0.0488302 progestin and adipoQ receptor family member V C1orf106 3.855 4.928 5.355 6.338 5.914 5.998 2.1 0.020895 chromosome 1 open reading frame 106 C17orf63 6.519 6.136 6.118 7.598 7.131 7.207 2.101 0.0146577 chromosome 17 open reading frame 63 FAM50B 4.02 3.21 3.389 4.739 4.516 4.282 2.102 0.034194 family with sequence similarity 50, member B ATPAF1 5.58 4.551 4.923 6.522 5.995 5.755 2.102 0.0380704 ATP synthase mitochondrial F1 complex assembly factor 1 MRAP2 4.366 3.964 4.088 5.303 5.17 5.037 2.103 0.0108421 melanocortin 2 receptor accessory protein 2 PIGM 4.256 3.893 3.567 5.328 4.442 5.24 2.103 0.0296938 phosphatidylinositol glycan anchor biosynthesis, class M PDDC1 4.081 4.473 4.967 5.548 5.75 5.199 2.106 0.035924 Parkinson disease 7 domain containing 1 MSH 8.427 8.034 7.937 9.012 9.467 9.221 2.108 0.0121628 musashi homolog 1 (Drosophila) GOLIM4 4.797 4.222 4.74 5.492 5.299 6.043 2.11 0.02915 golgi integral membrane protein 4 RAVER2 3.808 4.375 4.274 4.902 5.453 5.303 2.112 0.0185204 ribonucleoprotein, PTB-binding 2 ZC3H4 5.826 5.978 5.44 6.709 7.008 6.905 2.113 0.0098376 zinc finger CCCH-type containing 4 NCS1 8.41 7.988 8.618 9.672 9.49 9.417 2.114 0.0086778 neuronal calcium sensor 1 RARS2 4.689 3.928 3.847 5.151 4.928 5.287 2.115 0.036716 arginyl-tRNA synthetase 2, mitochondrial PPP1R3E 3.722 3.314 3.698 4.395 4.812 4.498 2.116 0.0176232 protein phosphatase 1, regulatory (inhibitor) subunit 3E ZCCHC10 4.756 4.276 3.779 5.586 4.881 5.357 2.116 0.0435515 zinc finger, COHO domain containing 10 SF3B5 10.333 9.448 9.643 11.121 10.531 10.808 2.119 0.0358067 splicing factor 3b, subunit 5, 10kDa PRKCZ 6.388 6.328 6.489 7.573 7.401 7.56 2.12 0.0042727 protein kinase C, zeta DAK 6.032 6.131 5.726 7.216 6.711 7.148 2.121 0.0146247 dihydroxyacetone kinase 2 homolog (S. cerevisiae) RHEBL1 3.933 3.958 3.692 4.235 5.575 5.018 2.121 0.0407634 Ras homolog enriched in brain like 1 OTUD5 8.449 7.376 7.767 8.853 9.195 8.708 2.122 0.0349767 OTU domain containing 5 RNF20 4.364 3.484 3.305 5.403 4.7 4.39 2.122 0.0445797 ring finger protein 20 TMC4 3.661 3.532 2.957 4.043 5.214 4.565 2.123 0.0251878 transmembrane channel-like 4 EID3 5.729 5.545 5.411 6.374 6.704 6.816 2.124 0.0106632 EP300 interacting inhibitor of differentiation 3 STX10 1.334 1.513 0.888 1.949 3.121 2.421 2.124 0.0213021 syntaxin 10 PRICKLES 3.678 3.475 4.154 5.448 4.75 4.562 2.124 0.0232124 prickle homolog 3 (Drosophila) MTPAP 8.991 8.37 8.937 9.938 10.078 9.895 2.125 0.0084725 mitochondrial poly(A) polymerase MDFI 7.121 7.083 7.719 8.537 8.171 8.443 2.125 0.0170645 MyoD family inhibitor ESRRA 8.54 7.704 7.794 9.61 8.882 8.877 2.125 0.0305652 estrogen-related receptor alpha ABRA 3.762 3.647 3.237 5.027 4.734 3.957 2.125 0.0416041 actin-binding Rho activating protein LYPD3 8.158 7.495 5.484 8.584 8.806 8.404 2.126 0.0464814 LY6/PLAUR domain containing 3 TRABD 9.07 8.838 8.748 10.198 9.838 9.851 2.129 0.0096151 TraB domain containing FAM83A 6.273 6.298 6.614 7.177 7.705 7.467 2.13 0.0138878 family with sequence similarity 83, member A C6orf145 10.308 9.415 10.016 10.91 11.314 11.107 2.131 0.0150104 chromosome 6 open reading frame 145 SSRP1 8.88 7.713 8.239 9.727 9.331 9.288 2.131 0.0252078 structure specific recognition protein 1 DUSP28 3.651 2.163 2.867 3.958 4.169 3.951 2.131 0.0403477 dual specificity phosphatase 28 KRBA2 6.382 5.533 6.244 7.1 7.474 7.12 2.132 0.0162195 KRAB-A domain containing 2 RNF185 6.18 6.073 6.409 7.473 7.167 7.418 2.134 0.0066609 ring finger protein 185 SNRPF 8.774 8.427 8.411 9.868 9.465 9.725 2.135 0.0079452 small nuclear ribonucleoprotein polypeptide F RIN1 3.09 3.389 2.495 4.185 4.465 4.053 2.135 0.0127531 Ras and Rab interactor 1 LOC283914 4.157 3.606 3.564 4.659 4.855 5.191 2.136 0.015361 No description RPS15A 10.403 10.303 10.91 11.398 11.719 11.649 2.136 0.0165966 ribosomal protein S15a CAMKK1 3.801 2.251 3.934 4.545 4.897 4.912 2.138 0.0238492 calcium/calmodulin-dependent protein kinase kinase 1. alpha ARL5A 8.188 7.178 7.873 8.981 8.969 8.909 2.139 0.0155691 ADP-ribosylation factor-like 5A DHX35 0.986 1.037 1.386 3.157 2.126 2.083 2.139 0.0158239 DEAH (Asp-Glu-Ala-His) box polypeptide 35 SPEN 10.39 9.61 9.879 10.773 11.189 10.977 2.14 0.0250118 spen homolog, transcriptional regulator (Drosophila) NOC4L 7.791 6.65 7.391 8.89 8.174 8.34 2.142 0.0277864 nucleolar complex associated 4 homolog (S. cerevisiae) EI24 8.345 7.442 7.793 8.893 8.635 9.047 2.143 0.032444 etoposide induced 2.4 mRNA CECR7 3.207 3.112 2.824 3.539 4.212 4.322 2.144 0.031886 cat eye syndrome chromosome region, candidate 7 (non-protein coding) CENPL 3.588 4.243 3.118 4.689 4.596 4.834 2.146 0.0326343 centromere protein L ZNF34 5.928 6.097 4.804 7.104 7.031 6.628 2.147 0.0217243 zinc finger protein 34 SDCCAG3 7.632 7.701 8.134 9.163 8.81 8.736 2.148 0.0140073 serologically defined colon cancer antigen 3 AARS 6.473 5.958 5.646 7.136 6.958 7.061 2.148 0.0226873 alanyl-tRNA synthetase GRIN2A 2.17 2.26 2.158 2.73 3.983 3.273 2.148 0.0287236 glutamate receptor, ionotropic, N-methyl D- aspartate 2A FUBP1 8.785 6.746 8.009 9.112 9.52 9.067 2.148 0.0369707 far upstream element (FUSE) binding protein 1 TECRL 4.758 3.642 4.234 5.74 4.745 5.393 2.148 0.0478114 trans-2,3-enoyl-CoA reductase-like SUPT3H 4.074 3.49 3.377 4.623 4.667 4.482 2.151 0.0279888 suppressor of Ty 3 homolog (S. cerevisiae) GIT1 6.113 5.509 5.564 6.943 6.614 7.087 2.152 0.01303 G protein-coupled receptor kinase interacting ArGAP 1 PWWP2A 5.523 4.037 5.079 6.185 6.281 6.045 2.152 0.0248222 PWWP domain containing 2A ATAD3A 8.453 7.672 7.875 9.057 8.995 8.778 2.152 0.032703 ATPase family, AAA domain containing 3A BCAM 7.264 6.699 6.499 7.805 8.084 7.746 2.153 0.0205473 basal cell adhesion molecule (Lutheran blood group) XPO4 4.638 4.708 5.015 6.186 5.745 5.79 2.154 0.0099921 exportin 4 C2orf76 3.779 2.947 3.364 4.886 4.271 4.455 2.154 0.0177134 chromosome 2 open reading frame 76 PSMG3 6.954 6.615 6.333 7.724 8.12 7.228 2.158 0.0296222 proteasome (prosome, macropain) assembly chaperone 3 MSTO2P 3.451 3.955 4.409 5.065 4.89 5.151 2.159 0.0217314 misato homolog 2 pseudogene SFXN1 3.047 3.352 3.434 4.475 4.545 4.012 2.16 0.0148558 sideroflexin 1 SAPS2 6.821 6.436 7.063 8.187 7.918 7.547 2.16 0.0176762 No description CNOT1 6.267 6.462 7.038 7.221 8.149 7.744 2.16 0.029193 CCR4-NOT transcription complex, subunit 1 IL12RB2 0.924 1.305 0.994 2.838 1.738 2.106 2.161 0.0238993 interleukin 12 receptor, beta 2 MOG 1.847 1.241 0.543 2.913 2.352 1.864 2.161 0.0441812 myelin oligodendrocyte glycoprotein PDIA3 5.892 5.848 5.941 7.005 8.057 6.623 2.162 0.019927 protein disulfide isomerase family A, member 3 C7orf29 3.427 3.456 2.96 5.193 4.238 4.072 2.162 0.023274 chromosome 7 open reading frame 29 LOC1001339 3.999 3.595 3.812 4.708 5.362 4.871 2.163 0.0109788 No description 57 DHX34 5.495 4.906 4.647 5.676 6.609 6.028 2.164 0.0348802 DEAN (Asp-Glu-Ala-His) box polypeptide 34 HSP90B1 7.909 9.464 8.909 9.981 10.038 10.024 2.165 0.0292946 heat shock protein 90kDa beta (Grp94), member 1 PANX2 3.994 4.614 4.315 5.431 5.564 5.237 2.166 0.0124025 pannexin 2 DDX31 5.384 6.407 5.927 6.829 7.093 7.042 2.167 0.0257158 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 KIAA1530 4.327 5.181 4.914 6.297 5.942 6.003 2.168 0.0103856 KIAA1530 SRCAP 6.83 6.603 7.291 7.719 8.384 8.221 2.168 0.0145761 Snf2-related CREBBP activator protein CELF1 7.086 6.671 6.689 8.203 7.752 7.907 2.169 0.009799 CUGBP, Elav-like family member 1 ZNF625 5.086 5.14 4.828 6.162 6.3 5.946 2.17 0.0073557 zinc finger protein 625 LOC1002943 8.693 8.135 8.335 9.454 9.65 9.388 2.172 0.0103499 No description 62 PCGF2 8.219 7.18 7.557 8.708 8.822 8.299 2.172 0.049902 polycomb group ring finger 2 TUBGCP4 3.95 3.303 3.329 4.829 4.423 4.641 2.174 0.0161923 tubulin, gamma complex associated protein 4 ALX3 2.956 2.861 1.315 4.076 3.556 3.601 2.174 0.0315969 ALX homeobox 3 METTL12 1.424 2.888 2.665 4.008 3.56 3.282 2.174 0.0317135 methyltransferase like 12 C4orf43 4.011 3.68 3.29 5.207 4.1 4.802 2.175 0.0442477 chromosome 4 open reading frame 43 TTF2 3.684 3.788 4.581 4.955 4.909 4.881 2.175 0.047976 transcription termination factor, RNA polymerase II LOC647979 7.522 7.205 7.547 8.643 8.289 8.872 2.176 0.0092366 No description ZNF780B 2.891 3.251 3.694 4.483 4.373 4.227 2.176 0.017888 zinc finger protein 780B HS3ST2 3.601 4.459 1.429 5.378 4.631 4.722 2.176 0.0418051 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 C20orf12 3.149 1.536 2.596 3.915 3.718 3.217 2.176 0.0465336 chromosome 20 open reading frame 12 C22orf30 4.992 4.244 4.551 6.114 5.378 5.458 2.177 0.0305137 chromosome 22 open reading frame 30 KIAA0664 9.002 8.446 9.511 10.244 10.126 10.055 2.178 0.0201002 KIAA0664 PPHLN1 7.595 8.338 7.651 8.774 8.785 8.772 2.178 0.0347972 periphilin 1 CACNA1A 3.059 3.149 2.524 3.647 4.334 3.684 2.178 0.0367439 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit SAMD1 5.64 5.016 4.631 5.608 7.046 6.139 2.178 0.0489225 sterile alpha motif domain containing 1 MYL7 3.609 4.912 4.611 5.734 5.679 6.021 2.179 0.0130758 myosin, light chain 7, regulatory BRD9 7.865 7.024 7.74 8.989 8.726 8.626 2.18 0.0124827 bromodomain containing 9 DMWD 7.048 6.29 6.462 7.714 7.665 7.415 2.18 0.0258153 dystrophia myotonica, WD repeat containing LOC26080 1.513 1.715 1.301 2.638 2.782 2.493 2.182 0.0072813 No description PPAPDC2 3.727 4.528 4.431 6.117 4.848 5.556 2.182 0.0259712 phosphatidic acid phosphatase type 2 domain containing 2 IL20RB 1.66 2.142 1.075 2.515 3.269 2.777 2.183 0.0221492 interleukin 20 receptor beta EP300 8.06 7.573 8.197 8.7 9.274 9.279 2.184 0.016618 E1A binding protein p300 STMN1 8.863 7.929 8.786 9.056 10.015 9.657 2.184 0.047855 stathmin 1 KIAA1919 4.956 4.005 4.679 5.987 5.35 5.808 2.187 0.0222279 KIAA1919 LAT 4.363 3.94 4.208 5.133 5.87 5.07 2.189 0.0153996 linker for activation of T cells PTPN23 7.908 7.259 7.594 9.264 8.505 8.39 2.189 0.0242362 protein tyrosine phosphatase, non-receptor type 23 HSF1 10.009 9.31 9.478 10.787 10.44 10.635 2.19 0.0213343 heat shock transcription factor 1 BET1L 5.526 4.895 4.852 6.294 6.027 5.997 2.191 0.022512 blocked early in transport 1 homolog (S. cerevisiae)- like BHMT2 5.862 5.795 5.491 6.771 6.996 6.665 2.194 0.008758 betaine homocysteine S-methyltransferase 2 PLCB3 3.94 3.303 3.071 4.627 4.437 4.426 2.194 0.0225993 phospholipase C, beta 3 (phosphatidylinositol- specific) ZNF341 4.241 2.483 3.787 5.374 4.643 4.814 2.194 0.0271238 zinc finger protein 341 HOXA9 5.212 4.626 4.223 6.326 5.637 5.76 2.195 0.0201789 homeobox A9 TMEM120B 5.301 5.65 6.467 7.421 6.68 6.785 2.196 0.0339465 transmembrane protein 120B LOC728606 4.446 4.539 4.132 5.296 5.675 5.297 2.197 0.0130014 No description KIAA0226 4.956 5.51 4.843 6.513 5.972 6.647 2.2 0.0114803 KIAA0226 NPM3 7.542 7.266 7.509 8.981 8.634 8.405 2.203 0.0065894 nucleophosmin/nucleoplasmin 3 ZNF692 5.125 5.739 5.653 6.513 6.878 6.635 2.203 0.010709 zinc finger protein 692 ZNF75A 1.03 1.141 1.52 2.281 2.171 2.619 2.203 0.0111712 zinc finger protein 75a CPSF7 9.397 7.659 9.095 10.283 10.235 9.773 2.203 0.0309179 cleavage and polyadenylation specific factor 7, 59kDa CHI3L1 2.843 5.136 4.666 5.216 6.275 5.682 2.203 0.0446362 chitinase 3-like 1 (cartilage glycoprotein-39) MED10 6.502 5.776 6.217 7.642 7.097 7.256 2.204 0.0148193 mediator complex subunit 10 INO80E 7.11 5.593 6.513 8.004 7.596 7.654 2.205 0.0221085 INO80 complex subunit E C2orf81 5.238 5.22 5.09 6.212 6.361 6.501 2.206 0.0039501 chromosome 2 open reading frame 81 C21orf88 6.171 5.605 6.126 6.954 7.404 6.747 2.207 0.0215103 chromosome 21 open reading frame 88 LOC645676 4.104 3.017 3.233 4.159 4.878 4.557 2.207 0.0399077 No description CCDC123 4.762 3.591 3.943 4.962 5.36 5.086 2.208 0.0414302 coiled-coil domain containing 123 ZNF558 4.403 4.257 4.882 5.547 5.627 5.476 2.21 0.0156822 zinc finger protein 558 INTS9 5.821 4.984 5.177 6.714 6.321 6.169 2.21 0.0257373 integrator complex subunit 9 ZSCAN22 3.012 1.504 2.337 3.331 3.48 3.869 2.21 0.028421 zinc finger and SCAN domain containing 22 ERCC4 2.594 2.511 2.966 3.415 4.266 3.739 2.211 0.0198855 excision repair cross-complementing rodent repair deficiency, complementation group 4 ZBTB48 5.726 4.925 4.925 6.364 6.475 6.07 2.211 0.0212828 zinc finger and BTB domain containing 48 LRRC10 2.111 1.466 1.824 2.417 3.28 2.97 2.213 0.0262045 leucine rich repeat containing 10 GPS2 8.616 7.495 7.526 9.141 8.928 8.641 2.214 0.0495521 G protein pathway suppressor 2 PHAX 5.097 4.97 5.3 6.245 6.137 6.304 2.215 0.0058088 phosphorylated adaptor for RNA export CDK5R1 5.094 5.52 4.926 6.241 6.241 6.427 2.215 0.0102819 cyclin-dependent kinase 5, regulatory subunit 1 (p35) CUL4A 8.602 7.514 8.439 9.749 9.47 9.396 2.215 0.0127216 cullin 4A MAGOH 10.216 8.466 9.31 10.862 10.325 10.457 2.215 0.0450834 mago-nashi homolog, proliferation-associated (Drosophila) NIP7 8.825 7.166 8.059 9.607 8.957 9.207 2.216 0.0394076 nuclear import 7 homolog (S. cerevisiae) DEGS1 6.007 5.802 6.144 6.938 7.516 7.155 2.217 0.0074122 degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) SLC30A6 5.334 5.256 4.979 6.482 6.252 6.166 2.217 0.0077434 solute carrier family 30 (zinc transporter), member 6 UBE3B 3.812 4.022 4.443 5.172 4.961 5.261 2.217 0.0166967 ubiquitin protein ligase E3B ARMC6 7.162 4.877 6.297 8.127 7.217 7.446 2.217 0.0414231 armadillo repeat containing 6 PERS 4.322 4.468 4.441 5.345 5.59 5.648 2.218 0.0053567 period homolog 3 (Drosophila) SULT1A1 4.138 4.368 4.039 5.458 5.287 5.256 2.219 0.0051613 sulfotransferase family, cytosolic, 1A, phenol- preferring, member 1 ZCCHC4 5.422 5.358 5.575 6.58 6.725 6.273 2.219 0.0094198 zinc finger, CCHC domain containing 4 THG1L 2.939 2.744 2.75 4.262 3.901 3.579 2.22 0.0129033 tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) TSEN2 3.526 2.897 2.324 4.421 3.932 4.049 2.223 0.0226064 tRNA splicing endonuclease 2 homolog (S. cerevisiae) WDHD1 2.352 1.572 1.075 3.006 2.402 2.725 2.223 0.0489769 WD repeat and HMG-box DNA binding protein 1 PAQR7 7.553 6.937 7.442 8.599 8.669 8.297 2.23 0.0092151 progestin and adipoQ receptor family member VII RFPL3S 3.862 4.103 4.056 5.213 5.494 4.5 2.23 0.0275567 RFPL3 antisense RNA (non-protein coding) GPR153 2.927 2.365 3.262 4.36 3.838 4.087 2.234 0.0138306 G protein-coupled receptor 153 RHOD 4.01 4.689 3.998 5.839 5.396 5.16 2.236 0.0144652 ras homolog gene family, member D DUSP10 4.565 6.581 5.948 7.103 7.394 7.111 2.24 0.0256758 dual specificity phosphatase 10 OTX2OS1 3.03 3.812 3.409 3.999 4.975 4.738 2.24 0.0275982 No description C17orf73 5.24 4.149 4.884 5.981 6.342 6.048 2.241 0.0111641 chromosome 17 open reading frame 73 KLHL31 0.986 0.666 1.029 1.875 1.83 2.363 2.241 0.0114238 kelch-like 31 (Drosophila) LOC1001288 4.661 4.951 4.434 6.403 5.456 5.826 2.242 0.0164513 No description 42 DHX32 6.735 6.014 5.728 7.904 6.869 7.723 2.248 0.0203356 DEAN (Asp-Glu-Ala-His) box polypeptide 32 PNPT1 6.721 6.737 6.953 8.2 7.49 7.907 2.249 0.0166109 polyribonucleotide nucleotidyltransferase 1 LOC441208 0.708 1.88 2.557 2.85 3.728 2.54 2.252 0.0497775 No description ZNF768 7.192 5.171 6.205 7.301 7.736 7.377 2.253 0.0475817 zinc finger protein 768 PIGR 3.915 4.2 4.351 4.633 6.054 5.373 2.255 0.0313579 polymeric immunoglobulin receptor TMEM68 5.29 5.512 4.803 6.65 6.415 6.463 2.256 0.0063354 transmembrane protein 68 C16orf52 8.615 7.21 7.832 8.77 9.017 9.006 2.256 0.0496609 chromosome 16 open reading frame 52 HIPK3 4.61 3.46 4.553 5.786 5.245 5.325 2.258 0.0243736 homeodomain interacting protein kinase 3 TRAPPC6A 3.315 2.311 2.592 4.567 3.496 3.486 2.258 0.0494727 trafficking protein particle complex 6A ZNF133 2.429 2.978 3.278 3.869 4.028 4.455 2.261 0.0151506 zinc finger protein 133 GCKR 4.779 3.202 3.73 4.781 5.597 4.907 2.261 0.0482836 glucokinase (hexokinase 4) regulator MMP3 9.732 6.452 9.93 11.107 10.264 10.683 2.262 0.0456507 matrix metallopeptidase 3 (stromelysin 1, progelatinase) EID2 4.148 3.749 4.263 5.442 4.95 5.236 2.263 0.0106368 EP300 interacting inhibitor of differentiation 2 CSTF1 5.364 4.677 4.73 6.22 6.172 5.857 2.265 0.013583 cleavage stimulation factor, 3′ pre-RNA, subunit 1, 50kDa DGCR11 2.999 2.157 2.25 3.719 3.43 3.392 2.266 0.0266044 DiGeorge syndrome critical region gene 11 RRP15 6.051 5.372 5.429 6.861 6.65 6.553 2.267 0.0178558 ribosomal RNA processing 15 homolog (S. cerevisiae) PRRT3 3.246 4.227 3.658 4.86 4.84 4.595 2.268 0.0271761 proline-rich transmembrane protein 3 LOC1001909 2.021 1.388 1.715 3.204 3.14 2.556 2.271 0.0110002 No description 40 MBP 6.014 6.771 5.69 7.955 6.8 7.358 2.271 0.0345883 myelin basic protein COL22A1 1.065 1.44 1.513 2.254 2.648 2.663 2.279 0.0084446 collagen, type XXII, alpha 1 CARD10 7.241 7.632 7.717 8.957 8.429 8.587 2.279 0.012087 caspase recruitment domain family, member 10 SLC41A3 5.871 5.434 5.261 6.749 6.45 6.676 2.279 0.0124097 solute carrier family 41, member 3 NUP93 8.14 7.317 7.943 9.405 8.506 8.695 2.281 0.0373607 nucleoporin 93kDa FOXA1 2.602 3.195 2.482 4.582 3.318 3.793 2.283 0.0384074 forkhead box A1 FLJ16779 1.065 1.03 0.994 2.41 1.738 2.222 2.285 0.0128633 No description PDCD11 6.734 6.022 5.731 7.722 7.214 7.041 2.285 0.0253717 programmed cell death 11 FAM48A 5.071 5.014 5.357 6.264 6.376 6.257 2.286 0.0050132 family with sequence similarity 48, member A ATP2A1 2.827 3.259 2.948 4.14 4.587 3.577 2.286 0.0267311 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 WDR5 5.668 5.336 5.203 6.937 6.294 6.53 2.287 0.0111011 WD repeat domain 5 WDR46 7.78 6.648 6.869 8.426 7.841 8.111 2.287 0.0467926 WD repeat domain 46 GALNS 5.699 4.71 5.395 6.876 6.589 6.285 2.288 0.0133047 galactosamine (N-acetyl)-6-sulfate sulfatase LOC84740 1.936 1.067 0.929 2.724 2.488 2.124 2.289 0.0280854 No description S100A2 11.222 10.556 8.256 12.232 11.522 11.751 2.289 0.0343679 S100 calcium binding protein A2 MRPL4 7.891 7.264 7.389 8.82 8.586 8.493 2.292 0.0127388 mitochondrial ribosomal protein L4 C2orf14 4.669 4.802 4.459 5.656 6.3 5.84 2.293 0.006525 chromosome 2 open reading frame 14 MYLK3 4.886 4.265 4.261 5.458 5.538 5.515 2.293 0.0175152 myosin light chain kinase 3 PLEKHA6 5.923 5.367 4.825 6.464 6.605 6.564 2.293 0.019668 pleckstrin homology domain containing, family A member 6 C16orf93 2.886 2.993 3.757 4.892 4.121 4.19 2.293 0.0238563 chromosome 16 open reading frame 93 PHF5A 7.218 6.414 6.482 7.959 7.623 7.68 2.293 0.0248508 PHD finger protein 5A ABCC13 2.891 2.726 2.927 4.089 4.281 3.764 2.295 0.0063054 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene SLC6A15 1.876 1.958 1.737 4.026 2.807 3.076 2.298 0.0104779 solute carrier family 6 (neutral amino acid transporter), member 15 ACER3 7.367 6.473 6.347 8.107 7.607 7.675 2.3 0.0353774 alkaline ceramidase 3 CYP8B1 2.359 2.868 1.747 3.814 3.984 2.949 2.301 0.0289633 cytochrome P450, family 8, subfamily B, polypeptide 1 C8orf41 3.703 2.888 2.628 4.662 4.091 3.871 2.302 0.0340338 chromosome 8 open reading frame 41 SMARCA4 8.464 7.874 8.528 9.732 9.109 9.244 2.303 0.0229763 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 LOC1001300 0.708 0.283 0.88 1.911 1.773 2.084 2.305 0.0055448 No description 15 SLC12A4 5.444 4.955 5.238 6.649 6.357 6.277 2.305 0.0067375 solute carrier family 12 (potassium/chloride transporters), member 4 CD209 2.061 1.314 2.2 3.228 3.288 3.269 2.309 0.0065322 CD209 molecule RNASEH1 4.353 4.798 4.302 5.975 5.736 5.509 2.309 0.0069514 ribonuclease H1 BAG4 4.471 3.927 2.898 5.134 5.303 5 2.309 0.0206954 BCL2-associated athanogene 4 PXN 6.856 7.485 7.828 9.036 7.996 9.017 2.311 0.0245274 paxillin ZNF536 1.297 3.014 2.727 3.937 3.3 4.062 2.313 0.0299084 zinc finger protein 536 CWF19L1 3.171 2.478 2.295 4.403 3.474 3.69 2.317 0.0247178 CWF19-like 1, cell cycle control (S. pombe) BMS1P4 1.172 0.834 1.681 2.895 1.604 2.841 2.318 0.0380318 BMS1 pseudogene 4 ZMAT5 5.002 4.229 3.953 5.444 5.972 5.42 2.321 0.0209559 zinc finger, matrin-type 5 RPS6KB2 4.207 3.988 4.507 5.562 5.723 5.061 2.322 0.0109931 ribosomal protein S6 kinase, 70kDa, polypeptide 2 TTF1 5.201 4.815 3.762 6.417 5.525 5.909 2.322 0.0259977 transcription termination factor, RNA polymerase I LOC25845 5.6 4.712 4.826 6.295 6.041 5.96 2.322 0.0273163 No description RUNDC1 7.004 6.623 7.224 8.091 8.44 7.932 2.323 0.010103 RUN domain containing 1 PAR5 3.075 3.944 3.259 4.966 4.475 4.346 2.324 0.020357 No description CAPNS2 3.743 3.001 1.793 3.933 4.218 4.232 2.324 0.0442026 calpain, small subunit 2 TMEM170B 3.706 4.223 4.234 4.869 5.611 5.44 2.325 0.0118423 transmembrane protein 1706 PMCHL2 2.758 2.004 2.624 3.227 3.66 3.976 2.326 0.0203713 pro-melanin-concentrating hormone-like 2, pseudogene KRT86 6.004 6.548 5.324 7.528 6.713 7.221 2.326 0.0311497 keratin 86 WDR62 3.218 3.211 3.528 4.466 4.747 4.138 2.327 0.0113408 WD repeat domain 62 KCTD15 7.158 5.96 6.966 8.37 7.925 8.185 2.328 0.0108614 potassium channel tetramerisation domain containing 15 NIF3L1 2.936 2.868 2.229 4.155 3.513 3.764 2.328 0.0195629 NIF3 NGG1 interacting factor 3-like 1 (S. pombe) BCL2L13 7.496 6.151 7.389 8.117 8.715 8.161 2.328 0.0256829 BCL2-like 13 (apoptosis facilitator) ACD 4.292 3.17 2.967 4.814 4.895 4.185 2.328 0.0430572 adrenocortical dysplasia homolog (mouse) GGT6 3.106 3.528 3.69 4.558 4.91 4.74 2.329 0.0057409 gamma-glutamyltransferase 6 C16orf46 4.221 3.617 4.776 5.24 5.582 5.441 2.329 0.0196823 chromosome 16 open reading frame 46 INTS7 8.944 8.408 8.474 9.629 10.285 9.643 2.33 0.011539 integrator complex subunit 7 MITD1 2.14 1.907 2.497 3.313 3.49 3.361 2.331 0.0068284 MIT, microtubule interacting and transport, domain containing 1 SLC15A2 3.222 3.093 3.918 5.026 4.314 4.663 2.331 0.0154461 solute carrier family 15 (H+/peptide transporter), member 2 WDR20 6.103 4.719 5.366 6.577 6.587 6.646 2.331 0.0265114 WD repeat domain 20 FLJ45445 8.371 8.583 8.925 10.148 9.643 9.653 2.335 0.0108206 No description WDR89 4.293 2.807 3.516 4.656 4.739 4.909 2.335 0.0289561 WD repeat domain 89 NDUFAB1 7.914 7.11 6.692 8.482 7.916 8.53 2.336 0.0445868 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa CCNA2 2.993 1.66 2.339 3.746 3.564 3.117 2.338 0.0373678 cyclin A2 WDR90 3.129 2.735 3.059 4.751 3.958 4.285 2.339 0.0069235 WD repeat domain 90 SCT 1.571 2.004 0.842 2.189 2.797 2.889 2.339 0.0324104 secretin GCN1L1 7.563 7.124 7.401 8.789 8.394 8.618 2.34 0.0056786 GCN1 general control of amino-acid synthesis 1- like 1 (yeast) YPEL1 5.357 4.933 5.535 6.761 6.464 6.417 2.34 0.0065751 yippee-like 1 (Drosophila) RNF157 3.297 3.365 2.532 4.551 4.525 4.232 2.341 0.0078965 ring finger protein 157 PFDN6 7.175 5.247 6.242 7.85 7.358 7.469 2.341 0.0373163 prefoldin subunit 6 NCOA6 6.056 4.902 5.633 7.035 6.862 6.626 2.344 0.0149689 nuclear receptor coactivator 6 PPIL6 4.859 4.07 3.955 5.184 5.455 5.313 2.344 0.0304851 peptidylprolyl isomerase (cyclophilin)-like 6 DUSP7 10.617 9.421 9.942 11.324 10.862 11.171 2.345 0.0306182 dual specificity phosphatase 7 HIPK2 8.821 8.118 8.408 10.156 9.155 9.638 2.346 0.0213737 homeodomain interacting protein kinase 2 LOC285456 2.651 2.812 2.358 3.963 4.042 2.933 2.346 0.0441311 No description RC3H2 5.185 4.105 4.67 6.09 5.817 5.901 2.347 0.0135616 ring finger and CCCH-type domains 2 WNT6 3.423 4.068 4.03 4.654 5.487 5.164 2.347 0.0144151 wingless-type MMTV integration site family, member 6 ZNF232 5.316 4.817 5.147 6.547 5.738 6.386 2.347 0.0191751 zinc finger protein 232 SNORA78 5.526 5.4 5.72 5.929 6.983 6.756 2.347 0.0394448 small nucleolar RNA, H/ACA box 78 XKRX 1.037 2.533 2.014 3.643 2.548 3.246 2.348 0.0383652 XK, Kell blood group complex subunit-related, X- linked SIRPB2 2.6 2.677 1.062 2.798 3.909 3.562 2.348 0.0472777 signal-regulatory protein beta 2 P2RX7 4.112 3.778 4.203 4.604 5.435 5.358 2.349 0.0222931 purinergic receptor P2X, ligand-gated ion channel, 7 ARHGAP22 2.97 2.795 2.6 4.229 3.655 4.028 2.351 0.008803 Rho GTPase activating protein 22 TOP1 7.946 6.727 7.301 8.391 8.851 8.536 2.353 0.0191279 topoisomerase (DNA) I ELP2P 2.669 1.075 1.762 3.632 2.601 2.996 2.353 0.045215 No description SLC7A5P2 6.739 6.039 4.373 7.035 7.818 7.274 2.354 0.0282614 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 2 WHSC1 6.655 6.355 6.486 7.879 7.695 7.723 2.357 0.0030443 Wolf-Hirschhorn syndrome candidate 1 MUC1 5.183 3.648 4.424 5.422 6.146 5.661 2.357 0.0274286 mucin 1, cell surface associated SFRS14 6.582 5.807 6.73 7.522 7.967 7.608 2.358 0.0111855 No description RPS12 12.823 11.989 12.05 13.704 13.287 13.263 2.358 0.0209687 ribosomal protein S12 CSNK2A2 7.261 6.675 6.528 7.913 8.016 7.823 2.359 0.0156493 casein kinase 2, alpha prime polypeptide QPCTL 2.609 3.112 2.336 4.402 3.762 3.574 2.359 0.0180239 glutaminyl-peptide cyclotransferase-like C16orf55 1.651 1.241 1.589 2.827 2.91 2.06 2.359 0.0224569 chromosome 16 open reading frame 55 NAF1 7.012 6.435 7.298 8.163 8.528 8.251 2.36 0.0066874 nuclear assembly factor 1 homolog (S. cerevisiae) PPTC7 5.601 5.716 6.221 6.812 7.46 7.34 2.36 0.0076876 PTC7 protein phosphatase homolog (S. cerevisiae) DCLRE1A 2.248 2.722 1.72 3.487 3.114 3.721 2.36 0.0190356 DNA cross-link repair 1A ESRP2 6.27 5.608 6.485 7.649 6.846 7.513 2.36 0.0212277 epithelial splicing regulatory protein 2 C9orf102 1.748 2.028 2.18 3.269 3.233 3.333 2.363 0.003412 chromosome 9 open reading frame 102 OGFRL1 6.813 6.762 7.73 8.003 8.964 8.309 2.364 0.0200057 opioid growth factor receptor-like 1 FGF5 3.653 3.601 3.514 4.985 4.366 4.843 2.365 0.0098061 fibroblast growth factor 5 CLTB 11.248 9.465 10.177 11.739 11.419 11.346 2.365 0.047058 clathrin, light chain B C4orf10 5.447 5.023 5.158 6.54 6.265 6.441 2.366 0.0053853 chromosome 4 open reading frame 10 KLK14 2.382 2.931 2.671 4.048 3.96 3.624 2.366 0.0079953 kallikrein-related peptidase 14 ZNF709 3.308 2.691 2.688 3.93 4.252 4.14 2.366 0.0095142 zinc finger protein 709 AMN 2.956 2.004 2.724 4.728 3.247 3.672 2.367 0.0318294 amnionless homolog (mouse) NR5A1 0.817 1.629 0.757 2.946 1.678 2.06 2.368 0.0423811 nuclear receptor subfamily 5, group A, member 1 CCDC144A 4.378 3.837 4.11 5.573 5.354 5.216 2.369 0.0056142 coiled-coil domain containing 144A SECISBP2 5.753 4.648 4.915 6.179 6.16 5.924 2.37 0.0455827 SECIS binding protein 2 SMURF1 8.016 6.622 7.808 9.186 9.053 8.267 2.371 0.0283487 SMAD specific E3 ubiquitin protein ligase 1 SFRS15 7.65 6.159 7.216 8.294 8.882 8.462 2.372 0.0134843 No description TNFRSF9 2.976 3.635 2.284 3.855 4.223 4.314 2.373 0.0325778 tumor necrosis factor receptor superfamily, member 9 LMTK3 4.894 3.808 3.753 5.118 6.07 5.001 2.376 0.0369171 lemur tyrosine kinase 3 C19orf28 8.353 8.026 7.678 9.603 8.937 9.025 2.377 0.0164585 chromosome 19 open reading frame 28 EIF5B 9.476 8.984 9.054 10.562 10.233 10.33 2.378 0.0070323 eukaryotic translation initiation factor 5B LOC220729 4.918 3.945 5.588 6.168 6.833 6.101 2.378 0.0167332 No description LOC1001305 7.628 6.543 6.556 7.793 7.947 8.137 2.378 0.0408163 No description 81 C12orf48 0.825 1.15 2.282 2.97 2.317 2.4 2.378 0.0480761 chromosome 12 open reading frame 48 ZBTB3 1.767 1.494 1.52 3.125 2.372 2.771 2.379 0.0120541 zinc finger and BTB domain containing 3 FANCA 4.017 4.035 4.27 4.817 5.521 5.433 2.38 0.012957 Fanconi anemia, complementation group A BCL7A 5.69 6.298 6.07 7.617 6.615 7.322 2.382 0.0231552 B-cell CLL/lymphoma 7A SLC2A10 4.783 3.578 4.463 6.036 4.959 5.64 2.383 0.0307412 solute carrier family 2 (facilitated glucose transporter), member 10 LOC1002722 1.077 1.464 1.611 2.843 2.488 2.717 2.384 0.00522 No description 17 ZNF611 4.827 4.5 5.072 6.063 6.389 5.753 2.385 0.0088231 zinc finger protein 611 ZNF260 2.8 2.756 3.015 3.559 4.055 4.343 2.386 0.0148122 zinc finger protein 260 LOC1001348 2.628 2.707 2.779 3.962 4.435 3.799 2.387 0.0043836 No description 68 SLC25A10 3.508 2.588 2.526 4.622 4.764 3.181 2.388 0.0430715 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 ALG13 3.001 2.677 1.747 4.258 3.774 3.879 2.389 0.0104851 asparagine-linked glycosylation 13 homolog (S. cerevisiae) EP400 7.305 6.566 7.274 8.562 8.276 8.212 2.39 0.0087365 E1A binding protein p400 REXO1 8.168 7.12 7.131 8.377 8.872 8.646 2.39 0.0277935 REX1, RNA exonuclease 1 homolog (S. cerevisiae) BAG2 3.622 3.258 2.885 4.646 4.516 4.146 2.392 0.0135015 BCL2-associated athanogene 2 SEMA3B 7.431 7.024 6.951 8.283 8.736 8.158 2.393 0.0082042 sema domain, immunoglobulin domain (ig), short basic domain, secreted, (semaphorin) 3B MRPS36 7.91 7.21 7.272 8.531 8.543 8.499 2.393 0.0171718 mitochondrial ribosomal protein S36 MGC3771 2.266 1.99 1.611 2.967 3.249 3.342 2.394 0.0084868 No description EFTUD1 6.101 5.972 6.045 7.73 6.619 7.304 2.394 0.0198784 elongation factor Tu GTP binding domain containing 1 CCDC110 1.408 1.471 0.251 1.949 2.731 2.6 2.396 0.0201452 coiled-coil domain containing 110 EBNA1BP2 7.093 7.477 7.07 8.738 7.844 8.484 2.397 0.0193339 EBNA1 binding protein 2 C17orf55 4.014 3.41 4.184 4.212 5.615 5.275 2.397 0.0442835 chromosome 17 open reading frame 55 NKRF 6.268 5.524 5.724 6.832 7.235 6.988 2.402 0.0126844 NFKB repressing factor SYNGR3 1.888 −0.046 1.538 2.803 2.999 2.735 2.403 0.0143307 synaptogyrin 3 C1orf135 9.672 8.847 9.089 10.599 10.496 10.112 2.403 0.0147521 chromosome 1 open reading frame 135 FAM86B2 4.123 3.704 4.368 5.377 4.969 5.788 2.404 0.0108786 family with sequence similarity 86, member B2 NKAP 5.226 4.993 4.958 6.452 6.367 6.224 2.405 0.0028053 NFKB activating protein ABCB5 1.875 1.44 1.762 3.316 2.835 2.708 2.408 0.0078844 ATP-binding cassette, sub-family B (MDR/TAP), member 5 ARFGAP1 4.329 4.699 3.964 5.672 5.47 5.597 2.408 0.0079037 ADP-ribosylation factor GTPase activating protein 1 PRMT1 10.708 10.007 10.649 12.15 11.275 11.416 2.408 0.0244881 protein arginine methyltransferase 1 ZRSR2 4.568 4.634 3.843 5.755 5.788 5.905 2.413 0.0046713 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 LMTK2 7.25 7.894 7.608 9.006 8.646 8.88 2.415 0.0071861 lemur tyrosine kinase 2 CAPN2 7.525 8.619 7.533 8.798 9.02 8.968 2.416 0.042165 calpain 2, (m/ll) large subunit C5orf35 4.056 3.787 4.464 5.245 5.331 5.693 2.42 0.006867 chromosome 5 open reading frame 35 ZNF70 2.791 2.623 2.712 3.616 4.068 3.991 2.424 0.0058654 zinc finger protein 70 PILRA 2.982 4.098 3.311 4.588 4.499 5.079 2.424 0.0196952 paired immunoglobin-like type 2 receptor alpha EIF4G2 10.177 10.936 11.007 11.804 12.15 12.285 2.425 0.0086413 eukaryotic translation initiation factor 4 gamma, 2 KIAA0895 4.005 3.399 3.009 4.955 4.674 4.677 2.425 0.0114381 KIAA0895 DHX30 8.723 7.521 7.499 9.511 8.777 8.922 2.425 0.0418573 DEAH (Asp-Glu-Ala-His) box polypeptide 30 GLDC 0.478 0.588 0.543 1.757 3.046 1.77 2.428 0.0074265 glycine dehydrogenase (decarboxylating) WDR31 1.19 0.819 1.47 2.4 2.751 2.115 2.429 0.0100429 WD repeat domain 31 MARS 9.352 9.31 8.813 11.017 10.127 10.094 2.43 0.0172233 methionyl-tRNA synthetase NDUFB10 4.101 4.536 3.38 4.661 5.387 5.786 2.43 0.0296423 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa TRIP4 3.5 2.361 2.648 4.432 4.424 3.644 2.432 0.0202755 thyroid hormone receptor interactor 4 BOK 6.57 6.334 5.459 7.853 7.289 7.375 2.433 0.0133247 BCL2-related ovarian killer FBXO2 7.603 7.224 6.945 8.536 8.508 8.288 2.435 0.0091128 F-box protein 2 C9orf91 5.367 5.299 5.211 6.652 6.528 6.53 2.436 0.001853 chromosome 9 open reading frame 91 GTF2H2 4.898 3.818 4.34 5.109 6.182 5.139 2.436 0.0478908 general transcription factor IIH, polypeptide 2, 44kDa SLC4A2 7.906 6.651 6.806 8.44 8.463 7.937 2.439 0.0359898 solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) RPL14 11.414 10.612 10.941 11.989 12.341 12.232 2.446 0.0119489 ribosomal protein L14 RPL32P3 4.128 3.378 3.085 4.852 4.684 4.376 2.447 0.028021 ribosomal protein L32 pseudogene 3 ZNF594 2.418 1.314 2.211 3.713 3.321 3.031 2.453 0.0146441 zinc finger protein 594 TMEM53 5.806 4.826 5.172 6.466 6.746 6.192 2.453 0.018695 transmembrane protein 53 C1orf83 6.994 6.342 6.653 7.798 8.158 7.948 2.454 0.0061072 chromosome 1 open reading frame 83 WDR81 5.044 4.436 5.193 6.41 6.34 5.846 2.456 0.0102397 WD repeat domain 81 ZNF566 3.931 3.273 4.018 5.228 5.27 4.816 2.457 0.0075367 zinc finger protein 566 LOC1001314 6.765 5.852 6.176 7.673 7.395 7.472 2.457 0.0116999 No description 96 ODF2 6.848 5.687 6.049 8.05 6.985 7.59 2.458 0.0222208 outer dense fiber of sperm tails 2 HSPB8 9.41 9.475 7.962 10.259 10.773 10.641 2.459 0.0133806 heat shock 22kDa protein 8 DNAJC11 6.207 5.632 5.742 8.023 6.522 7.041 2.46 0.0244473 DnaJ (Hsp40) homolog, subfamily C, member 11 PLOD3 7.898 6.792 6.822 8.224 8.286 8.091 2.46 0.0431037 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 SCAP 7.254 6.446 6.858 8.18 8.115 8.158 2.462 0.0071618 SREBF chaperone OSR1 7.137 6.381 6.947 7.799 8.366 8.247 2.462 0.0095428 odd-skipped related 1 (Drosophila) ADAT1 1.77 2.737 2.406 3.057 3.706 4.216 2.462 0.0196144 adenosine deaminase, tRNA-specific 1 SMOC1 3.662 5 3.75 5.513 5.737 4.962 2.462 0.0325921 SPARC related modular calcium binding 1 FXR2 7.616 6.899 7.189 8.916 8.385 8.335 2.463 0.0093275 fragile X mental retardation, autosomal homolog 2 ANKRD42 3.534 1.611 3.273 4.688 4.444 4.573 2.463 0.013143 ankyrin repeat domain 42 HSPBP1 7.389 6.301 6.403 8.369 7.842 7.602 2.464 0.0252694 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 MRPL28 7.447 5.513 6.15 8.203 7.448 7.452 2.465 0.0450905 mitochondrial ribosomal protein L28 FAM179A 0.162 1.067 2.168 2.882 2.053 2.37 2.467 0.0497181 family with sequence similarity 179, member A CSPG5 2.828 2.621 2.652 4.335 3.843 3.956 2.469 0.0037025 chondroitin sulfate proteoglycan 5 (neuroglycan C) JAG1 8.075 8.903 8.292 9.6 9.596 9.59 2.469 0.0128196 jagged 1 DHDDS 4.339 3.539 2.925 5.526 4.233 5.276 2.476 0.0293575 dehydrodolichyl diphosphate synthase GPLD1 3.235 3.31 3.72 5.029 4.403 4.722 2.478 0.0072612 glycosylphosphatidylinositol specific phospholipase D1 EPRS 4.172 4.017 3.192 5.851 4.501 4.921 2.479 0.0312013 glutamyl-prolyl-tRNA synthetase GBP6 2.056 2.724 2.902 3.852 4.212 3.775 2.48 0.0076948 guanylate binding protein family, member 6 YARS 9.105 8.401 8.7 10.343 9.712 10.068 2.481 0.0092008 tyrosyl-tRNA synthetase PBLD 1.645 2.787 1.936 3.248 3.445 3.181 2.482 0.0235737 phenazine biosynthesis-like protein domain containing ACCN1 4.222 4.302 2.83 5.614 5.225 5.055 2.484 0.0165894 amiloride-sensitive cation channel 1, neuronal GAL3ST4 1.065 1.269 1.859 2.841 2.787 2.379 2.487 0.0107555 galactose-3-O-sulfotransferase 4 KRBA1 5.49 5.892 6.445 7.759 6.99 7.052 2.487 0.0154139 KRAB-A domain containing 1 CSNK1E 11.746 10.735 9.844 12.05 12.101 12.041 2.487 0.038881 casein kinase 1, epsilon MGC12916 2.419 3.064 3.757 4.213 4.379 4.391 2.489 0.0218602 No description PLXNB3 2.33 3.503 2.661 3.646 4.424 4.49 2.49 0.0197467 plexin B3 FZD3 6.241 5.937 4.275 7.446 7.253 7.158 2.491 0.0122508 frizzled homolog 3 (Drosophila) POP1 5.189 4.13 4.375 6.094 5.448 5.889 2.492 0.020093 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) OVOL2 4.911 4.855 4.561 5.88 6.273 6.018 2.495 0.0043979 ovo-like 2 (Drosophila) HOOK2 5.854 6.528 6.465 7.847 7.647 7.639 2.496 0.0043056 hook homolog 2 (Drosophila) MLL4 8.59 7.33 7.892 9.3 9.192 9.215 2.502 0.0163061 No description SLC5A1 2.532 2.022 2.244 3.413 4.376 3.346 2.503 0.0098591 solute carrier family 5 (sodium/glucose cotransporter), member 1 C2orf42 3.51 3.222 1.607 4.105 4.833 4.164 2.503 0.0231337 chromosome 2 open reading frame 42 C1orf51 6.472 6.375 6.283 7.474 8.009 7.699 2.504 0.0036596 chromosome 1 open reading frame 51 ZG16B 1.714 1.998 0.422 3.038 2.751 3.128 2.504 0.0125971 zymogen granule protein 16 homolog B (rat) TLE1 7.877 7.031 8.468 9.202 9.685 9.164 2.505 0.0110074 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) MORC2 7.826 6.373 7.051 8.182 8.53 8.376 2.505 0.0239594 MORC family CW-type zinc finger 2 KAT5 6.718 6.079 5.979 7.603 7.494 7.304 2.507 0.0111297 K(lysine) acetyltransferase 5 PTRH1 5.658 4.095 5.021 6.893 6.333 6.347 2.507 0.0118938 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) CASP8 5.276 5.095 4.503 6.376 6.603 5.9 2.508 0.0105302 caspase 8, apoptosis-related cysteine peptidase ZNF565 1.48 0.862 1.894 2.189 2.885 3.013 2.509 0.0197539 zinc finger protein 565 PTRH2 3.851 3.548 2.471 4.453 4.59 5.18 2.512 0.0172111 peptidyl-tRNA hydrolase 2 SUMO1 2.417 1.287 1.219 2.87 2.548 3.149 2.512 0.0290663 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) KHDRBS3 9.445 8.038 8.59 9.606 9.919 10.015 2.512 0.0358467 KH domain containing, RNA binding, signal transduction associated 3 RCE1 6.843 5.693 6.052 7.346 7.618 7.381 2.513 0.017551 RCE1 homolog, prenyl protein peptidase (S. cerevisiae) ZNF394 3.66 2.946 3.077 4.37 4.623 4.413 2.525 0.008924 zinc finger protein 394 PDCD7 7.816 7.425 7.368 8.553 9.154 8.882 2.528 0.0060042 programmed cell death 7 CBX8 5.109 5.15 5.727 7.065 6.611 6.134 2.528 0.014976 chromobox homolog 8 NCOR2 7.415 6.374 5.783 8.258 8.278 7.122 2.53 0.0395972 nuclear receptor corepressor 2 ZDHHC13 5.7 4.915 5.137 6.85 6.308 6.478 2.533 0.0101438 zinc finger, DHHC-type containing 13 DAZAP1 9.555 8.277 9.141 10.734 10.483 10.371 2.534 0.0085798 DAZ associated protein 1 OST4 8.878 8.219 8.344 9.753 9.676 9.686 2.535 0.0076433 oligosaccharyltransferase 4 homolog (S. cerevisiae) TRMT1 8.643 8.178 8.021 9.747 9.367 9.682 2.542 0.0060643 TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae) MURC 3.289 2.782 3.071 4.322 4.7 4.13 2.546 0.0057208 muscle-related coiled-coil protein TRIM56 4.637 4.001 4.081 5.557 5.539 5.349 2.547 0.0075224 tripartite motif-containing 56 ZNF347 2.966 1.305 1.928 4.134 3.277 3.139 2.547 0.0268842 zinc finger protein 347 FAM83E 5.147 4.075 4.535 5.885 6.148 5.526 2.549 0.0174279 family with sequence similarity 83, member E SNORD23 2.908 1.783 2.758 4.203 3.874 4.109 2.551 0.0064985 small nucleolar RNA, C/D box 23 TNFRSF12A 10.483 10.047 9.631 11.962 10.913 11.398 2.552 0.0146176 tumor necrosis factor receptor superfamily, member 12A TMC5 5.798 4.92 5.738 6.981 7.151 6.987 2.554 0.0043908 transmembrane channel-like 5 MTHFD2L 3.481 4.237 3.543 5.651 4.749 4.897 2.557 0.0142212 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like NCBP2 8.413 6.943 7.746 9.135 8.945 9.101 2.558 0.0184575 nuclear cap binding protein subunit 2, 20kDa CEACAM19 6.781 5.733 5.382 8.086 7.088 6.883 2.558 0.0303284 carcinoembryonic antigen-related cell adhesion molecule 19 LOC152225 6.866 6.252 6.346 7.61 7.885 7.711 2.563 0.0071933 No description RBM19 6.562 5.687 6.486 7.92 7.094 7.401 2.563 0.0211283 RNA binding motif protein 19 CDK7 3.98 5.392 3.901 6.169 5.26 5.869 2.564 0.033681 cyclin-dependent kinase 7 BMS1P1 3.514 3.323 3.089 4.501 4.873 4.455 2.566 0.0047972 BMS1 pseudogene 1 IL12RB1 3.368 3.427 2.775 4.863 4.087 4.729 2.568 0.0096501 interleukin 12 receptor, beta 1 EIF4ENIF1 6.277 5.176 5.519 6.879 7.05 6.692 2.568 0.0189204 eukaryotic translation initiation factor 4E nuclear import factor 1 PHC2 9.771 8.986 9.063 11.021 10.35 10.538 2.573 0.0099993 polyhomeotic homolog 2 (Drosophila) C17orf96 10.804 8.687 9.754 10.864 11.324 11.118 2.574 0.0426994 chromosome 17 open reading frame 96 VPS72 5.364 4.332 4.179 5.905 5.728 5.544 2.575 0.0361122 vacuolar protein sorting 72 homolog (S. cerevisiae) GRK6 5.767 6.036 5.441 7.614 6.925 6.807 2.576 0.0090134 G protein-coupled receptor kinase 6 HOXC13 0.838 1.758 0.871 2.718 2.36 2.204 2.577 0.0153753 homeobox C13 MGAT1 10.283 8.869 9.05 10.415 10.319 10.813 2.577 0.0490534 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N- acetylglucosaminyltransferase CDHR1 1.182 1.864 1.075 2.715 2.442 2.854 2.578 0.0096008 cadherin-related family member 1 MOBKL1B 6.91 5.316 6.272 7.373 8.277 7.639 2.579 0.0150805 MOB1. Mps One Binder kinase activator-like 1B (yeast) C17orf89 7.562 6.396 6.707 8.739 7.899 8.074 2.579 0.0192559 chromosome 17 open reading frame 89 PTBP1 11.017 9.001 10.15 12.129 11.518 11.226 2.58 0.0250798 polypyrimidine tract binding protein 1 CDCP1 6.3 7.608 6.666 8.55 7.667 8.155 2.58 0.0295714 CUB domain containing protein 1 SLC23A3 2.352 2.319 2.922 3.687 3.847 4.085 2.581 0.0057945 solute carrier family 23 (nucleobase transporters), member 3 IL18 5.496 5.078 6.424 7.121 6.865 6.794 2.582 0.0230207 interleukin 18 (interferon-gamma-inducing factor) TMEM161B 3.93 3.118 3.886 5.256 4.8 5.269 2.584 0.0064914 transmembrane protein 161B LOC339047 3.675 4.166 4.398 5.557 5.516 5.537 2.586 0.0036882 No description THOP1 7.293 6.672 6.577 8.684 7.68 8.043 2.586 0.0170988 thimet oligopeptidase 1 TMED2 10.578 9.834 9.386 11.207 10.936 11.285 2.589 0.0216606 transmembrane emp24 domain trafficking protein 2 ABTB2 6.749 2.851 5.678 6.885 7.447 7.051 2.589 0.0432646 ankyrin repeat and BTB (POZ) domain containing 2 TMEM55B 3.726 3.315 3.306 4.288 5.256 4.69 2.594 0.0120262 transmembrane protein 55B VAC14 2.443 2.819 2.815 4.644 3.818 3.819 2.595 0.0078629 Vac14 homolog (S. cerevisiae) ARHGDIA 11.02 9.266 9.793 11.934 11.082 11.169 2.596 0.0352765 Rho GDP dissociation inhibitor (GDI) alpha PLCH2 4.742 5.722 5.039 6.467 6.516 6.119 2.598 0.0174208 phospholipase C, eta 2 MAPK8 3.672 3.247 3.329 5.521 3.987 4.706 2.598 0.0240602 mitogen-activated protein kinase 8 SBNO1 6.577 6.674 6.47 7.567 8.187 7.955 2.599 0.0046641 strawberry notch homolog 1 (Drosophila) SLC27A5 5.367 4.597 3.83 5.976 6.076 5.838 2.6 0.0198068 solute carrier family 27 (fatty acid transporter), member 5 CDK4 9.075 7.825 8.274 10.165 9.204 10.032 2.601 0.0193911 cyclin-dependent kinase 4 ROMO1 4.505 4.344 5.942 5.723 6.437 6.368 2.601 0.0456028 reactive oxygen species modulator 1 RPS15 7.447 7.42 6.731 8.236 8.826 8.541 2.602 0.0091808 ribosomal protein S15 HES7 4.961 6.091 6 6.855 7.472 6.913 2.604 0.0152343 hairy and enhancer of split 7 (Drosophila) FAM173A 5.026 4.459 4.856 6.238 6.405 5.954 2.607 0.0040867 family with sequence similarity 173, member A C3orf33 2.539 2.882 2.344 4.582 3.803 3.727 2.608 0.0072147 chromosome 3 open reading frame 33 SMARCE1 5.791 5.234 5.207 7.175 6.167 6.801 2.61 0.0147449 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 TMEM208 7.103 5.569 6.145 7.877 7.007 7.529 2.61 0.044946 transmembrane protein 208 TMEM180 3.834 3.245 3.109 5.183 5.144 4.493 2.611 0.0053352 transmembrane protein 180 S100A16 9.921 8.374 8.701 10.808 9.763 10.415 2.618 0.0358789 S100 calcium binding protein A16 LOC730668 3.111 2.97 2.996 4.455 4.386 4.375 2.62 0.0010732 No description DLL3 1.275 1.715 1.471 3.742 2.863 2.54 2.624 0.0075152 delta-like 3 (Drosophila) HSPA1L 2.541 0.588 0.96 1.757 3.933 3.502 2.624 0.0418366 heat shock 70kDa protein 1 -like LILRA5 3.73 3.559 2.521 5.123 4.6 4.232 2.625 0.0196537 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 PITPNM3 2.646 1.49 2.246 3.671 3.336 3.64 2.627 0.010151 PITPNM family member 3 STK32C 4.618 4.228 5.343 6.357 5.743 6.012 2.628 0.0162918 serine/threonine kinase 32C CCNB1 4.326 3.44 3.948 5.058 5.757 4.835 2.63 0.0165679 cyclin B1 MS4A7 5.849 5.274 4.616 6.742 6.669 6.245 2.63 0.017971 membrane-spanning 4-domains, subfamily A, member 7 PTPN6 3.792 3.42 3.768 4.927 5.635 4.817 2.634 0.005552 protein tyrosine phosphatase, non-receptor type 6 TXLNG 4.676 3.776 4.858 5.937 6.255 5.51 2.634 0.0112814 taxilin gamma MCCC2 4.814 4.249 4.214 6.091 6.001 5.614 2.637 0.004189 methylcrotonoyl-CoA carboxylase 2 (beta) TMEM147 7.228 6.265 5.859 8.282 7.664 7.57 2.637 0.019761 transmembrane protein 147 RPS6 14.08 12.935 13.834 15.235 15.038 15.235 2.641 0.0065608 ribosomal protein S6 FZD5 5.665 4.275 4.748 6.238 6.15 6.134 2.642 0.0216255 frizzled homolog 5 (Drosophila) CAPN10 1.362 2.474 1.075 3.163 2.763 2.575 2.642 0.0361608 calpain 10 AEBP1 6.061 5.48 5.558 6.883 7.388 7.214 2.645 0.004101 AE binding protein 1 NCRNA00114 2.986 2.682 2.638 4.089 3.998 4.391 2.648 0.0031158 non-protein coding RNA 114 TECPR2 8.714 7.859 8.389 8.631 10.368 9.794 2.648 0.0434178 tectonin beta-propeller repeat containing 2 KIAA1704 2.219 2.17 2.758 4.215 3.624 3.336 2.649 0.0107484 KIAA1704 CYP24A1 1.994 2.821 3.582 4.227 4.11 4.346 2.649 0.0175295 cytochrome P450, family 24, subfamily A, polypeptide 1 SNRNP25 6.534 5.087 5.96 7.352 7.94 7.193 2.65 0.0102111 small nuclear ribonucleoprotein 25kDa (U11 /U12) KRT7 12.594 12.05 12.125 14.221 12.979 13.531 2.65 0.0178736 keratin 7 BCL2L1 8.661 6.186 8.087 10.067 8.783 9.155 2.65 0.0363526 BCL2-like 1 C14orf104 7.407 6.124 6.094 7.501 7.811 7.579 2.651 0.0481799 chromosome 14 open reading frame 104 AEN 6.674 5.683 6.622 8.081 7.867 7.779 2.652 0.0053066 apoptosis enhancing nuclease CITED4 8.717 8.807 9.331 10.777 9.512 10.215 2.652 0.0272691 Cbp/p300-interacting transactivator, with Glu/Asp- rich carboxy-terminal domain, 4 CLCN2 6.867 5.309 6.253 6.956 8.274 7.351 2.652 0.0353009 chloride channel 2 PRR15 1.709 1.108 1.893 3.764 2.519 2.745 2.658 0.0159412 proline rich 15 FAM166A 6.888 6.739 6.515 8.067 8.151 8.171 2.66 0.0017958 family with sequence similarity 166, member A WDR66 3.116 2.431 2.997 4.279 4.493 4.408 2.66 0.0028339 WD repeat domain 66 ZNHIT1 3.7 2.828 1.818 4.38 3.817 4.24 2.66 0.0336202 zinc finger, HIT-type containing 1 DPY19L2P2 3.167 2.6 3.287 4.666 4.409 4.58 2.663 0.0031087 dpy-19-like 2 pseudogene 2 (C. elegans) C5orf38 4.84 4.5 4.284 6.122 5.991 5.697 2.663 0.0041747 chromosome 5 open reading frame 38 MRPL52 8.39 8.174 7.506 9.802 9.058 9.257 2.663 0.0121335 mitochondrial ribosomal protein L52 CLIP2 8.475 7.019 7.541 8.955 9.042 8.449 2.663 0.0449975 CAP-GLY domain containing linker protein 2 HLA-J 2.028 2.354 3.063 3.625 3.962 3.768 2.665 0.0122437 major histocompatibility complex, class I, J (pseudogene) SMCR7L 7.789 6.676 6.966 8.689 8.092 8.511 2.668 0.0180554 Smith-Magenis syndrome chromosome region, candidate 7-like PRRG4 4.653 4.682 3.602 5.743 6.098 6.03 2.669 0.0054983 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) SLC27A4 4.403 2.905 3.259 5.455 4.323 4.807 2.672 0.0345596 solute carrier family 27 (fatty acid transporter), member 4 CECR5 5.225 4.835 5.869 7.198 6.513 6.644 2.673 0.0091415 cat eye syndrome chromosome region, candidate 5 RRS1 6.983 5.881 5.915 7.765 7.3 7.74 2.674 0.0161508 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) MRFAP1L1 7.659 6.114 6.734 7.943 8.155 8.186 2.677 0.0287644 Morf4 family associated protein 1 -like 1 PYGO1 2.651 1.044 2.414 2.957 4.072 3.128 2.677 0.040855 pygopus homolog 1 (Drosophila) C17orf80 4.813 3.353 3.768 5.097 6.028 5.19 2.679 0.0210517 chromosome 17 open reading frame 80 C8orf86 6.703 6.277 6.073 8.081 7.703 7.495 2.68 0.0054912 chromosome 8 open reading frame 86 LDLRAD3 5.296 5.267 6.53 7.102 6.689 6.758 2.68 0.037664 low density lipoprotein receptor class A domain containing 3 SEPHS2 7.5 6.214 6.101 7.756 7.912 7.527 2.687 0.0459984 selenophosphate synthetase 2 MEP1B 1.077 1.685 0.585 2.504 2.261 3.022 2.689 0.0101753 meprin A, beta S100A11 10.783 9.619 10.052 11.973 11.479 11.362 2.689 0.0109537 S100 calcium binding protein A11 UBE3C 8.369 7.135 7.642 9.705 8.925 9.07 2.69 0.0113551 ubiquitin protein ligase ESC AHSA1 9.491 8.16 8.374 9.59 10.114 9.926 2.695 0.0324175 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) GNA15 2.717 2.761 1.793 4.193 3.793 4.006 2.697 0.0055184 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) CRYAB 10.972 11.11 11.719 12.426 12.598 12.542 2.698 0.0085333 crystallin, alpha B FAM153B 4.791 4.884 4.428 5.86 6.62 5.993 2.699 0.0053638 family with sequence similarity 153, member B CBX6 7.526 6.593 5.899 8.027 8.266 7.93 2.702 0.0205595 chromobox homolog 6 WNK2 4.916 5.495 6.013 6.349 7.597 6.471 2.702 0.0288431 WNK lysine deficient protein kinase 2 EIF4G1 8.521 7.937 7.802 9.877 9.237 9.475 2.704 0.0062739 eukaryotic translation initiation factor 4 gamma, 1 RAB31 7.39 6.903 5.981 8.686 7.448 8.338 2.705 0.0284138 RAB31, member RAS oncogene family TCEB2 9.405 8.716 8.529 10.316 10.153 10.133 2.707 0.0087172 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) NUBP1 5.536 4.278 4.377 6.485 5.759 5.814 2.707 0.027493 nucleotide binding protein 1 (MinD homolog, E. coli) HIF1AN 6.048 4.447 4.785 6.372 6.143 6.222 2.707 0.0475438 hypoxia inducible factor 1, alpha subunit inhibitor DSCR3 4.437 5.174 3.308 5.416 6.005 5.874 2.708 0.0257981 Down syndrome critical region gene 3 TRIAP1 7.095 6.415 5.935 7.855 7.686 8.103 2.713 0.0110782 TP53 regulated inhibitor of apoptosis 1 ACADM 5.308 4.068 4.392 6.038 5.922 5.509 2.715 0.024594 acyl-CoA dehydrogenase, C-4 to C-12 straight chain IFRD2 10.183 8.603 9.387 11.308 10.673 10.828 2.716 0.0143936 interferon-related developmental regulator 2 MID1IP1 5.567 5.029 5.322 6.14 7.186 6.763 2.717 0.0103427 MIDI interacting protein 1 (gastrulation specific G12 homolog (zebrafish)) LOC1001295 4.236 4.369 3.519 5.811 5.28 5.539 2.718 0.0056858 No description 50 HOXC8 5.711 3.825 4.445 5.887 6.37 5.739 2.718 0.0386664 homeobox C8 PRDM2 7.424 6.069 6.853 8.092 8.785 8.296 2.719 0.0092223 PR domain containing 2, with ZNF domain MLLT1 9.268 7.603 8.589 10.297 10.032 9.985 2.719 0.0115103 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 IRAKI 8.77 7.74 8.773 10.218 9.38 9.31 2.721 0.0332818 interleukin-1 receptor-associated kinase 1 IGSF22 0.545 0.817 1.083 4.12 2.261 1.936 2.722 0.0117457 immunoglobulin superfamily, member 22 CHERP 9.24 7.885 8.485 10.112 9.93 9.907 2.722 0.0117772 calcium homeostasis endoplasmic reticulum protein RGS12 7.648 7.39 8.712 9.248 9.263 8.835 2.723 0.0310575 regulator ofG-protein signaling 12 TFCP2L1 2.963 3.33 3.107 4.944 4.329 4.553 2.724 0.0033476 transcription factor CP2-like 1 CSTF3 4.855 5.356 5.113 6.351 6.649 6.561 2.727 0.0030801 cleavage stimulation factor, 3′ pre-RNA, subunit 3, 77kDa C7orf13 3.372 2.39 2.486 3.636 4.82 3.966 2.728 0.0203026 chromosome 7 open reading frame 13 COL17A1 7.955 9.716 8.783 9.72 10.24 10.233 2.731 0.0422558 collagen, type XVII, alpha 1 RPL24 12.191 11.057 10.605 12.594 12.316 12.507 2.732 0.0402704 ribosomal protein L24 HOMEZ 7.961 6.871 6.997 8.505 8.627 8.322 2.735 0.0208757 homeobox and leucine zipper encoding WDR76 4.266 3.022 2.859 4.395 4.475 4.55 2.738 0.0485419 WD repeat domain 76 C19orf24 4.632 4.111 3.95 6.532 4.876 5.564 2.739 0.0228504 chromosome 19 open reading frame 24 OSGEPL1 1.83 1.03 2.509 3.069 3.521 3.286 2.743 0.0128704 O-sialoglycoprotein endopeptidase-like 1 LOC283050 0.589 0.464 0.888 2.689 1.92 1.936 2.744 0.0044902 No description PDRG1 6.796 5.014 5.807 7.046 7.263 7.32 2.744 0.0300866 p53 and DNA-damage regulated 1 FAM174A 5.842 5.044 4.023 7.206 6.463 6.501 2.747 0.0117965 family with sequence similarity 174, member A SCAMP2 4.881 3.723 3.532 6.095 4.991 5.764 2.748 0.015934 secretory carrier membrane protein 2 POLR2L 9.667 8.566 8.206 10.525 9.977 10.027 2.753 0.022273 polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa C22orf26 0.323 0.464 1.042 2.073 1.546 2.504 2.755 0.0097381 chromosome 22 open reading frame 26 KCNJ11 2.621 2.392 3.219 4.735 3.855 3.974 2.756 0.0102611 potassium inwardly-rectifying channel, subfamily J, member 11 NFKBIB 9.434 7.866 8.107 10.019 9.448 9.569 2.756 0.0439679 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta TBCCD1 3.884 3.08 3.207 5.393 4.671 4.333 2.757 0.0136267 TBCC domain containing 1 ZNF500 3.598 2.393 2.567 4.29 4.026 4.031 2.758 0.0202826 zinc finger protein 500 SNORD95 −0.192 −0.177 0.925 1.267 2.39 1.908 2.76 0.0099213 small nucleolar RNA, C/D box 95 SRC 6.854 5.689 5.637 7.317 7.362 7.102 2.76 0.027767 v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) MVK 4.924 3.469 3.769 5.107 5.491 5.234 2.76 0.0326472 mevalonate kinase POLN 1.684 1.747 2.6 3.212 3.29 3.163 2.761 0.0151914 polymerase (DNA directed) nu LTA 0.554 1.936 2.048 3.156 3.513 2.316 2.761 0.0267132 lymphotoxin alpha (TNF superfamily, member 1) ZC3HAV1L 1.407 0.903 1.52 2.987 2.518 2.415 2.763 0.0067232 zinc finger CCCH-type, antiviral 1-like SHQ1 6.286 4.58 5.068 6.545 6.513 6.536 2.765 0.0408407 SHQ1 homolog (S. cerevisiae) ZNF646 4.352 2.807 2.876 4.604 4.678 4.274 2.765 0.0492681 zinc finger protein 646 KIAA1244 5.052 4.16 4.077 5.696 6.172 5.546 2.767 0.0123882 KIAA1244 SDR42E1 2.323 1.176 1.767 3.791 2.324 3.389 2.767 0.0268033 short chain dehydrogenase/reductase family 42E, member 1 C16orf88 3.586 3.209 1.886 5.022 4.438 4.679 2.77 0.0084589 chromosome 16 open reading frame 88 TNPO3 5.913 5.113 5.397 6.869 7.063 6.776 2.773 0.0050061 transportin 3 MAK16 7.695 6.694 7.056 8.746 8.324 8.528 2.774 0.0091629 MAK16 homolog (S. cerevisiae) CPNE9 0.162 0.701 1.793 2.78 2.819 1.635 2.775 0.0256407 copine family member IX PPP1R14B 1.374 2.52 1.334 3.868 2.807 3.444 2.777 0.0113479 protein phosphatase 1, regulatory (inhibitor) subunit 14B HARS 7.886 6.631 6.587 8.635 8.06 8.33 2.778 0.0247764 histidyl-tRNA synthetase PDE6G 2.59 1.568 1.637 2.508 4.063 3.172 2.778 0.0370781 phosphodiesterase 6G, cGMP-specific, rod, gamma C8orf38 1.992 1.318 0.327 3.469 2.342 2.528 2.782 0.0209265 chromosome 8 open reading frame 38 CLDN3 3.932 4.939 3.112 4.615 6.415 5.331 2.782 0.0474472 claudin 3 TRIM16L 3.514 3.721 2.888 4.776 5.059 4.993 2.788 0.0036954 tripartite motif-containing 16-like ST14 5.637 5.78 5.167 6.648 7.401 6.998 2.79 0.0052629 suppression of tumorigenicity 14 (colon carcinoma) CHRNB1 5.842 5.701 4.473 6.845 7.325 6.836 2.795 0.0087293 cholinergic receptor, nicotinic, beta 1 (muscle) GYLTL1B 6.107 6.499 7.441 8.402 7.978 7.982 2.795 0.0137741 glycosyltransferase-like 1 B SMCR8 6.654 4.96 5.674 7.159 7.212 7.046 2.799 0.0234364 Smith-Magenis syndrome chromosome region, candidate 8 FLAD1 6.883 5.559 5.442 7.632 7.043 7.015 2.799 0.034375 FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae) NAGS 3.767 3.229 3.293 5.862 4.208 4.779 2.8 0.0168384 N-acetylglutamate synthase ITGB1BP2 1.936 2.326 2.132 3.537 4.156 3.423 2.801 0.0033548 integrin beta 1 binding protein (melusin) 2 USP51 5.101 5.108 3.879 6.594 6.357 5.754 2.801 0.0136195 ubiquitin specific peptidase 51 THOC6 7.401 8.133 7.177 8.664 9.149 8.904 2.803 0.0111226 THO complex 6 homolog (Drosophila) HPX 3.885 3.43 4.694 5.372 5.539 5.268 2.803 0.0127602 hemopexin STK39 4.537 6.013 5.279 7.5 6.301 6.23 2.804 0.0329949 serine threonine kinase 39 PDCD5 8.423 7.577 8.365 9.911 9.183 9.55 2.805 0.009369 programmed cell death 5 PPM1G 10.585 9.225 9.415 11.725 10.715 10.903 2.805 0.0274787 protein phosphatase, Mg2+/Mn2+ dependent, 1G FUNDC2 4.701 2.75 3.481 5.117 4.97 4.749 2.808 0.041984 FUN14 domain containing 2 LOC1001328 4.244 2.854 2.548 4.698 4.347 4.252 2.814 0.0465264 No description 32 TRPM8 4.6 3.492 4.594 5.719 5.863 6.097 2.822 0.0055928 transient receptor potential cation channel, subfamily M, member 8 HSPB1 6.041 5.568 4.73 5.829 7.676 7.065 2.822 0.041926 heat shock 27kDa protein 1 PRPSAP2 5.335 4.573 4.565 6.606 6.282 6.062 2.823 0.0056715 phosphoribosyl pyrophosphate synthetase- associated protein 2 CFDP1 6.553 6.018 6.263 7.916 7.436 8.051 2.825 0.0035895 craniofacial development protein 1 ZNF384 7.035 6.069 6.296 7.774 7.831 7.794 2.825 0.0093861 zinc finger protein 384 NAT14 5.066 3.968 3.794 5.863 5.951 5.293 2.828 0.0164442 N-acetyltransferase 14 (GCN5-related, putative) QTRTD1 5.698 6.002 5.268 7.163 7.199 7.383 2.829 0.0024283 queuine tRNA-ribosyltransferase domain containing 1 JRKL 3.188 2.701 2.262 4.102 4.689 3.8 2.829 0.0093418 jerky homolog-like (mouse) MGAM 0.825 1.568 1.126 2.886 1.894 3.068 2.829 0.0138592 maltase-glucoamylase (alpha-glucosidase) EPCAM 4.442 5.824 4.899 6.4 6.444 6.283 2.83 0.0188696 epithelial cell adhesion molecule CCNB1IP1 3.799 3.886 4.176 5.437 5.3 5.394 2.831 0.0018745 cyclin B1 interacting protein 1 WNT5B 3.434 3.375 2.928 5.805 4.394 4.876 2.831 0.0056214 wingless-type MMTV integration site family, member 5B OR8D1 4.05 3.38 3.476 5.136 4.911 4.981 2.837 0.0049224 olfactory receptor, family 8, subfamily D, member 1 GPR135 2.073 0.554 −0.648 3.329 2.06 1.878 2.84 0.0379416 G protein-coupled receptor 135 C17orf69 3.516 3.693 3.322 5.235 5.013 4.828 2.841 0.0019031 chromosome 17 open reading frame 69 DAXX 9.502 8.252 8.152 9.764 9.938 9.659 2.841 0.0387694 death-domain associated protein ZNF587 4.919 4.395 5.013 6.052 6.519 6.196 2.842 0.0039 zinc finger protein 587 FAM185A 3.076 2.601 2.299 4.579 4.294 3.806 2.842 0.0050862 family with sequence similarity 185, member A S100A14 9.75 8.56 7.104 9.871 10.2 10.067 2.842 0.0387265 S100 calcium binding protein A14 FLJ10038 5.667 5.154 6.117 7.369 7.175 7.095 2.843 0.0042656 No description FAM40B 2.222 2.463 3.076 3.972 3.789 4.237 2.845 0.0067869 family with sequence similarity 40, member B GNA11 8.814 7.668 7.296 9.153 9.419 9.178 2.848 0.0241683 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) ZNF273 3.163 2.885 3.606 4.675 4.894 4.652 2.851 0.0032117 zinc finger protein 273 SLC37A2 2.439 2.427 2.263 3.939 4.082 3.593 2.852 0.0019775 solute carrier family 37 (glycerol-3-phosphate transporter), member 2 CILP2 5.703 4.167 4.663 6.17 6.755 6.176 2.853 0.0153159 cartilage intermediate layer protein 2 FITM1 3.242 1.471 2.318 3.933 3.832 3.457 2.856 0.0262116 fat storage-inducing transmembrane protein 1 LOC1001286 4.603 4.25 3.911 6.012 5.767 5.576 2.861 0.0033977 No description 75 HSP90AA1 12.851 11.785 11.099 13.123 13.379 13.303 2.863 0.0275639 heat shock protein 90kDa alpha (cytosolic), class A member 1 SUN3 4.142 2.343 3.039 4.557 4.239 4.82 2.864 0.0310939 Sad1 and UNC84 domain containing 3 COL2A1 3.847 4.718 4.644 5.671 6.238 5.853 2.868 0.0061358 collagen, type II, alpha 1 DGAT2 0.554 0.886 2.277 3.521 2.829 2.076 2.872 0.0280353 diacylglycerol O-acyltransferase 2 TRNT1 5.078 4.851 5.32 6.615 6.376 6.614 2.877 0.0022952 tRNA nucleotidyl transferase, CCA-adding, 1 ZMAT3 7.365 7.163 8.139 9.241 8.966 8.69 2.883 0.0094663 zinc finger, matrin-type 3 LOC678655 7.014 7.144 8.394 8.657 8.672 8.989 2.884 0.0287916 No description MYBBP1A 9.135 9.017 9.09 10.87 10.085 10.619 2.886 0.0043522 MYB binding protein (P160) 1a SAMD10 0.924 1.075 1.46 2.903 2.99 1.92 2.888 0.0104436 sterile alpha motif domain containing 10 FBXL15 6.469 5.23 5.59 7.12 7.235 7.07 2.888 0.0127459 F-box and leucine-rich repeat protein 15 CDKN2B 4.43 2.832 3.865 4.905 5.467 5.396 2.889 0.0147235 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) UPK3B 5.297 4.072 3.544 5.474 5.806 5.607 2.897 0.031843 uroplakin 3B BYSL 8.552 7.094 7.363 8.898 8.708 8.907 2.897 0.0383509 bystin-like PADI3 −0.264 0.78 0.422 1.459 1.773 2.316 2.899 0.0088588 peptidyl arginine deiminase, type III PEG3AS 5.315 4.046 4.778 5.983 6.796 6.317 2.906 0.0078415 No description RPP21 8.536 7.556 7.411 9.476 9.178 8.95 2.906 0.014345 ribonuclease P/MRP 21 kDa subunit VWA5B1 1.44 1.219 −1.775 2.981 2.725 2.651 2.911 0.0129498 von Willebrand factor A domain containing 5B1 PYY2 3.161 3.102 1.408 4.703 3.998 4.557 2.913 0.0104071 peptide YY, 2 (seminalplasmin) NCRNA00183 4.47 3.569 3.812 5.306 5.82 5.356 2.915 0.0053424 non-protein coding RNA 183 MTFMT 3.842 3.754 3.747 5.298 5.412 5.195 2.916 0.0007441 mitochondrial methionyl-tRNA formyltransferase LASS2 8.466 6.609 7.291 8.974 8.837 8.754 2.92 0.0275424 LAG1 homolog, ceramide synthase 2 LOC644669 3.219 2.343 2.706 4.347 4.556 3.891 2.923 0.006198 No description DLG5 6.883 6.081 8.477 8.872 8.431 8.426 2.923 0.0476061 discs, large homolog 5 (Drosophila) NDUFA8 6.907 5.954 5.797 7.395 7.812 7.502 2.924 0.0139257 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa DKFZp686O2 3.964 3.134 4.197 5.808 4.683 5.318 2.925 0.0136553 No description 4166 ZC3H3 6.908 5.008 5.62 7.692 7.168 7.116 2.925 0.0261193 zinc finger CCCH-type containing 3 MGC16384 2.028 1.54 2.056 3.267 3.608 3.147 2.931 0.0036667 No description CSF1 5.265 4.29 5.23 6.176 6.819 6.441 2.935 0.0072483 colony stimulating factor 1 (macrophage) ANKRD11 9.798 8.726 8.887 10.611 10.82 10.283 2.941 0.0104708 ankyrin repeat domain 11 G10orf10 6.885 7.684 7.004 8.442 9.065 8.807 2.943 0.0045525 chromosome 10 open reading frame 10 CROCCL2 2.817 2.317 3.599 4.089 4.501 4.377 2.948 0.0129162 No description VPS4A 7.236 5.875 5.96 8.234 7.434 7.643 2.948 0.0216749 vacuolar protein sorting 4 homolog A (S. cerevisiae) NCRNA00116 7.127 6.196 6.285 8.687 7.449 8.02 2.949 0.0136124 non-protein coding RNA 116 FTL 13.854 11.894 12.248 14.27 13.808 13.808 2.949 0.049507 ferritin, light polypeptide RASAL2 6.976 7.241 7.499 9.06 8.388 8.971 2.951 0.0035458 RAS protein activator like 2 TRIM44 6.009 5.238 5.583 7.078 7.146 7.168 2.956 0.0032317 tripartite motif-containing 44 EPS8L1 4.081 4.508 4.339 5.923 5.905 5.658 2.961 0.00174 EPS8-like 1 ANAPCI 5.919 5.515 4.984 6.864 7.485 6.892 2.961 0.0050447 anaphase promoting complex subunit 1 C17orf67 2.118 1.374 1.033 3.684 2.06 3.035 2.961 0.0287379 chromosome 17 open reading frame 67 C14orf21 4.002 2.224 2.616 4.844 4.182 3.968 2.962 0.0355913 chromosome 14 open reading frame 21 LOH12CR2 4.214 3.713 3.192 4.917 5.425 5.28 2.963 0.0067668 loss of heterozygosity, 12, chromosomal region 2 RPL13P5 4.202 3.677 3.122 5.305 4.689 5.483 2.963 0.0100286 ribosomal protein L13 pseudogene 5 WDR8 4.648 4.493 3.652 6.215 5.496 5.368 2.963 0.0132468 WD repeat domain 8 SDC4 10.655 11.007 10.398 12.316 11.968 12.385 2.969 0.0029491 syndecan 4 SEC1 4.131 2.74 3.444 4.935 5.105 5.015 2.97 0.0081427 No description FAM22A 3.615 0.93 2.621 4.487 4.1 4.192 2.971 0.0203427 family with sequence similarity 22, member A C1orf103 3.294 2.731 2.998 4.488 4.785 4.57 2.972 0.0017257 chromosome 1 open reading frame 103 ATRIP 5.917 4.437 4.579 6.399 6.305 6.011 2.976 0.0326959 ATR interacting protein ARHGAP39 3.908 3.802 4.183 5.578 5.444 5.483 2.979 0.0012628 Rho GTPase activating protein 39 SCNN1A 3.809 4.901 3.222 5.02 6.394 5.385 2.981 0.0215661 sodium channel, nonvoltage-gated 1 alpha PRKAG1 5.494 4.803 4.093 6.661 6.233 6.38 2.983 0.0078343 protein kinase, AMP-activated, gamma 1 non- catalytic subunit SPTBN5 7.158 6.411 6.686 7.656 8.906 8.265 2.987 0.0105788 spectrin, beta, non-erythrocytic 5 BCL9L 10.68 9.129 9.564 11.143 11.349 11.071 2.988 0.0197732 B-cell CLL/lymphoma 9-like MRPS27 3.264 2.833 2.449 5.059 4.278 4.03 2.993 0.0068083 mitochondrial ribosomal protein S27 NTNG2 0.478 1.455 0.757 3.581 2.206 2.06 2.995 0.0120798 netrin G2 DHX33 5.6 5.726 4.64 7.309 6.405 7.021 2.997 0.0092931 DEAH (Asp-Glu-Ala-His) box polypeptide 33 RPS17 12.979 12.598 12.027 14.554 14.158 14.183 3 0.0026043 ribosomal protein S17 PTGES2 2.045 1.134 2.006 3.63 3.19 3.052 3 0.0060428 prostaglandin E synthase 2 PPP1R3C 4.376 5.096 5.333 7.286 5.532 6.683 3.003 0.0204464 protein phosphatase 1, regulatory (inhibitor) subunit 3C ANKRD13B 6.793 6.004 6.96 8.381 8.401 8.232 3.005 0.0025971 ankyrin repeat domain 13B SCRIB 6.335 5.609 5.862 7.437 7.923 7.434 3.005 0.0027266 scribbled homolog (Drosophila) TBC1D26 0.251 0.96 1.301 3.021 2.548 1.305 3.005 0.028949 TBC1 domain family, member 26 LOC1001281 −0.104 0.522 0.842 2.548 1.49 2.031 3.018 0.0079524 No description 64 GUCA1B 3.425 4.181 2.313 5.775 4.951 4.733 3.018 0.0115833 guanylate cyclase activator 1B (retina) TMEM5 4.96 4.039 3.474 6.143 5.3 5.633 3.018 0.0151649 transmembrane protein 5 CRABP2 10.399 8.422 9.233 10.828 10.928 10.671 3.02 0.0266559 cellular retinoic acid binding protein 2 TBCA 9.022 9.354 8.078 10.95 10.295 10.404 3.022 0.0060714 tubulin folding cofactor A PES1 9.234 7.499 7.511 9.991 9.095 9.186 3.023 0.0466617 pescadillo homolog 1, containing BRCT domain (zebrafish) TIMM16 5.379 5.448 3.84 7.045 5.946 6.452 3.024 0.021031 No description ELK1 8.365 6.888 7.244 8.909 8.566 8.842 3.027 0.0277034 ELK1, member of ETS oncogene family SCAMP3 8.081 6.818 7.101 8.748 8.684 8.7 3.029 0.0137984 secretory carrier membrane protein 3 MEX3D 7.716 6.122 7.47 8.486 9.317 8.893 3.034 0.0093203 mex-3 homolog D (C. elegans) TRAF2 6.82 5.329 5.07 7.053 6.93 6.898 3.034 0.0474401 TNF receptor-associated factor 2 GPATCH4 9.497 7.956 9.395 11.099 10.404 10.804 3.037 0.008192 G patch domain containing 4 WDR4 6.025 4.134 4.677 6.382 6.28 6.159 3.037 0.0367568 WD repeat domain 4 BTF3 5.381 5.229 5.64 7.015 6.833 7.171 3.04 0.0014352 basic transcription factor 3 RPPH1 3.036 3.044 2.229 3.669 4.855 4.642 3.043 0.0094341 ribonuclease P RNA component H1 TMEM39B 6.607 4.873 5.557 7.216 7.165 6.767 3.047 0.0274415 transmembrane protein 39B UCN 1.908 1.893 2.099 4.53 3.467 3.517 3.049 0.0026436 urocortin HYLS1 4.423 3.431 3.064 4.673 5.924 5.997 3.051 0.0087651 hydrolethalus syndrome 1 CLIC3 2.968 1.715 1.219 3.158 4.578 3.128 3.053 0.0255584 chloride intracellular channel 3 NME1 9.562 8.047 8.566 10.653 10.132 10.177 3.056 0.0112599 non-metastatic cells 1, protein (NM23A) expressed in LSR 8.487 7.254 6.429 9.689 8.866 8.635 3.056 0.0217987 lipolysis stimulated lipoprotein receptor FOXP3 1.783 0.283 −0.104 2.629 1.556 1.898 3.063 0.0451155 forkhead box P3 UBE2J2 9.409 7.746 8.329 10.275 9.944 9.627 3.064 0.0211004 ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast) TMEM169 2.248 1.366 1.589 3.222 2.983 3.535 3.069 0.0056357 transmembrane protein 169 CCNT1 4.461 3.124 3.348 4.884 4.967 5.135 3.071 0.0181563 cyclin T1 CCDC127 5.397 4.282 3.86 6.312 5.902 5.86 3.072 0.0149281 coiled-coil domain containing 127 C9orf114 5.36 4.111 3.922 6.646 5.541 6.137 3.073 0.0142141 chromosome 9 open reading frame 114 TNFSF11 0.251 −0.046 0.422 2.026 2.003 1.576 3.078 0.0016642 tumor necrosis factor (ligand) superfamily, member 11 BANF1 8.324 7.147 7.021 9.294 8.893 8.645 3.081 0.0160192 barrier to autointegration factor 1 TLR9 3.3 1.741 1.613 4.029 3.363 3.372 3.097 0.0351062 toll-like receptor 9 IER3 11.255 11.384 11.193 12.886 13.092 12.823 3.098 0.000631 immediate early response 3 KCNMA1 8.107 9.191 7.992 10.467 9.624 9.975 3.1 0.0101889 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 PTDSS2 6.874 5.323 5.935 7.746 7.572 7.279 3.111 0.0152887 phosphatidylserine synthase 2 FAM160A1 5.248 5.742 6.391 7.335 7.465 7.38 3.113 0.0049918 family with sequence similarity 160, member A1 BNIP1 5.95 4.991 4.624 6.703 6.283 6.631 3.116 0.0177349 BCL2/adenovirus E1B 19kDa interacting protein 1 HAGHL 3.521 5.04 5.009 6.234 6.682 6.143 3.12 0.0076218 hydroxyacylglutathione hydrolase-like ZNF419 3.464 2.908 3.233 5.238 4.479 4.875 3.122 0.0028583 zinc finger protein 419 SNORA80 2.219 1.783 1.715 3.863 3.025 3.661 3.127 0.0039071 small nucleolar RNA, H/ACA box 80 TTC22 1.303 0.924 1.388 3.477 2.569 2.614 3.129 0.0038785 tetratricopeptide repeat domain 22 LOC1003037 2.602 1.44 1.762 4.248 2.835 4.24 3.13 0.0097102 No description 28 ADRBK1 7.599 5.825 6.278 8.07 8.053 7.472 3.131 0.0406682 adrenergic, beta, receptor kinase 1 TSN 6.631 5.431 4.87 7.459 6.595 7.078 3.132 0.0310324 translin C17orf100 1.911 2.701 2.114 3.762 4.018 3.73 3.133 0.0031545 chromosome 17 open reading frame 100 GSR 2.722 1.741 2.821 3.702 4.469 4.162 3.133 0.0061573 glutathione reductase LOC1002722 −0.104 0.994 0.589 2.949 2.236 0.814 3.133 0.0370065 No description 16 SPNS2 7.69 6.432 5.745 8.39 7.952 8.08 3.134 0.0227588 spinster homolog 2 (Drosophila) MYLPF 3.175 2.17 2.674 4.824 4.495 3.336 3.138 0.017312 myosin light chain, phosphorylatable, fast skeletal muscle C21orf56 2.949 3.333 3.531 5.025 5.184 4.345 3.145 0.0045883 chromosome 21 open reading frame 56 LOC1001280 4.179 3.338 4.294 5.948 5.699 5.54 3.147 0.0027195 No description 03 NMUR1 3.573 2.798 4.833 5.49 5.227 4.983 3.147 0.0268985 neuromedin U receptor 1 SMPD4 0.323 0.701 0.251 1.908 2.053 2.02 3.153 0.0014281 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) SUSD5 4.283 4.111 4.174 5.834 6.227 5.732 3.16 0.0008879 sushi domain containing 5 FAM200A 3.52 3.088 4.369 5.18 5.198 4.753 3.16 0.0150304 family with sequence similarity 200, member A GEMIN6 3.512 1.797 2.27 3.931 3.909 4.207 3.163 0.0189762 gem (nuclear organelle) associated protein 6 PLD6 4.242 3.277 4.962 5.904 5.637 6.047 3.164 0.0095357 phospholipase D family, member 6 IRX1 10.297 9.258 9.024 10.726 11.143 10.921 3.166 0.0145267 iroquois homeobox 1 UGT2B10 1.037 0.78 1.062 3.156 2.414 2.704 3.174 0.0014073 UDP glucuronosyltransferase 2 family, polypeptide B10 HCST 2.956 2.202 1.126 3.869 4.211 3.702 3.177 0.0085133 hematopoietic cell signal transducer METTL2B 3.645 3.017 3.181 5.061 5.158 4.686 3.179 0.0020133 methyltransferase like2B MLNR 1.091 0.224 −0.648 2.548 1.894 1.408 3.181 0.0140459 motilin receptor APOA1 4.512 3.856 3.924 5.594 6.377 5.443 3.182 0.0042584 apolipoprotein A-l PDZK1IP1 3.645 2.497 3.076 4.008 6.225 4.747 3.185 0.0147163 PDZK1 interacting protein 1 GMEB1 5.747 3.952 4.356 6.527 5.803 6.032 3.195 0.0288574 glucocorticoid modulatory element binding protein 1 AIM1L 3.152 2.268 2.487 4.783 4.164 4.088 3.197 0.0039429 absent in melanoma 1 -like PHB 5.874 4.139 5.159 6.952 6.836 6.547 3.198 0.0097582 prohibitin XCR1 0.609 −0.887 0.925 2.217 2.39 2.288 3.202 0.0047829 chemokine (C motif) receptor 1 TOMM6 8.269 7.187 7.163 9.662 8.843 8.979 3.203 0.0089576 translocase of outer mitochondrial membrane 6 homolog (yeast) ZNF765 6.178 4.983 5.184 7.292 6.752 6.87 3.218 0.0096816 zinc finger protein 765 LCN2 0.162 0.323 1.239 2.157 2.928 1.846 3.225 0.0070874 lipocalin 2 NUPL2 3.486 2.861 2.339 5.123 4.553 4.248 3.23 0.0054075 nucleoporin like 2 ZNF836 3.564 3.415 3.286 4.474 5.171 5.256 3.232 0.0037848 zinc finger protein 836 DLGAP3 2.064 0.93 1.239 3.026 2.623 3.187 3.233 0.0080811 discs, large (Drosophila) homolog-associated protein 3 CNTFR 4.55 3.228 3.297 4.981 6.014 4.991 3.235 0.0143378 ciliary neurotrophic factor receptor MGRN1 6.93 5.514 5.961 8.039 7.219 7.658 3.242 0.0152815 mahogunin, ring finger 1 C8orf73 5.452 4.769 3.966 6.896 6.467 6.463 3.243 0.0045739 chromosome 8 open reading frame 73 FBLL1 2.546 3.287 2.602 4.244 4.654 4.623 3.244 0.0025335 fibrillarin-like 1 BCL7C 6.181 4.094 5.07 6.794 6.772 6.624 3.254 0.01911 B-cell CLL/lymphoma 7C ATP6VOB 10.114 8.912 9 10.903 10.69 10.703 3.256 0.0123081 ATPase, H+ transporting, lysosomal 21kDa, VO subunit b C17orf91 3.791 3.614 2.976 4.211 5.684 5.317 3.257 0.0125292 chromosome 17 open reading frame 91 CORO7 6.456 5.177 5.257 7.77 7.495 6.881 3.259 0.0077928 coronin 7 FBXO10 3.472 3.384 3.2 5.513 4.906 4.985 3.263 0.0011955 F-box protein 10 MGC70857 5.478 3.893 4.409 6.628 5.92 6.118 3.269 0.0121142 No description C9orf142 4.872 5.162 4.342 6.872 6.242 6.453 3.272 0.0029291 chromosome 9 open reading frame 142 HINT1 6.002 5.987 6.063 7.65 7.928 7.713 3.274 0.0004214 histidine triad nucleotide binding protein 1 TMPRSS11B 0.825 0.623 0.478 2.189 2.236 3.068 3.274 0.0019632 TMPRSS11B N terminal-like NL CCNA1 3.46 3.598 3.445 5.31 5.191 5.156 3.276 0.0003928 cyclin A1 PTAFR 3.212 1.958 2.249 4.578 3.672 3.998 3.281 0.0101295 platelet-activating factor receptor LOC1001339 3.156 3.454 3.095 4.755 5.432 4.871 3.284 0.0015683 No description 91 MKI67IP 7.045 6.42 6.508 8.696 8.137 8.421 3.287 0.0018173 MKI67 (FHA domain) interacting nucleolar phosphoprotein HIST1H2BG 0.525 0.552 −0.104 1.641 2.269 2.153 3.287 0.0029219 histone cluster 1, H2bg NDUFA10 3.747 2.893 1.605 4.942 4.613 4.434 3.295 0.010289 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10. 42kDa SPTBN4 4.537 4.288 4.141 6.092 5.891 6.009 3.296 0.0007942 spectrin, beta, non-erythrocytic 4 SLC39A3 6.624 4.766 4.915 7.083 6.68 6.488 3.298 0.0468191 solute carrier family 39 (zinc transporter), member 3 LOC1001255 −0.264 0.162 0.825 1.459 2.166 2.008 3.3 0.0060213 No description 56 ZNF528 4.053 3.297 2.605 5.105 4.565 5.02 3.3 0.0104143 zinc finger protein 528 TAF1A 1.587 2.292 0.814 3.511 2.539 3.622 3.304 0.0134306 TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa ASNA1 8.086 6.467 6.889 9.124 8.613 8.583 3.305 0.0125041 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) PVT1 8.276 9.216 10.759 11.334 10.399 10.941 3.305 0.0499549 Pvt1 oncogene (non-protein coding) AMZ1 5.023 3.981 4.909 6.265 6.748 6.281 3.306 0.0036038 archaelysin family metallopeptidase 1 E4F1 2.849 1.645 1.801 3.846 3.68 3.371 3.308 0.0092781 E4F transcription factor 1 EIF4EBP1 6.754 6.923 5.563 8.649 7.291 8.031 3.31 0.019155 eukaryotic translation initiation factor 4E binding protein 1 GRIN1 −0.104 −0.529 1.033 2.048 1.198 2.484 3.311 0.012107 glutamate receptor, ionotropic, N-methyl D- aspartate 1 LOC286467 4.422 3.582 4.031 5.759 5.871 5.595 3.313 0.0020419 No description ARRDC5 4.307 3.906 3.613 5.341 5.652 5.663 3.313 0.0023796 arrestin domain containing 5 L1CAM 1.456 1.269 1.297 4.091 3.001 3.017 3.32 0.0018602 L1 cell adhesion molecule ZNF324 2.333 1.748 1.618 3.336 3.812 4.065 3.322 0.002165 zinc finger protein 324 CHD5 2.385 2.429 2.269 4.161 4.118 4.043 3.323 0.0003012 chromodomain helicase DNA binding protein 5 RNF216L 0.986 1.297 0.96 2.722 3.205 2.132 3.33 0.0048043 ring finger protein 216-like FCN3 4.008 2.36 2.717 4.697 5.03 4.096 3.332 0.0183137 ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen) PRF1 3.934 3.287 4.668 5.671 6.026 5.544 3.334 0.0049989 perforin 1 (pore forming protein) MARVELD2 1.506 1.963 1.844 3.701 3.564 3.329 3.336 0.0009523 MARVEL domain containing 2 TMEM80 5.84 4.817 6.06 6.558 7.982 7.197 3.343 0.0137247 transmembrane protein 80 LLPH 7.352 5.763 5.786 8.216 7.804 7.506 3.348 0.0197224 LLP homolog, long-term synaptic facilitation (Aplysia) C1orf113 2.721 1.858 2.323 3.727 4.402 4.068 3.352 0.0028196 chromosome 1 open reading frame 113 FAM171A2 3.609 2.397 2.64 4.386 5.184 4.218 3.355 0.008074 family with sequence similarity 171, member A2 PRSS22 9.112 7.761 5.282 10.565 9.507 9.189 3.355 0.0246712 protease, serine, 22 SLC38A7 3.664 1.951 2.358 4.106 4.004 4.655 3.358 0.0162724 solute carrier family 38, member 7 MOSC1 3.365 1.709 1.908 4.397 3.459 4.166 3.365 0.0155234 MOCO sulphurase C-terminal domain containing 1 ENTPD2 4.904 6.009 4.247 7.019 6.659 6.567 3.375 0.011247 ectonucleoside triphosphate diphosphohydrolase 2 TBL2 5.208 3.629 3.24 5.675 4.996 5.825 3.378 0.0338148 transducin (beta)-like 2 ALDH1A3 4.034 3.134 5.001 5.983 5.078 5.791 3.38 0.0220841 aldehyde dehydrogenase 1 family, member A3 TOP2A 2.572 3.933 3.19 5.414 4.333 5.076 3.388 0.0095643 topoisomerase (DNA) II alpha 170kDa GAL3ST1 3.942 3.233 2.756 4.995 5.441 4.873 3.392 0.0039787 galactose-3-O-sulfotransferase 1 TTC27 5.13 3.221 4.002 6.093 5.515 5.765 3.392 0.0147907 tetratricopeptide repeat domain 27 DEPDC7 2.607 2.597 1.998 3.493 4.45 4.361 3.396 0.0045453 DEP domain containing 7 MT1L 3.484 1.547 4.607 4.998 6.346 5.249 3.397 0.0151985 metallothionein 1L (gene/pseudogene) LDHAL6A 0.162 0.464 0.17 0.762 2.261 1.936 3.401 0.0200265 lactate dehydrogenase A-like 6A UGCG 7.001 6.612 6.435 8.378 8.41 8.377 3.402 0.001066 UDP-glucose ceramide glucosyltransferase WNT7B 3.752 2.146 1.679 3.69 4.29 3.913 3.403 0.0369779 wingless-type MMTV integration site family, member 7B RGP1 2.296 2.494 1.793 4.307 3.829 3.56 3.404 0.0031402 RGP1 retrograde golgi transport homolog (S. cerevisiae) SAAL1 3.611 2.657 3.033 5.382 3.938 5.089 3.414 0.0103713 serum amyloid A-like 1 CBFB 8.194 6.062 7.04 8.53 8.929 8.811 3.415 0.0187072 core-binding factor, beta subunit SNW1 5.232 4.389 4.314 6.449 6.14 6.165 3.425 0.0043271 SNW domain containing 1 LOC645332 2.798 1.828 1.315 4.156 3.093 3.668 3.429 0.0122895 No description RGPD1 0.625 1.818 2.489 4.679 2.008 3.597 3.43 0.0404021 RANBP2-like and GRIP domain containing 1 RHD 6.252 5.438 5.465 7.346 7.383 7.219 3.436 0.0035179 Rh blood group, D antigen B4GALT2 8.296 6.962 7.454 9.736 8.895 9.236 3.441 0.0072741 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 ZSCAN1 1.374 0.78 0.631 2.601 2.414 2.798 3.442 0.002331 zinc finger and SCAN domain containing 1 ARRDC1 5.694 4.113 5.184 7.477 6.759 6.031 3.443 0.0143722 arrestin domain containing 1 ARHGAP11A 4.517 3.425 3.036 4.916 5.208 5.25 3.443 0.0152272 Rho GTPase activating protein 11A FLJ36777 0.838 0.967 1.082 2.868 2.408 2.763 3.448 0.0009237 No description NFAM1 2.677 1.709 1.631 3.677 3.422 3.507 3.462 0.0066538 NFAT activating protein with ITAM motif 1 CKM 0.478 1.366 0.543 3.222 1.145 2.336 3.465 0.0388259 creatine kinase, muscle RAB36 3.2 2.685 2.432 4.848 4.227 4.584 3.47 0.0022108 RAB36, member RAS oncogene family NUP62 8.223 6.079 6.698 8.493 8.558 8.431 3.47 0.0302375 nucleoporin 62kDa SCIN 2.087 1.966 1.5 3.762 3.859 3.297 3.473 0.001657 scinderin CCL17 2.118 0.862 2.202 3.684 3.998 3.309 3.474 0.0045189 chemokine (C-C motif) ligand 17 GCNT1 4.594 5.602 4.934 6.732 6.771 6.547 3.477 0.0037705 glucosaminyl (N-acetyl) transferase 1. core 2 DHCR7 6.216 5.375 4.163 7.159 7.636 7.175 3.483 0.0063426 7-dehydrocholesterol reductase DOHH 6.326 5.404 4.912 8.173 5.944 7.205 3.485 0.0397059 deoxyhypusine hydroxylase/monooxygenase LOC285696 2.795 1.951 2.634 4.378 4.244 4.597 3.487 0.0013043 No description MRPL12 7.596 6.278 6.074 8.882 7.876 8.292 3.488 0.0124168 mitochondrial ribosomal protein L12 ZFP28 4.734 2.416 3.441 4.679 5.436 5.247 3.495 0.0302569 zinc finger protein 28 homolog (mouse) ACSBG2 0.924 1.03 1.164 3.074 2.835 2.708 3.496 0.0004786 acyl-CoA synthetase bubblegum family member 2 HIRA 8.011 6.824 6.847 8.921 8.829 8.63 3.496 0.0083101 HIR histone cell cycle regulation defective homolog A (S. cerevisiae) MTMR1 3.088 3.295 3.073 3.97 5.103 4.928 3.502 0.007629 myotubularin related protein 1 AKNAD1 1.896 1.228 1.47 3.038 3.946 3.128 3.505 0.0028268 AKNA domain containing 1 KLF16 10.58 8.675 8.898 10.708 10.789 10.626 3.508 0.0430214 Kruppel-like factor 16 DDX46 6.794 7.095 6.975 8.907 8.131 8.853 3.511 0.0025549 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 NUDC 10.024 8.815 8.844 11.163 10.662 10.629 3.516 0.0092652 nuclear distribution gene C homolog (A. nidulans) PCID2 3.823 5.238 3.71 5.634 5.64 5.658 3.523 0.0225334 PCI domain containing 2 DOK7 3.169 2.722 1.911 5.069 3.444 4.539 3.524 0.0134628 docking protein 7 LOC1001330 7.145 5.046 5.473 7.299 7.222 7.292 3.529 0.0415819 No description 91 ZNF69 1.037 0.96 1.287 3.106 2.493 3.108 3.532 0.0013114 zinc finger protein 69 G6PD 7.489 5.803 6.118 8.785 7.902 7.939 3.532 0.0131845 glucose-6-phosphate dehydrogenase MTND1 13.394 11.844 11.268 13.444 13.665 14.023 3.533 0.0284281 No description MIF4GD 5.038 3.677 3.559 5.61 5.584 5.383 3.54 0.018627 MIF4G domain containing RABEPK 7.178 5.402 5.229 7.391 7.053 7.582 3.54 0.0389576 Rab9 effector protein with kelch motifs LY6K 8.351 9.503 8.635 10.502 10.463 10.399 3.55 0.0050791 lymphocyte antigen 6 complex, locus K GLB1L2 5.107 4.342 4.198 6.641 6.032 6.171 3.553 0.0035823 galactosidase, beta 1-like 2 ANKS3 6.042 5.444 6.243 8.073 7.282 7.342 3.555 0.0046984 ankyrin repeat and sterile alpha motif domain containing 3 U2AF2 9.729 8.441 9.127 10.958 11.028 10.718 3.558 0.0038714 U2 small nuclear RNA auxiliary factor 2 DNAJC9 5.199 4.376 3.626 5.658 6.364 6.209 3.562 0.0102182 DnaJ (Hsp40) homolog, subfamily C, member 9 NFKBIL2 0.625 1.733 0.543 3.406 2.376 2.618 3.563 0.0063991 No description KBTBD7 1.709 1.342 1.747 2.171 3.623 3.543 3.565 0.0154862 kelch repeat and BTB (POZ) domain containing 7 C16orf67 4.428 5.225 5.824 7.269 6.98 7.061 3.568 0.0032246 No description CD82 2.612 3.77 2.419 4.808 4.258 4.475 3.577 0.0103928 CD82 molecule LOC1001287 0.708 0.552 0.886 2.391 2.548 3.108 3.579 0.0008807 No description 88 CD22 0.825 1.893 1.126 2.886 3.194 2.968 3.585 0.0034678 CD22 molecule RANBP1 8.727 6.9 7.71 9.97 9.235 9.553 3.587 0.0098734 RAN binding protein 1 PRSS21 4.527 5.398 3.043 7.472 4.886 6.092 3.59 0.044106 protease, serine, 21 (testisin) ZNF286A 1.492 1.366 0.543 2.388 3.581 2.548 3.592 0.0083351 zinc finger protein 286A AOYP1 4.208 2.588 2.41 4.503 4.419 4.435 3.598 0.0319346 acylphosphatase 1, erythrocyte (common) type SNRNP40 5.577 4.405 4.394 6.689 6.57 6.242 3.601 0.0058375 small nuclear ribonucleoprotein 40kDa (U5) SNORD10 4.393 2.934 3.689 5.546 5.357 5.821 3.622 0.0041082 small nucleolar RNA, C/D box 10 LETM2 3.392 3.23 3.178 5.25 4.733 5.153 3.624 0.0008736 leucine zipper-EF-hand containing transmembrane protein 2 IL11 6.137 5.087 4.875 6.796 7.052 6.946 3.626 0.0081677 interleukin 11 MAP1LC3C 1.719 −0.529 0.797 1.471 2.797 2.656 3.627 0.0329806 microtubule-associated protein 1 light chain 3 gamma PDCD2 6.157 4.941 5.137 7.242 7.021 6.802 3.633 0.0070659 programmed cell death 2 NGEF 1.714 −0.046 −0.104 1.818 3.341 1.779 3.641 0.0240402 neuronal guanine nucleotide exchange factor PRKAA2 3.89 3.954 3.296 5.819 5.199 5.409 3.642 0.0021721 protein kinase, AMP-activated, alpha 2 catalytic subunit TUBA1C 11.595 9.855 9.431 12.125 11.658 11.719 3.642 0.0308764 tubulin, alpha 1c PMS2L1 1.908 1.262 2.457 3.774 4.518 3.068 3.644 0.006628 No description PNLDC1 1.714 1.715 1.219 3.588 3.513 3.156 3.662 0.000938 poly(A)-specific ribonuclease (PARN)-like domain containing 1 ZGLP1 3.51 2.896 2.973 4.77 5.193 4.942 3.665 0.0011884 zinc finger, GATA-like protein 1 REXO4 7.631 5.467 5.697 8.192 7.34 7.635 3.665 0.0458289 REX4, RNA exonuclease 4 homolog (S. cerevisiae) H2AFX 10.094 8.448 7.599 9.855 10.323 10.333 3.667 0.0486113 H2A histone family, member X GPR97 3.026 2.544 1.368 4.902 3.755 4.256 3.669 0.0068885 G protein-coupled receptor 97 PGM5P2 3.234 3.568 2.767 5.17 5.11 5.009 3.671 0.0010446 phosphoglucomutase 5 pseudogene 2 ALG3 7.413 6.003 5.447 8.5 7.885 7.71 3.686 0.0154339 asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae) KRT16P2 1.571 1.736 1.033 2.735 5.665 3.454 3.689 0.0081355 keratin 16 pseudogene 2 EXOSC5 5.746 4.784 5.234 7.265 7.119 6.784 3.693 0.0024211 exosome component 5 DCST1 0.403 −0.887 1.847 1.743 2.39 2.288 3.694 0.0339608 DC-STAMP domain containing 1 PPP1R14C 3.74 5.541 5.134 7.164 6.387 7.019 3.695 0.0060285 protein phosphatase 1, regulatory (inhibitor) subunit 14C C11orf83 3.315 3.149 3.861 5.459 5.043 5.204 3.702 0.0016255 chromosome 11 open reading frame 83 RPL18 12.725 11.636 11.962 13.854 13.958 13.854 3.713 0.0028905 ribosomal protein L18 C11orf71 3.356 2.838 4.09 4.582 5.984 5.411 3.716 0.0069729 chromosome 11 open reading frame 71 PI4KAP1 3.248 4.049 3.596 4.032 5.974 5.49 3.717 0.0261265 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1 GPR35 4.684 4.194 3.902 6.148 6.089 6.018 3.719 0.0012914 G protein-coupled receptor 35 SLC19A1 4.663 3.654 3.778 5.96 5.678 5.671 3.732 0.0034321 solute carrier family 19 (folate transporter), member 1 LOC643763 3.475 2.504 2.616 4.511 4.674 4.517 3.733 0.0033405 No description GPR37L1 4.761 4.865 4.023 6.277 6.767 6.491 3.737 0.0014839 G protein-coupled receptor 37 like 1 STK35 5.723 5.263 6.335 6.935 8.237 7.686 3.737 0.0059684 serine/threonine kinase 35 ISG20L2 9.643 7.905 7.545 9.832 9.707 9.808 3.741 0.0385905 interferon stimulated exonuclease gene 20kDa-like 2 HCG4 2.84 2.039 1.66 2.489 4.745 4.037 3.745 0.0361408 HLA complex group 4 C12orf65 5.478 4.639 4.419 6.364 6.863 6.546 3.751 0.003812 chromosome 12 open reading frame 65 KCNK3 2.637 4.659 3.125 5.032 5.483 4.639 3.753 0.0258582 potassium channel, subfamily K, member 3 SLC12A3 −0.012 1.604 0.422 2.293 2.332 2.735 3.759 0.0076361 solute carrier family 12 (sodium/chloride transporters), member 3 POU2F2 5.042 4.443 3.679 6.357 6.813 6.294 3.77 0.0022609 POU class 2 homeobox 2 UNC93B1 5.124 2.988 3.784 6.003 5.69 5.702 3.78 0.011994 unc-93 homolog B1 (C. elegans) MGAT5B 0.838 0.834 1.277 3.212 2.758 2.04 3.782 0.0048716 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N- acetyl-glucosaminyltransferase, isozyme B TNFRSF10A 2.847 2.807 2.021 5.087 3.74 4.729 3.789 0.0044344 tumor necrosis factor receptor superfamily, member 10a LYSMD2 6.494 4.261 4.611 7.082 6.394 6.532 3.789 0.0355319 LysM, putative peptidoglycan-binding, domain containing 2 KIAA1826 4.497 2.629 3.067 5.463 4.857 4.989 3.79 0.0144323 KIAA1826 MRPL53 3.474 1.604 2.792 4.894 4.596 4.715 3.791 0.0043765 mitochondrial ribosomal protein L53 BIRC5 2.493 1.298 1.896 3.464 3.822 3.835 3.8 0.0034464 baculoviral lAP repeat-containing 5 ABCC3 4.901 5.814 5.323 7.779 6.438 7.255 3.815 0.0059898 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 GPR109A −0.648 1.219 −0.904 1.029 2.938 2.288 3.817 0.0134235 G protein-coupled receptor 109A ACCN4 0.589 0.323 0.251 1.623 2.623 2.258 3.824 0.0025478 amiloride-sensitive cation channel 4, pituitary HSD17B10 7.995 6.601 6.274 8.618 8.537 8.426 3.828 0.015831 hydroxysteroid (17-beta) dehydrogenase 10 SOLH 8.845 6.976 7.355 9.912 9.18 9.293 3.83 0.0145339 small optic lobes homolog (Drosophila) DNASE1L2 1.44 −1.775 0.599 1.898 2.539 2.556 3.837 0.0174837 deoxyribonuclease l-like 2 GLB1L3 1.433 1.988 2.884 3.861 4.149 3.929 3.838 0.0041368 galactosidase, beta 1-like 3 MRPS30 6.457 4.515 4.626 6.712 6.538 6.572 3.852 0.0375267 mitochondrial ribosomal protein S30 RPS16 11.739 10.233 10.578 13.149 12.523 12.396 3.853 0.0068212 ribosomal protein S16 SBSN 1.742 1.199 2.215 3.679 4.085 3.689 3.856 0.0011741 suprabasin SERPINA1 6.131 5.128 5.249 7.076 7.534 7.465 3.858 0.0026579 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 AREG 5.088 6.893 5.023 7.495 6.97 7.351 3.858 0.0219446 amphiregulin CLDN1 2.834 3.832 3.834 4.285 6.41 5.784 3.868 0.0115246 claudin 1 PYGM 4.844 4.582 4.697 7.172 6.565 6.535 3.871 0.0005652 phosphorylase, glycogen, muscle SSU72 9.825 8.412 8.52 10.823 10.371 10.475 3.877 0.0098877 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) DCAF4 7.238 5.311 5.473 7.728 7.266 7.454 3.878 0.0309845 DDB1 and CUL4 associated factor 4 ADNP2 6.358 6.032 5.364 7.525 8.082 7.989 3.882 0.0019561 ADNP homeobox2 QRICH2 6.097 4.13 5.304 7.47 7.261 6.655 3.882 0.008685 glutamine rich 2 WRAP53 5.651 3.397 3.91 6.196 5.867 5.817 3.882 0.0250261 WD repeat containing, antisense to TP53 C9orf152 2.315 2.797 1.993 4.214 4.274 4.285 3.887 0.0010589 chromosome 9 open reading frame 152 ASB16 2.994 2.14 2.677 4.636 4.437 4.668 3.889 0.0010024 ankyrin repeat and SOCS box-containing 16 CCBP2 5.932 5.086 6.822 8.141 7.892 7.668 3.891 0.0053137 chemokine binding protein 2 FERMT3 5.215 4.32 4.796 6.164 7.176 6.846 3.892 0.0027409 fermitin family member 3 SLC22A9 0.162 0.464 0.17 2.396 2.427 1.715 3.898 0.0011598 solute carrier family 22 (organic anion transporter), member 9 CNTD2 4.824 4.719 5.307 6.79 7.32 6.641 3.907 0.0011812 cyclin N-terminal domain containing 2 TRMT6 6.404 5.306 4.952 8.254 6.919 7.818 3.909 0.005107 tRNA methyltransferase 6 homolog (S. cerevisiae) JAGN1 6.92 5.027 5.058 7.502 6.994 7.059 3.909 0.0292395 jagunal homolog 1 (Drosophila) CSF3R 1.818 1.386 0.251 3.489 2.221 3.52 3.918 0.0097918 colony stimulating factor 3 receptor (granulocyte) SLC39A4 4.873 3.851 3.431 6.594 5.403 5.84 3.925 0.0072076 solute carrier family 39 (zinc transporter), member 4 VPS11 7.112 5.413 5.489 7.733 7.465 7.449 3.934 0.0193074 vacuolar protein sorting 11 homolog (S. cerevisiae) MRPS15 6.838 4.964 5.532 7.958 7.257 7.512 3.945 0.0112256 mitochondrial ribosomal protein S15 SPDYA 0.208 1.847 0.886 2.63 3.373 2.872 3.96 0.005127 speedy homolog A (Xenopus laevis) SNTA1 4.969 2.549 3.126 5.198 5.115 5.044 3.968 0.0342205 syntrophin, alpha 1 (dystrophin-associated protein A1,59kDa, acidic component) NOG 7.095 5.447 6.201 8.276 7.829 8.191 3.97 0.0061286 noggin C19orf25 5.676 3.841 4.146 6.856 6.137 6.115 3.975 0.0119081 chromosome 19 open reading frame 25 C11orf84 6.608 4.821 4.788 7.546 8.054 6.782 3.982 0.0097453 chromosome 11 open reading frame 84 C15orf48 2.429 2.004 1.826 4.408 3.998 3.918 3.985 0.0007012 chromosome 15 open reading frame 48 SGSM1 3.331 3.371 2.42 5.355 5.261 5.326 3.986 0.0006582 small G protein signaling modulator 1 LOC1002868 2.32 1.908 2.025 3.953 4.158 4.02 3.988 0.0003713 No description 44 MRPL41 7.476 5.877 6.41 9.157 8.406 8.345 3.989 0.0046283 mitochondrial ribosomal protein L41 S100A9 4.281 2.419 3.707 5.66 6.28 5.626 3.998 0.0029076 S100 calcium binding protein A9 CCK 2.546 2.257 2.339 5.05 4.14 4.339 4.001 0.0008085 cholecystokinin HDX 4.167 1.885 2.549 4.757 4.553 4.28 4.01 0.023465 highly divergent homeobox COMTD1 3.303 2.964 3.133 5.766 4.969 5.059 4.014 0.000694 catechol-O-methyltransferase domain containing 1 MARCKSL1 10.077 8.475 8.657 10.571 10.772 10.662 4.015 0.0132761 MARCKS-like 1 GAL 5.185 4.456 4.141 6.798 6.34 6.465 4.025 0.0019918 galanin prepropeptide NCAPD3 3.576 2.6 3.032 5.588 4.998 4.9 4.035 0.001554 non-SMC condensin II complex, subunit D3 FBXL6 6.755 5.424 6.114 8.033 8.334 8.127 4.035 0.0020491 F-box and leucine-rich repeat protein 6 LOC728323 1.037 2.497 0.162 2.638 3.051 3.498 4.038 0.0177205 No description GNL1 6.507 5.059 5.067 7.541 7.712 7.074 4.04 0.0060571 guanine nucleotide binding protein-like 1 PHLDB3 6.691 5.051 4.978 7.126 7.065 6.997 4.04 0.022444 pleckstrin homology-like domain, family B, member 3 FAHD1 4.917 3.63 2.534 6.503 4.549 6.026 4.042 0.0222587 fumarylacetoacetate hydrolase domain containing 1 TKT 8.956 7.873 7.22 10.453 9.851 9.893 4.056 0.0047185 transketolase AKT1S1 6.428 4.691 5.328 7.351 7.734 7.028 4.063 0.0071332 AKT1 substrate 1 (proline-rich) RNMTL1 7.241 3.99 5.136 7.454 7.158 7.115 4.063 0.0412492 RNA methyltransferase like 1 BAD 7.439 5.076 6.06 8.087 8.113 7.897 4.078 0.0152128 BCL2-associated agonist of cell death PITPNM1 7.127 7.181 6.69 8.722 9.464 9.044 4.09 0.0007655 phosphatidylinositol transfer protein, membrane- associated 1 EXOSC6 6.658 5.634 5.641 7.723 7.83 7.668 4.094 0.0034535 exosome component 6 C1orf163 5.715 2.831 4.159 6.203 6.003 6.239 4.124 0.0215246 chromosome 1 open reading frame 163 LOC285847 1.228 1.075 2.453 1.825 4.498 3.614 4.125 0.0398784 No description L3MBTL2 5.923 4.104 4.799 7.161 6.65 6.848 4.138 0.0063705 I(3)mbt-like 2 (Drosophila) TRPM2 2.41 0.924 1.09 4.156 2.983 3.237 4.169 0.0069021 transient receptor potential cation channel, subfamily M, member 2 PCYT1A 1.703 0.666 1.778 4.426 1.88 3.763 4.171 0.0192273 phosphate cytidylyltransferase 1, choline, alpha COX7A2L 5.105 3.459 3.932 5.993 6.29 5.65 4.173 0.0078271 cytochrome c oxidase subunit VIIa polypeptide 2 like SCO1 6.066 4.076 4.901 7.833 6.702 6.964 4.178 0.0067089 SCO cytochrome oxidase deficient homolog 1 (yeast) TSG1 2.539 4.266 3.091 4.495 6.329 5.815 4.179 0.0074565 No description CCDC72 8.846 7.787 8.612 10.913 10.403 10.451 4.19 0.0012699 coiled-coil domain containing 72 CYP2B6 3.353 3.296 2.689 5.312 5.426 5.196 4.208 0.0004143 cytochrome P450, family 2, subfamily B, polypeptide 6 CHCHD2 10.609 8.887 10.041 12.625 12.115 11.859 4.21 0.0025191 coiled-coil-helix-coiled-coil-helix domain containing 2 KLC2 7.25 5.649 6.333 8.521 8.395 8.41 4.22 0.0034607 kinesin light chain 2 C19orf77 2.167 2.194 1.959 5.57 3.538 4.246 4.224 0.0033333 chromosome 19 open reading frame 77 PABPC4 10.428 8.035 8.997 11.128 10.683 11.082 4.242 0.0175581 poly(A) binding protein, cytoplasmic 4 (inducible form) CST9 −0.904 0.814 0.315 2.548 2.06 2.4 4.244 0.0027767 cystatin 9 (testatin) STEAP3 4.036 2.506 3.004 5.019 5.092 5.17 4.25 0.0042513 STEAP family member 3 AP1S1 3.715 3.274 2.695 5.439 5.362 4.81 4.251 0.0020205 adaptor-related protein complex 1, sigma 1 subunit LGALS12 1.424 0.499 0.825 3.493 3.513 2.54 4.254 0.0015397 lectin, galactoside-binding, soluble, 12 EDARADD 4.623 2.742 2.232 5.19 4.852 4.325 4.265 0.0371439 EDAR-associated death domain ITGAM 0.625 0.588 1.234 3.581 2.569 2.721 4.274 0.0015969 integrin, alpha M (complement component 3 receptor 3 subunit) SUV39H1 3.56 1.562 1.234 4.405 3.331 3.936 4.277 0.0256901 suppressor of variegation 3-9 homolog 1 (Drosophila) C21orf99 1.161 −0.258 1.894 3.258 1.894 3.601 4.279 0.0173635 No description SCGB3A1 2.623 2.46 1.645 4.347 4.636 4.562 4.294 0.0006725 secretoglobin, family 3A, member 1 NLE1 6.503 4.705 5.127 7.712 7.101 7.229 4.295 0.0079109 notchless homolog 1 (Drosophila) RPS9 13.004 11.407 12.007 14.113 14.113 13.731 4.303 0.0057802 ribosomal protein S9 FST 10.28 9.041 7.553 11.635 10.617 11.147 4.306 0.0123667 follistatin CD3EAP 8.757 8.254 7.955 10.475 10.361 10.224 4.309 0.0007369 CD3e molecule, epsilon associated protein RASD2 2.776 3.267 2.145 5.368 4.575 4.886 4.317 0.0015111 RASD family, member 2 TUSC2 7.274 5.862 5.955 8.569 8.067 8.061 4.323 0.0055591 tumor suppressor candidate 2 PDZD9 2.118 2.152 1.942 4.428 3.869 4.231 4.326 0.0003427 PDZ domain containing 9 SNORD66 0.609 −0.887 0.224 2.056 2.725 2.099 4.335 0.0020985 small nucleolar RNA, C/D box 66 MFNG 6.578 5.117 4.912 7.03 7.537 7.414 4.342 0.0092581 MFNG O-fucosylpeptide 3-beta-N- acetylglucosaminyltransferase NFATC3 7.503 5.451 5.51 7.575 7.955 7.888 4.359 0.0235337 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 SNORA80B −0.192 −0.177 −1.775 0.673 1.948 1.908 4.362 0.0057874 small nucleolar RNA, H/ACA box 80B CDKN2A 3.997 2.388 3.88 5.967 6.122 5.616 4.364 0.0017815 cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) MAP7D2 2.175 1.471 2.078 4.16 4.3 3.785 4.365 0.0006096 MAP7 domain containing 2 TSEN34 3.369 2.423 2.93 4.542 5.495 5.087 4.365 0.0016785 tRNA splicing endonuclease 34 homolog (S. cerevisiae) C12orf61 2.359 0.499 1.219 4 3.56 2.628 4.373 0.0089991 chromosome 12 open reading frame 61 PPP1R16A 4.051 4.065 3.764 5.896 6.297 5.99 4.383 0.0002797 protein phosphatase 1, regulatory (inhibitor) subunit 16A SCARNA13 −0.192 2.17 2.834 3.906 4.327 4.305 4.393 0.0076147 small Cajal body-specific RNA 13 MYO1G 3.86 2.784 4.142 5.997 5.895 6.229 4.397 0.0009809 myosin IG KRTCAP3 2.592 2.004 0.315 4.199 4.14 3.634 4.397 0.0050304 keratinocyte associated protein 3 CYP4F11 7.316 6.229 6.585 9.746 7.39 8.723 4.402 0.0163783 cytochrome P450. family 4. subfamily F. polypeptide 11 KRT18 3.256 2.112 1.573 3.932 5.303 4.253 4.41 0.0055999 keratin 18 COQ3 2.556 2.657 2.363 5.213 4.253 4.698 4.412 0.0006868 coenzyme Q3 homolog, methyltransferase (S. cerevisiae) CSNK2A1P 7.227 5.222 5.672 8.089 7.816 7.647 4.419 0.01217 casein kinase 2, alpha 1 polypeptide pseudogene OXT 2.908 −0.887 2.111 3.841 4.397 4.256 4.423 0.0112184 oxytocin, prepropeptide NCF4 3.988 1.547 2.976 5.085 5.688 5.121 4.424 0.0046026 neutrophil cytosolic factor 4, 40kDa COX6B2 2.447 1.677 2.028 4.056 4.598 4.149 4.441 0.0005781 cytochrome c oxidase subunit VIb polypeptide 2 (testis) RRP9 9.54 6.49 8.062 10.874 10.216 10.006 4.448 0.0117142 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) AUP1 6.266 5.966 6.725 8.15 8.865 8.422 4.458 0.0008664 ancient ubiquitous protein 1 COLEC11 4.775 2.89 3.418 4.508 6.936 6.059 4.474 0.0166681 collectin sub-family member 11 GPR25 0.888 −0.887 −0.064 1.898 2.142 2.099 4.481 0.0040431 G protein-coupled receptor 25 CDH16 1.03 0.903 0.978 2.064 3.462 3.147 4.496 0.0036324 cadherin 16, KSP-cadherin PCNA 7.72 6.162 6.606 8.776 8.786 8.716 4.499 0.0043128 proliferating cell nuclear antigen KRT16 11.189 11.579 9.689 11.894 13.756 12.909 4.522 0.0140674 keratin 16 TXNIP 7.046 6.237 8.025 8.677 9.629 9.223 4.523 0.0054633 thioredoxin interacting protein LMAN2L 5.638 3.781 3.603 6.154 6.42 5.782 4.529 0.0167597 lectin, mannose-binding 2-like TUBA4A 4.511 2.57 2.981 5.165 5.881 5.056 4.542 0.0082901 tubulin, alpha 4a MRPL13 5.845 3.919 4.544 7.341 6.388 6.731 4.552 0.0071017 mitochondrial ribosomal protein L13 LRRC56 5.059 3.43 3.807 6.085 6.319 5.621 4.565 0.0063919 leucine rich repeat containing 56 ARRB2 4.349 4.09 4.386 6.283 6.742 6.415 4.573 0.0002583 arrestin, beta 2 RPRM 1.719 2.593 −0.274 4.001 3.915 3.874 4.583 0.0056071 reprimo, TP53 dependent G2 arrest mediator candidate C19orf55 3.046 2.316 2.119 4.52 4.317 4.534 4.588 0.0013429 chromosome 19 open reading frame 55 ZC3H13 5.441 6.072 4.754 7.761 7.213 7.645 4.607 0.0020562 zinc finger CCCH-type containing 13 ERP27 2.683 0.862 0.315 2.886 3.832 3.068 4.613 0.0152415 endoplasmic reticulum protein 27 LAT2 4.198 2.639 2.709 4.901 4.917 5.077 4.622 0.007981 linker for activation of T cells family, member 2 KCNN4 7.941 5.941 5.76 8.168 8.155 7.994 4.64 0.0317858 potassium intermediate/small conductance calcium- activated channel, subfamily N, member 4 NKX3-1 6.227 4.673 4.038 6.772 6.892 7.04 4.656 0.0107849 NK3 homeobox 1 AURKAIP1 7.984 6.061 6.611 9.458 8.832 8.672 4.661 0.005997 aurora kinase A interacting protein 1 SH2D2A 0.162 0.464 0.888 2.157 3.111 2.813 4.67 0.0011383 SH2 domain containing 2A HOMER2 4.035 2.588 2.783 5.379 5.007 4.917 4.673 0.0041819 homer homolog 2 (Drosophila) C17orf56 2.952 2.605 1.473 4.543 5.183 4.613 4.694 0.0015755 chromosome 17 open reading frame 56 CPNE7 1.949 1.709 2.205 4.193 4.571 3.662 4.739 0.0007584 copine VII TMEM97 6.486 4.346 4.282 6.904 6.597 6.529 4.745 0.0291572 transmembrane protein 97 ACTR5 6.194 5.235 4.79 7.646 7.483 7.189 4.749 0.0029148 ARP5 actin-related protein 5 homolog (yeast) S100A6 11.768 9.001 10.197 13.263 12.445 12.265 4.749 0.0095071 S100 calcium binding protein A6 GJB3 1.077 0.323 0.68 3.874 2.928 2.459 4.751 0.0015325 gap junction protein, beta 3, 31 kDa RASL10B 3.642 1.15 0.884 4.677 3.134 3.443 4.757 0.0391007 RAS-like, family 10, member B POPDC3 0.723 0.992 −0.104 3.246 2.332 2.261 4.77 0.0030057 popeye domain containing 3 KRT13 −0.376 1.828 −0.778 1.672 2.317 1.878 4.77 0.032112 keratin 13 TMEM199 4.989 3.24 3.662 6.335 5.917 5.832 4.772 0.0047256 transmembrane protein 199 NKAPL −0.012 0.78 −0.104 2.417 2.548 2.153 4.779 0.000895 NFKB activating protein-like FAM83G 4.144 3.539 2.735 5.797 5.966 5.521 4.785 0.0015254 family with sequence similarity 83, member G SPI1 1.62 0.162 2.401 4.463 3.294 3.879 4.787 0.0044831 spleen focus forming virus (SFFV) proviral integration oncogene spH KRT19 4.436 4.34 4.104 6.089 7.521 6.602 4.796 0.0010231 keratin 19 PMEPA1 9.046 7.127 7.526 10.578 9.787 9.791 4.806 0.0058582 prostate transmembrane protein, androgen induced 1 ZNF98 2.132 1.783 2.111 4.121 4.397 4.109 4.807 0.0002368 zinc finger protein 98 FOXL1 2.031 1.432 1.342 3.612 4.204 3.743 4.823 0.0005294 forkhead box L1 SNORD19 3.073 2.526 2.986 5.259 4.875 5.324 4.832 0.0003141 small nucleolar RNA, C/D box 19 MT2A 13.756 13.204 14.736 16.031 15.551 16.031 4.84 0.0041296 metallothionein 2A TFR2 1.379 0.224 1.724 3.66 3.657 3.541 4.851 0.0010303 transferrin receptor 2 E2F4 5.133 3.458 3.76 6.371 6.172 5.737 4.854 0.005758 E2F transcription factor 4, p107/p130-binding ANKRD1 4.076 4.809 6.863 7.681 6.355 7.332 4.855 0.0309401 ankyrin repeat domain 1 (cardiac muscle) AATF 7.494 5.434 5.546 8.204 7.761 7.838 4.897 0.0171532 apoptosis antagonizing transcription factor RNASE6 1.571 −0.258 0.589 2.735 2.994 2.889 4.927 0.0030658 ribonuclease, RNase A family, k6 B3GAT1 2.628 4.114 2.69 5.857 4.93 5.58 4.931 0.0029363 beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) HIST1H1C 1.44 1.033 2.392 3.395 5.173 3.336 4.935 0.0055305 histone cluster 1, H1c POMZP3 3.517 0.391 1.148 3.451 2.938 4.256 4.935 0.0411533 POM121 and ZP3 fusion ADCK2 6.498 3.642 4.42 6.73 6.903 6.485 4.961 0.0267511 aarF domain containing kinase 2 UHRF2 4.149 4.375 5.346 6.1 7.659 7.461 4.97 0.0027696 ubiquitin-like with PHD and ring finger domains 2 HMGA2 4.978 4.598 5.928 8.258 5.952 7.292 4.971 0.0146033 high mobility group AT-hook 2 NPB 1.44 −1.775 0.224 2.652 2.539 0.831 4.974 0.0360142 neuropeptide B RPL7L1 2.4 2.521 1.33 4.838 3.922 3.924 4.983 0.0029706 ribosomal protein L7-like 1 LRRC69 1.091 −0.258 −0.274 2.048 2.46 2.208 5.002 0.0032976 leucine rich repeat containing 69 MICALCL 4.864 6.268 4.689 8.592 5.685 7.48 5.007 0.0294419 MICAL C-terminal like TMEM52 3.322 0.162 1.747 4.266 4.072 3.444 5.011 0.0172905 transmembrane protein 52 SLC7A5 11.505 9.988 9.514 13.092 12.191 12.316 5.019 0.0058231 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 HMHA1 3.661 1.944 3.452 5.998 5.292 4.931 5.052 0.0034192 histocompatibility (minor) HA-1 FKBP5 6.359 4.534 7.267 8.791 8.64 8.697 5.054 0.0042305 FK506 binding protein 5 DLST 5.486 5.479 7.178 7.82 8.321 8.344 5.067 0.0051198 dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) SFRS7 7.95 6.614 6.878 9.221 9.351 9.008 5.071 0.0024862 No description PGAM5 1.297 0.623 −0.274 3.645 3.229 1.265 5.089 0.0138807 phosphoglycerate mutase family member 5 MRPS18C 5.03 2.607 4.016 6.642 6.369 6.122 5.108 0.0040359 mitochondrial ribosomal protein S18C LRFN4 6.903 4.772 5.125 8.13 7.485 7.245 5.132 0.0107162 leucine rich repeat and fibronectin type III domain containing 4 FCRLB 0.609 1.033 1.148 3.279 3.517 3.119 5.165 0.000244 Fc receptor-like B S100A3 2.798 0.623 −0.648 3.744 2.994 1.878 5.171 0.0472848 S100 calcium binding protein A3 PHKG1 2.111 2.877 1.809 4.44 4.784 4.495 5.22 0.0007155 phosphorylase kinase, gamma 1 (muscle) UBE2M 4.586 3.783 3.619 6.005 6.817 6.31 5.224 0.0008593 ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) PSD4 4.159 3.091 3.773 6.547 5.925 5.856 5.233 0.0007226 pleckstrin and Sec7 domain containing 4 KIAA0406 4.741 2.649 3.163 5.552 5.689 5.358 5.237 0.0079595 No description TMED10 2.946 3.692 2.716 5.108 5.851 5.779 5.251 0.0006654 transmembrane emp24-like trafficking protein 10 (yeast) LOC645851 0.162 0.323 0.68 2.72 2.053 3.125 5.268 0.0009451 No description RASGEF1A 1.219 1.46 1.271 3.865 3.764 3.022 5.294 0.0005366 RasGEF domain family, member 1A UHRF1 2.7 1.911 1.575 4.021 4.565 4.33 5.348 0.001109 ubiquitin-like with PHD and ring finger domains 1 SPAG4 −0.648 0.251 0.599 2.437 3.025 2.651 5.373 0.0005438 sperm associated antigen 4 HESRG 5.267 4.245 4.07 6.682 6.59 7.053 5.413 0.0013501 No description FOXC2 1.82 1.651 0.817 4.262 4.037 3.774 5.434 0.0004071 forkhead box C2 (MFH-1, mesenchyme forkhead 1) TLR2 3.159 2.968 2.549 4.696 6.253 5.425 5.491 0.0010875 toll-like receptor 2 GNL2 7.876 5.882 6.454 8.967 8.687 8.912 5.495 0.0052415 guanine nucleotide binding protein-like 2 (nucleolar) BANP 7.132 4.889 5.115 7.388 7.857 7.576 5.507 0.0154067 BTG3 associated nuclear protein SPEM1 2.118 −0.529 0.315 2.776 2.797 2.208 5.507 0.0174766 spermatid maturation 1 ACOT7 8.143 6.403 6.119 8.935 8.869 8.629 5.527 0.0100572 acyl-CoA thioesterase 7 TMEM177 3.081 1.651 1.99 4.463 4.478 4.383 5.553 0.0018387 transmembrane protein 177 C20orf165 0.525 0.162 0.162 2.638 2.999 2.008 5.555 0.0006797 chromosome 20 open reading frame 165 UBIAD1 9.212 5.604 6.88 9.47 9.312 9.367 5.604 0.0256972 UbiA prenyltransferase domain containing 1 BLOC1S3 6.369 3.35 3.695 6.736 6.13 6.194 5.651 0.0350311 biogenesis of lysosomal organelles complex-1, subunit 3 RPL26L1 6.58 4.996 4.165 7.503 7.516 7.199 5.686 0.0080196 ribosomal protein L26-like 1 PSPN 4.022 2.257 1.315 5.302 4.347 4.766 5.69 0.0101152 persephin IMP4 3.308 3.291 2.847 5.702 5.544 5.819 5.699 0.000171 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) XDH 4.776 5.707 3.555 7.592 6.39 7.288 5.704 0.0047471 xanthine dehydrogenase NEFM 6.452 7.098 6.474 8.983 9.556 9.29 5.778 0.0002511 neurofilament, medium polypeptide ZSCAN29 5.93 4.207 4.316 6.741 6.885 6.967 5.79 0.0052064 zinc finger and SCAN domain containing 29 C19orf38 2.289 0.623 −0.648 2.548 3.194 3.172 5.853 0.0129234 chromosome 19 open reading frame 38 HUS1B 2.073 0.224 0.842 3.684 2.797 3.394 5.862 0.0040939 HUS1 checkpoint homolog b (S. pombe) FGFBP1 0.786 1.199 0.17 2.724 3.806 3.29 5.873 0.0007727 fibroblast growth factor binding protein 1 TCTEX1D4 0.224 −0.529 −0.778 1.88 2.06 2.031 5.896 0.0005008 Tctexl domain containing 4 RAMP1 4.009 1.675 4.06 6.025 6.627 5.981 5.924 0.0025005 receptor (G protein-coupled) activity modifying protein 1 SRCRB4D 2.211 0.522 −0.778 4.076 3.093 3.068 5.939 0.0054275 scavenger receptor cysteine rich domain containing, group B (4 domains) FAM195A 5.781 3.888 4.405 7.572 6.877 6.98 5.959 0.0026651 family with sequence similarity 195, member A GJB5 3.546 1.126 1.079 4.329 3.661 4.037 5.99 0.0147764 gap junction protein, beta 5, 31.1kDa SCAF1 4.924 3.826 3.823 6.034 7.509 6.892 6.001 0.0015826 SR-related CTD-associated factor 1 SIRT7 6.055 5.188 4.939 8.103 7.81 7.733 6.157 0.0005223 sirtuin 7 TPST2 7.187 5.353 5.226 8.704 8.232 7.853 6.177 0.0046426 tyrosylprotein sulfotransferase 2 TIGD3 2.359 0.886 0.162 2.957 4.213 3.514 6.182 0.0050376 tigger transposable element derived 3 IL19 1.885 1.625 1.947 5.344 4.537 3.893 6.283 0.0004858 interleukin 19 TDRD10 −0.904 −0.258 0.315 2.97 −0.104 2.4 6.3 0.0278908 tudor domain containing 10 TGFB2 5.857 7.839 6.069 8.805 8.523 8.833 6.346 0.0060356 transforming growth factor, beta 2 ZNF48 4.656 2.091 1.042 5.757 4.759 4.453 6.355 0.0205273 zinc finger protein 48 MPZL3 1.703 1.982 0.757 3.855 4.652 3.821 6.363 0.0007799 myelin protein zero-like 3 TNFRSF18 5.884 3.456 3.229 6.608 6.179 5.915 6.434 0.0183723 tumor necrosis factor receptor superfamily, member 18 ASCL2 1.091 −0.529 −0.274 3.59 3.485 2.159 6.446 0.001393 achaete-scute complex homolog 2 (Drosophila) NOL7 3.498 2.647 3.727 6.419 5.706 5.559 6.464 0.0006511 nucleolar protein 7, 27kDa GAST 2.149 −0.258 1.196 3.949 3.258 3.902 6.527 0.0031688 gastrin LLGL2 5.229 4.307 3.785 7.072 6.962 7.013 6.528 0.0007083 lethal giant larvae homolog 2 (Drosophila) C12orf52 3.365 1.54 1.273 4.796 4.27 4.212 6.635 0.0044974 chromosome 12 open reading frame 52 KRTDAP 4.639 2.542 3.112 5.858 5.858 5.907 6.711 0.0030951 keratinocyte differentiation-associated protein IFNA2 −0.264 0.162 −0.21 3.272 1.387 2.54 6.725 0.0019489 interferon, alpha 2 CXCL5 2.812 0.283 3.082 5.567 5.058 5.689 6.747 0.0018817 chemokine (C-X-C motif) ligand 5 CCDC11 0.323 1.301 1.199 3.818 4.062 3.886 6.779 0.0001925 coiled-coil domain containing 11 CTRL 5.44 3.159 3.435 6.782 6.26 5.954 6.943 0.0066731 chymotrypsin-like SCGB1D2 −1.775 1.783 −1.775 1.029 2.725 2.819 6.982 0.017043 secretoglobin. family 1D. member 2 VNN1 0.162 1.685 0.585 3.041 3.389 3.457 6.983 0.0012342 vanin 1 PEX11B 5.092 2.76 3.348 5.833 6.435 6.159 7.018 0.0048115 peroxisomal biogenesis factor 11 beta PIK3R5 −1.155 −1.775 −0.376 2.437 −0.648 1.908 7.027 0.0169307 phosphoinositide-3-kinase, regulatory subunit 5 NPW 5.041 2.838 2.931 6.414 5.657 5.75 7.056 0.0064499 neuropeptide W ZNF628 4.382 2.41 2.883 5.707 5.722 5.337 7.079 0.0033047 zinc finger protein 628 RPL29 6.492 6.685 6.762 8.103 10.009 9.51 7.084 0.0018244 ribosomal protein L29 SLC25A38 6.205 3.999 4.209 7.411 6.912 7.058 7.208 0.0056285 solute carrier family 25, member 38 SLC34A2 1.916 1.305 1.818 3.748 5.428 4.677 7.253 0.0005953 solute carrier family 34 (sodium phosphate), member 2 RPS19BP1 5.607 4.22 4.064 7.776 7.444 7.036 7.849 0.0009094 ribosomal protein S19 binding protein 1 NOP16 5.385 3.98 4.13 7.004 7.367 7.353 8.131 0.0006239 NOP16 nucleolar protein homolog (yeast) CRB3 3.672 3.166 1.959 6.701 5.891 5.532 8.163 0.0007298 crumbs homolog 3 (Drosophila) DES 2.687 0.814 0.924 4.693 3.852 4.584 8.214 0.0014696 desmin C9orf140 3.738 1.801 1.44 5.159 4.859 4.697 8.323 0.0036252 chromosome 9 open reading frame 140 SCFD2 2.68 2.189 2.795 5.841 5.609 5.758 8.445 0.0001037 sed family domain containing 2 SLPI 3.645 1.547 0.162 4.018 5.164 4.648 8.579 0.0077234 secretory leukocyte peptidase inhibitor C2orf82 0.403 0.607 1.715 3.511 4.355 4.186 8.62 0.0003642 chromosome 2 open reading frame 82 PAX4 −0.104 −0.258 −0.012 3.045 3.247 2.73 8.868 0.0000894 paired box4 C4orf40 −0.904 −0.529 0.16 2.048 2.987 3.309 8.871 0.0003284 chromosome 4 open reading frame 40 SRL 3.686 1.228 1.674 5.842 4.874 4.763 9.188 0.0026923 sarcalumenin GOLGA6L1 −0.648 −0.177 2.241 2.901 3.025 3.412 9.202 0.0062982 golgin A6 family-like 1 MIR886 2.132 2.102 0.224 3.948 5.195 5.342 9.251 0.0010947 No description CTSL2 4.54 4.616 4.838 5.317 8.233 7.837 9.321 0.0091057 cathepsin L2 PHLDA2 8.598 7.122 6.049 10.47 10.352 10.321 9.382 0.0014002 pleckstrin homology-like domain, family A, member 2 KISS1 −0.192 −0.887 −1.775 3.081 2.142 1.908 9.666 0.0004286 KiSS-1 metastasis-suppressor MMP7 0.625 4.235 1.618 3.941 5.521 5.246 9.957 0.0124483 matrix metallopeptidase 7 (matrilysin, uterine) SAA4 1.275 0.886 2.817 4.593 5.075 4.474 9.975 0.0008521 serum amyloid A4, constitutive HIST1H4L 3.248 0.251 1.247 3.644 5.016 4.675 10.505 0.0053209 histone cluster 1. H4I GABRP 1.763 1.762 2.073 3.791 5.876 5.188 10.738 0.0008013 gamma-aminobutyric acid (GABA) A receptor, pi SERPINC1 2.495 −0.046 0.422 3.379 4.542 3.904 10.743 0.0028654 serpin peptidase inhibitor, clade C (antithrombin), member 1 OLFM4 1.388 2.061 1.483 3.182 5.508 5.288 10.906 0.0019418 olfactomedin 4 PINX1 2.398 3.094 2.348 6.625 5.779 6.329 11.557 0.0001252 PIN2/TERF1 interacting, telomerase inhibitor 1 PITX1 1.386 1.72 1.602 5.299 5.148 4.505 11.68 0.0001109 paired-like homeodomain 1 EFNA2 1.341 −1.775 −0.904 2.704 2.142 2.651 11.753 0.0042856 ephrin-A2 CCL20 1.714 2.455 3.84 6.084 6.09 6.143 12.42 0.0004429 chemokine (C-C motif) ligand 20 ST20 2.945 −0.177 1.148 4.824 4.999 4.713 12.783 0.0015039 suppressor of tumorigenicity 20 DEFB1 −1.775 −1.775 −0.904 2.437 1.527 2.819 13.204 0.0001782 defensin, beta 1 SAA1 10.069 7.303 10.989 13.808 13.834 13.704 13.351 0.0009952 serum amyloid A1 WFDC2 6.61 4.66 5.087 9.038 8.968 8.517 14.491 0.0004643 WAP four-disulfide core domain 2 HPDL 3.114 −0.887 1.494 5.908 5.566 5.088 16.818 0.0014424 4-hydroxyphenylpyruvate dioxygenase-like BCL11B 1.806 2.141 1.879 3.619 6.354 5.988 17.253 0.0016112 B-cell OLL/lymphoma 11B (zinc finger protein) IQCF1 −0.648 0.251 −1.493 3.204 4.397 3.336 17.708 0.0001853 IQ motif containing F1 C21orf121 −1.775 −1.775 2.834 4.198 2.39 4.155 17.937 0.008607 chromosome 21 open reading frame 121 EPR1 4.224 2.102 −1.775 6.277 6.395 5.49 18.057 0.0049846 effector cell peptidase receptor 1 (non-protein coding) PI3 1.275 1.044 1.219 5.305 6.038 5.364 19.165 0.0000751 peptidase inhibitor 3, skin-derived LTF 1.939 2.431 1.342 4.314 7.062 6.408 22.146 0.0006167 lactotransferrin SAA2 4.018 2.008 3.561 6.978 8.546 7.98 23.067 0.0002096 serum amyloid A2 HIST1H2BK 1.874 1.959 0.978 5.718 7.257 6.486 26.716 0.0000966 histone cluster 1, H2bk IGLL1 −0.904 −0.258 −0.274 −0.311 5.475 4.623 29.796 0.0136481 immunoglobulin lambda-like polypeptide 1 GSTT1 0.68 0.834 5.638 6.459 5.979 6.367 39.354 0.0077163 glutathione S-transferase theta 1 ESR2 −0.264 −0.046 4.539 6.365 5.571 8.985 57.055 0.002248 estrogen receptor 2 (ER beta) RBP4 2.439 −1.775 −0.904 4.939 5.016 4.562 57.368 0.0009165 retinol binding protein 4, plasma KRTAP2-4 4.991 2.17 3.451 9.151 10.712 10 93.615 0.0001181 keratin associated protein 2-4

TABLE 7 Differentially Exprssed Genes in Stromal Breast Epithelial Cells Nulliparous Parous (NP) Samples (P) Samples Pseudo Gene Stroma Stroma Stroma Stroma Stroma Stroma fold Symbol N33 N35 N58 N37 N39 N40 change P value Gene description Higher Expression in Nulliparous CIB1 8.918 0.751 7.453 0.751 0.751 0.751 −104.129 0.0263699 calcium and integrin binding 1 (calmyrin) RELL2 4.528 4.664 4.128 3.848 −0.834 −0.834 −31.160 0.0174792 RELT-like 2 COL1A1 13.613 10.721 10.752 5.932 7.368 6.175 −27.644 0.0005223 collagen, type I, alpha 1 CACNA1D 6.820 7.844 6.850 2.166 2.166 6.722 −25.177 0.0223877 calcium channel, voltage- dependent, L type, alpha 1D subunit FAM43B 6.144 6.144 4.173 1.588 0.951 0.166 −23.522 0.0002856 family with sequence similarity 43, member B C15orf48 5.915 6.941 4.306 5.421 0.166 0.166 −17.626 0.0311312 chromosome 15 open reading frame 48 WFIKKN1 4.894 4.917 4.820 4.226 0.751 0.751 −16.783 0.0171827 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 PI16 10.217 10.615 11.238 6.113 7.173 6.622 −16.742 0.0001532 peptidase inhibitor 16 FREM1 8.554 5.952 6.788 2.488 4.581 2.488 −15.700 0.0023521 FRAS1 related extracellular matrix 1 LIPC 3.293 5.446 2.969 −0.834 1.493 −0.834 −15.495 0.0027757 lipase, hepatic LEPREL2 9.489 9.413 7.569 6.776 5.483 3.556 −15.242 0.0061184 leprecan-like 2 COL1A2 12.960 11.062 12.216 7.421 9.076 7.523 −14.763 0.0006199 collagen, type I, alpha 2 CCDC74A 2.837 3.050 3.281 −0.834 −0.834 −0.834 −14.760 0.0000889 coiled-coil domain containing 74A HAS1 7.726 9.916 9.883 5.326 6.063 5.345 −14.447 0.0013325 hyaluronan synthase 1 SPSB4 5.062 4.607 4.519 0.751 1.318 0.751 −13.624 0.0001116 splA/ryanodine receptor domain and SOCS box containing 4 FIGF 8.629 6.223 5.755 2.471 2.166 3.072 −13.476 0.0010201 c-fos induced growth factor (vascular endothelial growth factor D) RCC2 11.023 9.918 9.399 6.241 7.904 5.453 −12.791 0.0019573 regulator of chromosome condensation 2 LASS1 5.538 3.727 3.179 1.290 1.888 −0.834 −12.550 0.0072008 LAG1 homolog, ceramide synthase 1 CCL26 3.782 4.890 6.463 0.166 3.944 0.166 −12.262 0.0160079 chemokine (C-C motif) ligand 26 ARHGEF10L 7.126 9.060 8.778 4.560 6.872 3.558 −11.858 0.0094300 Rho guanine nucleotide exchange factor (GEF) 10-like HIC1 8.486 9.372 8.899 5.354 6.766 4.968 −11.453 0.0011229 hypermethylated in cancer 1 EN1 4.282 5.068 5.775 1.588 3.098 0.166 −11.161 0.0037266 engrailed homeobox 1 GPRC5A 9.571 11.352 10.095 8.432 6.646 5.332 −10.916 0.0046290 G protein-coupled receptor, family C, group 5, member A MATK 0.456 2.614 3.736 −0.834 −0.834 −0.834 −10.913 0.0069936 megakaryocyte-associated tyrosine kinase LOC390595 4.176 4.185 4.348 0.751 3.995 0.751 −10.737 0.0342742 No description CPZ 9.019 8.062 8.273 5.363 5.628 4.071 −10.488 0.0005745 carboxypeptidase Z TIMP1 11.217 10.873 12.597 11.095 7.732 7.533 −10.129 0.0306380 TIMP metallopeptidase inhibitor 1 CYP2E1 3.179 2.837 2.503 0.692 −0.834 −0.834 −10.104 0.0009210 cytochrome P450, family 2, subfamily E, polypeptide 1 RTN2 3.793 5.236 4.414 1.122 3.782 0.166 −9.795 0.0226464 reticulon 2 RCVRN 6.714 5.727 5.194 2.817 1.951 2.625 −9.468 0.0004731 recoverin ECEL1 9.036 4.888 5.727 2.488 3.950 2.488 −9.442 0.0120427 endothelin converting enzyme- like 1 PROK2 4.718 2.722 5.067 1.835 0.751 0.751 −9.397 0.0040427 prokineticin 2 PITX3 5.566 5.660 4.145 2.335 3.098 0.166 −9.391 0.0063741 paired-like homeodomain 3 UTP18 5.391 7.936 7.825 5.861 4.611 2.166 −9.278 0.0348007 UTP18, small subunit (SSU) processome component, homolog (yeast) DPP4 6.285 6.959 7.005 5.620 3.627 3.072 −9.270 0.0088567 dipeptidyl-peptidase 4 C15orf59 6.065 5.863 5.729 2.656 4.217 1.751 −9.231 0.0027530 chromosome 15 open reading frame 59 COL14A1 9.737 7.810 8.634 6.310 5.432 5.259 −9.198 0.0017417 collagen, type XIV, alpha 1 MFAP5 6.962 7.391 9.341 3.030 6.147 4.683 −9.155 0.0103793 microfibrillar associated protein 5 CPXM1 12.482 11.393 10.357 9.266 8.214 8.136 −9.052 0.0035246 carboxypeptidase X (M14 family), member 1 NAPSB 0.951 3.330 3.851 0.166 0.166 0.166 −8.963 0.0151486 napsin B aspartic peptidase pseudogene BAI2 8.195 5.627 4.428 2.488 3.380 2.488 −8.809 0.0097901 brain-specific angiogenesis inhibitor 2 THBS3 7.590 9.026 8.068 4.323 6.679 4.952 −8.668 0.0055344 thrombospondin 3 MYOC 2.764 5.590 7.336 2.487 2.857 0.751 −8.593 0.0274240 myocilin, trabecular meshwork inducible glucocorticoid response FAM159A 4.573 2.567 3.266 1.122 0.166 0.166 −8.570 0.0022213 family with sequence similarity 159, member A ABTB2 8.322 9.212 9.342 6.250 6.134 4.146 −8.527 0.0015473 ankyrin repeat and BTB (POZ) domain containing 2 DNM1 9.521 8.760 7.786 4.697 7.313 5.028 −8.506 0.0083188 dynamin 1 FZD1 7.300 5.233 5.578 3.368 4.184 2.166 −8.381 0.0084376 frizzled homolog 1 (Drosophila) CFD 13.706 18.067 16.205 12.861 13.235 13.143 −8.347 0.0249210 complement factor D (adipsin) CMA1 1.355 2.222 3.075 −0.834 −0.834 −0.834 −8.317 0.0008302 chymase 1, mast cell CD300A 0.456 2.222 2.837 −0.834 −0.834 −0.834 −8.317 0.0054315 CD300a molecule CXXC5 9.732 9.471 6.781 6.432 6.158 6.656 −8.218 0.0317568 CXXC finger protein 5 LOC389634 4.528 4.975 2.723 −0.834 1.493 2.165 −8.202 0.0122719 No description HPSE2 8.267 6.618 5.653 4.282 3.583 3.253 −8.198 0.0035132 heparanase 2 ARTN 4.354 5.631 3.455 2.609 2.092 0.166 −8.121 0.0112129 artemin PTK7 10.583 9.568 7.665 7.394 6.232 6.548 −8.113 0.0167530 PTK7 protein tyrosine kinase 7 LMNA 13.507 13.627 13.216 10.488 9.100 11.615 −8.102 0.0027001 lamin A/C C16orf93 3.168 3.389 2.861 0.166 0.166 0.166 −8.011 0.0001229 chromosome 16 open reading frame 93 SOX5 6.113 6.794 4.424 3.111 2.928 3.333 −8.009 0.0056933 SRY (sex determining region Y)- box 5 ECM1 10.046 10.838 10.912 9.039 7.467 7.048 −7.986 0.0035548 extracellular matrix protein 1 FNDC1 8.211 7.114 5.939 4.142 4.120 4.071 −7.968 0.0020526 fibronectin type III domain containing 1 ADORA2B 3.903 3.144 3.164 0.166 2.092 0.166 −7.880 0.0056592 adenosine A2b receptor EMILIN1 8.546 7.575 7.185 6.035 4.616 3.623 −7.779 0.0043400 elastin microfibril interfacer 1 GADD45G 6.611 7.312 7.747 4.850 3.661 3.960 −7.728 0.0007266 growth arrest and DNA-damage- inducible, gamma CXCL14 6.966 9.492 10.357 4.101 7.369 6.559 −7.636 0.0340541 chemokine (C-X-C motif) ligand 14 MEG3 13.477 13.408 14.632 11.318 11.709 10.177 −7.582 0.0024013 maternally expressed 3 (non- protein coding) WNT6 5.964 3.795 3.069 1.122 2.946 0.166 −7.480 0.0220359 wingless-type MMTV integration site family, member 6 MRC2 10.029 10.282 10.299 7.617 7.380 7.053 −7.477 0.0001834 mannose receptor, C type 2 XPNPEP2 4.059 4.873 6.008 1.974 2.821 1.974 −7.460 0.0030458 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane- bound ARC 10.064 11.106 12.064 8.135 8.213 8.393 −7.426 0.0018635 activity-regulated cytoskeleton- associated protein CNN1 8.806 7.865 7.619 5.160 5.920 4.404 −7.393 0.0014648 calponin 1, basic, smooth muscle WNT2 7.669 5.577 4.858 3.680 2.821 1.974 −7.385 0.0061486 wingless-type MMTV integration site family member 2 TMEM98 9.727 7.936 7.091 5.219 4.217 5.448 −7.328 0.0031978 transmembrane protein 98 IFT172 5.845 5.843 5.560 2.973 2.244 4.843 −7.310 0.0131554 intraflagellar transport 172 homolog (Chlamydomonas) ELN 12.244 10.753 9.930 7.460 7.382 9.382 −7.267 0.0092871 elastin DACT3 8.467 7.539 6.111 5.618 5.061 1.751 −7.203 0.0212137 dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis) CERCAM 11.232 9.912 7.728 7.230 7.073 6.948 −7.154 0.0232197 cerebral endothelial cell adhesion molecule TMEM88 7.608 8.493 8.419 4.614 7.948 5.580 −7.154 0.0476108 transmembrane protein 88 BLK 3.179 1.983 2.113 2.165 −0.834 −0.834 −7.045 0.0418181 B lymphoid tyrosine kinase NAPSA 2.745 3.965 0.692 −0.834 1.161 −0.834 −6.981 0.0290382 napsin A aspartic peptidase HMX1 2.946 4.483 3.795 2.946 0.951 0.166 −6.869 0.0234497 H6 family homeobox 1 COL3A1 11.385 10.918 9.981 5.875 8.644 8.597 −6.686 0.0088983 collagen, type III, alpha 1 C1QTNF4 5.283 3.858 3.636 1.122 3.362 0.166 −6.663 0.0203113 C1q and tumor necrosis factor related protein 4 ITIH4 4.569 4.065 4.683 1.835 1.977 0.751 −6.657 0.0006570 inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein) SEMA4A 10.502 11.179 10.454 7.729 7.732 9.218 −6.610 0.0032969 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A FLNC 8.741 8.647 8.304 6.043 5.922 4.557 −6.608 0.0007886 filamin C, gamma MST1 3.941 2.969 1.888 −0.834 −0.834 2.165 −6.597 0.0236055 macrophage stimulating 1 (hepatocyte growth factor-like) FGD1 7.389 7.322 5.800 5.763 2.488 4.601 −6.592 0.0271554 FYVE, RhoGEF and PH domain containing 1 MFGE8 10.788 10.952 10.969 8.235 10.194 7.883 −6.573 0.0181940 milk fat globule-EGF factor 8 protein HSP90AB1 12.181 12.296 14.984 9.581 12.701 8.810 −6.567 0.0485178 heat shock protein 90 kDa alpha (cytosolic), class B member 1 SFRP2 7.304 6.039 6.797 4.102 5.163 2.626 −6.476 0.0075927 secreted frizzled-related protein 2 WISP2 5.901 8.146 9.030 3.874 6.338 5.125 −6.462 0.0324081 WNT1 inducible signaling pathway protein 2 MMP2 12.299 11.743 11.503 11.614 9.064 6.737 −6.404 0.0468453 matrix metal lopeptidase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) USP2 6.132 5.982 6.696 5.275 3.460 3.253 −6.374 0.0109270 ubiquitin specific peptidase 2 VCAN 9.685 9.702 10.671 9.606 7.031 6.441 −6.372 0.0334444 versican BDKRB1 7.902 8.921 8.284 7.429 5.617 3.069 −6.350 0.0237984 bradykinin receptor B1 PRKCG 3.699 4.833 6.248 2.672 2.166 2.166 −6.349 0.0078733 protein kinase C, gamma RAP1GAP 7.490 5.053 3.315 2.392 3.315 1.751 −6.325 0.0313306 RAP1 GTPase activating protein ZFPM1 7.532 8.620 6.500 6.709 4.571 3.842 −6.312 0.0265291 zinc finger protein, multitype 1 COL16A1 10.454 9.136 9.973 7.317 6.996 7.424 −6.306 0.0011418 collagen, type XVI, alpha 1 CILP 10.250 11.238 11.023 8.641 7.738 7.597 −6.289 0.0008869 cartilage intermediate layer protein, nucleotide pyrophosphohydrolase SEMA5B 4.968 4.917 3.832 2.270 3.048 0.751 −6.265 0.0090980 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B CCDC80 11.647 12.727 12.687 9.445 11.000 9.008 −6.228 0.0067916 coiled-coil domain containing 80 ERF 10.371 10.555 8.974 7.442 7.091 7.928 −6.179 0.0035019 Ets2 repressor factor PCOLCE 8.738 7.363 7.122 5.819 5.226 4.497 −6.169 0.0046403 procollagen C-endopeptidase enhancer COL5A1 11.329 8.614 8.102 5.479 6.630 6.150 −6.158 0.0075095 collagen, type V, alpha 1 FSTL1 13.159 11.426 12.792 9.806 10.538 9.295 −6.150 0.0045972 follistatin-like 1 MAPKAPK2 13.745 13.653 11.924 10.918 11.016 11.137 −6.096 0.0115216 mitogen-activated protein kinase- activated protein kinase 2 HTRA3 5.938 7.304 5.967 4.000 3.447 3.336 −6.073 0.0012765 HtrA serine peptidase 3 ACP5 7.749 7.731 7.559 4.999 5.122 6.968 −5.898 0.0182129 acid phosphatase 5, tartrate resistant BICD1 4.304 3.069 2.946 1.588 1.755 0.166 −5.854 0.0102674 bicaudal D homolog 1 (Drosophila) RAET1G 3.709 3.736 2.414 2.165 1.161 −0.834 −5.848 0.0237666 retinoic acid early transcript 1G FAM180B 5.482 7.637 5.711 2.946 3.168 3.456 −5.826 0.0020866 family with sequence similarity 180, member B SOX8 7.577 7.608 7.511 5.044 4.805 5.577 −5.786 0.0004353 SRY (sex determining region Y)- box 8 BGN 10.733 10.661 10.861 7.913 8.674 8.203 −5.776 0.0003340 biglycan LTBP3 12.203 11.997 10.665 9.190 9.383 9.677 −5.760 0.0052039 latent transforming growth factor beta binding protein 3 OSR1 7.786 8.105 7.910 7.751 5.390 3.852 −5.735 0.0484172 odd-skipped related 1 (Drosophila) SFRP4 12.765 12.325 11.074 10.941 9.482 8.588 −5.602 0.0177334 secreted frizzled-related protein 4 PCDH7 6.088 4.819 4.073 3.576 2.334 1.751 −5.598 0.0127682 protocadherin 7 CLEC11A 5.894 5.966 5.606 3.412 3.757 1.488 −5.586 0.0030193 C-type lectin domain family 11, member A ZNF574 5.608 5.970 5.566 4.337 3.126 1.974 −5.585 0.0062197 zinc finger protein 574 BHLHE40 13.832 14.127 12.890 11.649 10.762 10.966 −5.569 0.0018892 basic helix-loop-helix family, member e40 HBB 8.833 9.189 13.402 6.357 8.229 7.760 −5.566 0.0408075 hemoglobin, beta COL9A3 8.069 4.616 4.978 2.144 3.315 2.866 −5.545 0.0132190 collagen, type IX, alpha 3 SLC25A44 9.088 9.707 10.072 6.637 8.712 6.618 −5.541 0.0143045 solute carrier family 25, member 44 ZNF503 6.661 6.833 8.813 5.902 6.023 4.199 −5.508 0.0384452 zinc finger protein 503 SCO2 7.667 8.821 8.979 6.568 4.907 6.361 −5.503 0.0056819 SCO cytochrome oxidase deficient homolog 2 (yeast) LPHN1 10.172 9.646 7.710 7.187 6.550 7.561 −5.498 0.0272598 latrophilin 1 SULF1 7.078 7.125 8.336 4.420 5.883 5.350 −5.475 0.0068491 sulfatase 1 CD276 10.934 9.392 10.543 8.489 8.353 5.664 −5.447 0.0156169 CD276 molecule RELT 6.300 7.620 6.272 5.178 4.541 2.336 −5.435 0.0144308 RELT tumor necrosis factor receptor CBX8 5.137 4.711 4.678 2.698 2.487 0.751 −5.425 0.0023151 chromobox homolog 8 MARCKSL1 8.607 8.635 8.585 6.168 6.502 4.666 −5.422 0.0017530 MARCKS-like 1 MXRA8 10.621 11.069 10.886 6.260 9.562 8.451 −5.410 0.0135594 matrix-remodelling associated 8 CTHRC1 7.154 7.569 8.036 5.237 5.607 3.528 −5.384 0.0036418 collagen triple helix repeat containing 1 SH3GL3 4.401 4.380 2.270 1.453 1.977 0.751 −5.368 0.0170760 SH3-domain GRB2-like 3 SELP 7.786 9.421 8.837 5.999 5.362 8.089 −5.368 0.0342629 selectin P (granule membrane protein 140 kDa, antigen CD62) APOE 14.930 14.604 13.036 11.108 12.186 12.268 −5.346 0.0101449 apolipoprotein E BST1 4.248 5.153 5.916 1.835 4.726 2.487 −5.329 0.0468680 bone marrow stromal cell antigen 1 SELE 4.163 5.887 6.860 4.276 3.480 3.254 −5.304 0.0386774 selectin E PTPRN 7.450 4.379 4.151 2.539 1.974 1.974 −5.299 0.0095443 protein tyrosine phosphatase, receptor type, N COL18A1 9.870 9.350 9.512 8.350 6.292 7.112 −5.279 0.0072515 collagen, type XVIII, alpha 1 CPSF7 8.886 8.924 9.494 7.726 6.368 6.529 −5.262 0.0039694 cleavage and polyadenylation specific factor 7, 59 kDa SNORD10 3.075 2.745 4.264 0.692 3.075 −0.834 −5.216 0.0494784 small nucleolar RNA, C/D box 10 LCNL1 1.880 3.352 3.134 0.751 0.751 0.751 −5.216 0.0062477 lipocalin-like 1 RASL10A 6.272 5.248 3.669 2.702 2.866 3.411 −5.214 0.0259747 RAS-like, family 10, member A FBLN1 12.263 12.006 12.396 10.835 9.883 8.808 −5.207 0.0057538 fibulin 1 BCL9L 11.205 10.928 8.987 8.856 8.142 7.853 −5.096 0.0227939 B-cell CLL/lymphoma 9-like MICALL2 5.742 6.452 5.902 3.966 4.108 2.751 −5.076 0.0025049 MICAL-like 2 UCN2 5.381 3.972 4.292 1.949 3.357 1.488 −5.074 0.0120163 urocortin 2 PODN 11.171 11.247 10.419 8.892 8.733 8.829 −5.068 0.0012992 podocan AHDC1 8.736 9.196 7.039 6.795 6.400 5.502 −5.049 0.0227598 AT hook, DNA binding motif, containing 1 CHKB 6.144 6.118 6.812 4.069 3.782 4.072 −5.049 0.0005337 choline kinase beta CHRD 8.599 9.242 8.286 6.266 6.965 5.662 −5.037 0.0023824 chordin NTN5 5.472 4.853 3.250 1.722 3.142 1.166 −5.028 0.0156479 netrin 5 PITPNM3 6.751 5.196 3.440 3.061 2.702 2.866 −5.027 0.0319996 PITPNM family member 3 SLC26A10 6.765 5.359 5.076 4.203 3.030 2.866 −5.024 0.0086244 solute carrier family 26, member 10 WDR52 8.249 7.333 6.939 5.109 4.365 5.923 −5.012 0.0057387 WD repeat domain 52 FAM46A 9.929 8.424 10.218 8.616 7.606 5.418 −5.004 0.0409754 family with sequence similarity 46, member A CSF1 8.358 8.450 7.618 7.024 5.362 5.296 −5.000 0.0090110 colony stimulating factor 1 (macrophage) ABCA6 4.023 5.075 6.111 2.931 2.753 2.166 −4.999 0.0063098 ATP-binding cassette, sub-family A (ABC1), member 6 GALNTL1 7.377 6.100 4.230 3.784 3.784 3.485 −4.981 0.0299573 UDP-N-acetyl-alpha-D- galactosamine:polypeptide N- acetylgalactosaminyltransferase- like 1 GPNMB 9.337 10.647 10.157 8.339 7.832 7.059 −4.954 0.0049512 glycoprotein (transmembrane) nmb EMP3 9.508 10.637 10.771 9.041 8.330 6.899 −4.950 0.0168468 epithelial membrane protein 3 AEBP1 6.653 7.033 5.897 4.825 4.353 3.336 −4.924 0.0048196 AE binding protein 1 DYRK2 6.957 6.628 6.740 6.004 4.442 3.919 −4.918 0.0175662 dual-s pecificity tyrosine-(Y)- phosphorylation regulated kinase 2 SLC7A3 5.963 3.048 3.048 0.751 1.318 0.751 −4.913 0.0081199 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 C11orf9 4.522 4.057 3.145 2.229 1.488 1.488 −4.899 0.0047878 chromosome 11 open reading frame 9 HSPB8 6.654 6.913 8.729 4.526 6.301 4.624 −4.884 0.0229013 heat shock 22 kDa protein 8 TMEM63B 9.852 10.514 9.074 7.716 7.564 6.976 −4.884 0.0025390 transmembrane protein 63B APOC1 11.023 11.789 10.004 7.600 8.743 9.825 −4.856 0.0222402 apolipoprotein C-I SGMS2 5.393 5.647 7.345 4.146 5.066 2.974 −4.851 0.0336207 sphingomyelin synthase 2 CREB3L1 7.095 6.860 6.455 5.245 4.588 2.867 −4.830 0.0073975 cAMP responsive element binding protein 3-like 1 SLC38A5 6.547 5.023 6.447 3.652 4.392 2.751 −4.828 0.0084225 solute carrier family 38, member 5 WDR86 7.421 7.427 4.581 2.911 5.158 4.119 −4.820 0.0394769 WD repeat domain 86 NGFR 7.023 7.135 6.762 3.920 5.195 4.755 −4.819 0.0017114 nerve growth factor receptor AKAP13 8.933 9.648 10.569 8.549 7.193 6.668 −4.806 0.0149686 A kinase (PRKA) anchor protein 13 PVRL1 8.826 9.526 8.196 7.266 6.525 6.386 −4.792 0.0053151 poliovirus receptor-related 1 (herpesvirus entry mediator C) MYO15B 9.286 8.727 7.944 5.433 6.963 7.025 −4.792 0.0118831 myosin XVB pseudogene ETV5 6.412 5.000 5.733 3.107 4.745 2.751 −4.752 0.0174565 ets variant 5 CLCN7 7.313 8.217 8.684 5.971 7.529 3.751 −4.743 0.0478741 chloride channel 7 LOXL1 8.421 6.301 7.060 5.701 4.140 4.817 −4.735 0.0130654 lysyl oxidase-like 1 MUSTN1 5.070 5.842 5.312 2.799 4.695 3.069 −4.734 0.0221494 musculoskeletal, embryonic nuclear protein 1 UBASH3B 8.060 8.264 8.413 6.024 6.323 3.751 −4.726 0.0058612 ubiquitin associated and SH3 domain containing B SMO 5.899 4.380 4.862 2.626 3.219 2.626 −4.711 0.0046176 smoothened homolog (Drosophila) GLT25D2 5.161 4.580 4.943 2.928 2.750 1.488 −4.703 0.0020753 glycosyltransferase 25 domain containing 2 HMOX1 13.282 15.360 14.604 11.923 13.128 12.011 −4.697 0.0207697 heme oxygenase (decycling) 1 FNIP2 7.887 8.790 9.738 7.396 6.454 6.563 −4.683 0.0154852 folliculin interacting protein 2 ATP10A 5.921 6.141 7.046 4.385 4.827 3.166 −4.655 0.0082924 ATPase, class V, type 10A IER3 13.332 14.070 12.999 12.699 11.114 9.490 −4.653 0.0272485 immediate early response 3 NECAB2 3.913 3.409 2.968 2.487 0.751 0.751 −4.649 0.0137954 N-terminal EF-hand calcium binding protein 2 CACNA2D2 3.777 4.276 3.705 1.488 3.416 1.488 −4.649 0.0315390 calcium channel, voltage- dependent, alpha 2/delta subunit 2 REEP5 7.971 7.863 9.110 5.756 7.692 4.865 −4.642 0.0311199 receptor accessory protein 5 OLFML3 6.578 4.770 5.564 3.404 4.364 2.488 −4.641 0.0171214 olfactomedin-like 3 STMN3 8.981 9.216 8.535 6.941 6.332 6.768 −4.637 0.0010654 stathmin-like 3 PYGO1 4.190 4.323 3.256 2.911 1.977 0.751 −4.636 0.0207167 pygopus homolog 1 (Drosophila) SPON2 10.831 10.397 10.225 9.689 8.014 8.080 −4.631 0.0172160 spondin 2, extracellular matrix protein RABGEF1 10.561 9.926 9.736 8.362 7.824 6.705 −4.592 0.0036812 RAB guanine nucleotide exchange factor (GEF) 1 CPEB1 5.919 6.994 5.361 4.801 4.217 1.751 −4.571 0.0265140 cytoplasmic polyadenylation element binding protein 1 COL5A2 9.041 7.943 7.971 5.753 6.500 6.148 −4.562 0.0031025 collagen, type V, alpha 2 RAP1GAP2 7.210 5.805 5.355 4.003 5.018 3.166 −4.561 0.0253990 RAP1 GTPase activating protein 2 PI4KAP1 1.355 1.888 1.663 0.692 −0.834 −0.834 −4.560 0.0113446 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1 VGF 2.067 2.424 1.355 −0.834 1.161 −0.834 −4.560 0.0194656 VGF nerve growth factor inducible ZNF775 2.424 3.247 1.355 −0.834 1.493 −0.834 −4.560 0.0236282 zinc finger protein 775 SUSD2 5.861 4.990 4.350 3.072 3.627 2.166 −4.544 0.0115662 sushi domain containing 2 BMP1 9.427 8.410 8.265 7.245 6.802 4.892 −4.539 0.0150382 bone morphogenetic protein 1 SPAG7 8.035 8.789 9.325 6.607 7.524 5.251 −4.539 0.0162969 sperm associated antigen 7 GGT5 8.459 8.148 7.904 5.241 6.476 5.972 −4.518 0.0019868 gamma-glutamyltransferase 5 C17orf96 6.982 5.509 5.716 4.283 4.718 3.335 −4.511 0.0174247 chromosome 17 open reading frame 96 NR2E3 3.144 2.174 2.335 0.166 0.166 0.166 −4.497 0.0008983 nuclear receptor subfamily 2, group E, member 3 C1QL1 2.639 2.335 0.420 0.166 0.166 0.166 −4.497 0.0486827 complement component 1, q subcomponent-like 1 GATAD2A 10.421 10.363 10.052 9.091 8.197 7.876 −4.488 0.0056706 GATA zinc finger domain containing 2A NT5E 7.901 8.117 8.220 7.024 5.952 5.108 −4.485 0.0105306 5′-nucleotidase, ecto (CD73) TNFRSF18 7.799 8.266 6.147 5.925 5.057 5.634 −4.484 0.0288952 tumor necrosis factor receptor superfamily, member 18 AGPAT4 7.983 8.139 7.851 6.972 5.824 5.409 −4.466 0.0093287 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) SFRS15 7.447 7.134 7.564 6.094 5.288 4.155 −4.465 0.0079240 No description APOL4 6.238 5.639 4.610 3.394 3.752 3.485 −4.448 0.0092530 apolipoprotein L, 4 ZNF408 6.983 7.160 6.937 4.833 5.965 3.558 −4.440 0.0129966 zinc finger protein 408 ST5 7.999 8.149 8.186 5.369 7.245 5.999 −4.439 0.0148249 suppression of tumorigenicity 5 PGAM1 6.888 6.757 6.193 5.907 4.607 3.163 −4.437 0.0303597 phosphoglycerate mutase 1 (brain) RFX2 7.649 8.190 7.556 6.046 5.913 4.899 −4.421 0.0029648 regulatory factor X, 2 (influences HLA class II expression) SOD3 9.931 9.849 9.058 7.709 4.199 8.776 −4.408 0.0448400 superoxide dismutase 3, extracellular COL6A2 14.769 14.954 14.199 13.232 12.451 12.060 −4.405 0.0043514 collagen, type VI, alpha 2 TICAM1 6.481 7.080 7.363 4.344 5.409 4.634 −4.399 0.0029089 toll-like receptor adaptor molecule 1 LTBP1 8.799 8.538 7.900 8.053 5.765 5.968 −4.394 0.0426244 latent transforming growth factor beta binding protein 1 IL2RB 1.641 3.179 4.467 2.335 0.166 0.166 −4.382 0.0481184 interleukin 2 receptor, beta ITGA11 6.090 8.113 5.954 3.608 4.357 5.987 −4.366 0.0476312 integrin, alpha 11 SAFB 5.744 5.580 7.130 5.006 4.165 3.072 −4.359 0.0226237 scaffold attachment factor B FAT1 8.181 8.466 8.452 6.329 6.834 5.095 −4.356 0.0049792 FAT tumor suppressor homolog 1 (Drosophila) HDX 3.168 2.639 2.289 0.166 2.092 0.166 −4.354 0.0270995 highly divergent homeobox ADAM33 6.448 6.081 5.000 3.550 3.961 4.164 −4.347 0.0084633 ADAM metallopeptidase domain 33 MINPP1 3.828 2.857 3.163 2.911 0.751 0.751 −4.304 0.0426895 multiple inositol-polyphosphate phosphatase 1 KCNAB3 4.190 3.527 3.852 2.270 1.748 0.751 −4.300 0.0038642 potassium voltage-gated channel, shaker-related subfamily, beta member 3 DFNB31 7.305 6.566 6.050 5.546 4.029 3.951 −4.285 0.0123567 deafness, autosomal recessive 31 ARL4D 4.270 5.696 5.804 2.821 3.710 3.596 −4.272 0.0169225 ADP-ribosylation factor-like 4D UGCG 6.268 6.823 7.694 6.146 4.731 3.724 −4.265 0.0293498 UDP-glucose ceramide glucosyltransferase HSD17B14 5.622 5.472 4.539 3.379 4.020 −0.834 −4.264 0.0401207 hydroxysteroid (17-beta) dehydrogenase 14 THY1 9.375 7.949 8.165 5.479 6.391 7.286 −4.256 0.0164777 Thy-1 cell surface antigen FLJ45445 9.124 9.025 7.699 7.213 2.092 6.936 −4.255 0.0436668 No description CLDN11 7.130 6.922 6.255 5.131 4.035 4.837 −4.242 0.0040034 claudin 11 UBE2Q2P3 4.072 3.069 3.565 2.567 1.484 0.166 −4.230 0.0189747 ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 3 EGFL8 5.709 6.427 6.171 4.091 5.161 1.751 −4.228 0.0279966 EGF-like-domain, multiple 8 SLC22A16 3.913 3.048 2.764 1.835 0.751 0.751 −4.224 0.0062666 solute carrier family 22 (organic cation/carnitine transporter), member 16 MEIS2 5.802 6.482 7.144 4.358 5.068 3.919 −4.218 0.0086471 Meis homeobox 2 TNC 7.702 5.973 5.147 4.688 4.755 3.073 −4.211 0.0382856 tenascin C KIFC2 7.376 7.900 6.139 5.302 5.748 4.899 −4.210 0.0200337 kinesin family member C2 MEIS3 8.571 8.176 7.482 6.385 6.503 5.184 −4.194 0.0088756 Meis homeobox 3 PDE4DIP 7.563 7.239 7.589 5.497 6.282 4.676 −4.189 0.0081086 phosphodiesterase 4D interacting protein CDK3 6.904 6.808 8.188 4.151 6.171 4.843 −4.171 0.0155132 cyclin-dependent kinase 3 RRBP1 6.586 6.352 7.693 5.262 5.641 4.191 −4.147 0.0209278 ribosome binding protein 1 homolog 180 kDa (dog) TRIM3 8.523 9.254 7.691 6.556 6.475 6.324 −4.136 0.0061297 tripartite motif-containing 3 LRP1 12.017 11.130 11.262 9.693 9.969 8.793 −4.135 0.0067349 low density lipoprotein receptor- related protein 1 PLTP 10.539 10.702 10.852 8.791 8.592 8.656 −4.130 0.0003635 phospholipid transfer protein PALM3 2.952 2.986 1.122 0.166 0.951 0.166 −4.100 0.0231638 paralemmin 3 UST 6.227 5.911 5.432 4.788 3.877 2.867 −4.097 0.0142190 uronyl-2-sulfotransferase CNTN4 4.365 4.269 3.024 1.751 2.334 1.751 −4.088 0.0087780 contactin 4 SDHA 3.815 3.865 2.317 1.835 1.318 0.751 −4.087 0.0133922 succinate dehydrogenase complex, subunit A, flavoprotein (Fp) LRP5L 6.408 6.216 5.694 5.282 4.185 1.974 −4.085 0.0328037 low density lipoprotein receptor- related protein 5-like SOLH 8.101 8.793 9.374 7.522 6.765 5.190 −4.079 0.0172772 small optic lobes homolog (Drosophila) MRAP2 4.848 4.192 4.468 2.821 2.821 1.974 −4.076 0.0033249 melanocortin 2 receptor accessory protein 2 GTF3C1 8.723 7.940 6.592 6.073 5.925 5.486 −4.043 0.0211797 general transcription factor IIIC, polypeptide 1, alpha 220 kDa FOXK2 9.620 9.864 8.865 8.867 7.605 6.824 −4.039 0.0394149 forkhead box K2 MEF2D 10.416 10.515 8.992 8.502 8.140 7.797 −4.035 0.0163967 myocyte enhancer factor 2D MAP1A 8.635 9.393 8.284 7.384 6.803 5.874 −4.024 0.0091524 microtubule-associated protein 1A KCNE1L 2.249 2.174 2.639 0.166 1.484 0.166 −4.023 0.0141123 KCNE1-like HYLS1 4.573 4.282 4.603 3.275 2.567 0.166 −4.018 0.0198741 hydrolethalus syndrome 1 AFAP1L2 4.278 3.604 2.242 2.045 1.611 1.166 −3.979 0.0311653 actin filament associated protein 1-like 2 APOD 17.920 16.308 15.955 16.180 13.059 14.316 −3.977 0.0477697 apolipoprotein D SPSB1 10.760 11.556 10.295 10.192 8.310 8.343 −3.960 0.0284626 splA/ryanodine receptor domain and SOCS box containing 1 PPTC7 4.735 4.890 5.343 4.329 2.751 2.751 −3.957 0.0243423 PTC7 protein phosphatase homolog (S. cerevisiae) NBLA00301 4.072 4.796 3.144 3.164 2.092 0.166 −3.945 0.0386887 No description MAPKBP1 6.004 6.709 6.158 4.184 5.761 3.625 −3.927 0.0338733 mitogen-activated protein kinase binding protein 1 SSC5D 9.833 9.447 8.304 7.801 6.331 7.788 −3.926 0.0252334 No description GGT7 6.050 6.077 6.170 4.104 5.285 3.556 −3.926 0.0166078 gamma-glutamyltransferase 7 TAF1D 9.993 10.144 10.365 9.115 8.172 7.011 −3.921 0.0135367 TATA box binding protein (TBP)- associated factor, RNA polymerase I, D, 41 kDa C1orf92 3.709 2.424 0.995 0.692 0.456 −0.834 −3.911 0.0268635 chromosome 1 open reading frame 92 H2AFX 7.242 7.347 8.044 5.380 6.635 3.784 −3.910 0.0224436 H2A histone family, member X FAM18A 4.537 3.629 2.572 2.572 1.488 1.488 −3.905 0.0364531 family with sequence similarity 18, member A ZC3H12A 5.038 5.605 4.768 4.348 3.076 1.974 −3.895 0.0244974 zinc finger CCCH-type containing 12A TMEM132C 4.762 4.566 4.377 2.610 3.874 2.336 −3.882 0.0220836 transmembrane protein 132C SLCO5A1 3.712 3.445 4.296 2.928 1.488 1.488 −3.881 0.0162704 solute carrier organic anion transporter family, member 5A1 ALPL 8.915 7.617 6.959 4.536 5.865 6.963 −3.868 0.0398650 alkaline phosphatase, liver/bone/ kidney TBC1D26 4.072 3.069 1.862 1.122 1.755 0.166 −3.856 0.0313544 TBC1 domain family, member 26 PRRG3 2.698 2.968 1.748 0.751 0.751 0.751 −3.854 0.0088453 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) WDR62 4.792 3.852 2.698 2.487 1.977 0.751 −3.854 0.0284308 WD repeat domain 62 SHC3 2.698 4.271 2.949 2.270 1.748 0.751 −3.854 0.0358695 SHC (Src homology 2 domain containing) transforming protein 3 CPXM2 8.840 8.668 8.663 5.885 6.726 6.970 −3.844 0.0016774 carboxypeptidase X (M14 family), member 2 HS6ST1 8.735 8.975 8.567 7.033 6.919 5.103 −3.843 0.0066222 heparan sulfate 6-O-sulfotransferase 1 GZMB 2.565 3.108 4.516 1.166 1.166 1.166 −3.842 0.0075397 granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) PLXDC1 9.292 8.368 9.285 6.301 8.171 7.344 −3.839 0.0319520 plexin domain containing 1 IL6R 7.879 8.152 9.447 7.506 6.594 5.449 −3.838 0.0296554 interleukin 6 receptor NUDT11 3.221 3.256 3.578 2.793 1.318 0.751 −3.830 0.0299762 nudix (nucleoside diphosphate linked moiety X)-type motif 11 WNK4 6.249 4.171 3.993 2.392 2.062 2.866 −3.812 0.0129505 WNK lysine deficient protein kinase 4 UPF1 10.273 9.083 9.729 8.102 7.798 7.233 −3.812 0.0059671 UPF1 regulator of nonsense transcripts homolog (yeast) CCNK 7.396 7.041 8.167 6.172 6.239 4.567 −3.804 0.0231751 cyclin K CD7 5.682 6.311 7.163 5.236 3.302 4.492 −3.804 0.0206380 CD7 molecule COL6A1 9.763 9.951 10.041 8.025 9.390 6.750 −3.801 0.0371282 collagen, type VI, alpha 1 PTGIS 4.569 6.130 4.762 4.204 3.596 2.488 −3.800 0.0406638 prostaglandin I2 (prostacyclin) synthase MKI67IP 5.621 6.920 7.136 5.211 5.074 3.250 −3.799 0.0274913 MKI67 (FHA domain) interacting nucleolar phosphoprotein COL2A1 1.862 2.092 2.174 0.166 0.166 0.166 −3.798 0.0005110 collagen, type II, alpha 1 SLC6A1 2.092 3.248 1.484 0.166 0.166 0.166 −3.798 0.0072213 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 HPCA 2.092 2.152 0.759 0.166 0.166 0.166 −3.798 0.0269051 hippocalcin F10 6.052 6.267 5.730 4.250 4.343 1.751 −3.797 0.0128370 coagulation factor X KDM6B 14.307 13.889 13.038 12.482 11.122 11.719 −3.776 0.0117439 lysine (K)-specific demethylase 6B SLIT3 6.145 6.252 7.272 4.593 5.357 3.810 −3.769 0.0138544 slit homolog 3 (Drosophila) COL7A1 5.448 4.230 5.716 2.853 3.811 2.626 −3.744 0.0122833 collagen, type VII, alpha 1 PELI2 6.282 5.365 6.003 4.379 4.177 3.336 −3.739 0.0066857 pel lino homolog 2 (Drosophila) OMD 3.068 3.907 4.723 2.045 2.817 1.166 −3.737 0.0256078 osteomodulin SYN1 3.637 3.483 3.512 2.817 1.611 1.166 −3.734 0.0198627 synapsin I PRRT2 4.863 5.688 4.442 2.429 2.965 4.002 −3.727 0.0190420 proline-rich transmembrane protein 2 MIB2 8.044 9.177 8.446 6.273 7.779 6.149 −3.720 0.0242092 mindbomb homolog 2 (Drosophila) EGLN3 4.620 3.646 4.873 2.702 3.254 1.751 −3.718 0.0205624 egl nine homolog 3 (C. elegans) CD14 6.344 8.239 7.930 5.047 6.352 5.666 −3.699 0.0328801 CD14 molecule IGHMBP2 4.632 4.932 6.206 3.250 4.333 2.166 −3.664 0.0300526 immunoglobulin mu binding protein 2 SGSM2 8.979 8.849 8.608 6.848 7.986 6.741 −3.648 0.0157190 small G protein signaling modulator 2 FAP 7.340 7.177 7.701 5.785 5.311 5.614 −3.647 0.0017228 fibroblast activation protein, alpha HPX 5.637 5.129 5.272 4.203 3.158 3.411 −3.632 0.0068710 hemopexin CACNA1C 6.597 5.753 4.934 4.272 4.097 3.073 −3.632 0.0173075 calcium channel, voltage-dependent, L type, alpha 1C subunit C16orf72 7.977 7.223 7.814 5.197 6.616 5.954 −3.631 0.0147099 chromosome 16 open reading frame 72 LRRC37B 5.045 5.107 5.180 3.015 4.128 3.250 −3.621 0.0092349 leucine rich repeat containing 37B KDM4A 5.768 5.265 4.941 4.761 2.318 3.411 −3.614 0.0375223 lysine (K)-specific demethylase 4A ERGIC3 8.251 7.520 8.641 6.398 4.119 6.972 −3.612 0.0262666 ERGIC and golgi 3 LRRN4CL 4.188 4.481 5.387 2.610 3.692 2.336 −3.610 0.0186214 LRRN4 C-terminal like PLXNA4 8.119 6.470 5.960 4.262 4.628 5.571 −3.586 0.0256849 plexin A4 C16orf65 2.165 3.727 2.424 0.692 1.888 −0.834 −3.577 0.0321494 No description WDR47 4.710 5.114 3.806 3.759 2.821 1.974 −3.562 0.0357908 WD repeat domain 47 NAT10 8.105 8.416 7.950 7.199 5.509 6.273 −3.560 0.0142931 N-acetyltransferase 10 (GCN5- related) PRDM2 7.392 7.236 8.207 7.023 5.563 5.252 −3.555 0.0352719 PR domain containing 2, with ZNF domain RHPN1 5.576 5.590 4.473 3.517 3.761 3.687 −3.554 0.0153771 rhophilin, Rho GTPase binding protein 1 SLC35E4 6.920 7.081 5.901 5.928 5.094 3.411 −3.547 0.0485405 solute carrier family 35, member E4 TRH 2.092 2.946 1.641 1.122 0.166 0.166 −3.541 0.0173521 thyrotropin-releasing hormone RAB17 4.263 3.569 3.981 2.165 3.075 −0.834 −3.520 0.0406282 RAB17, member RAS oncogene family GAS7 8.947 8.558 8.642 6.411 7.106 7.132 −3.520 0.0026683 growth arrest-specific 7 MFAP2 4.790 4.382 2.776 1.722 2.974 1.166 −3.519 0.0314255 microfibrillar-associated protein 2 CHSY3 2.817 2.981 4.260 1.166 1.611 1.166 −3.519 0.0069822 chondroitin sulfate synthase 3 MC1R 4.094 4.944 6.795 3.441 3.129 2.488 −3.518 0.0220004 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) FGFR3 7.573 7.669 5.322 4.659 3.771 5.855 −3.517 0.0439346 fibroblast growth factor receptor 3 DCHS1 8.122 7.596 8.133 6.495 6.308 5.466 −3.515 0.0054724 dachsous 1 (Drosophila) EP400 8.425 8.523 7.175 7.184 5.362 5.800 −3.515 0.0258498 E1A binding protein p400 LILRA5 3.048 3.110 3.266 1.453 1.318 0.751 −3.514 0.0014126 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 SMOC2 6.314 6.459 5.721 4.621 4.502 4.191 −3.512 0.0037840 SPARC related modular calcium binding 2 MAB21L1 2.609 1.974 1.752 0.166 0.166 0.166 −3.502 0.0017999 mab-21-like 1 (C. elegans) TMEM41B 6.893 5.065 6.599 5.085 4.631 4.011 −3.502 0.0437273 transmembrane protein 41B PKD2 8.458 8.635 8.406 7.294 6.652 6.591 −3.497 0.0039414 polycystic kidney disease 2 (autosomal dominant) TOP1 8.815 8.265 8.658 7.837 6.089 6.852 −3.497 0.0252787 topoisomerase (DNA) I IGFN1 6.606 5.481 5.161 3.682 4.388 3.559 −3.480 0.0127311 immunoglobulin-like and fibronectin type III domain containing 1 FN1 9.513 8.609 8.874 7.717 7.558 5.681 −3.473 0.0221607 fibronectin 1 CNPY4 7.355 6.216 5.298 4.159 4.941 4.424 −3.465 0.0285571 canopy 4 homolog (zebrafish) TRAF3 4.958 5.558 6.507 4.619 4.342 3.166 −3.463 0.0396532 TNF receptor-associated factor 3 PTPRU 6.672 6.752 6.380 5.152 4.888 4.071 −3.445 0.0043135 protein tyrosine phosphatase, receptor type, U EFHD2 10.926 12.094 11.617 10.309 10.030 9.065 −3.445 0.0180488 EF-hand domain family, member D2 GCNT4 3.256 3.163 2.533 0.751 1.748 0.751 −3.439 0.0064073 glucosaminyl (N-acetyl) transferase 4, core 2 DUSP8 8.043 8.055 7.216 6.276 6.120 5.917 −3.431 0.0063514 dual specificity phosphatase 8 LRRC41 7.124 7.231 8.551 5.348 6.999 5.356 −3.426 0.0415480 leucine rich repeat containing 41 MAST2 12.070 10.506 9.596 9.082 8.470 8.731 −3.423 0.0280685 microtubule associated serine/ threonine kinase 2 FRAT2 4.892 4.357 4.847 3.412 3.074 1.488 −3.418 0.0143196 frequently rearranged in advanced T-cell lymphomas 2 CRY1 8.855 8.905 9.507 7.734 7.445 5.560 −3.418 0.0160669 cryptochrome 1 (photolyase- like) KLHL21 8.818 8.756 10.183 7.052 8.414 5.209 −3.410 0.0327356 kelch-like 21 (Drosophila) DYSFIP1 3.858 4.066 2.559 2.567 2.092 0.166 −3.403 0.0487394 dysferlin interacting protein 1 RAB3IL1 7.544 8.672 8.074 6.308 7.334 4.528 −3.401 0.0373135 RAB3A interacting protein (rabin3)-like 1 FAM63A 5.351 5.262 3.874 3.586 2.804 3.336 −3.399 0.0299232 family with sequence similarity 63, member A RABEP1 8.148 8.078 7.287 6.316 6.996 5.501 −3.393 0.0292561 rabaptin, RAB GTPase binding effector protein 1 MAN1C1 4.439 4.154 3.618 2.392 2.867 1.751 −3.391 0.0103453 mannosidase, alpha, class 1C, member 1 DKFZp686O2 3.730 4.178 6.377 2.973 3.394 1.974 −3.379 0.0464020 No description 4166 TRIO 9.350 9.039 10.193 8.439 8.050 6.409 −3.373 0.0291010 triple functional domain (PTPRF interacting) PDGFRL 3.996 3.364 2.375 1.166 2.242 1.166 −3.372 0.0275261 platelet-derived growth factor receptor-like AUTS2 7.662 6.666 7.097 6.185 5.315 4.913 −3.371 0.0184489 autism susceptibility candidate 2 SPOCK1 4.918 4.176 5.413 3.444 3.071 3.166 −3.369 0.0130836 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 NPEPPS 7.767 8.079 8.521 7.254 6.331 5.976 −3.359 0.0187621 aminopeptidase puromycin sensitive XIRP1 6.975 6.571 7.274 6.202 4.351 5.228 −3.357 0.0280284 xin actin-binding repeat containing 1 KLF16 7.217 7.148 6.279 5.472 5.276 4.846 −3.352 0.0089512 Kruppel-like factor 16 WDFY2 6.527 7.078 7.321 5.881 5.334 4.760 −3.349 0.0132530 WD repeat and FYVE domain containing 2 LOC1001305 6.073 5.754 5.584 5.218 4.010 3.687 −3.349 0.0316184 No description 81 FCHO1 3.416 3.231 3.416 1.488 2.750 1.488 −3.348 0.0273453 FCH domain only 1 HES7 3.454 3.782 2.625 2.045 1.611 1.166 −3.334 0.0142379 hairy and enhancer of split 7 (Drosophila) RFPL3S 5.345 4.546 4.072 4.016 2.567 2.335 −3.332 0.0367092 RFPL3 antisense RNA (non- protein coding) FRMD4B 1.748 2.487 3.183 0.751 0.751 0.751 −3.331 0.0114739 FERM domain containing 4B IPMK 1.453 2.698 2.487 0.751 0.751 0.751 −3.331 0.0212364 inositol polyphosphate multikinase RAD9A 5.896 5.878 6.982 5.247 4.764 3.072 −3.328 0.0339157 RAD9 homolog A (S. pombe) ENGASE 6.672 6.794 7.346 5.064 6.322 4.326 −3.317 0.0322341 endo-beta-N- acetylglucosaminidase RNF152 3.830 5.107 5.160 3.433 2.817 3.250 −3.310 0.0266728 ring finger protein 152 EEF2 15.291 15.548 15.543 14.090 13.817 13.502 −3.307 0.0025276 eukaryotic translation elongation factor 2 MAPK13 4.597 4.086 4.581 3.048 2.857 0.751 −3.303 0.0178158 mitogen-activated protein kinase 13 SFMBT1 3.430 3.250 4.735 3.015 2.169 1.166 −3.295 0.0452712 Scm-like with four mbt domains 1 TNXB 5.554 6.390 5.987 4.269 4.249 4.624 −3.290 0.0065261 tenascin XB NFKB2 11.222 11.701 10.625 10.459 8.913 9.265 −3.277 0.0300374 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) C14orf169 6.984 7.763 6.084 6.168 3.841 5.272 −3.277 0.0467931 chromosome 14 open reading frame 169 PCSK9 6.193 2.878 2.587 1.166 1.166 1.166 −3.276 0.0249951 proprotein convertase subtilisin/ kexin type 9 ARID5A 11.705 10.682 9.919 9.485 8.208 9.695 −3.275 0.0480390 AT rich interactive domain 5A (MRF1-like) ZNF787 6.581 7.606 6.498 6.131 3.399 4.872 −3.268 0.0323325 zinc finger protein 787 LRRC4 4.009 4.613 4.825 2.906 3.017 2.488 −3.266 0.0059179 leucine rich repeat containing 4 HMHA1 2.485 4.393 4.335 2.687 1.166 1.166 −3.264 0.0280836 histocompatibility (minor) HA-1 SMG1 6.766 6.589 7.769 5.818 6.065 4.295 −3.257 0.0425707 SMG1 homolog, phosphatidylinositol 3-kinase- related kinase (C. elegans) MSI1 6.144 5.604 4.771 4.700 3.719 3.072 −3.245 0.0340957 musashi homolog 1 (Drosophila) RPL13AP20 1.484 1.862 1.974 0.166 0.166 0.166 −3.239 0.0020246 ribosomal protein L13a pseudogene 20 ZFP57 1.862 3.858 1.484 0.166 0.166 0.166 −3.239 0.0155480 zinc finger protein 57 homolog (mouse) MAP3K15 3.707 1.862 0.759 0.166 0.166 0.166 −3.239 0.0421486 mitogen-activated protein kinase kinase kinase 15 SKI 10.954 10.779 9.099 9.261 7.723 8.358 −3.234 0.0367515 v-ski sarcoma viral oncogene homolog (avian) C22orf9 8.868 9.083 9.814 7.824 8.121 6.630 −3.234 0.0213710 chromosome 22 open reading frame 9 METAP2 7.314 7.002 7.535 6.261 3.413 5.621 −3.233 0.0277863 methionyl aminopeptidase 2 POLR2D 6.310 6.415 6.682 6.033 4.724 3.897 −3.229 0.0441161 polymerase (RNA) II (DNA directed) polypeptide D ELF4 7.122 8.592 8.615 6.927 6.803 5.537 −3.222 0.0387523 E74-like factor 4 (ets domain transcription factor) TEX10 6.905 6.725 7.819 5.217 6.273 3.662 −3.222 0.0285299 testis expressed 10 C14orf176 3.391 3.201 2.854 1.166 2.484 1.166 −3.222 0.0253128 chromosome 14 open reading frame 176 GLIPR1 6.724 6.780 6.559 5.037 6.041 4.451 −3.219 0.0278317 GLI pathogenesis-related 1 FBLN2 6.727 7.384 6.694 4.277 5.040 6.231 −3.218 0.0275465 fibulin 2 RNF24 8.399 7.553 8.147 7.499 5.920 5.871 −3.209 0.0363809 ring finger protein 24 FAM22A 3.450 3.515 4.043 1.835 2.487 0.751 −3.204 0.0113135 family with sequence similarity 22, member A ZNRF3 5.653 5.444 5.562 3.884 4.116 3.558 −3.199 0.0019005 zinc and ring finger 3 KIAA1407 4.993 4.559 3.594 2.702 3.315 2.866 −3.199 0.0334066 KIAA1407 BCAR1 10.571 10.567 9.571 8.473 8.896 8.550 −3.194 0.0118476 breast cancer anti-estrogen resistance 1 GSN 14.460 14.862 14.463 12.944 12.276 13.187 −3.193 0.0044300 gelsolin BRD2 9.916 9.984 10.114 9.468 7.940 8.310 −3.191 0.0339883 bromodomain containing 2 ARL13B 8.118 7.627 8.174 6.998 6.232 5.955 −3.188 0.0126320 ADP-ribosylation factor-like 13B RCOR1 7.020 6.483 6.798 5.130 5.506 3.971 −3.176 0.0105533 REST corepressor 1 C5orf42 6.603 5.996 5.280 4.178 4.330 4.479 −3.172 0.0134376 chromosome 5 open reading frame 42 AMN 1.641 2.787 2.174 1.122 0.166 0.166 −3.170 0.0153105 amnionless homolog (mouse) MAFK 9.691 11.650 11.494 8.089 9.988 8.423 −3.164 0.0305420 v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) ICAM5 2.734 3.230 3.145 1.488 1.488 1.488 −3.154 0.0026494 intercellular adhesion molecule 5, telencephalin KNDC1 4.893 3.407 3.083 1.751 1.751 1.751 −3.150 0.0104444 kinase non-catalytic C-lobe domain (KIND) containing 1 MAFA 7.581 6.993 7.337 5.843 5.927 3.795 −3.147 0.0184716 v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) C17orf56 3.861 3.775 3.107 2.122 2.429 1.166 −3.145 0.0162439 chromosome 17 open reading frame 56 TUBBS 8.254 8.255 8.982 6.358 7.330 6.733 −3.143 0.0098317 tubulin, beta 3 CDK17 6.072 5.556 6.939 4.121 5.291 4.285 −3.133 0.0289399 cyclin-dependent kinase 17 ANGPTL4 12.527 12.023 13.089 11.442 10.927 9.977 −3.132 0.0187235 angiopoietin-like 4 MTA2 5.349 5.600 5.575 4.748 3.930 3.336 −3.128 0.0223423 metastasis associated 1 family, member 2 HIC2 5.576 5.470 6.343 4.676 4.699 3.414 −3.126 0.0311842 hypermethylated in cancer 2 PENK 6.491 2.969 3.498 1.949 1.854 1.488 −3.126 0.0283400 proenkephalin CTGF 11.616 11.043 12.859 9.859 9.975 10.133 −3.120 0.0162107 connective tissue growth factor ZFP36L1 10.453 10.604 12.985 9.491 9.464 8.812 −3.118 0.0309769 zinc finger protein 36, C3H type- like 1 INTS7 7.220 7.088 8.955 5.448 6.589 6.349 −3.117 0.0493536 integrator complex subunit 7 ACAN 2.817 3.250 2.429 1.166 1.611 1.166 −3.115 0.0092644 aggrecan CNTD2 7.806 6.865 5.778 5.566 5.230 4.985 −3.106 0.0437160 cyclin N-terminal domain containing 2 FADD 6.318 6.329 6.085 4.908 4.374 4.683 −3.105 0.0027871 Fas (TNFRSF6)-associated via death domain SCARA5 4.960 6.201 7.777 4.567 4.857 3.558 −3.104 0.0442379 scavenger receptor class A, member 5 (putative) IRF1 7.724 8.419 8.541 6.911 6.866 5.711 −3.094 0.0153219 interferon regulatory factor 1 MFHAS1 5.266 4.795 6.117 4.507 3.519 3.166 −3.092 0.0275972 malignant fibrous histiocytoma amplified sequence 1 TRIM45 2.965 3.348 3.512 1.722 2.429 1.166 −3.086 0.0202871 tripartite motif-containing 45 RARA 9.856 10.334 8.949 8.145 8.246 8.234 −3.077 0.0209731 retinoic acid receptor, alpha LOC284578 6.098 7.065 6.169 5.447 3.724 4.815 −3.070 0.0237780 No description CMYA5 3.685 3.445 3.101 1.488 2.339 1.488 −3.060 0.0087273 cardiomyopathy associated 5 TSC22D2 6.310 6.713 7.882 5.101 5.978 4.819 −3.056 0.0307727 TSC22 domain family, member 2 ZNF512B 6.023 5.569 4.538 3.961 4.272 3.919 −3.047 0.0436365 zinc finger protein 512B OLFML1 3.708 3.580 3.737 1.974 2.805 1.974 −3.044 0.0130079 olfactomedin-like 1 PTPN7 1.748 2.698 3.439 1.835 0.751 0.751 −3.041 0.0478627 protein tyrosine phosphatase, non-receptor type 7 C2orf89 4.072 4.170 4.218 2.567 0.166 3.456 −3.038 0.0450957 chromosome 2 open reading frame 89 VASN 6.993 6.180 6.005 5.786 4.577 4.199 −3.037 0.0389429 vasorin LPCAT3 6.928 8.506 7.248 4.860 6.932 5.649 −3.031 0.0482394 lysophosphatidylcholine acyltransferase 3 TGIF2 7.101 6.956 7.498 4.396 6.373 5.502 −3.031 0.0251623 TGFB-induced factor homeobox 2 MAPK8IP1 2.040 3.048 2.350 0.751 0.751 0.751 −3.030 0.0052356 mitogen-activated protein kinase 8 interacting protein 1 PBX2 8.073 8.758 7.847 6.187 7.172 6.697 −3.002 0.0179595 pre-B-cell leukemia homeobox 2 LOC1001296 3.319 4.068 3.975 2.144 2.490 1.751 −2.985 0.0074981 No description 37 ADAM12 7.243 5.180 5.831 4.390 4.261 3.810 −2.969 0.0196797 ADAM metallopeptidase domain 12 SCYL1 10.170 11.145 10.026 9.003 9.578 7.976 −2.962 0.0364815 SCY1-like 1 (S. cerevisiae) FBLN7 5.824 5.418 5.297 3.852 4.333 2.166 −2.961 0.0176025 fibulin 7 SIX2 4.216 4.316 4.905 2.750 4.021 1.488 −2.959 0.0489595 SIX homeobox 2 C14orf132 5.050 5.160 4.467 3.542 3.487 3.254 −2.954 0.0077674 chromosome 14 open reading frame 132 MLL4 8.455 8.207 7.985 7.698 6.424 6.580 −2.951 0.0394883 No description MECP2 9.341 8.720 7.943 7.783 7.346 6.013 −2.943 0.0460677 methyl CpG binding protein 2 (Rett syndrome) MTMR3 6.300 6.709 6.595 5.687 5.041 4.550 −2.936 0.0188090 myotubularin related protein 3 MMP14 7.207 6.952 7.712 6.166 5.957 2.974 −2.920 0.0403567 matrix metallopeptidase 14 (membrane-inserted) PLD3 10.265 9.404 9.285 7.747 8.358 8.722 −2.903 0.0328151 phospholipase D family, member 3 GPR124 6.945 5.347 5.389 4.087 4.765 3.810 −2.902 0.0317341 G protein-coupled receptor 124 JAMS 7.420 6.554 7.689 6.154 5.981 3.414 −2.898 0.0453166 junctional adhesion molecule 3 TMC5 6.471 5.169 5.625 5.056 4.090 2.488 −2.898 0.0454247 transmembrane channel-like 5 CTBP2 5.007 4.974 4.033 3.441 3.492 2.336 −2.895 0.0257455 C-terminal binding protein 2 FAM181B 0.692 2.165 2.222 0.692 −0.834 −0.834 −2.888 0.0225102 family with sequence similarity 181, member B BDKRB2 4.434 4.280 4.683 3.814 2.751 2.751 −2.886 0.0272001 bradykinin receptor B2 FBXL14 4.860 4.861 3.231 2.229 2.572 3.333 −2.883 0.0421131 F-box and leucine-rich repeat protein 14 ACE 4.550 6.689 5.811 3.107 4.485 4.285 −2.881 0.0481070 angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 NDRG1 10.753 11.448 11.702 9.230 10.262 9.268 −2.873 0.0138430 N-myc downstream regulated 1 UBIAD1 8.156 8.535 7.699 7.190 5.728 6.635 −2.870 0.0234194 UbiA prenyltransferase domain containing 1 KCNJ12 4.177 3.926 3.813 2.166 2.406 3.556 −2.869 0.0496834 potassium inwardly-rectifying channel, subfamily J, member 12 EVC 4.528 4.444 3.341 3.010 2.804 2.626 −2.865 0.0377992 Ellis van Creveld syndrome NAF1 6.452 6.490 5.331 5.216 3.815 4.697 −2.859 0.0399762 nuclear assembly factor 1 homolog (S. cerevisiae) SAMD4A 9.210 9.294 8.593 7.399 7.785 7.295 −2.846 0.0077296 sterile alpha motif domain containing 4A C5orf45 7.352 7.304 7.389 5.152 5.844 6.451 −2.844 0.0165329 chromosome 5 open reading frame 45 SLC22A17 8.012 7.762 7.438 6.256 6.592 4.899 −2.841 0.0174996 solute carrier family 22, member 17 MTSS1L 6.788 7.094 6.277 5.527 5.591 4.366 −2.835 0.0240412 metastasis suppressor 1-like PRKCZ 3.438 4.414 4.298 2.799 3.098 0.166 −2.826 0.0497644 protein kinase C, zeta TNKS1BP1 10.097 9.456 9.377 7.962 8.707 7.469 −2.817 0.0179391 tankyrase 1 binding protein 1, 182 kDa ZFAND2A 11.032 10.507 9.941 9.561 8.176 9.013 −2.816 0.0283778 zinc finger, AN1-type domain 2A PDCD7 6.558 5.859 6.257 4.690 5.455 4.365 −2.816 0.0260919 programmed cell death 7 TRIM28 11.497 11.320 11.303 9.829 10.615 8.810 −2.810 0.0267636 tripartite motif-containing 28 TTC7A 7.326 8.001 7.678 6.061 6.510 5.877 −2.810 0.0086131 tetratricopeptide repeat domain 7A ADAMTS14 3.826 3.897 3.760 2.336 2.336 2.336 −2.810 0.0011025 ADAM metallopeptidase with thrombospondin type 1 motif, 14 PHF23 5.722 5.467 5.422 3.978 4.577 2.866 −2.807 0.0188203 PHD finger protein 23 CDR2 7.675 7.724 7.972 6.783 6.238 5.767 −2.800 0.0107061 cerebellar degeneration-related protein 2, 62 kDa COL13A1 3.986 4.256 3.649 2.931 2.406 2.166 −2.795 0.0116154 collagen, type XIII, alpha 1 SLC7A1 7.146 7.376 7.628 6.477 5.895 3.810 −2.793 0.0344709 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 IER5 9.911 10.295 10.642 8.814 9.471 8.262 −2.791 0.0259936 immediate early response 5 MTMR11 4.710 4.936 5.427 3.456 3.681 3.250 −2.790 0.0060980 myotubularin related protein 11 LOC619207 2.968 3.287 1.949 1.488 1.488 1.488 −2.789 0.0444807 No description RUNX1T1 3.452 2.527 4.379 1.974 1.974 1.974 −2.787 0.0399164 runt-related transcription factor 1: translocated to, 1 (cyclin D- related) VTN 1.641 2.386 1.588 0.166 0.166 0.166 −2.780 0.0040314 vitronectin GNG8 2.249 2.946 1.641 1.588 0.166 0.166 −2.780 0.0352122 guanine nucleotide binding protein (G protein), gamma 8 EHD1 9.288 9.409 9.591 7.953 8.117 7.786 −2.778 0.0027644 EH-domain containing 1 NEFM 1.620 1.888 2.165 0.692 0.456 −0.834 −2.776 0.0155942 neurofilament, medium polypeptide PRSSL1 0.456 2.165 1.663 0.692 −0.834 −0.834 −2.776 0.0401902 protease, serine-like 1 TLE1 8.608 7.883 8.825 6.829 7.353 6.491 −2.775 0.0161146 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) SPEN 7.884 8.523 8.791 7.184 7.319 4.887 −2.774 0.0395034 spen homolog, transcriptional regulator (Drosophila) CHERP 8.099 8.300 8.875 6.890 7.405 4.893 −2.770 0.0298022 calcium homeostasis endoplasmic reticulum protein CDK5RAP2 5.792 6.534 6.385 4.703 5.067 4.815 −2.764 0.0123060 CDK5 regulatory subunit associated protein 2 USP7 8.768 8.918 9.745 7.451 8.308 5.908 −2.763 0.0331101 ubiquitin specific peptidase 7 (herpes virus-associated) PDLIM4 12.113 12.321 11.862 11.401 10.650 9.720 −2.756 0.0329399 PDZ and LIM domain 4 MYH11 4.876 4.735 5.058 3.274 3.781 3.414 −2.754 0.0063400 myosin, heavy chain 11, smooth muscle FOXL1 2.817 2.625 2.085 1.166 1.166 1.166 −2.748 0.0109830 forkhead box L1 ARL8A 8.701 9.283 10.091 7.686 8.482 7.825 −2.746 0.0428733 ADP-ribosylation factor-like 8A CRY2 8.867 9.000 9.917 7.671 8.046 7.410 −2.745 0.0158007 cryptochrome 2 (photolyase- like) MAN2C1 6.411 7.206 7.636 5.235 6.184 5.422 −2.736 0.0303854 mannosidase, alpha, class 2C, member 1 SQSTM1 13.426 13.022 13.739 12.613 11.978 11.523 −2.729 0.0282954 sequestosome 1 ARFGAP3 10.145 10.364 9.371 9.020 8.697 6.758 −2.728 0.0426471 ADP-ribosylation factor GTPase activating protein 3 NCOA1 7.072 6.954 7.576 5.728 6.113 5.507 −2.726 0.0112523 nuclear receptor coactivator 1 PIK3R6 3.256 2.764 3.048 1.453 1.318 2.487 −2.723 0.0399520 phosphoinositide-3-kinase, regulatory subunit 6 SNX16 4.607 4.043 4.683 2.270 3.646 3.163 −2.722 0.0335042 sorting nexin 16 GPR176 3.914 4.758 3.933 3.576 2.490 1.751 −2.719 0.0379225 G protein-coupled receptor 176 HOXC4 3.748 3.871 2.965 2.429 2.408 1.166 −2.718 0.0315957 homeobox C4 SERPINH1 11.390 11.409 10.855 10.340 9.413 9.871 −2.717 0.0221025 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) TTYH2 4.280 3.713 3.193 1.751 3.158 1.751 −2.716 0.0416101 tweety homolog 2 (Drosophila) ACOT9 8.041 8.381 9.151 7.291 7.710 6.514 −2.715 0.0452144 acyl-CoA thioesterase 9 AMT 7.592 7.457 6.994 4.040 6.105 6.154 −2.710 0.0286713 aminomethyltransferase RPL28 12.286 12.159 13.653 10.848 10.745 11.031 −2.709 0.0129852 ribosomal protein L28 SLC17A7 6.150 5.372 4.846 4.593 4.059 3.411 −2.703 0.0407144 solute carrier family 17 (sodium- dependent inorganic phosphate cotransporter), member 7 BCORL1 5.611 5.508 4.787 4.075 4.254 3.336 −2.700 0.0244104 BCL6 corepressor-like 1 BLOC1S3 5.456 5.279 6.102 4.675 4.024 1.166 −2.697 0.0411940 biogenesis of lysosomal organelles complex-1, subunit 3 STK35 5.457 5.519 4.918 4.185 3.715 3.488 −2.696 0.0096902 serine/threonine kinase 35 RRP7B 5.864 5.813 4.557 4.435 3.770 3.333 −2.692 0.0322190 ribosomal RNA processing 7 homolog B (S. cerevisiae) ANKH 8.942 8.882 8.522 7.593 7.094 7.226 −2.691 0.0055760 ankylosis, progressive homolog (mouse) CCDC59 8.794 9.004 8.643 8.283 6.620 7.366 −2.689 0.0428846 coiled-coil domain containing 59 RPS16 14.251 13.656 13.118 12.827 12.487 11.399 −2.683 0.0456479 ribosomal protein S16 NLGN2 9.493 8.658 8.950 8.070 7.854 7.002 −2.683 0.0295216 neuroligin 2 CAMSAP1 6.709 6.388 6.624 5.902 5.058 4.968 −2.676 0.0268249 calmodulin regulated spectrin- associated protein 1 LUC7L3 9.348 9.871 9.261 8.163 6.082 8.451 −2.676 0.0331865 LUC7-like 3 (S. cerevisiae) MXRA5 6.744 5.593 5.792 4.375 4.722 4.335 −2.671 0.0149013 matrix-remodelling associated 5 FAM198A 3.458 4.100 3.234 2.144 2.685 1.751 −2.668 0.0241131 family with sequence similarity 198, member A TFAP2E 3.935 3.346 3.158 2.866 1.751 1.751 −2.652 0.0374762 transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) EXOSC6 5.635 6.718 5.986 5.326 4.579 3.411 −2.651 0.0370110 exosome component 6 OSBPL3 5.329 6.235 7.046 4.829 4.885 4.243 −2.651 0.0337303 oxysterol binding protein-like 3 GPR84 2.167 1.748 2.857 1.453 0.751 0.751 −2.646 0.0401698 G protein-coupled receptor 84 MMP16 5.531 4.561 4.664 4.129 3.302 2.336 −2.643 0.0331290 matrix metal lopeptidase 16 (membrane-inserted) CSDA 3.018 4.265 4.227 2.144 1.751 2.866 −2.638 0.0294020 cold shock domain protein A TNRC6A 7.436 8.000 7.347 6.515 5.178 6.603 −2.633 0.0340843 trinucleotide repeat containing 6A SNX29 7.151 7.300 5.927 5.906 5.061 5.154 −2.628 0.0427583 sorting nexin 29 ZFC3H1 8.035 7.796 7.746 6.847 6.404 5.857 −2.626 0.0115851 zinc finger, C3H1-type containing CAMK2A 3.635 4.224 2.943 2.317 2.244 1.974 −2.622 0.0240004 calcium/calmodulin-dependent protein kinase II alpha ANGPTL2 7.695 8.225 8.775 6.835 7.085 6.579 −2.622 0.0205269 angiopoietin-like 2 ZCCHC14 6.680 6.520 6.012 5.291 5.190 4.335 −2.617 0.0188544 zinc finger, CCHC domain containing 14 LMF2 8.300 7.490 7.959 6.272 6.913 6.503 −2.615 0.0185896 lipase maturation factor 2 KIF1B 8.089 8.085 8.568 6.698 6.981 7.083 −2.615 0.0098642 kinesin family member 1B CHD2 10.537 10.348 10.587 9.150 9.263 7.348 −2.614 0.0202477 chromodomain helicase DNA binding protein 2 SNCAIP 4.518 4.796 4.585 2.144 3.315 3.411 −2.611 0.0134792 synuclein, alpha interacting protein FERMT3 3.239 3.785 4.007 2.166 2.624 2.166 −2.608 0.0157727 fermitin family member 3 KDELC2 6.353 5.925 5.974 4.593 5.099 3.411 −2.603 0.0201146 KDEL (Lys-Asp-Glu-Leu) containing 2 PI4KB 8.511 8.896 8.570 7.772 7.145 7.131 −2.603 0.0150753 phosphatidylinositol 4-kinase, catalytic, beta ABCC1 6.082 5.129 7.168 4.775 4.831 3.751 −2.600 0.0431002 ATP-binding cassette, sub- family C (CFTR/MRP), member 1 DOCK7 6.337 6.092 5.242 4.592 4.805 4.714 −2.598 0.0393234 dedicator of cytokinesis 7 CBFA2T2 7.247 7.043 6.378 5.581 5.873 5.290 −2.591 0.0232598 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 LOC221710 6.710 6.143 6.513 5.751 4.920 4.779 −2.574 0.0281623 No description MAD2L2 6.556 6.554 6.312 5.903 4.996 4.949 −2.572 0.0356131 MAD2 mitotic arrest deficient- like 2 (yeast) KIAA1026 10.055 9.720 8.667 8.693 7.507 7.555 −2.572 0.0371010 No description LOC642361 3.474 4.148 3.986 1.166 2.965 2.625 −2.568 0.0348620 No description RBM44 2.946 2.174 2.619 1.588 1.484 0.166 −2.565 0.0343635 RNA binding motif protein 44 SCARF2 4.677 4.329 4.018 3.482 2.971 2.166 −2.563 0.0258385 scavenger receptor class F, member 2 GFRA2 4.465 4.057 3.729 3.111 3.065 1.488 −2.555 0.0409641 GDNF family receptor alpha 2 TLE3 7.850 7.585 7.572 6.497 4.664 6.352 −2.554 0.0212939 transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) SGCD 5.959 5.301 5.392 2.867 4.397 4.610 −2.548 0.0366668 sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) ZNF703 7.624 6.466 5.908 5.132 4.567 5.208 −2.534 0.0239459 zinc finger protein 703 SERPING1 6.878 7.589 7.705 6.248 6.504 5.138 −2.532 0.0386585 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 MAP2K3 10.177 10.304 11.181 8.347 9.993 8.965 −2.531 0.0495503 mitogen-activated protein kinase kinase 3 SUN1 8.333 8.169 8.080 6.832 7.102 6.384 −2.525 0.0084747 Sad1 and UNC84 domain containing 1 HSP90AA1 11.104 10.685 13.080 9.599 10.190 9.771 −2.519 0.0443423 heat shock protein 90 kDa alpha (cytosolic), class A member 1 GTF3C4 4.204 3.761 3.117 2.453 2.871 1.751 −2.518 0.0427008 general transcription factor IIIC, polypeptide 4, 90 kDa TRAF5 3.750 4.008 4.683 3.022 3.352 1.974 −2.516 0.0472349 TNF receptor-associated factor 5 DCTN1 6.229 6.905 7.240 6.101 4.900 5.095 −2.514 0.0363922 dynactin 1 C19orf28 7.268 7.589 7.638 6.330 6.260 4.954 −2.512 0.0185049 chromosome 19 open reading frame 28 LOC349114 5.735 5.662 5.599 4.706 4.121 4.335 −2.509 0.0099104 No description VTI1A 4.259 5.050 4.874 3.922 3.552 2.166 −2.501 0.0444013 vesicle transport through interaction with t-SNAREs homolog 1A (yeast) SFT2D3 4.145 4.434 4.254 3.334 2.933 1.166 −2.499 0.0312046 SFT2 domain containing 3 CDK9 7.987 8.718 8.940 6.692 7.619 6.854 −2.498 0.0215934 cyclin-dependent kinase 9 SHROOM4 7.765 6.814 7.629 6.311 6.325 5.910 −2.494 0.0336320 shroom family member 4 SNX32 2.567 2.335 1.484 1.588 0.166 0.166 −2.493 0.0458892 sorting nexin 32 HHIP 1.318 2.343 2.069 0.751 0.751 0.751 −2.493 0.0368408 hedgehog interacting protein MIR155HG 2.069 2.666 1.615 0.751 1.318 0.751 −2.493 0.0448907 MIR155 host gene (non-protein coding) CALML6 3.256 2.069 1.318 0.751 0.751 0.751 −2.493 0.0465382 calmodulin-like 6 LRRFIP2 8.531 9.304 9.616 8.008 8.033 7.220 −2.481 0.0307946 leucine rich repeat (in FLU) interacting protein 2 PHRF1 8.193 7.858 7.895 6.648 6.886 5.648 −2.475 0.0154663 PHD and ring finger domains 1 ZBTB7A 9.188 8.873 8.533 7.693 7.566 7.230 −2.473 0.0111282 zinc finger and BTB domain containing 7A LSP1 10.022 10.396 10.259 7.969 9.277 8.958 −2.464 0.0222160 lymphocyte-specific protein 1 FAIM2 5.835 3.788 3.643 2.392 2.490 2.866 −2.459 0.0340155 Fas apoptotic inhibitory molecule 2 LRRC8A 9.458 9.524 9.029 8.445 8.164 7.218 −2.451 0.0284928 leucine rich repeat containing 8 family, member A LTBP4 8.784 9.304 8.231 7.739 7.490 7.048 −2.451 0.0278846 latent transforming growth factor beta binding protein 4 NUPL2 3.179 3.050 2.969 1.888 1.888 −0.834 −2.447 0.0370299 nucleoporin like 2 JUND 12.973 13.841 12.417 11.969 11.889 11.127 −2.444 0.0401585 jun D proto-oncogene ISG20L2 7.674 7.736 7.936 6.654 6.458 5.954 −2.432 0.0083302 interferon stimulated exonuclease gene 20 kDa-like 2 DEF6 3.661 4.209 5.581 3.231 2.928 2.750 −2.431 0.0447825 differentially expressed in FDCP 6 homolog (mouse) PLD1 6.633 6.627 6.107 5.009 4.829 5.392 −2.426 0.0112727 phospholipase D1, phosphatidylcholine-specific FAM53C 8.240 8.395 7.986 7.605 6.708 6.790 −2.424 0.0358211 family with sequence similarity 53, member C ZNF513 6.837 6.297 5.799 4.792 5.020 5.098 −2.423 0.0208347 zinc finger protein 513 FLNA 12.785 12.838 11.689 11.562 11.057 10.491 −2.422 0.0403453 filamin A, alpha DNAJB1 13.206 13.130 13.466 9.889 12.190 12.041 −2.422 0.0333340 DnaJ (Hsp40) homolog, subfamily B, member 1 AMFR 8.129 7.659 7.353 6.081 6.819 6.510 −2.416 0.0285836 autocrine motility factor receptor ANK2 4.894 6.411 5.439 4.412 4.529 3.626 −2.409 0.0484868 ankyrin 2, neuronal HAS2 3.320 3.749 4.136 2.488 2.865 2.488 −2.397 0.0341146 hyaluronan synthase 2 SCARF1 5.511 5.172 5.189 4.151 4.250 3.724 −2.397 0.0133809 scavenger receptor class F, member 1 COL15A1 6.317 6.286 6.755 5.282 5.497 4.611 −2.392 0.0214247 collagen, type XV, alpha 1 GJC1 8.881 8.682 8.242 7.628 7.542 6.851 −2.383 0.0267220 gap junction protein, gamma 1, 45 kDa TRABD 9.528 9.897 9.228 8.674 7.343 8.276 −2.381 0.0286902 TraB domain containing FKBP11 8.817 8.739 9.395 7.787 8.145 5.947 −2.378 0.0452825 FK506 binding protein 11, 19 kDa UBB 9.790 9.528 8.976 8.259 8.279 8.497 −2.376 0.0353877 ubiquitin B SLIT2 4.175 4.050 4.169 2.931 2.931 2.166 −2.368 0.0097492 slit homolog 2 (Drosophila) TBX19 7.172 6.634 6.774 5.756 5.731 5.391 −2.367 0.0146131 T-box 19 BAG3 7.396 7.441 7.255 6.188 6.198 5.786 −2.367 0.0069142 BCL2-associated athanogene 3 ESRRA 7.829 8.162 8.415 6.924 7.355 6.535 −2.359 0.0300079 estrogen-related receptor alpha CD99 10.034 10.215 10.808 8.602 9.185 9.576 −2.349 0.0393627 CD99 molecule RYBP 10.297 10.207 10.977 9.154 9.024 9.065 −2.348 0.0103340 RING1 and YY1 binding protein CSNK2A2 4.589 4.779 4.751 3.359 4.173 3.487 −2.346 0.0447492 casein kinase 2, alpha prime polypeptide ABHD5 7.293 8.260 7.676 6.153 6.063 7.044 −2.345 0.0380601 abhydrolase domain containing 5 IP6K2 9.037 8.149 8.758 7.582 7.529 7.207 −2.344 0.0281365 inositol hexakisphosphate kinase 2 KIAA0247 7.683 7.645 8.244 7.092 6.465 4.865 −2.327 0.0397250 KIAA0247 ZSWIM6 5.968 5.774 7.433 4.844 5.208 4.557 −2.325 0.0389278 zinc finger, SWIM-type containing 6 RYK 6.612 6.506 5.829 5.294 5.369 4.775 −2.317 0.0358393 RYK receptor-like tyrosine kinase RAPGEF4 4.785 5.346 5.165 4.135 3.638 3.623 −2.315 0.0147863 Rap guanine nucleotide exchange factor (GEF) 4 AXIN2 5.770 5.530 5.699 4.492 4.927 3.919 −2.309 0.0292092 axin 2 MED15 10.023 10.304 10.451 9.536 9.098 8.531 −2.307 0.0336660 mediator complex subunit 15 COLEC12 3.901 3.541 4.793 2.793 3.166 2.336 −2.305 0.0433975 collectin sub-family member 12 SAP30BP 7.459 7.756 8.341 6.623 6.599 6.256 −2.303 0.0167417 SAP30 binding protein RASSF5 3.596 4.055 4.358 2.853 2.972 2.626 −2.300 0.0236169 Ras association (RalGDS/ AF-6) domain family member 5 DCX 6.289 3.687 3.674 2.488 2.488 2.488 −2.296 0.0346222 doublecortin STX1A 7.367 6.835 6.470 6.170 5.685 4.413 −2.292 0.0495390 syntaxin 1A (brain) OSBPL5 6.645 6.302 6.646 5.450 5.865 4.479 −2.289 0.0463045 oxysterol binding protein- like 5 TSHZ2 5.115 5.240 5.687 3.423 4.565 4.052 −2.279 0.0296744 teashirt zinc finger homeobox 2 STAC 3.249 3.693 2.702 2.392 2.062 1.751 −2.277 0.0457061 SH3 and cysteine rich domain ZNFX1 9.262 9.251 10.138 8.368 8.070 8.712 −2.268 0.0440427 zinc finger, NFX1-type containing 1 LIME1 6.238 6.844 6.220 5.135 5.671 4.619 −2.254 0.0325775 Lek interacting transmembrane adaptor 1 SLC16A4 1.923 2.167 1.304 0.751 0.751 0.751 −2.253 0.0419036 solute carrier family 16, member 4 (monocarboxylic acid transporter 5) PLXNA1 8.094 8.433 7.885 7.380 6.930 5.954 −2.241 0.0366554 plexin A1 SBF1P1 8.887 8.499 8.528 7.417 7.726 5.915 −2.237 0.0328377 SET binding factor 1 pseudogene 1 RAB11FIP3 5.665 5.709 6.499 4.552 5.338 4.071 −2.236 0.0472129 RAB11 family interacting protein 3 (class II) HNRNPF 5.400 4.777 4.949 3.789 4.386 3.414 −2.235 0.0404134 heterogeneous nuclear ribonucleoprotein F C3orf19 5.018 5.221 5.520 4.181 4.364 3.556 −2.229 0.0266615 chromosome 3 open reading frame 19 TMEM176B 8.091 6.910 7.407 6.314 6.344 5.756 −2.226 0.0328264 transmembrane protein 176B TUSC4 6.686 6.169 6.455 5.302 4.465 5.756 −2.224 0.0430200 No description MAP3K14 3.769 4.161 4.437 3.010 3.416 2.626 −2.209 0.0427697 mitogen-activated protein kinase kinase kinase 14 SIRT2 2.914 3.504 2.632 1.949 2.146 1.488 −2.209 0.0403188 sirtuin 2 DZIP1L 5.769 6.442 6.296 5.299 4.852 4.978 −2.208 0.0293831 DAZ interacting protein 1- like GRN 9.756 9.812 9.355 8.575 8.427 8.674 −2.201 0.0198256 granulin MLXIP 7.878 8.190 7.713 7.050 7.060 6.442 −2.188 0.0358098 MLX interacting protein SLC4A8 1.880 2.069 1.726 0.751 0.751 0.751 −2.187 0.0092076 solute carrier family 4, sodium bicarbonate cotransporter, member 8 PVRIG 1.748 1.880 2.857 0.751 0.751 0.751 −2.187 0.0204368 poliovirus receptor related immunoglobulin domain containing KIF2C 2.410 1.880 1.880 0.751 1.318 0.751 −2.187 0.0332092 kinesin family member 2C DPYS 3.048 1.880 1.835 0.751 1.318 0.751 −2.187 0.0427266 dihydropyrimidinase C1orf35 7.076 7.355 6.929 5.270 6.238 5.948 −2.186 0.0238703 chromosome 1 open reading frame 35 C14orf73 3.455 3.144 3.565 2.567 1.484 2.335 −2.173 0.0338249 chromosome 14 open reading frame 73 SLK 7.996 7.315 7.602 6.997 6.484 6.063 −2.170 0.0476895 STE20-like kinase C5orf4 2.801 2.665 2.602 1.488 1.854 1.488 −2.165 0.0168355 chromosome 5 open reading frame 4 JMJD6 9.022 8.683 9.089 7.980 7.917 7.846 −2.151 0.0210904 jumonji domain containing 6 GNB5 6.073 5.580 5.413 4.310 4.666 4.837 −2.149 0.0354535 guanine nucleotide binding protein (G protein), beta 5 NCK2 8.782 8.681 9.058 7.680 6.178 8.096 −2.146 0.0447379 NCK adaptor protein 2 DENND5B 5.406 5.754 5.410 4.653 4.343 4.024 −2.145 0.0195299 DENN/MADD domain containing 5B ABCA9 4.514 5.269 4.878 3.787 4.160 3.414 −2.143 0.0450420 ATP-binding cassette, sub- family A (ABC1), member 9 OGFR 9.328 9.409 8.973 8.310 8.086 7.928 −2.141 0.0183302 opioid growth factor receptor RUNX1 9.188 9.435 9.640 8.340 8.677 6.843 −2.136 0.0484285 runt-related transcription factor 1 PLINS 7.999 8.381 8.441 7.291 7.539 6.666 −2.129 0.0410049 perilipin 3 HELLS 1.438 1.880 1.835 0.751 0.751 0.751 −2.119 0.0281176 helicase, lymphoid-specific PAR-SN 2.750 2.264 2.930 1.488 1.854 1.488 −2.108 0.0379452 No description NEO1 5.976 4.639 4.234 3.803 3.590 3.166 −2.097 0.0494936 neogenin 1 LOC646999 4.011 3.929 4.340 2.880 3.490 2.866 −2.090 0.0432689 No description SLC22A4 3.818 3.379 3.395 2.888 1.755 2.335 −2.085 0.0407530 solute carrier family 22 (organic cation/ergothioneine transporter), member 4 CAPN11 2.225 1.951 2.537 1.166 1.166 1.166 −2.083 0.0223536 calpain 11 FAM102A 7.972 7.989 8.539 6.941 7.480 5.822 −2.083 0.0446554 family with sequence similarity 102, member A FBXL6 5.771 5.140 5.539 4.221 4.492 4.651 −2.065 0.0370783 F-box and leucine-rich repeat protein 6 CENPT 9.005 9.097 8.894 8.028 8.052 7.844 −2.062 0.0143612 centromere protein T IFI16 9.758 10.377 10.448 9.592 8.714 8.821 −2.061 0.0473574 interferon, gamma-inducible protein 16 TRMU 6.406 5.891 5.525 4.853 4.863 4.756 −2.053 0.0329618 tRNA 5-methylaminomethyl- 2-thiouridylate methyltransferase GJC2 5.055 4.352 4.123 3.315 3.158 3.411 −2.052 0.0278960 gap junction protein, gamma 2, 47 kDa RASL12 4.759 3.499 3.737 2.702 2.702 2.866 −2.049 0.0425821 RAS-like, family 12 CHD6 4.286 4.088 3.909 3.073 3.206 3.073 −2.021 0.0227296 chromodomain helicase DNA binding protein 6 RBM9 8.618 8.225 8.433 7.687 7.419 7.046 −2.021 0.0344595 No description CNOT1 5.331 5.742 5.163 4.676 4.377 4.164 −1.999 0.0413476 CCR4-NOT transcription complex, subunit 1 TMEM35 1.748 2.270 1.639 0.751 0.751 0.751 −1.996 0.0205042 transmembrane protein 35 KCNN3 1.318 1.748 1.838 0.751 0.751 0.751 −1.996 0.0455378 potassium intermediate/ small conductance calcium- activated channel, subfamily N, member 3 UBE2R2 10.856 11.462 11.330 10.414 10.333 10.118 −1.995 0.0490057 ubiquitin-conjugating enzyme E2R 2 ZNF385A 10.370 9.921 10.280 8.926 9.114 9.442 −1.992 0.0331978 zinc finger protein 385A CYTH1 9.275 9.615 9.639 8.804 8.587 8.286 −1.984 0.0415057 cytohesin 1 CCDC113 2.928 2.789 2.264 1.949 1.488 1.488 −1.971 0.0458332 coiled-coil domain containing 113 ARHGAP20 3.711 3.679 3.220 2.737 2.488 2.488 −1.965 0.0363430 Rho GTPase activating protein 20 CAMK1D 6.840 6.588 6.725 5.871 4.524 5.825 −1.957 0.0444474 calcium/calmodulin- dependent protein kinase ID GTF2F1 6.626 6.797 6.899 5.837 6.035 5.365 −1.945 0.0352439 general transcription factor HF, polypeptide 1, 74 kDa CDON 4.009 3.898 4.200 2.974 3.244 2.974 −1.939 0.0248551 Cdon homolog (mouse) KIAA0240 4.837 4.692 4.855 3.891 4.140 3.166 −1.927 0.0487243 KIAA0240 SHB 7.307 7.487 8.084 6.470 6.823 6.546 −1.920 0.0477508 Src homology 2 domain containing adaptor protein B STX5 9.327 9.722 9.402 8.747 8.466 8.431 −1.914 0.0356872 syntaxin 5 KCNAB2 3.472 3.472 2.804 2.539 1.974 1.974 −1.910 0.0436479 potassium voltage-gated channel, shaker-related subfamily, beta member 2 EMILIN2 5.748 5.613 5.428 4.682 4.869 3.749 −1.906 0.0469111 elastin microfibril interfacer 2 PARP14 6.239 6.312 6.507 5.298 5.579 5.531 −1.904 0.0346108 poly (ADP-ribose) polymerase family, member 14 INTS6 6.593 6.475 6.500 5.571 5.734 5.539 −1.903 0.0211456 integrator complex subunit 6 REC8 6.773 6.465 7.041 5.655 5.877 5.997 −1.861 0.0484754 REC8 homolog (yeast) SCIN 2.686 2.750 2.264 1.488 1.854 1.488 −1.861 0.0416933 scinderin RBMX 1.748 1.438 1.639 0.751 0.751 0.751 −1.851 0.0320942 RNA binding motif protein, X-linked IL11 3.636 3.895 3.809 2.944 2.821 2.973 −1.822 0.0301827 interleukin 11 MEGF6 5.205 5.838 5.389 4.616 4.580 4.515 −1.753 0.0491176 multiple EGF-like-domains 6 C12orf57 11.466 11.673 11.501 10.429 10.718 10.903 −1.721 0.0470261 chromosome 12 open reading frame 57 Higher Expression in Parous WDR48 2.683 2.543 2.683 3.264 3.482 3.687 1.740 0.0453703 WD repeat domain 48 GRSF1 5.968 5.312 6.117 6.743 6.951 6.720 1.782 0.0489240 G-rich RNA sequence binding factor 1 COPS4 5.324 5.409 5.064 6.264 6.051 6.010 1.809 0.0449096 COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) SEL1L3 2.486 2.735 2.618 4.214 3.365 3.485 1.838 0.0417114 sel-1 suppressor of lin-12- like 3 (C. elegans) GOT2 6.305 6.283 6.226 7.742 7.191 7.031 1.876 0.0331751 glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) FAM98B 1.710 1.813 2.048 2.687 3.253 2.625 1.886 0.0417924 family with sequence similarity 98, member B GNB1 5.525 5.891 5.833 6.897 6.441 6.659 1.887 0.0432803 guanine nucleotide binding protein (G protein), beta polypeptide 1 ADPRHL1 3.113 3.378 3.004 4.029 3.891 4.434 1.887 0.0427810 ADP-ribosylhydrolase like 1 SIGMAR1 6.764 6.348 6.464 7.694 7.271 7.576 1.905 0.0329210 sigma non-opioid intracellular receptor 1 GEN1 3.294 3.019 2.989 4.185 4.014 3.920 1.907 0.0282243 Gen homolog 1, endonuclease (Drosophila) FAM104A 5.801 5.931 6.059 6.886 6.680 7.000 1.921 0.0290269 family with sequence similarity 104, member A SLC35A1 3.555 3.411 3.732 4.497 4.515 4.441 1.921 0.0250132 solute carrier family 35 (CMP-sialic acid transporter), member A1 FAM122A 3.416 3.333 3.941 4.276 4.852 4.651 1.922 0.0440821 family with sequence similarity 122A CLTA 8.046 7.773 7.936 8.716 9.002 8.805 1.922 0.0286433 clathrin, light chain A ZC3H13 4.664 4.785 4.940 5.486 5.732 5.884 1.924 0.0367810 zinc finger CCCH-type containing 13 ERIS 8.894 8.546 7.959 9.513 9.489 9.769 1.955 0.0375019 ERH exoribonuclease family member 3 TBCA 8.997 9.091 8.998 9.965 10.533 9.733 1.955 0.0377266 tubulin folding cofactor A FBXO28 4.934 4.550 4.937 6.342 5.807 5.521 1.960 0.0400269 F-box protein 28 SLC39A3 5.921 6.303 5.902 7.092 6.866 7.274 1.960 0.0269610 solute carrier family 39 (zinc transporter), member 3 SUMO2 9.100 9.857 9.407 10.676 10.381 10.361 1.964 0.0430405 SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) N4BP1 5.594 5.562 5.368 6.542 6.285 6.741 1.972 0.0245586 NEDD4 binding protein 1 CAMK1 5.949 6.261 6.037 6.995 7.734 6.939 1.986 0.0329096 calcium/calmodulin- dependent protein kinase I PDCL 4.864 5.458 4.872 6.123 5.866 6.345 2.003 0.0382742 phosducin-like PDE1A 1.166 1.166 1.166 1.722 2.169 2.625 2.004 0.0495125 phosphodiesterase 1A, calmodulin-dependent RPL12 13.182 13.313 12.857 14.194 13.740 14.675 2.016 0.0462818 ribosomal protein L12 WSB2 4.780 5.366 4.876 5.706 6.103 6.378 2.018 0.0429331 WD repeat and SOCS box- containing 2 ANGEL2 2.593 2.244 2.479 3.493 3.115 3.919 2.020 0.0377470 angel homolog 2 (Drosophila) CTBP1 6.613 6.867 7.273 8.178 8.049 7.639 2.037 0.0420329 C-terminal binding protein 1 MPDZ 5.294 5.957 6.206 7.024 6.788 6.985 2.040 0.0376660 multiple PDZ domain protein SLC26A2 2.737 2.488 2.543 3.517 3.583 3.750 2.040 0.0161865 solute carrier family 26 (sulfate transporter), member 2 TMEM133 1.318 1.453 0.751 2.270 2.316 2.487 2.048 0.0209096 transmembrane protein 133 PTAR1 6.229 5.974 6.203 7.242 6.798 7.858 2.054 0.0383672 protein prenyltransferase alpha subunit repeat containing 1 DCAF6 5.576 5.417 5.161 6.615 6.608 5.977 2.054 0.0437961 DDB1 and CUL4 associated factor 6 NDUFA13 10.345 10.842 10.280 11.500 11.318 11.677 2.054 0.0359240 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 MRPS35 5.720 6.020 6.260 7.259 7.062 6.994 2.058 0.0201577 mitochondrial ribosomal protein S35 FAM48A 4.737 4.999 4.961 5.780 5.800 6.067 2.060 0.0231456 family with sequence similarity 48, member A RBM18 2.901 2.541 2.169 3.759 3.606 3.558 2.093 0.0273567 RNA binding motif protein 18 LPAR6 4.392 4.532 4.201 5.273 5.415 6.389 2.103 0.0297704 lysophosphatidic acid receptor 6 ZEB1 6.054 6.213 6.676 7.286 7.091 8.221 2.104 0.0465601 zinc finger E-box binding homeobox 1 AQP11 0.925 0.751 1.172 1.835 1.977 2.487 2.119 0.0250768 aquaporin 11 TMEM111 1.488 1.938 1.854 2.572 3.467 2.750 2.119 0.0355420 transmembrane protein 111 UNC119 6.356 6.348 6.526 7.102 7.469 7.611 2.121 0.0304974 unc-119 homolog (C. elegans) RAB9A 1.122 2.411 2.081 3.180 3.168 3.069 2.125 0.0386471 RAB9A, member RAS oncogene family MTM1 2.817 2.920 2.929 4.008 4.420 3.596 2.126 0.0295034 myotubularin 1 STAT1 5.009 4.672 5.497 6.270 6.388 5.762 2.128 0.0480957 signal transducer and activator of transcription 1, 91 kDa EPM2AIP1 5.469 4.772 4.933 6.558 5.614 6.473 2.128 0.0497455 EPM2A (laforin) interacting protein 1 LYRM2 3.881 3.805 3.938 5.140 4.895 4.971 2.129 0.0082697 LYR motif containing 2 PTPRM 2.797 2.961 3.072 3.814 4.477 4.052 2.130 0.0197281 protein tyrosine phosphatase, receptor type, M FMR1 3.238 2.751 3.197 3.845 4.434 3.866 2.135 0.0496948 fragile X mental retardation 1 DCAF17 2.821 2.309 2.237 3.162 3.879 3.919 2.140 0.0326502 DDB1 and CUL4 associated factor 17 CHP 6.539 6.233 6.705 7.253 7.641 7.957 2.146 0.0299875 No description RAP2A 3.034 3.563 3.642 4.230 4.748 4.616 2.152 0.0307243 RAP2A, member of RAS oncogene family UBE2L6 5.656 5.557 5.385 6.610 7.339 6.495 2.159 0.0202682 ubiquitin-conjugating enzyme E2L 6 RNF187 6.950 7.175 7.229 8.020 8.286 8.728 2.160 0.0179020 ring finger protein 187 THSD1P 1.453 2.069 1.639 2.270 3.183 3.163 2.164 0.0471925 No description FAM13A 4.208 4.728 4.386 5.501 5.990 5.062 2.166 0.0490495 family with sequence similarity 13, member A NSF 5.623 5.687 5.837 7.623 6.439 6.804 2.170 0.0364036 N-ethylmalelmide-sensitive factor KCNJ8 3.635 3.893 3.788 4.433 5.787 4.908 2.174 0.0412765 potassium inwardly-rectifying channel, subfamily J, member 8 BOP1 5.854 5.970 6.305 7.624 6.837 7.096 2.183 0.0319293 block of proliferation 1 RNF125 5.317 4.848 4.590 6.443 5.641 6.195 2.183 0.0370896 ring finger protein 125 DDIT4 2.685 2.485 2.504 3.142 3.819 3.748 2.194 0.0397023 DNA-damage-inducible transcript 4 ZNF84 2.896 3.239 3.105 4.143 4.233 4.373 2.194 0.0097341 zinc finger protein 84 ACAP2 4.403 4.031 4.027 5.538 5.315 4.759 2.197 0.0429217 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 KIAA2026 4.277 4.146 4.682 5.552 5.290 5.686 2.210 0.0205738 KIAA2026 ATR 3.879 4.430 4.195 5.645 5.118 5.031 2.223 0.0338060 ataxia telangiectasia and Rad3 related KIAA1429 4.561 4.798 5.170 6.040 6.000 5.713 2.223 0.0278090 KIAA1429 PPM1H 2.264 1.595 1.595 3.111 3.074 2.750 2.227 0.0269384 protein phosphatase, Mg2+/ Mn2+ dependent, 1H TTC39A 1.788 1.595 1.488 2.522 3.917 2.750 2.227 0.0301101 tetratricopeptide repeat domain 39A GDE1 7.460 7.322 7.380 8.535 7.975 8.798 2.228 0.0390927 glycerophosphodiester phosphodiesterase 1 SNRPC 4.324 4.540 4.844 5.697 7.072 5.394 2.230 0.0398234 small nuclear ribonucleoprotein polypeptide C TGDS 1.318 2.487 2.764 3.251 3.646 3.852 2.233 0.0397137 TDP-glucose 4,6- dehydratase ACO1 6.398 7.017 6.992 7.559 8.807 7.882 2.236 0.0441426 aconitase 1, soluble RPRD1A 4.860 4.975 4.717 6.476 5.610 6.022 2.238 0.0261645 regulation of nuclear pre- mRNA domain containing 1A TTC9 4.757 4.617 4.137 5.299 6.201 5.552 2.239 0.0380488 tetratricopeptide repeat domain 9 MYCBP 1.949 2.027 3.023 3.111 3.757 3.960 2.239 0.0456237 c-myc binding protein FTO 4.474 4.423 3.991 5.240 5.637 5.485 2.239 0.0185344 fat mass and obesity associated SMPD2 3.526 4.479 4.209 5.645 5.158 5.272 2.244 0.0258196 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) HLCS 0.925 1.318 1.318 1.835 2.487 2.487 2.248 0.0363173 holocarboxylase synthetase (biotin- (proprionyl-CoA- carboxylase (ATP- hydrolysing)) ligase) CCDC50 5.922 6.898 7.014 7.848 8.183 7.843 2.249 0.0270843 coiled-coil domain containing 50 PHF17 4.483 4.773 5.268 5.653 6.016 5.972 2.251 0.0430594 PHD finger protein 17 IFIT3 2.244 2.472 2.378 3.022 3.554 4.485 2.259 0.0402674 interferon-induced protein with tetratricopeptide repeats 3 AGFG1 6.922 7.565 7.628 8.793 7.970 8.806 2.263 0.0481721 ArfGAP with FG repeats 1 C18orf45 3.742 4.025 3.497 4.921 4.571 5.609 2.264 0.0299005 chromosome 18 open reading frame 45 RAB1B 6.449 6.942 6.749 7.659 8.470 7.628 2.265 0.0324308 RAB1B, member RAS oncogene family RHBDD2 5.475 5.666 5.601 6.782 7.481 6.374 2.267 0.0261456 rhomboid domain containing 2 ARCN1 7.135 6.859 7.750 8.700 8.353 8.041 2.269 0.0465269 archain 1 FAM172A 3.616 3.254 3.226 4.080 4.590 4.801 2.275 0.0302999 family with sequence similarity 172, member A NLRX1 4.907 4.379 3.872 5.554 5.570 6.047 2.282 0.0247031 NLR family member X1 DBF4B 8.778 8.168 8.436 9.185 9.629 10.654 2.287 0.0420904 DBF4 homolog B (S. cerevisiae) EIF2B2 3.591 4.647 5.037 6.232 5.666 5.813 2.291 0.0299119 eukaryotic translation initiation factor 2B. subunit 2 beta, 39 kDa THOC2 3.339 3.276 3.864 5.042 4.768 4.472 2.291 0.0182281 THO complex 2 KRTCAP2 8.442 8.457 8.133 9.329 9.634 10.796 2.291 0.0224550 keratinocyte associated protein 2 RGS19 1.949 2.750 2.921 3.956 4.010 3.333 2.306 0.0404709 regulator of G-protein signaling 19 KIAA1671 4.418 4.761 4.595 5.653 5.629 7.058 2.315 0.0288620 KIAA1671 ARMC7 1.641 1.122 1.588 2.335 2.335 3.069 2.318 0.0382969 armadillo repeat containing 7 NHLRC1 2.429 2.250 2.817 3.433 3.649 5.198 2.330 0.0356502 NHL repeat containing 1 PDE2A 3.253 3.088 3.013 3.899 4.313 5.742 2.337 0.0387258 phosphodiesterase 2A, cGMP-stimulated NAGK 6.056 5.892 6.446 6.949 7.281 7.863 2.338 0.0300730 N-acetylglucosamine kinase FAM120A 7.883 7.420 7.563 9.227 8.212 8.790 2.341 0.0458219 family with sequence similarity 120A UBE2F 4.170 4.981 4.434 5.606 6.121 5.662 2.343 0.0233022 ubiquitin-conjugating enzyme E2F (putative) CORO1B 8.130 7.887 7.508 9.359 8.470 9.321 2.343 0.0374459 coronin, actin binding protein, 1B NDFIP2 3.516 3.677 4.432 5.620 5.075 4.745 2.344 0.0369883 Nedd4 family interacting protein 2 SIKE1 2.406 2.406 2.797 3.253 4.027 3.842 2.346 0.0286244 suppressor of IKBKE 1 CORO2A 2.194 2.244 2.528 3.759 2.853 3.485 2.347 0.0496063 coronin, actin binding protein, 2A RNF160 4.209 3.580 3.905 6.425 4.815 5.084 2.354 0.0334557 No description MRPS21 4.834 4.269 4.363 5.239 6.070 5.798 2.354 0.0298816 mitochondrial ribosomal protein S21 COPS5 4.994 5.741 6.394 6.922 7.070 6.981 2.362 0.0404315 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) HSD17B13 2.821 2.244 2.568 3.680 5.970 3.485 2.364 0.0460193 hydroxysteroid (17-beta) dehydrogenase 13 LCORL 2.686 2.789 2.164 3.412 3.757 5.060 2.375 0.0355042 ligand dependent nuclear receptor corepressor-like C7orf27 6.319 5.522 5.845 7.314 6.770 7.190 2.377 0.0288839 chromosome 7 open reading frame 27 RGAG4 5.058 5.650 4.217 6.309 6.029 6.378 2.380 0.0470450 retrotransposon gag domain containing 4 PCMTD2 3.339 3.218 3.987 4.407 5.964 4.591 2.383 0.0424898 protein-L-isoaspartate (D- aspartate) O-methyltransferase domain containing 2 ESYT1 8.029 7.385 6.278 8.611 8.638 9.135 2.384 0.0328983 extended synaptotagmin-like protein 1 AFAP1L1 6.681 6.483 6.338 7.736 7.620 7.817 2.384 0.0073151 actin filament associated protein 1-like 1 UBE2Q1 6.105 6.418 5.593 7.773 7.041 6.848 2.387 0.0466161 ubiquitin-conjugating enzyme E2Q family member 1 SHC1 6.547 6.042 5.935 7.298 7.259 7.470 2.388 0.0188393 SHC (Src homology 2 domain containing) transforming protein 1 POLDIP2 7.039 6.833 6.896 7.856 8.153 8.796 2.390 0.0174020 polymerase (DNA-directed), delta interacting protein 2 ACOT13 2.299 2.166 2.668 3.250 4.687 3.556 2.390 0.0319406 acyl-CoA thioesterase 13 C1orf25 2.299 2.406 3.064 3.600 4.496 3.556 2.390 0.0358506 chromosome 1 open reading frame 25 FAM83D 2.750 2.789 3.333 4.465 4.010 4.209 2.394 0.0158846 family with sequence similarity 83, member D ACBD5 4.967 4.588 4.276 5.340 5.849 6.381 2.397 0.0365148 acyl-CoA binding domain containing 5 SMAD1 3.482 3.562 3.281 5.136 4.744 3.951 2.398 0.0461547 SMAD family member 1 NIF3L1 2.968 2.857 3.957 4.581 4.917 4.119 2.398 0.0433030 NIF3 NGG1 interacting factor 3-like 1 (S. pombe) DHDDS 2.854 2.488 2.855 3.944 5.542 3.750 2.399 0.0291411 dehydrodolichyl diphosphate synthase KLHL7 3.841 3.521 3.425 5.676 4.295 4.786 2.403 0.0385155 kelch-like 7 (Drosophila) GRLF1 5.307 6.098 4.696 6.765 6.572 6.449 2.403 0.0493869 glucocorticoid receptor DNA binding factor 1 CYTSB 1.751 1.841 1.751 2.702 3.018 3.724 2.406 0.0182765 No description PARM1 6.260 6.401 5.768 7.401 7.035 7.846 2.407 0.0238287 prostate androgen-regulated mucin-like protein 1 PIP4K2B 4.212 3.941 3.962 5.340 4.959 5.486 2.417 0.0130949 phosphatidylinositol-5- phosphate 4-kinase, type II, beta JKAMP 3.855 4.113 4.153 6.063 5.322 5.131 2.422 0.0126078 JNK1/MAPK8-associated membrane protein ST7 2.463 3.029 3.059 3.926 4.339 3.842 2.427 0.0241600 suppression of tumorigenicity 7 GPD2 4.021 3.599 4.584 5.864 4.784 5.643 2.428 0.0365473 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) ANP32E 3.351 3.542 3.679 4.825 4.072 4.994 2.432 0.0424557 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E GALNT1 4.040 3.969 4.885 5.253 6.099 5.391 2.435 0.0379565 UDP-N-acetyl-alpha-D- galactosamine:polypeptide N- acetylgalactosaminyltransferase 1 (GalNAc-T1) NHP2L1 6.800 7.462 7.929 8.748 8.982 8.259 2.438 0.0394565 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) FXC1 5.087 5.117 4.889 6.413 6.377 5.649 2.445 0.0333612 fracture callus 1 homolog (rat) SORT1 3.380 4.031 3.808 4.335 5.653 5.102 2.452 0.0433710 sortilin 1 EXOSC7 4.214 3.184 3.687 4.478 4.935 5.974 2.452 0.0448135 exosome component 7 THTPA 4.354 4.326 3.512 4.736 5.620 6.445 2.453 0.0388188 thiamine triphosphatase TCEA1 7.677 7.601 7.976 9.728 8.838 8.975 2.460 0.0143725 transcription elongation factor A (SH), 1 C11orf54 4.332 4.846 4.979 5.632 6.071 6.770 2.462 0.0230299 chromosome 11 open reading frame 54 MRPS9 4.299 5.227 4.672 5.972 6.320 5.666 2.462 0.0306494 mitochondrial ribosomal protein S9 THUMPD3 2.556 2.423 2.920 4.210 3.955 3.724 2.464 0.0102243 THUMP domain containing 3 TANK 2.423 2.318 2.658 4.475 3.513 3.724 2.464 0.0149126 TRAF family member- associated NFKB activator PECR 4.338 3.723 3.439 5.025 4.963 5.634 2.465 0.0221721 peroxisomal trans-2-enoyl- CoA reductase GFM1 4.989 5.770 6.414 7.621 6.895 7.071 2.465 0.0310321 G elongation factor, mitochondrial 1 SLC30A5 5.027 5.356 5.494 5.898 7.353 6.660 2.468 0.0394262 solute carrier family 30 (zinc transporter), member 5 CLTCL1 1.971 1.971 2.085 3.305 3.276 3.335 2.470 0.0022704 clathrin, heavy chain-like 1 CNPY2 5.469 5.590 5.793 6.947 6.778 6.911 2.477 0.0058083 canopy 2 homolog (zebrafish) C4orf32 5.033 5.636 5.216 6.223 6.526 7.184 2.480 0.0231275 chromosome 4 open reading frame 32 YWHAB 8.875 9.129 9.921 10.945 10.374 10.440 2.480 0.0336812 tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein, beta polypeptide MGAT4A 3.294 2.909 3.708 5.021 4.106 4.889 2.485 0.0257144 mannosyl (alpha-1,3-)- glycoprotein beta-1,4-N- acetylglucosaminyltransferase, isozyme A SH3BGRL2 2.603 2.999 2.708 3.332 4.333 4.022 2.485 0.0438226 SH3 domain binding glutamic acid-rich protein like 2 HIF1AN 3.248 3.522 3.376 4.705 4.192 4.837 2.487 0.0184043 hypoxia inducible factor 1, alpha subunit inhibitor OSTM1 2.749 2.608 3.458 4.573 4.774 3.487 2.489 0.0464754 osteopetrosis associated transmembrane protein 1 DIXDC1 4.024 3.711 3.986 5.031 5.222 6.083 2.496 0.0128166 DIX domain containing 1 SNX6 5.739 6.422 6.881 7.140 7.965 7.744 2.500 0.0434436 sorting nexin 6 STX17 2.961 2.841 3.039 4.130 4.477 4.285 2.503 0.0042409 syntaxin 17 PPP2R5A 6.204 6.287 6.400 7.120 7.614 9.405 2.508 0.0376547 protein phosphatase 2, regulatory subunit B′, alpha MED20 1.751 1.841 2.395 3.315 3.724 2.866 2.512 0.0243574 mediator complex subunit 20 CCM2 3.966 4.435 3.006 5.295 5.666 4.801 2.513 0.0357515 cerebral cavernous malformation 2 RAB8A 5.064 4.899 5.067 6.556 5.894 6.393 2.513 0.0133491 RAB8A, member RAS oncogene family MRPL33 8.986 9.280 9.159 10.375 10.317 11.132 2.517 0.0105790 mitochondrial ribosomal protein L33 UBQLNL 1.122 1.122 0.420 2.799 1.755 2.335 2.522 0.0248022 ubiquilin-like C21orf63 5.540 6.015 6.823 7.266 7.027 8.164 2.533 0.0496554 chromosome 21 open reading frame 63 EIF2AK1 7.827 7.998 7.140 9.323 8.562 9.173 2.541 0.0239573 eukaryotic translation initiation factor 2-alpha kinase 1 PPID 2.808 3.029 3.012 4.359 4.906 4.118 2.544 0.0071486 peptidylprolyl isomerase D FBXL17 4.880 4.629 4.493 5.315 5.980 6.826 2.550 0.0377840 F-box and leucine-rich repeat protein 17 GBPS 3.163 2.764 3.836 5.173 4.581 4.119 2.559 0.0357795 guanylate binding protein 3 C14orf119 2.289 2.289 2.960 3.647 3.849 4.285 2.564 0.0144913 chromosome 14 open reading frame 119 COX4I1 4.999 4.822 4.827 5.940 7.928 6.191 2.573 0.0259338 cytochrome c oxidase subunit IV isoform 1 IMMP1L 2.092 2.741 3.168 3.455 4.032 5.546 2.573 0.0445382 IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) TSLP 0.925 0.925 1.880 2.270 3.256 2.487 2.595 0.0306191 thymic stromal lymphopoietin NRD1 2.821 3.426 3.651 4.259 5.061 4.199 2.599 0.0435359 nardilysin (N-arginine dibasic convertase) DDRGK1 6.460 6.785 6.216 7.595 7.688 9.004 2.602 0.0230185 DDRGK domain containing 1 ZFAND2B 5.927 6.412 6.038 7.107 7.421 8.310 2.607 0.0200806 zinc finger, AN1-type domain 2B C6orf114 0.951 0.166 1.353 2.567 2.092 2.335 2.611 0.0176539 chromosome 6 open reading frame 114 C19orf70 7.743 7.653 6.903 8.109 9.038 10.256 2.611 0.0391297 chromosome 19 open reading frame 70 MUS81 6.178 6.045 5.966 7.432 6.558 7.711 2.615 0.0446123 MUS81 endonuclease homolog (S. cerevisiae) RPL39 11.104 10.768 11.561 12.491 12.678 12.476 2.616 0.0100685 ribosomal protein L39 SFRS3 7.557 7.910 8.281 9.303 9.653 9.216 2.626 0.0085382 No description NEDD4 3.686 4.151 3.264 5.546 4.497 5.465 2.629 0.0254217 neural precursor cell expressed, developmentally down-regulated 4 ATP5A1 5.235 4.357 3.809 5.205 6.455 6.349 2.632 0.0405405 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle CNRIP1 6.788 7.154 7.677 8.551 7.867 9.293 2.634 0.0448604 cannabinoid receptor interacting protein 1 UQCR10 3.566 4.446 4.282 4.785 7.467 5.679 2.634 0.0443128 ubiquinol-cytochrome c reductase, complex III subunit X TNS1 7.980 7.733 7.794 9.131 9.631 9.161 2.636 0.0048476 tensin 1 SYNJ2BP 4.019 3.707 4.140 4.718 5.431 5.540 2.639 0.0226668 synaptojanin 2 binding protein C2orf18 3.978 3.750 4.210 5.610 5.418 4.902 2.639 0.0145420 chromosome 2 open reading frame 18 C19orf77 0.751 0.925 1.081 2.487 1.977 2.487 2.651 0.0073733 chromosome 19 open reading frame 77 SPRY2 6.646 5.861 6.723 9.575 7.666 7.271 2.657 0.0457213 sprouty homolog 2 (Drosophila) POP7 4.091 4.853 4.823 6.460 5.501 5.580 2.658 0.0414119 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) CLTC 6.621 6.763 6.866 8.174 7.739 8.282 2.659 0.0090753 clathrin, heavy chain (He) RFC5 1.949 3.236 2.750 4.647 4.229 3.333 2.659 0.0468884 replication factor C (activator 1) 5, 36.5 kDa KCTD10 3.103 2.834 2.909 3.450 4.321 4.808 2.661 0.0451176 potassium channel tetramerisation domain containing 10 ZDHHC6 3.425 4.486 4.846 5.700 5.898 5.941 2.662 0.0186101 zinc finger, DHHC-type containing 6 KIAA0391 3.407 3.282 4.052 4.813 4.819 5.364 2.662 0.0151244 KIAA0391 PODXL 6.131 5.476 6.142 8.467 6.890 6.961 2.665 0.0392727 podocalyxin-like PARL 7.663 8.179 8.035 9.001 9.783 9.452 2.671 0.0109588 presenilin associated, rhomboid-like RNASEH2A 3.256 3.163 2.343 3.957 4.581 4.586 2.672 0.0187772 ribonuclease H2, subunit A GIMAP2 1.318 2.243 2.698 3.356 4.117 3.528 2.674 0.0229436 GTPase, IMAP family member 2 SNF8 7.756 8.458 7.788 9.177 9.742 9.592 2.677 0.0099520 SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) RXRA 5.333 5.136 4.354 5.775 6.310 7.234 2.678 0.0359051 retinoid X receptor, alpha PREPL 3.325 3.494 3.380 4.147 4.803 5.125 2.683 0.0217523 prolyl endopeptidase-like TOMM22 4.222 4.604 5.457 6.028 6.786 5.741 2.684 0.0370488 translocase of outer mitochondrial membrane 22 homolog (yeast) CHPT1 2.998 2.194 2.528 3.953 5.298 3.485 2.686 0.0311085 choline phosphotransferase 1 GABBR1 6.527 7.137 6.342 8.562 7.290 8.167 2.686 0.0407871 gamma-aminobutyric acid (GABA) B receptor, 1 AKT1 8.870 9.312 8.019 10.441 9.445 10.426 2.687 0.0468998 v-akt murine thymoma viral oncogene homolog 1 ESRP2 2.815 2.977 2.682 3.626 4.242 4.853 2.689 0.0221267 epithelial splicing regulatory protein 2 RAB4A 6.675 7.033 6.460 7.888 8.103 8.797 2.691 0.0113022 RAB4A. member RAS F8A1 4.876 5.164 4.637 6.605 6.066 6.214 2.693 0.0089921 oncogene family coagulation factor VIII-associated (intronic transcript) 1 TMEM184C 3.059 3.103 3.282 5.024 4.360 4.533 2.693 0.0059293 transmembrane protein 184C DARS 6.766 5.965 6.667 7.755 8.101 8.118 2.702 0.0089323 aspartyl-tRNA synthetase HSD17B10 8.062 8.200 7.609 9.574 9.360 9.498 2.706 0.0044073 hydroxysteroid (17-beta) dehydrogenase 10 ITGA1 2.299 2.166 3.010 4.016 4.448 3.556 2.710 0.0166350 integrin, alpha 1 HSBP1 5.642 6.073 6.573 7.517 7.735 7.080 2.710 0.0227107 heat shock factor binding protein 1 SERINC2 5.110 4.601 5.084 6.040 7.253 6.354 2.712 0.0145533 serine incorporator 2 CALCOCO2 6.021 6.050 7.429 7.462 8.544 7.885 2.715 0.0461275 calcium binding and coiled- coil domain 2 MRPL30 4.699 4.878 4.539 6.030 5.980 7.086 2.716 0.0107780 mitochondrial ribosomal protein L30 UTP14A 3.266 4.215 3.542 5.879 4.986 4.586 2.722 0.0317863 UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) USH1G 2.244 3.077 2.541 4.222 3.481 4.522 2.722 0.0229550 Usher syndrome 1G (autosomal recessive) CALM2 8.538 8.558 9.526 9.611 10.974 10.153 2.728 0.0486713 calmodulin 2 (phosphorylase kinase, delta) PACSIN3 3.472 3.176 2.422 4.129 3.872 4.975 2.731 0.0472704 protein kinase C and casein kinase substrate in neurons 3 ADI1 7.355 6.585 5.936 7.664 7.908 8.806 2.734 0.0382296 acireductone dioxygenase 1 TMEM9B 4.943 4.749 6.135 7.209 6.774 6.202 2.736 0.0407031 TMEM9 domain family, member B PSMB8 5.699 6.350 7.039 7.072 8.129 8.491 2.736 0.0404429 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) C13orf31 1.751 2.379 2.135 3.834 3.810 2.866 2.742 0.0225359 chromosome 13 open reading frame 31 RUVBL1 2.866 3.517 3.713 4.973 5.577 4.252 2.743 0.0229996 RuvB-like 1 (E. coli) SUB1 4.194 3.916 4.525 5.373 7.697 5.646 2.744 0.0254845 SUB1 homolog (S. cerevisiae) BRCC3 2.611 2.406 2.624 3.656 4.070 4.335 2.748 0.0062984 BRCA1/BRCA2-containing complex, subunit 3 PCYOX1 5.798 5.632 5.114 7.092 6.040 8.100 2.751 0.0460564 prenylcysteine oxidase 1 SDF2 3.895 4.488 4.416 6.375 5.356 5.409 2.752 0.0217825 stromal cell-derived factor 2 CLEC17A 1.166 1.722 1.952 3.142 2.631 3.907 2.760 0.0182508 C-type lectin domain family 17, member A MCCC2 6.942 6.111 5.894 7.607 7.097 8.407 2.761 0.0439610 methylcrotonoyl-CoA carboxylase 2 (beta) PIGY 5.608 6.214 5.548 7.013 7.521 7.362 2.761 0.0082583 phosphatidylinositol glycan anchor biosynthesis, class Y ZMAT2 3.207 4.120 4.811 5.586 6.219 5.119 2.763 0.0335594 zinc finger, matrin-type 2 C7orf70 1.620 1.983 2.424 3.495 3.890 2.969 2.764 0.0190049 chromosome 7 open reading frame 70 APOM 2.424 2.424 1.888 2.678 3.890 4.264 2.764 0.0491630 apolipoprotein M ARMC1 2.607 3.338 3.986 4.074 5.360 4.816 2.765 0.0462114 armadillo repeat containing 1 C6orf70 4.050 4.170 3.858 5.292 5.518 5.837 2.766 0.0040541 chromosome 6 open reading frame 70 PLVAP 6.904 7.917 6.715 8.876 8.186 9.100 2.771 0.0250654 plasmalemma vesicle associated protein CNOT7 5.390 5.349 6.372 7.498 6.635 7.846 2.777 0.0229731 CCR4-NOT transcription complex, subunit 7 ZSCAN2 2.802 3.790 3.776 4.278 5.128 5.331 2.781 0.0314141 zinc finger and SCAN domain containing 2 CHKB-CPT1B 1.592 1.579 0.420 2.335 2.493 3.069 2.785 0.0316070 No description SEP7 3.072 2.429 3.536 4.730 4.983 3.907 2.787 0.0251812 septin 7 CBR4 1.595 1.854 2.232 2.572 4.010 3.333 2.787 0.0346464 carbonyl reductase 4 CCDC115 5.260 4.836 4.607 6.044 6.315 8.068 2.788 0.0235564 coiled-coil domain containing 115 C14orf167 4.497 4.212 3.786 5.382 5.267 7.252 2.791 0.0315579 chromosome 14 open reading frame 167 DTWD1 2.871 2.556 2.877 3.315 4.354 4.522 2.795 0.0363695 DTW domain containing 1 COPZ1 6.733 6.648 6.190 8.338 7.677 7.697 2.803 0.0145117 coatomer protein complex, subunit zeta 1 INPP5A 5.911 5.027 5.458 7.356 6.595 6.947 2.806 0.0143915 inositol polyphosphate-5- phosphatase, 40 kDa TMEM123 3.175 3.805 3.466 5.062 4.956 4.666 2.807 0.0084111 transmembrane protein 123 SAPSOL 4.628 4.847 4.662 7.077 5.867 6.154 2.814 0.0109043 SAP30-like ATP6V1G1 5.468 5.577 4.820 7.078 6.423 6.403 2.830 0.0219739 ATPase, H+ transporting, lysosomal 13 kDa, V1 subunit G1 MAPK14 5.026 4.441 5.094 7.055 5.946 6.087 2.838 0.0204860 mitogen-activated protein kinase 14 FASN 7.665 7.067 6.361 8.322 8.581 8.934 2.857 0.0178415 fatty acid synthase SIVA1 5.636 5.529 4.451 6.631 7.151 6.564 2.858 0.0184603 SIVA1, apoptosis-inducing factor TPRKB 6.257 6.835 6.488 8.299 8.040 7.773 2.860 0.0063211 TP53RK binding protein SEC22B 6.823 6.472 6.562 8.339 7.503 8.215 2.861 0.0140246 SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) MRPS10 3.554 4.577 4.161 6.094 5.257 5.560 2.861 0.0170064 mitochondrial ribosomal protein S10 IRGM 0.751 0.751 0.751 2.270 1.318 2.487 2.866 0.0333135 immunity-related GTPase family, M ELAC1 1.299 1.166 1.166 2.687 2.484 3.596 2.869 0.0076456 elaC homolog 1 (E. coli) EXOC5 5.239 5.360 6.399 6.929 6.882 6.808 2.872 0.0431547 exocyst complex component 5 PDHX 1.166 1.813 1.493 3.015 3.581 2.625 2.872 0.0106880 pyruvate dehydrogenase complex, component X NUDCD2 5.553 5.525 5.459 6.983 7.033 8.287 2.875 0.0070420 NudC domain containing 2 C9orf78 7.366 7.321 7.192 9.014 8.167 8.848 2.881 0.0133695 chromosome 9 open reading frame 78 WRB 5.895 5.816 5.418 7.347 6.855 8.369 2.890 0.0120987 tryptophan rich basic protein ZDHHC2 1.611 2.674 2.810 3.142 4.511 4.165 2.891 0.0347235 zinc finger, DHHC-type containing 2 TUBG1 4.519 5.676 5.790 6.658 7.211 7.217 2.898 0.0148809 tubulin, gamma 1 NAA10 8.558 8.438 8.101 9.641 9.924 10.096 2.905 0.0044414 N(alpha)-acetyltransferase 10, NatA catalytic subunit LOC147804 2.404 2.833 2.758 5.258 4.302 3.333 2.915 0.0316615 No description PUS7L 2.411 2.411 1.595 3.956 3.065 5.060 2.917 0.0223763 pseudouridylate synthase 7 homolog (S. cerevisiae)-like SLC25A3 6.238 6.542 6.309 7.856 7.256 8.221 2.922 0.0148362 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 SEPX1 6.405 6.138 5.166 7.114 7.760 7.686 2.925 0.0171025 selenoprotein X, 1 DTYMK 5.100 4.345 4.896 5.827 7.162 6.445 2.926 0.0150639 deoxythymidylate kinase (thymidylate kinase) HIST2H2BE 4.292 4.451 4.508 6.984 5.007 6.001 2.928 0.0360321 histone cluster 2, H2be NECAP2 7.297 6.959 6.849 8.515 8.327 8.848 2.929 0.0049308 NECAP endocytosis associated 2 MPI 2.625 3.068 2.250 3.334 4.385 4.619 2.930 0.0307356 mannose phosphate isomerase CXorf36 4.035 4.350 3.992 5.028 5.587 6.076 2.932 0.0163741 chromosome X open reading frame 36 WDR61 3.231 2.756 4.566 4.772 5.684 4.786 2.938 0.0446010 WD repeat domain 61 CAPN12 7.314 7.445 6.975 8.690 8.533 9.477 2.944 0.0079845 calpain 12 FLJ35776 2.270 3.653 2.461 3.828 5.031 4.199 2.945 0.0361108 No description FAM136A 4.376 5.043 4.562 6.349 6.121 5.934 2.945 0.0074626 family with sequence similarity 136, member A STAM2 3.190 3.899 4.034 5.149 5.047 5.593 2.946 0.0099898 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 HCLS1 2.735 2.954 4.269 4.294 4.802 5.313 2.946 0.0440132 hematopoietic cell-specific Lyn substrate 1 FUNDC1 0.751 1.081 0.925 1.453 2.698 2.487 2.952 0.0372137 FUN14 domain containing 1 SYDE1 5.140 5.765 5.354 7.411 6.704 6.900 2.955 0.0072818 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) NCRNA00081 1.788 1.854 1.854 2.297 3.426 4.209 2.973 0.0434550 No description BLOC1S1 9.552 10.261 8.760 10.332 10.979 12.107 2.973 0.0476781 biogenesis of lysosomal organelles complex-1, subunit 1 NIPAL3 3.446 2.937 3.715 5.329 4.033 5.019 2.975 0.0327780 NIPA-like domain containing 3 SPR 4.452 4.638 3.524 5.778 6.589 5.097 2.975 0.0304414 sepiapterin reductase (7,8- dihydrobiopterin:NADP+ oxidoreductase) MGC14436 1.484 0.166 0.759 1.588 2.335 3.165 2.982 0.0408188 No description STK25 5.504 5.301 5.674 7.082 6.316 7.833 2.987 0.0208143 serine/threonine kinase 25 GHITM 3.556 3.205 4.223 5.189 5.803 4.285 2.990 0.0450238 growth hormone inducible transmembrane protein LDHB 9.284 8.535 9.660 10.101 11.005 11.243 2.996 0.0216138 lactate dehydrogenase B DCTD 5.132 4.546 5.044 6.341 6.271 6.717 3.001 0.0058831 dOMP deaminase RPAP2 3.969 4.126 3.992 4.947 5.712 5.666 3.003 0.0109157 RNA polymerase II associated protein 2 ABHD4 4.841 4.515 5.291 6.240 6.731 6.428 3.004 0.0066108 abhydrolase domain containing 4 LARP7 3.828 3.801 5.475 5.390 5.866 6.722 3.009 0.0467523 La ribonucleoprotein domain family, member 7 ENDOD1 2.051 2.317 3.382 3.432 3.970 4.975 3.016 0.0449905 endonuclease domain containing 1 CARD8 4.900 5.965 5.007 6.495 6.521 7.669 3.022 0.0265571 caspase recruitment domain family, member 8 LSM2 4.080 5.208 5.547 5.655 7.053 7.142 3.022 0.0388544 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) PIK3R1 7.920 7.207 7.637 10.409 8.071 9.234 3.023 0.0485851 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) MUT 2.264 2.632 2.750 3.861 3.991 4.786 3.026 0.0077182 methylmalonyl CoA mutase POLD2 4.950 5.614 6.267 7.212 7.044 7.545 3.028 0.0136154 polymerase (DNA directed), delta 2, regulatory subunit 50 kDa GOLGA5 4.012 3.921 4.038 5.926 4.933 5.611 3.030 0.0108377 golgin A5 ZNF512 4.322 4.270 4.173 5.869 5.639 6.666 3.031 0.0046736 zinc finger protein 512 NAALADL1 3.877 3.400 3.049 4.999 4.137 6.141 3.031 0.0371396 N-acetylated alpha-linked acidic dipeptidase-like 1 SNRPD1 0.751 1.563 1.962 3.387 3.128 3.163 3.032 0.0066744 small nuclear ribonucleoprotein D1 polypeptide 16 kDa C6orf120 6.054 6.884 5.583 8.486 6.769 8.203 3.036 0.0411827 chromosome 6 open reading frame 120 DYNC1I2 3.284 4.040 3.987 4.898 5.985 5.004 3.060 0.0214716 dynein, cytoplasmic 1, intermediate chain 2 COX16 4.198 4.065 3.781 5.065 5.683 6.065 3.068 0.0093794 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) CLDN7 3.425 3.621 4.428 5.239 6.685 4.896 3.069 0.0273831 claudin 7 ATP5S 3.239 3.536 2.625 4.372 4.248 5.409 3.080 0.0240526 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) ZSCAN21 3.841 2.833 3.841 5.467 4.678 4.651 3.086 0.0295571 zinc finger and SCAN domain containing 21 MBNL3 1.166 1.166 1.710 2.817 1.971 3.335 3.086 0.0368219 muscleblind-like 3 (Drosophila) ROBO4 4.662 4.921 4.331 5.919 6.290 7.140 3.091 0.0081539 roundabout homolog 4, magic roundabout (Drosophila) SLC14A1 6.688 6.583 5.833 7.466 7.669 8.883 3.101 0.0248907 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) MFSD6 3.832 3.649 3.913 4.796 5.474 6.393 3.120 0.0143498 major facilitator superfamily domain containing 6 TMEM126B 2.410 2.270 2.403 3.221 4.051 5.010 3.132 0.0192863 transmembrane protein 126B DBNL 8.012 7.963 6.879 8.533 9.545 10.060 3.145 0.0239308 drebrin-like ALG3 7.055 7.257 6.799 8.911 8.098 8.781 3.147 0.0083037 asparagine-linked glycosylation 3, alpha-1,3-mannosyltransferase homolog (S. cerevisiae) C5orf22 1.420 1.166 1.710 2.429 3.075 3.748 3.149 0.0140859 chromosome 5 open reading frame 22 CDH13 3.949 5.217 5.411 6.150 6.819 7.067 3.150 0.0168998 cadherin 13, H-cadherin (heart) C1D 5.147 5.682 5.393 8.144 6.803 6.807 3.151 0.0112840 C1D nuclear receptor corepressor ADK 1.971 2.085 3.504 3.349 4.926 5.161 3.155 0.0292712 adenosine kinase RSU1 4.324 4.344 4.540 4.933 6.751 6.003 3.157 0.0381010 Ras suppressor protein 1 KIAA0649 4.454 4.479 3.231 5.750 4.892 6.627 3.161 0.0355722 KIAA0649 AKTIP 2.135 2.062 1.925 3.724 5.278 3.411 3.163 0.0103226 AKT interacting protein RNF7 6.089 6.611 6.712 8.138 7.893 8.374 3.165 0.0038529 ring finger protein 7 SH3GLB1 5.834 5.589 5.907 7.177 7.496 7.983 3.165 0.0029535 SH3-domain GRB2-like endophilin B1 FAM127B 2.409 2.926 2.343 3.678 5.118 4.072 3.166 0.0154036 family with sequence similarity 127, member B INHBB 4.093 5.539 5.737 6.142 6.750 7.401 3.168 0.0386101 inhibin, beta B PROSC 5.361 4.993 4.732 6.477 7.259 6.397 3.173 0.0075662 proline synthetase co- transcribed homolog (bacterial) CCDC58 1.692 1.484 2.980 3.002 4.646 3.456 3.175 0.0443824 coiled-coil domain containing 58 C5orf55 3.449 4.247 2.085 4.307 5.004 5.914 3.176 0.0436252 chromosome 5 open reading frame 55 RBX1 7.355 7.005 7.714 8.392 9.372 9.381 3.176 0.0106297 ring-box 1, E3 ubiquitin protein ligase FRMD3 1.974 1.974 1.974 3.642 4.098 2.973 3.179 0.0097084 FERM domain containing 3 RAB6A 5.056 5.117 4.657 6.728 5.405 7.498 3.185 0.0419149 RAB6A, member RAS oncogene family FAM24B 0.166 0.420 0.951 2.092 2.092 2.335 3.185 0.0042523 family with sequence similarity 24, member B PMS2L5 0.951 0.420 0.420 2.092 2.092 3.795 3.185 0.0120806 No description NUDT4 8.726 8.521 8.160 9.652 10.192 11.509 3.186 0.0136433 nudix (nucleoside diphosphate linked moiety X)-type motif 4 C8orf41 3.676 4.221 4.138 6.153 4.710 5.813 3.193 0.0251033 chromosome 8 open reading frame 41 DMRTA1 1.161 1.161 −0.834 2.837 2.837 2.165 3.195 0.0173869 DMRT-like family A1 RAB5C 6.178 6.822 6.557 8.234 8.664 7.766 3.197 0.0066335 RAB5C, member RAS oncogene family DHCR7 4.715 4.909 4.340 7.087 6.017 6.143 3.198 0.0082129 7-dehydrocholesterol reductase NUCKS1 9.526 9.521 9.568 11.248 10.321 11.212 3.206 0.0169951 nuclear casein kinase and cyclin- dependent kinase substrate 1 SRI 4.551 5.291 4.275 5.956 6.476 6.504 3.207 0.0110662 sorcin LHFP 7.308 6.751 7.082 8.170 8.764 8.991 3.208 0.0078506 lipoma HMGIC fusion partner AGTPBP1 2.735 3.161 3.962 4.895 4.754 4.843 3.209 0.0146524 ATP/GTP binding protein 1 C7orf30 2.424 3.727 4.735 4.766 6.418 5.185 3.211 0.0488234 chromosome 7 open reading frame 30 PRDX6 11.906 10.973 10.915 12.793 12.231 13.592 3.217 0.0256963 peroxiredoxin 6 PRKAB1 4.571 4.640 5.137 5.790 6.375 6.824 3.220 0.0134036 protein kinase, AMP-activated, beta 1 non-catalytic subunit NFYB 3.519 3.486 4.739 5.174 6.250 5.206 3.221 0.0283514 nuclear transcription factor Y, beta TSSC1 3.348 4.079 3.068 5.236 4.791 5.035 3.221 0.0125321 tumor suppressing subtransferable candidate 1 LOC147727 4.853 4.827 4.416 6.323 6.105 7.225 3.223 0.0060095 No description STARD3NL 6.602 7.250 6.972 8.660 7.871 9.060 3.223 0.0157394 STARD3 N-terminal like LANCL1 3.176 3.332 3.784 4.485 5.021 6.522 3.224 0.0207810 LanC lantibiotic synthetase component C-like 1 (bacterial) TMEM62 3.718 3.719 4.285 5.385 5.409 6.911 3.226 0.0108559 transmembrane protein 62 PSMG2 5.879 5.764 6.553 8.117 7.455 8.218 3.228 0.0047765 proteasome (prosome, macropain) assembly chaperone 2 C9orf95 4.665 5.121 5.552 5.857 6.812 7.474 3.229 0.0293294 chromosome 9 open reading frame 95 ANKMY1 4.134 2.702 3.234 5.633 4.059 5.827 3.232 0.0330087 ankyrin repeat and MYND domain containing 1 DDAH1 3.610 4.294 3.405 5.305 6.168 5.050 3.238 0.0121721 dimethylarginine dimethylaminohydrolase 1 LOC647979 6.930 6.847 6.499 8.951 8.543 8.111 3.242 0.0036698 No description MAPK3 8.663 8.203 6.597 8.796 9.613 10.361 3.243 0.0462500 mitogen-activated protein kinase 3 UQCRFS1 8.020 8.490 9.211 9.719 10.294 10.252 3.247 0.0189202 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 PEX14 2.973 2.901 3.361 4.673 5.462 3.919 3.250 0.0213483 peroxisomal biogenesis factor 14 LPGAT1 4.407 4.423 4.751 6.124 6.657 5.856 3.252 0.0044905 lysophosphatidylglycerol acyltransferase 1 NXNL2 3.859 3.596 4.465 5.743 5.299 5.670 3.255 0.0076154 nucleoredoxin-like 2 ISOC1 4.471 4.559 4.601 6.263 5.983 6.453 3.257 0.0015359 isochorismatase domain containing 1 ATOX1 9.713 8.951 8.201 9.905 10.375 11.743 3.259 0.0412387 ATX1 antioxidant protein 1 homolog (yeast) FBXO27 5.953 5.690 5.637 7.396 6.724 8.951 3.261 0.0228294 F-box protein 27 PEX7 3.458 1.862 2.741 3.439 4.546 5.167 3.269 0.0405874 peroxisomal biogenesis factor 7 TIGD2 0.692 1.161 0.456 3.070 2.165 2.165 3.270 0.0092984 tigger transposable element derived 2 APOBEC3B 0.692 0.456 1.161 2.165 4.310 2.165 3.270 0.0204671 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B DNASE1L1 2.551 2.795 2.455 3.444 4.372 4.508 3.277 0.0152583 deoxyribonuclease l-like 1 TMEM14B 4.554 4.771 6.299 6.056 7.713 8.012 3.279 0.0302772 transmembrane protein 14B OGFRL1 4.345 4.686 4.666 6.154 6.848 6.064 3.291 0.0033438 opioid growth factor receptor- like 1 LTF 1.751 2.144 2.832 3.030 6.694 3.864 3.294 0.0487636 lactotransferrin KLHL5 2.567 2.051 2.051 2.821 3.771 4.714 3.295 0.0390473 kelch-like 5 (Drosophila) PPIL5 3.168 3.778 4.066 5.239 4.890 6.040 3.299 0.0129126 peptidylproly isomerase (cyclophilin)-like 5 AP3S1 2.494 1.453 2.101 4.051 4.218 3.163 3.302 0.0111865 adaptor-related protein complex 3, sigma 1 subunit TTC38 3.660 2.973 2.983 4.710 4.136 6.100 3.310 0.0274724 tetratricopeptide repeat domain 38 HS3ST1 1.438 1.318 0.751 3.048 1.977 4.119 3.316 0.0243158 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 NAGPA 1.318 2.542 1.748 4.811 3.048 3.253 3.316 0.0276607 N-acetylglucosamine-1- phosphodiester alpha-N- acetylglucosaminidase Magmas 6.436 6.430 5.930 7.863 7.661 8.462 3.320 0.0050617 No description DLG3 2.973 2.735 2.051 3.890 3.784 4.714 3.324 0.0185163 discs, large homolog 3 (Drosophila) TMEM205 4.059 4.257 4.326 6.132 5.992 5.384 3.329 0.0049043 transmembrane protein 205 RPE 1.453 0.751 1.172 2.487 3.982 2.487 3.331 0.0155685 ribulose-5-phosphate-3- epimerase C18orf18 0.925 2.040 0.751 3.048 3.256 2.487 3.331 0.0167984 chromosome 18 open reading frame 18 C7orf68 0.751 0.751 0.751 1.453 3.752 2.487 3.331 0.0294285 chromosome 7 open reading frame 68 C19orf52 3.256 4.065 4.119 5.857 4.795 5.851 3.336 0.0158234 chromosome 19 open reading frame 52 DGUOK 6.055 5.944 6.461 8.200 7.516 8.093 3.338 0.0031865 deoxyguanosine kinase LYN 3.413 5.851 5.358 7.183 6.543 7.097 3.339 0.0249020 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog BLCAP 7.418 6.824 6.094 7.430 8.565 9.686 3.342 0.0428037 bladder cancer associated protein CCDC107 4.665 4.997 5.026 6.111 6.739 7.737 3.344 0.0089134 coiled-coil domain containing 107 LOC1002868 2.027 2.264 1.595 2.928 3.770 4.861 3.347 0.0183778 No description 44 NAA20 5.706 5.449 6.291 8.035 7.376 7.237 3.350 0.0074194 N(alpha)-acetyltransferase 20, NatB catalytic subunit MRPL12 7.827 9.107 7.575 9.861 9.629 9.323 3.359 0.0389974 mitochondrial ribosomal protein L12 NDRG2 7.037 7.528 6.782 7.988 9.279 8.843 3.366 0.0192356 NDRG family member 2 DDT 6.886 7.724 8.060 8.264 9.476 9.948 3.367 0.0334179 D-dopachrome tautomerase LOC440944 5.347 6.109 5.007 7.250 6.085 7.862 3.371 0.0421017 No description IDE 4.404 5.674 4.696 7.428 6.112 7.030 3.374 0.0134489 Description HOXA4 2.315 2.314 1.493 3.349 3.330 4.069 3.374 0.0152061 homeobox A4 NCKIPSD 3.653 3.275 2.797 4.552 5.822 4.742 3.375 0.0125057 NCK interacting protein with SH3 domain RAP1GDS1 4.501 4.181 2.617 5.859 4.689 6.258 3.381 0.0371955 RAP1, GTP-GDP dissociation stimulator 1 BTF3L4 4.221 4.941 5.948 6.586 6.740 6.699 3.382 0.0232311 basic transcription factor 3- like 4 HSPBAP1 3.717 4.208 3.939 5.708 4.649 5.968 3.386 0.0246918 HSPB (heat shock 27 kDa) associated protein 1 MRPL19 3.780 4.363 4.172 5.632 6.124 5.925 3.389 0.0022402 mitochondrial ribosomal protein L19 C7orf49 3.960 4.036 4.057 5.797 5.431 5.879 3.390 0.0015586 chromosome 7 open reading frame 49 POP4 4.088 4.377 4.444 5.854 5.892 6.699 3.400 0.0034376 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) MIF4GD 4.668 5.550 4.363 6.438 6.422 7.025 3.409 0.0095964 MIF4G domain containing GNGT2 0.925 2.494 1.318 2.698 3.248 3.852 3.416 0.0282523 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 PARP1 5.650 5.613 5.563 7.387 6.941 7.898 3.420 0.0034036 poly (ADP-ribose) polymerase 1 SACM1L 3.257 3.410 2.947 5.122 5.187 3.687 3.428 0.0376229 SAC1 suppressor of actin mutations 1-like (yeast) HMGN1 5.407 4.718 6.135 7.646 6.719 7.192 3.447 0.0156055 high-mobility group nucleosome binding domain 1 CCDC25 4.558 4.481 5.302 6.266 6.942 6.538 3.448 0.0051441 coiled-coil domain containing 25 NDUFA8 6.734 7.265 6.361 7.978 9.055 8.975 3.457 0.0082470 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19 kDa GCDH 4.818 5.771 4.659 6.452 6.577 8.469 3.465 0.0213597 glutaryl-CoA dehydrogenase OSGIN2 4.134 4.330 3.474 5.927 5.179 7.286 3.466 0.0139641 oxidative stress induced growth inhibitor family member 2 MEIS3P1 2.821 3.612 3.363 5.408 4.752 4.843 3.473 0.0055647 Meis homeobox 3 pseudogene 1 PRKRA 4.356 4.022 3.994 5.870 5.794 5.828 3.482 0.0012220 protein kinase, interferon- inducible double stranded RNA dependent activator MPDU1 2.242 2.156 2.029 3.015 4.045 4.002 3.490 0.0128937 mannose-P-dolichol utilization defect 1 MAPKAPK3 3.652 4.276 4.587 6.082 5.177 6.631 3.496 0.0158120 mitogen-activated protein kinase- activated protein kinase 3 VDAC3 3.949 4.470 4.715 6.297 6.448 5.756 3.497 0.0046925 voltage-dependent anion channel 3 FDFT1 5.926 5.470 5.903 7.914 7.614 7.276 3.497 0.0021176 farnesyl-diphosphate farnesyltransferase 1 DHRSX 4.324 4.381 4.940 6.381 6.188 6.146 3.501 0.0026797 dehydrogenase/reductase (SDR family) X-linked USHBP1 2.395 3.669 2.917 4.031 4.731 5.968 3.515 0.0243688 Usher syndrome 1C binding protein 1 EXD2 5.243 4.153 3.653 6.044 5.471 6.260 3.525 0.0302016 exonuclease 3′-5′ domain containing 2 GABARAPL2 3.347 3.809 3.570 4.489 6.358 5.390 3.530 0.0178831 GABA(A) receptor-associated protein-like 2 SLC29A2 1.938 2.164 1.595 3.506 3.416 4.317 3.532 0.0045768 solute carrier family 29 (nucleoside transporters), member 2 TYMS 3.338 2.485 1.493 4.742 3.074 5.161 3.539 0.0433597 thymidylate synthetase ARPC5 6.262 4.627 5.972 6.838 6.802 8.087 3.543 0.0441048 actin related protein 2/3 complex, subunit 5, 16 kDa C17orf37 5.112 5.446 6.094 6.939 7.802 7.347 3.549 0.0071751 chromosome 17 open reading frame 37 SERPINB6 8.629 9.321 8.273 10.101 10.594 11.064 3.551 0.0080934 serpin peptidase inhibitor, clade B (ovalbumin), member 6 IFI44 2.270 3.723 3.410 4.555 5.552 5.139 3.553 0.0115329 interferon-induced protein 44 FARS2 5.404 5.096 4.076 5.960 5.906 7.671 3.556 0.0480276 phenylalanyl-tRNA synthetase 2, mitochondrial ASMTL 4.448 4.365 4.056 6.213 5.568 6.279 3.559 0.0035957 acetylserotonin O- methyltransferase-like CASKIN2 4.917 4.965 3.108 5.175 6.797 6.727 3.560 0.0390624 CASK interacting protein 2 RUNDC2A 1.081 1.081 1.880 2.915 3.439 3.687 3.566 0.0031751 RUN domain containing 2A C14orf156 4.777 5.412 6.033 6.848 7.867 6.992 3.566 0.0125208 chromosome 14 open reading frame 156 GLRX 5.895 6.755 7.699 7.949 9.117 8.595 3.580 0.0272969 glutaredoxin (thioltransferase) LNX1 3.656 3.249 4.217 4.538 5.603 6.058 3.583 0.0229126 ligand of numb-protein X 1 NSMCE4A 1.488 1.949 2.155 3.647 4.565 3.333 3.592 0.0055533 non-SMC element 4 homolog A (S. cerevisiae) MPHOSPH6 6.606 6.101 6.087 8.007 7.256 8.451 3.593 0.0125889 M-phase phosphoprotein 6 ELTD1 7.018 9.386 8.541 10.556 9.891 10.387 3.596 0.0257878 EGF, latrophilin and seven transmembrane domain containing 1 TREX1 5.203 5.761 4.880 7.051 6.590 7.994 3.600 0.0096449 three prime repair exonuclease 1 CHCHD8 3.526 4.995 5.426 6.586 7.275 6.230 3.602 0.0165216 coiled-coil-helix-coiled-coil- helix domain containing 8 VPS25 7.548 6.352 5.701 8.784 7.481 9.397 3.602 0.0284512 vacuolar protein sorting 25 homolog (S. cerevisiae) C10orf35 2.745 2.165 1.888 4.020 3.722 5.185 3.618 0.0083922 chromosome 10 open reading frame 35 FAM89A 2.489 3.264 3.412 4.050 5.120 5.988 3.620 0.0168098 family with sequence similarity 89, member A PECAM1 5.642 5.553 6.757 7.517 7.409 7.526 3.621 0.0192659 platelet/endothelial cell adhesion molecule MORF4L1 9.630 10.185 10.430 12.465 11.094 12.043 3.625 0.0132795 mortality factor 4 like 1 COMMD8 1.299 1.299 1.493 3.159 4.724 2.625 3.630 0.0120616 COMM domain containing 8 C3orf1 6.263 5.617 6.146 7.781 7.479 8.705 3.634 0.0056131 chromosome 3 open reading frame 1 FKBP3 2.067 1.983 3.569 3.848 4.838 4.264 3.644 0.0238400 FK506 binding protein 3, 25 kDa OXCT1 1.751 2.144 2.144 2.392 4.582 4.011 3.648 0.0432371 3-oxoacid CoA transferase 1 SCCPDH 2.144 2.702 4.063 4.013 6.299 4.461 3.653 0.0464300 saccharopine dehydrogenase (putative) NEK9 4.072 5.078 4.068 6.139 6.127 5.939 3.657 0.0088264 NIMA (never in mitosis gene a)- related kinase 9 HDHD2 3.012 2.244 2.539 3.557 4.411 5.698 3.660 0.0207432 haloacid dehalogenase-like hydrolase domain containing 2 ANXA6 8.952 8.503 7.636 9.112 10.379 11.064 3.671 0.0317682 annexin A6 SNAP29 4.215 4.068 4.731 6.049 6.255 6.091 3.672 0.0019346 synaptosomal-associated protein, 29 kDa C21orf59 2.135 3.128 2.213 4.650 4.017 4.683 3.686 0.0048854 chromosome 21 open reading frame 59 GLRX3 3.624 4.041 4.445 5.934 6.330 4.966 3.693 0.0165775 glutaredoxin 3 KLF15 3.640 2.480 4.180 5.894 5.525 4.699 3.693 0.0180730 Kruppel-like factor 15 SCP2 2.675 2.804 2.853 3.514 6.545 4.693 3.706 0.0313952 sterol carrier protein 2 DCTN2 9.483 8.349 8.070 10.875 9.722 11.376 3.712 0.0175110 dynactin 2 (p50) ARHGEF16 3.142 2.085 1.611 2.817 4.385 5.035 3.714 0.0468340 Rho guanine nucleotide exchange factor (GEF) 16 H3F3C 4.804 5.125 5.118 7.012 8.091 5.351 3.717 0.0473983 H3 histone, family 3C C4orf27 1.611 3.462 3.454 3.696 5.356 5.251 3.717 0.0383173 chromosome 4 open reading frame 27 LOC148413 4.039 4.689 4.233 6.141 6.189 6.064 3.753 0.0016660 No description PECI 5.619 4.546 6.162 7.307 7.763 7.528 3.755 0.0065692 peroxisomal D3,D2-enoyl-CoA isomerase MYLK 6.970 7.804 6.564 9.336 8.223 9.713 3.756 0.0138067 myosin light chain kinase ADH5 5.157 4.484 6.771 6.399 8.161 7.409 3.769 0.0488014 alcohol dehydrogenase 5 (class III), chi polypeptide psITPTE22 0.420 1.738 0.420 2.567 2.335 3.456 3.771 0.0142492 No description APOO 3.256 2.968 1.172 5.173 4.081 3.852 3.778 0.0346827 apolipoprotein O MMEL1 3.069 3.069 1.353 3.275 4.695 6.135 3.789 0.0387780 membrane metallo-endopeptidase- like 1 AK3 4.894 4.153 4.505 5.686 6.429 7.010 3.795 0.0090548 adenylate kinase 3 HDDC2 3.783 3.368 4.027 4.428 7.665 5.710 3.803 0.0344981 HD domain containing 2 MRPL16 6.375 5.623 5.652 7.583 7.151 8.449 3.814 0.0101335 mitochondrial ribosomal protein L16 MAGOHB 3.338 3.892 3.425 5.827 4.921 5.741 3.824 0.0034187 mago-nashi homolog B (Drosophila) AP1M1 8.809 8.197 7.532 10.171 9.168 10.747 3.831 0.0198143 adaptor-related protein complex 1, mu 1 subunit COMMD7 7.016 6.693 6.310 7.862 8.631 9.793 3.832 0.0114384 COMM domain containing 7 KIAA0494 5.754 5.612 6.722 7.551 7.916 7.716 3.833 0.0091320 KIAA0494 DSTN 4.689 4.850 5.422 6.811 7.361 6.548 3.833 0.0034792 destrin (actin depolymerizing factor) CLNS1A 6.044 5.390 6.368 7.329 8.182 8.053 3.835 0.0055874 chloride channel, nucleotide- sensitive, 1A MYL12A 8.168 7.118 8.751 9.420 10.691 9.623 3.837 0.0199716 myosin, light chain 12A, regulatory, non-sarcomeric ALG5 4.080 4.104 4.896 5.660 6.837 6.108 3.841 0.0093098 asparagine-linked glycosylation 5, dolichyl-phosphate beta- glucosyltransferase homolog (S. cerevisiae) C6orf64 4.740 4.465 4.537 6.483 5.813 7.631 3.853 0.0091131 chromosome 6 open reading frame 64 C9orf119 2.069 1.748 0.751 2.698 4.190 3.528 3.854 0.0156592 chromosome 9 open reading frame 119 PIGS 6.280 6.845 5.888 8.654 6.691 8.795 3.863 0.0465934 phosphatidylinositol glycan anchor biosynthesis, class S PPAP2C 3.029 5.412 4.880 5.521 6.936 6.831 3.866 0.0377727 phosphatidic acid phosphatase type 2C EIF4EBP1 4.753 4.182 5.927 6.479 7.882 6.252 3.879 0.0289285 eukaryotic translation initiation factor 4E binding protein 1 FAM50B 5.077 4.257 3.317 5.763 5.273 8.409 3.879 0.0446910 family with sequence similarity 50, member B TPD52L1 3.841 5.024 5.321 5.350 9.026 6.983 3.888 0.0416668 tumor protein D52-like 1 PHYH 1.813 2.742 2.495 2.853 6.330 4.456 3.894 0.0435851 phytanoyl-CoA 2-hydroxylase CDKN2AIPNL 2.676 2.908 2.757 3.197 5.366 4.719 3.896 0.0399875 CDKN2A interacting protein N- terminal like ARL2BP 3.486 3.739 5.477 5.452 6.004 6.224 3.906 0.0417568 ADP-ribosylation factor-like 2 binding protein TNFRSF11B 0.166 0.166 1.122 1.122 3.091 2.335 3.913 0.0368691 tumor necrosis factor receptor superfamily, member 11b XRCC5 5.648 6.132 6.339 8.307 8.134 7.572 3.914 0.0024278 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand- break rejoining) NHP2 5.365 5.907 5.746 7.870 7.803 7.337 3.923 0.0013937 NHP2 ribonucleoprotein homolog (yeast) PCBP3 1.751 1.751 3.471 3.787 4.815 3.724 3.926 0.0324194 poly(rC) binding protein 3 FUT1 1.751 3.173 2.213 3.030 4.235 5.152 3.941 0.0431358 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) BNIP2 4.965 5.431 5.165 7.389 6.404 7.410 3.943 0.0050957 BCL2/adenovirus E1B 19 kDa interacting protein 2 EIF4EBP2 6.736 6.479 6.738 7.518 8.717 8.958 3.946 0.0135927 eukaryotic translation initiation factor 4E binding protein 2 UBL7 6.703 6.728 5.586 7.577 7.623 8.711 3.954 0.0263287 ubiquitin-like 7 (bone marrow stromal cell-derived) TOM1L1 2.787 0.951 2.567 3.180 4.603 4.551 3.957 0.0253529 target of myb1 (chicken)-like 1 MLF2 6.541 6.309 6.587 8.380 8.296 8.789 3.965 0.0008075 myeloid leukemia factor 2 RPS19BP1 6.952 6.773 4.977 8.237 7.829 8.942 3.971 0.0183930 ribosomal protein S19 binding protein 1 PDHA1 7.876 7.757 6.516 8.507 8.590 9.866 3.972 0.0400155 pyruvate dehydrogenase (lipoamide) alpha 1 TAL1 2.480 4.648 3.490 5.732 4.471 5.778 3.974 0.0426653 T-cell acute lymphocytic leukemia 1 PDCD10 1.318 2.698 1.172 4.065 4.581 3.163 3.975 0.0105117 programmed cell death 10 FLJ33630 1.488 2.623 2.027 2.928 4.616 4.117 3.981 0.0210790 No description GPT2 6.153 3.913 3.945 5.906 7.230 7.790 3.982 0.0261872 glutamic pyruvate transaminase (alanine aminotransferase) 2 PARG 3.681 2.646 3.246 5.144 4.639 5.947 3.983 0.0069331 poly (ADP-ribose) glycohydrolase APOLD1 7.998 7.643 9.597 9.639 11.569 11.240 3.988 0.0167795 apolipoprotein L domain containing 1 MAGEF1 3.797 4.328 3.578 6.524 5.204 5.798 4.004 0.0072666 melanoma antigen family F, 1 MMADHC 5.323 5.701 6.106 7.710 7.738 7.694 4.026 0.0012878 methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria GALK2 1.949 1.488 1.595 3.115 3.626 3.960 4.032 0.0026048 galactokinase 2 CRADD 3.919 1.923 1.919 3.931 4.654 5.139 4.034 0.0274353 CASP2 and RIPK1 domain containing adaptor with death domain CFL2 2.794 2.658 3.468 3.500 5.836 4.815 4.060 0.0414800 cofilin 2 (muscle) RAB4B 2.467 3.464 2.899 5.025 4.117 5.490 4.071 0.0100367 RAB4B, member RAS oncogene family C19orf12 6.238 6.426 6.714 7.372 8.620 8.740 4.072 0.0123937 chromosome 19 open reading frame 12 TNS3 3.456 4.377 4.692 4.649 6.778 6.403 4.073 0.0437697 tensin 3 ACVRL1 6.396 6.664 6.360 8.424 7.496 8.780 4.079 0.0091676 activin A receptor type II-like 1 PIGP 6.131 6.264 5.607 6.829 8.160 9.720 4.083 0.0239822 phosphatidylinositol glycan anchor biosynthesis, class P ALDH9A1 6.576 5.922 5.860 7.546 7.953 9.811 4.089 0.0126615 aldehyde dehydrogenase 9 family, member A1 CDK2AP1 6.109 5.452 6.538 7.484 8.682 7.483 4.089 0.0137107 cyclin-dependent kinase 2 associated protein 1 MAD2L1BP 5.037 3.603 3.179 6.504 4.981 7.072 4.100 0.0221380 MAD2L1 binding protein ROBLD3 7.169 7.193 6.464 7.334 9.205 9.669 4.100 0.0412273 roadblock domain containing 3 PAFAH1B3 3.643 2.503 2.165 4.539 3.495 6.550 4.101 0.0470866 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa) TMEM204 8.429 8.374 6.995 9.558 9.268 10.467 4.107 0.0209542 transmembrane protein 204 C6orf211 3.450 1.453 3.048 4.190 4.444 5.490 4.113 0.0216986 chromosome 6 open reading frame 211 C15orf24 5.416 5.811 5.486 8.010 7.240 7.528 4.118 0.0015246 chromosome 15 open reading frame 24 PFN2 4.855 3.093 4.261 5.242 6.306 6.601 4.126 0.0197394 profilin 2 NME2P1 1.122 1.641 1.862 3.424 3.168 4.189 4.130 0.0033551 non-metastatic cells 2, protein (NM23B) expressed in, pseudogene 1 SAMM50 8.468 7.856 6.788 8.399 9.909 10.564 4.150 0.0375904 sorting and assembly machinery component 50 homolog (S. cerevisiae) MRPL10 5.278 4.250 4.863 6.775 6.310 7.707 4.172 0.0064187 mitochondrial ribosomal protein L10 HOXB8 0.751 2.926 1.453 2.746 4.190 4.996 4.199 0.0271812 homeobox B8 ABLIM3 6.407 7.289 7.382 8.315 9.362 11.097 4.207 0.0133022 actin binding LIM protein family, member 3 TB01D13 3.083 3.213 2.054 4.502 4.128 5.571 4.211 0.0140745 TBC1 domain family, member 13 MCCC1 2.928 3.333 3.145 3.938 5.617 5.220 4.214 0.0170344 methylcrotonoyl-CoA carboxylase 1 (alpha) RAD21 5.319 5.288 5.484 7.563 7.545 6.768 4.223 0.0020639 RAD21 homolog (S. pombe) CD320 6.831 6.886 6.227 8.307 8.915 9.359 4.239 0.0019981 CD320 molecule DCAKD 1.611 1.166 1.299 2.045 3.696 3.596 4.241 0.0212023 dephospho-CoA kinase domain containing ISOC2 8.130 7.379 5.931 8.800 8.659 10.215 4.241 0.0282750 isochorismatase domain containing 2 METTL11A 6.955 6.761 6.666 8.846 7.672 9.085 4.242 0.0131849 methyltransferase like 11A CWF19L2 4.254 5.130 5.256 6.346 6.570 7.776 4.261 0.0104331 CWF19-like 2, cell cycle control (S. pombe) TRIM21 1.748 2.968 2.968 3.957 3.840 5.490 4.263 0.0263400 tripartite motif-containing 21 APIP 4.215 4.390 5.173 6.021 6.485 7.884 4.273 0.0102787 APAF1 interacting protein NAT6 2.092 2.567 2.946 4.016 4.672 5.208 4.301 0.0042107 N-acetyltransferase 6 (GCN5- related) FUCA1 2.745 1.880 2.857 4.853 3.840 5.883 4.310 0.0085117 fucosidase, alpha-L-1, tissue IER3IP1 3.692 3.149 3.671 5.802 5.258 5.410 4.314 0.0014762 immediate early response 3 interacting protein 1 PHGDH 4.652 4.158 5.747 5.573 8.146 6.764 4.322 0.0418703 phosphoglycerate dehydrogenase SULT2B1 2.069 0.751 0.751 3.048 2.864 3.687 4.327 0.0086918 sulfotransferase family, cytosolic, 2B, member 1 USP30 2.871 2.807 2.670 5.174 4.921 4.688 4.328 0.0004240 ubiquitin specific peptidase 30 KRT17 7.951 7.653 8.812 9.767 11.048 9.935 4.328 0.0077485 keratin 17 AASDHPPT 3.109 4.359 4.710 6.711 6.299 6.474 4.333 0.0027114 aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase AIDA 5.736 5.729 5.244 7.845 7.000 7.959 4.336 0.0027228 axin interactor, dorsalization associated SEP10 4.817 5.128 6.942 6.934 7.809 8.749 4.339 0.0245178 septin 10 ATP5J2 4.972 6.202 4.371 7.471 6.492 7.144 4.349 0.0215707 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 FAM69B 2.999 2.676 2.144 3.486 5.029 5.122 4.355 0.0159875 family with sequence similarity 69, member B ORC4L 2.572 2.994 2.716 4.840 3.693 5.428 4.359 0.0132644 No description ZSCAN16 2.741 3.131 1.898 4.866 3.168 5.546 4.363 0.0351562 zinc finger and SCAN domain containing 16 HOXA10 2.871 2.917 2.958 3.617 5.045 5.448 4.370 0.0198476 homeobox A10 CENPBD1 1.453 1.880 2.069 4.202 2.698 4.119 4.385 0.0137258 CENPB DNA-binding domains containing 1 NUDT16 4.084 5.175 3.896 6.219 5.878 8.398 4.392 0.0175775 nudix (nucleoside diphosphate linked moiety X)-type motif 16 C11orf52 0.420 2.386 1.862 2.567 3.168 6.040 4.429 0.0499815 chromosome 11 open reading frame 52 ARHGEF5L 2.745 2.614 2.424 4.766 4.128 5.901 4.445 0.0042636 No description AGL 3.110 3.885 3.210 5.364 5.081 6.047 4.452 0.0028846 amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase ALG8 0.456 −0.364 −0.364 0.692 2.614 2.165 4.464 0.0211910 asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae) LSM4 7.752 7.298 6.886 8.320 9.458 10.604 4.470 0.0164890 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) MEF2C 3.854 5.130 3.755 4.724 6.514 7.294 4.480 0.0458483 myocyte enhancer factor 2C CDC26 4.215 4.738 6.319 6.670 7.787 6.904 4.488 0.0222651 cell division cycle 26 homolog (S. cerevisiae) GRHPR 7.027 6.588 6.179 7.695 8.756 9.559 4.494 0.0117213 glyoxylate reductase/ hydroxypyruvate reductase SCGN 0.166 0.166 0.166 1.588 5.623 2.335 4.497 0.0196554 secretagogin, EF-hand calcium binding protein GPR180 4.169 3.332 3.121 5.654 5.300 6.267 4.531 0.0030912 G protein-coupled receptor 180 SCOC 1.595 1.488 1.755 3.777 4.672 3.662 4.536 0.0010011 short coiled-coil protein EXOSC1 2.542 1.453 3.455 4.065 4.835 4.726 4.545 0.0143309 exosome component 1 POLR2I 6.026 6.342 5.051 7.237 7.653 8.671 4.553 0.0114232 polymerase (RNA) II (DNA directed) polypeptide I, 14.5 kDa DCXR 10.494 10.219 7.366 12.123 10.728 12.684 4.563 0.0359467 dicarbonyl/L-xylulose reductase MRPL34 9.722 9.101 6.939 10.975 10.233 11.912 4.565 0.0231123 mitochondrial ribosomal protein L34 UIMC1 4.145 4.037 5.097 7.060 6.336 6.298 4.568 0.0035359 ubiquitin interaction motif containing 1 MTHFD2L 2.608 2.387 2.326 5.423 4.582 4.099 4.577 0.0021615 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like USMG5 3.458 4.390 5.290 6.587 9.261 5.634 4.588 0.0258082 up-regulated during skeletal muscle growth 5 homolog (mouse) CTF1 2.625 3.317 1.878 3.142 4.823 6.675 4.591 0.0442795 cardiotrophin 1 C15orf61 6.616 6.741 6.198 8.930 7.159 8.940 4.594 0.0235450 chromosome 15 open reading frame 61 ANKRD40 7.327 8.486 7.597 10.257 9.532 10.635 4.610 0.0030079 ankyrin repeat domain 40 PNPLA2 8.061 9.772 8.683 9.690 11.545 11.978 4.615 0.0244497 patatin-like phospholipase domain containing 2 RCSD1 1.318 2.060 2.445 3.527 4.148 5.050 4.623 0.0054111 RCSD domain containing 1 TKT 6.051 6.223 5.847 7.428 8.260 8.849 4.623 0.0037379 transketolase ALKBH3 0.951 2.092 1.641 2.799 3.851 4.306 4.626 0.0093551 alkB, alkylation repair homolog 3 (E. coli) SCN4A 5.747 7.271 4.567 8.088 6.778 9.065 4.632 0.0479648 sodium channel, voltage-gated, type IV, alpha subunit ADCK4 2.480 2.395 3.030 3.815 5.786 4.697 4.650 0.0106411 aarF domain containing kinase 4 DDIT4L 1.938 2.901 3.065 5.120 3.357 5.879 4.656 0.0252939 DNA-damage-inducible transcript 4-like COX7A2 2.741 2.567 4.217 4.182 6.438 6.040 4.664 0.0189051 cytochrome c oxidase subunit Vila polypeptide 2 (liver) MNAT1 6.335 6.047 5.176 7.588 7.422 8.565 4.691 0.0085496 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) HEBP2 5.777 6.263 4.558 6.797 7.678 9.362 4.720 0.0199338 heme binding protein 2 SGK1 3.691 4.861 5.079 6.505 7.783 5.933 4.730 0.0142076 serum/glucocorticoid regulated kinase 1 PJA1 6.427 6.154 4.547 8.399 6.583 8.897 4.739 0.0278203 praja ring finger 1 MPV17 2.844 2.919 2.722 3.512 5.092 5.171 4.750 0.0199603 MpV17 mitochondrial inner membrane protein C7orf41 6.387 7.171 6.769 7.229 9.070 9.423 4.762 0.0364399 chromosome 7 open reading frame 41 SNORD95 0.692 −0.364 −0.364 1.888 1.161 4.812 4.763 0.0297039 small nucleolar RNA, C/D box 95 C20orf27 7.122 7.019 5.786 8.041 9.047 10.056 4.772 0.0099331 chromosome 20 open reading frame 27 TSPAN3 5.348 5.558 4.473 6.716 8.005 7.604 4.777 0.0038945 tetraspanin 3 ETFA 2.734 4.155 5.486 5.867 7.171 6.412 4.780 0.0202069 electron-transfer-flavoprotein, alpha polypeptide FRY 5.480 6.184 5.312 7.570 7.700 8.936 4.784 0.0031290 furry homolog (Drosophila) SNX15 5.034 5.069 5.040 6.020 7.330 7.325 4.791 0.0092757 sorting nexin 15 GPI 3.073 3.550 3.120 4.702 5.386 6.273 4.811 0.0045208 glucose-6-phosphate isomerase PPP2R1B 3.798 4.967 4.385 5.106 7.994 6.652 4.814 0.0292205 protein phosphatase 2, regulatory subunit A, beta TMEM141 6.080 5.696 4.547 6.202 8.237 8.348 4.814 0.0258907 transmembrane protein 141 MANEAL 1.166 1.420 1.611 2.429 3.689 3.907 4.820 0.0090223 mannosidase, endo-alpha-like MCAM 6.625 6.902 7.270 9.372 8.896 9.252 4.827 0.0007114 melanoma cell adhesion molecule UNC50 4.573 4.066 5.088 6.512 6.338 7.565 4.828 0.0043718 unc-50 homolog (C. elegans) UBE2V2 1.488 1.938 2.264 4.099 4.538 3.960 4.837 0.0009679 ubiquitin-conjugating enzyme E2 variant 2 HNRNPD 7.054 8.188 6.985 10.059 9.466 9.262 4.848 0.0041176 heterogeneous nuclear ribonucleoprotein D (AU- rich element RNA binding protein 1, 37 kDa) C4orf3 6.933 7.219 7.224 7.720 9.497 9.567 4.850 0.0246222 chromosome 4 open reading frame 3 FAM107A 3.739 3.294 5.791 4.783 8.069 7.236 4.852 0.0492235 family with sequence similarity 107, member A MRPS7 6.717 8.347 6.917 9.197 9.104 9.500 4.858 0.0117326 mitochondrial ribosomal protein S7 RPS6KA2 5.148 5.303 5.074 7.439 6.312 7.583 4.858 0.0059784 ribosomal protein S6 kinase, 90 kDa, polypeptide 2 CHMP4A 6.608 7.038 6.468 7.379 9.108 9.319 4.860 0.0218272 chromatin modifying protein 4A NDUFS5 6.816 6.611 8.081 8.126 10.363 9.174 4.862 0.0276176 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15 kDa (NADH-coenzyme Q reductase) AOC3 4.535 5.319 4.665 5.262 7.605 7.416 4.878 0.0355306 amine oxidase, copper containing 3 (vascular adhesion protein 1) MTERFD2 4.317 4.446 3.942 6.610 5.383 8.262 4.903 0.0134603 MTERF domain containing 2 KRT16 −0.834 1.355 2.222 2.165 3.281 4.516 4.905 0.0385541 keratin 16 FERMT1 0.751 0.751 0.751 3.048 1.748 4.726 4.913 0.0170533 fermitin family member 1 PNMAL2 1.420 1.299 1.166 2.045 4.481 3.596 4.916 0.0195488 PNMA-like2 SAP18 4.876 5.000 5.527 6.275 7.368 7.826 4.919 0.0083506 Sin3A-associated protein, 18 kDa ASCC1 5.805 5.570 5.911 8.186 6.248 8.216 4.940 0.0305306 activating signal cointegrator 1 complex subunit 1 PFDN4 3.333 3.416 5.017 5.885 5.763 5.666 5.039 0.0169837 prefoldin subunit 4 LOC284551 0.420 0.420 1.122 3.164 0.951 3.456 5.041 0.0440541 No description IDO1 0.166 2.946 3.472 4.453 5.286 5.617 5.063 0.0146335 Description BNIP3L 5.287 5.093 4.645 7.477 7.440 7.416 5.087 0.0002636 BCL2/adenovirus E1B 19 kDa interacting protein 3-like BAALC 2.796 4.289 3.231 5.148 6.129 6.355 5.107 0.0045465 brain and acute leukemia, cytoplasmic CCDC12 4.067 5.576 4.992 7.344 7.350 6.911 5.108 0.0028249 coiled-coil domain containing 12 PROM1 2.878 3.966 3.642 4.233 6.310 6.319 5.109 0.0215223 prominin 1 ESAM 4.815 5.615 4.476 6.829 7.190 7.796 5.110 0.0025896 endothelial cell adhesion molecule FADS2 7.237 6.921 5.070 9.338 7.429 9.585 5.133 0.0254626 fatty acid desaturase 2 GCOM1 2.264 1.595 1.595 3.412 6.303 3.960 5.152 0.0110775 GRINL1A complex locus ZBTB8OS 2.698 3.913 4.820 5.907 6.058 7.189 5.166 0.0074384 zinc finger and BTB domain containing 8 opposite strand GNG11 4.390 5.303 4.820 6.517 9.782 7.189 5.166 0.0107515 guanine nucleotide binding protein (G protein), gamma 11 TMEM18 3.367 3.931 4.030 5.085 6.418 6.303 5.176 0.0050132 transmembrane protein 18 DUSP22 1.166 1.420 2.304 2.374 4.679 3.907 5.187 0.0261759 dual specificity phosphatase 22 RABL3 7.043 6.904 5.331 9.456 7.541 9.296 5.248 0.0174679 RAB, member of RAS oncogene family-like 3 CCDC124 6.504 6.610 6.167 8.593 8.613 9.006 5.264 0.0003748 coiled-coil domain containing 124 FADS6 1.122 1.122 0.166 3.164 2.567 5.617 5.281 0.0094414 fatty acid desaturase domain family, member 6 C10orf111 0.166 0.166 0.166 2.567 0.951 3.069 5.281 0.0163589 chromosome 10 open reading frame 111 FAM70B 4.098 6.019 4.264 6.697 6.598 6.668 5.290 0.0216532 family with sequence similarity 70, member B PEX19 3.125 2.603 3.423 4.318 6.176 5.534 5.313 0.0070125 peroxisomal biogenesis factor 19 TTRAP 0.751 0.925 3.544 3.957 4.683 3.163 5.320 0.0395185 No description SLC48A1 5.937 5.912 4.394 6.811 7.315 8.960 5.339 0.0193945 solute carrier family 48 (heme transporter), member 1 TSPAN15 2.696 3.782 2.932 5.147 5.113 6.547 5.342 0.0041789 tetraspanin 15 ANXA7 3.847 4.363 4.845 6.894 7.267 5.741 5.357 0.0053688 annexin A7 PSAT1 2.085 1.166 4.614 6.375 6.070 3.596 5.389 0.0395374 phosphoserine aminotransferase 1 MYH14 4.741 4.428 3.673 5.224 6.858 7.829 5.391 0.0169111 myosin, heavy chain 14, non- muscle ZCCHC9 2.429 3.068 3.730 5.370 5.462 6.164 5.406 0.0015132 zinc finger, CCHC domain containing 9 DPY30 3.513 3.289 4.145 5.727 6.406 6.477 5.417 0.0008756 dpy-30 homolog (C. elegans) TMEM212 7.760 8.480 6.458 8.896 9.099 11.344 5.422 0.0360208 transmembrane protein 212 ECHDC1 4.724 4.358 5.314 6.412 7.752 7.410 5.422 0.0028060 enoyl CoA hydratase domain containing 1 EIF4E3 3.503 3.679 2.896 3.586 6.365 5.943 5.425 0.0471275 eukaryotic translation initiation factor 4E family member 3 TIPIN 1.862 1.738 2.386 4.999 2.946 4.306 5.441 0.0138733 TIMELESS interacting protein DLAT 4.641 4.627 5.099 7.089 6.439 7.591 5.455 0.0018226 dihydrolipoamide S- acetyltransferase MECR 6.320 6.526 5.000 6.543 8.772 9.203 5.472 0.0327129 mitochondrial trans-2-enoyl- CoA reductase ACBD6 3.266 2.764 2.421 5.217 3.806 5.928 5.477 0.0136040 acyl-CoA binding domain containing 6 GNG2 3.810 4.051 4.822 4.851 7.276 6.776 5.481 0.0270616 guanine nucleotide binding protein (G protein), gamma 2 C9orf46 1.962 1.438 2.185 2.698 4.419 5.010 5.489 0.0168884 chromosome 9 open reading frame 46 STEAP1 8.158 7.560 7.122 10.824 8.057 10.019 5.495 0.0378642 six transmembrane epithelial antigen of the prostate 1 CIDECP 1.484 0.420 0.166 1.122 3.944 3.795 5.500 0.0349754 cell death-inducing DFFA-like effector c pseudogene ASPH 6.920 7.903 7.906 9.017 10.372 10.806 5.538 0.0053574 aspartate beta-hydroxylase HIST1H4C 1.888 0.692 1.620 4.098 3.000 7.933 5.571 0.0184157 histone cluster 1, H4c MTND6 10.305 9.937 11.250 11.159 12.785 13.954 5.580 0.0330427 No description TRIB3 2.734 3.445 1.595 7.271 5.221 3.960 5.609 0.0165662 tribbles homolog 3 (Drosophila) NDUFS8 6.262 6.432 6.672 6.823 9.621 8.926 5.631 0.0365662 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23 kDa (NADH-coenzyme Q reductase) KCTD18 3.144 3.455 3.506 5.639 5.843 6.402 5.635 0.0003226 potassium channel tetramerisation domain containing 18 NEIL2 3.193 2.423 2.967 3.842 5.689 5.484 5.641 0.0116494 nei endonuclease VIII-like 2 (E. coli) PDE6D 2.392 1.724 1.748 3.828 4.250 5.010 5.663 0.0016887 phosphodiesterase 6D, cGMP- specific, rod, delta SNAP23 3.542 3.928 5.504 6.430 6.329 6.522 5.665 0.0113635 synaptosomal-associated protein, 23 kDa PCK2 3.822 3.888 3.809 4.862 6.330 6.959 5.689 0.0096267 phosphoenolpyruvate carboxykinase 2 (mitochondrial) EFCAB3 −0.364 −0.364 0.456 2.424 0.456 2.969 5.710 0.0300877 EF-hand calcium binding domain 3 FBXO25 4.861 4.190 4.416 5.583 7.042 7.401 5.816 0.0087477 F-box protein 25 PNPLA4 2.990 3.328 2.969 4.034 5.914 5.530 5.817 0.0114989 patatin-like phospholipase domain containing 4 NDUFB10 3.315 3.346 3.460 4.878 5.887 6.635 5.819 0.0029928 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22 kDa TXNDC17 2.942 3.513 3.274 5.668 6.191 5.497 5.877 0.0004580 thioredoxin domain containing 17 MTND1 12.503 11.813 12.779 13.008 16.013 15.062 5.893 0.0254104 No description MIIP 4.825 4.782 3.266 7.319 5.835 8.198 5.935 0.0076645 migration and invasion inhibitory protein KRT5 6.326 6.556 8.156 8.904 9.676 9.295 5.970 0.0081312 keratin 5 RPUSD3 0.951 2.092 2.092 3.531 5.927 4.072 5.983 0.0068030 RNA pseudouridylate synthase domain containing 3 NQO2 1.103 1.484 0.951 2.411 3.829 4.072 6.010 0.0057160 NAD(P)H dehydrogenase, quinone 2 ZIK1 0.692 2.837 0.995 4.511 3.281 3.736 6.018 0.0137765 zinc finger protein interacting with K protein 1 homolog (mouse) CCDC69 3.719 3.752 3.840 4.358 7.019 6.354 6.070 0.0238135 coiled-coil domain containing 69 SYNPO 5.049 6.122 5.007 7.666 7.650 7.624 6.071 0.0017810 synaptopodin FLJ45244 0.925 0.925 0.925 2.270 3.632 3.528 6.073 0.0032167 No description NME4 7.103 7.103 5.968 8.421 9.715 10.442 6.111 0.0038302 non-metastatic cells 4, protein expressed in C9orf123 5.603 5.553 5.313 6.159 8.166 9.193 6.118 0.0218007 chromosome 9 open reading frame 123 TRIM5 3.334 3.448 3.898 6.066 4.374 7.156 6.141 0.0187508 tripartite motif-containing 5 PKP1 1.751 1.841 1.751 3.474 4.374 4.522 6.160 0.0012334 plakophilin 1 (ectodermal dysplasia/skin fragility syndrome) SOX10 3.783 3.072 1.493 4.120 4.146 6.561 6.179 0.0477394 SRY (sex determining region Y)- box 10 GYS1 6.665 7.067 5.503 9.364 8.180 9.296 6.195 0.0041993 glycogen synthase 1 (muscle) CYB5R3 8.103 7.814 7.105 8.903 10.446 11.254 6.197 0.0087591 cytochrome b5 reductase 3 ST6GALNAC 2.397 3.170 2.551 5.184 5.016 5.869 6.205 0.0006683 ST6 (alpha-N-acetyl-neuraminyl- 3 2,3-beta-galactosyl-1,3)-N- acetylgalactosaminide alpha- 2,6-sialyltransferase 3 RNASEH2B 2.624 2.505 3.121 4.619 5.263 5.773 6.227 0.0013211 ribonuclease H2, subunit B POLR3GL 3.269 2.817 3.452 3.874 5.929 6.521 6.318 0.0200919 polymerase (RNA) III (DNA directed) polypeptide G (32kD)- like MLX 6.659 6.993 6.203 8.864 9.075 9.857 6.327 0.0008642 MAX-like protein X MTND5 5.454 6.035 7.384 7.274 11.859 8.697 6.330 0.0353650 No description ZNF619 1.620 1.983 −0.834 4.648 1.888 3.736 6.343 0.0389709 zinc finger protein 619 PIGC 0.951 1.122 0.420 3.790 3.716 2.335 6.354 0.0029421 phosphatidylinositol glycan anchor biosynthesis, class C TUBE1 5.027 4.867 4.479 8.039 5.659 7.538 6.365 0.0141570 tubulin, epsilon 1 C10orf104 6.683 7.035 6.822 7.691 9.705 9.672 6.366 0.0135480 No description ALAD 4.192 3.997 3.636 4.459 7.162 6.668 6.371 0.0269497 aminolevulinate dehydratase LOC1001339 2.166 2.234 2.299 4.589 6.126 4.927 6.465 0.0007682 No description 20 ALKBH4 7.771 8.380 7.667 10.698 8.419 11.073 6.466 0.0297818 alkB, alkylation repair homolog 4 (E. coli) C20orf108 4.404 4.695 4.645 5.929 7.340 8.232 6.474 0.0054467 chromosome 20 open reading frame 108 NDUFAF2 2.915 4.534 4.028 7.046 6.750 5.621 6.524 0.0040654 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2 CXCL17 0.751 1.453 0.925 3.632 2.332 4.346 6.527 0.0064618 chemokine (C-X-C motif) ligand 17 ACAA2 4.465 4.032 5.187 5.681 7.874 7.898 6.549 0.0098204 acetyl-CoA acyltransferase 2 CETN2 6.936 5.514 5.607 8.324 8.124 9.715 6.572 0.0042946 centrin, EF-hand protein, 2 IGJ 3.919 7.537 6.277 9.045 8.654 8.995 6.579 0.0123680 immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides PSMG1 0.456 −0.834 0.456 1.888 3.653 2.165 6.597 0.0065995 proteasome (prosome, macropain) assembly chaperone 1 THYN1 3.632 3.163 4.065 3.847 6.516 6.790 6.610 0.0434157 thymocyte nuclear protein 1 ACSL1 4.181 4.306 5.211 5.146 7.942 7.479 6.638 0.0265685 acyl-CoA synthetase long-chain family member 1 TIMM8B 1.592 3.861 4.459 4.633 7.191 5.472 6.641 0.0369996 translocase of inner mitochondrial membrane 8 homolog B (yeast) MGC72080 1.161 2.837 2.222 4.020 5.008 4.959 6.667 0.0032356 No description SLC25A46 2.878 2.495 3.425 5.239 5.246 6.421 6.699 0.0014240 solute carrier family 25, member 46 RPS6KL1 2.756 2.789 1.949 5.538 3.581 5.525 6.725 0.0096713 ribosomal protein S6 kinase- like 1 NDUFA1 6.817 7.697 7.319 9.750 10.168 10.070 6.731 0.0003045 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5 kDa ANAPC13 4.127 4.046 5.345 5.523 8.394 6.888 6.780 0.0208793 anaphase promoting complex subunit 13 TSG101 7.826 8.501 7.724 11.262 9.473 10.674 6.781 0.0044792 tumor susceptibility gene 101 BNIP3 4.170 3.970 4.254 6.406 7.192 6.935 6.798 0.0002205 BCL2/adenovirus E1B 19 kDa interacting protein 3 AVEN 1.945 1.641 1.484 4.423 3.915 5.837 6.878 0.0014353 apoptosis, caspase activation inhibitor CHURC1 3.852 3.303 3.335 4.484 6.127 6.926 6.928 0.0121403 churchill domain containing 1 RMND5B 6.467 5.985 4.772 9.006 6.335 9.264 6.947 0.0296207 required for meiotic nuclear division 5 homolog B (S. cerevisiae) NEURL3 1.318 1.880 1.318 4.117 3.189 5.010 6.956 0.0026275 neuralized homolog 3 (Drosophila) pseudogene NUDT7 1.122 2.567 1.588 2.946 4.848 5.390 7.077 0.0107893 nudix (nucleoside diphosphate linked moiety X)-type motif 7 MCF2L 5.413 6.212 5.541 9.038 6.880 8.797 7.093 0.0080609 MCF.2 cell line derived transforming sequence-like SPHAR 1.880 0.925 1.318 2.487 4.148 5.563 7.110 0.0131297 S-phase response (cyclin related) NIPSNAP3A 2.062 2.062 2.608 3.202 5.465 5.206 7.246 0.0112243 nipsnap homolog 3A (C. elegans) HADH 3.552 3.885 4.240 4.080 8.227 6.743 7.250 0.0445601 hydroxyacyl-CoA dehydrogenase CCL13 1.318 3.323 1.748 4.607 3.646 6.361 7.255 0.0153884 chemokine (C-C motif) ligand 13 RNF14 2.567 2.541 3.245 4.783 6.106 5.673 7.264 0.0011797 ring finger protein 14 TTC1 4.576 5.390 5.655 7.148 8.257 8.839 7.294 0.0018113 tetratricopeptide repeat domain 1 FABP5 4.711 5.863 5.725 6.547 9.078 8.603 7.353 0.0107402 fatty acid binding protein 5 (psoriasis-associated) BOLA3 2.741 2.174 2.841 3.164 5.639 5.915 7.454 0.0233287 bolA homolog 3 (E. coli) HSD17B1 3.928 3.409 3.584 4.163 6.483 7.405 7.459 0.0265949 hydroxysteroid (17-beta) dehydrogenase 1 SLC9A3R2 4.099 4.407 2.964 5.440 9.603 7.012 7.534 0.0106055 solute carrier family 9 (sodium/ hydrogen exchanger), member 3 regulator 2 MRP63 3.468 3.854 4.084 6.026 6.768 8.035 7.537 0.0013438 mitochondrial ribosomal protein 63 PPARG 7.031 7.402 8.342 7.925 10.828 11.256 7.540 0.0367364 peroxisome proliferator-activated receptor gamma SUCLG2 3.450 4.452 3.921 4.065 6.837 7.481 7.551 0.0492931 succinate-CoA ligase, GDP- forming, beta subunit ATP5G3 7.285 7.239 7.397 9.932 10.361 10.208 7.584 0.0001343 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) C2orf28 4.728 4.276 4.744 5.716 7.660 7.740 7.632 0.0073582 chromosome 2 open reading frame 28 DSG2 4.028 4.227 4.584 6.114 7.183 8.945 7.763 0.0038794 desmoglein 2 LOC644538 3.978 4.421 3.591 4.700 6.944 7.882 7.814 0.0206963 No description FAIM −0.834 −0.834 1.290 1.290 4.264 2.165 7.861 0.0240998 Fas apoptotic inhibitory molecule GPN3 1.453 1.748 0.925 4.489 3.723 4.726 7.879 0.0004921 GPN-loop GTPase 3 PCYT2 2.756 2.796 2.083 3.495 5.736 6.830 7.887 0.0139104 phosphate cytidylyltransferase 2, ethanolamine UBLCP1 2.682 2.626 2.410 5.609 5.371 6.124 7.907 0.0001645 ubiquitin-like domain containing CTD phosphatase 1 HINTS 3.162 3.988 3.498 5.797 6.482 7.507 7.911 0.0011683 histidine triad nucleotide binding protein 3 MTCO3 14.380 13.260 14.195 14.444 17.366 17.355 7.927 0.0277674 No description MTCO2 11.738 11.539 11.619 12.533 16.071 14.607 7.937 0.0159535 No description ANP32A 0.951 2.174 1.484 2.799 4.482 6.198 7.987 0.0119489 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A PRDX3 8.261 7.309 6.921 10.588 9.688 11.261 7.998 0.0015700 peroxiredoxin 3 COX7B 3.828 4.190 4.879 6.767 7.886 7.268 8.039 0.0005934 cytochrome c oxidase subunit VIIb GMFG 6.858 8.027 6.202 9.211 9.611 11.172 8.047 0.0045579 glia maturation factor, gamma LPL 5.285 4.967 6.190 6.031 10.673 8.295 8.055 0.0356615 lipoprotein lipase HRCT1 2.069 2.343 2.333 2.698 5.348 7.908 8.083 0.0343211 histidine rich carboxyl terminus 1 PIR 1.318 0.925 1.318 2.746 4.365 4.346 8.156 0.0023673 pirin (iron-binding nuclear protein) NAT1 0.166 0.420 0.420 3.455 3.230 3.456 8.201 0.0001002 N-acetyltransferase 1 (arylamine N-acetyltransferase) C2orf55 0.951 0.420 0.166 1.588 3.472 4.840 8.292 0.0125624 chromosome 2 open reading frame 55 PGM1 4.564 3.728 4.192 4.277 7.977 7.253 8.345 0.0453816 phosphoglucomutase 1 PET112L 4.057 4.728 3.676 4.881 7.119 8.204 8.347 0.0216252 PET112-like (yeast) LAIR1 1.299 2.742 3.611 3.477 5.805 7.120 8.354 0.0242750 leukocyte-associated immunoglobulin-like receptor 1 SLC7A10 1.751 1.751 1.751 2.144 5.415 4.815 8.362 0.0291902 solute carrier family 7, (neutral amino acid transporter, y+ system) member 10 ECHS1 3.555 3.290 3.780 3.860 9.867 6.629 8.422 0.0428529 enoyl CoA hydratase, short chain, 1, mitochondrial TUSC5 2.336 2.336 2.336 2.336 5.414 7.021 8.442 0.0498797 tumor suppressor candidate 5 TM4SF18 5.999 6.679 4.795 9.095 6.485 10.183 8.549 0.0280170 transmembrane 4 L six family member 18 NDUFA7 5.866 3.632 4.061 4.665 8.299 8.970 8.597 0.0484399 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5 kDa KRT14 4.159 6.511 7.371 8.828 8.913 10.479 8.621 0.0071093 keratin 14 CCDC85A 3.416 3.162 3.972 3.661 7.075 7.091 8.684 0.0402561 coiled-coil domain containing 85A TST 1.710 1.166 3.334 3.696 6.460 6.460 8.729 0.0069709 thiosulfate sulfurtransferase (rhodanese) C10orf108 2.411 2.632 2.083 5.570 4.517 5.879 8.931 0.0006887 chromosome 10 open reading frame 108 TMEM42 1.748 1.453 1.880 2.270 4.986 5.050 9.002 0.0214361 transmembrane protein 42 GPIHBP1 7.800 8.849 5.199 8.393 10.809 12.542 9.154 0.0323030 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 GNAZ 4.710 6.105 5.040 7.095 8.237 10.044 9.168 0.0060828 guanine nucleotide binding protein (G protein), alpha z polypeptide HIRIP3 1.456 0.636 0.951 2.335 4.173 5.568 9.336 0.0083620 HIRA interacting protein 3 SLC22A12 −0.834 −0.834 −0.834 −0.834 2.424 2.969 9.562 0.0475295 solute carrier family 22 (organic anion/urate transporter), member 12 MDH1 7.805 8.401 7.884 10.620 11.144 12.069 9.578 0.0004467 malate dehydrogenase 1, NAD (soluble) ATP5J 5.853 6.360 7.170 8.066 10.430 9.695 9.582 0.0047992 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 IDH1 2.423 2.702 4.343 4.007 7.624 6.440 9.722 0.0236759 Description ACADS 5.652 6.452 5.495 6.858 9.452 9.737 9.751 0.0115964 acyl-CoA dehydrogenase, C-2 to C-3 short chain TXNDC9 0.166 0.166 0.420 3.455 5.036 3.069 9.773 0.0005450 thioredoxin domain containing 9 CPA1 0.166 0.166 0.166 0.166 3.802 3.456 9.779 0.0477905 carboxypeptidase A1 (pancreatic) MTND4 16.057 14.989 14.554 18.075 18.279 19.121 9.783 0.0007001 No description PLLP 1.318 3.464 3.439 4.711 5.440 6.756 9.795 0.0089626 plasmolipin C6orf203 0.420 0.951 2.861 3.770 5.843 5.617 10.196 0.0028657 chromosome 6 open reading frame 203 XRCCGBP1 0.166 0.951 1.122 2.092 4.306 5.548 10.234 0.0078045 XRCC6 binding protein 1 VTI1B 4.570 5.189 6.197 7.934 9.324 9.233 10.300 0.0009096 vesicle transport through interaction with t-SNAREs homolog 1B (yeast) METTL5 1.748 2.343 2.940 5.057 6.279 6.309 10.333 0.0004126 methyltransferase like 5 MUCL1 0.420 1.122 4.497 4.796 5.001 3.795 10.375 0.0486267 mucin-like 1 LSM3 2.752 0.951 1.353 4.145 6.891 4.775 10.715 0.0033922 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) GIMAP7 2.734 3.396 3.101 3.938 6.544 8.396 10.873 0.0178529 GTPase, IMAP family member 7 GPT 1.611 1.299 1.611 2.045 5.081 5.790 11.078 0.0219164 glutamic-pyruvate transaminase (alanine aminotransferase) RDH5 6.999 6.252 4.986 6.768 9.727 11.298 11.126 0.0261176 retinol dehydrogenase 5(11-cis/9-cis) NDUFV3 6.444 6.958 6.180 9.937 9.240 11.256 11.256 0.0006312 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10 kDa GDF5 −0.834 0.456 0.177 2.678 3.379 4.516 11.403 0.0008415 growth differentiation factor 5 NAT8L 2.919 2.603 2.610 2.793 6.140 7.701 11.550 0.0415594 N-acetyltransferase 8-like (GCN5-related, putative) C2orf84 0.166 1.738 0.636 2.620 4.173 5.711 11.611 0.0057046 chromosome 2 open reading frame 84 DBI 3.142 2.667 4.728 5.420 9.044 6.691 11.704 0.0088151 diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) LOC285550 3.252 3.614 4.017 4.496 7.590 7.168 11.746 0.0136993 No description MGST2 2.067 4.210 2.222 5.622 6.401 6.124 11.753 0.0019232 microsomal glutathione S- transferase 2 SGK2 1.166 1.166 1.299 1.166 4.758 5.865 12.054 0.0455859 serum/glucocorticoid regulated kinase 2 SNAPIN 3.256 3.801 3.957 4.949 7.552 7.454 12.090 0.0062780 SNAP-associated protein HRASLS5 1.166 1.166 1.299 1.166 4.765 6.311 12.113 0.0457871 HRAS-like suppressor family, member 5 GCSH 2.069 2.700 3.700 5.630 7.301 6.611 12.141 0.0007379 glycine cleavage system protein H (aminomethyl carrier) SLC25A10 4.721 3.729 2.921 3.757 7.654 8.348 12.355 0.0498438 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 SLC25A1 7.337 7.477 6.078 9.713 10.580 11.736 12.425 0.0009898 solute carrier family 25 (mitochondrial carrier: citrate transporter), member 1 LBP −0.834 −0.364 2.222 3.709 2.837 5.754 12.738 0.0075208 lipopolysaccharide binding protein EXOC3L −0.834 −0.834 −0.834 −0.834 2.837 2.969 12.738 0.0438956 exocyst complex component 3- like MTND2 10.503 10.437 12.690 11.970 16.371 14.616 12.828 0.0308060 No description HOXA7 0.420 1.862 0.420 3.790 5.033 5.546 12.854 0.0006048 homeobox A7 HIGD1B 2.487 3.163 1.880 2.487 6.200 7.401 13.111 0.0466910 HIG1 hypoxia inducible domain family, member 1B GCHFR 5.030 5.919 4.489 7.117 8.751 10.299 13.183 0.0037039 GTP cyclohydrolase I feedback regulator NQO1 2.593 3.800 4.317 5.708 8.626 7.670 14.619 0.0025503 NAD(P)H dehydrogenase, quinone 1 PALMD 2.234 3.330 3.799 3.742 8.087 7.211 14.735 0.0223234 palmdelphin SCD 6.163 6.195 5.317 8.368 10.520 10.060 14.895 0.0008188 stearoyl-CoA desaturase (delta- 9-desaturase) AGPAT2 7.767 7.626 6.470 7.455 11.576 12.195 15.455 0.0345669 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) C10orf58 3.245 4.783 5.619 5.722 9.992 8.751 15.648 0.0149391 chromosome 10 open reading frame 58 RGS5 4.580 6.104 6.001 6.606 10.046 10.075 15.683 0.0124686 regulator of G-protein signaling 5 HOXB7 2.069 3.085 2.487 3.847 6.872 7.167 16.939 0.0068899 homeobox B7 TM7SF2 4.883 4.838 4.382 4.734 8.950 9.971 17.297 0.0362818 transmembrane 7 superfamily member 2 LXN 2.614 4.023 2.503 7.453 6.297 8.170 17.723 0.0004013 latexin LDHD 1.166 1.166 1.166 2.045 5.334 5.410 17.975 0.0117999 lactate dehydrogenase D G0S2 3.770 6.727 7.866 8.417 10.468 12.054 18.229 0.0104557 G0/G1 switch 2 GPR109A −0.834 −0.834 0.456 0.692 3.379 4.959 18.546 0.0137576 G protein-coupled receptor 109A NDUFA12 0.166 2.494 0.636 4.658 6.492 4.889 19.067 0.0010541 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 MAOA 3.422 3.280 4.081 4.276 8.465 7.730 19.811 0.0178642 monoamine oxidase A ITGB1BP1 2.973 2.735 2.687 3.898 7.414 7.050 19.900 0.0085942 integrin beta 1 binding protein 1 CSN1S1 0.166 0.166 0.166 1.122 4.695 7.524 23.086 0.0166781 casein alpha s1 AQP7 1.949 3.162 2.789 3.412 8.905 7.343 23.499 0.0171675 aquaporin 7 HEPACAM 1.166 1.166 1.299 1.166 5.802 6.730 24.856 0.0362553 hepatocyte cell adhesion molecule AQP7P3 1.122 0.166 1.588 3.903 6.766 5.769 25.046 0.0007568 aquaporin 7 pseudogene 3 TPRG1 0.751 0.751 0.751 0.751 5.442 6.309 25.824 0.0342345 tumor protein p63 regulated 1 HSPB7 4.595 6.218 4.595 6.259 10.579 11.065 28.782 0.0110548 heat shock 27 kDa protein family, member 7 (cardiovascular) LIPE 3.932 5.260 5.385 4.724 11.661 10.199 30.681 0.0373990 lipase, hormone-sensitive ALDOC 3.661 4.861 3.676 6.909 8.652 9.882 31.479 0.0009489 aldolase C, fructose- bisphosphate GPAM 3.126 3.126 3.620 4.565 8.586 8.993 41.443 0.0072326 glycerol-3-phosphate acyltransferase, mitochondrial GPR34 0.166 0.166 0.166 0.166 5.629 7.281 44.104 0.0309561 G protein-coupled receptor 34 KCNIP2 2.973 3.246 4.269 3.126 9.783 9.470 45.679 0.0414232 Kv channel interacting protein 2 TIMP4 5.285 5.375 4.314 6.834 10.900 11.673 48.997 0.0040806 TIMP metallopeptidase inhibitor 4 CIDEC 1.166 1.166 2.810 1.722 8.950 7.069 59.834 0.0346713 cell death-inducing DFFA-like effector c GYG2 4.351 3.586 3.557 3.394 10.429 10.392 67.535 0.0393030 glycogenin 2 PLIN1 2.751 2.797 3.934 2.751 10.428 8.887 68.114 0.0423862 perilipin 1 BPIL1 −0.834 −0.834 −0.834 0.692 5.446 5.351 72.733 0.0053370 bactericidal/permeability- increasing protein-like 1 SAA1 5.835 5.597 9.372 8.690 15.271 15.700 80.310 0.0094603 serum amyloid A1 SAA2 1.488 1.488 1.595 1.488 9.062 7.851 82.297 0.0282054 serum amyloid A2 CIDEA 1.974 1.974 2.973 1.974 9.464 8.753 89.950 0.0361918 cell death-inducing DFFA- like effector a PFKFB1 0.692 −0.834 −0.834 −0.834 6.902 7.207 91.418 0.0388714 6-phosphofructo-2-kinase/ fructose-2,6-biphosphatase 1 ALDH1L1 0.751 0.751 1.318 0.751 7.646 8.378 119.008 0.0310511 aldehyde dehydrogenase 1 family, member L1 GPD1 2.853 2.626 4.079 2.626 11.086 10.658 128.615 0.0382144 glycerol-3-phosphate dehydrogenase 1 (soluble) S100B 2.423 2.334 3.158 2.392 9.741 10.449 156.537 0.0312636 S100 calcium binding protein B

To validate differences in gene expression in additional samples and by other methods, quantitative RT-PCR (qRT-PCR) analyses of selected genes were performed using CD44+ cells from multiple nulliparous and parous cases. Despite some interpersonal variability, statistically significant differences between nulliparous and parous groups were detected that overall correlated with SAGEseq data (FIG. 6 ).

To validate the parity-related gene expression differences in an independent cohort, the levels of the differentially expressed genes (in all cell types or only in CD44+ cells) were analyzed in gene expression data from breast biopsies of a cohort of Norwegian women matched to the nulliparous and parous samples for age (<40) and parity (P2). Clustering analysis using the differentially expressed gene sets divided these samples into a distinct nulliparous (Nulliparous B) and a mixed parous/nulliparous (Nulliparous A) group (FIG. 7 ). Using genes differentially expressed in all four cell types (i.e., CD24+, CD10+, CD44+ cells, and fibroblasts), combined, or only in CD44+ cells, gave identical results, supporting the hypothesis that changes in CD44+ cells are the most significant and physiologically relevant. Interestingly, the nulliparous samples that formed a distinct cluster (Nulliparous B), or were closer to parous cases (Nulliparous A), displayed significant differences in serum estradiol levels (SEL), with the samples more similar to parous cases having low SEL; all parous samples also had low SEL (FIG. 8 ). Because these were all premenopausal women and SEL is known to be higher in the luteal phase of the menstrual cycle, when breast epithelial cell proliferation is also higher, these findings implied that breast tissues of nulliparous and parous women may be more distinct in the luteal phase potentially due to differences in the activity of signaling pathways driving cell proliferation or the number of cells that respond to these stimuli.

To strengthen the hypothesis that the parity-associated differences detected in CD44+ cells might be related to subsequent breast cancer risk, the gene expression profiles of CD44+ cells from parous BRCA1 and BRCA2 mutation carriers, whose risk is not decreased by parity, were analyzed. CD44+ cells from parous BRCA1/2 mutation carriers clustered with CD44+ cells from nulliparous controls (FIG. 9A), thereby demonstrating that parity-associated changes observed in control parous women may not occur in these high risk women. The gene expression data in CD10-, CD24-, CD44+ breast epithelial cells from BRCA1 and BRCA2 mutation carriers is shown in Tables 8 and 9, below. Tables 8 and 9 show, from left column to right column, the t-value (t-score), the q-value, which is the smallest FDR (false discovery rate) at which a particular gene would just stay on the list of positives, the p-value, which is the smallest false positive rate (FPR) at which the gene appears positive, and the gene expression in P1, P2, and P3 (samples from three control tissues (CD10-, CD24-, CD44+ breast epithelial cells from parous subjects)), and in BRCA1-N105, BRCA1-N171 and BRCA1-N174 (samples from three BRCA1 mutation carriers) in Table 8 or in BRCA2-N151, BRCA2-N161 and BRCA2-N172 (samples from three BRCA2 mutation carriers). The statistical values t, p, and q are described at http://discover.nci.nih.gov/microarrayAnalysis/Statistical.Tests.jsp.

TABLE8 Differentially Expressed Genes in CD10−, CD24−, CD44+ Breast Epithelial cells of BRCA1 Mutation Carriers ID t-value q-value p-value Fold change P1 P2 P3 BRCA1-N105 BRCA-N171 BRCA1-N174 HSPA1A 2.19567994 0.043453389 0.000119088 1663.164892 2.993831 4.736586 7.997641 15.436302 17.228905 14.991147 HNRNPA1 2.118243596 0.043453389 0.000173528 672.2332477 3.024504 2.023048 2.165421 12.868252 11.558239 9.620989 LOC642361 1.969434006 0.043453389 0.000261994 578.5332207 1.874444 2.023048 2.995681 12.171937 11.778929 8.745549 ID2B 2.198930945 0.043453389 0.000112283 509.5369524 1.874444 2.023048 2.165421 11.549452 11.016091 9.303041 RPS29 1.84392888 0.043453389 0.00044573 427.4999894 4.309025 5.362142 6.282905 15.630577 14.101923 11.48514 MAGEB10 2.429149475 0.043453389 7.15E−05 422.777762 3.024504 2.023048 2.165421 10.746803 11.544714 11.312574 CENPH 2.165594943 0.043453389 0.000139503 419.9055175 4.743564 3.770995 2.165421 11.697868 12.808177 12.484916 KRT18 1.696996829 0.043453389 0.000779177 363.1762985 1.874444 3.872014 2.165421 12.37654 10.68376 8.213534 RPL27A 2.223955537 0.043453389 9.87E−05 317.7835144 5.779429 5.148082 6.670675 14.585927 14.09133 13.791736 RAD21-AS1 2.318523081 0.043453389 8.51E−05 301.3830562 1.874444 2.406905 2.165421 10.093095 11.437977 10.400875 RPLP1 2.183840284 0.043453389 0.000125893 301.1534971 6.52121 6.072636 6.527811 15.605413 14.755565 13.685741 USP33 1.918655981 0.043453389 0.000323239 290.8179694 5.982974 3.360637 3.764125 11.54461 12.544527 12.777496 AKR1D1 2.034393168 0.043453389 0.000227969 281.8516744 2.993831 3.770995 3.935222 10.369894 11.909787 12.782289 FAM83A 2.059799803 0.043453389 0.000214359 265.2498231 1.874444 2.023048 2.165421 8.723321 10.074256 10.27958 BMP3 2.291911149 0.043453389 9.19E−05 262.4866963 3.350997 3.360637 3.764125 11.047646 11.800225 11.713056 ATPIF1 1.958064245 0.043453389 0.000289214 253.5595079 3.024504 2.023048 2.379345 11.378567 10.365525 9.018932 APEX1 2.100883422 0.043453389 0.000200749 251.0765437 2.201691 2.023048 2.165421 10.608241 10.137404 9.008063 NDUFB9 2.220381039 0.043453389 0.000105478 242.6979432 3.024504 2.406905 2.165421 10.632786 10.329923 10.117111 EEF1B2 1.93003145 0.043453389 0.000302824 238.8353675 5.658609 3.872014 4.508334 13.773392 12.408206 11.469377 COX6A1 2.12160288 0.043453389 0.000166723 228.6747402 2.201691 2.023048 2.165421 11.38219 10.002574 9.363984 AZGP1  1.618309973 0.043453389 0.001044573 225.9865268 3.024504 5.43468 2.165421 13.636724 9.985514 10.157018 NGFRAP1  1.985894212 0.043453389 0.000248384 224.8691195 2.201691 2.809601 2.165421 10.283397 10.622543 8.894619 RPL5  1.961424091 0.043453389 0.000275604 219.8114179 4.682076 4.911517 6.450701 13.291304 12.849623 12.462199 F5  2.169345983 0.043453389 0.000132698 217.5426617 4.743564 4.389936 5.389265 12.155091 13.106596 13.021304 TRMT5  1.959177502 0.043453389 0.000282409 214.0595634 2.993831 2.406905 3.324375 11.841672 10.735699 9.462817 IFNG  1.839643425 0.043453389 0.000452535 210.0206014 1.874444 2.023048 2.165421 9.904384 7.870158 9.737435 MRFAP1  1.628363209 0.043453389 0.001003743 205.9092748 1.874444 2.023048 2.165421 11.655074 9.708913 7.03218 NDUFB4  1.602438669 0.043453389 0.001105818 202.805178 5.304463 2.406905 2.165421 10.207812 9.979782 10.070856 RPS15AP10  2.107597589 0.043453389 0.000187138 198.9640087 1.874444 2.406905 2.165421 10.522177 9.179013 9.801784 TMEM66  2.021922072 0.043453389 0.000234774 195.3421233 3.819732 3.770995 4.508334 12.465486 11.429592 10.913082 CRIP1  2.140409416 0.043453389 0.000153113 183.3012252 1.874444 2.023048 2.165421 9.513069 9.392516 10.769222 VKORC1  2.135818569 0.043453389 0.000159918 170.4303269 2.201691 2.023048 2.165421 9.212855 9.578459 10.233665 ANP32A-IT1  1.865657143 0.043453389 0.000411705 168.643307 2.993831 2.023048 2.165421 10.088666 10.391662 8.488368 GADD45A  1.931996026 0.043453389 0.000296019 160.2363742 2.201691 4.413323 3.324375 11.590755 10.573912 10.648433 TPT1  1.708125641 0.043453389 0.000745151 155.053927 7.317579 7.598777 8.345336 15.666962 14.875403 13.24435 COX6C  1.76102932 0.043453389 0.000636271 154.2260542 1.874444 2.023048 4.449894 11.326854 10.479583 9.143346 ORC4  1.966892101 0.043453389 0.000268799 153.869353 5.658609 6.270596 4.724406 12.49758 13.536158 12.87419 ATP5C1  1.852589825 0.043453389 0.000438925 153.8305556 2.201691 3.872014 2.165421 10.413045 9.847551 9.430619 RPL23AP32  1.809158235 0.043453389 0.00052739 153.6520772 3.819732 5.43468 5.544653 13.203909 12.609999 11.083256 PLAC9  2.10842088 0.043453389 0.000180333 150.8812505 1.874444 2.406905 2.165421 9.111713 9.570854 9.540302 LECT2  2.102414855 0.043453389 0.000193944 148.9165857 1.874444 2.023048 2.165421 9.137671 9.866312 9.092804 FOS  1.885638086 0.043453389 0.000377679 143.7517704 7.906175 8.359538 9.485302 15.43434 15.772014 15.526973 SHFM1  2.043479395 0.043453389 0.000221164 141.4833514 1.874444 2.406905 2.165421 10.061802 9.294336 9.018932 ERH  1.8936896 0.043453389 0.000357264 140.8997425 2.993831 2.023048 2.165421 10.132356 9.615895 8.705744 GAS5  1.923211748 0.043453389 0.000316434 140.7527401 5.263699 4.830496 5.723602 13.152318 12.400718 11.714728 SEC61B  1.892002869 0.043453389 0.000364069 139.6464222 1.874444 2.023048 2.165421 9.359771 9.148683 8.11568 SH3BGRL  1.913051187 0.043453389 0.000330044 139.3348421 2.993831 3.770995 3.90836 12.125128 10.893407 10.033825 RPL22L1  1.508761265 0.043453389 0.001534536 137.5242179 3.024504 2.023048 2.165421 10.128046 9.303543 6.942983 COX5B  1.705369901 0.043453389 0.000751956 134.1276716 4.209882 2.406905 2.379345 9.615142 9.563208 9.446808 KLHDC2  2.065680981 0.043453389 0.000207554 133.7125125 1.874444 2.023048 2.165421 9.299725 9.086038 8.771488 MAGED1  1.222033132 0.043453389 0.005155495 132.7235295 1.874444 2.023048 2.165421 9.698891 9.075328 4.790662 PNN  1.557414287 0.043453389 0.001269139 131.9970759 3.024504 2.023048 3.764125 10.906311 10.068866 7.825039 LOC100506023  1.740666913 0.043453389 0.000663491 131.9005109 5.753024 5.487673 5.544653 11.096994 12.920903 12.58796 NSA2  1.91147922 0.043453389 0.000336849 129.8697361 3.024504 4.389936 4.285996 11.410858 11.142043 10.561895 DKFZP586I1420  1.811855658 0.043453389 0.00051378 129.7565838 1.874444 2.023048 2.165421 9.4931 9.042712 7.825039 ALS2CR11  1.876227772 0.043453389 0.000398095 129.5512648 1.874444 2.023048 2.165421 8.190235 10.019435 9.040427 SYTL2  1.815733438 0.043453389 0.00050017 126.4505035 2.201691 2.406905 2.995681 10.384422 8.564762 9.389334 NPM1  1.807635518 0.043453389 0.000534195 126.2179859 4.263463 5.297868 5.571599 13.009671 12.277642 11.085843 HNRPDL  1.641044066 0.043453389 0.000969718 123.9718851 5.335413 5.661685 5.723602 13.207998 12.615554 10.648433 NUDT4P1  1.644886848 0.043453389 0.000956108 123.4313424 1.874444 2.023048 3.90836 9.102956 9.075328 8.822008 GBP4  1.755743811 0.043453389 0.000643076 122.4065158 2.993831 4.389936 3.90836 9.929368 11.33847 10.176565 EIF4E  1.830671756 0.043453389 0.000479755 122.177064 5.779429 6.184248 6.072169 11.889562 13.117078 13.048081 CCDC53  1.901119239 0.043453389 0.000350459 119.3551415 2.201691 2.023048 2.165421 8.254907 9.064538 9.211256 REXO1L1  1.607322078 0.043453389 0.001078598 116.8998888 1.874444 2.023048 2.165421 6.954147 8.892178 9.220702 HSPA2  1.890116728 0.043453389 0.000370874 116.6670084 2.201691 2.023048 2.165421 8.222933 9.031674 9.276113 HSPA1B  1.447420164 0.043453389 0.001956448 115.393179 6.054828 7.476899 10.290431 12.905242 16.251649 15.72644 S100A4  1.923729909 0.043453389 0.000309629 114.2240591 2.993831 2.023048 2.165421 9.81605 9.540026 8.858771 HSP90AB2P  1.713727119 0.043453389 0.000711126 112.5574067 5.856559 3.872014 4.285996 10.686531 11.745539 11.813235 ODF2L  2.009494261 0.043453389 0.000241579 112.2550355 2.201691 2.023048 2.379345 9.012327 9.20872 8.79697 ALPK1  1.839164445 0.043453389 0.00045934 111.5506182 4.263463 3.872014 5.217616 10.955788 11.905258 11.065018 HTRA1  1.429785882 0.043453389 0.002153794 110.6174257 2.993831 2.809601 3.90836 7.36523 10.697795 10.166824 SCP2  1.459462552 0.043453389 0.001820347 110.3947184 1.874444 3.770995 2.165421 11.063531 8.951948 7.327219 RNF130  1.731917012 0.043453389 0.000683906 109.097839 2.993831 2.406905 4.285996 9.645614 9.76331 9.984774 RGS2  1.630971596 0.043453389 0.000983328 108.8304071 3.024504 2.406905 4.754917 11.332484 10.084974 9.172843 NANS  1.785611204 0.043453389 0.000581831 108.7541616 1.874444 2.809601 2.165421 10.564256 8.63937 8.66481 C2orf40  1.507074711 0.043453389 0.001541341 102.9875918 4.209882 6.466258 3.90836 10.896209 11.076418 10.871709 NUDT16P1  1.713972761 0.043453389 0.000704321 102.0659385 2.201691 2.406905 4.285996 8.875048 10.655275 10.42967 ID2  1.855985231 0.043453389 0.000425315 101.7708428 1.874444 2.023048 2.165421 9.565008 8.140553 8.692228 WBP5  1.701778978 0.043453389 0.000765567 101.1067993 2.993831 4.750708 3.935222 9.832037 10.666023 10.594958 SCGB2A2  1.295621129 0.043453389 0.003998639 100.5383317 1.874444 3.32135 2.165421 15.276814 8.817023 6.32627 FAM111B  1.641725993 0.043453389 0.000962913 99.44021447 3.839948 2.023048 2.165421 8.801178 9.944904 8.678584 TSPAN6  1.577243253 0.043453389 0.001214699 98.92829493 3.819732 2.023048 2.165421 10.448044 9.500541 7.849596 MTRNR2L5  1.875961939 0.043453389 0.0004049 96.13170883 1.874444 2.023048 2.165421 8.105092 8.609988 8.870819 FRA10AC1  1.815597976 0.043453389 0.000506975 95.7508315 3.024504 2.023048 2.165421 8.604261 9.031674 9.040427 TIMELESS  1.820527248 0.043453389 0.000493365 95.51583958 2.201691 2.809601 2.165421 8.779359 8.71031 10.18624 GBAS  1.708761447 0.043453389 0.000738346 95.16216427 2.201691 2.023048 2.165421 9.519665 8.737737 7.582913 NEIL1  1.794248436 0.043453389 0.00056822 94.92711748 1.874444 2.023048 2.165421 8.591796 8.055928 10.070856 COX17  1.807086789 0.043453389 0.000541 94.26613985 1.874444 2.406905 2.165421 9.154721 8.724089 8.03232 VPS29  1.879831614 0.043453389 0.00039129 93.27969155 1.874444 2.023048 2.165421 8.566539 9.075328 8.175185 BRD7P3  1.779594439 0.043453389 0.000588636 92.72338294 1.874444 2.406905 2.165421 8.700282 9.148683 7.920856 SPTSSA  1.881210649 0.043453389 0.000384485 92.2481629 6.008206 6.311907 6.450701 12.416848 13.163326 12.839356 SSBP2  1.653705956 0.043453389 0.000928887 92.09088911 2.201691 2.023048 2.379345 8.768324 8.904331 7.395512 RPL37  1.713115805 0.043453389 0.000717931 89.83259212 7.497182 8.595375 8.735088 15.940876 15.026399 13.986349 PRINS  1.703343767 0.043453389 0.000758761 89.39815136 3.024504 4.413323 3.764125 9.388882 10.50375 10.895496 LAMB1  1.300864559 0.043453389 0.003930589 89.33361805 5.658609 4.750708 5.225216 8.688623 12.418836 11.706348 ASTN2  1.778701368 0.043453389 0.000595441 88.9410239 5.263699 6.060401 5.544653 11.538127 12.603491 12.019431 SCGB1D2  1.289303444 0.043453389 0.004059884 88.89001699 1.874444 3.872014 2.165421 14.671711 8.63937 6.69026 SPARCL1  1.547325881 0.043453389 0.001309969 87.74998484 5.897292 4.911517 5.217616 10.088666 12.274133 12.352619 ABCC9  1.751429087 0.043453389 0.000649881 87.54727253 3.819732 4.830496 4.754917 10.271723 11.577343 11.173574 LINC00311  1.710463899 0.043453389 0.000724736 87.32826877 1.874444 3.32135 2.379345 9.111713 9.652384 8.32282 ZNF638  1.663370591 0.043453389 0.000867642 87.09798586 2.201691 2.023048 2.165421 8.757204 8.609988 7.36177 NNMT  1.546620081 0.043453389 0.001330384 86.64286536 4.639409 5.43468 3.764125 9.651632 11.076418 12.388682 CSDA  1.564885589 0.043453389 0.001241919 86.50388582 4.263463 2.406905 3.935222 10.967897 10.369915 8.650903 FLJ30679  1.809168563 0.043453389 0.000520585 86.26644468 1.874444 2.023048 2.165421 8.447068 10.232059 8.305171 KIFAP3  1.695183285 0.043453389 0.000785982 86.2019723 1.874444 2.023048 2.165421 7.394225 8.59507 8.503924 GOLGA8A  1.685234499 0.043453389 0.000813202 86.17042702 3.839948 3.360637 2.165421 10.263887 9.789758 8.882768 ZCRB1  1.630753387 0.043453389 0.000990133 85.25338234 1.874444 2.023048 2.379345 8.993498 8.436733 7.255535 LINC00550  1.599789195 0.043453389 0.001119428 85.00576375 4.639409 3.32135 2.379345 9.179923 10.970576 9.730839 FAM156A  1.859916134 0.043453389 0.00041851 83.57033195 1.874444 2.023048 2.165421 8.105092 8.829823 8.407967 LTV1  1.295780792 0.043453389 0.003991834 83.4826698 1.874444 2.406905 2.165421 8.79031 8.579995 5.634184 XCL2  1.406450137 0.043453389 0.00235182 83.27552994 1.874444 2.023048 2.165421 10.26781 8.402869 6.106561 PCNP  1.522140822 0.043453389 0.00147329 82.74568936 2.201691 2.023048 3.324375 8.895478 9.694987 7.352555 METTL3  1.697356632 0.043453389 0.000772372 82.43731548 3.350997 2.023048 2.995681 9.716222 8.94019 8.705744 TAF1A  1.76331782 0.043453389 0.000629466 80.7900104 5.982974 4.911517 4.944468 11.247622 11.978942 11.938737 BUD31  1.659059754 0.043453389 0.000901667 80.56677882 2.201691 3.360637 3.324375 9.252991 8.533804 9.928242 SNRPE  1.44655248 0.043453389 0.001963253 80.01631261 3.839948 2.023048 2.165421 10.162171 8.59507 7.492252 SMA4  1.854393939 0.043453389 0.00043212 79.2767086 1.874444 2.023048 2.165421 8.331873 8.486085 8.053616 SEPP1  1.594210951 0.043453389 0.001139843 78.3774597 4.263463 4.750708 5.217616 11.043074 12.04356 9.869404 DAP  1.426831249 0.043453389 0.002167404 77.25511038 4.815804 2.023048 2.379345 9.929368 8.63937 8.650903 LOC100507577  1.777731736 0.043453389 0.000602246 77.24192131 2.201691 2.023048 2.165421 8.711848 8.436733 7.849596 SRD5A3  1.538238892 0.043453389 0.00139163 77.24192131 3.839948 2.023048 2.165421 8.39062 8.436733 8.894619 RCN2  1.786163442 0.043453389 0.000575026 76.80562542 1.874444 2.023048 2.165421 8.286188 9.540026 8.053616 PENK  0.914976213 0.044110923 0.015605308 76.80562542 1.874444 2.023048 2.165421 8.286188 8.97518 2.921909 PGM5P2  1.635560543 0.043453389 0.000976523 76.58492221 1.874444 2.023048 2.165421 7.167419 8.36819 8.424409 MYEOV2  1.693775148 0.043453389 0.000792787 76.35312295 1.874444 2.023048 2.165421 9.633502 8.277663 7.611911 MARCH7  1.465747937 0.043453389 0.001765907 76.35312295 1.874444 2.023048 2.995681 9.552198 8.277663 6.931222 PLEKHG4B  1.691246176 0.043453389 0.000806397 76.34592584 1.874444 2.406905 2.165421 7.656039 8.4199 9.329475 CTSK  1.657867832 0.043453389 0.000908472 75.793297 2.993831 2.406905 2.165421 8.286188 10.840623 8.650903 B3GNT6  1.835465685 0.043453389 0.00047295 74.94925286 1.874444 2.023048 2.165421 8.051486 8.71031 8.25089 RAB6C  1.441137748 0.043453389 0.002024498 73.65572695 1.874444 2.809601 2.165421 9.012327 8.453372 6.649696 HAT1  1.825900902 0.043453389 0.00048656 73.51086639 1.874444 2.023048 2.165421 8.222933 8.737737 8.03232 MRPL51  1.739162714 0.043453389 0.000670296 73.38641922 1.874444 2.023048 2.165421 9.07636 8.220489 7.722406 LETMD1  1.662786021 0.043453389 0.000881252 73.38641922 1.874444 2.023048 2.165421 9.381659 8.220489 7.428484 AGR2  1.102299491 0.04349335 0.008119769 73.38641922 1.874444 2.023048 2.165421 10.686531 8.220489 4.146207 HMGB1  1.716566958 0.043453389 0.000697516 73.14253387 3.350997 3.770995 3.90836 9.963633 10.132246 9.230086 SH3YL1  1.385568479 0.043453389 0.002644437 72.76196462 2.201691 2.023048 2.165421 9.424465 8.350533 6.106561 SSBP1  1.48885082 0.043453389 0.001602586 72.70299186 2.201691 2.809601 2.165421 9.33006 8.385634 7.020304 N4BP2  1.769713911 0.043453389 0.000615856 72.39752441 1.874444 2.023048 2.165421 7.748771 8.200916 8.503924 ADD3  1.446031008 0.043453389 0.001983668 72.12258695 4.209882 2.406905 3.935222 8.993498 10.558612 8.579284 SLC25A34  1.54063354 0.043453389 0.001371215 71.22139426 5.753024 3.770995 4.944468 10.153715 11.224335 11.098707 GPR124  1.401742654 0.043453389 0.002433481 70.47473434 2.201691 2.406905 3.935222 7.074163 10.074256 9.454835 TCEAL4  1.673515508 0.043453389 0.000840422 70.40654115 2.993831 3.32135 4.285996 10.423634 10.356707 9.02972 BBS5  1.770316472 0.043453389 0.000609051 70.33945248 1.874444 2.023048 2.165421 8.139755 9.321782 8.010706 TMEM231  1.217252978 0.043453389 0.005264376 69.92017279 5.491121 2.406905 2.379345 8.527804 8.791075 8.534542 MLF1  1.578356542 0.043453389 0.001207894 69.77212321 2.993831 2.023048 2.379345 7.607339 9.540026 8.503924 NUBPL  1.458889222 0.043453389 0.001833957 69.20197918 1.874444 2.023048 3.90836 8.069577 8.751258 8.135789 SNHG4  1.432548484 0.043453389 0.002112964 69.17804025 1.874444 2.023048 2.165421 6.283686 8.277663 8.213534 CXCL14  0.96220209 0.043778104 0.013275944 69.07376332 4.309025 6.092406 5.592916 6.651882 12.418836 11.702982 SDHD  1.334042198 0.043453389 0.003318135 68.91673571 1.874444 2.809601 2.165421 8.361545 8.916384 6.106561 SEC61G  1.709367061 0.043453389 0.000731541 68.14216959 2.993831 2.023048 2.379345 8.604261 8.469821 8.374509 PON2  1.691338951 0.043453389 0.000799592 68.14216959 1.874444 2.406905 2.379345 10.119387 8.469821 7.920856 HBP1  1.679649016 0.043453389 0.000820007 67.76725294 3.839948 3.32135 4.285996 10.298817 9.409671 9.922465 BHMT2  1.398157011 0.043453389 0.002460701 67.38609368 2.993831 2.023048 2.165421 6.651882 8.2398 9.211256 PPIA  1.661242799 0.043453389 0.000894862 67.13840789 6.554045 6.762934 6.326717 11.869047 12.859021 12.623111 ACTG2  1.247105706 0.043453389 0.004706363 66.49012465 1.874444 2.406905 2.165421 8.895478 8.220489 5.426231 PPWD1  1.542531026 0.043453389 0.0013508 66.46423302 1.874444 2.023048 2.379345 8.65307 8.077554 6.931222 TATDN1  1.435006348 0.043453389 0.002092548 66.46423302 1.874444 2.023048 2.165421 9.344992 8.077554 6.32627 COX4I1  1.663688649 0.043453389 0.000860837 66.05695683 5.316227 4.80797 5.723602 12.255316 11.30448 10.853609 MUCL1  1.361022676 0.043453389 0.002957469 66.01609304 4.209882 5.148082 2.995681 13.474327 9.375155 9.040427 CCDC148  1.666417704 0.043453389 0.000854032 65.85659481 1.874444 2.406905 2.165421 8.206677 8.518072 7.523109 LOC100507584  1.378889104 0.043453389 0.002746512 64.6344836 2.993831 2.023048 2.165421 6.498222 8.402869 9.008063 CLU  1.480628323 0.043453389 0.001670636 64.44572806 4.309025 6.044198 4.724406 12.054211 11.175024 9.857343 TOP2B  1.620680744 0.043453389 0.001017353 64.0191368 3.350997 3.32135 2.995681 9.513069 9.321782 8.357484 AGR3  1.190971261 0.043453389 0.005957809 63.80223603 3.024504 2.023048 2.165421 9.973276 8.160956 5.446557 C8orf59  1.579039887 0.043453389 0.001194284 63.61700766 3.839948 3.32135 2.165421 9.577706 9.312691 8.519314 SYNPO2  1.348636836 0.043453389 0.003107179 63.52197144 6.099991 3.770995 3.935222 9.924405 9.841243 10.166824 ANKRA2  1.299220119 0.043453389 0.003944199 63.49764466 1.874444 2.023048 2.165421 8.346785 8.011679 5.634184 METTL9  1.482599976 0.043453389 0.001663831 63.4548232 4.263463 2.023048 2.165421 9.179923 9.348715 8.010706 TRIM58  1.655609465 0.043453389 0.000922082 63.44208563 1.874444 2.809601 2.165421 7.70315 8.518072 8.79697 PLK2  1.430182539 0.043453389 0.002146989 63.39053395 2.993831 3.360637 5.018694 9.137671 9.44338 9.346832 CHMP2B  1.448769749 0.043453389 0.001922423 62.90718247 1.874444 2.809601 4.285996 10.240121 9.198885 7.849596 CD48  1.672049138 0.043453389 0.000847227 61.81627289 3.024504 2.023048 2.995681 8.974419 8.332658 8.858771 C14orf2  1.601642733 0.043453389 0.001112623 61.76640587 4.682076 4.351315 2.379345 10.145209 9.796295 10.630827 TMEM50A  1.1769806 0.043453389 0.00625723 61.69181251 4.639409 2.023048 2.165421 10.586416 9.064538 6.106561 API5  1.247261419 0.043453389 0.004699558 60.75654758 1.874444 2.406905 4.754917 8.331873 8.36819 7.800057 CD2  1.618406033 0.043453389 0.001037768 60.58129954 1.874444 2.023048 2.165421 8.915622 7.25505 7.943848 UG0898H09  1.441054827 0.043453389 0.002031303 60.49735265 4.743564 2.023048 3.935222 8.745998 9.492512 10.662364 GPLD1  1.379815947 0.043453389 0.002726097 60.48688242 1.874444 3.872014 3.90836 7.792994 9.075328 9.973643 PPT1  1.523784225 0.043453389 0.001452875 60.21843259 3.350997 2.023048 2.165421 8.206677 8.077554 7.96648 LUM  1.4691771 0.043453389 0.001738687 60.21559926 4.815804 4.389936 5.974145 10.402378 12.532831 10.302002 TOP1P1  1.516181741 0.043453389 0.00151412 59.3643455 2.993831 3.32135 3.90836 9.799885 9.615895 8.155622 PITRM1  1.589520795 0.043453389 0.001173869 59.32962928 2.201691 2.809601 2.165421 8.700282 8.36819 7.492252 GNG11  1.157979692 0.043453389 0.006665532 59.27383745 5.700376 2.406905 2.165421 8.239009 8.296229 9.008063 NUDT9  1.591693272 0.043453389 0.001167064 59.14136941 4.743564 4.413323 3.90836 9.794456 10.765988 9.832914 DLC1  1.436271223 0.043453389 0.002072133 58.9993446 1.874444 2.809601 4.285996 8.239009 9.20872 8.692228 GNPTG  1.251006579 0.043453389 0.004617897 58.88495099 3.024504 2.809601 2.379345 8.875048 8.904331 6.106561 OR11A1  1.430393383 0.043453389 0.002140184 58.66564075 1.874444 2.023048 2.165421 6.339437 8.077554 7.897492 GTF3A  1.519092461 0.043453389 0.0014869 58.55343516 1.874444 2.023048 2.165421 9.733347 7.89473 6.924055 MSH3  1.461677519 0.043453389 0.001806737 58.09168605 3.350997 2.406905 2.165421 7.210813 8.751258 9.211256 THUMPD1  1.417095149 0.043453389 0.002215039 57.86115524 3.819732 2.023048 2.165421 7.877571 8.258856 8.095288 AREG  0.832883218 0.044797567 0.019843484 57.77096022 1.874444 3.770995 3.935222 12.218289 9.623267 2.921909 BCO2  1.652383994 0.043453389 0.000935692 57.70781913 1.874444 2.023048 2.165421 7.42265 8.751258 7.873743 DDHD1  1.556078511 0.043453389 0.001289554 57.63323771 4.309025 2.406905 3.935222 9.212855 10.157854 9.389334 LOC401074  1.611799847 0.043453389 0.001058183 57.59860672 1.874444 2.406905 2.165421 7.814607 9.652384 7.722406 STXBP3  1.541650609 0.043453389 0.00136441 57.56461128 1.874444 2.023048 2.165421 9.030914 7.870158 6.931222 EFCAB4A  1.426180066 0.043453389 0.002174209 56.97599942 2.201691 2.023048 2.995681 9.4931 8.033973 6.931222 TMEM17  1.732072961 0.043453389 0.000677101 56.90132997 2.201691 2.023048 2.165421 7.995811 7.819723 8.579284 ITPR1  1.661592255 0.043453389 0.000888057 56.57579413 1.874444 2.023048 2.165421 8.033165 7.845161 7.36177 RPL23P8  1.418889418 0.043453389 0.002208234 56.57094654 8.224469 8.407985 8.710484 14.854834 14.229975 12.740216 USMG5  1.279768138 0.043453389 0.00418918 56.30308342 4.682076 5.297868 2.379345 11.349244 10.11666 8.194487 DYNC2LI1 1.492102969 0.043453389 0.001561756 56.13765012 1.874444 2.023048 3.324375 7.937902 7.68534 8.232333 TUBA1A 1.589065557 0.043453389 0.001180674 56.06002393 4.963444 5.809601 4.944468 11.18883 11.618502 10.437793 TRIP13 1.478101842 0.043453389 0.001684246 55.6753434 1.874444 2.406905 3.324375 7.679787 7.870158 9.123341 QARS 1.493715001 0.043453389 0.001554951 55.28257456 3.819732 3.872014 3.324375 10.544987 9.608485 8.32282 NDUFAB1 1.603960178 0.043453389 0.001099013 54.55432044 1.874444 2.809601 2.165421 8.579223 8.033973 7.640338 ACTA2 1.084132897 0.043516135 0.008805036 54.41355806 1.874444 6.060401 2.165421 9.615142 8.140553 7.640338 IGFBP7 1.533128851 0.043453389 0.00141885 54.35845954 7.392123 5.195784 6.704285 13.156556 12.408206 11.964266 IKBKAP 1.629863814 0.043453389 0.000996938 54.23709835 2.201691 2.023048 2.379345 7.42265 8.140553 8.03232 ASB4 1.245046811 0.043453389 0.004753998 53.94510074 3.024504 2.023048 5.018694 7.995811 8.777924 8.784285 FAM192A 1.62042571 0.043453389 0.001024158 53.87659078 2.201691 2.023048 2.995681 8.591796 8.453372 7.774634 TMEM9 1.475841785 0.043453389 0.001697856 53.52562077 2.201691 3.32135 3.324375 9.23707 8.332658 7.943848 SNHG5 1.614652598 0.043453389 0.001051378 53.3518941 1.874444 2.406905 2.379345 9.196483 7.96603 7.611911 PCF11 1.388454947 0.043453389 0.002589997 53.3518941 1.874444 2.023048 3.90836 8.122528 8.4199 7.611911 TRIM59 1.457570981 0.043453389 0.001847567 53.18306912 1.874444 2.023048 3.764125 7.607339 8.777924 8.456743 PSIP1 1.486005217 0.043453389 0.001629806 53.17005402 1.874444 3.32135 2.165421 7.897963 8.055928 7.800057 LMOD1 1.593751306 0.043453389 0.001146649 53.15269239 2.201691 3.360637 2.165421 9.040118 8.71031 7.897492 LGALS3 1.655847023 0.043453389 0.000915277 53.07275475 4.963444 4.911517 5.723602 11.400174 11.419041 10.641416 FASTKD2 1.663093547 0.043453389 0.000874447 53.05103103 1.874444 2.406905 2.165421 8.051486 7.89473 7.611911 NUP133 1.592058655 0.043453389 0.001160259 53.05103103 2.201691 2.023048 2.165421 7.177844 7.89473 8.095288 KLHL7-AS1 1.605178652 0.043453389 0.001092208 52.91933604 3.024504 2.023048 2.165421 7.748771 8.71031 8.32282 BRP44L 1.574914581 0.043453389 0.001228309 52.62060003 1.874444 2.023048 2.379345 8.316805 7.740604 7.180104 FAM200A 1.490969843 0.043453389 0.001582171 52.62060003 1.874444 2.023048 2.165421 6.664985 7.740604 8.440667 C16orf80 1.486472 0.043453389 0.001623001 52.62060003 1.874444 2.023048 2.165421 9.229044 7.740604 6.73963 BPHL 1.133394708 0.043453389 0.007257571 52.62060003 1.874444 2.023048 2.165421 4.739845 7.740604 8.407967 CD69 1.314106946 0.043453389 0.003644777 51.8182328 3.024504 2.023048 4.508334 10.203722 7.107836 9.710869 FBXW4 1.311814589 0.043453389 0.003699217 51.57598181 2.993831 3.360637 2.165421 9.049264 8.696398 6.69026 LOC100859930 1.556766111 0.043453389 0.001282749 51.53009294 3.024504 3.32135 2.165421 8.711848 8.055928 8.758577 FGFR1OP2 1.455211655 0.043453389 0.001854372 51.50604618 1.874444 2.023048 2.995681 7.856887 8.682351 7.033813 LOC283104 1.5573986 0.043453389 0.001275944 51.41707166 2.201691 3.32135 2.165421 8.376156 8.609988 7.849596 FOXM1 1.450908287 0.043453389 0.001881592 51.41707166 3.350997 3.360637 2.165421 8.331873 9.555522 7.849596 DDOST 1.395716358 0.043453389 0.002481116 51.11806947 4.639409 3.32135 2.165421 8.488001 9.321782 8.997112 HSPA6 1.206110167 0.043453389 0.005475332 50.82479756 1.874444 3.770995 6.282905 9.438455 10.666023 8.60836 TRAPPC2L 1.559059581 0.043453389 0.001262334 50.64305361 1.874444 2.023048 2.165421 8.501391 7.68534 7.020304 SRGN 1.303216971 0.043453389 0.003855733 50.61192066 6.58615 2.023048 5.225216 11.092577 9.944904 10.886622 GRAMD3 1.31245776 0.043453389 0.003685607 50.34684703 2.993831 3.32135 2.995681 8.65307 8.97518 6.931222 CMKLR1 1.439974974 0.043453389 0.002038108 50.21710565 4.639409 3.360637 4.754917 10.329172 8.867558 10.405024 OR1J1 1.462635218 0.043453389 0.001793127 49.69678306 3.819732 2.809601 4.449894 8.566539 10.084974 9.446808 SDHB 1.279968458 0.043453389 0.004182375 49.65429477 1.874444 2.023048 2.165421 9.794456 7.656894 5.634184 MTRNR2L8 1.14853349 0.043453389 0.006896904 49.64604431 8.984007 11.971005 12.360493 17.9941 15.136436 16.001611 FMO1 1.017504819 0.043581008 0.011150732 49.57929852 1.874444 2.023048 3.90836 4.894482 9.540026 7.825039 ARPC2 1.359692536 0.043453389 0.002977884 49.25842145 5.263699 3.872014 3.324375 9.040118 9.540026 9.494312 C13orf15 1.559100619 0.043453389 0.001255529 49.23190156 3.839948 3.770995 3.324375 11.017672 9.392516 8.809543 CRIM1 1.404335344 0.043453389 0.002385846 49.04918518 2.993831 4.351315 2.379345 9.621288 8.609988 8.155622 TRAPPC12 1.542077607 0.043453389 0.001357605 48.82980598 3.024504 2.023048 2.379345 8.316805 7.989035 7.668215 RERG 1.353580167 0.043453389 0.003045934 48.68655809 3.839948 2.023048 2.995681 9.4454 7.713236 7.897492 NDUFA12 1.349872936 0.043453389 0.003086764 48.66554626 1.874444 2.023048 2.165421 10.170577 7.627877 6.129407 CCDC142 1.247830974 0.043453389 0.004679143 48.54459561 2.993831 2.023048 4.754917 7.748771 8.59507 8.719135 AHSA2 1.523550347 0.043453389 0.001466485 48.53492918 3.350997 2.023048 3.935222 9.102956 8.951948 8.66481 NUP54 1.64565965 0.043453389 0.000949302 48.46566641 1.874444 2.023048 2.165421 7.531061 7.473335 8.155622 PPCS 1.093083876 0.04349335 0.008487241 48.23933414 2.201691 2.406905 2.165421 8.553743 7.793829 4.790662 RIOK1 1.554499834 0.043453389 0.001303164 48.07234315 1.874444 2.406905 2.379345 8.433162 7.191402 7.96648 MYH11 1.400384219 0.043453389 0.002447091 48.04000683 2.993831 4.389936 2.165421 8.801178 8.579995 8.488368 C14orf166 1.110429163 0.043485739 0.007901327 47.98515005 3.839948 2.023048 2.165421 9.424465 8.314558 5.446557 SDPR 1.528826607 0.043453389 0.001425655 47.94638146 2.201691 2.023048 2.165421 7.748771 7.094585 9.153246 LINC00116 1.435184958 0.043453389 0.002085743 47.94638146 3.024504 3.32135 2.165421 7.748771 7.91889 9.018932 ANKRD30A 0.964015512 0.043778104 0.013194284 47.6768087 1.874444 2.023048 2.165421 8.286188 7.598264 3.676349 TRIM4 1.517903873 0.043453389 0.00150051 47.43763648 1.874444 3.872014 3.90836 9.322536 9.47632 8.771488 TAF7 1.45084417 0.043453389 0.001888397 47.41216254 4.682076 3.770995 2.165421 8.822673 10.095614 9.33818 TSPAN13 1.19113304 0.043453389 0.005944199 47.36570059 2.201691 2.809601 2.165421 9.220972 7.767462 5.580533 NCRUPAR 1.184335036 0.043453389 0.006073494 47.33736239 2.201691 2.809601 2.165421 5.579836 7.819723 8.374509 TXN 1.37895339 0.043453389 0.002739707 47.32022999 4.743564 4.389936 4.724406 11.393008 10.288791 8.745549 TTC23 1.575782543 0.043453389 0.001221504 47.17221773 1.874444 2.023048 2.165421 7.074163 8.011679 7.582913 LOC494558 1.346818519 0.043453389 0.003134399 47.12945204 4.743564 3.360637 2.379345 7.937902 9.339793 9.875397 UQCRQ 1.38307657 0.043453389 0.002692072 47.10625677 5.856559 4.351315 3.764125 10.701112 9.909162 9.656224 TRA2B 1.515886798 0.043453389 0.001520925 46.91340918 5.744513 4.736586 5.018694 10.570622 10.320883 10.791579 OLFML3 1.331512079 0.043453389 0.003358966 46.79253506 1.874444 2.406905 4.449894 7.42265 9.834907 8.564524 PSMD10 1.251820898 0.043453389 0.004597482 46.77985834 2.201691 2.023048 2.165421 8.540832 7.713236 5.580533 C7orf55 1.467418008 0.043453389 0.001759102 46.68808276 1.874444 2.023048 2.165421 8.014609 7.56803 6.587378 CTSC 1.342591047 0.043453389 0.00320245 46.47540701 7.427999 5.661685 4.285996 10.998912 12.082858 11.200081 WDR91 1.387972805 0.043453389 0.002617217 46.4578361 3.819732 4.389936 2.165421 8.222933 9.357582 9.478651 OSGEP 1.465263983 0.043453389 0.001772712 46.2144858 2.201691 2.023048 3.324375 8.239009 7.942653 7.553321 UROD 1.222650641 0.043453389 0.00514869 46.05448993 5.263699 3.32135 2.379345 8.286188 8.867558 8.84662 CPPED1 1.193727842 0.043453389 0.005842123 46.0350933 3.024504 3.360637 5.596986 8.885299 8.916384 8.650903 EFHA1 1.461384558 0.043453389 0.001813542 45.92057625 1.874444 3.360637 2.165421 8.801178 8.033973 7.395512 GSTK1 1.511118558 0.043453389 0.001527731 45.54988718 3.024504 4.830496 5.217616 10.726991 10.106175 10.086439 CDKN1B 1.412085189 0.043453389 0.002276965 45.54748689 3.024504 2.809601 3.324375 10.580119 8.533804 7.553321 WDR61 1.362437942 0.043453389 0.002930248 45.54023245 4.263463 3.360637 3.324375 9.772533 8.928336 7.943848 DDX26B 1.48532569 0.043453389 0.001636611 45.50688735 1.874444 2.023048 2.165421 7.531061 8.140553 6.69026 CPE 1.339294032 0.043453389 0.00325689 45.44430871 5.658609 4.351315 6.031658 10.444582 11.821211 9.857343 ARMCX2 1.516230905 0.043453389 0.001507315 45.41059124 1.874444 2.809601 2.165421 7.33564 8.314558 7.695565 C1orf43 1.324423029 0.043453389 0.003508676 45.41059124 4.263463 2.809601 2.165421 8.641022 8.314558 7.774634 LOC100286844 1.607849608 0.043453389 0.001071793 45.06308174 2.201691 2.023048 2.379345 7.42265 7.96603 7.695565 ESD 1.47935305 0.043453389 0.001677441 45.02909103 2.993831 2.023048 3.764125 8.361545 9.25691 8.175185 FAM13A-AS1 1.34622041 0.043453389 0.00314801 44.96673738 1.874444 2.023048 3.935222 7.36523 8.564762 7.96648 C6orf125 1.609002638 0.043453389 0.001064988 44.8590162 1.874444 2.023048 2.165421 8.301578 7.473335 7.36177 LCMT1 1.347650621 0.043453389 0.003120789 44.71066871 1.874444 2.023048 2.165421 7.656039 7.505595 6.051818 MFF 1.413350928 0.043453389 0.002249064 44.55954665 3.024504 2.023048 3.324375 8.955085 8.502167 7.291822 CCNG1 1.2914608 0.043453389 0.004032664 44.47482313 2.201691 4.750708 2.165421 9.755869 8.332658 7.640338 DKK3 1.403636687 0.043453389 0.002392651 44.29851721 2.201691 3.360637 2.379345 8.801178 8.829823 6.942983 SMARCD3 1.321852303 0.043453389 0.003556312 44.21529072 3.839948 2.023048 2.165421 7.631894 7.56803 8.010706 LOC100507377 1.44605423 0.043453389 0.001976863 43.72198226 1.874444 2.023048 2.165421 6.544171 7.473335 8.374509 DCTN6 1.032970004 0.043577906 0.01047363 43.72198226 1.874444 2.023048 2.165421 8.604261 7.473335 4.146207 IMMT 1.465211561 0.043453389 0.001779517 43.6907014 3.839948 2.809601 3.324375 8.514658 8.258856 9.414247 DZIP3 1.487817212 0.043453389 0.001616196 43.34135597 2.201691 2.023048 2.995681 7.918071 7.713236 7.46072 MSMO1 1.022115956 0.043577906 0.010954066 43.30365941 5.316227 4.736586 2.379345 11.702223 10.173004 6.195186 RAB13 1.217060254 0.043453389 0.005277986 43.07348259 5.491121 3.32135 2.995681 9.396069 8.817023 8.424409 HCG18 1.528499119 0.043453389 0.001439265 42.93417375 5.316227 4.750708 5.225216 10.174762 11.041076 10.341502 FAM166A 1.436612261 0.043453389 0.002058523 42.75676716 1.874444 2.023048 3.324375 8.206677 7.292524 7.943848 TSTD1 1.238113063 0.043453389 0.004842463 42.75676716 1.874444 4.80797 2.165421 9.171571 7.292524 8.391335 GPR132 1.584706913 0.043453389 0.001187479 42.73933339 1.874444 2.406905 2.165421 7.394225 7.627877 7.582913 PAPSS1 1.469113279 0.043453389 0.001745492 42.73933339 3.350997 2.809601 2.165421 8.361545 8.751258 7.582913 C12orf36 1.431417987 0.043453389 0.002133379 42.73933339 1.874444 3.32135 2.165421 7.477873 8.71031 7.582913 RBM34 1.4166217 0.043453389 0.002221844 42.73331073 1.874444 2.023048 2.165421 7.771052 7.440337 6.385515 GTF3C6 1.411474328 0.043453389 0.00228377 42.73331073 1.874444 2.023048 2.165421 8.40494 7.440337 6.385515 UBE2Q2 1.385312403 0.043453389 0.002651242 42.73331073 1.874444 2.023048 2.165421 9.16317 7.440337 6.32627 C8orf40 1.363947141 0.043453389 0.002903028 42.73331073 1.874444 2.023048 2.165421 7.995811 7.440337 6.129407 SURF1 1.313444203 0.043453389 0.003665192 42.73331073 1.874444 2.023048 2.165421 8.604261 7.440337 5.874974 TMEM218 1.428905497 0.043453389 0.002160599 42.65029818 3.024504 2.023048 2.379345 7.109557 7.793829 8.622681 HNRNPR 1.366854964 0.043453389 0.002869003 42.44290195 3.839948 3.360637 3.90836 10.698207 9.2474 7.849596 SUMO1P3 1.384841881 0.043453389 0.002664852 42.43513285 3.024504 2.023048 2.995681 8.964784 8.402869 6.942983 ERGIC2 1.405748318 0.043453389 0.002372235 42.38367042 1.874444 2.023048 2.165421 6.339437 7.713236 7.428484 LHX6 1.200882398 0.043453389 0.005631848 42.38367042 1.874444 2.023048 2.165421 7.631894 5.317867 7.428484 ACAT1 1.340431433 0.043453389 0.00324328 42.2526482 3.819732 2.023048 2.995681 7.450526 8.098861 9.220702 RBM41 1.594819382 0.043453389 0.001133038 42.15946375 2.993831 3.32135 2.995681 8.254907 8.65384 8.719135 PPIH 1.595217589 0.043453389 0.001126233 41.96278636 1.874444 2.023048 2.165421 7.814607 7.414086 7.218312 TRAPPC2 1.546635447 0.043453389 0.001323579 41.96278636 1.874444 2.023048 2.185421 8.033165 7.417086 7.020304 MTRNR2L2 1.385174447 0.043453389 0.002658047 41.96278636 1.874444 2.023048 2.165421 11.205289 7.414086 6.69026 PA2G4 1.267816237 0.043453389 0.004318476 41.96278636 1.874444 2.023048 2.165421 8.885299 7.414086 5.634184 NMNAT1 1.328071996 0.043453389 0.003427016 41.87788429 2.993831 2.023048 2.379345 6.544171 7.767462 9.103055 RAB32 1.561236212 0.043453389 0.001248724 41.87160178 1.874444 2.406905 2.165421 7.957464 7.25505 7.553321 WHAMMP3 1.374727452 0.043453389 0.002780538 41.87160178 2.993831 2.023048 2.165421 6.814118 8.502167 7.553321 ZNF518A 1.413564365 0.043453389 0.002242259 41.74465515 1.874444 2.023048 2.165421 8.051486 7.406567 6.385515 THADA 1.306835109 0.043453389 0.003774073 41.74465515 1.874444 2.023048 2.165421 7.556937 7.406567 5.882028 GOLGA8B 1.163736681 0.043453389 0.006529432 41.74465515 1.874444 2.023048 2.165421 7.70315 7.406567 5.106393 DFNA5 1.005193684 0.043588662 0.011640014 41.74465515 1.874444 2.023048 2.165421 7.679787 7.406567 4.146207 ZNF277 1.20070631 0.043453389 0.005652263 41.67824488 2.201691 4.750708 2.995681 8.433162 8.469821 7.582913 CYC1 1.391859779 0.043453389 0.002528751 41.6744441 1.874444 3.360637 2.995681 9.914429 8.277663 7.255535 CIR1 1.523715219 0.043453389 0.00145968 41.44401553 3.350997 3.32135 3.764125 9.171571 8.724089 8.456743 PSMA5 1.314131429 0.043453389 0.003637972 41.42599842 4.263463 2.023048 2.165421 9.171571 8.119857 7.395512 RAD50 1.308659323 0.043453389 0.003746853 41.42599842 3.839948 2.023048 2.379345 7.995811 7.819723 7.395512 NDUFA5 1.381709522 0.043453389 0.002705682 41.40489187 2.201691 2.023048 2.165421 7.856887 7.53715 6.32627 ID4 1.338933687 0.043453389 0.003263695 41.40489187 2.993831 2.023048 2.165421 8.628872 7.53715 6.618407 ANO7 1.555812959 0.043453389 0.001296359 41.36099126 5.056948 5.297868 5.544653 10.427146 10.98209 10.576683 POTEM 1.257244921 0.043453389 0.004515822 41.33842066 1.874444 2.406905 2.379345 5.743334 8.682351 7.748756 TMEM14C 1.442674436 0.043453389 0.001997278 41.29025674 3.839948 2.406905 2.995681 9.120418 8.855089 7.774634 LPHN2 1.546166302 0.043453389 0.00133719 41.23049802 2.201691 2.809601 2.165421 7.531061 7.942653 7.800057 TARBP1 1.368079503 0.043453389 0.002855393 41.1461104 2.201691 3.360637 2.165421 8.723321 7.819723 7.020304 FKBP3 1.360010375 0.043453389 0.002971079 41.00387972 3.350997 3.872014 2.165421 9.506443 8.65384 7.523109 RPS8 1.313242754 0.043453389 0.003671997 40.86067925 7.355332 8.170275 8.525393 15.13044 13.522916 11.967075 EFEMP1 1.345181954 0.043453389 0.003168425 40.79152379 3.839948 4.413323 4.508334 8.286188 10.554762 9.76352 EIF3E 1.450038836 0.043453389 0.001908813 40.70453366 4.815804 4.911517 3.935222 11.480129 10.162922 9.220702 ISCU 1.431579404 0.043453389 0.002126574 40.56713041 4.963444 3.770995 4.508334 10.115039 9.853832 9.113234 CCPG1 1.528731479 0.043453389 0.00143246 40.56551863 1.874444 2.023048 2.165421 7.36523 8.402869 7.033813 THSD7A 1.488964105 0.043453389 0.001595781 40.56551863 1.874444 2.023048 2.379345 7.36523 8.160956 6.924055 SP110 1.447744901 0.043453389 0.001942838 40.4683409 1.874444 2.023048 2.165421 6.550689 7.68534 7.36177 WBP4 1.413152326 0.043453389 0.002255869 40.4683409 1.874444 2.023048 2.165421 6.395481 7.56803 7.36177 RPL7 1.355704319 0.043453389 0.003025519 40.28674451 7.730559 8.07747 8.13956 14.422425 13.409703 12.068646 POF1B 1.523838928 0.043453389 0.00144607 40.21069629 1.874444 2.023048 2.165421 6.954147 8.098861 7.352555 CDO1 1.36920719 0.043453389 0.002841783 40.21069629 1.874444 2.023048 2.165421 6.183122 7.819723 7.352555 PDGFD 1.160482073 0.043453389 0.006611092 40.21069629 1.874444 2.023048 2.165421 5.026959 8.453372 7.352555 PSMA3 1.335577999 0.043453389 0.003290915 40.20952181 4.263463 2.023048 3.324375 9.466036 8.65384 7.722406 BDH2 1.403601523 0.043453389 0.002399456 40.11694283 4.682076 2.406905 3.90836 8.745998 10.008216 9.072081 STARD10 1.250422197 0.043453389 0.004631507 39.97769849 2.201691 2.023048 2.995681 8.316805 7.53715 6.129407 OBFC2B 1.453744377 0.043453389 0.001861177 39.89178909 4.209882 3.32135 3.324375 8.801178 8.63937 8.809543 PLBD1 1.462346937 0.043453389 0.001799932 39.74198427 1.874444 2.023048 2.165421 7.33564 8.533804 6.722123 C7orf50 1.32994999 0.043453389 0.003406601 39.73813364 3.819732 2.023048 2.165421 7.477873 7.473335 9.061607 CRNDE 1.447735123 0.043453389 0.001949643 39.70751324 2.993831 3.770995 3.764125 10.052735 8.737737 8.305171 DIMT1 1.309418202 0.043453389 0.003740048 39.56068284 1.874444 3.360637 2.379345 8.993498 7.68534 6.722123 GOLGA4 1.237573436 0.043453389 0.004856073 39.51069887 2.993831 2.023048 4.449894 8.94532 8.332658 7.327219 WHAMMP2 1.223517522 0.043453389 0.005114665 39.51069887 1.874444 2.023048 2.165421 5.448591 7.767462 7.327219 LOC100287015 1.209760998 0.043453389 0.005441307 39.48959045 1.874444 2.809601 4.508334 7.177844 8.63937 8.32282 CCDC125 1.346385086 0.043453389 0.003141204 39.47920976 2.201691 3.872014 2.995681 7.504712 8.579995 8.391335 CD6 1.400324753 0.043453389 0.002453896 39.40219283 1.874444 2.023048 3.764125 8.843852 7.174648 8.549611 INPP4B 1.341667752 0.043453389 0.00321606 39.26846672 1.874444 2.406905 2.165421 8.122528 6.205902 7.46072 PLN 1.447955565 0.043453389 0.001936033 39.25656159 1.874444 2.023048 2.165421 6.664985 7.31791 8.593895 TAZ 1.364268243 0.043453389 0.002889418 39.25656159 1.874444 2.023048 2.165421 6.183122 7.31791 7.492252 CA2 1.100125961 0.04349335 0.008221844 39.25656159 1.874444 2.023048 2.165421 11.13615 7.31791 4.562324 HERC4 1.302668709 0.043453389 0.003869343 39.18845706 2.993831 2.023048 2.165421 8.286188 7.767462 6.32627 SRP9 1.315831463 0.043453389 0.003617557 39.12890373 6.008206 4.351315 4.724406 11.298369 10.865703 9.040427 PRMT10 1.406410991 0.043453389 0.002358625 38.99196047 1.874444 2.023048 2.165421 7.450526 6.373501 7.36177 TTC37 1.468192955 0.043453389 0.001752297 38.79705492 3.350997 3.32135 2.379345 8.628872 8.518072 7.873743 SNORD36A 1.381553079 0.043453389 0.002712487 38.79399871 1.874444 2.023048 3.324375 7.877571 7.68534 7.152205 ESR1 1.413593415 0.043453389 0.002235454 38.68038585 3.024504 2.023048 2.995681 8.566539 7.174648 8.269212 PPIP5K2 1.436480191 0.043453389 0.002065328 38.63199311 3.024504 2.023048 2.379345 8.139755 8.296229 7.033813 LAPTM5 1.305262789 0.043453389 0.003794488 38.57185413 2.993831 2.023048 4.285996 8.925589 7.292524 9.192178 ARL5B 1.128916867 0.043453389 0.007359646 38.57185413 1.874444 2.023048 4.724406 8.316805 7.292524 7.291822 SETD7 1.125651442 0.043453389 0.007448112 38.55307345 4.963444 2.023048 2.165421 7.937902 8.181074 7.291822 TIMM23 1.398014149 0.043453389 0.002467506 38.40077714 2.201691 3.32135 2.165421 8.41912 7.473335 7.428484 SERPINA3 1.090161231 0.043516135 0.008600885 38.30238585 4.963444 8.158996 5.596986 13.673048 10.856349 9.737435 RAB9A 1.384299959 0.043453389 0.002678462 38.29254369 3.350997 2.406905 2.165421 8.447068 8.609988 6.942983 SEPT2 1.187339094 0.043453389 0.006012249 38.28389813 6.765086 4.736586 4.508334 9.767 10.284148 10.070856 UBE2NL 1.261437949 0.043453389 0.004447771 38.25366027 1.874444 3.32135 3.764125 9.02165 7.292524 7.774634 APOF 1.304627375 0.043453389 0.003835318 38.09494312 1.874444 2.023048 2.165421 7.274575 7.942653 5.882028 NAA40 1.433897504 0.043453389 0.002099354 38.04861649 6.45321 6.092406 5.702912 10.62363 11.52517 11.702982 CMC1 1.11846103 0.043485739 0.007629126 37.96245679 1.874444 2.023048 2.165421 8.553743 7.269549 4.790662 SNX17 1.453689637 0.043453389 0.001867982 37.95786248 3.839948 2.809601 2.995681 8.501391 8.055928 8.96375 GPRASP1 1.299712561 0.043453389 0.003937394 37.8998065 1.874444 2.023048 2.995681 6.244586 8.2398 7.695565 MRPS31 1.257910811 0.043453389 0.004509017 37.8127138 3.350997 2.023048 2.165421 8.591796 7.767462 6.32627 LOC375190 1.448955474 0.043453389 0.001915618 37.70965681 1.874444 2.023048 2.165421 7.25991 7.656894 6.587378 SPATA6 1.241297889 0.043453389 0.004794828 37.70965681 1.874444 2.023048 2.165421 7.25991 7.56803 5.580533 TXNIP 1.188615764 0.043453389 0.005991834 37.65317973 6.707871 4.750708 6.564874 10.398804 11.94257 10.18624 MRPL15 1.334379529 0.043453389 0.00331133 37.58283222 1.874444 2.023048 2.165421 7.531061 7.25505 6.051818 RAB25 1.115733348 0.043485739 0.007724396 37.58283222 1.874444 2.023048 2.165421 8.40494 7.25505 4.790662 P2RY6 1.374554258 0.043453389 0.002787343 37.5567624 4.309025 2.406905 4.285996 8.361545 9.540026 9.446808 MATN2 1.390500842 0.043453389 0.002549166 37.4785643 1.874444 3.360637 2.379345 7.607339 8.453372 7.327219 HMGB2 1.370593472 0.043453389 0.002821368 37.43681167 3.024504 2.023048 4.285996 8.122528 9.418172 8.25089 LOC155060 1.349375887 0.043453389 0.003093569 37.40064496 4.209882 2.406905 3.324375 8.087444 8.549366 8.579284 HEPH 1.520376076 0.043453389 0.001480095 37.27143751 1.874444 2.023048 2.165421 7.243046 7.627877 6.924055 DDX59 1.215720273 0.043453389 0.005298401 37.27143751 1.874444 2.023048 2.165421 7.243046 7.598264 5.446557 TUBA1B 1.392465316 0.043453389 0.002515141 37.17455237 5.897292 6.03611 5.592916 11.987974 11.113535 10.171703 FAM162A 1.396701727 0.043453389 0.002474311 37.15013347 3.024504 2.023048 2.165421 7.450526 8.2398 7.03218 C1orf52 1.36529979 0.043453389 0.002882613 37.13673373 5.056948 4.80797 6.175931 10.271723 10.655275 10.166824 CKS1B 1.296113072 0.043453389 0.003978224 37.12977239 3.024504 2.023048 3.324375 8.239009 8.916384 6.722123 CCDC120 1.401883397 0.043453389 0.002426676 37.1209054 6.52121 6.670655 5.609945 10.752415 11.73537 12.047569 TC2N 0.983133573 0.043626235 0.012477033 36.93931612 2.993831 2.406905 3.324375 9.417418 8.200916 4.790662 PLRG1 1.255175754 0.043453389 0.004549847 36.84570388 2.201691 3.770995 2.379345 8.974419 7.89473 6.722123 GUCY1A3 1.388682006 0.043453389 0.002576387 36.78649874 3.839948 2.809601 2.165421 8.885299 7.819723 8.010706 FAM92A3 1.47064828 0.043453389 0.001725077 36.75348136 1.874444 2.406905 2.165421 7.36523 8.2398 6.924055 HPS3 1.33182711 0.043453389 0.003345356 36.75348136 1.874444 2.023048 2.165421 7.36523 7.269549 6.051818 MFN1 1.544560552 0.043453389 0.001343995 36.75119175 1.874444 2.023048 2.165421 7.074163 7.56803 7.180104 ROBO1 1.450324623 0.043453389 0.001902007 36.63787738 3.024504 2.023048 2.379345 7.897963 8.055928 7.218312 CYFIP2 0.95368102 0.043857532 0.01372916 36.54786367 1.874444 2.023048 5.389265 7.394225 7.066159 7.36177 LINC00346 1.442118755 0.043453389 0.002010888 36.47119008 1.874444 2.023048 2.379345 6.664985 7.56803 7.36177 CD1D 1.211502008 0.043453389 0.005400476 36.44794275 4.639409 2.023048 2.379345 7.210813 8.181074 8.809543 AKR1B1 1.070898828 0.043516135 0.009210616 36.38805819 5.263699 2.023048 2.995681 7.274575 8.181074 8.503924 DARC 1.073310749 0.043516135 0.009149371 36.2571758 1.874444 3.360637 5.723602 8.540832 6.861783 12.084253 MTDH 1.388662989 0.043453389 0.002583192 36.07183693 5.304463 5.148082 3.935222 10.45838 10.320883 9.363984 CD9 1.38801567 0.043453389 0.002603607 35.98181115 3.819732 3.770995 3.324375 9.761445 8.94019 7.943848 TMBIM4 1.439837927 0.043453389 0.002044913 35.96083631 2.993831 2.023048 2.165421 7.656039 7.191402 7.825039 IFT80 1.302221671 0.043453389 0.003896563 35.96083631 1.874444 2.023048 2.165421 7.748771 7.191402 5.900694 HSPA14 1.402645435 0.043453389 0.002413066 35.85464659 1.874444 2.023048 2.165421 6.396698 7.187136 7.65565 LOC728758 1.388281227 0.043453389 0.002596802 35.85464659 1.874444 2.023048 2.165421 7.631894 7.187136 6.32627 AGXT2L2 1.424490989 0.043453389 0.002187819 35.73757686 1.874444 2.809601 2.165421 7.556937 7.414086 7.033813 RBMXL1 1.240727835 0.043453389 0.004815243 35.72902629 4.963444 2.406905 3.90836 9.067384 9.847551 7.873743 MTERFD3 1.214900368 0.043453389 0.005318816 35.69713784 1.874444 2.023048 3.935222 7.631894 7.440337 7.03218 KIAA0125 1.160531396 0.043453389 0.006604287 35.62445955 1.874444 2.023048 2.165421 7.177844 8.220489 5.106393 MRPL18 1.4076362 0.043453389 0.002331405 35.62231572 4.263463 4.80797 2.995681 9.067384 9.418172 9.570168 OS9 1.40470259 0.043453389 0.00237904 35.61838256 4.309025 5.148082 5.217616 10.508978 10.302633 9.380933 LAGE3 1.197476388 0.043453389 0.005754338 35.56753009 2.201691 2.023048 2.165421 7.856887 7.31791 5.446557 EBAG9 1.181688504 0.043453389 0.00613474 35.56753009 2.201691 2.023048 2.165421 7.36523 7.31791 5.426231 EMCN 1.490643802 0.043453389 0.001588976 35.54561617 1.874444 2.023048 2.165421 6.814118 7.174648 7.611911 MRPL36 1.290651561 0.043453389 0.004046274 35.54561617 1.874444 2.023048 2.165421 7.33564 7.174648 5.874974 ANGPT1 1.198238124 0.043453389 0.005733923 35.54561617 1.874444 2.023048 2.165421 5.320955 7.174648 8.636861 RNF103 1.338680588 0.043453389 0.0032705 35.5380192 3.819732 3.32135 5.018694 9.81605 9.418172 8.472642 AP3M1 1.253406043 0.043453389 0.004563457 35.49321071 7.445608 6.42919 7.481604 10.828761 12.59508 12.699415 CAMLG 1.303984004 0.043453389 0.003848928 35.45367093 1.874444 2.809601 3.764125 7.957464 8.63937 7.180104 KCNIP4-IT1 1.235053693 0.043453389 0.004903709 35.4181279 1.874444 2.406905 2.165421 5.705318 7.440337 7.553321 POMT1 1.406329771 0.043453389 0.00236543 35.40449285 1.874444 2.023048 2.995681 7.70315 7.505595 7.020304 ATP1B1 1.101418348 0.04349335 0.008167404 35.40449285 1.874444 4.351315 4.449894 9.704692 8.402869 7.020304 COL6A6 1.027393674 0.043577906 0.010654644 35.3908917 1.874444 2.023048 3.90836 5.095353 9.053666 7.722406 LOC285768 1.24747431 0.043453389 0.004685948 35.36795892 1.874444 2.023048 2.165421 7.167419 7.598264 5.634184 GK5 1.327377235 0.043453389 0.003474651 35.32740941 8.351337 7.786385 8.418052 12.214229 13.494054 13.790943 RPS20 1.450603522 0.043453389 0.001895202 35.27945205 8.294165 8.544272 8.448127 13.709563 13.588884 13.019276 ZNF695 1.302496366 0.043453389 0.003882953 35.12611544 4.815804 4.413323 2.379345 8.286188 9.547795 9.910841 FLJ12825 1.375548086 0.043453389 0.002766928 34.9969504 3.350997 2.023048 2.165421 7.631894 8.277663 7.152205 CCDC76 1.355625514 0.043453389 0.003032324 34.9969504 1.874444 2.023048 2.165421 6.183122 7.473335 7.152205 PDGFRL 1.181369617 0.043453389 0.006155155 34.9969504 1.874444 2.023048 3.764125 6.396698 9.687973 7.152205 LOC100129480 1.237623153 0.043453389 0.004849268 34.97654884 5.056948 4.351315 6.410545 9.479631 10.475516 10.388357 HPS5 1.049527651 0.043568903 0.009936033 34.9471662 1.874444 2.023048 2.165421 7.210813 7.292524 4.562324 SRP54 1.322374142 0.043453389 0.003542702 34.92649946 1.874444 2.406905 2.379345 8.361545 7.505595 6.195186 SCOC 1.022960332 0.043577906 0.010920041 34.92649946 2.201691 2.406905 2.379345 8.376156 7.505595 4.562324 LOC401397 1.225307567 0.043453389 0.005073835 34.89228003 3.839948 2.023048 2.165421 8.964784 8.055928 6.385515 OBFC2A 1.41910191 0.043453389 0.002201429 34.82012411 2.993831 3.872014 3.324375 8.488001 8.579995 8.11568 COL6A4P2 1.295847045 0.043453389 0.003985029 34.8151922 3.350997 3.872014 2.165421 7.33564 8.682351 8.472642 ZMAT1 1.491876506 0.043453389 0.001568561 34.80098872 1.874444 2.023048 2.379345 7.144104 7.406567 7.020304 TSG1 1.474748257 0.043453389 0.001704661 34.80098872 1.874444 2.023048 2.165421 7.144104 6.794431 7.897492 NQO2 1.203078015 0.043453389 0.005543382 34.80098872 1.874444 2.023048 2.165421 7.144104 7.414086 5.426231 LOC100129917 1.318969079 0.043453389 0.003576727 34.76422937 6.186289 5.297868 4.724406 9.868664 10.589051 10.4174 CYB5R1 1.483421527 0.043453389 0.001657026 34.68414378 1.874444 2.406905 2.165421 7.037879 7.191402 7.523109 AARS2 1.174641158 0.043453389 0.006291256 34.67758039 4.209882 2.023048 2.165421 7.631894 7.138979 7.553321 C7orf23 1.088246078 0.043516135 0.008668935 34.67758039 1.874444 2.023048 2.165421 7.394225 7.138979 4.790662 SCARA5 1.107340416 0.04349335 0.007997278 34.67524504 4.743564 3.32135 3.935222 6.960054 9.991223 9.051056 LRIG1 1.077989902 0.043516135 0.00902688 34.66439245 2.201691 3.32135 5.018694 10.388031 8.436733 6.587378 JTB 1.393284287 0.043453389 0.002508336 34.63221867 4.815804 3.872014 3.935222 9.049264 9.392516 9.040427 PHF20L1 1.344948274 0.043453389 0.003182035 34.53159608 3.350997 4.389936 2.379345 8.460842 8.737737 8.340256 RCOR3 1.459138408 0.043453389 0.001827152 34.51828186 2.993831 2.809601 2.379345 7.450526 7.91889 8.519314 ATF3 1.038416009 0.043577906 0.01035114 34.43362266 3.350997 5.789702 6.410545 11.761857 9.586024 8.456743 C15orf2 1.432012016 0.043453389 0.002119769 34.39503536 1.874444 2.023048 2.165421 6.544171 7.269549 7.152205 UBAC1 1.424572918 0.043453389 0.002181014 34.39503536 2.201691 2.023048 2.165421 7.897963 7.269549 6.618407 GSG1 1.415867287 0.043453389 0.002228649 34.37241972 1.874444 2.023048 2.995681 7.631894 8.098861 6.942983 IRX3 1.018536847 0.043577906 0.011117387 34.37241972 1.874444 3.32135 2.995681 10.034429 8.098861 4.790662 SNX3 1.373035243 0.043453389 0.002807758 34.28193988 4.815804 3.360637 3.764125 9.744652 9.915181 8.32282 DDX1 1.202456456 0.043453389 0.005563797 34.26229035 4.815804 3.32135 2.165421 9.002943 8.4199 7.640338 ULBP1 1.327665772 0.043453389 0.003454236 34.21251151 1.874444 3.770995 3.935222 8.488001 9.031674 7.873743 IMMP1L 1.123339567 0.043453389 0.007475332 34.07953365 2.201691 2.023048 2.379345 8.376156 7.292524 5.091834 HSD17B4 1.408109059 0.043453389 0.0023246 34.05108501 2.201691 2.023048 2.165421 9.08528 7.25505 6.722123 POPDC2 1.310879857 0.043453389 0.003726438 34.05108501 2.201691 2.023048 2.165421 6.063041 7.25505 7.774634 ZC2HC1A 1.484712077 0.043453389 0.001650221 33.97753111 1.874444 2.023048 2.165421 7.109557 6.794431 7.352555 ACBD7 1.383101718 0.043453389 0.002685267 33.97753111 1.874444 2.023048 2.165421 7.109557 7.53715 6.32627 TXLNG2P 1.326574143 0.043453389 0.003495066 33.97753111 1.874444 2.023048 2.165421 7.109557 7.627877 6.051818 MED30 1.069320708 0.043516135 0.009285471 33.95708335 3.839948 2.023048 2.165421 8.925589 7.845161 5.426231 TTTY15 1.409807012 0.043453389 0.002304185 33.95636401 1.874444 2.809601 2.165421 6.960054 7.68534 7.327219 ENPP1 1.192839633 0.043453389 0.005882953 33.937026 1.874444 2.023048 2.379345 8.087444 7.107836 5.446557 SYBU 1.159363995 0.043453389 0.006631507 33.937026 1.874444 2.023048 2.165421 9.137671 7.107836 5.106393 BOLA1 1.148524892 0.043453389 0.006903709 33.937026 1.874444 2.023048 2.165421 7.814607 7.107836 5.091834 DCTN4 1.129596454 0.043453389 0.007352841 33.72497065 3.819732 2.023048 2.379345 8.895478 7.942653 5.874974 TTC14 1.389413666 0.043453389 0.002562776 33.69251979 3.024504 2.406905 2.165421 7.037879 8.098861 7.582913 CWC15 1.208383591 0.043453389 0.005454917 33.62674462 1.874444 2.023048 2.165421 8.955085 7.094585 5.426231 MAP3K1 1.189837508 0.043453389 0.005985029 33.62674462 1.874444 2.023048 2.379345 8.822673 7.094585 5.426231 RAET1E 1.102071727 0.04349335 0.008140184 33.62674462 1.874444 2.023048 2.165421 4.894482 7.094585 7.327219 EIF3M 1.102076061 0.04349335 0.008133379 33.55694331 1.874444 4.830496 2.379345 8.156778 7.91889 6.942983 CUL4B 1.379250948 0.043453389 0.002732902 33.54726746 3.350997 2.023048 2.379345 8.41912 8.033973 7.03218 VEZT 1.487961556 0.043453389 0.001609391 33.48787281 3.819732 3.32135 3.324375 8.885299 8.609988 8.374509 SFRP2 1.199631142 0.043453389 0.005699898 33.4548031 3.839948 2.809601 4.724406 8.206677 10.99919 7.873743 C12orf65 1.1612775 0.043453389 0.006577067 33.40156651 6.924263 6.311907 7.401896 10.084223 11.986107 12.946423 SCARB2 1.36621899 0.043453389 0.002875808 33.39925127 4.963444 4.413323 4.508334 10.025188 9.853832 8.870819 DCTN3 1.177209706 0.043453389 0.006250425 33.36461308 4.309025 5.340619 2.995681 8.925589 8.055928 10.788406 PTPRC 0.96059629 0.043778104 0.01333719 33.33183655 2.993831 3.770995 7.295639 9.939241 8.829823 8.593895 FBXL5 1.230566457 0.043453389 0.004964954 33.30472878 2.993831 2.023048 2.165421 8.051486 7.989035 5.900694 TRO 1.241195316 0.043453389 0.004801633 33.28891815 3.350997 2.023048 2.165421 6.063041 8.385634 8.407967 FREM2 1.391757549 0.043453389 0.002535556 33.2844889 1.874444 2.023048 2.995681 7.394225 8.033973 6.931222 NGRN 1.158756095 0.043453389 0.006645117 33.17148844 3.350997 3.872014 2.995681 9.873821 8.402869 6.587378 C12orf75 1.209762247 0.043453389 0.005434502 33.15408767 1.874444 2.023048 2.165421 7.074163 7.845161 5.446557 ATP5F1 1.275750943 0.043453389 0.00423001 33.1002066 3.024504 2.809601 3.935222 8.98399 8.867558 7.03218 CXCR2P1 1.23926553 0.043453389 0.004835658 33.02284377 1.874444 2.023048 2.165421 7.210813 7.187136 5.634184 SNRNP27 1.356756624 0.043453389 0.002991494 33.02188826 3.839948 3.32135 2.165421 8.885299 8.296229 7.722406 C6orf97 1.446216131 0.043453389 0.001970058 32.99792332 3.024504 3.360637 2.379345 8.40494 7.870158 7.943848 PPP2R3C 1.387584727 0.043453389 0.002624022 32.97066079 1.874444 2.023048 2.165421 7.856887 7.066159 6.385515 FYB 1.363601988 0.043453389 0.002909833 32.97066079 3.024504 2.023048 2.165421 8.801178 7.066159 7.180104 CLK2 1.334545291 0.043453389 0.003304525 32.97066079 1.874444 2.023048 2.165421 7.631894 7.066159 6.106561 TMEM216 1.06054035 0.043540291 0.009532494 32.97066079 1.874444 2.023048 2.165421 7.937902 7.066159 4.562324 MEA1 1.345578521 0.043453389 0.00316162 32.86071323 3.350997 2.809601 2.995681 8.553743 8.033973 7.255535 PPIL4 1.323820648 0.043453389 0.003515481 32.58551088 3.024504 2.406905 3.324375 8.139755 8.350533 7.033813 MYOF 1.052019993 0.043568903 0.009867982 32.54092707 4.639409 3.32135 2.165421 9.663593 8.36819 6.195186 MLKL 1.402090617 0.043453389 0.002419871 32.48530105 1.874444 2.406905 2.165421 6.651882 7.187136 8.175185 ARL3 1.201090601 0.043453389 0.005611432 32.48530105 3.819732 2.023048 2.165421 7.36523 7.187136 7.180104 PRKAR2B 1.152292124 0.043453389 0.006794828 32.42260326 4.815804 2.023048 2.995681 8.014609 7.740604 8.095288 GPR112 1.201497747 0.043453389 0.005591017 32.37079998 2.201691 2.023048 3.935222 7.897963 7.066159 7.218312 VAV3 1.381178359 0.043453389 0.002719292 32.23968258 1.874444 2.023048 2.165421 9.058353 6.551443 7.033813 NDUFB3 1.304711993 0.043453389 0.003828513 32.21071544 3.024504 2.023048 2.165421 6.395481 8.033973 7.748756 ASNSD1 1.359241318 0.043453389 0.002984689 32.20531095 2.201691 2.023048 2.165421 7.504712 7.174648 6.32627 TRAPPC6B 1.116486033 0.043485739 0.007690371 32.20531095 2.201691 2.023048 2.165421 7.33564 7.174648 5.106393 ZNF165 0.973849717 0.043681142 0.01278394 32.20531095 1.874444 2.406905 2.165421 8.033165 7.174648 4.146207 CHTOP 1.110911107 0.043485739 0.007880912 32.20320163 4.815804 2.023048 2.995681 8.628872 8.077554 7.03218 CCDC84 1.326710028 0.043453389 0.003481456 32.18606305 4.639409 3.770995 3.324375 8.779359 8.564762 8.809543 TFG 1.100762898 0.04349335 0.008208234 32.17972436 4.743564 4.80797 2.379345 9.8105 8.055928 8.010706 SSPN 1.310003663 0.043453389 0.003733243 32.14832954 3.839948 2.406905 4.508334 8.105092 9.275744 8.84662 SRP14 1.211610124 0.043453389 0.005386866 32.13004187 5.263699 2.406905 3.935222 9.094145 8.402869 8.941073 LOC285696 1.491817839 0.043453389 0.001575366 32.04434856 2.201691 2.023048 2.165421 7.167419 7.269549 6.924055 EPHX1 1.27375849 0.043453389 0.00424362 32.02049957 4.209882 4.413323 4.944468 8.433162 9.962448 9.414247 TSPYL4 1.356029306 0.043453389 0.003018714 31.93919991 3.024504 2.023048 2.995681 8.895478 7.845161 7.020304 FAM149B1 1.320857343 0.043453389 0.003563117 31.93919991 1.874444 2.023048 2.165421 6.063041 7.269549 7.020304 PART1 1.368688849 0.043453389 0.002848588 31.89391753 6.008206 5.362142 6.175931 10.187245 11.395554 11.003415 SLC50A1 1.382840452 0.043453389 0.002698877 31.87912041 4.815804 3.32135 4.944468 9.359771 9.939008 9.462817 KARS 1.282930243 0.043453389 0.004155155 31.78127145 3.024504 2.023048 3.935222 8.014609 8.2398 7.46072 AKAP9 1.214905317 0.043453389 0.005312011 31.77620768 3.839948 3.360637 5.389265 9.179923 8.829823 8.650903 CLDN12 1.196098343 0.043453389 0.005787683 31.71553571 1.874444 2.023048 3.90836 8.895478 7.107836 6.73963 METTL15 1.187012909 0.043453389 0.006032664 31.70820459 3.819732 2.023048 2.165421 7.037879 7.406567 7.152205 DNAJC15 1.191990207 0.043453389 0.005910174 31.65206094 3.819732 2.809601 2.165421 8.925589 7.793829 6.587378 C1orf123 1.328508052 0.043453389 0.003420211 31.62369838 2.993831 2.406905 3.935222 7.976765 8.4199 7.748756 CNKSR3 1.448262341 0.043453389 0.001929228 31.61880125 1.874444 2.406905 2.165421 6.857154 7.187136 7.352555 HSDL2 1.069268156 0.043516135 0.009292276 31.61253292 4.639409 2.023048 2.379345 7.656039 7.066159 7.36177 CFL1P1 1.220170687 0.043453389 0.00518952 31.56735444 4.639409 2.406905 4.285996 7.726141 9.266358 9.346832 NDUFA4 1.361403149 0.043453389 0.002943858 31.53288055 4.263463 4.830496 4.944468 11.275169 9.809281 8.997112 MGC23270 1.330889548 0.043453389 0.003392991 31.53065789 3.350997 2.406905 2.165421 7.144104 7.713236 7.553321 CACNB2 1.215211839 0.043453389 0.005305206 31.46256022 4.963444 5.297868 3.324375 8.376156 9.939008 9.984774 SF3B1 1.273743468 0.043453389 0.004250425 31.42949639 5.982974 4.389936 5.609945 11.138295 10.527518 9.363984 GNE 1.21272124 0.043453389 0.005359646 31.4199118 4.263463 3.770995 2.165421 9.23707 7.406567 8.305171 HDAC1 1.214654734 0.043453389 0.005325621 31.41884653 2.201691 2.023048 2.165421 7.394225 7.138979 5.634184 IARS2 1.205076227 0.043453389 0.005495747 31.41884653 3.024504 2.023048 2.165421 8.316805 7.138979 6.051818 YBX1 1.37527445 0.043453389 0.002773733 31.29942083 5.056948 4.750708 5.389265 10.561063 10.025012 9.454835 RILPL2 1.313962622 0.043453389 0.003658387 31.26959414 3.839948 2.023048 3.90836 8.875048 8.200916 8.053616 RAB33B 1.133148507 0.043453389 0.007271181 31.22285776 3.024504 3.360637 2.995681 8.925589 7.989035 6.195186 MFN2 1.264116174 0.043453389 0.004379721 31.15626786 3.819732 2.809601 2.165421 7.771052 8.140553 7.218312 DBI 1.056131079 0.043540291 0.00972984 31.09862275 4.743564 4.389936 4.285996 10.650924 9.348715 7.03218 BEND2 1.152357621 0.043453389 0.006788023 31.08883941 2.993831 2.406905 4.944468 7.36523 8.258856 8.997112 UHRF2 1.334885608 0.043453389 0.00329772 30.99408886 1.874444 3.360637 3.764125 7.726141 8.314558 8.32282 NTRK2 1.150755415 0.043453389 0.006849268 30.92098567 2.201691 4.750708 2.995681 9.252991 8.033973 7.152205 LOC100131257 1.38664099 0.043453389 0.002630827 30.9198754 7.067614 6.821329 7.593473 11.725233 12.639383 12.018077 FUCA2 1.126130656 0.043453389 0.007434502 30.82988526 2.201691 2.406905 3.324375 8.270632 8.200916 5.580533 SELE 1.046294498 0.043577906 0.010100034 30.78458253 1.874444 3.360637 2.165421 7.109557 5.165949 9.103055 NBAS 1.244369869 0.043453389 0.004774413 30.74788378 1.874444 2.023048 2.165421 5.705318 7.107836 7.033813 FRZB 1.127406931 0.043453389 0.007407281 30.74788378 1.874444 2.023048 2.165421 5.095353 7.107836 7.020304 ZNF189 1.235415384 0.043453389 0.004890099 30.63280987 1.874444 2.023048 2.165421 6.960054 7.656894 5.634184 ARHGEF6 1.195695111 0.043453389 0.005801293 30.63280987 2.201691 2.023048 3.90836 6.960054 7.269549 7.825039 RICTOR 1.263380463 0.043453389 0.004400136 30.61865727 4.209882 3.360637 2.995681 9.146221 8.436733 7.492252 TMEM198B 0.867447711 0.044369384 0.018025859 30.57924565 2.201691 2.809601 3.324375 7.835902 8.258856 4.146207 NOL10 1.484870677 0.043453389 0.001643416 30.50765727 2.201691 2.023048 2.165421 6.954147 7.25505 7.033813 KIF22 1.345811504 0.043453389 0.003154815 30.50560287 1.874444 2.809601 2.165421 6.544171 7.740604 7.428484 PQLC3 0.894136718 0.044203301 0.016808438 30.46676027 1.874444 2.023048 2.165421 6.960054 7.094585 3.676349 C1orf140 0.771554363 0.046066162 0.02397278 30.46676027 2.201691 2.023048 2.165421 2.820813 7.094585 7.352555 MRPS11 1.304815336 0.043453389 0.003821708 30.27358514 1.874444 3.360637 2.165421 7.814607 6.794431 7.582913 MZT2B 1.140991678 0.043453389 0.00710786 30.27358514 1.874444 3.770995 3.324375 9.367104 6.794431 7.218312 ZNF674 1.301934657 0.043453389 0.003916979 30.1480339 4.309025 4.80797 5.571599 8.955085 10.183015 10.485591 COQ5 1.23175442 0.043453389 0.004937734 30.08567326 2.993831 2.406905 2.379345 8.316805 7.31791 6.32627 MYLK4 1.435288397 0.043453389 0.002078938 30.07069338 1.874444 2.023048 2.379345 7.210813 6.78473 7.020304 SKAP2 1.141876001 0.043453389 0.00705342 30.07069338 1.874444 2.023048 4.285996 8.270632 6.78473 7.255535 TSFM 1.137178136 0.043453389 0.007196325 30.0646308 1.874444 3.360637 2.165421 8.270632 7.094585 5.874974 DLK1 0.9225467 0.044091888 0.015218782 30.03852001 1.874444 2.406905 2.165421 7.074163 8.867558 3.676349 CAT 1.195492807 0.043453389 0.005808098 30.02758475 4.682076 2.809601 3.935222 9.590293 9.198885 7.36177 RPSAP9 1.251028246 0.043453389 0.004604287 30.02669603 1.874444 2.023048 2.165421 5.728038 7.656894 6.931222 BTN2A1 1.200475895 0.043453389 0.005672678 30.02669603 3.819732 2.023048 2.165421 7.814607 7.174648 6.931222 IRX5 1.219657742 0.043453389 0.005209935 30.02014287 3.350997 4.413323 3.324375 9.884081 8.258856 7.582913 PRKAA1 1.288206241 0.043453389 0.004114325 29.90431184 3.024504 2.023048 2.995681 7.897963 8.220489 6.649696 KLHDC1 1.314816514 0.043453389 0.003624362 29.87790531 1.874444 2.023048 2.165421 6.063041 7.627877 6.924055 GTF2H1 1.211573024 0.043453389 0.005393671 29.87790531 3.839948 2.023048 2.165421 8.206677 7.187136 6.924055 DUSP10 1.181364273 0.043453389 0.00616196 29.87233018 2.201691 2.023048 2.165421 8.822673 7.066159 5.426231 KLHL2 1.01285523 0.043581008 0.011361688 29.87233018 2.201691 2.023048 2.165421 7.167419 7.066159 4.562324 HNF1A-AS1 1.452617105 0.043453389 0.001874787 29.86186912 1.874444 2.023048 2.165421 6.857154 6.774676 7.291822 ITFG1 1.194757594 0.043453389 0.005828513 29.8113244 3.839948 2.023048 2.165421 7.210813 8.737737 6.69026 OXA1L 1.360793121 0.043453389 0.002964274 29.79857409 3.350997 3.770995 3.935222 9.755869 8.668166 8.010706 KDM5B 1.126061068 0.043453389 0.007441307 29.74872027 3.839948 2.023048 2.165421 8.734704 7.187136 6.195186 C9orf16 1.26485903 0.043453389 0.004372916 29.72420265 3.024504 4.750708 3.324375 7.918071 8.94019 8.870819 ZNF252 1.326603647 0.043453389 0.003488261 29.56092315 2.201691 2.406905 2.165421 6.339437 7.292524 7.291822 OXCT1 1.014578067 0.043581008 0.011280027 29.52243909 2.993831 2.023048 2.165421 7.877571 7.406567 4.790662 ZNF669 1.327488278 0.043453389 0.003467846 29.44516018 4.309025 4.413323 4.285996 8.460642 9.188984 10.028457 MAL2 1.114360625 0.043485739 0.007778836 29.35846873 2.201691 3.770995 2.379345 9.627408 7.25505 6.106561 PSMD5 1.388001581 0.043453389 0.002610412 29.24717514 3.024504 2.406905 3.324375 7.582358 7.89473 7.943848 MED28 1.090203204 0.043516135 0.00859408 29.13069048 2.201691 2.406905 2.165421 7.814607 7.066159 5.106393 AHNAK 1.305297342 0.043453389 0.003787683 29.08342561 6.554045 7.303362 6.282905 11.41617 12.322489 10.992428 COL3A1 1.067263884 0.043516135 0.009333106 28.9900444 5.700376 7.197097 8.234655 10.557862 13.454821 11.141608 PDCD6 1.311659275 0.043453389 0.003706022 28.93779811 2.201691 3.872014 2.165421 8.579223 8.2398 7.020304 MRPL11 1.258241709 0.043453389 0.004481797 28.93779811 1.874444 2.406905 2.165421 7.897963 5.936219 7.020304 C8orf44 1.282268884 0.043453389 0.00416196 28.91838598 2.201691 2.023048 2.995681 6.395481 7.414086 7.849596 CPNE3 1.22296601 0.043453389 0.005141885 28.86615951 4.309025 3.872014 2.165421 8.723321 8.777924 7.523109 LOC494127 1.178201462 0.043453389 0.006209595 28.80295076 4.263463 2.406905 2.165421 7.177844 7.25505 8.84662 TRIM39 1.441349613 0.043453389 0.002017693 28.79366669 1.874444 2.023048 2.165421 6.814118 7.094585 6.722123 TOP1MT 1.34212424 0.043453389 0.003209255 28.79366669 1.874444 2.809601 2.165421 7.144104 7.292524 6.722123 FOLR1 1.158283711 0.043453389 0.006651922 28.79366669 1.874444 3.872014 2.165421 9.29204 6.774676 6.722123 C1orf126 1.327742062 0.043453389 0.003447431 28.70445443 5.304463 4.830496 3.935222 9.171571 10.147665 9.570168 PAIP1 1.058249399 0.043540291 0.009593739 28.62083171 3.350997 3.770995 2.995681 8.222933 8.609988 6.106561 LOC100131176 1.32954682 0.043453389 0.003413406 28.61570033 1.874444 2.023048 2.165421 7.937902 6.861783 6.195186 C4orf33 1.039027569 0.043577906 0.010330725 28.61570033 1.874444 2.023048 2.165421 8.173604 6.861783 4.476242 SUCLA2 1.30692967 0.043453389 0.003767268 28.52404123 1.874444 2.023048 2.165421 6.857154 7.094585 6.051818 FAM76A 1.201224353 0.043453389 0.005604627 28.52404123 3.839948 2.023048 2.165421 6.857154 7.187136 8.135789 CEP290 1.162996485 0.043453389 0.006536237 28.52404123 3.839948 2.023048 2.165421 6.857154 7.598264 7.020304 FGG 0.803230397 0.045338539 0.021842123 28.52404123 1.874444 2.023048 2.165421 6.857154 7.53715 2.921909 ZNF280D 1.344961563 0.043453389 0.00317523 28.48484659 2.201691 2.406905 3.324375 7.70315 8.098861 7.033813 TTF1 1.191744079 0.043453389 0.005930589 28.46679443 2.993831 4.413323 2.165421 7.748771 7.89473 7.825039 MBOAT1 1.22317861 0.043453389 0.005128275 28.45749028 1.874444 2.809601 4.449894 8.854326 7.627877 7.640338 HSP90AA1 1.292334802 0.043453389 0.004025859 28.36550061 8.313476 8.544272 9.431116 13.483213 14.257181 13.003629 LOC100129316 1.340554031 0.043453389 0.003236475 28.32574051 1.874444 2.023048 2.995681 7.531061 7.819723 6.587378 LOC100507043 1.258204983 0.043453389 0.004488602 28.32574051 2.993831 2.023048 2.995681 6.954147 7.819723 7.033813 SMAGP 1.154275432 0.043453389 0.006740388 28.29142686 1.874444 2.809601 2.165421 7.631894 7.174648 5.580533 POLR1D 1.247452902 0.043453389 0.004692753 28.27757202 5.700376 6.139057 4.724406 10.960644 9.950776 9.808064 SELENBP1 1.302155205 0.043453389 0.003910174 28.24220953 4.639409 4.736586 6.031658 9.45919 10.12707 10.637895 EID1 1.302217304 0.043453389 0.003903368 28.1563887 5.744513 3.872014 6.012527 9.81605 10.827917 10.473789 NOP2 1.224208852 0.043453389 0.00510786 28.14801618 1.874444 2.023048 3.90836 8.723321 7.656894 6.587378 INTS4 1.025871953 0.043577906 0.010736305 28.09141903 1.874444 2.809601 2.379345 4.894482 7.191402 7.695565 CDK11A 1.385874106 0.043453389 0.002637632 28.05059022 3.350997 3.360637 3.324375 9.344992 8.160956 7.849596 C6orf147 1.389243899 0.043453389 0.002569581 28.00846712 1.874444 2.023048 2.379345 6.544171 7.187136 7.020304 UBE2A 1.336013022 0.043453389 0.00328411 27.92504731 2.201691 3.32135 3.90636 8.711848 7.989035 7.920656 LOC145216 1.295275515 0.043453389 0.004005444 27.89537618 5.491121 4.911517 5.702912 9.403221 10.732294 10.293075 AP3S1 1.185039382 0.043453389 0.006059884 27.84645718 3.839948 2.406905 2.379345 7.856667 8.63937 6.455366 C8orf83 1.266030782 0.043453389 0.004359306 27.8286526 1.874444 2.023048 2.379345 7.177844 7.174648 5.900694 TERF1 1.318635193 0.043453389 0.003597142 27.81396266 3.819732 2.809601 3.324375 7.607339 8.533804 8.155622 CUL1 1.336475973 0.043453389 0.003277305 27.7705281 1.874444 2.809601 3.324375 7.33564 8.119657 7.46072 NEXN 1.19780668 0.043453389 0.005740728 27.75417262 1.874444 2.809601 2.165421 6.960054 7.819723 5.900694 UBE2V2 1.016211074 0.043581008 0.011205172 27.75417262 2.201691 2.023048 2.165421 6.960054 7.414086 4.562324 CHMP5 1.262148716 0.043453389 0.004440966 27.70487106 4.639409 3.32135 4.449894 9.431477 8.668166 8.456743 HIBCH 1.408205581 0.043453389 0.002317795 27.67558528 1.874444 2.023048 2.165421 6.664965 7.473335 6.722123 LOC151475 1.285672205 0.043453389 0.004127935 27.67558528 1.874444 3.360637 2.165421 6.664965 7.942653 7.523109 KIAA0922 1.200724007 0.043453389 0.005645458 27.67558528 1.874444 2.023048 3.764125 6.664965 7.440337 7.611911 CACYBP 1.31956748 0.043453389 0.003569922 27.64478389 6.45321 6.572071 6.83141 10.70401 11.620345 11.57626 PHLDA3 1.205863977 0.043453389 0.005482137 27.6407809 2.201691 2.023048 2.165421 6.954147 7.473335 5.634184 PCDHB9 1.410768292 0.043453389 0.002290575 27.63248235 1.874444 2.023048 2.165421 6.811341 6.640994 7.668215 ALG6 1.394775296 0.043453389 0.002494726 27.63248235 1.874444 2.023048 2.379345 6.811341 7.066159 6.69026 SMARCAD1 1.304513855 0.043453389 0.003842123 27.63248235 1.874444 2.023048 2.165421 6.811341 7.138979 6.051818 MCEE 1.184678753 0.043453389 0.006066689 27.63248235 1.874444 2.023048 2.165421 6.811341 7.414066 5.426231 GULP1 0.781133439 0.045799831 0.023259612 27.63248235 1.874444 2.023048 2.379345 6.811341 7.440337 5.921909 DYNC1I2 1.327615653 0.043453389 0.003461041 27.58807888 5.658609 5.297868 4.754917 10.444562 10.006216 9.570168 PHAX 1.243471647 0.043453389 0.004781218 27.54026237 5.316227 4.911517 3.935222 8.723321 9.694987 9.769968 CAGE1 1.20359799 0.043453389 0.005522967 27.52617776 3.839948 2.406905 2.165421 6.252746 8.609988 8.622681 ADH4 1.389436138 0.043453389 0.002555971 27.42536243 1.874444 2.023048 2.165421 6.651882 8.055928 6.73963 COX5A 1.203328515 0.043453389 0.005529772 27.41727934 4.309025 3.872014 4.724406 10.91884 9.086038 7.873743 TMEM131 1.316177849 0.043453389 0.003610752 27.38383058 1.874444 2.023048 3.324375 7.976765 7.793829 6.649696 CHD1L 1.395319453 0.043453389 0.002487921 27.34488431 1.874444 2.406905 2.379345 6.960054 6.861783 7.180104 KCNS3 1.333010474 0.043453389 0.003331745 27.31049112 1.874444 2.023048 2.165421 7.144104 6.794431 6.195186 VPS37A 1.331793484 0.043453389 0.003352161 27.31049112 1.874444 2.023048 2.165421 7.36523 6.794431 6.195186 ITPKB 1.267570998 0.043453389 0.004325281 27.31049112 2.993831 2.023048 2.995681 8.156778 6.794431 7.291822 TP53INP1 1.212479915 0.043453389 0.005366451 27.31049112 2.993831 2.023048 3.764125 8.069577 6.794431 8.053616 C3orf75 1.185333178 0.043453389 0.006053079 27.31049112 1.874444 2.023048 2.165421 7.607339 6.794431 5.426231 PTH1R 1.048036445 0.043577906 0.010018374 27.31049112 1.874444 2.023048 2.165421 4.718672 6.794431 7.020304 CD2AP 1.292672349 0.043453389 0.004019054 27.27154382 3.024504 2.406905 3.324375 9.704692 7.793829 7.033813 C7orf53 1.186350694 0.043453389 0.006039469 27.21916211 1.874444 2.406905 4.508334 8.757204 6.640994 8.650903 CYB5RL 1.302765953 0.043453389 0.003862538 27.21082387 4.963444 4.351315 3.935222 8.540832 9.729553 9.414247 SEPT1 1.392275523 0.043453389 0.002521946 27.20501672 2.201691 2.023048 2.165421 7.70315 6.613395 6.931222 TENC1 1.318863278 0.043453389 0.003583532 27.18396073 3.350997 2.406905 3.935222 7.771052 8.564762 8.11568 BCAS2 1.412430196 0.043453389 0.002262674 27.12745785 1.874444 2.023048 2.165421 7.36523 6.78473 6.618407 SLC25A20 1.302507789 0.043453389 0.003876148 27.12745785 1.874444 2.023048 2.165421 7.109557 6.78473 6.51818 C2orf67 1.288782249 0.043453389 0.004073494 27.12745785 3.024504 2.023048 2.165421 6.960054 6.78473 7.291822 CGNL1 1.239415644 0.043453389 0.004828853 27.12745785 1.874444 2.023048 2.995681 8.801178 6.78473 6.385515 MRPL9 1.221641844 0.043453389 0.005169105 27.12745785 1.874444 2.023048 2.165421 7.394225 6.78473 5.634184 CAPZA2 1.251008609 0.043453389 0.004611092 27.11795784 3.350997 4.736586 3.935222 9.220972 8.696398 8.135789 C15orf29 1.267254291 0.043453389 0.004338891 27.08898184 1.874444 2.406905 2.379345 8.301578 7.138979 6.051818 D2HGDH 1.236465647 0.043453389 0.004862879 27.08898184 1.874444 2.406905 2.379345 7.531061 7.138979 5.900694 TIA1 1.246571093 0.043453389 0.004719973 27.07231286 3.839948 4.389936 3.935222 9.137671 9.148683 7.774634 MRPS33 1.324974146 0.043453389 0.003501871 27.07020821 1.874444 2.406905 2.165421 6.339437 7.187136 6.924055 ARAF 1.20305 0.043453389 0.005550187 27.00097964 2.993831 3.872014 2.165421 7.748771 7.094585 7.800057 NEK5 1.279086825 0.043453389 0.004195985 26.93930149 5.491121 4.351315 5.018694 9.102956 10.779249 9.649245 GFM2 1.312923887 0.043453389 0.003678802 26.93907272 1.874444 2.023048 2.165421 7.074163 6.774676 6.106561 MYO9A 1.304878008 0.043453389 0.003814903 26.93907272 1.874444 2.023048 2.165421 6.067497 6.774676 7.352555 PIGB 1.268381405 0.043453389 0.004304866 26.93907272 1.874444 2.023048 2.165421 7.30543 6.774676 5.882028 ENOPH1 0.908376858 0.044173537 0.015981626 26.93907272 1.874444 2.023048 2.165421 8.033165 6.774676 3.630092 EFNA4 0.879435185 0.044278935 0.017476693 26.93907272 1.874444 2.023048 2.165421 7.109557 6.774676 3.630092 SYPL1 1.198475456 0.043453389 0.005720313 26.86521477 5.700376 4.389936 4.449894 10.448044 9.266358 8.784285 CHPT1 1.210262053 0.043453389 0.005420891 26.85520033 4.209882 3.360637 3.935222 10.746803 8.682351 7.428484 LOC100128292 1.322332238 0.043453389 0.003549507 26.83698597 4.963444 3.360637 4.944468 8.993498 9.694987 9.690619 KLHL20 1.33934312 0.043453389 0.003250085 26.7963288 1.874444 2.023048 2.379345 8.270632 6.640994 6.618407 GLB1 1.258683321 0.043453389 0.004474991 26.7776453 3.024504 2.023048 2.165421 7.726141 7.767462 6.195186 CAPN6 1.104637166 0.04349335 0.008058523 26.74675975 2.201691 2.023048 3.324375 5.728038 9.749902 6.942983 PCBP1 1.158269909 0.043453389 0.006658727 26.71527101 6.099991 5.487673 6.056062 11.549452 10.795655 9.113234 LRRC70 1.143404665 0.043453389 0.007019394 26.7034022 1.874444 2.023048 3.764125 7.274575 6.613395 7.033813 PPL 1.187302315 0.043453389 0.006019054 26.62256564 1.874444 3.32135 3.324375 8.087444 8.055928 6.455366 SRBD1 1.410076224 0.043453389 0.00229738 26.60421067 1.874444 2.023048 2.165421 7.144104 6.608026 6.73963 BCL11B 0.853806804 0.044464174 0.018663491 26.60421067 1.874444 2.406905 5.702912 7.167419 6.608026 7.640338 MPPED2 1.288231932 0.043453389 0.00410752 26.52959835 2.201691 2.406905 2.165421 6.252746 7.596264 6.931222 NDUFAF4 1.225280207 0.043453389 0.00508064 26.43270033 3.024504 3.770995 2.165421 7.037879 8.098861 7.748756 TCP1 1.294560006 0.043453389 0.004012249 26.35673733 6.054828 6.184248 6.891005 10.998912 11.611105 10.591321 IFI27L1 1.344183329 0.043453389 0.00318884 26.29255667 1.874444 2.023048 2.165421 6.339437 7.819723 6.73963 ZNF204P 1.190536984 0.043453389 0.005971419 26.2681036 1.874444 2.023048 2.379345 5.579836 7.094585 6.931222 DUSP16 0.808288261 0.045257569 0.021494386 26.2681036 4.263463 2.023048 2.379345 9.171571 7.094585 4.146207 SUB1 1.169061275 0.043453389 0.006454576 26.26664559 5.700376 5.487673 3.90836 11.207333 10.202833 8.456743 TPM1 1.191107633 0.043453389 0.005951004 26.25449514 5.263699 6.184248 3.324375 10.898741 9.834907 9.113234 FANCD2 1.297734103 0.043453389 0.003971419 26.24490192 3.839948 3.360637 2.165421 7.556937 8.533804 8.074602 TMEM200B 1.0933647 0.04349335 0.00847363 26.22615433 1.874444 2.023048 3.90836 7.274575 6.78473 6.587378 GBP2 1.355447985 0.043453389 0.003039129 26.19997746 4.263463 3.360637 4.754917 9.381659 8.916384 8.974957 F10 1.122974473 0.043480953 0.007514801 26.16558154 2.201691 4.351315 3.324375 6.664985 8.033973 9.584871 NRBP2 1.043836521 0.043577906 0.010215039 26.16230076 3.839948 2.406905 5.225216 8.628872 8.549366 7.291822 C3orf58 1.130842011 0.043453389 0.007325621 26.08107487 3.350997 2.406905 2.995681 7.835902 8.055928 6.106561 CXCL2 1.06489746 0.043516135 0.009394352 26.03931406 3.350997 5.297868 5.225216 11.153218 8.63937 8.053616 PTRHD1 1.201607749 0.043453389 0.005577407 26.02333161 2.993831 2.809601 4.449894 8.98399 7.656894 7.695565 CEP85L 1.166244188 0.043453389 0.006488602 25.97542296 2.201691 2.023048 3.935222 7.33564 7.793829 6.722123 SLC25A12 1.276421753 0.043453389 0.004223205 25.9266156 2.993831 2.023048 2.165421 6.664985 6.861783 7.695565 BCL11A 1.252313386 0.043453389 0.004583872 25.9266156 2.201691 2.023048 2.165421 9.388882 6.861783 6.051818 C14orf45 1.245184011 0.043453389 0.004740388 25.9266156 2.201691 2.023048 2.165421 7.33564 6.861783 5.874974 AK5 1.235847176 0.043453389 0.004883294 25.9266156 1.874444 2.406905 2.165421 8.270632 6.861783 5.900694 DUSP12 0.887282254 0.044203301 0.01714869 25.9266156 1.874444 3.32135 2.165421 8.579223 6.861783 4.146207 RB1CC1 1.228300107 0.043453389 0.005019394 25.90081669 3.819732 4.413323 2.379345 8.514658 8.668166 7.774634 TRPT1 1.27393932 0.043453389 0.004236815 25.84356993 2.201691 3.32135 2.165421 6.857154 7.138979 7.943848 CDC123 1.002153052 0.043588662 0.011776114 25.84356993 2.201691 4.80797 2.165421 6.857154 7.767462 7.020304 SKP1 1.212824281 0.043453389 0.005352841 25.74697466 4.682076 4.80797 3.324375 10.224057 9.228189 8.010706 SATB1 1.092761889 0.04349335 0.008500851 25.69536742 1.874444 3.360637 3.90836 8.591796 7.138979 6.722123 LOC439990 1.040800583 0.043577906 0.010276284 25.65776815 3.350997 2.406905 5.018694 7.177844 8.2398 8.03232 SP100 1.311890328 0.043453389 0.003692412 25.59872008 5.328526 4.389936 4.508334 10.006526 9.81573 8.894619 TAGAP 1.377341913 0.043453389 0.002753317 25.5809718 1.874444 2.023048 2.165421 7.70315 6.551443 6.69026 WDR11 1.373235057 0.043453389 0.002800953 25.5809718 1.874444 2.023048 2.165421 7.835902 6.551443 6.69026 ICOS 1.091663323 0.0435113 0.008552569 25.5809718 1.874444 2.023048 4.285996 7.748771 6.551443 7.255535 MAPKAPK5 1.262296109 0.043453389 0.004434161 25.56761687 1.874444 2.023048 3.324375 6.550689 7.56803 7.46072 NUDT2 1.391350895 0.043453389 0.002542361 25.55468098 1.874444 2.023048 2.165421 6.651882 6.549959 6.942983 LOC440704 1.14382507 0.043453389 0.007005784 25.45236756 1.874444 2.023048 4.449894 6.544171 8.258856 8.03232 INO80B 1.269804049 0.043453389 0.004277645 25.40802313 2.993831 2.023048 2.165421 7.995811 6.774676 6.69026 COL21A1 1.060703985 0.043540291 0.009518884 25.40802313 1.874444 2.023048 2.165421 4.739845 7.627877 6.69026 GUCY1A2 1.342706111 0.043453389 0.003195645 25.34683046 3.350997 2.809601 3.324375 7.976765 7.473335 8.074602 GTF2A2 1.178175253 0.043453389 0.0062164 25.34470702 3.350997 4.389936 2.379345 8.014609 8.436733 7.395512 KDM3B 0.992371271 0.043626235 0.012109561 25.33506092 2.993831 2.809601 3.324375 8.156778 7.656894 5.446557 SNHG13 1.054233315 0.043568903 0.009786322 25.28293607 2.201691 2.023048 3.324375 8.688623 6.861783 5.446557 EXOC1 1.269905002 0.043453389 0.00427084 25.26824784 1.874444 2.406905 2.995681 7.177844 7.066159 6.69026 PLA2G16 1.252695268 0.043453389 0.004577067 25.18457649 3.024504 3.32135 2.379345 8.616619 7.31791 7.033813 CTSF 1.195993532 0.043453389 0.005794488 25.13083076 3.350997 5.297868 5.018694 8.447068 9.81573 9.67008 FTO 1.057854852 0.043540291 0.00963457 25.12617097 5.335413 2.809601 2.995681 8.757204 8.011679 7.46072 IFT43 1.154193206 0.043453389 0.006753998 25.12483103 4.639409 3.360637 2.379345 8.361545 8.011679 7.582913 C4orf43 1.400491226 0.043453389 0.002440286 25.08403735 2.201691 2.023048 2.165421 6.814118 7.138979 6.649696 ABCB7 1.225878698 0.043453389 0.005046614 25.08403735 1.874444 2.406905 6.165421 6.814118 7.066159 5.882028 HIST1H2BD 1.173051353 0.043453389 0.006318476 25.08403735 1.874444 2.023048 2.165421 6.814118 6.774676 5.446557 LARS 1.261372601 0.043453389 0.004454576 25.05974983 4.743564 3.872014 2.995681 8.811966 8.453372 8.519314 EBNA1BP2 1.182228211 0.043453389 0.00612113 24.96189192 3.350997 2.023048 3.324375 9.16317 7.96603 6.32627 OXSR1 1.172615583 0.043453389 0.006332086 24.94924674 2.993831 2.809601 2.379345 7.450526 8.098861 6.129407 BAG1 1.152218936 0.043453389 0.006801633 24.79874847 2.201691 3.360637 2.995681 8.514658 7.627877 6.195186 NDUFB6 1.273549571 0.043453389 0.00425723 24.79322335 3.839948 3.770995 3.324375 8.723321 8.402869 7.582913 SLC9A3R2 1.258137486 0.043453389 0.004495407 24.78739546 3.024504 3.770995 2.379345 7.656039 7.870158 7.428484 NCDN 1.268437083 0.043453389 0.004298061 24.74405998 1.874444 2.406905 2.165421 7.074163 6.794431 6.106561 LACTB2 1.193060818 0.043453389 0.005869343 24.74405998 2.201691 2.023048 2.165421 7.25991 6.794431 5.634184 LSM6 1.101421926 0.04349335 0.008160599 24.74405998 1.874444 2.406905 2.165421 8.376156 6.794431 5.106393 C3orf14 1.098911998 0.04349335 0.008235454 24.74405998 1.874444 2.406905 2.165421 8.033165 6.794431 5.106393 KRCC1 1.35182118 0.043453389 0.003059544 24.7410445 1.874444 2.023048 2.379345 6.651882 6.551443 6.931222 ZNF639 1.288369293 0.043453389 0.004093909 24.7410445 2.201691 2.023048 2.995681 6.651882 7.187136 7.218312 BTN3A1 1.149993582 0.043453389 0.006862879 24.7410445 2.201691 2.023048 4.724406 6.651882 8.668166 8.519314 NADKD1 1.204650513 0.043453389 0.005502552 24.71535693 3.819732 2.406905 2.379345 8.447068 7.292524 6.924055 LZTFL1 1.322482116 0.043453389 0.003529092 24.70357767 1.874444 2.023048 2.165421 8.433162 6.373501 6.649696 GLUD2 1.318825257 0.043453389 0.003590337 24.70357767 1.874444 2.023048 2.165421 7.394225 6.205902 6.649696 PLXDC2 1.26491987 0.043453389 0.004366111 24.70357767 1.874444 2.023048 2.165421 7.42265 5.920411 6.649696 KBTBD6 1.028182814 0.043577906 0.010627424 24.70357767 4.682076 2.023048 2.165421 7.771052 7.25505 6.649696 JPX 1.000944502 0.043588662 0.01182375 24.61500587 4.682076 4.830496 4.285996 7.037879 9.303543 9.676959 ANKHD1 1.092120533 0.0435113 0.008532154 24.6122067 1.874444 3.32135 3.935222 9.276547 7.942653 6.106561 IGSF10 1.088869818 0.043516135 0.008641715 24.59580057 1.874444 3.770995 3.90836 6.063041 9.809281 8.391335 SMYD3 1.370998938 0.043453389 0.002814563 24.57822677 2.201691 2.023048 2.165421 6.550689 6.78473 7.395512 KIAA1598 1.229811105 0.043453389 0.004978564 24.57822677 1.874444 2.809601 2.165421 7.582358 6.78473 6.195186 CC2D2B 1.225940584 0.043453389 0.005039809 24.57822677 1.874444 2.023048 2.165421 5.728038 6.78473 6.722123 PAN2 1.113940659 0.043485739 0.007785641 24.57822677 1.874444 2.809601 2.165421 8.579223 6.78473 5.446557 FGF5 1.046443307 0.043577906 0.010079619 24.57822677 1.874444 2.809601 2.165421 5.095353 6.78473 7.523109 ZNF511 0.730238727 0.047384624 0.027087445 24.57822677 2.993831 2.023048 2.165421 7.937902 6.78473 2.921909 RBL2 1.011402059 0.043581008 0.011395713 24.5606664 5.744513 3.770995 3.324375 8.474485 7.942653 8.549611 ZDHHC1 1.347018693 0.043453389 0.003127594 24.5550265 1.874444 2.023048 2.165421 6.811341 6.640994 6.32627 RSBN1L 1.252956716 0.043453389 0.004570262 24.5550265 1.874444 2.023048 2.165421 6.814118 6.640994 5.874974 FTSJ1 1.234877871 0.043453389 0.004910514 24.5550265 1.874444 2.023048 2.379345 7.167419 6.640994 5.900694 CXorf56 1.20881455 0.043453389 0.005448112 24.5550265 1.874444 2.023048 2.165421 7.074163 6.640994 5.634184 GRHL1 0.893155154 0.044203301 0.016856073 24.5550265 1.874444 2.023048 2.165421 7.748771 6.640994 3.630092 SNX1 1.156859925 0.043453389 0.006692753 24.54898272 3.819732 4.413323 2.379345 9.030914 8.011679 7.428484 SNCA 0.964307712 0.043778104 0.013187479 24.53129473 1.874444 3.32135 2.165421 7.937902 7.53715 4.562324 SKIL 0.884512322 0.044203301 0.017237155 24.52866177 4.209882 4.750708 7.794136 9.367104 9.687973 9.248674 ECHDC2 1.226139953 0.043453389 0.005033004 24.50006535 2.993831 4.911517 6.012527 9.52623 9.275744 10.531856 DNAJC1 1.22334731 0.043453389 0.00512147 24.44821815 1.874444 2.406905 2.995681 7.607339 7.505595 6.129407 LRRCC1 1.314195332 0.043453389 0.003631167 24.40754464 2.201691 2.023048 2.165421 6.252746 6.774676 6.924055 PPP1R21 1.194302362 0.043453389 0.005835318 24.40754464 2.201691 2.023048 2.165421 7.771052 6.774676 5.634184 SEPT7 1.135413648 0.043453389 0.00723035 24.34669689 6.344798 4.830496 4.724406 9.33006 9.532216 9.910841 FAM84A 0.988776416 0.043626235 0.012232052 24.32697642 2.201691 2.809601 4.944468 7.450526 7.414086 7.152205 IL7R 1.117427596 0.043485739 0.007656346 24.27757762 2.201691 4.911517 4.449894 9.513069 7.656894 8.549611 PARP3 1.245668254 0.043453389 0.004733583 24.21014158 1.874444 3.32135 2.995681 7.243046 7.91889 7.020304 CLUAP1 1.159695681 0.043453389 0.006624702 24.20051978 2.201691 2.809601 2.165421 5.705318 7.406567 7.395512 EIF2B1 1.33114887 0.043453389 0.003379381 24.17357893 1.874444 2.023048 2.165421 6.283686 7.31791 6.618407 MUC22 1.327998933 0.043453389 0.003433821 24.17357893 1.874444 2.023048 2.165421 6.244586 6.774676 6.618407 CSTA 1.283373611 0.043453389 0.00414835 24.17357893 1.874444 2.023048 2.165421 6.063041 7.740604 6.618407 C3orf72 1.228707434 0.043453389 0.004992174 24.17357893 2.201691 2.023048 3.764125 7.748771 8.200916 6.618407 ALDH5A1 1.183001358 0.043453389 0.006100715 24.17357893 1.874444 2.023048 3.324375 6.498222 7.656894 6.618407 OTUD1 1.089180811 0.043516135 0.008628105 24.17357893 3.350997 2.023048 4.285996 8.270632 8.055928 6.618407 SLC15A2 1.113022627 0.043485739 0.007819667 24.11160572 3.350997 2.809601 5.018694 7.856887 7.942653 8.472642 LINC00173 1.330363199 0.043453389 0.003399796 24.08974772 1.874444 2.023048 2.185421 6.283686 6.613395 7.327219 LOC338799 1.131234123 0.043453389 0.007312011 24.08974772 4.209882 2.023048 2.379345 7.582358 6.613395 8.11568 LOC100506783 1.06676176 0.043516135 0.009353522 24.08974772 1.874444 2.023048 2.165421 4.894482 6.613395 6.931222 KLHL5 1.161614437 0.043453389 0.006563457 24.06893827 6.417969 4.750708 5.225216 9.3744 10.573912 9.814317 RECQL 1.213446908 0.043453389 0.005346036 24.05937003 2.993831 3.32135 2.379345 7.582358 7.942653 6.649696 CCDC82 1.196942975 0.043453389 0.005774073 24.05937003 2.993831 2.023048 2.165421 7.582358 7.094585 6.051818 SARNP 1.351167297 0.043453389 0.003073154 24.03537901 4.209882 4.736586 4.285996 9.120418 9.294336 8.79697 C1orf133 1.174488081 0.043453389 0.006304866 24.00026479 1.874444 2.023048 2.165421 7.531061 6.608026 5.446557 HSPB11 1.027331267 0.043577906 0.01067506 24.00026479 1.874444 2.023048 2.165421 8.676869 6.608026 4.476242 CDKN2AIPNL 1.262796542 0.043453389 0.004420551 23.97088779 2.201691 3.360637 2.16421 6.550689 7.656894 7.943848 HEXB 1.200598886 0.043453389 0.005659068 23.96802366 2.201691 2.406905 2.165421 8.239009 6.78473 5.874974 SIKE1 1.224561602 0.043453389 0.005101055 23.93288639 1.874444 3.32135 2.165421 7.109557 7.870158 6.455366 RBM15 1.104539406 0.04349335 0.008065328 23.93288639 1.874444 2.023048 3.764125 7.167419 6.861783 6.455366 ZNF10 0.94699911 0.043900827 0.014042191 23.93288639 1.874444 2.023048 4.944468 7.36523 7.138979 6.455366 TTC33 1.037372085 0.043577906 0.010371555 23.92934054 1.874444 2.023048 2.379345 6.960054 6.794431 4.790662 KCNQ1OT1 1.188493591 0.043453389 0.005998639 23.87464806 6.48761 6.049721 6.800663 9.99237 12.049044 11.065018 KLRD1 1.333603849 0.043453389 0.00332494 23.8631422 4.815804 4.351315 4.724406 9.188227 9.392516 8.974957 SERPING1 1.077117872 0.043516135 0.009047295 23.83575652 5.316227 5.661685 5.592916 8.331873 10.167971 11.441372 C5orf56 1.156360275 0.043453389 0.006706363 23.80157906 2.201691 2.809601 2.165421 7.631894 6.774676 5.874974 KIAA1109 1.369955735 0.043453389 0.002834978 23.7910824 3.024504 2.809601 2.995681 7.607339 7.56803 7.352555 SYNE1 1.142927948 0.043453389 0.007033004 23.75822255 3.819732 2.023048 3.324375 6.664985 7.89473 8.053616 LOC100233209 1.288443668 0.043453389 0.004087104 23.74413357 6.792865 6.391145 7.462086 10.960644 11.961598 11.981038 METTL21A 1.217985065 0.043453389 0.005243961 23.68699744 4.309025 5.487673 4.724406 8.875048 9.451686 9.430619 MRPL13 1.356059366 0.043453389 0.003011909 23.65921155 1.874444 2.023048 2.165421 6.396608 6.78473 6.587378 PAAF1 1.289259813 0.043453389 0.004066689 23.65921155 1.874444 2.023048 2.165421 6.067497 6.794431 6.587378 TBC1D7 1.280406093 0.043453389 0.00417557 23.65921155 1.874444 2.023048 2.165421 7.504712 6.043524 6.587378 TRIM66 1.268142789 0.043453389 0.004311671 23.65921155 3.024504 2.023048 2.165421 7.109557 7.191402 6.587378 GPR89A 1.248674399 0.043453389 0.004665532 23.65921155 1.874444 2.023048 2.165421 5.891233 7.845161 6.587378 HDAC11 1.179513077 0.043453389 0.006182375 23.65921155 3.350997 2.023048 2.165421 6.811341 7.174648 6.587378 CRIPT 1.171066747 0.043453389 0.006393331 23.65921155 2.993831 2.023048 3.324375 8.206677 7.066159 6.587378 GPR155 1.281341803 0.043453389 0.004168765 23.62953761 3.839948 4.389936 3.90836 8.139755 8.579995 8.952456 MED18 1.151729621 0.043453389 0.006828853 23.60885295 1.874444 2.023048 2.995681 7.556937 5.936219 6.587378 GLT8D2 0.957806402 0.043835088 0.013535216 23.56230868 3.024504 2.809601 3.90836 5.448591 9.44338 7.582913 TMSB10 1.263616916 0.043453389 0.004386526 23.54320638 7.730559 8.526827 8.589765 12.223349 13.084066 13.815308 CEP120 1.231317893 0.043453389 0.004958149 23.53445132 2.993831 2.023048 2.165421 6.664985 6.861783 6.722123 GUSBP3 1.095976136 0.04349335 0.00836475 23.53445132 1.874444 2.023048 2.165421 5.095353 6.608026 6.722123 LOC649395 0.889163887 0.044203301 0.01705342 23.52035554 6.736762 7.440099 6.737132 12.140187 11.292969 8.822008 PLOD2 1.263438737 0.043453389 0.004393331 23.4558644 3.024504 3.32135 2.379345 8.270632 7.56803 6.931222 KCNJ5 0.904184544 0.044173537 0.016219803 23.4558644 1.874444 2.023048 2.379345 4.013424 6.640994 6.931222 SPG11 1.021646357 0.043577906 0.010960871 23.40601888 3.819732 3.32135 2.995681 8.433162 7.870158 6.051818 KIF20B 1.087081501 0.043516135 0.008709765 23.39534754 3.839948 2.023048 4.449894 6.811341 8.998044 8.194487 LOC646999 1.152033513 0.043453389 0.006822048 23.36181394 4.263463 2.809601 2.995681 6.814118 8.181074 8.809543 MTIF2 1.145688081 0.043453389 0.006951344 23.3171432 2.993831 4.351315 2.165421 7.792994 7.53715 7.492252 PSMA2 1.126665995 0.043453389 0.007427696 23.2475319 5.700376 4.736586 5.217616 10.325413 9.756621 8.519314 KTN1 1.097868094 0.04349335 0.008269479 23.23777193 5.856559 4.389936 3.90836 10.515592 8.928336 8.269212 H6PD 0.816997509 0.045162628 0.020899626 23.21289741 6.58615 3.360637 2.379345 7.30543 8.220489 7.897492 DPCD 1.224892697 0.043453389 0.005087445 23.18917468 1.874444 2.023048 2.995681 7.531061 7.094585 6.129407 LOC100507463 1.268755891 0.043453389 0.004291256 23.16947987 4.743564 4.736586 5.592916 9.220972 10.12707 9.50208 DFNB59 1.248884911 0.043453389 0.004658727 23.07717768 1.874444 2.023048 2.165421 6.811341 6.551443 5.882028 ALAS1 1.171121886 0.043453389 0.006386526 23.07717768 3.819732 2.023048 2.379345 7.976765 6.551443 7.46072 WDR76 1.141200772 0.043453389 0.00709425 23.07717768 1.874444 2.023048 2.165421 5.320955 6.551443 6.942983 VTCN1 1.035607373 0.043577906 0.010398775 23.07717768 1.874444 2.023048 2.165421 8.723321 6.551443 4.562324 ATP13A5 0.949172623 0.043900827 0.013919701 23.07717768 1.874444 2.023048 2.165421 7.243046 6.551443 4.146207 GCNT2 0.902248155 0.044190907 0.016357945 23.07717768 1.874444 2.023048 2.165421 8.069577 6.551443 3.676249 MAP7D3 1.140714523 0.043453389 0.00712147 23.06512989 3.819732 2.023048 2.995681 6.550689 7.53715 8.25089 PDE5A 1.302298759 0.043453389 0.003889758 23.06171826 3.350997 2.023048 2.995681 7.450526 7.56803 7.523109 CNTLN 1.1521129 0.043453389 0.006815243 23.06171826 3.024504 2.809601 2.995681 6.283686 7.845161 7.523109 PDIA5 1.18414961 0.043453389 0.006080299 23.05346013 1.874444 2.023048 2.165421 8.768324 6.549959 5.580533 TMEM156 1.140719187 0.043453389 0.007114665 23.05346013 1.874444 2.023048 5.165421 5.320955 6.549959 6.924055 MTRNR2L6 1.113511115 0.043485739 0.007799251 23.05346013 1.874444 2.023048 2.165421 9.002943 6.549959 5.106393 PTPN22 1.110853583 0.043485739 0.007887717 23.05346013 1.874444 2.023048 2.165421 7.877571 6.549959 5.091834 RNF141 1.107560434 0.043485739 0.007976182 23.05346013 1.874444 2.023048 2.165421 7.450526 6.549959 5.091834 C14orf133 0.939895687 0.043955231 0.014385846 23.05346013 1.874444 2.023048 2.165421 6.954147 6.549959 4.146207 TCEAL3 0.783262576 0.045695042 0.023084723 23.05346013 1.874444 2.023048 2.165421 7.42265 6.549959 2.921909 DHX29 1.209878241 0.043453389 0.005427696 23.02037138 3.819732 2.406905 2.165421 7.957464 7.845161 6.69026 CMAHP 1.193224533 0.043453389 0.005862538 23.02037138 2.201691 3.32135 2.165421 7.30543 6.774676 6.69026 PCDHA9 1.250634511 0.043453389 0.004624702 23.00396157 2.993831 3.32135 2.995681 6.954147 7.845161 7.774634 PPP1CA 1.014377122 0.043581008 0.011293637 22.96869421 3.839948 2.023048 2.165421 8.361545 7.174648 5.446557 C1QTNF3 1.279008286 0.043453389 0.00420279 22.96116086 1.874444 2.023048 2.379345 6.544171 6.189775 7.020304 RIOK2 1.247866237 0.043453389 0.004672338 22.96116086 1.874444 2.023048 2.165421 6.544171 6.774676 5.882028 CETN3 1.19302659 0.043453389 0.005876148 22.96116086 1.874444 2.023048 2.165421 6.544171 7.406567 5.580533 C12orf35 1.179090721 0.043453389 0.00618918 22.96116086 3.350997 2.023048 2.379345 6.544171 7.31791 6.924055 MTERFD1 1.161402762 0.043453389 0.006570262 22.96116086 1.874444 2.023048 2.165421 6.544171 6.794431 5.446557 TMEM55A 0.950170014 0.043900827 0.01389248 22.96116086 1.874444 2.023048 2.165421 6.544171 7.292524 4.146207 YEATS4 0.75736983 0.046414887 0.025004423 22.96116086 1.874444 2.023048 2.165421 6.544171 6.774676 2.921909 LOC572558 1.353469445 0.043453389 0.003052739 22.95978186 1.874444 2.023048 2.165421 6.395481 6.613395 6.618407 LOC729987 1.252239637 0.043453389 0.004590677 22.95636454 4.263463 3.770995 4.285996 7.957464 9.435026 8.784285 OXNAD1 1.219809578 0.043453389 0.005196325 22.950162 2.201691 2.023048 2.379345 7.144104 5.920411 6.722123 FBXL13 1.25711159 0.043453389 0.004522627 22.80859486 6.186289 5.340619 5.225216 9.466036 10.697795 10.683012 ZMYM5 1.049337581 0.043568903 0.009949643 22.80173059 1.874444 2.023048 3.90836 6.651882 7.094585 6.385515 ATG3 1.145909948 0.043453389 0.006944539 22.78344152 1.874444 2.023048 2.995681 5.579836 7.505595 7.352555 ANKK1 1.105381766 0.04349335 0.008038108 22.73764785 6.008206 6.42919 5.609945 9.188227 10.558612 10.936201 MYSM1 1.254087593 0.043453389 0.004556652 22.69516974 2.201691 4.80797 4.285996 8.79031 9.25691 8.503924 HES1 1.151707567 0.043453389 0.006835658 22.64704292 6.898923 4.80797 5.225216 11.400174 10.701282 9.163078 H3F3C 1.11487893 0.043485739 0.007744811 22.61524911 7.546975 6.044198 6.800663 12.522423 11.299887 10.112044 ROR1 1.204467799 0.043453389 0.005509357 22.5945777 7.218633 6.502398 7.227914 10.67476 11.716537 11.789629 POLR2B 1.301024382 0.043453389 0.003923784 22.55572722 5.304463 4.830496 4.508334 9.799885 9.294336 9.276113 CHCHD5 1.285369228 0.043453389 0.00413474 22.55457658 4.263463 3.360637 3.324375 8.41912 7.819723 8.732403 ZNF117 1.057989887 0.043540291 0.009614154 22.52970593 3.350997 2.023048 4.754917 6.396698 8.402869 9.248674 ELF3 0.931051292 0.044025007 0.014771011 22.50469941 4.263463 6.849665 3.90836 11.341819 9.158864 7.553321 ZNF84 1.115063625 0.043485739 0.007738006 22.47087019 4.209882 4.389936 3.324375 7.210813 8.87992 8.732403 COL7A1 1.246126711 0.043453389 0.004726778 22.45491538 1.874444 3.360637 2.165421 6.339437 7.793829 7.849596 TECRL 1.131394847 0.043453389 0.007305206 22.41607031 4.309025 2.406905 2.165421 6.651882 8.332658 7.695565 FMO5 1.161055278 0.043453389 0.006597482 22.38212433 2.201691 3.872014 2.165421 7.477873 7.56803 6.649696 LOC100130093 1.083397887 0.043516135 0.008829534 22.36116014 2.201691 2.809601 4.449894 7.243046 7.292524 7.640338 PIM2 1.185715223 0.043453389 0.006046274 22.30822306 2.993831 3.360637 4.754917 9.137671 7.473335 8.564524 PPP1R3B 1.130144755 0.043453389 0.007346036 22.30822306 2.993831 4.413323 2.379345 8.447068 7.473335 7.218312 NDUFS4 0.948026902 0.043900827 0.013987751 22.29643679 4.209882 2.023048 2.165421 8.688623 7.406567 5.091834 APPL2 1.025993921 0.043577906 0.0107295 22.29283571 3.839948 4.351315 2.165421 6.283686 8.829823 8.32282 MYOM2 1.00784184 0.043581008 0.011525009 22.27963156 1.874444 2.023048 2.995681 7.167419 7.473335 4.790662 TCEAL8 1.330900548 0.043453389 0.003386186 22.24753286 1.874444 2.023048 2.165421 6.283686 6.640994 6.587378 CMBL 1.263152586 0.043453389 0.004406941 22.24753286 2.201691 2.023048 2.165421 8.087444 6.640994 6.129407 FKBP14 1.165173956 0.043453389 0.006509017 22.24753286 1.874444 2.809601 2.165421 7.33564 6.640994 5.900694 TTC13 1.304945821 0.043453389 0.003801293 22.24137525 1.874444 2.023048 2.165421 6.498222 6.189775 7.020304 CDKAL1 1.153339676 0.043453389 0.006774413 22.13476986 4.743564 3.872014 5.018694 8.65307 9.532215 8.340256 GORASP1 1.19006641 0.043453389 0.005978224 22.13126956 4.263463 3.770995 2.165421 8.239009 7.598264 8.287303 C2orf42 1.245053909 0.043453389 0.004747193 22.0856739 1.874444 2.406905 2.995681 7.394225 6.319269 7.46072 LOC441009 1.340949485 0.043453389 0.003222865 22.08498467 1.874444 2.023048 2.165421 6.339437 6.613395 6.587378 ARHGAP10 1.298241949 0.043453389 0.003964614 22.08498467 1.874444 2.023048 2.165421 6.339437 6.373501 7.695565 TRNAU1AP 1.030477019 0.043577906 0.010562096 22.08498467 1.874444 2.023048 3.764125 6.339437 6.551443 6.649696 FAM63B 1.10606033 0.04349335 0.008024498 22.08468177 3.819732 2.809601 4.754917 7.274575 8.469821 8.745549 SYNJ2BP 1.217673594 0.043453389 0.005257571 22.04628173 4.309025 3.360637 3.324375 7.394225 8.59507 8.771488 OSBPL8 1.0094965 0.043581008 0.011443348 22.03641419 5.316227 4.351315 4.449894 9.778045 8.97518 7.428484 SFT2D1 1.046800881 0.043577906 0.010038789 21.98250773 4.209882 2.809601 2.379345 7.792994 8.668166 6.051818 ABHD16A 1.128449419 0.043453389 0.007373256 21.91687869 1.874444 3.360637 2.379345 7.814607 7.31791 5.874974 PMPCA 1.090664614 0.043516135 0.008587275 21.91687869 5.056948 3.360637 2.379345 7.814607 7.440337 9.220702 RAB11FIP2 1.25564049 0.043453389 0.004543042 21.90773924 3.024504 2.023048 2.379345 7.477873 7.269549 6.455366 MRPL24 1.103071753 0.04349335 0.008106159 21.90645386 4.682076 3.32135 2.165421 8.033165 7.505595 7.774634 SCAMP1 1.107884556 0.043485739 0.007955767 21.8843391 1.874444 2.406905 3.935222 8.105092 7.187136 6.32627 TPD52 0.936912684 0.043994974 0.014494046 21.8843391 1.874444 3.770995 4.449894 9.847848 6.78473 6.32627 LYPLAL1 1.322376639 0.043453389 0.003535897 21.85954701 2.201691 2.406905 2.165421 6.651882 7.31791 6.587378 SH3KBP1 1.062286614 0.043540291 0.009484859 21.85212054 5.335413 3.32135 3.764125 7.771052 8.696398 8.374509 GBP6 1.073147113 0.043516135 0.009169786 21.82597742 2.201691 2.023048 2.165421 5.026959 6.613395 7.395512 IL17RB 0.852596969 0.044464174 0.018724736 21.82597742 1.874444 2.023048 2.165421 6.498222 6.613395 3.676349 CSRP2 0.912965448 0.044110923 0.015714188 21.80377418 2.993831 2.023048 2.165421 4.341916 7.440337 7.03218 GUCY1B3 1.04705003 0.043577906 0.010031984 21.7997463 3.839948 2.023048 2.165421 8.286188 7.406567 5.580533 FAM36A 1.183445161 0.043453389 0.006087104 21.78736275 4.743564 5.297868 4.508334 10.344114 9.188984 8.534542 PLAT 1.08313585 0.043516135 0.008849949 21.76011776 5.263699 3.770995 4.508834 10.671802 8.951948 7.611911 LOC100288198 1.276806347 0.043453389 0.004209595 21.74490341 1.874444 2.023048 2.165421 6.498222 6.608026 6.051818 MLPH 0.863856913 0.044377262 0.018178292 21.67698395 6.227577 3.770995 4.285996 10.780147 8.724089 6.73963 B3GALNT1 1.249034959 0.043453389 0.004651922 21.62717945 2.201691 2.406905 2.379345 6.814118 7.292524 6.195186 LIMA1 0.932357659 0.044025007 0.014709765 21.62717945 1.874444 5.487673 2.379345 6.814118 8.998044 6.73963 MAGI2-AS3 1.149391051 0.043453389 0.006876489 21.59666179 4.963444 4.389936 6.012527 8.822673 9.789758 9.910841 KIAA0907 1.143342564 0.043453389 0.007026199 21.59098171 1.874444 3.360637 2.379345 7.792994 7.56803 5.882028 LOC550643 1.048553766 0.043577906 0.009991153 21.59040227 4.263463 2.023048 2.165421 7.30543 7.292524 6.455366 DHFR 1.140539091 0.043453389 0.007141885 21.51224679 3.350997 4.389936 4.944468 7.856887 8.817023 9.123341 ZBED5 1.094317809 0.04349335 0.0084328 21.47217083 4.639409 2.406905 3.324375 7.748771 8.2398 7.291822 STS 1.220772879 0.043453389 0.005182715 21.43589975 1.874444 2.809601 2.165421 6.395481 6.78473 6.587378 TAF6 0.95119662 0.043900827 0.01385165 21.43589975 5.263699 2.809601 2.165421 7.835902 8.011679 6.587378 DNAJB4 1.10081803 0.04349335 0.008201429 21.41104943 3.839948 3.360637 5.217616 9.23707 9.637899 7.255535 NPHP3 1.200838175 0.043453389 0.005638653 21.41063031 2.993831 2.023048 2.165421 6.664985 7.414086 6.32627 PROS1 0.970877493 0.043709154 0.012956108 21.41063031 2.993831 2.406905 3.935222 5.579836 7.414086 8.650903 FBXL3 1.004374061 0.043588662 0.011687649 21.35817204 2.201691 2.406905 5.018694 7.477873 8.402869 6.618407 HIBADH 1.213528619 0.043453389 0.005339231 21.34509478 3.024504 3.32135 2.379345 8.014609 7.440337 6.722123 SCAPER 1.053208768 0.043568903 0.009820347 21.33405473 4.263463 2.023048 2.379345 7.814607 6.794431 6.722123 PVRL4 0.882367895 0.044229452 0.017338551 21.33405473 1.874444 4.413323 2.379345 8.885299 6.794431 5.091834 CSRNP2 1.128364492 0.043453389 0.007386866 21.27285194 3.839948 2.406905 4.508334 7.36523 8.453372 8.25089 BRP44 1.25909785 0.043453389 0.004468186 21.26659501 5.056948 4.80797 2.995681 9.252991 9.218487 9.051056 DPYD 1.076566114 0.043516135 0.009060905 21.24781347 1.874444 2.023048 4.449894 6.283686 8.486085 7.395512 ZNF26 1.179547641 0.043453389 0.00617557 21.23998086 2.993831 2.809601 2.165421 6.283686 7.414086 7.21312 SLC24A4 1.255898831 0.043453389 0.004536237 21.17714343 2.993831 2.406905 2.165421 6.811341 6.78473 7.180104 KCTD3 1.022241988 0.043577906 0.010947261 21.15034203 2.201691 3.770995 2.165421 8.173604 7.107836 5.580533 MFAP1 1.017234996 0.043581008 0.011157537 21.13798314 2.201691 2.023048 3.324375 7.726141 7.406567 5.091834 LOC100506710 1.03147008 0.043577906 0.010528071 21.10965547 5.304463 3.360637 2.995681 8.79031 8.011679 7.395512 CNNM2 1.182598819 0.043453389 0.00610752 21.07156548 7.198002 7.197097 7.107458 10.752415 11.594323 11.64277 KRT8 1.029676591 0.043577906 0.010568901 21.02626007 3.350997 5.809601 3.324375 10.203722 8.402869 7.428484 RAB42 1.19698114 0.043453389 0.005767268 21.02202167 4.963444 6.466258 6.056062 9.847848 10.589051 10.449891 GBA2 1.162542767 0.043453389 0.006556652 20.96022135 3.024504 3.872014 2.165421 8.014609 7.414086 6.931222 AKAP7 1.061857776 0.043540291 0.009491664 20.93037391 1.874444 2.406905 2.165421 6.651882 6.794431 5.091834 ABHD14A 1.28832932 0.043453389 0.004100715 20.90856097 2.201691 2.023048 2.165421 6.252746 6.551443 7.352555 CXorf26 0.977493102 0.043661316 0.012646478 20.90856097 1.874444 2.023048 2.165421 6.544171 6.551443 4.476242 LEO1 0.75724389 0.046424242 0.025024158 20.90856097 1.874444 2.809601 2.165421 8.447068 6.551443 2.921909 CKLF 1.081303605 0.043516135 0.008904389 20.90371112 2.201691 2.023048 3.90836 7.877571 6.551443 6.587378 IPO11 1.119005761 0.043485739 0.007615515 20.89764534 2.201691 2.023048 2.165421 6.660689 6.363925 3.961222 TADA3 1.101278571 0.04349335 0.008174209 20.89764534 3.839948 3.872014 2.165421 6.550689 7.989035 9.008063 APTX 1.24183747 0.043453389 0.004788023 20.88707221 2.201691 2.023048 2.165421 7.976765 6.549959 6.051818 RNLS 1.13918867 0.043453389 0.007182715 20.88707221 2.201691 2.023048 2.165421 7.856887 6.549959 5.426231 SVIP 1.121333981 0.043480953 0.007569241 20.88707221 3.024504 2.023048 2.165421 8.974419 6.549959 5.882028 ASH2L 1.09321024 0.04349335 0.008480436 20.88707221 2.201691 2.023048 2.165421 5.252045 6.549959 6.69026 NSMCE4A 1.127984451 0.043453389 0.007393671 20.80344652 1.874444 3.32135 2.165421 6.544171 7.107836 6.32627 CXorf23 1.007593043 0.043581008 0.011538619 20.80344652 2.201691 2.023048 2.165421 6.544171 6.640994 4.790662 LRIG3 0.963881502 0.043778104 0.013214699 20.80344652 1.874444 2.406905 2.165421 6.544171 7.138979 4.476242 IDH2 1.072214024 0.043516135 0.009197006 20.79785347 2.201691 4.750708 2.165421 9.12907 7.740604 6.385515 ANKS1B 1.012247532 0.043581008 0.011375298 20.77592572 5.316227 3.872014 4.944468 9.693068 9.409671 7.395512 RAB1A 1.054081527 0.043568903 0.009799932 20.7661745 6.186289 6.049721 6.282905 10.852466 10.562453 9.072081 CTBS 1.016957613 0.043581008 0.011171147 20.73033449 5.056948 3.32135 5.018694 8.156778 7.91889 9.430619 RP9P 1.019143444 0.043577906 0.011090167 20.73002377 1.874444 2.023048 3.935222 6.396698 7.174648 6.32627 GATA3 1.115838352 0.043485739 0.007710786 20.729099 3.839948 5.362142 4.724406 10.302647 8.777924 8.213534 SIRT5 1.284826826 0.043453389 0.004141545 20.71254249 1.874444 2.023048 2.165421 6.395481 6.613395 6.129407 P4HA2 1.148177474 0.043453389 0.006910514 20.71254249 1.874444 2.023048 2.165421 6.395481 6.78473 5.426231 LPHN3 1.139875825 0.043453389 0.00717591 20.71254249 1.874444 2.023048 2.165421 6.395481 5.353925 7.291822 DNM1P35 1.132212428 0.043453389 0.007284791 20.71254249 3.350997 2.023048 2.165421 6.395481 6.640994 7.033813 LRTM2 1.096873569 0.04349335 0.008330725 20.71254249 1.874444 2.023048 2.165421 6.395481 7.292524 5.106393 RARB 1.080631367 0.043516135 0.008945219 20.68485257 3.839948 2.809601 2.165421 6.244586 8.518072 7.180104 TMEM237 1.199436956 0.043453389 0.005706703 20.67969012 1.874444 2.809601 2.165421 6.244586 7.269549 6.455366 KIT 1.022370647 0.043577906 0.010940456 20.67927292 4.209882 4.351315 3.324375 10.321643 8.579995 6.455366 NFYC 1.195031766 0.043453389 0.005814903 20.67692246 3.024504 2.406905 3.935222 7.30543 7.31791 8.305171 ZNF622 1.110659104 0.043485739 0.007894522 20.66820086 4.209882 2.406905 3.764125 8.579223 7.870158 7.03218 SRA1 0.985128705 0.043626235 0.012361347 20.66820086 4.209882 2.023048 2.165421 8.579223 6.640994 5.882028 ATF6 1.000114757 0.043588662 0.011844165 20.62567356 5.779429 4.736586 2.379345 9.102956 9.1177 7.695565 MMAB 1.027196216 0.043577906 0.010681865 20.59504363 6.898923 4.389936 6.282905 9.252991 9.956624 11.263149 EPCAM 0.956974648 0.043835088 0.013576046 20.59168372 3.819732 3.32135 2.165421 10.492308 7.68534 5.091834 ACYP2 1.092819971 0.04349335 0.008494046 20.57773238 1.874444 2.406905 3.764125 7.877571 6.237456 6.931222 NREP 1.188300114 0.043453389 0.006005444 20.56996084 3.839948 2.023048 2.165421 7.856887 8.140553 6.385515 TF 1.131628078 0.043453389 0.007298401 20.56996084 1.874444 2.023048 2.165421 7.631894 5.306419 6.385515 CCDC23 1.060574149 0.043540291 0.009525689 20.56996084 4.209882 2.023048 2.165421 7.167419 7.656894 6.385515 MOV10 0.987570112 0.043626235 0.012272882 20.53887792 2.201691 2.406905 2.379345 4.802615 7.191402 6.73963 RFC2 1.182203662 0.043453389 0.006127935 20.50377435 1.874444 2.809601 3.324375 7.167419 6.640994 7.327219 IL23R 0.97524481 0.043661316 0.012734944 20.50377435 5.335413 2.809601 5.596986 7.167419 9.563208 10.214881 MRPL3 1.149278427 0.043453389 0.006883294 20.43692117 4.743564 4.389936 2.379345 8.286188 9.09667 8.03232 SUMF1 1.169405213 0.043453389 0.006440966 20.4297469 1.874444 3.360637 2.165421 7.037879 7.713236 6.195186 MIR4454 1.197697024 0.043453389 0.005747533 20.3993743 1.874444 2.023048 2.165421 5.705318 6.373501 6.587378 FANCM 1.155983156 0.043453389 0.006719973 20.3993743 1.874444 2.023048 2.995681 6.664985 6.373501 6.32627 RPA3 1.149575588 0.043453389 0.006869684 20.3993743 1.874444 2.023048 2.165421 7.877571 6.373501 5.426231 OPRM1 1.069158738 0.043516135 0.009299081 20.3993743 1.874444 2.023048 2.165421 5.026959 6.373501 6.649696 IQCF3 0.960220128 0.043802358 0.013379381 20.3993743 1.874444 2.023048 2.165421 4.341916 6.373501 6.924055 PIGX 1.229453629 0.043453389 0.004985369 20.38946458 2.201691 2.406905 2.165421 7.33564 6.551443 6.129407 MYO6 1.015479636 0.043581008 0.011218782 20.38631556 4.682076 5.661685 3.324375 10.011214 8.119857 8.175185 TFCP2L1 1.219575506 0.043453389 0.00521674 20.37881995 2.201691 2.406905 3.324375 6.550689 7.292524 7.611911 OLFML2A 0.822433615 0.045030324 0.020587955 20.37881995 2.201691 3.770995 5.544653 6.550689 9.99691 6.618407 MYD88 1.219677889 0.043453389 0.00520313 20.36850932 2.201691 2.023048 2.379345 8.069577 6.549959 6.051818 DPH3 1.093824775 0.04349335 0.008453215 20.35577471 4.815804 3.770995 2.995681 9.16317 8.200916 7.291822 GEM 0.99698263 0.043626235 0.011938074 20.3529917 5.304463 6.139057 7.809663 9.651632 10.905551 10.880675 SCUBE2 0.939618499 0.043955231 0.014392651 20.34870405 1.874444 3.32135 6.355801 9.388882 7.656894 7.668215 C1QTNF2 0.71652796 0.047853797 0.028232732 20.29114353 1.874444 2.023048 2.379345 2.820813 6.373501 6.722123 PLCG2 1.049089858 0.043568903 0.009956448 20.2869598 2.201691 2.406905 2.165421 6.544171 5.165949 6.924055 HTR2A 1.167811651 0.043453389 0.006468186 20.20079154 6.417969 5.340619 6.054038 10.174762 11.162428 9.676959 SACM1L 1.040558281 0.043577906 0.0102967 20.18965012 2.201691 3.32135 4.285996 7.835902 7.656894 6.618407 IL33 1.023219628 0.043577906 0.010906431 20.18965012 4.309025 3.32135 2.165421 6.244586 7.656894 8.705744 ENY2 1.079167605 0.043516135 0.008992855 20.13543034 4.682076 2.023048 3.324375 7.656039 7.76462 7.553321 TMEM14A 1.194985779 0.043453389 0.005821708 20.1336666 1.874444 3.770995 2.995681 7.274575 7.627877 7.327219 CRTAM 1.108430436 0.043485739 0.007948962 20.12089333 1.874444 3.32135 4.285996 8.616619 7.191402 7.218312 C15orf34 1.172909757 0.043453389 0.006325281 20.12013724 4.209882 5.148082 5.702912 9.058353 9.500541 9.478651 ANXA1 1.097821099 0.04349335 0.008276284 20.06641628 6.099991 8.819674 7.462086 12.826968 11.788797 11.358224 METTL10 1.086679873 0.043516135 0.008723375 20.02983597 2.993831 2.023048 3.324375 8.301578 7.31791 5.874974 SERPINA1 0.888229908 0.044203301 0.017114665 20.02863005 3.839948 4.911517 4.285996 11.771561 8.609988 5.874974 GNG5 1.057261832 0.043540291 0.009668595 19.99626604 5.982974 4.830496 5.544653 10.834062 9.866312 8.391335 RFXAP 1.288768809 0.043453389 0.004080299 19.9835652 1.874444 2.023048 2.165421 6.544171 6.319269 6.195186 GGH 1.263037625 0.043453389 0.004413746 19.9835652 1.874444 2.023048 2.165421 7.42265 6.237456 6.195186 PYROXD2 1.240993728 0.043453389 0.004808438 19.9835652 1.874444 2.023048 2.379345 6.283686 7.598264 6.195186 KIAA0528 1.231548362 0.043453389 0.004951344 19.9835652 1.874444 2.406905 2.165421 6.339437 7.68534 6.195486 HSPE1 0.956380122 0.043840967 0.013607349 19.98349795 6.678389 7.939256 7.575421 12.581933 11.896158 9.697401 SMC5 1.190954715 0.043453389 0.005964614 19.96893779 4.639409 3.770995 3.935222 8.254907 8.65384 8.095288 SNRPG 0.83044419 0.044867325 0.020059884 19.93289759 5.056948 4.736586 4.449894 10.191381 9.053666 6.106561 PTER 1.171711187 0.043453389 0.006372916 19.92336801 1.874444 2.023048 2.165421 6.339437 6.640994 5.580533 RNASE6 0.980367976 0.043626235 0.012558693 19.92336801 1.874444 2.023048 3.90836 6.339437 6.205902 6.73963 C9orf3 0.921826003 0.044110923 0.015268459 19.91756292 4.309025 5.297868 4.285996 6.814118 8.892178 9.613837 LYRM7 1.050342722 0.043568903 0.009922423 19.91753306 4.682076 2.809601 5.018694 7.33564 8.998044 9.211256 GPX7 1.082214597 0.043516135 0.008870364 19.90719656 4.309025 2.406905 2.995681 7.835902 7.819723 6.722123 CD46 1.153439298 0.043453389 0.006760803 19.88226484 6.186289 3.03611 4.944468 10.862879 10.343377 9.257878 ANKRD26 1.097397861 0.04349335 0.008303505 19.84790949 3.350997 2.023048 2.379345 7.726141 6.043524 6.69026 ESYT2 1.200309661 0.043453389 0.005686288 19.79837935 3.350997 3.770995 4.449894 8.757204 8.624754 7.582913 LINC00221 0.98072241 0.043626235 0.012545083 19.78762072 1.874444 3.32135 2.165421 4.802615 7.627877 7.395512 LOC100507600 1.266177522 0.043453389 0.004352501 19.74236107 1.874444 2.023048 2.165421 6.067497 6.08026 6.32627 GIMAP4 1.231743293 0.043453389 0.004944539 19.74236107 1.874444 2.023048 2.165421 5.891233 6.608026 6.32627 CAP2 1.212193906 0.043453389 0.005373256 19.74236107 1.874444 2.023048 2.165421 8.566539 5.920411 6.32627 ATP6AP2 1.011380456 0.043581008 0.011402518 19.74236107 4.682076 2.023048 3.76125 9.60897 8.055928 6.323627 N4BP2L1 1.112490718 0.043485739 0.007826472 19.73651413 3.819732 3.32135 2.165421 8.122528 7.094585 6.924055 RASA1 1.028919422 0.043577906 0.010613814 19.72002953 5.328526 3.872014 2.995681 8.173604 8.277663 7.849596 SULT1A1 1.136237798 0.043453389 0.007223545 19.69770527 3.839948 2.809601 3.935222 7.109557 7.767462 8.758577 TRERF1 1.00488519 0.043588662 0.011660429 19.69770527 2.993831 2.809601 4.724406 7.109557 7.713236 7.352555 LAMTOR1 1.072966029 0.043516135 0.009176591 19.69268718 5.856559 4.351315 2.379345 8.616619 8.97518 8.650903 COPB2 0.971682926 0.043681142 0.012920041 19.65890821 6.306772 4.830496 3.935222 9.322536 9.179013 8.232333 KIAA0564 1.262501049 0.043453389 0.004427356 19.6467864 1.874444 2.023048 2.165421 7.504712 6.319269 6.129407 CD247 1.200428549 0.043453389 0.005679483 19.6467864 1.874444 2.023048 2.165421 5.728038 6.319269 6.931222 ZNF138 1.182505218 0.043453389 0.006114325 19.6467864 1.874444 2.023048 2.165421 5.728038 6.319269 6.931222 HPRT1 1.144861288 0.043453389 0.006985369 19.6467864 1.874444 2.023048 2.165421 7.748771 6.319269 5.426231 SNORA78 1.141656924 0.043453389 0.00706703 19.6467864 1.874444 2.023048 2.995681 6.063041 6.319269 7.553321 SNTB1 1.09377877 0.04349335 0.00846002 19.6467864 1.874444 2.023048 2.165421 8.361545 6.319269 5.106393 ABCA13 0.840786271 0.044709815 0.019450834 19.6467864 1.874444 2.023048 2.165421 6.544171 6.319269 3.676349 LOC646214 1.134958042 0.043453389 0.007237155 19.60392616 8.55164 8.491292 8.693844 11.982016 13.005848 12.844711 FAM102B 0.78253485 0.045701235 0.023138482 19.5660358 4.263463 2.023048 3.324375 8.553743 8.119857 4.146207 ITIH4 1.236080159 0.043453389 0.004869684 19.56150134 1.874444 2.023048 2.165421 6.339437 5.920411 6.455366 TDP1 1.211473047 0.043453389 0.005407281 19.56150134 2.201691 2.023048 2.165421 5.891233 7.473335 6.455366 PIGM 1.169458941 0.043453389 0.006427356 19.56150134 2.201691 3.360637 2.165421 6.811341 7.627877 6.453666 ATG5 0.912189522 0.044142622 0.015754338 19.56150134 5.056948 2.406905 2.165421 7.177844 7.505595 6.455366 LOC100500773 1.234168281 0.043453389 0.004924124 19.54991374 8.051258 7.458616 7.913913 12.203003 12.218027 11.795962 KIAA0040 1.154245989 0.043453389 0.006747193 19.5210601 2.993831 4.413323 5.225216 8.700282 8.469821 8.952456 IFT172 1.004842476 0.043588662 0.011667234 19.50792269 2.201691 3.32135 5.217616 7.607339 7.269549 8.456743 SLC19A3 1.066391205 0.043516135 0.009367132 19.49434474 1.874444 2.809601 3.90836 6.283686 7.094585 8.010706 FLJ30838 0.99232907 0.043626235 0.012116366 19.49434474 2.993831 2.809601 2.165421 5.252045 7.094585 7.327219 C14orf101 1.083321605 0.043516135 0.008843144 19.38559577 4.309025 3.32135 2.165421 6.814118 7.598261 8.357484 MMRN2 1.221133942 0.043453389 0.00517591 19.34471928 5.056948 4.750708 5.571599 9.196483 9.330816 9.750536 PSMB1 1.170873288 0.043453389 0.006406941 19.33721294 6.648293 4.911517 5.723602 9.978073 9.99691 10.520428 LRIF1 1.249543553 0.043453389 0.004645117 19.29761994 1.874444 2.023048 2.379345 6.063041 6.549959 6.649696 BIVM 1.141320636 0.043453389 0.00708064 19.29761994 2.993831 2.023048 2.379345 6.067497 7.269549 6.649696 LRP11 0.848463728 0.044592081 0.019004423 19.24056029 2.993831 3.32135 2.165421 7.25991 7.656894 4.476242 LMO7 0.872670666 0.044299467 0.017744811 19.22033256 1.874444 2.809601 2.165421 7.074163 6.551443 4.146207 LOC283585 1.096332721 0.04349335 0.00835114 19.21590049 1.874444 2.023048 2.995681 7.25991 6.551443 5.634184 MINOS1 1.150081551 0.043453389 0.006856073 19.20986307 5.056948 3.872014 4.449894 9.98762 8.63937 8.135789 OAF 0.870981499 0.044325295 0.017831916 19.20160099 4.309025 5.297868 4.508334 6.544171 9.985514 8.771488 NCBP2 1.030836164 0.043577906 0.010541681 19.19034259 4.639409 4.830496 2.379345 7.36523 8.258856 9.092804 HOXD8 1.057943224 0.043540291 0.009627765 19.18157667 1.874444 2.023048 2.379345 5.026959 6.640994 6.618407 UQCRC2 1.217839329 0.043453389 0.005250766 19.17901973 5.335413 4.736586 4.508334 9.45919 8.998044 8.986077 PTPN21 1.191306876 0.043453389 0.005937394 19.17585071 2.993831 2.023048 2.165421 6.814118 7.25505 6.195186 IPO8 1.2595572 0.043453389 0.004461381 19.16813679 1.874444 2.023048 2.165421 6.283686 7.414086 6.129407 KIAA1009 1.082366215 0.043516135 0.008863559 19.16813679 2.993831 2.023048 4.449894 6.283686 8.486085 8.488368 SNRPF 1.123147798 0.043453389 0.007495747 19.15771161 3.839948 4.389936 2.995681 8.460842 8.2398 7.255535 HSF2 1.097998315 0.04349335 0.008249064 19.15127384 3.024504 2.023048 2.995681 7.556937 7.25505 5.882028 LIN28A 0.910420501 0.044159136 0.01589248 19.15127384 4.815804 2.023048 2.995681 6.339437 7.25505 7.492252 WDR33 1.227821619 0.043453389 0.005026199 19.14204453 4.743564 4.351315 4.944468 9.452312 8.609988 8.974957 MAGI1 1.055590879 0.043540291 0.009750255 19.09786014 3.839948 3.770995 2.379345 6.857154 7.174648 8.095288 ZNF184 1.26741054 0.043453389 0.004332086 19.09289409 1.874444 2.023048 2.165421 6.498222 6.237456 6.129407 UNC13B 1.113073689 0.043485739 0.007812862 19.09289409 1.874444 3.32135 2.165421 6.664985 7.094585 6.129407 SRPK2 0.953574578 0.043857532 0.013735965 19.09289409 1.874444 4.736586 2.379345 7.33564 7.598264 6.129407 CCNI 1.175410757 0.043453389 0.006277645 19.07312948 7.259029 5.148082 6.489771 11.099197 10.666023 10.74324 DNAJC24 1.170835072 0.043453389 0.006413746 19.03370769 4.309025 2.809601 3.764125 8.014609 8.220489 7.640338 LOC100131564 1.119389173 0.043485739 0.00760871 19.0053109 4.209882 6.060401 5.018694 9.058353 9.722706 9.267025 PARK7 1.064398047 0.043516135 0.009407962 18.96510715 4.963444 4.389936 2.379345 7.976765 9.20872 7.748756 TNFRSF10D 1.140156922 0.043453389 0.0071623 18.96118638 3.350997 2.406905 2.995681 6.651882 6.861783 8.678584 PM20D2 1.083395294 0.043516135 0.008836339 18.88360241 1.874444 3.872014 2.379345 7.814607 6.549959 6.618407 ADAM22 0.929254982 0.044037172 0.014854712 18.81862481 1.874444 2.406905 4.449894 7.243046 6.640994 6.195186 OR2H1 1.192612573 0.043453389 0.005889758 18.81811624 1.874444 2.406905 2.379345 5.891233 6.613395 7.180104 ANAPC4 1.256476775 0.043453389 0.004529432 18.792918 1.874444 2.023048 2.165421 6.252746 7.174648 6.106561 PGCP 1.097967478 0.04349335 0.008255869 18.792918 1.874444 2.023048 3.324375 6.252746 8.098861 6.106561 SLC25A27 1.044256776 0.043577906 0.010194624 18.792918 1.874444 2.406905 3.90836 7.33564 7.107836 6.106561 FUT8 1.156828145 0.043453389 0.006699558 18.78197464 2.201691 2.023048 2.165421 6.396698 8.077554 5.634184 PMVK 1.224828626 0.043453389 0.00509425 18.76613612 1.874444 2.406905 2.165421 6.395481 6.549959 6.106561 MRPL21 1.164105335 0.043453389 0.006515822 18.76613612 2.993831 2.023048 2.165421 6.395481 7.107836 6.32627 AGMO 1.104090868 0.04349335 0.008078938 18.76613612 3.350997 2.023048 2.165421 6.395481 6.373501 7.033813 PFDN1 0.912789636 0.044110923 0.015720994 18.76143219 1.874444 2.023048 2.165421 6.252746 6.640994 4.146207 TRIAP1 0.981542702 0.043626235 0.012524668 18.74296867 1.874444 2.809601 2.995681 7.037879 7.406567 5.091834 RDH11 0.8192624 0.045111103 0.020777816 18.70995721 6.973646 4.351315 3.935222 8.811966 8.160956 8.60836 RGL1 1.145033141 0.043453389 0.006971759 18.70713686 4.309025 3.770995 2.995681 7.177844 8.453372 8.534542 VAMP8 1.048849678 0.043577906 0.009970738 18.692517 5.056948 5.340619 2.165421 9.565008 8.2398 8.374509 SRP19 1.058655016 0.043540291 0.009573324 18.69022689 3.350997 2.809601 4.285996 9.410337 7.094585 7.033813 GIT2 1.024567702 0.043577906 0.010831575 18.69022689 1.874444 2.809601 3.90836 6.252746 7.269549 7.033813 PPP1CC 1.161138791 0.043453389 0.006583872 18.67413032 5.056948 6.072636 5.609945 9.410337 9.897049 9.832914 EBPL 1.234283596 0.043453389 0.004917319 18.65561977 1.874444 2.023048 2.165421 6.244586 7.819723 6.051818 PRPF18 1.225478172 0.043453389 0.00506703 18.65561977 1.874444 2.023048 2.165421 6.244586 6.794431 5.900694 PCA3 1.219247194 0.043453389 0.005223545 18.65561977 1.874444 2.023048 2.165421 6.244586 5.936219 7.668215 LOC283856 0.976568056 0.043661316 0.012660088 18.61044216 2.993831 3.770995 5.544653 7.42265 7.989035 8.906373 BAG3 1.120467153 0.043485739 0.00758149 18.60437624 5.744513 6.931478 7.663508 10.780147 11.194951 11.149048 FLJ41200 1.203136819 0.043453389 0.005536577 18.59745833 3.350997 2.406905 3.764125 7.274575 7.56803 7.943848 THNSL2 0.8622511 0.044379352 0.018285812 18.59745833 3.350997 2.809601 2.165421 7.36523 7.56803 4.476242 C10orf32 1.045039813 0.043577906 0.010167404 18.57287155 4.963444 2.406905 4.449894 8.665019 8.668166 7.395512 KLRB1 1.221913282 0.043453389 0.0051623 18.56364137 1.874444 2.023048 2.165421 6.651882 6.237456 5.882028 SCG3 1.191887689 0.043453389 0.005923784 18.56364137 1.874444 2.023048 2.165421 5.728038 6.237456 7.020304 C7orf44 1.162911025 0.043453389 0.006543042 18.56364137 1.874444 2.023048 2.165421 6.544171 6.237456 5.580533 CD8B 1.080789907 0.043516135 0.008924804 18.56364137 1.874444 2.023048 2.165421 7.177844 6.237456 5.091834 TNFSF15 1.043879803 0.043577906 0.010208234 18.56364137 1.874444 2.023048 2.165421 4.894482 6.237456 6.942983 ABCB5 1.006664853 0.043588662 0.011605988 18.56364137 1.874444 2.023048 2.165421 4.718672 6.237456 6.649696 RPP38 1.004825809 0.043588662 0.011680844 18.56364137 1.874444 2.023048 2.165421 7.995811 6.237456 4.562324 GGTA1P 0.902660572 0.044190907 0.016303505 18.56364137 1.874444 2.023048 2.379345 6.954147 6.237456 4.146207 TMEM72-AS1 0.902327077 0.044190907 0.01633753 18.56364137 1.874444 2.023048 2.165421 6.395481 6.237456 4.146207 MNS1 0.828487216 0.044930476 0.020236815 18.56364137 1.874444 2.023048 2.379345 6.814118 6.237456 3.676349 ZBTB11 0.849521549 0.044521554 0.018911194 18.5605534 1.874444 2.023048 3.90836 8.122528 7.269549 4.146207 KCTD10 1.097778152 0.04349335 0.008283089 18.52674722 3.839948 3.770995 2.379345 8.051486 7.406567 7.020304 FOXP2 1.119992628 0.043485739 0.0075951 18.52628879 1.874444 2.406905 3.324375 6.339437 7.107836 6.618407 AMPD2 1.070724754 0.043516135 0.009231031 18.51071886 4.309025 2.406905 4.285996 7.918071 7.269549 8.519314 GAR1 1.11204971 0.043485739 0.007840082 18.5032964 1.874444 3.32135 2.165421 7.531061 6.861783 5.900694 FLJ25363 1.093505943 0.04349335 0.008466825 18.49025955 4.815804 4.351315 4.754917 7.771052 8.963611 9.613837 PTPN4 1.205839119 0.043453389 0.005488942 18.48239708 2.201691 2.023048 2.165421 6.960054 6.373501 5.882028 ACN9 1.095626718 0.04349335 0.008371555 18.48239708 3.024504 2.023048 2.165421 7.25991 6.373501 5.874974 ARL6IP6 0.957485579 0.043835088 0.013548826 18.48239708 1.874444 2.406905 2.165421 6.814118 6.373501 4.562324 FAF1 1.070471075 0.043516135 0.009237836 18.48179558 4.209882 2.406905 2.379345 7.144104 7.96603 6.587378 RAPGEF6 1.121615148 0.043480953 0.007555631 18.47360161 4.309025 3.360637 3.324375 7.556937 7.56803 7.873743 OXTR 1.000590668 0.043588662 0.011830555 18.47360161 2.201691 3.360637 2.165421 5.448591 7.56803 6.587378 SMAD5 1.225623816 0.043453389 0.005060225 18.47267198 4.309025 4.413323 3.90836 8.604261 8.609988 8.11568 RRAS2 1.008119222 0.043581008 0.011511398 18.44988872 2.201691 3.872014 4.508334 8.993498 8.077554 6.385515 ZG16 1.114684319 0.043485739 0.007758421 18.42712866 6.58615 6.228068 7.250844 10.153715 11.454603 10.862687 LOC100130451 0.926075252 0.04406867 0.0150541 18.31603729 1.874444 3.770995 3.935222 5.448591 7.96603 8.194487 IGSF9B 0.948769591 0.043900827 0.013940116 18.31430117 4.309025 4.351315 2.995681 6.252746 8.624754 8.503924 PLSCR4 0.836290021 0.044768725 0.019682205 18.28225372 3.839948 3.32135 4.508334 5.252045 10.142544 8.03232 C10orf116 1.100867431 0.04349335 0.008194624 18.27011835 6.008206 7.197097 6.919905 10.19962 10.690795 12.407415 LOC254128 0.852905659 0.044464174 0.018704321 18.24559808 3.024504 3.360637 4.449894 5.252045 8.63937 8.11568 GVINP1 1.121677954 0.043480953 0.007548826 18.23632159 4.682076 4.389936 5.217616 9.590293 8.2398 8.870819 BCDIN3D 1.128446657 0.043453389 0.007380061 18.2344872 1.874444 2.023048 2.995681 6.063041 6.189775 8.213534 STXBP5 1.124573853 0.043453389 0.007461722 18.2344872 1.874444 2.406905 2.995681 6.063041 7.292524 6.455366 LOC100506085 1.178089764 0.043453389 0.006223205 18.21816902 4.743564 4.413323 3.935222 8.122528 8.59507 9.02972 ZDHHC23 1.216336801 0.043453389 0.005284791 18.16203854 1.874444 2.023048 2.165421 6.814118 6.205902 5.874974 MST1P2 1.192595927 0.043453389 0.005896563 18.16203854 1.874444 2.023048 2.165421 5.743334 6.205902 6.649696 FLJ44635 1.168690434 0.043453389 0.006461381 18.16203854 2.993831 2.023048 2.165421 6.954147 6.205902 6.649696 C9orf82 1.146649422 0.043453389 0.006930929 18.16203854 1.874444 2.023048 2.379345 7.177844 6.205902 5.634184 NCAPG2 1.136541966 0.043453389 0.007209935 18.16203854 1.874444 2.023048 2.165421 6.664985 6.205902 5.446557 CES4A 1.127486816 0.043453389 0.007400476 18.16203854 1.874444 2.023048 2.165421 6.395481 6.205902 5.426231 MED21 1.080989067 0.043516135 0.008917999 18.16203854 1.874444 2.023048 2.165421 7.792994 6.205902 5.091834 VRK1 1.079327258 0.043516135 0.00898605 18.16203854 1.874444 2.023048 2.165421 7.33564 6.205902 5.091834 C4orf34 0.972469599 0.043681142 0.012879211 18.16203854 1.874444 2.023048 2.165421 6.960054 6.205902 4.476242 ACSL5 0.881982872 0.044229452 0.017352161 18.16203854 4.743564 2.023048 2.165421 6.960054 6.205902 6.722123 POC1B 0.864316456 0.044377262 0.018137462 18.16203854 1.874444 2.023048 2.165421 7.42265 6.205902 3.676349 LOC100216479 0.848590249 0.044592081 0.018984008 18.16203854 1.874444 2.023048 2.165421 7.109557 6.205902 3.630092 TMEM45A 0.755093585 0.046508764 0.025261654 18.16203854 1.874444 2.023048 2.165421 7.167419 6.205902 2.921909 GLMN 0.741421875 0.046993264 0.026259952 18.16203854 1.874444 2.023048 2.165421 6.811341 6.205902 2.921909 KDM4C 1.117443201 0.043485739 0.007649541 18.13640401 2.993831 2.406905 2.379345 7.109557 7.174648 5.882028 ZNF438 1.244865244 0.043453389 0.004760803 18.09318541 1.874444 2.023048 2.165421 6.183122 6.774676 6.051818 ECHS1 1.062558941 0.043516135 0.009462402 18.08208224 4.263463 4.351315 2.165421 8.527804 7.713236 7.36177 FTSJ2 0.81921377 0.045111103 0.020784621 18.05112222 1.874444 2.023048 2.165421 6.339437 6.205902 3.630092 SPP1 0.749329358 0.046728791 0.025692412 18.05112222 1.874444 3.770995 2.165421 6.339437 8.402869 3.676349 PNRC1 1.216199662 0.043453389 0.005291596 18.03795748 8.161926 6.139057 8.037751 12.00996 12.33489 12.198613 PPP1R2P9 1.201419866 0.043453389 0.005597822 18.02762962 1.874444 2.023048 2.165421 8.239009 5.920411 6.195186 GALT 1.116380998 0.043485739 0.007697176 18.02762962 1.874444 2.023048 2.165421 5.320955 7.25505 6.195186 ZBTB24 1.091583046 0.0435113 0.008559374 18.02762962 3.350997 2.023048 2.165421 6.811341 6.608026 6.195186 MFSD4 1.081306041 0.043516135 0.008897584 18.02762962 1.874444 2.023048 2.165421 6.550689 5.165949 6.195186 POLK 1.009916836 0.043581008 0.011436543 18.02762962 3.024504 2.023048 3.935222 7.30543 7.269549 6.195186 NDUFS1 0.998047964 0.043626235 0.011917659 18.02762962 4.209882 2.023048 2.165421 7.835902 6.613395 6.195186 ITGA4 0.946653766 0.043900827 0.014069411 18.02712992 1.874444 2.023048 2.379345 6.339437 6.551443 4.476242 SLC16A2 1.088035473 0.043516135 0.008682545 18.023535 2.201691 3.360637 2.165421 6.339437 6.373501 7.03218 SMEK1 1.131643294 0.043453389 0.007291596 18.02163406 4.263463 3.770995 2.995681 8.222933 7.942653 7.352555 LOC653566 1.235259126 0.043453389 0.004896904 17.99088536 3.819732 2.023048 3.90836 7.976765 8.077554 7.943848 MT1F 1.228662523 0.043453389 0.004998979 17.98946004 1.874444 2.023048 2.165421 7.210813 6.043524 6.129407 LTB 1.228599552 0.043453389 0.005005784 17.98946004 1.874444 2.023048 2.165421 6.063041 6.043524 6.618407 COG5 0.955579004 0.043840967 0.01366179 17.98946004 1.874444 3.872014 3.764125 8.665019 6.043524 6.942983 ANXA3 1.167640125 0.043453389 0.006474991 17.96015231 1.874444 2.023048 2.165421 5.743334 6.189775 8.84662 IL20RA 1.157010759 0.043453389 0.006685948 17.96015231 1.874444 2.023048 2.165421 7.631894 6.189775 5.580533 MTCP1NB 1.133343532 0.043453389 0.007264376 17.96015231 1.874444 2.023048 2.165421 7.394225 6.189775 5.426231 CYP7B1 1.006149944 0.043588662 0.011612793 17.96015231 1.874444 2.023048 2.165421 4.718672 6.189775 6.73963 UCP2 0.969580348 0.043726704 0.013009867 17.96015231 4.263463 2.023048 2.165421 6.960054 6.189775 6.924055 ANAPC10 0.881413949 0.044251488 0.017374617 17.96015231 1.874444 2.023048 2.165421 8.527804 6.189775 3.630092 GTF2H2D 0.852207565 0.044480228 0.018753317 17.96015231 1.874444 2.023048 2.165421 7.25991 6.189775 3.630092 KIAA1143 1.14499078 0.043453389 0.006978564 17.91806264 4.639409 4.351315 2.379345 8.514658 8.737737 7.825039 TMCO1 1.01542368 0.043581008 0.011225587 17.91806264 5.700376 4.351315 2.995681 8.514658 8.533804 8.232333 AIFM2 1.020833448 0.043577906 0.011008506 17.91785111 9.354026 8.25747 6.636262 11.70801 12.556129 12.420795 EPHB3 1.076052742 0.043516135 0.00906771 17.90923325 3.024504 2.02348 2.379345 6.811341 7.187136 5.634184 LOC100506757 1.123150886 0.043453389 0.007488942 17.88712493 4.263463 2.406905 2.165421 8.139755 8.36819 6.32627 PIN4 1.097114387 0.04349335 0.00832392 17.88712493 1.874444 2.023048 2.165421 5.252045 6.319269 6.32627 SYTL1 1.051754884 0.043568903 0.009881592 17.88712493 1.874444 3.360637 2.165421 6.544171 6.489775 6.32627 MGC16142 1.211624664 0.043453389 0.005380061 17.87751803 1.874444 2.023048 2.165421 6.183122 7.094585 5.882028 C9orf53 1.080691902 0.043516135 0.008931609 17.87751803 1.874444 2.023048 2.165421 6.183122 7.56803 5.106393 LOC286177 1.002061546 0.043588662 0.011782919 17.87751803 2.201691 2.023048 3.90836 6.183122 7.406567 6.385515 CCBL2 0.977513586 0.043661316 0.012639673 17.87751803 1.874444 2.023048 2.165421 6.183122 7.269549 4.476242 MRPL1 0.905579442 0.044173537 0.016138142 17.87751803 1.874444 2.023048 2.165421 6.183122 6.549959 4.146207 DYNLT3 0.972505431 0.043681142 0.012872406 17.83614132 5.856559 3.872014 3.764125 9.058353 8.160956 7.920856 OSBPL9 1.038860997 0.043577906 0.01033753 17.83250093 4.263463 4.413323 3.764125 8.895478 8.4199 7.033813 PSMB10 1.141078847 0.043453389 0.007101055 17.80053164 1.874444 2.406905 2.165421 6.954147 6.319269 5.634184 ALG8 0.763861162 0.046215863 0.02456754 17.80053164 2.201691 2.023048 2.165421 7.937902 6.319269 2.921909 PION 0.969723309 0.043726704 0.012996257 17.79425588 3.024504 2.023048 2.165421 7.177844 6.319269 5.091834 LOC401324 0.95764687 0.043835088 0.013542021 17.78048138 5.744513 3.32135 3.935222 8.087444 8.579995 7.800057 GOLPH3L 0.864788918 0.044377262 0.018119769 17.75867877 2.993831 2.809601 2.165421 6.960054 7.31791 4.476242 CASP10 1.026874994 0.043577906 0.01068867 17.7564735 2.993831 2.023048 4.724406 7.144104 8.200916 7.033813 CEP63 1.130735036 0.043453389 0.007332426 17.71716601 4.682076 3.770995 3.90836 7.918071 8.2398 8.175185 ZNF33B 1.045905599 0.043577906 0.010134059 17.69117584 1.874444 3.360637 2.165421 7.037879 7.505595 5.426231 ARHGEF25 1.138403637 0.043453389 0.00718952 17.68612438 2.993831 2.809601 3.90836 6.954147 7.440337 7.748756 ACTR6 0.965744339 0.043778104 0.013153454 17.6860224 2.993831 2.406905 2.165421 7.25991 6.551443 5.091834 ZNF410 1.141867693 0.043453389 0.007060225 17.67849429 4.963444 4.830496 4.449894 8.974419 9.179013 8.25089 ALG9 0.916485713 0.044110923 0.015496427 17.67678914 4.743564 2.406905 2.165421 6.550689 6.549959 7.523109 NSDHL 1.098643214 0.04349335 0.008242259 17.6678456 2.993831 2.406905 2.165421 8.361545 6.549959 5.874974 CHCHD7 1.095211142 0.04349335 0.008412385 17.6678456 3.024504 2.406905 2.165421 7.856887 6.549959 5.882028 DKFZP564C196 1.045705848 0.043577906 0.010140864 17.661246 6.52121 4.736586 5.974145 9.012327 10.11666 10.32408 ZSCAN29 1.152921992 0.043453389 0.006781218 17.59710875 3.024504 2.406905 2.379345 6.544171 6.373501 7.180104 NUP160 1.170373965 0.043453389 0.006420551 17.58601318 4.743564 4.80797 4.449894 8.286188 8.87992 9.143346 LOC400950 1.103771933 0.04349335 0.008085743 17.58587823 4.209882 2.023048 3.324375 6.960054 8.296229 7.46072 ZNF3 1.201516935 0.043453389 0.005584212 17.54978763 2.201691 2.809601 2.165421 6.283686 6.608026 6.942983 HDGFRP3 0.982123427 0.043626235 0.012504253 17.54978763 4.639409 2.809601 2.379345 7.877571 6.794431 6.942983 FCF1 1.073693847 0.043516135 0.009128955 17.54440726 7.427999 6.228068 7.317525 10.039027 11.450464 12.464189 PRKCDBP 1.01493821 0.043581008 0.011273222 17.51604504 4.263463 3.360637 3.764125 6.664985 7.89473 8.456743 SUPV3L1 1.115154826 0.043485739 0.007731201 17.4808179 3.024504 3.872014 2.379345 7.074163 7.31791 7.152205 STOX2 0.984635598 0.043626235 0.012381763 17.4808179 3.024504 2.406905 2.165421 5.252045 6.551443 7.152205 C7orf73 1.072078285 0.043516135 0.009203811 17.45554299 4.682076 4.80797 3.90836 9.030914 8.033973 8.095288 RAB10 0.974640124 0.043661316 0.012755359 17.44816265 5.304463 4.389936 4.754917 9.615142 8.87992 7.428484 NUTF2 0.962056609 0.043778104 0.013289554 17.42365096 5.056948 3.360637 2.379345 9.179923 7.793829 6.385515 MIER1 1.004274033 0.043588662 0.011701259 17.3755482 2.993831 3.32135 3.324375 7.835902 7.440337 5.900694 HEMK1 1.176306876 0.043453389 0.006264035 17.36686186 1.874444 2.406905 2.165421 6.283686 6.551443 5.882028 RBBP5 1.121452265 0.043480953 0.007562436 17.36686186 2.201691 2.023048 2.165421 6.283686 5.509998 6.455366 EGF 1.061661786 0.043540291 0.009498469 17.36686186 1.874444 2.023048 2.165421 6.283686 6.189775 5.106393 LMOD3 1.057670449 0.043540291 0.009641375 17.36686186 1.874444 2.809601 2.165421 6.283686 7.174648 5.446557 RPAP3 1.029402941 0.043577906 0.010582511 17.36686186 3.350997 2.023048 2.165421 6.283686 6.205902 6.32627 TMEM8B 1.003944085 0.043588662 0.011708064 17.36686186 1.874444 2.023048 2.165421 6.283686 6.189775 4.790662 BOLA3 1.122661383 0.043480953 0.007521606 17.35784487 3.839948 3.770995 2.165421 7.957464 7.191402 7.492252 TXNDC11 1.032257244 0.043577906 0.010500851 17.33916214 4.682076 2.023048 3.324375 7.70315 7.440337 7.291822 ALDH1A1 1.018152868 0.043577906 0.011137802 17.32129403 3.024504 2.023048 2.379345 5.252.45 7.138979 6.931222 C14orf28 0.985293726 0.043626235 0.012347737 17.32103992 2.201691 2.809601 2.165421 5.026959 6.613395 6.924055 PON3 1.054290233 0.043568903 0.009779517 17.30895205 1.874444 2.023048 3.764125 7.877571 6.774676 5.874974 GALNT7 0.977794966 0.043661316 0.012619258 17.29991328 4.263463 3.32135 2.165421 8.376156 6.861783 6.455366 KIAA1279 0.776328525 0.045884853 0.023623682 17.29346193 1.874444 2.023048 2.995681 6.244586 7.107836 3.630092 AFF3 0.975830326 0.043661316 0.012700919 17.27215586 3.024504 2.023048 5.018694 9.12907 7.094585 6.69026 COMMD3 1.178041021 0.043453389 0.00623001 17.22413491 1.874444 2.023048 2.165421 5.705318 6.640994 6.129407 LOC653061 1.177635024 0.043453389 0.006236815 17.22413491 1.874444 2.023048 2.165421 5.728038 7.25505 6.129407 METTL20 1.174550244 0.043453389 0.006298061 17.22413491 1.874444 2.023048 2.165421 5.705318 7.191402 6.129407 FAM82B 1.088006657 0.043516135 0.00868935 17.22413491 1.874444 2.023048 2.995681 7.243046 5.857745 6.129407 PGAP2 1.013167333 0.043581008 0.011341273 17.22413491 2.201691 2.023048 3.764125 6.954147 6.549959 6.129407 RHOH 0.996939492 0.043626235 0.011951684 17.22413491 1.874444 2.023048 2.165421 7.450526 4.608763 6.129407 OLAH 0.966608624 0.043778104 0.013126233 17.22413491 1.874444 2.023048 2.165421 6.550689 4.539173 6.129407 KRIT1 0.736819334 0.047171086 0.026613134 17.22413491 1.874444 2.023048 2.165421 2.820813 7.138979 6.129407 CNTN1 0.916069568 0.044110923 0.015537258 17.2128895 1.874444 2.023048 4.724406 6.954147 8.829823 5.426231 SLC25A15 1.169440615 0.043453389 0.006434161 17.1972946 4.209882 3.360637 3.324375 7.877571 8.200916 7.428484 CXorf21 1.094500154 0.04349335 0.008425995 17.19423849 3.819732 3.32135 4.754917 7.177844 8.696398 8.858771 SNHG12 1.023249774 0.043577906 0.010892821 17.17283706 3.819732 4.351315 5.389265 10.140938 8.453372 7.582913 IFT81 1.095415832 0.04349335 0.008398775 17.12788729 3.819732 2.023048 3.324375 7.42265 7.870158 6.618407 CENPN 1.08065566 0.043516135 0.008938414 17.0998926 4.309025 5.43468 4.449894 8.40494 8.904331 8.593895 XKR5 0.990197007 0.043626235 0.012177611 17.09909288 4.682076 3.360637 5.596986 7.582358 8.777924 9.33818 CEP68 1.026780782 0.043577906 0.01070228 17.06801449 5.304463 3.32135 4.508334 7.748771 8.258856 9.397686 IQCC 1.157917212 0.043453389 0.006672338 17.04075834 5.316227 5.661685 6.355801 9.403221 10.446718 10.233665 ITM2A 0.953404398 0.043857532 0.013749575 17.01258392 5.056948 5.195784 6.769247 9.284314 11.103027 8.549611 MITD1 1.21708174 0.043453389 0.005271181 16.99837624 1.874444 2.023048 2.165421 6.252746 6.205902 5.900694 NAA16 1.092329265 0.04349335 0.008521266 16.99837624 2.993831 2.023048 2.165421 6.252746 7.96603 5.874974 SNUPN 1.044975227 0.043577906 0.010174209 16.99837624 1.874444 2.406905 2.165421 6.252746 7.174648 5.091834 FAM82A2 0.876854231 0.044280042 0.017576046 16.99837624 2.201691 4.80797 2.165421 6.252746 6.861783 6.924055 FBXW7 1.077479668 0.043516135 0.00904049 16.98150388 3.024504 3.770995 2.995681 7.856887 7.505595 6.455366 CFDP1 1.033511375 0.043577906 0.01044641 16.97355658 3.024504 3.32135 2.165421 5.743334 7.406567 7.395512 LOC400550 1.175153213 0.043453389 0.00628445 16.95351964 1.874444 2.023048 2.165421 5.705318 6.794431 6.106561 SEPT14 1.10788162 0.043485739 0.007962572 16.95351964 1.874444 2.023048 2.165421 5.320955 7.174648 6.106561 LOC100130691 1.104692709 0.04349335 0.008051718 16.95351964 1.874444 2.023048 2.165421 5.320955 6.613395 6.106561 LOC375295 1.077042002 0.043516135 0.0090541 16.93801234 1.874444 2.023048 3.324375 5.448591 7.406567 7.36177 SERPINB1 1.088341873 0.043516135 0.00866213 16.93569515 2.201691 3.360637 2.165421 6.283686 6.237456 8.60836 TMCO4 1.172353068 0.043453389 0.006345696 16.90877224 3.350997 3.360637 2.165421 7.36523 7.440337 6.931222 C3orf27 1.152170919 0.043453389 0.006808438 16.90250726 1.874444 2.023048 2.165421 6.244586 6.189775 5.580533 NMI 1.147514463 0.043453389 0.006917319 16.90250726 2.201691 2.023048 2.165421 6.244586 6.861783 5.634184 SHROOM4 1.018763127 0.043577906 0.011110582 16.88604281 3.819732 3.360637 2.165421 6.063041 7.53715 7.897492 STL 1.108916413 0.043485739 0.007935352 16.85141865 5.304463 4.80797 4.724406 8.39062 10.132246 8.882768 CCL21 1.007211727 0.043588662 0.011578768 16.84770994 5.263699 3.32135 3.764125 7.976765 7.31791 9.33818 COA5 1.144095047 0.043453389 0.006992174 16.81917229 2.201691 2.023048 2.165421 7.531061 6.237456 5.634184 CDC14B 1.099903227 0.04349335 0.008228649 16.81917229 1.874444 2.406905 2.165421 6.857154 6.237456 5.446557 PTGFR 1.08773024 0.043516135 0.00870296 16.81917229 1.874444 2.023048 2.165421 5.252045 6.237456 6.195186 MCART6 1.039699887 0.043577906 0.01031031 16.81917229 2.201691 2.023048 2.165421 6.395481 6.237456 5.106393 PTCHD1 0.999938973 0.043603337 0.011855053 16.81917229 1.874444 2.809601 2.165421 7.25991 6.237456 5.091834 ROPN1 0.714613311 0.047877006 0.028352501 16.81917229 1.874444 2.023048 2.165421 6.183122 6.237456 2.921909 AIM1 0.925773265 0.04407613 0.015088125 16.81617232 2.993831 2.406905 3.764125 7.135902 7.138979 5.426231 SETDB2 1.02538999 0.043577906 0.01077033 16.80290348 3.839948 3.872014 3.935222 6.814118 7.942653 8.03232 LRRC58 1.107321989 0.04349335 0.008004083 16.76993027 5.335413 4.351315 4.449894 8.41912 9.042712 8.60836 UBR3 1.169193907 0.043453389 0.006447771 16.76965563 4.209882 3.770995 2.165421 7.771052 8.277663 7.695565 MDP1 1.203877633 0.043453389 0.005516162 16.69999651 1.874444 2.023048 2.165421 6.063041 5.936219 7.152205 NBN 1.027375254 0.043577906 0.010668255 16.69002952 4.963444 3.32135 3.764125 7.995811 7.713236 7.825039 ALG10B 1.167312777 0.043453389 0.006481797 16.68813024 4.209882 4.830496 4.449894 8.270632 9.053666 8.503924 DTWD2 1.163860821 0.043453389 0.006522627 16.62832223 3.350997 3.872014 3.935222 8.087444 7.406567 7.897492 MEX3B 1.023989483 0.043577906 0.010865601 16.58930513 3.024504 2.809601 2.165421 7.167419 6.861783 5.580533 TRIM72 1.080190174 0.043516135 0.008965635 16.57030064 3.839948 4.830496 5.225216 8.190235 9.275744 8.579284 LOC100132526 1.064051433 0.043516135 0.009421572 16.5526681 6.846868 6.537655 7.107458 9.978073 10.932507 11.15645 ZNF483 1.202798468 0.043453389 0.005556992 16.51799894 1.874444 2.023048 2.165421 6.960054 5.920411 6.051818 NT5DC1 1.179700715 0.043453389 0.006168765 16.51799894 1.874444 2.023048 2.165421 8.488001 5.920411 6.051818 DMRT2 1.161123687 0.043453389 0.006590677 16.51799894 1.874444 2.406905 2.165421 6.067497 5.920411 6.649696 FGF13 1.101245769 0.04349335 0.008181014 16.51799894 1.874444 2.809601 2.165421 6.954147 5.920411 6.051818 ATP8A1 1.050056505 0.043568903 0.009929228 16.51799894 1.874444 2.023048 3.764125 7.037879 5.920411 7.152205 BBS9 1.199031935 0.043453389 0.005713508 16.50063556 1.874444 2.023048 2.165421 6.067497 5.857745 6.32627 POSTN 1.117202388 0.043485739 0.007663151 16.50063556 1.874444 2.023048 2.165421 6.067497 10.589051 5.580533 KNTC1 0.957429356 0.043835088 0.013555631 16.50063556 1.874444 2.023048 2.165421 6.067497 4.539173 6.385515 FAM110B 0.903908649 0.044173537 0.016240218 16.50063556 4.209882 2.023048 2.165421 6.067497 6.373501 6.69026 LINC00339 0.820275383 0.045095391 0.020711807 16.50063556 1.874444 2.023048 2.165421 6.067497 6.373501 3.676349 LOC100506776 0.64300694 0.05194815 0.036164682 16.50063556 1.874444 2.023048 5.609945 6.067497 5.920411 6.106561 SKIV2L2 0.96795695 0.043738451 0.013061586 16.46869544 3.024504 4.413323 2.165421 7.582358 7.066159 6.455366 SUGT1 1.057495826 0.043540291 0.009654985 16.45957435 2.993831 2.809601 3.324375 7.36523 7.269549 6.106561 SHPRH 1.147351929 0.043453389 0.006924124 16.45530902 1.874444 2.023048 2.165421 5.579836 6.205902 6.129407 SLC30A6 1.117848363 0.043485739 0.007642736 16.45530902 1.874444 2.406905 2.165421 6.651882 6.205902 5.580533 CPEB3 1.106679069 0.04349335 0.008010888 16.45530902 2.201691 2.023048 2.165421 6.954147 6.205902 5.426231 MRPL35 1.206455171 0.043453389 0.005468527 16.44974648 1.874444 2.023048 2.165421 6.063041 5.936219 6.106561 GSTM4 1.196896227 0.043453389 0.005780878 16.44974648 1.874444 2.023048 2.165421 6.063041 5.857745 6.73963 LOC100506409 1.004361262 0.043588662 0.011694454 16.44974648 4.263463 2.023048 2.165421 6.063041 7.713236 7.020304 PTPN13 0.876132814 0.044280042 0.017610071 16.4310072 2.993831 4.80797 2.165421 6.252746 7.406567 7.03218 VSIG1 1.141241209 0.043453389 0.007087445 16.42853806 2.201691 2.406905 2.995681 6.183122 6.613395 7.033813 ADSS 0.950415548 0.043900827 0.013885675 16.4174094 3.819732 2.023048 3.764125 7.856887 7.066159 6.106561 NFIL3 1.091773068 0.0435113 0.008538959 16.37365648 6.678389 5.362142 7.401896 10.409498 10.711694 10.910165 CPN2 1.063794065 0.043516135 0.009428377 16.35045117 1.874444 4.80797 3.935222 7.679787 8.077554 7.96648 TGFBI 1.091375482 0.0435113 0.008572984 16.3502397 6.381847 5.148082 6.769247 10.59581 10.413087 9.697401 MYO5C 1.109900745 0.043485739 0.007908132 16.33353083 2.993831 2.809601 2.165421 8.460842 6.551443 6.195186 HDHD3 1.102868063 0.04349335 0.008112964 16.33353083 2.993831 2.023048 2.165421 7.144104 6.043524 6.195186 COQ9 1.058205558 0.043540291 0.009600544 16.33353083 2.993831 3.32135 2.165421 6.651882 7.56803 6.195186 VAMP7 1.024554446 0.043577906 0.01083838 16.33353083 3.819732 3.360637 2.165421 8.676869 7.094585 6.195186 NOL8 1.003790483 0.043588662 0.011714869 16.33353083 2.993831 2.023048 2.165421 7.679787 5.306419 6.195186 LPP-AS2 0.949875454 0.043900827 0.013899285 16.33353083 1.874444 2.023048 2.165421 6.063041 4.539173 6.195186 GAPT 1.173295554 0.043453389 0.006311671 16.32227493 1.874444 2.023048 2.165421 5.728038 6.319269 6.051818 RP11-165H20.1 1.165541036 0.043453389 0.006502212 16.32227493 1.874444 2.023048 2.165421 5.705318 7.174648 6.051818 STAR 1.15766408 0.043453389 0.006679143 16.32227493 1.874444 2.023048 2.379345 6.063041 5.920411 6.051818 IKZF1 1.042565168 0.043577906 0.010242259 16.29379656 1.874444 2.406905 2.995681 7.477873 5.920411 5.900694 MARC2 0.906765906 0.044173537 0.016063287 16.29379656 1.874444 2.023048 4.285996 6.252746 7.174648 5.900694 STAM 0.781616303 0.04575418 0.023207894 16.29379656 1.874444 2.023048 5.389265 6.664985 7.107836 5.900694 C2orf69 1.056540168 0.043540291 0.00968901 16.27239452 1.874444 2.809601 2.165421 8.139755 6.189775 5.446557 AMD1 0.955436986 0.043840967 0.013668595 16.2646502 4.682076 5.340619 6.769247 9.968463 9.426624 8.705744 MAOA 0.824368702 0.044949653 0.020444369 16.25930205 6.054828 4.351315 2.165421 8.935488 6.551443 8.374509 FBLN7 0.876668223 0.044280042 0.017589656 16.25525417 3.024504 3.770995 2.995681 5.252045 7.793829 7.428484 PLEKHH1 1.20095235 0.043453389 0.005625043 16.22870191 1.874444 2.023048 2.165421 6.396698 6.043524 5.882028 BLZF1 1.200025992 0.043453389 0.005693093 16.22870191 1.874444 2.023048 2.165421 6.252746 6.043524 5.882028 ABCB10 1.19196571 0.043453389 0.005916979 16.22870191 1.874444 2.023048 2.165421 7.210813 6.043524 5.882028 CD84 1.172599763 0.043453389 0.006338891 16.22870191 1.874444 2.023048 2.165421 5.728038 6.043524 6.32627 LOC100129518 1.145188445 0.043453389 0.006964954 16.22870191 1.874444 2.023048 2.165421 5.579836 6.043524 6.385515 TMEM144 1.123125975 0.043453389 0.007502552 16.22870191 1.874444 2.023048 2.165421 5.448591 6.043524 6.722123 OCIAD2 1.111782801 0.043485739 0.007853692 16.22870191 1.874444 2.023048 2.165421 8.811966 6.043524 5.446557 SHANK2 1.067789003 0.043516135 0.009319496 16.22870191 1.874444 2.023048 2.165421 7.877571 6.043524 5.106393 F8 1.062852533 0.043516135 0.009455597 16.22870191 1.874444 2.023048 2.165421 5.095353 6.043524 6.931222 C11orf1 1.022686914 0.043577906 0.010926846 16.22870191 1.874444 2.023048 2.165421 8.222933 6.043524 4.790662 UNG 1.015231021 0.043581008 0.011246002 16.22870191 1.874444 2.023048 2.165421 4.802615 6.043524 7.033813 C12orf26 0.98898028 0.043626235 0.012218442 16.22870191 1.874444 2.023048 2.165421 4.718672 6.043524 6.455366 C5 0.943766096 0.043921714 0.014197346 16.22870191 1.874444 2.023048 2.165421 6.339437 6.043524 4.476242 HSD17B2 0.907039354 0.044173537 0.016049677 16.22870191 1.874444 2.023048 2.165421 6.857154 6.043524 4.146207 HEBP1 0.742134994 0.046946487 0.02618986 16.22870191 1.874444 2.023048 2.379345 7.556937 6.043524 2.921909 TPTE2P6 1.201064883 0.043453389 0.005618237 16.19752558 1.874444 2.023048 2.165421 6.183122 5.857745 6.129407 WDR70 1.10347609 0.04349335 0.008092548 16.19752558 2.201691 2.023048 2.165421 6.183122 6.774676 5.426231 GNAI1 1.046293932 0.043577906 0.010106839 16.19752558 2.201691 2.023048 2.165421 6.183122 6.794431 5.106393 UQCRB 0.918388332 0.044110923 0.015403879 16.19752558 3.819732 2.023048 2.165421 6.183122 6.205902 6.106561 MKRN2 1.183024864 0.043453389 0.006093909 16.19361071 2.201691 2.406905 2.379345 6.396698 6.794431 6.051818 KLF10 1.106381225 0.04349335 0.008017693 16.1895139 5.335413 6.311907 5.974145 9.352401 10.463244 9.951121 TIAL1 1.023983311 0.043577906 0.010872406 16.18762743 5.328526 4.911517 3.90836 9.352401 8.928336 7.748756 GTF2F2 0.822099892 0.045048325 0.020604287 16.1872899 1.874444 4.750708 2.379345 5.891233 6.774676 6.587378 C1orf210 1.105557384 0.04349335 0.008031303 16.17995492 1.874444 2.023048 2.379345 6.395481 6.237456 5.446557 SDAD1 0.91352748 0.044110923 0.015686968 16.17995492 2.993831 2.023048 2.379345 6.395481 7.066159 4.790662 ARL1 0.988134533 0.043626235 0.012252467 16.11698423 5.753024 4.80797 3.764125 9.314972 9.009341 7.774634 CLDN3 0.793855018 0.04542938 0.022433481 16.11698423 5.304463 7.598777 3.764125 10.492308 9.339793 7.774634 FAM13C 1.042909218 0.043577906 0.010221844 16.10357514 3.024504 2.406905 4.285996 8.254907 6.774676 7.033813 LOC100506844 1.178589353 0.043453389 0.00620279 16.08433297 1.874444 2.023048 2.165421 5.891233 6.613395 5.882028 IFIT2 1.17744273 0.043453389 0.00624362 16.08433297 1.874444 2.023048 2.165421 7.037879 5.920411 5.882028 GLRX2 1.084152457 0.043516135 0.008798231 16.08433297 1.874444 2.809601 2.165421 6.252746 6.189775 5.882028 ZNF720 1.024183313 0.043577906 0.010858796 16.08433297 1.874444 2.023048 3.324375 6.244586 6.551443 5.882028 STK36 1.015306467 0.043581008 0.011239197 16.08433297 1.874444 2.023048 3.935222 6.960054 7.191402 5.882028 EZH2 0.942225446 0.043921714 0.014285812 16.08433297 1.874444 3.32135 4.449894 7.877571 7.819723 5.882028 FAM65B 1.096605198 0.04349335 0.008344335 16.08262456 3.839948 2.023048 3.935222 6.960054 7.942653 7.800057 MGC34034 1.108719884 0.043485739 0.007942157 16.06522034 2.201691 3.32135 2.165421 6.067497 6.78473 7.327219 ICK 0.974907063 0.043661316 0.012748554 16.05101743 1.874444 3.360637 2.165421 7.36523 6.78473 5.091834 SUSD3 1.070154257 0.043516135 0.009244641 16.04677342 2.201691 2.406905 2.165421 5.448591 6.205902 6.587378 HMGN2 1.11339629 0.043485739 0.007806056 16.01930674 2.201691 2.809601 2.165421 6.811341 5.857745 6.455366 COL4A5 0.680985882 0.049464555 0.031548146 16.01930674 1.874444 2.809601 2.379345 6.811341 6.549959 2.921909 MCTP2 1.159091449 0.043453389 0.006638312 16.01729401 3.350997 3.770995 3.324375 7.995811 7.269549 7.352555 PRKG1 1.142078156 0.043453389 0.007046614 16.00588013 1.874444 2.023048 2.995681 6.954147 6.794431 5.874974 CSRNP3 1.130917009 0.043453389 0.007318816 16.00588013 1.874444 2.406905 2.165421 5.891233 6.608026 5.874974 TIFA 1.113770163 0.043485739 0.007792446 16.00588013 1.874444 2.406905 2.379345 6.664985 5.936219 5.874974 MARVELD2 1.078696107 0.043516135 0.00901327 16.00588013 1.874444 2.023048 3.324375 6.811341 6.774676 5.874974 H1FX 0.842492791 0.044657496 0.019273903 15.97792757 8.234634 5.43468 6.369239 9.60897 10.404555 10.367248 LINC00476 1.061625485 0.043540291 0.009505274 15.95235121 5.263699 4.389936 2.995681 8.105092 8.385634 8.593895 NME7 1.059726218 0.043540291 0.009539299 15.94326401 3.819732 2.406905 2.995681 7.814607 7.713236 6.129407 BVES 1.018186264 0.043577906 0.011130997 15.93531826 1.874444 2.406905 2.379345 5.026959 6.373501 6.924055 LINC00092 1.114797282 0.043485739 0.007751616 15.87379945 2.993831 2.406905 2.165421 6.395481 7.598264 6.106561 HELQ 1.084701096 0.043516135 0.008784621 15.87379945 3.350997 2.406905 2.165421 6.395481 6.373501 7.033813 RPS6KA1 1.027802355 0.043577906 0.010634229 15.86840013 2.201691 2.809601 2.165421 7.42265 6.189775 5.426231 PDZD9 0.915332976 0.044110923 0.015564478 15.86840013 2.201691 2.023048 3.324375 5.026959 6.189775 7.36177 SAR1B 1.018526872 0.043577906 0.011124192 15.85871066 4.309025 4.750708 3.90836 9.307369 8.296229 7.218312 CIZ1 0.914353585 0.044110923 0.015625723 15.84954932 4.209882 3.360637 3.90836 8.553743 7.89473 6.051818 SGCE 1.032146207 0.043577906 0.010507656 15.83861524 4.815804 4.911517 6.601009 8.801178 10.369915 9.438736 CRYL1 0.779930703 0.045824482 0.023329704 15.83263961 1.874444 2.809601 2.165421 6.396698 6.794431 3.630092 PPP1R1A 1.103246763 0.04349335 0.008099354 15.83059 3.350997 2.023048 2.165421 7.33564 5.920411 6.942983 LOC729678 1.171160778 0.043453389 0.006379721 15.82441302 3.024504 3.32135 3.324375 7.30543 7.414086 6.924055 UVRAG 0.91858925 0.044110923 0.015390269 15.81587015 1.874444 4.351315 2.995681 7.177844 5.857745 7.492252 CP 0.911082034 0.044159136 0.01583804 15.81587015 1.874444 3.360637 3.935222 8.875048 5.857745 6.32627 TLN1 0.916199807 0.044110923 0.015516842 15.81092502 5.316227 5.362142 5.571599 9.344992 9.687973 7.748756 B4GALT4 0.678088573 0.049604445 0.031832596 15.79538996 2.201691 2.406905 2.165421 6.183122 6.613395 2.921909 MRPS14 0.828545961 0.044930476 0.020223205 15.79127519 2.993831 2.809601 3.324375 7.30543 7.094585 4.790662 MRPL22 0.890298043 0.044203301 0.016985369 15.77725776 3.839948 2.023048 4.754917 8.122528 7.819723 6.051818 KATNA1 1.109694033 0.043485739 0.007928547 15.76452689 3.024504 2.406905 3.324375 6.954147 7.819723 6.385515 KCTD9 1.088737307 0.043516135 0.00864852 15.75799488 4.743564 4.413323 5.544653 9.260886 8.97518 8.391335 DHTKD1 0.998794091 0.043626235 0.011876829 15.7533036 5.056948 3.872014 2.379345 7.36523 8.200916 7.849596 ABTB1 0.942772995 0.043921714 0.014265396 15.7412592 4.682076 2.023048 3.764125 6.283686 7.740604 8.407967 ARHGEF26 1.007251376 0.043588662 0.011565158 15.72516028 3.350997 3.360637 2.165421 7.33564 6.205902 6.649696 EHD4 1.023509858 0.043577906 0.010886016 15.70619277 3.819732 2.023048 2.165421 7.792994 7.138979 5.634184 CD24 0.808664443 0.045247607 0.021461722 15.69113752 6.924263 9.104741 5.596986 13.076619 11.071037 9.061607 ALDH7A1 1.059645933 0.043540291 0.009552909 15.68581543 5.328526 4.80797 3.764125 8.779359 9.218487 8.010706 SPTLC1 0.777757634 0.045844227 0.023471249 15.68368311 4.209882 2.809601 2.165421 6.811341 8.181074 4.562324 DDX50 0.67203473 0.049993148 0.032517183 15.63379178 2.201691 2.406905 2.165421 6.283686 6.373501 2.921909 MRPL50 0.94340021 0.043921714 0.014224566 15.61731819 1.874444 2.809601 2.165421 6.283686 6.774676 4.790662 CORO1C 1.128621809 0.043453389 0.007366451 15.61535602 2.201691 4.389936 4.285996 7.748771 8.296229 8.25089 NGDN 1.094045272 0.04349335 0.008439605 15.60902004 4.639409 4.389936 4.508334 7.814607 8.986657 8.472642 ADH1B 0.99339247 0.043626235 0.012068731 15.60447739 4.743564 3.872014 6.072169 7.835902 9.188984 9.922465 CA5B 0.995051845 0.043626235 0.012034706 15.58823665 6.186289 4.736586 6.450701 8.734704 10.413087 10.070856 LOC100128071 0.995972401 0.043626235 0.011993875 15.58601781 4.743564 2.406905 4.285996 7.70315 7.191402 8.705744 EBP 1.100867876 0.04349335 0.008187819 15.54594117 1.874444 2.809601 2.995681 6.954147 6.549959 6.195186 FBXL19-AS1 1.063135817 0.043516135 0.009435182 15.53774345 8.129608 7.786385 7.884888 11.107978 12.316817 11.842593 PFDN5 1.010186089 0.043581008 0.011429738 15.47039008 6.617556 6.42919 7.156853 10.706903 11.108291 9.649245 GPR172A 0.855713734 0.044416666 0.018571623 15.42208119 5.304463 3.770995 2.379345 8.033165 7.989035 6.32627 ACADSB 1.12379237 0.043453389 0.007468527 15.40392692 5.856559 5.362142 3.764125 9.307369 9.266358 9.430619 RNF31 0.916275239 0.044110923 0.015510037 15.37209431 3.024504 3.770995 4.449894 6.063041 7.713236 8.822008 DBT 1.12233991 0.043480953 0.007528411 15.36463959 4.209882 5.297868 5.592916 8.811966 9.484439 9.23941 DYNLT1 0.995517476 0.043626235 0.012014291 15.36035749 3.024504 4.389936 2.165421 7.679787 8.077554 6.106561 XPA 0.986050683 0.043626235 0.012334127 15.36035749 2.201691 2.023048 2.165421 4.894482 6.189775 6.106561 ACAT2 1.10226965 0.04349335 0.008126574 15.34742142 2.993831 2.023048 2.379345 6.814118 6.319269 6.106561 TMEM110 1.042187686 0.043577906 0.010249064 15.34742142 1.874444 3.32135 2.379345 6.664985 6.319269 6.106561 ERI2 0.922509057 0.044091888 0.015225587 15.34742142 1.874444 2.023048 2.379345 6.067497 6.319269 4.476242 LMBRD1 0.863932642 0.044377262 0.018164682 15.34742142 1.874444 2.809601 2.379345 7.814607 6.319269 4.146207 IL2 0.926206997 0.04406867 0.01504049 15.30080031 1.874444 2.023048 3.324375 7.25991 6.551443 4.790662 DHX16 0.891621106 0.044203301 0.016924124 15.28134145 5.056948 3.32135 2.379345 6.857154 7.25505 7.428484 EEF1E1 0.672534904 0.049933984 0.032419871 15.28134145 1.874444 3.32135 2.165421 6.550689 7.25505 2.921909 ARGLU1 0.968033541 0.043738451 0.013047976 15.27527206 5.700376 5.43468 6.031658 9.633502 10.24167 8.357484 LOC100132352 1.073780256 0.043516135 0.00912215 15.2689873 2.993831 2.406905 2.165421 6.339437 7.138979 5.900694 ACPP 1.097258815 0.04349335 0.008317115 15.2637082 4.963444 5.362142 6.012527 8.895478 9.749902 9.67008 C11orf63 1.109861953 0.043485739 0.007914937 15.26310806 6.008206 6.391145 6.282905 9.621288 10.72546 10.214881 MPL 1.075897604 0.043516135 0.009074515 15.26216166 4.263463 3.360637 3.324375 7.243046 7.292524 8.440667 AP3B1 0.988363424 0.043626235 0.012245662 15.26216166 3.839948 3.360637 2.165421 8.346785 7.292524 5.882028 LYPLA1 0.930621252 0.044025007 0.014784621 15.26216166 4.309025 3.360637 2.379345 8.566539 7.292524 5.874974 P2RY8 1.046390045 0.043577906 0.010093229 15.25473049 1.874444 3.360637 2.995681 6.550689 6.237456 7.291822 LOC100130872 1.081678059 0.043516135 0.008877169 15.24934087 3.024504 2.023048 3.324375 6.814118 7.25505 6.32627 KIAA1324 0.876947813 0.044280042 0.017569241 15.2409551 2.993831 6.228068 5.389265 10.157949 8.855089 7.395512 ARHGEF7 1.041393143 0.043577906 0.010262674 15.24035342 6.099991 6.139057 6.031658 10.029816 9.075328 10.924687 GABARAPL2 1.093851028 0.04349335 0.00844641 15.23974469 5.328526 4.80797 2.995681 9.102956 8.737737 8.32282 CDON 0.993158488 0.043626235 0.012089146 15.21810394 2.201691 2.023048 2.379345 4.894482 7.25505 6.129407 BBS1 1.100753942 0.04349335 0.008215039 15.15472702 2.201691 3.32135 2.995681 7.243046 6.549959 6.69026 CLEC2D 0.845499903 0.044641179 0.019145968 15.15219467 4.743564 3.32135 6.450701 8.665019 9.608485 7.291822 EPB41L5 0.891191139 0.044203301 0.016944539 15.13026614 3.024504 2.406905 4.754917 8.711848 6.549959 6.32627 CNOT2 0.907307763 0.044173537 0.016036067 15.11027913 2.993831 4.750708 6.012527 9.171571 8.668166 7.46072 CYP27C1 0.933420351 0.044025007 0.01467574 15.08371432 3.839948 4.413323 4.285996 6.550689 8.200916 8.732403 MRPS28 1.140216094 0.043453389 0.007155495 15.06544747 1.874444 2.023048 2.165421 7.167419 5.936219 5.634184 NEK3 1.116947249 0.043485739 0.007683566 15.06544747 1.874444 2.023048 2.379345 6.857154 5.936219 5.634184 MRPS17 1.056231906 0.043540291 0.009723035 15.06544747 1.874444 2.023048 2.165421 7.177844 5.936219 5.106393 SPTSSB 1.054192823 0.043568903 0.009793127 15.06544747 1.874444 2.023048 2.165421 6.814118 5.936219 5.106393 INE1 0.989526311 0.043626235 0.012191222 15.06544747 1.874444 2.023048 2.165421 6.283686 5.936219 4.790662 FNBP1L 0.957201121 0.043835088 0.013562436 15.06544747 1.874444 2.023048 2.165421 7.177844 5.936219 4.476242 NEK10 0.906074446 0.044173537 0.016097312 15.06544747 1.874444 2.023048 2.165421 4.341916 5.936219 6.106561 ATP5EP2 0.869137359 0.044335719 0.017915618 15.06544747 1.874444 2.023048 2.165421 8.540832 5.936219 3.676349 LOC389493 0.800678786 0.045343936 0.021938755 15.06544747 1.874444 2.023048 2.165421 6.244586 5.936219 3.630092 RNF39 0.749384944 0.04671806 0.025669956 15.06544747 1.874444 2.023048 2.165421 7.477873 5.936219 2.921909 ZNF92 0.747630928 0.046782073 0.025801973 15.06544747 1.874444 2.023048 2.165421 7.42265 5.936219 2.921909 L1TD1 0.702022973 0.048553714 0.029645458 15.06544747 1.874444 2.023048 2.165421 6.244586 5.936219 2.921909 CBX3 1.066499318 0.043516135 0.009360327 15.06348089 5.491121 6.044198 5.702912 10.351527 9.615895 8.974957 GREB1 0.933590882 0.044025007 0.01464852 15.05866404 2.201691 2.809601 4.285996 6.814118 6.551443 6.722123 ATF7IP2 0.712023892 0.0479972 0.028583192 15.05866404 3.024504 2.809601 6.054038 7.25991 7.066159 6.722123 KIAA1797 1.084708438 0.043516135 0.008777816 15.05701907 2.993831 2.406905 2.165421 6.550689 6.319269 6.106561 PCOLCE 0.909519107 0.044173036 0.015939435 15.05480822 4.209882 5.43468 6.601009 8.173604 9.860086 9.346832 PHKB 1.145669497 0.043453389 0.006958149 15.04055951 4.815804 4.80797 4.508334 8.41912 8.97518 8.519314 ZNF22 0.948332618 0.043900827 0.013974141 15.02944361 4.682076 2.809601 2.995681 8.591796 8.119857 5.882028 MAP3K8 1.097546007 0.04349335 0.008289895 15.02103452 3.819732 3.360637 3.935222 8.864724 7.269549 7.395512 GNPNAT1 0.971790749 0.043681142 0.012906431 15.01978267 1.874444 3.770995 2.379345 7.679787 5.936219 6.129407 SLIT3 1.069585236 0.043516135 0.009271861 15.0145002 4.815804 3.32135 5.225216 8.173604 8.724089 8.784285 TMEM25 1.09245722 0.04349335 0.008507656 14.99763573 5.056948 4.750708 5.702912 9.252991 8.963611 8.70819 GPR116 0.962137188 0.043778104 0.013282749 14.9933165 5.328526 3.360637 3.90836 7.814607 7.138979 9.899123 PPM1K 1.122244487 0.043480953 0.007535216 14.97900623 2.201691 2.023048 2.379345 5.705318 6.613395 6.106561 C1orf122 0.889558756 0.044203301 0.017019394 14.97900623 2.201691 4.351315 4.754917 8.895478 7.96603 6.106561 CES1P1 0.913758341 0.044110923 0.015673358 14.97555838 3.350997 2.406905 2.379345 4.894482 7.107836 7.255535 LINC00294 0.982376304 0.043626235 0.012490643 14.97449355 5.856559 4.736586 6.355801 8.641022 9.809281 9.894518 FAM179B 0.98371443 0.043626235 0.012415788 14.97052598 3.350997 2.023048 2.165421 5.252045 7.25505 6.722123 DTWD1 0.969813435 0.043726704 0.012989452 14.92387811 3.024504 2.406905 4.508334 6.550689 8.160956 6.924055 PLS3 1.089569628 0.043516135 0.00860769 14.91857584 2.201691 3.872014 2.379345 7.771052 7.713236 6.051818 CHM 1.079454559 0.043516135 0.008979245 14.90976367 5.897292 4.389936 4.724406 8.254907 9.563208 9.795477 LOC440028 1.091750436 0.0435113 0.008545764 14.90392508 2.201691 2.023048 2.165421 6.063041 7.656894 5.426231 CABP4 1.021166109 0.043577906 0.010981286 14.90392508 1.874444 3.32135 2.165421 6.063041 6.043524 6.618407 CD200 1.008071429 0.043581008 0.011518203 14.90392508 2.201691 3.360637 2.165421 6.063041 6.319269 6.32627 TSLP 0.681896925 0.049428793 0.031493025 14.90392508 2.201691 2.023048 2.165421 6.063041 6.205902 2.921909 ATG10 1.133527843 0.043453389 0.007250766 14.9012633 1.874444 2.023048 2.165421 6.395481 5.920411 5.580533 COX7A2L 1.105200863 0.04349335 0.008044913 14.9012633 1.874444 2.023048 2.165421 5.448591 5.920411 6.106561 C2orf77 1.070094806 0.043516135 0.009251446 14.9012633 1.874444 2.023048 2.165421 5.252045 5.920411 6.195186 EYS 1.051232855 0.043568903 0.009895202 14.9012633 1.874444 2.023048 2.165421 6.651882 5.920411 5.106393 IGSF1 1.008254721 0.043581008 0.011484178 14.9012633 1.874444 2.023048 2.165421 7.607339 5.920411 4.790662 ESRP1 1.007343243 0.043588662 0.011551548 14.9012633 1.874444 2.023048 2.165421 7.477873 5.920411 4.790662 HMGCS2 0.944793283 0.043921714 0.014149711 14.9012633 1.874444 2.023048 2.165421 10.70979 5.920411 4.146207 RAMP3 0.929852912 0.044037172 0.014820687 14.9012633 1.874444 2.023048 3.935222 5.579836 5.920411 8.534542 LZIC 0.906097767 0.044173537 0.016090507 14.9012633 1.874444 2.023048 2.165421 7.167419 5.920411 4.146207 CD40LG 0.880465417 0.044278935 0.017429058 14.9012633 1.874444 2.023048 2.165421 6.283686 5.920411 4.146207 LOC100505718 0.738165652 0.047140798 0.026539639 14.9012633 1.874444 2.023048 2.165421 7.167419 5.920411 2.921909 COQ3 0.705498815 0.048378239 0.029294998 14.9012633 1.874444 2.023048 2.165421 6.339437 5.920411 2.921909 LOC645212 1.084083159 0.043516135 0.008811841 14.89711874 4.209882 3.32135 3.324375 7.877571 7.414086 7.218312 TMEM208 0.840841224 0.044701668 0.019433141 14.87582306 5.304463 3.360637 2.165421 7.607339 6.549959 7.255535 SPOPL 0.952030919 0.043900827 0.013817625 14.87082418 2.201691 3.360637 4.944468 8.40494 7.25505 6.73963 C8orf45 0.946777657 0.043900827 0.014055801 14.87082418 4.639409 3.360637 2.165421 6.857154 7.25505 7.291822 NAMPT 1.095043344 0.04349335 0.00841919 14.84932626 7.641685 6.270596 6.450701 11.483507 10.162922 11.276797 C14orf159 1.107740283 0.043485739 0.007969377 14.84648683 3.350997 2.406905 3.324375 7.243046 7.174648 6.618407 C14orf23 0.960177616 0.043802358 0.013392991 14.82074755 5.263699 3.360637 4.508334 7.177844 8.402869 9.153246 FERMT3 0.888585195 0.044203301 0.017073835 14.81707367 4.209882 2.023048 4.285996 5.743334 8.119857 8.175185 SPATA7 1.080032193 0.043516135 0.00897244 14.78843233 1.874444 2.023048 2.165421 5.320955 5.936219 6.051818 RWDD3 1.019658474 0.043577906 0.011056142 14.78843233 2.201691 2.023048 2.165421 5.026959 6.640994 6.051818 PEX19 0.765904251 0.046178907 0.024413066 14.78843233 5.700376 3.32135 2.165421 7.30543 7.96603 6.051818 TPTE2P1 1.008448006 0.043581008 0.011463763 14.74759853 7.392123 7.106065 7.250844 10.174762 11.149721 11.274531 A2M 0.953829485 0.043857532 0.01371555 14.73474231 6.554045 6.228068 6.919905 9.196483 10.450867 10.801055 DEF6 1.042854013 0.043577906 0.010228649 14.72972682 3.839948 2.809601 2.379345 7.582358 6.549959 6.69026 F11R 1.005529275 0.043588662 0.011633209 14.71116825 5.304463 6.060401 3.324375 9.939241 8.764653 8.519314 SFMBT2 1.039530845 0.043577906 0.010317115 14.70365259 2.201691 2.023048 2.165421 7.995811 6.043524 5.091834 FAM107A 1.007288843 0.043588662 0.011558353 14.70365259 3.350997 3.32135 2.165421 6.498222 6.043524 10.265959 FH 0.965384678 0.043778104 0.013180674 14.70365259 2.201691 2.023048 2.165421 8.190235 6.043524 4.562324 MPEG1 0.786950329 0.045564387 0.022815924 14.70365259 2.201691 2.023048 2.165421 6.244586 6.043524 3.676349 FAT3 1.171925002 0.043453389 0.006366111 14.69900523 1.874444 2.023048 2.165421 5.891233 5.920411 5.900694 ATP1A2 1.127206025 0.043453389 0.007414086 14.69900523 1.874444 2.023048 2.379345 5.728038 6.794431 5.900694 UBAC2 1.127089011 0.043453389 0.007420891 14.69900523 1.874444 2.023048 2.379345 5.728038 6.608026 5.900694 REP15 1.086761093 0.043516135 0.00871657 14.69900523 1.874444 2.023048 2.165421 5.320955 7.174648 5.900694 THEMIS 1.084339722 0.043516135 0.008791426 14.69900523 1.874444 2.023048 2.165421 7.771052 5.317867 5.900694 RBMX 1.062869837 0.043516135 0.009448792 14.69900523 1.874444 2.023048 2.379345 6.954147 5.317867 5.900694 SLC35F3 1.058130996 0.043540291 0.009607349 14.69900523 1.874444 2.023048 2.165421 6.498222 5.165949 5.900694 ZNF821 0.968907424 0.043738451 0.013034365 14.69900523 3.839948 2.023048 2.165421 6.244586 7.440337 5.900694 TTC18 0.910744523 0.044159136 0.01585165 14.69900523 2.201691 2.023048 3.764125 6.244586 6.205902 5.900694 MUC21 0.855239925 0.044416666 0.018585233 14.69900523 1.874444 2.023048 2.165421 4.013424 6.205902 5.900694 DYRK4 0.787842675 0.045562713 0.0227574 14.69900523 4.639409 2.023048 2.165421 6.067497 6.551443 5.900694 TMPRSS13 1.021230132 0.043577906 0.010974481 14.69018878 1.874444 2.406905 2.165421 6.283686 6.205902 5.106393 DST 1.002367366 0.043588662 0.011762504 14.68173311 5.316227 7.197097 5.571599 10.110676 10.701282 9.192178 ACTB 0.883471677 0.044229452 0.017304525 14.68146335 5.982974 6.762934 4.449894 10.638857 8.486085 9.103055 RUNX1T1 0.724769831 0.047575442 0.027518884 14.67419411 5.056948 3.770995 5.571599 5.705318 9.1177 9.446808 HCG22 1.023243968 0.043577906 0.010899626 14.61464827 2.201691 3.770995 2.165421 5.579836 7.406567 7.640338 LCOR 0.981570763 0.043626235 0.012517863 14.61464827 3.350997 3.770995 4.944468 8.222933 7.31791 7.640338 KIAA1731 1.155743353 0.043453389 0.006726778 14.61006678 1.874444 2.023048 2.165421 5.743334 6.613395 5.882028 LOC100132987 1.153432242 0.043453389 0.006767608 14.61006678 1.874444 2.023048 2.165421 5.743334 5.857745 6.106561 POP5 1.002247453 0.043588662 0.011769309 14.61006678 1.874444 3.32135 2.165421 5.743334 7.066159 6.051818 C10orf58 0.882850966 0.044229452 0.01732494 14.6070175 6.054828 3.872014 4.285996 8.433162 7.740604 8.472642 IFT46 1.13054837 0.043453389 0.007339231 14.60292315 2.201691 2.023048 2.379345 5.891233 5.936219 6.931222 NCKAP5 1.08518875 0.043516135 0.008750595 14.60292315 1.874444 2.023048 2.165421 5.891233 5.317867 6.69026 LY86-AS1 1.055465856 0.043540291 0.00975706 14.60292315 2.201691 2.023048 2.995681 5.891233 6.608026 6.106561 TRMT11 1.039317854 0.043577906 0.01032392 14.60292315 1.874444 2.023048 2.165421 5.891233 6.237456 5.091834 VCPIP1 0.945616065 0.043921714 0.014115686 14.60292315 1.874444 2.023048 2.165421 5.891233 6.237456 4.562324 LEKR1 0.795967407 0.045374706 0.022247703 14.60292315 1.874444 2.023048 2.165421 5.891233 6.043524 3.676349 CMAS 0.87828841 0.044280042 0.017521606 14.60056002 2.993831 2.023048 2.165421 6.244586 6.861783 4.562324 CLSTN1 1.065102349 0.043516135 0.009387547 14.59745244 5.982974 5.195784 5.389265 8.875048 9.25691 10.421501 TCEAL1 0.901285671 0.044203301 0.016394012 14.5818471 1.874444 2.406905 2.995681 6.814118 6.861783 4.562324 CCDC163P 0.764010394 0.046193441 0.024534195 14.57886787 2.201691 4.750708 2.165421 6.067497 6.043524 6.385515 RPL11 1.084852853 0.043516135 0.0087574 14.57725795 10.655041 10.67631 11.046193 14.200262 14.541958 15.032296 N4BP2L2 1.08901281 0.043516135 0.00863491 14.55529887 5.335413 2.023048 4.944468 8.501391 9.198885 8.636861 SCAF8 1.11436828 0.043485739 0.007772031 14.54742582 2.993831 3.872014 3.90836 7.771052 7.406567 7.46072 ZHX1 0.91762084 0.044110923 0.015441987 14.53513991 4.263463 2.023048 2.995681 6.857154 7.31791 6.051818 GNG2 0.958424642 0.043826549 0.013483498 14.52085298 3.819732 2.406905 5.018694 7.679787 8.385634 6.942983 HMGCS1 0.816660399 0.045162628 0.020920041 14.5130688 5.856559 4.750708 4.285996 10.641884 8.609988 6.618407 LOC643770 1.117096804 0.043485739 0.007676761 14.51004335 1.874444 2.023048 2.165421 6.498222 5.509998 5.882028 DPP8 1.104099415 0.04349335 0.008072133 14.51004335 1.874444 2.023048 2.165421 5.448591 6.205902 5.882028 LINC00488 1.05238887 0.043568903 0.009861177 14.51004335 1.874444 2.023048 2.165421 6.244586 5.165949 5.882028 RIMKLB 1.046530557 0.043577906 0.010072814 14.51004335 2.993831 2.023048 2.995681 6.664985 7.138979 5.882028 PARP11 0.983663847 0.043626235 0.012422593 14.51004335 3.839948 2.023048 2.165421 6.544171 7.174648 5.882028 C1GALT1 0.74650288 0.046800775 0.025893161 14.50130425 3.024504 2.023048 2.379345 7.177844 6.237456 3.676349 INPP5E 1.02264443 0.043577906 0.010933651 14.49692321 2.201691 3.360637 2.165421 6.183122 5.936219 7.218312 HES2 0.952232611 0.043900827 0.01379789 14.49692321 1.874444 3.360637 3.324375 6.063041 6.237456 7.218312 KCNJ8 0.786835204 0.045564387 0.022822729 14.47392391 5.779429 2.809601 2.165421 6.664985 6.551443 8.010706 IKZF5 1.02091215 0.043577906 0.011001701 14.46131325 1.874444 3.872014 3.764125 7.726141 7.107836 6.73963 MCM3 1.056412263 0.043540291 0.009709425 14.45597623 1.874444 3.32135 2.165421 5.728038 6.78473 6.924055 SFR1 1.04609294 0.043577906 0.010120449 14.45597623 1.874444 2.023048 3.764125 5.728038 7.406567 7.180104 LOC157273 0.899555091 0.044203301 0.016514461 14.45597623 1.874444 2.809601 3.935222 5.728038 7.870158 6.129407 E2F5 1.082808963 0.043516135 0.008856754 14.43926926 1.874444 2.023048 2.165421 6.067497 5.353925 5.874974 MBLAC2 1.077862218 0.043516135 0.009033685 14.43926926 1.874444 2.023048 2.165421 6.252746 5.306419 5.874974 SLC35B3 1.042809801 0.043577906 0.010235454 14.43926926 2.993831 2.023048 2.165421 5.891233 7.107836 5.874974 NGLY1 1.031533 0.043577906 0.010521266 14.43926926 3.350997 2.023048 2.995681 9.067384 6.640994 5.874974 HTATIP2 1.025522546 0.043577906 0.010749915 14.43926926 1.874444 2.023048 2.165421 5.026959 6.205902 5.874974 TDRD6 0.995138223 0.043626235 0.012027901 14.43926926 1.874444 2.023048 2.165421 6.664985 4.797798 5.874974 GAS1 0.974612548 0.043661316 0.012762164 14.43926926 3.819732 2.023048 2.995681 6.664985 8.385634 5.874974 ORC3 0.957906342 0.043835088 0.013521606 14.43926926 3.839948 2.023048 2.165421 7.243046 6.237456 5.874974 AURKAPS1 0.948191649 0.043900827 0.013980946 14.43926926 1.874444 2.023048 3.324375 7.25991 5.353925 5.874974 SERPINI1 0.853096372 0.044464174 0.018690711 14.43926926 1.874444 2.023048 2.165421 4.013424 6.189775 5.874974 CTSH 1.088511877 0.043516135 0.008655325 14.42331974 4.743564 4.413323 4.754917 8.779359 7.96603 8.593895 SMOC2 0.779294556 0.045829476 0.023356244 14.42331974 4.743564 4.389936 6.054038 6.651882 10.11666 8.593895 SNX2 0.981399472 0.043626235 0.012531473 14.41074015 4.263463 4.389936 2.379345 8.239009 7.89473 6.73963 SAMD8 1.118059859 0.043485739 0.007635931 14.40639168 5.056948 5.43468 4.508334 8.905585 8.842512 8.997112 UBA3 1.016826341 0.043581008 0.011184757 14.40593795 4.639409 3.32135 2.995681 8.488001 8.402869 6.455366 RPS24 1.020996618 0.043577906 0.010988091 14.38182469 8.313476 7.885522 8.616497 12.64513 12.15965 11.283573 DMTF1 1.067655726 0.043516135 0.009326301 14.34306104 2.993831 2.809601 2.165421 6.651882 7.440337 5.874974 EEF1G 1.107502832 0.043485739 0.007982987 14.33573698 9.127293 9.647142 9.369586 13.488686 12.910395 13.21983 LOC256880 1.097410022 0.04349335 0.0082967 14.33254145 4.309025 3.872014 4.508334 8.190235 7.713236 8.25089 ZBTB38 0.960462082 0.043778104 0.013357605 14.32134049 4.743564 2.809601 2.995681 7.243046 8.119857 6.649696 ZDHHC2 0.902605957 0.044190907 0.016317115 14.31879496 3.839948 2.406905 2.165421 7.679787 6.319269 5.426231 CR1 0.926698613 0.044037172 0.014997618 14.29740298 4.743564 2.406905 3.324375 6.244586 7.56803 8.053616 LRPPRC 0.997623938 0.043626235 0.011924464 14.29329005 4.815804 3.872014 3.90836 8.65307 8.314558 7.033813 LOC644961 1.069548309 0.043516135 0.009278666 14.2860105 3.839948 4.351315 4.285996 8.122528 7.31791 10.161929 C1QTNF9 0.805768824 0.045315307 0.021657707 14.27710635 5.304463 4.80797 5.018694 8.854326 9.266358 6.73963 C1orf50 1.102002758 0.04349335 0.008146989 14.26785693 1.874444 2.023048 2.165421 6.244586 5.857745 5.446557 CDC14A 1.048785385 0.043577906 0.009977543 14.26785693 1.874444 2.023048 2.165421 7.33564 5.857745 5.106393 TBCK 1.044737712 0.043577906 0.010181014 14.26785693 1.874444 2.023048 2.165421 6.857154 5.857745 5.091834 PDSS2 1.019411027 0.043577906 0.011069752 14.26785693 1.874444 2.023048 2.379345 6.664985 5.857745 5.091834 EREG 0.990539027 0.043626235 0.012170806 14.26785693 2.201691 2.023048 3.324375 7.177844 5.857745 5.882028 PRPH 0.989756962 0.043626235 0.012184416 14.26785693 1.874444 2.023048 2.165421 4.718672 5.857745 7.352555 FAM82A1 0.983404192 0.043626235 0.012449813 14.26785693 1.874444 2.023048 2.165421 6.252746 5.857745 4.790662 ESRRG 0.983169318 0.043626235 0.012470228 14.26785693 1.874444 2.023048 2.165421 6.244586 5.857745 4.790662 ANG 0.975676969 0.043661316 0.012714529 14.26785693 1.874444 2.023048 2.165421 8.433162 5.857745 4.562324 OMA1 0.944294196 0.043921714 0.014163321 14.26785693 1.874444 2.023048 2.165421 6.811341 5.857745 4.476242 HARS2 0.851463723 0.044490827 0.018793467 14.26785693 1.874444 2.023048 2.165421 7.897963 5.857745 3.676349 CKAP2 0.842228435 0.044657496 0.019307928 14.26785693 1.874444 2.023048 2.165421 7.748771 5.857745 3.630092 LOC221442 0.793585031 0.04542938 0.022440286 14.26785693 1.874444 2.023048 2.165421 6.183122 5.857745 3.630092 NOXA1 0.742666896 0.046946487 0.026169445 14.26785693 1.874444 2.023048 2.165421 7.42265 5.857745 2.921909 C8orf76 0.720622928 0.047703746 0.027855733 14.26785693 1.874444 2.023048 2.379345 7.25991 5.857745 2.921909 APBB1IP 0.686783046 0.04920934 0.030940456 14.26785693 1.874444 2.023048 2.379345 6.395481 5.857745 2.921909 TMEM111 1.059624928 0.043540291 0.009559714 14.23522131 3.024504 2.809601 2.379345 7.726141 6.640994 5.900694 KIAA0146 0.89273251 0.044203301 0.016876489 14.23522131 2.993831 2.809601 2.165421 8.628872 6.640994 4.562324 SLC4A1AP 1.143834603 0.043453389 0.006998979 14.23010699 1.874444 2.023048 2.165421 5.705318 5.936219 5.874974 KLLN 1.140594156 0.043453389 0.00713508 14.23010699 1.874444 2.023048 2.165421 5.705318 5.857745 5.900694 LOC139201 1.121744558 0.043480953 0.007542021 14.23010699 1.874444 2.023048 2.379345 5.705318 5.936219 6.195186 NSUN6 1.055981561 0.043540291 0.009736645 14.23010699 1.874444 2.023048 2.995681 5.705318 6.774676 6.129407 FLJ43663 1.057027623 0.043540291 0.0096754 14.22903071 1.874444 3.360637 3.764125 7.394225 7.191402 6.618407 MKL2 0.901228005 0.044203301 0.016400817 14.22691204 3.819732 2.406905 3.90836 8.591796 6.237456 6.455366 ZFYVE9 0.99590569 0.043626235 0.012000681 14.21268621 3.350997 2.023048 2.165421 5.320955 6.794431 7.180104 TMSB4X 1.043907148 0.043577906 0.010201429 14.21237819 8.996009 8.644729 9.426087 12.513364 13.255163 12.475083 INSIG1 0.981084043 0.043626235 0.012538278 14.20980575 5.856559 4.80797 6.450701 10.279516 9.847551 8.564524 RRM2B 0.900310527 0.044203301 0.016441647 14.15903323 3.350997 2.023048 3.935222 7.897963 7.174648 5.446557 PABPC1 1.123186538 0.043453389 0.007482137 14.12956085 8.313476 8.299167 8.291057 12.838225 12.119812 11.833387 ITGB1BP1 0.802070401 0.04534393 0.021887036 14.12606251 2.993831 2.023048 5.217616 6.814118 7.53715 6.129407 ECM2 0.709198475 0.04824159 0.028872406 14.11803152 3.024504 3.360637 6.564874 7.074163 8.055928 7.180104 RRAD 1.011008732 0.043581008 0.011409323 14.10466763 5.056948 2.809601 4.724406 8.875048 7.713236 8.155622 DAPK2 0.946377089 0.043900827 0.014083021 14.10005355 2.993831 3.32135 4.508334 8.665019 7.138979 6.455366 LOC220906 1.140709197 0.043453389 0.007128275 14.08829911 4.682076 4.911517 4.724406 8.540832 9.064538 8.456743 SHQ1 0.978733216 0.043661316 0.012592038 14.08258955 1.874444 2.023048 2.379345 4.802615 6.189775 6.195186 CXCL3 0.749465998 0.046704093 0.025647499 14.07352354 4.263463 4.413323 6.670675 10.485586 9.962448 5.874974 AAA1 1.018919503 0.043577906 0.011096972 14.07052669 2.201691 2.406905 3.324375 5.705318 7.138979 6.618407 BSN-AS2 0.8385434 0.044732882 0.01958149 14.06473587 3.350997 3.360637 4.285996 5.728038 7.174648 8.155622 DSP 0.793880673 0.04542938 0.022426676 14.06009743 4.682076 7.631788 3.935222 10.548217 8.951948 7.748756 PDLIM3 1.050566712 0.043568903 0.009915618 14.02742823 4.743564 4.413323 4.754917 8.553743 7.740604 9.040427 MAP3K9 0.814221447 0.045212649 0.021144607 14.01408571 1.874444 2.809601 4.754917 6.063041 6.78473 6.618407 PTPN18 0.973814798 0.043681142 0.012804355 14.00766253 3.819732 4.736586 3.764125 9.154721 7.627877 7.033813 SBF2 0.970981042 0.043709154 0.012935692 13.99444021 4.309025 3.360637 2.165421 7.167419 7.713236 6.455366 NDUFS3 1.110983164 0.043485739 0.007874107 13.99129137 5.335413 4.413323 5.225216 9.111713 9.031674 8.66481 EHF 0.7549496 0.046508764 0.025275264 13.97511937 5.304463 6.670655 2.379345 10.475444 9.188984 6.106561 IMPA1 1.04772849 0.043577906 0.010025179 13.96656846 3.839948 2.023048 3.764125 7.607339 7.56803 6.69026 SLC22A5 0.993512731 0.043626235 0.012055121 13.96532733 3.350997 3.360637 2.379345 6.183122 7.174648 6.649696 PHYHD1 0.949445559 0.043900827 0.013912896 13.94617002 4.209882 3.360637 5.723602 8.553743 8.011679 7.96648 FAM49A 1.035537679 0.043577906 0.01040558 13.91912931 1.874444 2.406905 3.324375 6.954147 6.205902 6.051818 RPS6KA6 1.008301876 0.043581008 0.011470568 13.91912931 1.874444 2.406905 2.995681 7.25991 6.205902 5.446557 LOC100506207 0.926981767 0.044037172 0.014977203 13.91912931 1.874444 2.406905 3.764125 6.283686 6.205902 6.106561 MGMT 0.99141493 0.043626235 0.012150391 13.91361075 3.024504 2.809601 2.165421 5.448591 6.608026 7.395512 KIAA1407 0.787533324 0.045564387 0.022788704 13.91361075 2.201691 2.809601 5.389265 6.283686 6.608026 7.640338 PRMT5 1.017221766 0.043581008 0.011164342 13.90908257 5.753024 4.736586 4.508334 9.146221 8.502167 8.534542 PATE4 1.097913468 0.04349335 0.008262674 13.9067527 5.491121 5.195784 5.571599 8.993498 9.722706 9.040427 GNAI3 0.979191052 0.043656588 0.01258115 13.87348654 5.263699 4.830496 4.285996 9.276547 8.624754 7.611911 ZNF621 1.033115094 0.043577906 0.01046002 13.86397202 4.209882 3.872014 4.944468 8.051486 8.737737 7.640338 CCP110 0.902824777 0.044190907 0.0162967 13.85625192 4.263463 2.023048 4.754917 6.252746 8.055928 8.374509 USPL1 1.024608342 0.043577906 0.010817965 13.84140973 4.309025 3.32135 3.935222 7.726141 8.436733 6.931222 GTF2H2B 1.087919069 0.043516135 0.008696155 13.84121555 2.993831 2.406905 2.995681 7.531061 6.78473 6.106561 KIAA0586 0.913355773 0.044110923 0.015693773 13.82489366 4.815804 2.023048 3.764125 7.70315 6.613395 7.553321 WDR48 0.996653353 0.043626235 0.01197346 13.82347586 4.263463 3.360637 2.995681 8.122528 6.78473 7.033813 ARHGAP15 0.884482085 0.044203301 0.017243961 13.81541049 1.874444 3.32135 4.754917 7.109557 6.189775 7.722406 GALNT11 1.096665775 0.04349335 0.00833753 13.80562198 4.263463 4.351315 3.935222 8.222933 7.870158 7.722406 LARP4 0.958079125 0.043835088 0.013507996 13.79894094 3.839948 3.32135 2.165421 7.109557 7.107836 6.106561 SNAPC1 0.998065909 0.043626235 0.011910854 13.79697838 8.388231 7.08238 8.12722 10.880921 11.885468 12.174512 EIF3H 1.052757427 0.043568903 0.009840762 13.78898303 6.648293 7.26179 7.462086 11.610972 10.859474 10.433737 CTTNBP2NL 1.023614469 0.043577906 0.010879211 13.78647971 3.024504 2.406905 3.324375 7.109557 6.373501 6.32627 RBM3 1.111044175 0.043485739 0.007867302 13.77507509 6.736762 6.537655 5.018694 10.321643 10.202833 10.345825 DDX60L 0.992112054 0.043626235 0.012129976 13.77004465 1.874444 2.406905 3.324375 5.448591 7.107836 6.587378 EPS8 1.038325377 0.043577906 0.010357945 13.74532532 6.820119 6.03611 6.054038 9.663593 9.834907 11.049199 DNAJC12 0.867949044 0.044335719 0.017983668 13.745096 2.993831 4.413323 2.379345 9.4454 6.774676 5.426231 SGTB 1.013718375 0.043581008 0.011314052 13.7289854 4.209882 3.360637 3.764125 7.835902 7.989035 6.73963 NAV3 0.893739147 0.044203301 0.016835658 13.7274795 2.201691 2.023048 2.995681 6.063041 6.774676 4.790662 SART3 0.962279841 0.043778104 0.013269139 13.72644992 3.350997 4.389936 4.754917 8.190235 8.533804 6.942983 PIGR 0.941813219 0.043921714 0.014306227 13.69663959 4.743564 6.983552 4.754917 10.653925 9.188984 8.519314 PPM1B 1.075272138 0.043516135 0.009088125 13.68950702 8.947392 8.203594 8.75928 11.971229 12.722391 12.710353 SF3B14 0.997377571 0.043626235 0.011931269 13.6646932 4.639409 5.487673 5.018694 9.789006 8.791075 7.96648 KIF14 0.935197228 0.044003812 0.014575706 13.6497119 1.874444 2.406905 2.165421 7.144104 5.936219 4.562324 CCDC58 0.91218818 0.044142622 0.015761143 13.6497119 1.874444 3.770995 2.165421 6.544171 5.936219 5.882028 MTOR 0.829413633 0.044930476 0.020167404 13.6497119 1.874444 2.809601 2.165421 6.960054 5.936219 4.146207 GPN1 0.825741854 0.044949653 0.020383124 13.6497119 2.993831 2.023048 2.165421 7.856887 5.936219 4.146204 MON1B 0.771851268 0.046057921 0.023944199 13.6497119 6.099991 2.809601 2.165421 7.835902 5.936219 7.988762 ELF5 0.731102124 0.047384624 0.027039809 13.6497119 1.874444 2.406905 2.165421 7.814607 5.936219 2.921909 HAUS3 1.114454922 0.043485739 0.007765226 13.63320281 5.316227 5.487673 5.225216 9.08528 8.892178 9.49312 ZC3H11A 1.019394149 0.043577906 0.011076557 13.63173987 6.736762 4.911517 5.018694 10.50566 10.074256 8.534542 DECR1 1.112053053 0.043485739 0.007833277 13.62825669 4.309025 3.32135 4.285996 7.771052 8.077554 7.96648 MGP 0.775047768 0.045974332 0.023755699 13.62804816 8.341965 10.719181 9.197307 15.205994 12.965814 10.904315 SMARCA5 1.057535333 0.043540291 0.00964818 13.62258063 4.682076 4.351315 3.935222 7.70315 8.518072 8.010706 WDR92 0.921537088 0.044110923 0.015275264 13.58215181 3.024504 3.872014 4.449894 6.252746 7.819723 8.213534 FAM8A1 0.992323431 0.043626235 0.012123171 13.56369603 4.743564 4.351315 4.724406 8.665019 8.486085 7.46072 PDHX 0.933782907 0.044025007 0.014641715 13.55311089 4.309025 3.872014 2.165421 8.069577 6.78473 6.73963 EGFL6 1.11998904 0.043485739 0.007601905 13.54548907 1.874444 2.023048 2.165421 5.743334 6.613395 5.634184 GLCCI1 0.919809554 0.044110923 0.015349439 13.54548907 1.874444 2.809601 4.285996 7.607339 7.187136 5.634184 CRIPAK 0.895084284 0.044203301 0.016753998 13.54548907 1.874444 4.351315 2.379345 7.167419 6.861783 5.634184 AGK 0.883590092 0.044229452 0.01729772 13.54548907 1.874444 3.770995 2.165421 6.067497 6.319269 5.634184 LOC100288181 0.778542863 0.045844227 0.023430419 13.54548907 1.874444 2.023048 4.285996 5.891233 6.043524 5.634184 AVPR1A 0.827524069 0.044930476 0.02025723 13.53839483 1.874444 2.023048 3.764125 4.739845 5.920411 7.523109 STEAP2 0.928552837 0.044037172 0.014888738 13.53481323 4.743564 4.413323 2.995681 7.037879 8.502167 7.523109 ANKRD6 0.998330914 0.043626235 0.011904049 13.53211211 3.839948 2.809601 2.165421 5.705318 7.598264 7.553321 TLK1 0.987114554 0.043626235 0.012300102 13.51827682 3.350997 2.023048 2.379345 5.579836 7.107836 6.385515 FHDC1 1.095417327 0.04349335 0.00839197 13.50702375 5.658609 5.195784 5.544653 8.905585 9.409671 9.414247 FANCL 1.031298948 0.043577906 0.010534876 13.50095651 1.874444 2.023048 2.165421 5.891233 5.920411 5.106393 ACSL6 0.995871176 0.043626235 0.012007486 13.50095651 1.874444 2.809601 2.165421 5.320955 5.920411 6.722123 ANO9 0.96057342 0.043778104 0.0133508 13.50095651 1.874444 3.360637 2.165421 6.814118 5.920411 5.634184 ERV3-1 0.947611968 0.043900827 0.014028581 13.50095651 2.993831 2.023048 2.165421 7.556937 5.920411 5.106393 DIRC2 0.667139886 0.050335207 0.033083362 13.50095651 2.201691 2.023048 2.165421 6.063041 5.920411 2.921909 UGP2 0.944249416 0.043921714 0.014170126 13.47046923 5.658609 4.736586 4.508334 9.410337 8.829823 7.611911 CMTM7 0.804113829 0.045327183 0.021778156 13.45545007 1.874444 4.389936 3.935222 9.094145 7.68534 4.790662 BOD1 1.001742819 0.043588662 0.011796529 13.45492599 3.350997 2.809601 2.379345 7.582358 6.189775 6.129407 TAPT1 0.87954746 0.044278935 0.017456278 13.45492599 3.839948 4.830496 2.379345 8.79031 7.414086 6.129407 BOLA3-AS1 1.002821442 0.043588662 0.011755699 13.4523652 3.350997 4.389936 3.324375 7.074163 7.174648 7.774634 TRIP12 1.074870198 0.043516135 0.00910854 13.44966268 4.309025 4.736586 5.018694 8.711848 8.486085 8.135789 BRD7 0.975155564 0.043661316 0.012741749 13.44068357 3.819732 3.360637 3.90836 6.498222 7.656894 7.582913 TLR7 0.986328177 0.043626235 0.012320517 13.43228908 4.263463 4.413323 4.944468 7.504712 8.160956 8.705744 CLCN6 1.049345748 0.043568903 0.009942838 13.42865379 4.263463 2.406905 3.764125 7.109557 7.414086 8.010706 MEIS1 0.830335198 0.044867325 0.020073494 13.41522476 2.993831 2.023048 3.935222 4.894482 7.989035 6.73963 IRF2 0.867011268 0.044369384 0.018053079 13.39803104 4.743564 4.736586 2.995681 8.811966 7.505595 6.73963 MRPS18B 0.98608769 0.043626235 0.012327322 13.38300836 6.008206 5.809601 4.944468 8.447068 9.708913 9.750536 AUH 1.007218577 0.043588662 0.011571963 13.37847188 1.874444 2.809601 3.90836 7.450526 6.551443 6.385515 DPH5 1.059697576 0.043540291 0.009546104 13.37793922 2.201691 3.872014 3.324375 7.144104 7.066159 7.020304 TUBA1C 0.927936308 0.044037172 0.014929568 13.33791063 5.658609 6.638536 4.754917 9.396069 8.751258 9.555312 LEPR 0.911732464 0.044142622 0.015795168 13.33191166 9.227402 9.276362 9.869299 11.967616 13.740642 13.013174 RYR2 1.05630484 0.043540291 0.00971623 13.3177051 1.874444 2.023048 2.165421 5.252045 5.857745 5.900694 CWC27 0.955907864 0.043840967 0.013641375 13.3177051 3.350997 3.360637 2.165421 7.177844 6.613395 5.900694 LOC389765 0.952497365 0.043882243 0.013778156 13.3177051 2.201691 2.023048 2.165421 6.067497 4.797798 5.900694 XXYLT1 0.944859702 0.043921714 0.014142906 13.3177051 1.874444 2.809601 2.165421 5.026959 6.551443 5.900694 C16or74 0.907503097 0.044173537 0.016022457 13.3177051 2.201691 2.023048 2.165421 6.067497 4.539173 5.900694 MDM1 0.872420424 0.044299467 0.017765226 13.3177051 3.024504 2.023048 2.165421 4.718672 6.861783 5.900694 DNAJC19 0.781046631 0.045805247 0.023277305 13.3177051 5.328526 3.32135 2.165421 7.835902 7.187136 5.900694 GPR183 1.012672647 0.043581008 0.011368493 13.3108308 2.201691 2.023048 2.379345 8.105092 5.936219 5.106393 TINF2 0.939211476 0.043986717 0.014431439 13.30547426 4.263463 3.360637 2.379345 6.339437 7.094585 7.46072 NUCB2 0.860242611 0.044379352 0.018394692 13.25189934 6.48761 3.770995 3.764125 9.111713 8.385634 7.492252 IAPP 1.025506518 0.043577906 0.01075672 13.23065208 1.874444 2.023048 2.165421 5.891233 5.857745 5.091834 RPE 1.008255147 0.043581008 0.011477373 13.23065208 1.874444 2.406905 2.165421 5.891233 6.608026 5.106393 RCBTB2 0.939993697 0.043921714 0.014367472 13.23065208 2.201691 2.023048 2.165421 5.891233 7.174648 4.562324 MGAT2 0.909912382 0.044159136 0.015906091 13.23065208 1.874444 2.809601 2.165421 5.891233 6.613395 4.790662 SKIV2L 0.907950146 0.044173537 0.016002042 13.23065208 1.874444 2.809601 2.165421 5.891233 6.551443 4.790662 AASDH 0.892343309 0.044203301 0.016883294 13.23065208 1.874444 2.406905 2.165421 5.891233 6.205902 4.476242 ZNF860 0.686280596 0.049293152 0.031014631 13.23065208 1.874444 2.406905 2.165421 5.891233 6.640994 2.921909 CAB39L 0.952083378 0.043900827 0.01381082 13.20033324 2.993831 2.406905 3.764125 7.607339 6.373501 6.129407 DNMT3A 0.760899973 0.046345577 0.024798911 13.20033324 4.639409 2.406905 2.165421 6.063041 6.189775 6.129407 MBNL2 0.834966314 0.044793607 0.019722355 13.1876666 5.328526 5.789702 6.175931 9.565008 9.897049 7.722406 PARP4 1.117161292 0.043485739 0.007669956 13.18007422 2.201691 2.023048 2.165421 5.743334 7.53715 5.874974 ZNF300 1.075239313 0.043516135 0.00909493 13.18007422 1.874444 2.023048 2.165421 5.743334 5.353925 6.722123 LOC100505989 1.052826099 0.043568903 0.009833957 13.18007422 2.993831 2.023048 2.165421 5.743334 6.373501 6.455366 MZT1 1.035730746 0.043577906 0.010385165 13.18007422 1.874444 2.023048 2.165421 5.743334 6.861783 5.106393 LOC100130000 0.973497609 0.043681142 0.01282477 13.18007422 3.350997 2.023048 2.165421 5.743334 6.189775 6.385515 CLSTN2 0.942030873 0.043921714 0.014292617 13.18007422 1.874444 2.023048 2.165421 5.743334 4.539173 6.649696 SIX4 0.935684973 0.043994974 0.014534876 13.18007422 3.024504 2.023048 3.935222 5.743334 7.505595 6.924055 GIMAP1 0.772583258 0.046036363 0.023882953 13.18007422 1.874444 2.023048 2.165421 5.743334 3.571326 6.051818 BOD1L 1.052687501 0.043568903 0.009847567 13.16714224 4.682076 4.830496 4.285996 8.460842 8.549366 7.849596 GTF2H5 1.116087126 0.043485739 0.007703981 13.15881989 5.335413 3.32135 5.389265 9.012327 9.107223 9.018932 PRSS35 1.051079108 0.043568903 0.009902007 13.14650042 1.874444 2.406905 2.165421 6.960054 5.353925 5.882028 NUP35 1.046288019 0.043577906 0.010113644 13.14650042 2.201691 2.809601 2.165421 6.067497 6.043524 5.882028 UGT2B10 1.038587589 0.043577906 0.010344335 13.14650042 2.201691 2.023048 2.165421 5.252045 6.205902 5.882028 ARHGEF37 0.918348441 0.044110923 0.015410684 13.14650042 2.201691 2.023048 2.165421 6.067497 4.608763 5.882028 BRMS1L 0.905774021 0.044173537 0.016117727 13.14650042 2.993831 2.023048 2.165421 4.894482 7.094585 5.882028 C9orf46 0.878595308 0.044280042 0.017514801 13.14650042 4.209882 3.872014 2.165421 9.16317 6.78473 5.882028 LIN7C 0.700514603 0.04869904 0.029825791 13.14650042 6.227577 2.809601 2.165421 7.748771 7.25505 5.882028 FAM190A 1.044609719 0.043577906 0.010187819 13.13301274 3.024504 2.023048 2.165421 5.728038 6.205902 6.73963 CMYA5 1.013627102 0.043581008 0.011327662 13.13301274 3.024504 3.32135 2.165421 6.067497 6.794431 6.73963 SLC35E3 1.015724372 0.043581008 0.011211977 13.09663538 4.639409 3.360637 4.449894 7.477873 8.350533 7.897492 FLNB 0.960306262 0.043778104 0.01336441 13.09607079 3.819732 5.195784 4.449894 9.466036 8.160956 7.291822 METTL21D 0.956439729 0.043840967 0.013600544 13.08955464 3.024504 3.872014 2.379345 7.582358 6.608026 6.106561 HCN1 0.935154639 0.044003812 0.014582511 13.08237714 2.201691 2.023048 2.165421 4.739845 5.936219 5.874974 SENP2 0.868608189 0.044335719 0.017936033 13.08237714 4.639409 2.809601 2.165421 7.210813 7.191402 5.874974 SEMA3C 0.764909652 0.046181862 0.024498809 13.08237714 2.201691 4.750708 2.165421 6.067497 6.613395 5.874974 FLI1 1.041810741 0.043577906 0.010255869 13.08134273 3.024504 2.406905 3.324375 6.283686 6.613395 7.033813 TRPM8 0.863251995 0.044377262 0.018232732 13.08134273 1.874444 4.80797 3.324375 6.244586 7.473335 7.033813 BCKDHB 1.046439605 0.043577906 0.010086424 13.07927039 4.309025 4.413323 3.764125 8.239009 7.473335 7.849596 HSPA7 0.695394114 0.048858998 0.030266757 13.0513108 5.335413 6.139057 9.749619 9.29204 12.218027 9.84518 TCTEX1D2 0.983058134 0.043626235 0.012483838 13.05101308 1.874444 3.360637 2.165421 6.252746 6.774676 5.580533 ARNTL 0.946802221 0.043900827 0.014048996 13.05101308 1.874444 2.406905 3.324375 6.396698 6.189775 5.580533 ILKAP 1.070054726 0.043516135 0.009258251 13.04470248 1.874444 2.023048 2.379345 5.579836 7.187136 5.634184 FAM58A 1.007836257 0.043581008 0.011531814 13.04470248 1.874444 2.023048 2.995681 5.579836 6.613395 5.874974 LEPREL1 0.880598153 0.044278935 0.017415447 13.04470248 1.874444 4.911517 2.995681 5.579836 7.870158 7.988762 ISCA2 1.086064959 0.043516135 0.008736985 13.04106563 1.874444 2.023048 2.165421 5.728038 7.174648 5.446557 CCDC126 1.084803539 0.043516135 0.008771011 13.04106563 1.874444 2.023048 2.165421 5.728038 6.189775 5.426231 BDNF-AS1 1.073452982 0.043516135 0.009142565 13.04106563 1.874444 2.023048 2.165421 5.728038 5.353925 6.73963 SENP8 1.065863922 0.043516135 0.009373937 13.04106563 1.874444 2.023048 2.165421 5.728038 5.306419 6.722123 FMO4 1.032779289 0.043577906 0.010487241 13.04106563 1.874444 2.023048 2.165421 5.728038 7.174648 5.091834 LINC00547 1.030678725 0.043577906 0.010555291 13.04106563 3.024504 2.023048 2.165421 5.728038 6.613395 6.106561 FIGNL1 1.018897029 0.043577906 0.011103777 13.04106563 1.874444 2.023048 2.165421 5.728038 5.920411 5.091834 C14orf126 0.976429387 0.043661316 0.012673699 13.04106563 2.993831 2.023048 2.165421 5.728038 5.936219 5.882028 LOC100505648 0.938608641 0.043986717 0.014438244 13.04106563 1.874444 2.023048 2.165421 5.728038 4.608763 6.106561 TMEM200A 0.893808062 0.044203301 0.016828853 13.04106563 1.874444 2.023048 2.995681 5.728038 4.797798 6.931222 CHEK2P2 0.876769665 0.044280042 0.017582851 13.04106563 1.874444 2.023048 2.165421 5.728038 6.551443 4.146207 COQ10A 0.736220688 0.047233845 0.026663491 13.04106563 4.743564 2.023048 2.379345 5.728038 6.373501 6.106561 ZNF485 0.999751667 0.043626235 0.011870024 13.02812046 4.682076 3.360637 5.018694 7.556937 8.385634 8.593895 ANKRD36BP1 0.948516997 0.043900827 0.013967336 13.0175637 5.328526 5.43468 7.003286 9.030914 10.173004 9.555312 PRSS23 0.880794027 0.044278935 0.017408642 13.0175637 5.328526 2.809601 3.90836 9.030914 8.314558 6.195186 MCCC1 0.888695309 0.044203301 0.01706703 13.01713567 5.491121 3.770995 2.995681 8.087444 7.473335 7.36177 FILIP1L 1.003769199 0.043588662 0.011721674 13.00581703 5.263699 3.32135 4.449894 8.964784 7.740604 8.074602 CHRNA5 0.973688171 0.043681142 0.01281116 12.99331557 6.227577 5.809601 5.974145 8.768324 9.673843 10.524247 ZFYVE19 1.005168799 0.043588662 0.011646819 12.98706672 2.201691 3.360637 2.995681 7.582358 6.608026 5.900694 GPR75-ASB3 0.939506889 0.043955231 0.014406261 12.98706672 2.201691 2.406905 2.165421 4.802615 6.861783 5.900694 NIPSNAP3A 0.925740635 0.04407613 0.01509493 12.98706672 2.201691 3.32135 2.995681 7.037879 5.936219 5.900694 HPSE 0.905532708 0.044173537 0.016144947 12.98706672 2.201691 2.809601 2.165421 4.894482 6.640994 5.900694 DRAM2 0.992702757 0.043626235 0.012102756 12.98661625 4.743564 3.32135 3.324375 8.41912 7.440337 7.020304 NUDT5 0.95948838 0.043826549 0.013429058 12.98661625 4.682076 3.32135 2.165421 7.995811 6.794431 7.020304 SNHG6 1.012942415 0.043581008 0.011354883 12.97747945 7.198002 7.152299 7.628916 11.326854 11.018888 10.396714 CPSF6 0.901304404 0.044203301 0.016387207 12.97460589 3.024504 3.770995 5.389265 8.301578 8.2398 6.722123 IAH1 0.895650913 0.044203301 0.016713168 12.97460589 3.024504 4.351315 2.165421 6.183122 7.191402 6.722123 LONRF1 0.798796476 0.045355733 0.022082341 12.97315853 6.143785 5.661685 6.175931 7.556987 9.841243 10.489503 RAB3B 0.929557121 0.044037172 0.014841102 12.9639101 2.993831 2.023048 2.165421 4.802615 6.608026 6.69026 NCSTN 0.876014478 0.044285705 0.01762096 12.94729481 4.263463 2.023048 2.995681 5.579836 8.011679 6.69026 RTCD1 0.823032559 0.045019115 0.020541681 12.94729481 4.639409 4.413323 2.995681 8.40494 6.794431 6.69026 PHKG2 0.956949091 0.043840967 0.013586934 12.93451072 3.819732 4.351315 5.018694 8.711848 7.68534 7.523109 ARHGAP25 0.962375098 0.043778104 0.013262334 12.92707283 1.874444 2.023048 2.165421 5.743334 5.857745 4.790662 RIC3 0.915056776 0.044110923 0.015584893 12.92707283 1.874444 3.360637 2.165421 6.067497 5.857745 5.634184 PKIB 0.743055806 0.046915454 0.02612181 12.92707283 1.874444 2.809601 2.165421 9.657624 5.857745 2.921909 TMEM42 0.705574031 0.048360255 0.029273903 12.92707283 3.350997 2.023048 2.165421 7.177844 5.857745 3.676349 FAM120B 0.917067225 0.044110923 0.015455597 12.91622318 3.839948 3.32135 2.165421 7.531061 7.138979 5.634184 AHI1 1.036240011 0.043577906 0.01037836 12.91467332 5.779429 5.809601 5.974145 9.030914 9.500541 9.757043 GPR82 0.898393736 0.044203301 0.016566179 12.90217497 2.201691 2.023048 2.165421 5.891233 4.539173 5.882028 RPGR 0.851242427 0.044490827 0.018800272 12.89393432 4.743564 2.809601 2.379345 6.498222 7.174648 6.455366 C15orf40 0.938171393 0.043986717 0.014458659 12.88497394 5.744513 4.389936 5.544653 9.727662 8.077554 8.758577 PPFIBP1 1.095498972 0.04349335 0.00837836 12.87109469 5.263699 5.487673 5.389265 8.843852 9.075328 9.50208 ZNF140 0.983580619 0.043626235 0.012436203 12.86930913 3.819732 3.360637 2.379345 6.550689 7.505595 6.587378 PPP1R2 1.00176233 0.043588662 0.011789724 12.86684943 4.815804 4.736586 3.764125 8.501391 7.656894 8.11568 TPCN1 1.024569533 0.043577906 0.01082477 12.84075276 4.309025 4.351315 4.724406 8.501391 8.033973 7.640338 CD28 1.095383167 0.04349335 0.00840558 12.83730384 1.874444 2.023048 2.165421 5.705318 5.509998 6.69026 RNF212 1.085781213 0.043516135 0.00874379 12.83730384 1.874444 2.023048 2.165421 5.705318 6.608026 5.446557 ABCB6 1.070750359 0.043516135 0.009224226 12.83730384 1.874444 2.023048 2.165421 5.705318 5.353925 6.385515 VEGFC 1.064677912 0.043516135 0.009401157 12.83730384 1.874444 2.023048 2.165421 5.705318 5.317867 6.385515 CDYL 0.932063488 0.044025007 0.014723375 12.82873632 5.304463 3.872014 2.995681 7.477873 8.140553 7.553321 EHBP1 0.857716308 0.044387761 0.018475672 12.817417 3.024504 3.770995 4.285996 5.743334 7.96603 7.722406 CHRDL1 0.902567775 0.044190907 0.01632392 12.77680226 5.056948 3.32135 6.527811 8.40494 9.075328 8.732403 MTX3 0.924460444 0.044086036 0.015139843 12.77409406 4.639409 3.360637 3.935222 6.396698 8.314558 8.175185 WBSCR22 0.95996168 0.043802358 0.013406601 12.76390771 4.743564 4.736586 3.90836 7.582358 7.740604 8.519314 ANKRD44 1.014077323 0.043581008 0.011307247 12.75758124 2.201691 2.023048 2.995681 6.339437 5.857745 5.874974 CTH 0.989125746 0.043626235 0.012204832 12.75758124 2.201691 2.406905 3.324375 8.139755 5.936219 5.874974 ACPL2 0.919184342 0.044110923 0.015356244 12.75758124 2.201691 2.023048 3.324375 7.144104 5.306419 5.874974 MTHFD1 0.895336418 0.044203301 0.016726778 12.75758124 2.201691 4.389936 3.324375 7.835902 7.174648 5.874974 COX8A 1.032589058 0.043577906 0.010494046 12.75456761 7.218633 6.35207 6.670675 10.632786 10.025012 10.573 SLA 0.771698267 0.046066162 0.02395917 12.74220491 1.874444 3.360637 5.609945 7.631894 6.319269 7.03218 PRF1 0.841524278 0.044701668 0.019371895 12.72892144 3.350997 5.43468 5.596986 7.42265 8.119857 9.267025 GGCT 0.902290194 0.044190907 0.01635114 12.72278325 1.874444 3.770995 2.165421 7.074163 7.440337 4.790662 HYAL2 0.915002802 0.044110923 0.015598503 12.72247443 3.350997 2.023048 2.165421 5.095353 6.205902 7.020304 TSEN15 0.860416238 0.044379352 0.018381082 12.72244641 4.682076 2.023048 2.995681 6.664985 6.794431 6.587378 RPS18 1.067036784 0.043516135 0.009346717 12.71370293 10.48024 11.04134 10.756834 14.660003 14.518428 14.148553 ARID4A 1.006104008 0.043588662 0.011619599 12.70866207 4.309025 2.406905 3.90836 7.976765 7.31791 7.020304 HECTD1 0.994906277 0.043626235 0.012041511 12.69662826 5.056948 3.32135 4.724406 8.723321 8.140553 7.695565 BRMS1 0.956525242 0.043840967 0.013593739 12.69119225 3.024504 3.32135 2.165421 7.531061 5.509998 6.69026 CRAMP1L 1.004840221 0.043588662 0.011674039 12.64950863 5.744513 5.487673 5.225216 8.514658 9.148683 9.525135 AOX1 1.074716038 0.043516135 0.009115345 12.64585358 1.874444 2.406905 2.165421 6.067497 5.509998 6.051818 PSMA4 0.933581517 0.044025007 0.014655325 12.64150737 5.779429 5.661685 3.764125 9.33006 9.321782 7.873743 RNF6 0.829055687 0.044930476 0.020194624 12.62359827 2.993831 2.023048 2.165421 6.651882 6.608026 4.146207 LIMCH1 0.875488467 0.044285705 0.01766179 12.61868652 2.201691 3.770995 5.544653 7.995811 7.187136 7.428484 CCNDBP1 0.769300124 0.046082352 0.024102756 12.61868652 6.381847 3.770995 3.90836 7.748771 8.402869 7.428484 GOLGA8IP 1.056494403 0.043540291 0.009695815 12.61037063 8.971905 8.783406 9.203198 12.307705 12.991677 12.628444 ZFP90 0.885867603 0.044203301 0.01718952 12.60685291 3.819732 2.406905 3.90836 6.063041 6.78473 7.640338 PRPS2 0.913024725 0.044110923 0.015707383 12.60613267 2.201691 2.406905 2.165421 4.739845 5.857745 6.32627 DUSP19 0.948708747 0.043900827 0.013946921 12.58949229 8.485078 7.631788 8.685452 10.965483 12.139226 12.489807 OLA1 0.937081433 0.043994974 0.014487241 12.57340381 3.839948 5.362142 4.944468 10.048181 8.181074 7.492252 FAM214A 0.945422529 0.043921714 0.014122491 12.57216282 4.815804 4.750708 6.072169 9.506443 8.402869 8.472642 ENSA 1.03205867 0.043577906 0.010514461 12.56538264 6.227577 4.911517 5.592916 9.87896 9.09667 9.163078 LRP12 0.87957494 0.044278935 0.017449473 12.55301339 1.874444 2.023048 3.764125 6.067497 7.414086 5.091834 MLH3 0.801599728 0.045343936 0.021904729 12.54436002 3.839948 2.809601 4.449894 5.252045 8.098861 8.053616 FAM200B 0.967250065 0.043778104 0.013099013 12.5365444 4.743564 5.195784 3.764125 8.843852 8.314558 7.553321 RUNX2 0.670323386 0.050073072 0.032698197 12.52868649 2.993831 2.023048 5.596986 6.814118 6.640994 5.874974 EML4 0.952658484 0.043882243 0.013771351 12.52426057 5.328526 4.750708 6.012527 9.909415 8.97518 8.194487 LOC100131067 1.024626663 0.043577906 0.01081116 12.51654746 3.024504 2.809601 2.165421 5.743334 7.406567 6.455366 NAAA 0.983954015 0.043626235 0.012402178 12.50916052 3.350997 2.406905 2.995681 6.339437 7.187136 6.051818 SEC22C 1.037677767 0.043577906 0.01036475 12.49548073 5.056948 4.80797 4.285996 8.700282 8.696398 7.897492 GCFC2 0.804246691 0.045327183 0.021750936 12.49337873 4.639409 3.770995 2.379345 8.301578 7.414086 5.446557 C1orf63 1.065498536 0.043516135 0.009380742 12.48621817 6.707871 6.732825 7.156853 10.420113 10.779249 10.350135 LINC00260 0.799943579 0.045343942 0.022044913 12.45543243 5.335413 3.32135 5.609945 6.960054 7.767462 10.191053 GSDMD 0.907617969 0.044173537 0.016015652 12.45155452 4.639409 6.060401 3.764125 7.897963 8.277663 9.172843 SLC25A30 0.973254286 0.043681142 0.01283838 12.43744748 3.024504 2.406905 2.165421 7.274575 6.043524 5.446557 FUNDC1 0.849557077 0.044521554 0.018904389 12.43744748 2.993831 2.406905 2.165421 7.30543 6.043524 4.562324 PDZRN3 0.814410562 0.045212649 0.021137802 12.429554 4.963444 3.32135 4.754917 8.39062 8.609988 6.195186 NADSYN1 1.080299071 0.043516135 0.00895883 12.42827745 1.874444 2.023048 2.165421 7.679787 5.509998 5.634184 ZC3H12B 1.078996504 0.043516135 0.00899966 12.42827745 1.874444 2.023048 2.165421 5.891233 5.509998 5.580533 TTC9C 1.072643204 0.043516135 0.009190201 12.42827745 1.874444 2.023048 2.165421 7.835902 5.509998 5.580533 ZC4H2 1.055026165 0.043540291 0.009763865 12.42827745 1.874444 2.406905 2.165421 5.891233 5.509998 5.900694 NRXN3 1.053820818 0.043568903 0.009806737 12.42827745 1.874444 2.406905 2.165421 5.891233 5.509998 5.882028 WRN 0.975824963 0.043661316 0.012707724 12.42827745 1.874444 3.32135 2.379345 6.544171 5.509998 6.587378 PRKCB 0.973545341 0.043681142 0.012817965 12.42827745 1.874444 2.023048 2.995681 5.891233 5.509998 6.051818 MYBL1 0.97173629 0.043681142 0.012913236 12.42827745 1.874444 2.406905 3.324375 6.664985 5.509998 6.455366 ZNF711 0.800604577 0.045343936 0.02194556 12.42590411 4.209882 2.023048 3.935222 6.183122 7.845161 6.051818 WDR17 0.995350607 0.043626235 0.012021096 12.40464627 3.024504 3.360637 3.935222 6.396698 7.56803 7.327219 ISG15 0.852817719 0.044464174 0.018711126 12.39243525 4.682076 2.023048 3.764125 7.897963 5.936219 7.395512 SLC16A4 1.040741441 0.043577906 0.010283089 12.33932494 3.024504 2.023048 2.995681 6.252746 6.319269 6.649696 DTX3L 0.976148907 0.043661316 0.012680504 12.3131789 6.054828 6.270596 6.012527 8.98399 10.157854 9.676959 GLRX3 0.799158265 0.045355733 0.022075536 12.3098614 6.143785 4.389936 3.324375 8.361545 8.011679 7.327219 VPS41 0.970953796 0.043709154 0.012942497 12.30963202 4.815804 4.830496 3.935222 7.556987 8.011679 8.745549 POLR2C 0.899552608 0.044203301 0.016521266 12.30963202 5.056948 3.360637 3.935222 7.556937 7.793829 7.152205 PBLD 1.055802609 0.043540291 0.00974345 12.30892212 3.350997 3.32135 3.764125 7.109557 7.094585 6.942983 CALCOCO1 0.890663262 0.044203301 0.016964954 12.30892212 5.316227 3.32135 4.285996 8.239009 8.314558 6.942983 EIF4E3 0.816133188 0.045165524 0.020964954 12.30892212 3.024504 3.32135 3.764125 5.252045 7.627877 6.942983 ZC3H12A 0.915421403 0.044110923 0.015557673 12.30054642 3.350997 4.413323 5.018694 11.307926 8.033973 6.455366 MED4 0.965487649 0.043778104 0.013173869 12.29750485 3.350997 4.750708 4.944468 7.504712 8.564762 8.03232 ZNF124 0.900528571 0.044203301 0.016434842 12.29547398 2.993831 3.770995 4.944468 6.396698 7.767462 8.564524 CDS1 0.863340849 0.044377262 0.018225927 12.29366246 1.874444 4.413323 2.165421 8.033165 6.237456 5.426231 MGST2 0.904329641 0.044173537 0.016212998 12.29128777 2.993831 2.809601 4.285996 8.270632 6.613395 6.129407 FAM206A 0.782334216 0.045701235 0.023165703 12.29128777 2.993831 3.770995 2.165421 8.139755 6.613395 4.476242 CAPN7 1.000278902 0.043588662 0.01183736 12.29074996 4.682076 4.351315 3.935222 8.301578 7.989035 7.395512 PAIP2 0.963487812 0.043778104 0.013235114 12.28408127 7.112399 6.060401 6.326717 10.052735 9.776594 9.945435 MGC14436 0.976038768 0.043661316 0.012687309 12.27553455 1.874444 3.770995 2.995681 6.396698 6.613395 6.722123 LOC100132891 0.807268839 0.045278798 0.021547465 12.27553455 3.024504 2.406905 2.995681 7.243046 6.613395 4.476242 GNL3 0.905979797 0.044173537 0.016104117 12.2626138 6.52121 6.957749 6.031658 11.019999 10.137404 8.929599 EFR3A 0.86246451 0.044379352 0.018279006 12.25669528 4.639409 3.770995 2.379345 8.254907 7.505595 5.874974 NAE1 1.027632369 0.043577906 0.010641034 12.253864 4.209882 4.351315 2.165421 7.33564 7.627877 7.96648 LOC339803 1.04505476 0.043577906 0.010160599 12.25379949 4.209882 3.872014 4.285996 7.30543 8.668166 7.825039 PPP6C 0.892212902 0.044203301 0.016903709 12.2503371 5.328526 4.911517 3.90836 8.955085 7.91889 7.523109 LOC100130890 0.909235331 0.044173036 0.01595985 12.2426966 8.424205 7.547799 8.859664 10.70401 12.038054 12.989194 MERTK 0.958681654 0.043826549 0.013463083 12.22993628 3.024504 2.406905 2.995681 7.36523 6.608026 5.446557 ALOX5 0.729237285 0.047411805 0.02716162 12.21969441 1.874444 2.023048 2.165421 6.651882 3.134528 5.634184 DCN 0.901177275 0.044203301 0.016407622 12.21165883 8.691047 8.181467 9.374815 11.112348 14.059416 12.301234 ORMDL1 0.960888006 0.043778104 0.013323579 12.16974349 4.682076 5.43468 4.285996 7.976765 8.518072 8.287303 PPP2R2D 0.92966909 0.044037172 0.014834297 12.13683918 4.743564 3.872014 4.754917 8.40494 7.473335 7.640338 TMX2 1.020171365 0.043577906 0.011042531 12.13681501 4.963444 4.389936 4.754917 8.069577 8.564762 8.074602 SNX24 0.957946362 0.043835088 0.013514801 12.1230449 2.201691 4.389936 3.324375 7.25991 6.861783 6.924055 ERCC3 0.90777916 0.044173537 0.016008847 12.11192565 5.779429 4.413323 4.449894 8.173604 8.011679 8.549611 RPL31 1.013673873 0.043581008 0.011320857 12.10998464 9.461799 10.227521 9.996864 13.615329 13.594989 13.134325 STEAP4 0.98781763 0.043626235 0.012259272 12.10266693 6.554045 6.931478 7.317525 10.528731 9.822151 12.309004 SLBP 0.924727384 0.044086036 0.015133038 12.10251707 1.874444 3.872014 3.90836 7.167419 7.505595 6.129407 ASB11 0.973907833 0.043681142 0.012777135 12.07437843 9.761558 9.007473 9.757647 12.248383 13.351524 14.081766 PHF14 0.990993273 0.043626235 0.012164001 12.06201189 3.350997 3.770995 4.724406 8.316805 7.89473 6.942983 GPHN 1.062426074 0.043516135 0.009469207 12.04343421 4.209882 3.770995 3.764125 7.33564 7.53715 7.800057 ASPN 0.896865911 0.044203301 0.016658727 12.03642974 1.874444 4.389936 4.944468 6.814118 8.533804 7.428484 LHPP 0.987648693 0.043626235 0.012266077 12.03271966 3.024504 3.360637 3.764125 7.607339 6.613395 6.649696 METTL6 0.966881685 0.043778104 0.013119428 12.03271966 3.024504 2.023048 2.165421 5.891233 6.613395 5.426231 HERC1 0.977570578 0.043661316 0.012632868 12.02888209 3.839948 2.809601 3.764125 7.856887 6.319269 7.352555 MAN1B1 0.911807656 0.044142622 0.015788363 12.02888209 2.201691 2.809601 3.764125 5.579836 6.549959 7.352555 MRPS21 0.91607175 0.044110923 0.015530453 12.02435655 4.963444 3.360637 3.935222 8.051486 7.066159 7.523109 STAM2 0.877361844 0.044280042 0.017555631 12.02435655 5.779429 4.389936 3.935222 8.139755 8.624754 7.523109 TOMM70A 0.755076599 0.046508764 0.025268459 12.0174967 4.815804 4.736586 5.225216 9.268737 8.402869 6.385515 TRA2A 0.925940018 0.04406867 0.015060905 12.00687014 6.792865 6.311907 7.132367 10.849852 10.378653 9.363984 GLIPR1L2 1.048079436 0.043577906 0.010004764 12.00502808 4.209882 4.830496 5.018694 8.604261 8.200916 8.269212 GPNMB 0.86828546 0.044335719 0.017970058 12.00256867 6.008206 7.458616 7.69729 9.344992 11.290656 11.043888 KIAA1377 0.972797339 0.043681142 0.01285199 11.99109912 4.682076 3.32135 3.90836 7.556937 7.440337 7.492252 GAB1 0.993466638 0.043626235 0.012061926 11.98802334 3.024504 2.023048 2.379345 5.728038 6.608026 5.900694 ZFYVE21 1.058441604 0.043540291 0.009586934 11.94151162 2.201691 2.023048 2.165421 5.743334 6.549959 5.426231 TFAP2E 0.969628504 0.043726704 0.013003062 11.94151162 1.874444 2.809601 2.165421 5.743334 5.306419 6.455366 ARHGAP11A 0.818924497 0.045111103 0.020798231 11.94151162 3.350997 3.770995 2.165421 5.743334 5.857745 7.36177 C8orf4 0.861362665 0.044379352 0.018340252 11.91179602 6.792865 6.092406 7.970268 12.987836 9.666725 9.717557 PARK2 1.069592179 0.043516135 0.009265056 11.91038053 1.874444 2.023048 2.165421 5.448591 5.920411 5.580533 TESK2 1.034321401 0.043577906 0.01041919 11.91038053 1.874444 2.023048 2.379345 5.448591 5.509998 6.385515 PTPRJ 0.896551962 0.044203301 0.016665532 11.91038053 1.874444 3.360637 2.165421 5.448591 5.857745 6.106561 IGIP 0.863347943 0.044377262 0.018219122 11.91038053 1.874444 2.023048 3.764125 5.448591 6.205902 6.051818 LOC100289211 1.052576344 0.043568903 0.009854372 11.89360016 1.874444 2.023048 2.165421 5.448591 6.319269 5.446557 FAM86B2 1.05192565 0.043568903 0.009874787 11.89360016 1.874444 2.023048 2.165421 5.448591 5.936219 5.446557 C4orf21 1.051284078 0.043568903 0.009888397 11.89360016 1.874444 2.023048 2.165421 5.448591 5.857745 5.446557 TMEM164 0.795954361 0.045374706 0.022254508 11.89360016 1.874444 2.023048 4.449894 6.544171 6.205902 5.446557 IMPDH2 0.932369312 0.044025007 0.01470296 11.89115544 5.744513 6.228068 6.031658 9.799885 9.637899 8.66481 ATRX 0.875866815 0.044285705 0.01764818 11.87751933 6.898923 5.297868 5.592916 9.094145 9.321782 9.163078 REEP5 0.915281186 0.044110923 0.015571283 11.87600552 5.897292 6.931478 5.609945 9.179923 9.608485 9.704151 RHOC 0.933141974 0.044025007 0.014682545 11.85051703 6.227577 6.049721 4.754917 9.794456 8.986657 8.834367 C12orf47 1.057290766 0.043540291 0.00966179 11.81556599 1.874444 2.023048 2.165421 5.728038 5.509998 5.446557 KLHL13 0.929241299 0.044037172 0.014861518 11.81556599 2.201691 2.023048 2.165421 5.728038 7.414086 4.562324 ARAP1 0.895471955 0.044203301 0.016719973 11.80079328 3.819732 3.360637 4.449894 6.339437 7.53715 8.010706 LOC285965 0.80438775 0.045327183 0.021737326 11.79595259 4.263463 4.80797 4.449894 6.339437 8.36819 8.232333 NR3C1 1.053621751 0.043568903 0.009813542 11.77838249 6.227577 4.736586 5.974145 9.499787 9.532215 9.570168 USP28 0.829720088 0.044930476 0.020153794 11.77464517 2.993831 2.023048 2.165421 5.728038 6.551443 4.562324 SEPHS1 1.003402787 0.043588662 0.011735284 11.7743835 4.209882 2.406905 3.935222 7.42265 7.767462 6.924055 CPOX 1.048065682 0.043577906 0.010011569 11.77361635 1.874444 2.023048 2.165421 5.320955 5.920411 5.580533 FBX038 1.02667235 0.043577906 0.01071589 11.77361635 1.874444 2.023048 2.379345 5.320955 6.774676 5.580533 LATS1 1.025197695 0.043577906 0.010790745 11.77361635 1.874444 2.023048 2.165421 6.283686 5.165949 5.580533 F2RL1 0.975673109 0.043661316 0.012721334 11.77361635 1.874444 2.023048 2.165421 7.477873 4.797798 5.580533 ACAD8 0.96391037 0.043778104 0.013207894 11.77361635 1.874444 2.023048 2.379345 4.894482 6.861783 5.580533 ADCK1 0.922248271 0.044110923 0.015254849 11.77361635 1.874444 2.023048 2.165421 6.339437 4.539173 5.580533 PHOSPHO2 0.915044201 0.044110923 0.015591698 11.77361635 1.874444 2.023048 2.165421 6.063041 4.539173 5.580533 CDKN2B-AS1 0.904852468 0.044173537 0.016199388 11.77361635 3.024504 2.023048 2.995681 5.705318 7.174648 5.580533 CYP4Z1 0.897254279 0.044203301 0.016627424 11.77361635 1.874444 2.023048 2.165421 8.553743 4.131418 5.580533 EXOSC4 0.896451688 0.044203301 0.016672338 11.76863057 3.350997 2.023048 2.379345 7.748771 5.936219 5.106393 POU5F1 1.052986083 0.043568903 0.009827152 11.76792341 1.874444 2.023048 2.165421 5.579836 5.353925 5.874974 BRDT 1.048139689 0.043577906 0.009997958 11.76792341 1.874444 2.023048 2.165421 5.579836 5.306419 6.924055 RAD51 1.046727287 0.043577906 0.010045594 11.76792341 1.874444 2.023048 2.165421 5.579836 5.317867 5.874974 LOC100505678 1.015144236 0.043581008 0.011259612 11.76792341 1.874444 2.023048 2.165421 5.579836 6.640994 5.091834 RFC3 0.914326436 0.044110923 0.015632528 11.76792341 1.874444 2.023048 2.165421 5.579836 5.920411 4.562324 SMAD9 0.913778613 0.044110923 0.015666553 11.76792341 1.874444 2.023048 2.995681 5.579836 6.613395 5.106393 C9orf66 0.911891068 0.044142622 0.015774753 11.76792341 1.874444 2.023048 2.379345 5.579836 4.608763 6.385515 FMO3 0.848019143 0.044599879 0.019028921 11.76792341 1.874444 2.023048 2.165421 5.579836 4.131418 6.051818 FGFBP2 0.777873576 0.045844227 0.023457639 11.76792341 1.874444 2.023048 2.165421 5.579836 6.043524 3.676349 LOC100652846 0.755261751 0.046505334 0.025237155 11.76792341 1.874444 2.023048 2.165421 5.579836 3.571326 5.882028 PCDHB4 0.66651124 0.050336605 0.033154815 11.76792341 1.874444 2.023048 2.165421 5.579836 5.920411 2.921909 DPAGT1 0.933466077 0.044025007 0.01466213 11.76254379 2.993831 3.770995 2.165421 6.811341 6.549959 6.051818 HMGCL 0.842164271 0.044677344 0.019323579 11.76254379 2.993831 2.023048 2.165421 5.891233 6.549959 4.562324 ZNF451 0.888565127 0.044203301 0.01708064 11.75955411 3.839948 2.023048 2.995681 7.074163 6.551443 5.634184 NHLRC3 0.820908709 0.045095391 0.020664171 11.75955411 1.874444 2.023048 2.995681 6.183122 6.551443 4.146207 WAPAL 0.87596015 0.044285705 0.01763457 11.75447288 4.209882 4.830496 6.031658 7.976765 8.385634 8.705744 DDIT4 1.003656098 0.043588662 0.011728479 11.74746824 3.024504 2.809601 2.995681 7.679787 6.549959 5.900694 A2ML1 0.937771558 0.043986717 0.014465464 11.73936481 7.800655 7.218985 7.481604 10.162171 11.236404 11.353938 NEU1 0.943152023 0.043921714 0.014251786 11.73834788 5.700376 4.413323 5.592916 9.934313 8.928336 7.96648 AICDA 1.057955858 0.043540291 0.00962096 11.72720348 1.874444 2.023048 2.165421 6.063041 5.509998 5.426231 RG9MTD1 0.830974122 0.044867325 0.019991834 11.72720348 1.874444 4.750708 2.165421 6.960054 7.094585 5.426231 KIAA1432 0.996187511 0.043626235 0.011980265 11.71785132 4.963444 3.872014 3.90836 7.42265 7.89473 8.488368 NAALADL2 1.006755671 0.043588662 0.011599183 11.71545003 2.993831 2.406905 2.165421 6.544171 6.237456 5.634184 KIAA0240 0.848789137 0.044567264 0.01895883 11.71545003 2.993831 4.911517 2.995681 6.544171 6.861783 7.492252 BLOC1S2 1.045995957 0.043577906 0.010127254 11.71474695 4.309025 4.80797 4.754917 9.171571 7.845161 8.305171 NDNL2 0.927823987 0.044037172 0.014936373 11.64925523 4.743564 3.360637 3.90836 7.450526 7.793829 7.03218 CAND2 0.831433626 0.044867325 0.019978224 11.64821739 3.819732 2.023048 2.379345 6.811341 4.608763 7.36177 PPP2R2A 0.7860966 0.045579058 0.022866962 11.6475378 4.815804 5.195784 5.389265 9.914429 8.737737 6.649696 FARP2 0.998719712 0.043626235 0.011883634 11.64503997 2.201691 2.406905 2.165421 5.743334 5.317867 6.106561 WDR73 1.026588524 0.043577906 0.010722695 11.64037532 1.874444 2.809601 2.379345 6.063041 5.920411 5.874974 BTN3A2 0.930011726 0.044037172 0.014807077 11.635267 3.839948 3.32135 2.165421 6.063041 6.861783 7.020304 PLEKHF2 0.898751962 0.044203301 0.016552569 11.635267 4.309025 3.32135 2.379345 8.474485 6.861783 5.900694 CIAO1 1.025591798 0.043577906 0.01074311 11.63412807 7.463005 6.270596 6.175931 9.716222 10.987812 10.950464 RBM45 1.033699882 0.043577906 0.0104328 11.63095218 2.201691 2.023048 2.165421 5.705318 5.317867 6.106561 PMS1 0.934221799 0.04402131 0.014609051 11.63095218 2.201691 2.023048 2.165421 5.705318 5.936219 4.790662 LRRC40 0.863451489 0.044377262 0.018205512 11.63095218 2.993831 2.023048 2.165421 5.705318 6.640994 4.790662 LDB3 0.747189045 0.046789913 0.025828513 11.63095218 3.024504 5.297868 2.165421 5.705318 6.78473 7.695565 CNOT6L 0.863404213 0.044377262 0.018212317 11.62148856 4.963444 4.413323 6.450701 9.68135 8.502167 8.03232 AQP3 0.843739594 0.044645837 0.019218101 11.61657734 1.874444 5.487673 3.935222 7.477873 7.473335 7.180104 BMPR2 0.93241384 0.044025007 0.01468935 11.59480409 5.335413 4.750708 3.935222 7.531061 8.220489 8.870819 ZMYM6 0.920155549 0.044110923 0.015322218 11.57371071 2.993831 2.023048 3.324375 6.857154 6.551443 5.446557 DCAF11 0.842390772 0.044657496 0.019294318 11.5672755 5.700376 4.389936 3.90836 8.254907 7.440337 7.943848 CCDC6 1.078985181 0.043516135 0.009006465 11.55443607 5.658609 5.195784 5.702912 9.154721 9.188984 9.192178 UBXN4 1.0243232 0.043577906 0.01085199 11.55443607 5.658609 3.770995 6.072169 9.452312 9.188984 8.997112 SEC22A 0.873465326 0.044299467 0.017717591 11.55012205 1.874444 2.809601 2.165421 6.339437 6.237456 4.476242 ZNF680 1.024881301 0.043577906 0.01079755 11.54594574 1.874444 2.406905 2.165421 5.448591 5.936219 5.634184 CSNK2A2 0.893502984 0.044203301 0.016842463 11.54594574 3.819732 2.406905 3.90836 7.450526 5.936219 7.218312 RPPH1 0.815855258 0.045173526 0.020991494 11.54594574 3.350997 2.406905 2.165421 4.739845 5.936219 6.942983 LOC100129269 0.897025715 0.044203301 0.016645117 11.53862847 4.639409 2.809601 3.764125 6.252746 7.292524 8.809543 LOC731275 0.922615043 0.044091888 0.015205172 11.52694552 3.024504 2.406905 2.165421 5.095353 6.551443 6.32627 SNAPC3 0.924732264 0.044086036 0.015126233 11.52222119 2.201691 2.406905 3.90836 5.728038 6.549959 7.020304 KCNJ11 0.863169997 0.044377262 0.018239537 11.52222119 2.201691 2.406905 2.165421 5.728038 4.539173 6.106561 AKAP5 0.771395749 0.046066162 0.02398639 11.52092771 3.024504 2.023048 5.225216 6.550689 6.189775 7.327219 SMARCA2 0.965661259 0.043778104 0.013160259 11.49949418 4.263463 3.872014 4.724406 7.531061 8.609988 7.395512 PSPC1 0.910989368 0.044159136 0.015844845 11.48318318 4.209882 4.736586 5.723602 9.245052 8.502167 7.553321 IWS1 0.925811382 0.04407613 0.01508132 11.48237798 2.993831 3.770995 2.379345 6.544171 7.191402 5.900694 MRE11A 0.872538992 0.044299467 0.017758421 11.48237798 3.839948 3.32135 2.379345 7.771052 6.205902 5.900694 RPL26L1 0.768852671 0.046108296 0.024143586 11.47630214 5.263699 4.80797 2.379345 7.074163 6.608026 8.784285 SH3BGRL2 0.646218277 0.051798486 0.035717591 11.46899565 3.024504 2.023048 2.165421 6.544171 6.373501 2.921909 HRH1 0.718586344 0.047781016 0.028061245 11.44096074 3.350997 3.360637 4.449894 5.026959 7.96603 7.180104 ZYG11B 0.944232361 0.043921714 0.014176931 11.42451014 5.316227 2.023048 4.285996 7.726141 8.011679 7.800057 ALMS1 0.95052539 0.043900827 0.01387887 11.42011732 1.874444 2.406905 2.165421 4.894482 5.920411 5.900694 FOXA1 0.764062786 0.046193441 0.024520585 11.42011732 3.024504 2.406905 2.165421 9.196483 5.920411 3.630092 C1S 0.765808082 0.046178907 0.024419871 11.41980247 6.949166 7.0583 8.26876 9.102956 11.782226 10.859668 PCCA 0.890071925 0.044203301 0.016992174 11.41300488 3.839948 2.023048 2.165421 5.320955 6.189775 7.352555 NARS2 0.935677479 0.043994974 0.014541681 11.40732183 1.874444 2.809601 2.379345 5.891233 6.549959 5.091834 MTCH2 0.902618509 0.044190907 0.01631031 11.38978011 1.874444 2.809601 2.165421 4.718672 6.319269 6.106561 TTC3P1 0.73673459 0.047188004 0.026630146 11.38978011 1.874444 2.809601 2.995681 7.36523 6.319269 3.676349 INPP5B 0.910728101 0.044159136 0.015858455 11.38460674 4.963444 4.830496 5.544653 7.656039 9.053666 8.758577 PPP1R8 0.942893961 0.043921714 0.014258591 11.35870594 4.209882 3.770995 3.90836 7.976765 7.414086 6.722123 TMEM203 0.953761419 0.043857532 0.013722355 11.3563295 3.024504 2.809601 3.764125 7.177844 7.269549 5.900694 PLEKHH2 0.953940044 0.043857532 0.013708744 11.34974248 5.328526 6.03611 5.723602 9.968463 9.228189 8.488368 PILRB 0.998576253 0.043626235 0.011897244 11.34903893 5.658609 5.195784 4.508334 8.700282 8.385634 9.153246 LOH12CR1 0.840129193 0.044722631 0.01947329 11.3347672 3.819732 2.023048 2.379345 5.705318 6.205902 5.882028 ETAA1 0.641134626 0.052118775 0.036382443 11.33365004 1.874444 2.023048 2.995681 6.498222 5.920411 2.921909 COPS7A 0.913850137 0.044110923 0.015659748 11.32269771 3.819732 3.360637 2.165421 8.033165 6.861783 5.634184 STK17A 0.855649851 0.044416666 0.018578428 11.31510372 6.267718 6.42919 4.724406 9.929368 8.97518 8.549611 BBS7 0.666321665 0.050341041 0.033165703 11.27948081 5.328526 2.406905 2.379345 6.063041 6.640994 5.874974 TMOD2 0.803226477 0.045338539 0.021848928 11.26510959 1.874444 2.406905 2.165421 4.013424 5.857745 5.900694 EIF2C4 0.711128735 0.048057698 0.028664852 11.26510959 4.682076 2.406905 2.165421 5.743334 6.237456 5.900694 ZBTB8A 0.958485289 0.043826549 0.013476693 11.26401148 9.132739 8.75372 9.124675 11.760466 12.618324 13.098908 TMED3 0.778396473 0.045844227 0.023444029 11.2609987 6.344798 4.389936 3.935222 8.604261 8.077554 7.428484 RNF139 0.889186622 0.044203301 0.017039809 11.26056386 5.316227 5.297868 6.410545 8.854326 8.791075 8.986077 ARHGEF9 0.927323038 0.044037172 0.014956788 11.25713732 1.874444 3.32135 3.764125 6.814118 5.936219 7.033813 ARHGEF11 0.870617246 0.044325295 0.017845526 11.25713732 4.815804 3.32135 4.508334 6.814118 8.469821 7.523109 CORO1A 0.983330653 0.043626235 0.012456618 11.2465455 1.874444 2.023048 3.764125 7.243046 5.306419 7.255535 RPS27 0.970090329 0.043726704 0.012982647 11.2264398 11.434209 11.615306 12.321759 15.338386 14.923037 15.410824 ADHFE1 0.914415019 0.044110923 0.015612113 11.21340538 3.839948 2.023048 3.90836 6.339437 6.78473 7.395512 CD52 1.040693272 0.043577906 0.010289895 11.21183234 1.874444 2.023048 2.165421 5.320955 5.509998 7.327219 SIDT1 1.010994828 0.043581008 0.011416128 11.21183234 1.874444 2.023048 2.165421 7.33564 5.509998 5.106393 FEM1B 1.010819556 0.043581008 0.011422933 11.21183234 1.874444 2.023048 2.165421 7.177844 5.509998 5.106393 FGFR1OP 1.009234095 0.043581008 0.011456958 11.21183234 1.874444 2.023048 2.165421 7.631894 5.509998 5.091834 DDX60 1.008160778 0.043581008 0.011504593 11.21183234 1.874444 2.023048 2.165421 6.339437 5.509998 5.106393 LOC157381 0.976998501 0.043661316 0.012653283 11.21183234 1.874444 2.023048 2.165421 4.894482 5.509998 6.649696 SLC30A1 0.940058283 0.043921714 0.014360667 11.21183234 1.874444 2.023048 2.165421 7.976765 5.509998 4.562324 THAP1 0.935538795 0.043994974 0.014555291 11.21183234 1.874444 2.023048 2.165421 7.450526 5.509998 4.562324 GPR171 0.930880176 0.044025007 0.014777816 11.21183234 1.874444 2.023048 2.165421 8.222933 5.509998 4.476242 CCT6P1 0.912766829 0.044110923 0.015727799 11.21183234 1.874444 2.023048 2.165421 6.664985 5.509998 4.476242 SIAE 0.854483098 0.044464174 0.018629466 11.21183234 1.874444 2.023048 2.379345 7.177844 5.509998 4.146207 CYP4V2 0.822966138 0.045019115 0.020548486 11.21183234 1.874444 2.023048 2.995681 6.664985 5.509998 4.476242 MYBPC1 0.771370906 0.046066162 0.024 11.21183234 1.874444 2.023048 2.165421 9.621288 5.509998 2.921909 CTNND2 0.715005996 0.047877006 0.028311671 11.21183234 1.874444 2.023048 2.165421 7.274575 5.509998 2.921909 FAM113B 0.694595008 0.048864786 0.030299422 11.21183234 1.874444 2.023048 2.165421 2.820813 5.509998 7.03218 BEX5 0.656398353 0.050987756 0.034200749 11.21183234 1.874444 2.023048 2.379345 6.183122 5.509998 2.921909 FLJ26245 0.653636626 0.051180942 0.034561415 11.21183234 1.874444 2.023048 2.165421 5.743334 5.509998 2.921909 NALCN 0.648182042 0.05162501 0.035343314 11.21183234 1.874444 2.023048 2.165421 2.820813 5.509998 5.900694 TMEM159 0.629012622 0.053255542 0.038219122 11.21183234 1.874444 2.023048 2.995681 6.811341 5.509998 2.921909 RASGRP1 0.819946491 0.045095391 0.020739027 11.2034071 1.874444 3.872014 3.90836 7.394225 6.319269 5.874974 ZNF192 0.966920903 0.043778104 0.013112623 11.19023993 4.639409 4.413323 2.165421 7.109557 8.011679 7.897492 HNMT 0.966984728 0.043778104 0.013105818 11.18941401 3.819732 4.830496 4.754917 7.957464 8.314558 7.611911 ANP32A 0.878834176 0.044280042 0.017501191 11.18935604 3.839948 3.770995 2.995681 7.504712 7.25505 5.874974 FTSJD1 0.630364753 0.053156193 0.038025179 11.18868799 4.309025 3.360637 2.995681 7.792994 7.066159 4.146207 ZDHHC4 0.949818602 0.043900827 0.013906091 11.16928622 5.056948 2.406905 4.285996 8.105092 7.767462 7.395512 LMLN 0.967253712 0.043778104 0.013092208 11.16213696 2.201691 3.872014 4.754917 7.274575 7.793829 7.352555 CUL3 0.951220022 0.043900827 0.013844845 11.16141718 4.639409 5.195784 2.379345 8.173604 8.119857 7.640338 CREG2 1.008189306 0.043581008 0.011497788 11.15393926 1.874444 2.406905 2.165421 6.067497 5.353925 5.580533 PDE8B 0.878195452 0.044280042 0.017535216 11.15393926 1.874444 3.32135 2.165421 5.705318 5.353925 6.106561 ATL3 0.873630311 0.044299467 0.017703981 11.15393926 1.874444 2.023048 3.764125 6.811341 5.353925 5.900694 DNMBP-AS1 0.943646061 0.043921714 0.014210956 11.14557916 1.874444 2.023048 2.379345 4.894482 5.857745 5.580533 SPATA13 0.926998618 0.044037172 0.014970398 11.14219276 3.839948 4.736586 4.285996 8.376156 7.31791 7.352555 AP1G1 0.926568136 0.04406867 0.015015992 11.13865725 6.143785 4.413323 4.449894 9.621288 8.94019 7.668215 FABP4 0.82065708 0.045095391 0.020677782 11.13426505 6.267718 7.512784 7.593473 9.744652 9.783191 11.713056 ZNF273 0.967298321 0.043767668 0.013077237 11.13099124 5.304463 3.360637 4.724406 8.206677 8.200916 8.03232 SRPRB 0.914286587 0.044110923 0.015639333 11.08745656 5.056948 4.389936 3.90836 8.527804 7.473335 7.523109 NCL 0.943988068 0.043921714 0.014183736 11.07456727 7.968408 8.041069 8.011136 11.510248 11.483245 10.816712 PIP 1.016445978 0.043581008 0.011198367 11.07138096 1.874444 2.406905 2.165421 10.987062 5.306419 5.634184 B3GNT1 0.846234275 0.044641179 0.019132358 11.07138096 1.874444 2.809601 2.165421 4.341916 7.505595 5.634184 MZT2A 0.795748551 0.045395954 0.022306907 11.07138096 1.874444 2.406905 2.165421 8.087444 3.571326 5.634184 AKR7L 0.766217379 0.046178907 0.024392651 11.07138096 1.874444 2.809601 2.165421 4.013424 6.319269 5.634184 DLD 0.851494518 0.044490827 0.018786662 11.06865296 5.779429 4.351315 3.90836 7.771052 7.819723 8.175185 ARMC10 0.977986502 0.043661316 0.012605648 11.06605162 3.024504 2.406905 2.379345 5.728038 7.094585 5.874974 LOC100134229 0.897470529 0.044203301 0.016593399 11.06605162 4.815804 2.406905 2.995681 7.748771 7.91889 5.874974 CCDC71L 0.922001551 0.044110923 0.015261654 11.02551715 4.815804 5.297868 4.285996 7.748771 7.870158 9.346832 ZMYM6NB 0.850220115 0.044510429 0.018858115 11.02477713 4.263463 2.023048 2.165421 7.726141 6.551443 5.091834 STX7 0.776823167 0.045858868 0.023559034 11.01980527 4.309025 3.770995 2.995681 7.771052 7.292524 5.426231 PIAS1 0.95614524 0.043840967 0.01362096 11.01604925 2.993831 3.360637 3.90836 7.177844 6.861783 6.455366 ZBTB33 0.768143371 0.046157531 0.024253147 11.00704303 3.350997 2.809601 3.324375 7.037879 6.78473 4.790662 RBP1 0.928882195 0.044037172 0.014875128 11.00193045 4.309025 3.360637 2.995681 6.664985 9.418172 6.455366 ARID4B 0.920109223 0.044110923 0.015342634 10.98688406 5.056948 4.911517 6.054038 8.514658 9.237827 8.407967 DDX47 1.002884624 0.043588662 0.011742089 10.97895094 4.639409 4.750708 4.724406 9.154721 8.181074 7.748756 GIMAP8 0.751036617 0.046646446 0.025542021 10.96008643 3.024504 2.023048 3.764125 4.341916 6.861783 7.218312 LPCAT4 0.928018107 0.044037172 0.014922763 10.953543 1.874444 3.32135 2.379345 5.095353 6.774676 6.587378 PDZD11 0.846700263 0.044634679 0.01909425 10.953543 2.201691 3.32135 4.754917 7.42265 6.774676 6.32627 PAR-SN 0.961199325 0.043778104 0.013316774 10.93365673 2.993831 3.360637 2.165421 6.811341 6.189775 6.051818 IFNGR1 0.928374143 0.044037172 0.014895543 10.90801917 5.700376 3.770995 4.285996 9.137671 8.668166 7.218312 RSAD2 0.617758663 0.054216311 0.039804695 10.90461125 4.743564 4.389936 4.944468 5.320955 8.220489 8.391335 RBM22 0.865998941 0.044377262 0.018092548 10.89925185 4.209882 4.351315 2.995681 7.656039 8.119857 6.106561 ADPGK 0.805179508 0.045318476 0.021682205 10.89925185 4.209882 3.32135 2.379345 7.656039 6.043524 5.882028 TRDMT1 0.932378568 0.044025007 0.014696155 10.89232761 5.335413 5.43468 3.935222 7.897963 8.87992 8.534542 FGD3 0.796761073 0.045374042 0.02220279 10.88444106 3.024504 2.023048 3.90836 7.210813 4.608763 7.352555 RSRC1 1.032910817 0.043577906 0.010480436 10.87861515 1.874444 2.023048 2.165421 6.063041 5.317867 5.446557 CASP3 1.030768928 0.043577906 0.010548486 10.87861515 1.874444 2.023048 2.165421 6.283686 5.317867 5.426231 LRAT 0.918557887 0.044110923 0.015397074 10.87861515 1.874444 3.32135 2.165421 6.664985 5.317867 5.900694 C11orf51 0.861007243 0.044379352 0.018360667 10.87861515 1.874444 3.770995 2.165421 6.244586 5.317867 6.32627 LOC728218 0.878639427 0.044280042 0.017507996 10.85703452 6.45321 2.023048 5.389265 8.051486 8.829823 9.113234 NARG2 0.938377207 0.043986717 0.014451854 10.85147085 4.639409 3.770995 3.90836 7.210813 7.713236 7.352555 OCLN 0.706349851 0.048309794 0.029167744 10.83888895 4.639409 6.044198 2.165421 8.757204 8.077554 5.882028 IMP3 0.858024092 0.044387761 0.018462062 10.81914598 5.700376 4.389936 4.508334 8.139755 7.91889 7.943848 DAD1 0.983634974 0.043626235 0.012429398 10.81517367 2.201691 2.809601 2.165421 6.244586 5.936219 5.446557 UFSP2 0.859346492 0.044387761 0.018428037 10.80625082 4.815804 3.360637 2.379345 7.210813 6.794431 6.73963 ZNF449 1.025423213 0.043577906 0.010763525 10.79263902 1.874444 2.023048 2.165421 5.728038 5.306419 5.426231 GPR146 1.015138545 0.043581008 0.011266417 10.79263902 1.874444 2.023048 2.165421 5.320955 5.306419 6.587378 ZNF696 0.991721452 0.043626235 0.012136781 10.79263902 1.874444 2.406905 2.165421 7.177844 5.306419 5.426231 MET 0.724924194 0.047570884 0.027501191 10.79263902 1.874444 5.362142 2.165421 8.447068 5.306419 5.882028 MUC20 0.920486671 0.044110923 0.015302484 10.78966854 4.309025 3.360637 4.449894 8.39062 7.740604 6.618407 ZSCAN12P1 0.884972008 0.044203301 0.017223545 10.78127489 4.209882 4.389936 5.592916 8.014609 8.402869 7.640338 ABHD14B 0.903713425 0.044173537 0.016253828 10.76248877 5.304463 3.32135 5.225216 7.726141 8.077554 8.732403 C14orf93 0.943579603 0.043921714 0.014217761 10.74462573 1.874444 2.023048 2.165421 5.448591 4.797798 5.874974 CCDC90B 0.787857436 0.045562713 0.022750595 10.74462573 4.815804 2.023048 2.165421 5.448591 7.187136 6.455366 SPAM1 0.774978047 0.045974332 0.023762504 10.74462573 1.874444 2.023048 2.165421 5.448591 6.189775 3.676349 RSPO1 0.761279466 0.046345577 0.024778496 10.74462573 4.263463 2.023048 2.165421 5.448591 6.205902 5.900694 KIAA0825 0.955729095 0.043840967 0.013654985 10.73201389 2.993831 3.360637 4.449894 6.396698 7.598264 7.873743 HHAT 1.023123237 0.043577906 0.010913236 10.72948777 1.874444 2.023048 2.165421 5.448591 5.353925 5.446557 SIX1 0.987365168 0.043626235 0.012286492 10.72948777 1.874444 2.023048 2.165421 5.026959 6.205902 5.446557 ACVR1C 0.963508596 0.043778104 0.013228309 10.72948777 1.874444 2.023048 2.379345 5.026959 6.319269 5.446557 LOC154822 0.963393158 0.043778104 0.013241919 10.72948777 1.874444 2.023048 2.165421 4.894482 6.043524 5.446557 ATP2B3 0.935013005 0.044003812 0.014589316 10.72948777 1.874444 2.023048 2.165421 4.739845 5.936219 5.446557 PLGLA 0.790578421 0.045525452 0.022638312 10.72948777 3.819732 2.023048 2.165421 5.705318 5.920411 5.446557 ZNF467 0.682775806 0.049399307 0.031390269 10.72948777 1.874444 2.023048 2.379345 6.244586 3.134528 5.446557 PPA2 0.89690072 0.044203301 0.016651922 10.72492834 6.054828 4.750708 5.723602 8.173604 9.303543 9.163078 PDE7B 0.684367741 0.049360973 0.031255529 10.71189147 3.819732 4.911517 4.508334 5.448591 8.332658 8.095288 ZNF32 0.943698595 0.043921714 0.014204151 10.70199538 4.639409 3.872014 2.165421 6.954147 7.740604 7.291822 PTX3 0.720388741 0.047703746 0.027903368 10.70199538 2.993831 3.872014 5.974145 7.33564 7.107836 7.291822 DAB2IP 0.863624095 0.044377262 0.018185097 10.70146591 2.993831 4.351315 3.935222 7.771052 6.608026 6.69026 HIGD2A 0.99130026 0.043626235 0.012157196 10.69672051 5.856559 4.80797 5.544653 8.98399 8.804107 8.96375 LOC100507217 0.889166409 0.044203301 0.017046614 10.68790096 7.530567 7.033812 6.489771 10.948474 10.467346 9.584871 SEC13 0.846717512 0.044634679 0.019087445 10.68365704 5.744513 4.351315 3.935222 8.346785 8.119857 7.352555 PPA1 0.85309444 0.044464174 0.018697516 10.67911006 5.658609 5.362142 6.355801 11.105787 9.075328 7.943848 SUCLG2 0.782725706 0.045701235 0.023131677 10.67762591 4.639409 4.389936 3.90836 7.856887 8.055928 6.129407 E2F6 0.833391017 0.044797567 0.019816264 10.67486761 3.350997 4.351315 5.723602 7.631894 7.767462 7.825039 CCDC34 0.918173429 0.044110923 0.015417489 10.67483163 3.350997 3.770995 4.508334 7.937902 7.187136 6.73963 RGS1 0.701247734 0.048630415 0.029739367 10.6738375 6.736762 6.849665 9.532856 11.317421 10.152769 10.497297 FAM96A 1.01943571 0.043577906 0.011062947 10.6672219 2.201691 2.023048 2.165421 7.897963 5.306419 5.580533 CCDC51 1.015350863 0.043581008 0.011232392 10.6672219 1.874444 2.023048 2.165421 5.320955 5.353925 5.580533 INE2 0.975977483 0.043661316 0.012694114 10.6672219 2.201691 2.023048 2.165421 5.026959 6.549959 5.580533 C14orf132 0.954925294 0.043840967 0.013695815 10.6672219 2.201691 2.023048 2.165421 4.894482 6.551443 5.580533 ST8SIA1 0.816022511 0.045165524 0.020971759 10.6672219 3.819732 2.023048 2.165421 6.396698 5.509998 5.580533 AGPAT9 0.800141265 0.045343942 0.022004083 10.6672219 2.201691 4.389936 2.165421 6.498222 6.319269 5.580533 TDP2 0.797733127 0.045355733 0.022129976 10.6672219 4.309025 2.406905 2.165421 6.063041 6.794431 5.580533 MCM10 0.893885177 0.044203301 0.016822048 10.66206395 2.201691 2.023048 2.165421 5.579836 6.794431 4.476242 ENOX2 0.841389625 0.044701668 0.019385505 10.66206395 3.839948 2.809601 2.165421 5.579836 6.237456 6.587378 DPY19L2P3 0.825937784 0.044948812 0.02035182 10.66206395 1.874444 3.32135 2.165421 5.579836 5.317867 5.580533 GRIA3 0.763755974 0.046221625 0.024585233 10.66206395 2.201691 2.023048 2.165421 5.579836 6.549959 3.630092 PHYH 0.857572809 0.044387761 0.018482477 10.65692621 1.874444 2.023048 3.764125 7.177844 6.861783 4.562324 HADH 0.877630451 0.044280042 0.017548826 10.65319674 4.743564 2.809601 3.90836 8.156778 8.098861 6.051818 MBTPS1 0.862072188 0.044379352 0.018292617 10.62630663 6.054828 4.750708 4.285996 9.388882 8.2398 7.695565 AQR 0.926734837 0.044037172 0.014984008 10.60034028 4.309025 5.487673 4.754917 8.768324 8.160956 7.825039 DNAL1 0.972558852 0.043681142 0.012865601 10.59186492 6.792865 6.702075 6.601009 9.687221 10.227229 10.106959 PRCP 0.951029594 0.043900827 0.013858455 10.58458229 4.309025 4.389936 3.324375 7.582358 7.793829 7.03218 C2orf74 1.021297856 0.043577906 0.010967676 10.57937753 1.874444 2.023048 2.165421 5.252045 6.861783 5.426231 PLXNC1 1.02074957 0.043577906 0.011022116 10.57937753 1.874444 2.023048 2.165421 5.252045 6.237456 5.426231 FLVCR1-AS1 1.001630305 0.043588662 0.011803334 10.57937753 1.874444 2.023048 2.165421 5.705318 5.165949 5.426231 LOC152024 0.988989346 0.043626235 0.012211637 10.57937753 1.874444 2.023048 2.165421 5.026959 6.861783 5.426231 RPGRIP1L 0.959230227 0.043826549 0.013442668 10.57937753 1.874444 2.023048 2.165421 4.894482 5.920411 5.426231 DCDC2 0.946164804 0.043900827 0.014096632 10.57937753 3.024504 2.023048 2.379345 6.396698 5.920411 5.426231 TSC22D1-AS1 0.937640342 0.043986717 0.014472269 10.57937753 1.874444 2.023048 2.165421 5.728038 4.797798 5.426231 ALDH6A1 0.935806978 0.043994974 0.014521266 10.57937753 1.874444 2.023048 2.165421 4.718672 6.237456 5.426231 SEPSECS 0.911173577 0.044159136 0.01582443 10.57937753 1.874444 2.023048 2.379345 4.718672 6.189775 5.426231 MOSPD2 0.892813325 0.044203301 0.016862879 10.57937753 1.874444 2.023048 2.165421 5.728038 4.539173 5.426231 BTNL8 0.891969836 0.044203301 0.016910514 10.57937753 1.874444 2.023048 2.165421 5.705318 4.539173 5.426231 REPS2 0.806840211 0.045297753 0.021586254 10.57937753 2.201691 2.023048 4.449894 6.183122 7.107836 5.426231 HSD17B7P2 0.658489659 0.050764584 0.033936033 10.57937753 1.874444 2.023048 2.165421 2.820813 6.237456 5.426231 TBPL1 0.868745927 0.044335719 0.017929228 10.57482242 5.328526 3.872014 2.379345 7.274575 7.819723 7.180104 ERRFI1 0.76950338 0.046076407 0.024085063 10.56465753 8.129608 7.218985 9.395543 12.831614 10.911585 10.62016 CSTF2T 0.652979968 0.051221132 0.034669616 10.56350303 3.024504 2.406905 2.995681 6.396698 6.549959 3.676349 RPIA 0.950713298 0.043900827 0.013872065 10.55912404 4.639409 4.351315 3.935222 7.33564 7.53715 8.232333 IPO9 0.90217415 0.044190907 0.01636475 10.55548897 6.45321 5.661685 5.217616 8.65307 9.570854 9.061607 AFAP1L2 0.739403307 0.047109709 0.026429398 10.554595 2.993831 3.360637 2.995681 6.395481 7.440337 4.562324 PHF17 0.948661669 0.043900827 0.013953726 10.54159207 6.648293 4.911517 6.282905 9.204692 9.680925 9.724213 PRKCH 0.815060744 0.045182971 0.021058864 10.53752674 2.993831 3.32135 5.225216 6.183122 7.066159 8.622681 TMEM106C 0.928314981 0.044037172 0.014902348 10.53747095 4.209882 4.911517 3.90836 7.607339 8.055928 7.36177 MCFD2 1.016733182 0.043581008 0.011191562 10.53499494 5.491121 5.340619 5.018694 8.745998 8.737737 8.650903 HSD17B8 0.931853363 0.044025007 0.01473018 10.52903112 1.874444 2.809601 2.165421 5.743334 6.205902 5.106393 YARS2 0.92969913 0.044037172 0.014827492 10.52903112 3.024504 2.809601 2.165421 6.544171 6.205902 5.426231 GSTZ1 0.91699256 0.044110923 0.015469207 10.52903112 2.201691 2.809601 3.764125 6.651882 6.205902 6.129407 PHC3 0.98879688 0.043626235 0.012225247 10.50600765 6.707871 6.762934 6.891005 9.858293 10.284148 10.224304 CNNM1 0.913095647 0.044110923 0.015700578 10.50151677 4.682076 3.770995 5.018694 7.274575 8.296229 8.074602 CPZ 0.803809452 0.045338539 0.021808098 10.49767338 2.993831 2.809601 3.935222 5.252045 6.640994 7.327219 LOC643401 0.947817387 0.043900827 0.014021776 10.49719397 6.765086 6.311907 6.636262 9.403221 10.137404 10.157018 MAB21L1 0.794537024 0.04542938 0.022381763 10.48193895 2.201691 3.32135 2.995681 4.739845 6.774676 6.385515 KBTBD7 0.90314733 0.044190907 0.016283089 10.47322353 3.350997 2.023048 2.165421 5.095353 6.189775 6.73963 LOC286437 0.792635642 0.045439604 0.02248656 10.46692373 5.304463 5.195784 5.974145 7.450526 9.601037 8.692228 TPP2 0.822731902 0.045019115 0.020568901 10.45111058 4.815804 2.809601 3.935222 7.42265 7.767462 6.195186 GHITM 0.805150151 0.045318476 0.021695815 10.44058169 5.982974 3.360637 4.724406 9.367104 7.942653 7.020304 HLA-DPA1 0.782456045 0.045701235 0.023145288 10.43911481 5.491121 4.750708 6.410545 8.875048 7.473335 9.863386 FGD5-AS1 0.920767918 0.044110923 0.015295679 10.43676358 6.820119 6.072636 6.175931 10.203722 9.722706 9.133378 XRN1 1.01310111 0.043581008 0.011348078 10.43579992 5.304463 5.340619 4.449894 8.553743 8.724089 8.534542 BAZ2B 0.928759132 0.044037172 0.014881933 10.43487513 4.963444 2.023048 5.389265 8.346785 8.453372 7.611911 FKTN 0.911125649 0.044159136 0.015831235 10.43344278 5.491121 2.406905 5.225216 7.504712 8.737737 8.60836 C15orf44 0.979706032 0.043626235 0.012565498 10.43266492 4.309025 3.872014 2.379345 7.167419 7.25505 7.352555 ERICH1 0.87889079 0.044280042 0.017494386 10.41438808 1.874444 4.413323 2.995681 5.252045 7.793829 7.668215 CD3D 0.708057305 0.048268527 0.029001021 10.41199214 2.993831 2.809601 5.702912 7.607339 6.189775 6.73963 CSF2RA 0.839640975 0.044722631 0.019520925 10.40835225 2.993831 2.023048 3.764125 6.664985 6.373501 5.446557 LOC286135 0.817273762 0.045152347 0.020886696 10.40835225 2.993831 2.406905 4.449894 6.067497 6.373501 6.942983 ANTXR1 0.869725818 0.044335719 0.017895202 10.40325953 4.743564 5.195784 6.175931 8.122528 8.892178 8.79697 ELMOD2 0.927065287 0.044037172 0.014963593 10.40238701 2.201691 2.406905 2.165421 5.026959 5.857745 5.580533 KIF2A 0.798579852 0.045355733 0.022089146 10.40238701 2.201691 3.872014 4.285996 8.39062 6.613395 5.580533 TCEAL7 0.837435238 0.044763248 0.019630487 10.39735712 2.201691 2.406905 5.389265 5.579836 8.296229 7.523109 CRYZ 0.830077804 0.044900952 0.020109561 10.3950123 4.309025 2.406905 2.995681 7.144104 6.373501 5.900694 MID1 0.814576698 0.045212649 0.021130997 10.3950123 1.874444 4.389936 2.995681 7.25991 6.373501 5.634184 GPM6A 0.94915183 0.043900827 0.013933311 10.39343918 1.874444 2.023048 2.995681 5.252045 5.920411 6.195186 BTBD1 0.852520272 0.044480228 0.018739707 10.38037581 6.143785 4.911517 2.165421 8.447068 7.793829 8.287303 WDR6 0.972198325 0.043681142 0.012892821 10.36620726 5.779429 5.195784 6.355801 9.52623 9.1177 9.153246 RNF113B 0.951406849 0.043900827 0.013831235 10.36408679 3.024504 2.809601 4.508334 6.183122 7.819723 7.695565 ATIC 0.613358763 0.054636493 0.040396734 10.35455279 3.024504 2.023048 2.379345 6.396698 6.189775 2.921909 CCT4 0.980402673 0.043626235 0.012551888 10.35170267 6.054828 6.391145 5.702912 9.252991 9.426624 9.635186 HSP90B1 0.843906228 0.044645837 0.019211296 10.35122978 6.820119 4.80797 5.544653 10.857682 8.916384 8.11568 SFMBT1 0.814038065 0.045212649 0.021165022 10.34689834 3.350997 2.023048 4.724406 6.395481 6.794431 6.722123 SEMA3D 0.602506556 0.05597852 0.042301463 10.34582098 3.024504 2.406905 2.165421 6.395481 6.205902 2.921909 MEAF6 0.78612346 0.045579058 0.022853351 10.33347257 5.779429 6.35207 5.596986 10.21189 9.148683 7.748756 ARGFX 0.92642488 0.04406867 0.01502688 10.31431089 6.186289 5.148082 5.225216 8.514658 8.951948 9.123341 RPL13AP20 0.970688207 0.043709154 0.012962913 10.30759026 11.4075 11.947432 11.784204 14.999282 14.844591 15.313067 SOX17 0.596059306 0.056713306 0.043476012 10.29583919 2.993831 2.023048 2.379345 5.743334 2.265287 8.357484 TCTA 0.947887109 0.043900827 0.014014971 10.29379662 5.304463 4.389936 4.944468 7.995811 8.668166 8.11568 CUTA 1.019714214 0.043577906 0.011049337 10.28877632 6.898923 6.849665 6.769247 10.834062 10.132246 10.147144 GDI2 0.893232498 0.044203301 0.016849268 10.2884409 5.056948 3.872014 4.754917 7.918071 8.4199 7.291822 MAEA 0.819769302 0.045111103 0.0207574 10.28435845 5.335413 7.197097 5.217616 8.955085 8.579995 10.086439 POLR1E 0.829554173 0.044930476 0.020160599 10.28287953 5.056948 6.03611 3.764125 8.41912 7.740604 8.472642 UBA7 0.90473174 0.044173537 0.016206193 10.28039902 3.024504 2.809601 4.508334 5.891233 7.870158 7.553321 PUM1 0.9334459 0.044025007 0.014668935 10.27885202 6.008206 5.362142 5.217616 8.579223 8.829823 8.974957 PPP4R2 0.99695544 0.043626235 0.011944879 10.27460209 3.024504 2.809601 2.165421 6.067497 6.043524 6.385515 MUTYH 0.767642677 0.046164489 0.024315754 10.26889971 5.753024 3.360637 3.935222 6.396698 7.440337 9.113234 TMEM176B 0.927628533 0.044037172 0.014943178 10.22279952 5.658609 5.340619 6.355801 9.012327 10.12707 8.678584 NEO1 0.772140631 0.046057921 0.023923784 10.20744665 4.209882 3.32135 3.90836 7.25991 7.68534 5.580533 PRKY 0.884401139 0.044203301 0.017250766 10.20120189 3.819732 4.389936 3.324375 6.252746 7.740604 7.611911 NOTCH2NL 0.754295995 0.04655221 0.025314733 10.18939489 3.024504 2.406905 2.165421 6.063041 6.373501 4.146207 PPIG 0.895218516 0.044203301 0.016747193 10.18806548 5.779429 4.80797 4.508334 8.156778 8.609988 8.11568 LOC100131434 0.634307403 0.052781704 0.037421572 10.18725026 1.874444 2.023048 2.379345 5.728038 5.509998 2.921909 TRAPPC3 0.945153478 0.043921714 0.014136101 10.18230792 5.056948 4.351315 2.165421 8.40494 7.269549 7.695565 CORIN 0.850855369 0.044490827 0.018827492 10.17653684 3.024504 2.023048 3.90836 5.728038 6.043524 7.255535 RBM17 1.009356937 0.043581008 0.011450153 10.17301144 6.45321 6.35207 6.489771 9.799885 9.623267 10.01223 KIAA1522 0.810096653 0.045243682 0.021380742 10.16769607 5.056948 5.809601 4.508334 10.252053 8.402869 7.020304 VWA5A 0.941416419 0.043921714 0.014319837 10.16548004 2.993831 3.32135 2.379345 6.339437 6.551443 5.882028 SPDEF 0.931468004 0.044025007 0.01474379 10.16227764 4.815804 4.830496 3.764125 10.106301 8.160956 6.931222 C3orf15 0.947972362 0.043900827 0.013994556 10.15823006 1.874444 2.023048 2.165421 4.894482 5.509998 5.446557 OSBPL6 0.884143586 0.044223984 0.017280027 10.15823006 1.874444 3.32135 2.165421 6.395481 5.509998 5.446557 GHR 0.861078518 0.044379352 0.018353862 10.15823006 1.874444 3.32135 2.165421 5.252045 5.509998 6.385515 MST4 0.845448845 0.044641179 0.019159578 10.15823006 1.874444 2.809601 2.165421 6.651882 5.509998 4.562324 NUP210 0.820150713 0.045095391 0.020732222 10.15823006 3.024504 2.023048 2.165421 7.450526 5.509998 4.476242 GPCRLTM7 0.797090029 0.045366463 0.022178292 10.15823006 1.874444 2.023048 2.165421 4.013424 5.509998 5.446557 GMNN 0.782729057 0.045701235 0.023124872 10.15823006 1.874444 2.809601 2.165421 9.154721 5.509998 3.630092 NSMCE2 0.744853358 0.046867572 0.02602654 10.15823006 1.874444 2.023048 2.165421 5.448591 5.509998 3.676349 RFX3 0.737897012 0.047140798 0.026560054 10.15823006 1.874444 2.023048 2.165421 5.448591 5.509998 3.630092 CEP57L1 0.668672579 0.050217419 0.032869684 10.15823006 2.201691 2.023048 2.165421 6.651882 5.509998 2.921909 RNF128 0.637784294 0.052501106 0.036957469 10.15823006 1.874444 2.023048 2.165421 5.448591 5.509998 2.921909 ANXA7 0.767689863 0.04616149 0.024304866 10.14115681 6.846868 5.487673 3.935222 9.506443 8.829823 7.668215 GAGE1 0.84753216 0.044619412 0.019051378 10.12865214 3.839948 3.872014 4.754917 6.283686 7.96603 8.095288 UPF3A 0.928195837 0.044037172 0.014909153 10.12208726 5.658609 5.148082 5.217616 8.122528 8.998044 8.745549 ASB8 0.902902451 0.044190907 0.016289895 10.12165593 3.819732 4.911517 4.754917 7.477873 7.627877 8.25089 AMIGO2 0.825190613 0.044949653 0.020417149 10.11203933 4.682076 5.148082 2.165421 6.814118 8.486085 7.291822 GPM6B 0.85601454 0.044416666 0.018551208 10.10931153 5.316227 4.351315 3.764125 8.254907 8.65384 6.722123 SIPA1L2 0.888364018 0.044203301 0.01710786 10.10751265 4.639409 2.023048 4.449894 7.976765 7.56803 6.649696 PSMA6 0.804211207 0.045327183 0.021764546 10.10063104 7.445608 6.03611 5.217616 9.539272 9.168974 9.372483 HNRNPUL2 0.850359676 0.044510429 0.01885131 10.08891485 3.839948 2.809601 2.379345 5.095353 7.174648 7.033813 LOC100128338 0.80888284 0.045247607 0.021448112 10.08891485 3.839948 4.911517 3.324375 7.25991 7.174648 6.69026 ATAD3B 0.750271393 0.046662281 0.02558081 10.08891485 3.839948 6.060401 3.90836 7.42265 7.174648 8.287303 CRYAB 0.850048872 0.044510429 0.01887853 10.08667674 7.579241 9.026217 7.107458 11.304111 12.126312 10.441837 KIAA1244 0.740999421 0.047036111 0.026299422 10.06334753 4.743564 6.605686 4.944468 8.433162 8.296229 8.074602 PALMD 0.992727384 0.043626235 0.012095951 10.06222282 1.874444 2.023048 2.165421 7.30543 5.353925 5.106393 MAP4K3 0.991703648 0.043626235 0.012143586 10.06222282 1.874444 2.023048 2.165421 6.811341 5.353925 5.106393 C2orf76 0.989217712 0.043626235 0.012198027 10.06222282 1.874444 2.023048 2.165421 6.183122 5.353925 5.106393 ANKRD32 0.987569112 0.043626235 0.012279687 10.06222282 1.874444 2.023048 2.165421 6.283686 5.353925 5.091834 CEP152 0.986564853 0.043626235 0.012313712 10.06222282 1.874444 2.023048 2.165421 5.095353 5.353925 6.051818 DOCK8 0.961441007 0.043778104 0.013309969 10.06222282 1.874444 2.023048 2.379345 6.063041 5.353925 5.106393 LRRC8D 0.956122582 0.043840967 0.013627765 10.06222282 1.874444 2.023048 2.165421 4.894482 5.353925 6.195186 FAM213B 0.95149166 0.043900827 0.01382443 10.06222282 1.874444 2.023048 2.165421 4.894482 5.353925 5.874974 CISH 0.943845056 0.043921714 0.014190541 10.06222282 1.874444 2.023048 2.165421 6.544171 5.353925 4.790662 DYNC1I1 0.943364003 0.043921714 0.014231371 10.06222282 1.874444 2.023048 2.165421 6.498222 5.353925 4.790662 STRADB 0.931553385 0.044025007 0.014736985 10.06222282 1.874444 2.023048 2.165421 4.739845 5.353925 6.195186 CCDC112 0.925893834 0.04406867 0.015071113 10.06222282 1.874444 2.023048 2.165421 5.579836 5.353925 4.790662 TUBGCP3 0.925893834 0.04406867 0.015071113 10.06222282 1.874444 2.023048 2.165421 5.579836 5.353925 4.790662 LINC00336 0.92256132 0.044091888 0.015211977 10.06222282 1.874444 2.023048 2.165421 4.718672 5.353925 5.900694 C7orf10 0.916984882 0.044110923 0.015476012 10.06222282 1.874444 2.023048 2.165421 4.739845 5.353925 5.580533 TPK1 0.891613522 0.044203301 0.016930929 10.06222282 1.874444 2.023048 2.165421 6.283686 5.353925 4.476242 DPP4 0.867734706 0.044335719 0.017997278 10.06222282 3.350997 2.023048 2.165421 6.252746 5.353925 5.634184 LOC729852 0.840876863 0.044701668 0.019426335 10.06222282 1.874444 2.023048 2.165421 6.283686 5.353925 4.146207 CD5 0.800057773 0.045343942 0.022017693 10.06222282 1.874444 2.023048 2.165421 7.582358 5.353925 3.630092 ZNF385B 0.794563604 0.04542938 0.022374957 10.06222282 1.874444 2.023048 2.165421 7.33564 5.353925 3.630092 RBM20 0.742858391 0.046915454 0.026142225 10.06222282 1.874444 2.023048 2.165421 5.579836 5.353925 3.676349 ZWINT 0.667171033 0.050335207 0.033076557 10.06222282 1.874444 2.023048 2.165421 6.244586 5.353925 2.921909 ADAMTS18 0.649185151 0.05155431 0.035183396 10.06222282 1.874444 2.023048 2.165421 2.820813 5.353925 6.129407 SAC3D1 0.643611146 0.051940048 0.036085063 10.06222282 1.874444 2.023048 2.165421 5.728038 5.353925 2.921909 GLCE 0.63303342 0.052995535 0.037682205 10.06222282 1.874444 2.023048 2.379345 5.891233 5.353925 2.921909 RNF14 0.828518624 0.044930476 0.02023001 10.06021475 4.309025 3.872014 2.995681 6.498222 8.033973 6.32627 GTF3C3 0.798490048 0.045355733 0.022095951 10.05931713 3.350997 2.809601 3.764125 5.320955 7.094585 6.69026 INTS6 0.608021132 0.055250119 0.041289554 10.05670647 4.682076 5.362142 8.487278 8.222933 9.809281 8.692228 ATP6V1C2 0.841593969 0.044701668 0.019358285 10.0534798 4.639409 3.360637 2.165421 7.144104 6.373501 6.69026 FGD6 0.9694963 0.043726704 0.013023477 10.05060281 4.309025 4.80797 4.724406 8.376156 7.598264 8.053616 SENP7 0.826233551 0.044936643 0.020332086 10.0465569 4.682076 3.872014 6.072169 7.679787 8.696398 8.010706 HMGCR 0.863597718 0.044377262 0.018191902 10.03902107 5.335413 5.340619 3.935222 8.65307 8.668166 7.327219 TMEM135 0.935774819 0.043994974 0.014528071 10.03874905 4.963444 3.360637 3.324375 6.651882 8.200916 7.873743 LOC728537 0.816318555 0.045165524 0.020951344 10.03874905 1.874444 2.023048 3.324375 6.651882 4.797798 5.426231 CHN1 0.829189809 0.044930476 0.020187819 10.03708367 4.209882 2.023048 2.165421 5.026959 7.53715 6.385515 KLF12 0.693083397 0.048944238 0.030407622 10.02807827 2.993831 2.023048 2.379345 5.705318 6.640994 3.676349 EXOSC3 0.858338174 0.044387761 0.018455257 10.01151229 1.874444 2.023048 2.995681 4.739845 6.319269 5.634184 LOC100507178 0.898151722 0.044203301 0.016572984 9.986541747 4.815804 4.389936 2.165421 6.811341 7.56803 8.135789 GNB4 0.960589767 0.043778104 0.013343995 9.985302696 3.350997 2.809601 2.995681 7.607339 6.189775 6.129407 STK38L 0.856044801 0.044416666 0.018544403 9.985302696 4.263463 2.809601 3.90836 7.42265 7.25505 6.129407 TP53BP1 0.744150043 0.046883977 0.026051718 9.985302696 5.700376 2.809601 2.995681 7.748771 7.174648 6.129407 PEX1 0.764993661 0.046181862 0.024485199 9.984179535 5.335413 3.32135 2.165421 6.498222 6.640994 7.291822 KAT2B 0.905515337 0.044173537 0.016151752 9.982413069 2.993831 3.872014 3.90836 7.504712 7.191402 6.195186 MEMO1 0.791124827 0.045499568 0.022595441 9.981432053 3.819732 2.023048 4.449894 8.801178 7.138979 5.091834 ZNF197 0.816661542 0.045162628 0.020913236 9.978698709 4.309025 2.406905 2.165421 4.739845 7.627877 7.180104 TM7SF3 0.900591868 0.044203301 0.016428037 9.969775757 5.056948 4.736586 4.724406 7.504712 8.119857 8.374509 TOMM20 0.797013061 0.045366463 0.022185097 9.969504474 6.736762 5.789702 4.508334 10.437633 9.107223 7.668215 AGPS 0.810482052 0.045237293 0.021363049 9.952935733 5.263699 3.872014 2.165421 7.918071 7.187136 6.455366 GALNT3 0.597106192 0.05661225 0.043335829 9.937051943 1.874444 4.413323 2.165421 7.726141 6.551443 2.921909 HLA-DQB1 0.839968333 0.044722631 0.01950051 9.933187 3.839948 2.023048 4.724406 7.33564 6.373501 7.152205 FOXJ3 0.758638442 0.046395081 0.024928207 9.930643744 6.554045 4.80797 4.508334 8.854326 8.119857 7.849596 EIF2AK3 0.857464483 0.044387761 0.018489282 9.92346474 5.328526 4.351315 6.012527 9.102956 8.63937 7.825039 BCL2A1 0.906945791 0.044173537 0.016056482 9.917923541 2.201691 2.023048 3.764125 7.074163 5.306419 6.455366 DEPTOR 0.609281096 0.055148494 0.041082681 9.917923541 1.874444 2.406905 3.764125 7.074163 6.549959 2.921909 FAS 0.957845691 0.043835088 0.013528411 9.917331798 4.309025 4.413323 3.90836 7.477873 8.033973 7.218312 SUPT7L 0.843134104 0.044657496 0.019239878 9.914685652 5.700376 3.770995 4.724406 8.591796 8.033973 7.395512 NKRF 0.878010959 0.044280042 0.017542021 9.911359138 3.839948 4.413323 5.225216 7.144104 8.737737 7.722406 RCBTB1 0.818691232 0.045111103 0.020811841 9.906031905 2.201691 3.32135 2.165421 7.556937 5.509998 4.790662 LOC100506874 0.858530621 0.044387761 0.018448452 9.9045413 3.024504 3.872014 4.724406 6.814118 7.25505 7.180104 HNRNPA0 0.91784539 0.044110923 0.015424294 9.901062618 7.880509 7.0089 7.825025 10.611332 10.722031 11.188093 CASP6 0.899669973 0.044203301 0.016507656 9.893210764 6.381847 5.195784 5.609945 8.616619 8.916384 9.584871 IL16 0.854285251 0.044464174 0.018649881 9.885360647 3.819732 4.830496 3.324375 6.396698 7.440337 8.135789 LAMA2 0.871603074 0.044318262 0.017800612 9.877567183 3.839948 4.736586 5.544653 7.144104 8.564762 8.678584 DOCK10 0.833718956 0.044797567 0.019768629 9.871322676 4.639409 2.809601 3.90836 6.339437 7.942653 6.924055 H1FX-AS1 0.874769867 0.044285705 0.0176754 9.869404161 5.658609 3.770995 5.389265 7.656039 8.751258 8.692228 GLUL 0.849453112 0.044521554 0.018917999 9.862635138 8.074081 7.0089 8.234655 11.853468 10.890355 10.310874 ATP7A 0.938603807 0.043986717 0.014445049 9.861219758 3.024504 2.809601 3.324375 5.891233 7.174648 6.32627 ORC1 0.752640716 0.046595104 0.025427696 9.861219758 3.024504 3.770995 2.995681 5.095353 7.094585 6.32627 ZNF107 0.818464532 0.045111103 0.020839061 9.840278913 3.350997 2.023048 4.508334 7.36523 5.857745 6.649696 COPG2 1.002842091 0.043588662 0.011748894 9.834877721 2.201691 2.023048 2.165421 5.320955 6.861783 5.426231 YY2 0.960029096 0.043802358 0.013399796 9.834877721 2.993831 2.023048 2.165421 5.320955 6.237456 6.129407 ST3GAL3 0.93402239 0.044025007 0.014628105 9.834877721 1.874444 2.023048 2.165421 5.320955 6.043524 4.790662 ALKBH2 0.889272106 0.044203301 0.017026199 9.834877721 1.874444 2.023048 2.165421 5.320955 4.539173 5.874974 SERGEF 0.867155383 0.044369384 0.018039469 9.834877721 3.839948 2.023048 2.165421 5.320955 6.794431 6.195186 SELL 0.827353131 0.044930476 0.020264035 9.834877721 1.874444 2.023048 2.165421 5.320955 5.920411 4.146207 LOC641364 0.797583876 0.045366463 0.022157877 9.834877721 2.201691 2.023048 3.764125 5.320955 5.920411 5.874974 RASL12 0.77137254 0.046066162 0.023993195 9.834877721 3.350997 2.023048 4.508334 5.320955 7.269549 6.931222 KLHL25 0.664710494 0.050400851 0.033303164 9.834877721 1.874444 2.023048 2.165421 5.320955 6.237456 2.921909 KCNA1 0.662709358 0.050529771 0.033531133 9.834877721 1.874444 2.023048 2.165421 5.320955 6.189775 2.921909 IL1RAP 0.638478293 0.052444079 0.036826812 9.834877721 1.874444 2.023048 3.764125 5.320955 7.174648 3.630092 FHL5 0.871655697 0.044318262 0.017793807 9.828419614 3.819732 2.809601 3.324375 7.30543 6.237456 6.106561 ARID1B 0.820831137 0.045095391 0.020670977 9.828222483 5.779429 5.43468 5.217616 9.07636 8.764653 7.668215 LOC100507173 0.79613624 0.045374706 0.022240898 9.826053304 4.743564 5.487673 3.90836 6.664985 8.277663 8.784285 NFX1 0.876652948 0.044280042 0.017596461 9.818598525 8.193536 8.041069 8.651386 10.852466 12.098811 11.489054 FOXN2 0.594696083 0.056878376 0.043676761 9.8178355 3.839948 3.872014 3.935222 7.167419 7.25505 4.562324 LINC00487 0.996168025 0.043626235 0.01198707 9.813846659 1.874444 2.023048 2.165421 5.252045 5.317867 5.446557 ARL15 0.985891601 0.043626235 0.012340932 9.813846659 1.874444 2.023048 2.165421 6.395481 5.317867 5.106393 C6orf162 0.98521865 0.043626235 0.012354542 9.813846659 1.874444 2.023048 2.165421 6.252746 5.317867 5.106393 C2orf63 0.984835411 0.043626235 0.012374957 9.813846659 1.874444 2.023048 2.165421 6.183122 5.317867 5.106393 ELL3 0.977770816 0.043661316 0.012626063 9.813846659 1.874444 2.023048 2.165421 5.705318 5.317867 5.091834 NAALAD2 0.94790344 0.043900827 0.014001361 9.813846659 1.874444 2.023048 2.165421 4.894482 5.317867 5.874974 PCDH9 0.941234975 0.043921714 0.014333447 9.813846659 1.874444 2.023048 2.165421 4.894482 5.317867 5.580533 SKP1P2 0.934023951 0.044025007 0.0146213 9.813846659 1.874444 2.023048 2.165421 6.063041 5.317867 4.790662 ACP6 0.897316154 0.044203301 0.016613814 9.813846659 1.874444 2.023048 2.165421 6.063041 5.317867 4.562324 LYZ 0.897169481 0.044203301 0.016638312 9.813846659 1.874444 2.023048 2.165421 6.811341 5.317867 4.476242 FBXO5 0.89499506 0.044203301 0.016767608 9.813846659 1.874444 2.023048 2.165421 6.664985 5.317867 4.476242 GLYATL2 0.874171492 0.044299467 0.017690371 9.813846659 1.874444 2.023048 2.165421 5.728038 5.317867 4.476242 RAB23 0.83710216 0.044763248 0.019644097 9.813846659 1.874444 2.023048 2.165421 6.252746 5.317867 4.146207 LRMP 0.820153681 0.045095391 0.020725417 9.813846659 1.874444 2.023048 2.165421 5.728038 5.317867 4.146207 GPR98 0.811718241 0.045218796 0.021269139 9.813846659 1.874444 2.023048 3.324375 6.857154 5.317867 4.790662 CARD16 0.775795021 0.045911642 0.023680163 9.813846659 1.874444 2.023048 2.165421 6.498222 5.317867 3.676349 HMGN5 0.766109793 0.046178907 0.024406261 9.813846659 1.874444 2.023048 2.165421 6.396698 5.317867 3.630092 PROL1 0.762818226 0.046304892 0.024695475 9.813846659 1.874444 2.023048 2.165421 9.904384 5.317867 2.921909 LOC100507062 0.761300757 0.046345155 0.024768289 9.813846659 1.874444 2.023048 2.165421 6.067497 5.317867 3.676349 GNRH1 0.761300757 0.046345155 0.024768289 9.813846659 1.874444 2.023048 2.165421 6.067497 5.317867 3.676349 LOC100506963 0.746486231 0.046811314 0.025908813 9.813846659 1.874444 2.023048 2.165421 5.705318 5.317867 3.676349 GK 0.740631282 0.047048421 0.026328003 9.813846659 1.874444 2.023048 2.165421 5.579836 5.317867 3.676349 MLF1IP 0.733703947 0.047307334 0.026809119 9.813846659 1.874444 2.023048 2.165421 5.579836 5.317867 3.630092 GLRA3 0.691483849 0.048955004 0.030565498 9.813846659 1.874444 2.023048 2.165421 6.960054 5.317867 2.921909 MAD2L1 0.676922509 0.049712169 0.031972099 9.813846659 1.874444 2.023048 2.165421 6.550689 5.317867 2.921909 CXCR6 0.674925916 0.049831488 0.032191222 9.813846659 1.874444 2.023048 2.165421 6.498222 5.317867 2.921909 ABHD10 0.670922019 0.050055202 0.032652603 9.813846659 1.874444 2.023048 2.165421 6.395481 5.317867 2.921909 TMEM206 0.670922019 0.050055202 0.032652603 9.813846659 1.874444 2.023048 2.165421 6.395481 5.317867 2.921909 DNAH14 0.670922019 0.050055202 0.032652603 9.813846659 1.874444 2.023048 2.165421 6.395481 5.317867 2.921909 LOC100507331 0.649243735 0.051527347 0.035154134 9.813846659 1.874444 2.023048 2.165421 5.891233 5.317867 2.921909 DHRS7 0.901580499 0.044203301 0.016380401 9.813480648 3.024504 3.770995 2.379345 6.651882 6.319269 6.106561 TACSTD2 0.688647036 0.049115877 0.030775774 9.80963878 5.753024 8.936581 5.702912 11.495267 9.312691 8.997112 MSTO1 0.840805747 0.044709815 0.019444029 9.79499518 1.874444 3.32135 2.165421 6.283686 6.613395 4.562324 CDKL2 0.993360304 0.043626235 0.012082341 9.791337483 1.874444 2.023048 2.165421 5.448591 5.165949 5.446557 STARD13 0.857418713 0.044387761 0.018496087 9.787161977 5.753024 4.80797 3.90836 7.748771 8.098861 8.374509 LUC7L2 0.839621195 0.044722631 0.019527731 9.780720723 6.45321 6.466258 6.326717 8.641022 9.74315 10.117111 THUMPD2 0.899802187 0.044203301 0.016489282 9.780139171 2.993831 2.023048 2.995681 6.283686 7.25505 5.091834 GBP1 0.80033406 0.045343942 0.021983668 9.776299082 4.815804 6.03611 6.369239 8.105092 9.99691 8.636861 LYRM2 0.963839153 0.043778104 0.013221504 9.77272607 5.263699 5.362142 5.018694 8.206677 8.63937 8.650903 PHTF2 0.780423963 0.045824482 0.023309289 9.768274352 3.819732 2.023048 3.935222 8.206677 7.107836 4.790662 MOAP1 0.793443674 0.04542938 0.022460701 9.767604383 1.874444 2.023048 2.995681 6.283686 5.317867 4.476242 SPIN4 0.593097125 0.057042958 0.043954406 9.767604383 1.874444 2.023048 2.995681 6.283686 5.317867 2.921909 PRTG 0.983423935 0.043626235 0.012443008 9.736285637 1.874444 2.023048 2.165421 6.183122 5.306419 5.106393 MAB21L3 0.936573225 0.043994974 0.014500851 9.736285637 1.874444 2.023048 2.165421 6.339437 5.306419 4.790662 LYRM5 0.926719544 0.044037172 0.014990813 9.736285637 1.874444 2.023048 2.165421 5.743334 5.306419 4.790662 LOC440288 0.923476732 0.044091888 0.015191562 9.736285637 1.874444 2.023048 2.165421 4.718672 5.306419 6.195186 POLR3K 0.908990215 0.044173036 0.015966655 9.736285637 1.874444 2.023048 2.165421 6.857154 5.306419 4.562324 MORN2 0.9082417 0.044173537 0.015995236 9.736285637 1.874444 2.023048 2.165421 7.877571 5.306419 4.476242 TRUB1 0.892265141 0.044203301 0.016896904 9.736285637 1.874444 2.023048 2.165421 5.891233 5.306419 4.562324 VPS8 0.887695059 0.044203301 0.017128275 9.736285637 1.874444 2.023048 2.165421 5.728038 5.306419 4.562324 BAHD1 0.868390782 0.044335719 0.017956448 9.736285637 1.874444 2.023048 3.324375 7.792994 5.306419 5.091834 IMPG2 0.864477889 0.044377262 0.018126574 9.736285637 1.874444 2.023048 2.995681 4.802615 5.306419 7.46072 ERVFRD-1 0.862997577 0.044377262 0.018253147 9.736285637 1.874444 2.023048 2.165421 4.341916 5.306419 6.129407 ERAP2 0.861717153 0.044379352 0.018306227 9.736285637 4.815804 2.023048 2.165421 7.748771 5.306419 7.352555 FAM177B 0.855920837 0.044416666 0.018558013 9.736285637 1.874444 2.023048 2.165421 4.341916 5.306419 5.874974 LYRM1 0.789328911 0.045529634 0.022676421 9.736285637 1.874444 2.023048 2.165421 7.274575 5.306419 3.630092 CSN3 0.757936957 0.046414887 0.024970398 9.736285637 1.874444 2.023048 2.165421 9.68135 5.306419 2.921909 USP6NL 0.743872 0.046889341 0.026084382 9.736285637 1.874444 2.023048 2.379345 6.339437 5.306419 3.630092 ECT2 0.721530519 0.047677157 0.027796529 9.736285637 3.819732 2.023048 3.324375 7.167419 5.306419 5.426231 GNA14 0.687648317 0.049147961 0.03085131 9.736285637 4.263463 2.023048 2.165421 5.743334 5.306419 5.580533 SDHC 0.672722794 0.049933984 0.032392651 9.736285637 4.309025 2.023048 2.165421 5.579836 5.306419 5.634184 FHIT 0.652266136 0.051304265 0.034786662 9.736285637 1.874444 2.023048 2.379345 6.395481 5.306419 2.921909 TFB2M 0.633200358 0.052977658 0.037647499 9.736285637 1.874444 2.023048 2.165421 5.579836 5.306419 2.921909 ZCWPW1 0.973382177 0.043681142 0.012831575 9.734927954 1.874444 2.023048 2.165421 5.448591 5.317867 5.106393 GZMB 0.92738906 0.044037172 0.014949983 9.734927954 1.874444 2.023048 2.165421 5.448591 4.797798 5.446557 ZMYM1 0.917315023 0.044110923 0.015448792 9.734927954 1.874444 2.023048 2.165421 5.448591 5.306419 4.790662 LIN28B 0.88049863 0.044278935 0.017422252 9.734927954 1.874444 2.023048 2.165421 5.448591 4.539173 5.426231 ATG4A 0.869448938 0.044335719 0.017902007 9.734927954 1.874444 3.32135 2.165421 5.448591 5.353925 6.455366 PPIP5K1 0.797855442 0.045355733 0.022116366 9.734927954 3.024504 4.736586 2.165421 5.448591 7.174648 7.352555 PRUNE 0.717835429 0.047825499 0.028111603 9.734927954 1.874444 2.809601 2.165421 5.448591 6.608026 3.676349 ZNF200 0.97042204 0.043726704 0.012975842 9.721212549 1.874444 2.023048 2.165421 5.095353 5.306419 5.446557 TP53TG1 0.906570934 0.044173537 0.016070092 9.721212549 2.201691 3.360637 2.165421 6.283686 6.043524 5.446557 PPFIA2 0.905115432 0.044173537 0.016185777 9.721212549 2.201691 2.023048 2.165421 4.718672 6.043524 5.446557 MYEF2 0.865948946 0.044377262 0.018099354 9.721212549 3.839948 3.32135 2.165421 8.087444 6.549959 5.446557 CCNE2 0.85004373 0.044510429 0.018885335 9.721212549 3.024504 2.023048 2.165421 5.448591 5.353925 5.446557 SULT1C2P1 0.839353283 0.044722631 0.019541341 9.721212549 1.874444 2.406905 2.165421 4.341916 6.205902 5.446557 PI15 0.721212383 0.047696784 0.027816264 9.721212549 4.263463 3.872014 2.165421 7.937902 6.043524 5.446557 KIAA1430 0.649830844 0.051486266 0.035069071 9.71596498 5.700376 3.360637 2.165421 6.814118 6.640994 6.129407 SVEP1 0.89997074 0.044203301 0.016462062 9.714846786 3.839948 3.872014 4.724406 7.074163 8.140553 7.152205 LIN52 0.866546926 0.044377262 0.018085743 9.697601849 8.379096 7.815412 7.762571 10.427146 11.656724 11.358224 ACAD9 0.809452115 0.045247607 0.021427696 9.683528031 5.304463 4.736586 3.324375 7.177844 8.579995 7.255535 SNRPD2P2 0.947059405 0.043900827 0.014035386 9.682225174 7.238972 6.35207 6.355801 9.627408 10.378653 10.166824 DIEXF 0.861349135 0.044379352 0.018347057 9.678964415 3.819732 3.32135 2.165421 6.252746 7.094585 5.874974 ADAT1 0.884199603 0.044223984 0.017273222 9.671598011 2.201691 4.389936 3.764125 7.037879 7.269549 6.455366 TRAF5 0.92370064 0.044091888 0.015177952 9.657434613 4.815804 4.389936 4.944468 8.087444 7.505595 8.32282 TMEM109 0.932206584 0.044025007 0.01471657 9.652755559 4.639409 3.770995 4.285996 7.556937 7.713236 7.255535 VPS35 0.826417753 0.044930476 0.020311671 9.652755559 5.658609 4.736586 4.285996 7.556937 8.963611 7.668215 IPW 0.867782866 0.044335719 0.017990473 9.635537548 3.024504 4.830496 4.508334 7.177844 8.098861 7.152205 HTRA4 0.882186688 0.044229452 0.017345356 9.628786419 6.554045 6.092406 7.339085 9.821399 10.183015 9.592168 ANTXR2 0.833553373 0.044797567 0.019795849 9.625651874 4.639409 3.770995 5.596986 7.037879 9.47632 7.800057 F2R 0.710179697 0.048157645 0.028771011 9.625651874 3.839948 3.770995 6.527811 7.037879 8.928336 7.352555 ZNF786 0.832395202 0.04483949 0.019876829 9.621672836 4.263463 2.406905 3.90836 5.891233 7.174648 7.428484 HERPUD1 0.899847697 0.044203301 0.016475672 9.608276134 7.155835 6.139057 6.072169 10.420113 10.008216 9.08248 SPIN1 0.911994826 0.044142622 0.015767948 9.605772857 6.054828 4.750708 5.225216 8.014609 9.20872 9.123341 CDIPT 0.863469387 0.044377262 0.018198707 9.605128152 6.267718 3.872014 5.389265 8.65307 8.97518 8.175185 PDS5B 0.815278848 0.045173526 0.021032324 9.587704469 5.316227 3.770995 4.754917 7.531061 8.986657 7.03218 C8orf58 0.958867918 0.043826549 0.013456278 9.585208521 1.874444 2.023048 2.165421 5.026959 5.317867 5.426231 MOSPD1 0.905387624 0.044173537 0.016158557 9.585208521 2.201691 2.023048 2.165421 7.25991 4.608763 5.426231 LOC100289178 0.899914037 0.044203301 0.016468867 9.585208521 1.874444 2.406905 2.165421 5.891233 4.797798 5.426231 TXNDC16 0.897450994 0.044203301 0.016600204 9.585208521 3.024504 2.809601 2.165421 6.498222 5.857745 5.426231 HEATR5B 0.881113588 0.044271261 0.017396393 9.585208521 3.024504 3.360637 2.165421 6.244586 6.861783 5.426231 RNF214 0.870006405 0.044335719 0.017867982 9.585208521 1.874444 2.406905 2.165421 6.283686 4.539173 5.426231 CWC22 0.837181983 0.044763248 0.019637292 9.585208521 1.874444 3.360637 2.165421 6.063041 5.306419 5.426231 ENPP4 0.808617938 0.045247607 0.021468527 9.585208521 3.350997 2.023048 2.165421 7.109557 4.797798 5.426231 GMCL1P1 0.795683277 0.04540117 0.022317795 9.585208521 3.839948 2.023048 2.165421 6.811341 5.306419 5.426231 KIAA0317 0.726474512 0.047532676 0.027403879 9.585208521 2.993831 4.830496 2.165421 6.954147 6.640994 5.426231 TRIM7 0.654723789 0.051064299 0.034427356 9.585208521 1.874444 2.023048 2.165421 5.320955 3.134528 5.426231 TMC7 0.838074609 0.044745607 0.019601225 9.574490581 9.354026 8.07747 7.180931 11.036191 12.15075 11.336666 SNX7 0.973833177 0.043681142 0.012790745 9.574397339 3.024504 3.32135 2.379345 6.283686 6.549959 6.195186 ACSL3 0.816843554 0.045162628 0.020906431 9.572986163 4.309025 6.060401 5.018694 9.4454 8.277663 7.46072 KIF3A 0.842455419 0.044657496 0.019287513 9.572626689 2.993831 3.360637 4.944468 6.252746 7.292524 7.825039 INSIG2 0.630615361 0.053156193 0.037966655 9.565033307 5.753024 3.360637 2.379345 6.252746 6.640994 6.618407 ETNK2 0.896344059 0.044203301 0.016679143 9.560125365 3.350997 3.32135 2.379345 6.244586 6.608026 5.900694 MAP1LC3C 0.726242372 0.047543032 0.02741953 9.554503585 2.993831 3.360637 3.935222 4.802615 7.191402 7.152205 SLC30A8 0.881230913 0.044271261 0.017389588 9.554494328 1.874444 2.406905 3.764125 5.095353 6.613395 7.020304 LNX2 0.896223803 0.044203301 0.016692753 9.545622161 3.350997 3.360637 2.379345 6.954147 6.551443 5.634184 EDC3 0.832364969 0.04483949 0.019890439 9.545622161 2.993831 4.413323 2.379345 6.954147 7.191402 5.634184 PRCC 0.755454341 0.046505334 0.02520313 9.545622161 3.839948 3.872014 2.379345 6.067497 7.292524 5.634184 TMEM106B 0.765043724 0.046178907 0.024467506 9.526289835 4.743564 3.872014 3.935222 8.105092 7.187136 6.129407 SRSF8 0.905270347 0.044173537 0.016172167 9.525246799 6.186289 2.809601 5.389265 8.641022 8.332658 8.997112 TAC1 0.822497754 0.045019115 0.020575706 9.518638124 2.993831 2.406905 3.90836 6.244586 8.904331 5.106393 BRWD3 0.815048871 0.045182971 0.021065669 9.509104506 2.993831 3.770995 3.935222 5.579836 7.656894 7.020304 C14or129 0.93107695 0.044025007 0.014764206 9.50643849 2.201691 2.406905 2.995681 6.244586 5.857745 5.446557 TUT1 0.856500495 0.044407381 0.018532154 9.496456142 3.839948 3.360637 2.165421 5.705318 6.608026 6.942983 SCCPDH 0.788738046 0.045550411 0.022722014 9.496456142 4.815804 3.360637 2.379345 7.477873 6.608026 6.051818 BCL10 0.752473999 0.046595104 0.025441307 9.496456142 5.982974 3.360637 2.379345 9.179923 6.608026 6.385515 PEX3 0.923709358 0.044091888 0.015171147 9.493239106 2.201691 3.360637 2.379345 5.448591 6.373501 6.385515 TMTC4 0.883980315 0.044223984 0.017286832 9.493239106 2.201691 2.406905 3.324375 5.448591 5.936219 6.195186 ZDHHC11 0.739411847 0.047109709 0.026422593 9.49008989 6.186289 4.736586 5.544653 7.144104 8.791075 9.50208 ZNF593 0.850988388 0.044490827 0.018820687 9.485152665 5.056948 5.43468 4.449894 9.229044 7.740604 7.695565 LOC441666 0.97562023 0.043661316 0.012728139 9.479864214 2.201691 2.023048 2.379345 5.252045 7.066159 5.446557 NCK1 0.864860262 0.044377262 0.018112964 9.479864214 2.201691 2.809601 3.764125 6.664985 6.608026 5.446557 AZIN1 0.910682111 0.044159136 0.015872065 9.478210162 6.143785 6.049721 5.571599 9.863488 9.294336 8.564524 EXOG 0.776869037 0.045858868 0.023545424 9.473157121 5.304463 3.32135 3.90836 6.664985 7.819723 7.152205 HERC3 0.910576228 0.044159136 0.015885675 9.459568595 2.993831 3.32135 2.995681 6.857154 6.237456 5.874974 SLC37A2 0.771108571 0.04607418 0.02402654 9.459568595 2.993831 3.360637 2.995681 4.894482 6.237456 7.36177 PDGFC 0.568154693 0.060662455 0.049376659 9.459568595 2.993831 3.872014 2.995681 7.504712 6.237456 3.630092 SAA2 0.87573713 0.044285705 0.017654985 9.448753911 4.815804 4.351315 3.90836 7.679787 8.055928 6.931222 VBP1 0.759208297 0.046382879 0.024899626 9.436994364 4.263463 4.750708 5.389265 8.864724 7.989035 6.587378 DEM1 0.895866201 0.044203301 0.016706363 9.424272208 3.350997 2.406905 2.165421 5.252045 6.205902 6.587378 PRPF39 0.846324796 0.044634679 0.01912147 9.423837309 2.993831 3.32135 5.596986 8.833301 8.579995 5.874974 PANK1 0.856876757 0.044387761 0.018502892 9.420784716 7.595107 6.270596 7.381261 9.506443 10.535355 11.106371 GCC2 0.918854585 0.044110923 0.015369854 9.420113192 3.839948 2.023048 3.90836 7.144104 6.640994 6.649696 OPHN1 0.940384211 0.043921714 0.014347057 9.408222924 3.024504 2.809601 2.165421 5.705318 6.043524 6.195186 NCKAP1L 0.909563941 0.044173036 0.01593263 9.395368165 1.874444 2.406905 2.379345 5.743334 5.317867 5.106393 LRRC28 0.895000367 0.044203301 0.016760803 9.395368165 1.874444 2.809601 2.165421 6.252746 5.353925 5.106393 C9orf103 0.868352765 0.044335719 0.017963253 9.395368165 1.874444 2.023048 3.90836 6.960054 6.373501 5.106393 ANK3 0.830502516 0.044867325 0.020032664 9.395368165 1.874444 3.770995 2.165421 6.183122 6.319269 5.106393 PGBD2 0.818323631 0.045123634 0.02085199 9.395368165 1.874444 2.406905 3.324375 5.705318 5.920411 5.106393 ZNF853 0.809455894 0.045247607 0.021420891 9.395368165 1.874444 2.406905 3.764125 6.544171 5.936219 5.106393 XDH 0.722780918 0.04762218 0.027667234 9.395368165 1.874444 4.351315 2.379345 6.395481 5.936219 5.106393 NDUFC2 0.890802577 0.044203301 0.016958149 9.380428912 6.143785 5.362142 6.072169 8.591796 9.138429 9.397686 ENTPD1 0.723807981 0.047585406 0.027571283 9.376899158 5.335413 5.297868 5.544653 6.960054 9.042712 8.564524 DKFZp686K1684 0.976441613 0.043661316 0.012666894 9.376158358 1.874444 2.023048 2.165421 5.252045 6.608026 5.091834 DNAH8 0.972720601 0.043681142 0.012858796 9.376158358 1.874444 2.023048 2.165421 5.252045 5.936219 5.091834 HLTF 0.931103178 0.044025007 0.0147574 9.376158358 1.874444 2.023048 2.165421 5.252045 6.373501 4.790662 GLDN 0.903950697 0.044173537 0.016233413 9.376158358 1.874444 2.023048 2.165421 5.252045 4.608763 6.385515 PDZD2 0.902453037 0.044190907 0.016330725 9.376158358 1.874444 2.023048 2.165421 5.252045 6.774676 4.562324 RHOBTB2 0.888507122 0.044203301 0.01709425 9.376158358 1.874444 2.023048 2.165421 5.252045 5.936219 4.562324 TRDN 0.887342981 0.044203301 0.017141885 9.376158358 1.874444 2.023048 2.165421 5.252045 4.539173 6.051818 C15orf38 0.801224952 0.045343936 0.02193195 9.376158358 1.874444 2.023048 2.165421 5.252045 4.131418 5.446557 ODZ1 0.767738664 0.04616149 0.02428445 9.376158358 1.874444 2.023048 2.165421 5.252045 6.613395 3.630092 LOC729176 0.723392766 0.04762218 0.027626404 9.376158358 1.874444 2.023048 2.165421 5.252045 3.571326 5.634184 LRRIQ1 0.651726569 0.051344565 0.034858796 9.376158358 1.874444 2.023048 2.165421 5.252045 3.134528 5.446557 ENPP5 0.646385108 0.051758104 0.035680163 9.376158358 1.874444 2.023048 2.165421 5.252045 5.920411 2.921909 AADAT 0.687584579 0.049147961 0.030858115 9.36150775 3.839948 3.360637 2.165421 4.341916 7.138979 6.587378 EIF3I 0.869232158 0.044335719 0.017908813 9.359758546 8.17254 6.931478 7.538623 10.157949 10.850079 11.356082 UAP1 0.873399131 0.044299467 0.017724396 9.357023515 5.897292 5.362142 6.670675 8.935488 9.383862 9.123341 C11orf10 0.900215093 0.044203301 0.016448452 9.354444804 7.410173 6.702075 6.450701 10.635825 9.884832 9.814317 ALDH8A1 0.90951017 0.044173036 0.01594624 9.336106901 3.819732 3.32135 3.764125 6.544171 7.473335 6.618407 KAT8 0.897748399 0.044203301 0.016579789 9.331026833 4.309025 2.809601 3.764125 7.531061 6.861783 6.587378 TRMT112 0.903638141 0.044173537 0.016260633 9.329124799 6.898923 6.184248 5.592916 9.204692 10.058027 9.40599 LDHA 0.7850247 0.045655746 0.022978564 9.327175138 8.224469 8.124619 7.082111 11.445909 10.430001 10.354432 LOC285758 0.958240786 0.043826549 0.013497108 9.323744973 1.874444 2.023048 2.165421 5.095353 6.608026 5.106393 FMO2 0.849129284 0.044539625 0.018939775 9.323744973 1.874444 2.023048 4.754917 5.095353 7.656894 7.255535 CLIC5 0.814651902 0.045212649 0.021124192 9.323744973 1.874444 2.406905 3.935222 5.095353 6.189775 6.73963 MAMDC2 0.767188288 0.04617033 0.024353862 9.323744973 1.874444 3.32135 4.449894 5.095353 7.292524 7.03218 HAS2 0.695563313 0.048858998 0.030246342 9.323744973 1.874444 2.809601 5.018694 5.095353 6.613395 7.03218 C6orf130 0.659554816 0.050730781 0.03385165 9.323744973 1.874444 2.023048 4.449894 5.095353 5.936219 5.426231 ODZ2 0.63058346 0.053156193 0.037984348 9.323744973 1.874444 4.736586 2.165421 5.095353 6.189775 5.426231 C16orf87 0.846783268 0.044634679 0.01908064 9.31839741 3.024504 2.023048 2.165421 6.244586 6.237456 4.562324 CELSR2 0.82306347 0.045019115 0.020534876 9.316556204 2.993831 2.406905 3.324375 6.544171 6.373501 5.091834 GTF2H2C 0.74921211 0.046728791 0.025712827 9.316556204 4.309025 3.32135 3.324375 6.544171 5.509998 7.849596 RSU1 0.94616863 0.043900827 0.014089826 9.312944397 5.744513 6.072636 4.508334 8.745998 9.179013 8.96375 RPLP2 0.93637201 0.043994974 0.014514461 9.311680707 11.957438 12.145455 12.163832 15.364497 14.963896 15.494123 ASZ1 0.758179627 0.046410533 0.024957469 9.309957171 5.982974 5.148082 5.571599 7.36523 8.87992 9.201749 HCP5 0.967961818 0.043738451 0.013054781 9.301029682 1.874444 2.023048 2.165421 7.25991 5.165949 5.091834 TMEM56 0.96650004 0.043778104 0.013133038 9.301029682 1.874444 2.023048 2.165421 5.320955 5.353925 5.091834 GATM 0.96634556 0.043778104 0.013139843 9.301029682 1.874444 2.023048 2.165421 6.811341 5.165949 5.091834 KIAA1841 0.963340515 0.043778104 0.013248724 9.301029682 1.874444 2.023048 2.165421 6.183122 5.165949 5.091834 APLF 0.941334144 0.043921714 0.014326642 9.301029682 1.874444 2.406905 2.165421 5.320955 6.205902 5.091834 RFK 0.863101924 0.044377262 0.018246342 9.301029682 1.874444 3.32135 2.165421 8.014609 5.306419 5.091834 LOC286189 0.846946602 0.044634679 0.019073835 9.301029682 1.874444 2.023048 2.995681 5.448591 5.509998 5.091834 HHLA3 0.802955265 0.045338539 0.021862538 9.301029682 1.874444 2.023048 3.90836 6.396698 5.920411 5.091834 NUDT16L1 0.779996533 0.045824482 0.023322899 9.301029682 1.874444 2.406905 3.935222 7.33564 5.509998 5.091834 NOS1AP 0.699884747 0.048716465 0.029867302 9.301029682 1.874444 2.406905 4.285996 5.728038 6.205902 5.091834 ARFGEF1 0.918679425 0.044110923 0.015383464 9.296676091 3.839948 4.351315 3.935222 7.177844 7.56803 6.942983 ATG13 0.757486548 0.046414887 0.024997618 9.295211201 6.554045 3.32135 4.944468 7.792994 8.160956 8.357484 MGEA5 0.935566485 0.043994974 0.014548486 9.289062291 6.417969 4.389936 6.704285 9.633502 9.853832 9.201749 RB1 0.880285647 0.044278935 0.017435863 9.26679867 2.993831 2.023048 2.165421 5.579836 6.205902 5.091834 CRIP2 0.897537899 0.044203301 0.016586594 9.261728195 6.48761 6.821329 6.410545 9.698891 9.198885 11.006149 BCCIP 0.640164642 0.052240009 0.036551208 9.260646112 4.639409 5.43468 4.754917 9.012327 7.96603 5.882028 MIOS 0.729896664 0.047394039 0.027122831 9.254529613 4.963444 4.389936 3.90836 8.173604 7.656894 6.051818 KLHL18 0.897376279 0.044203301 0.016607009 9.246341455 3.350997 3.770995 3.935222 7.144104 6.613395 6.649696 CTSL2 0.841410508 0.044701668 0.0193787 9.246341455 1.874444 4.736586 3.935222 7.144104 6.551443 7.218312 FBLIM1 0.888553471 0.044203301 0.017087445 9.214815232 5.700376 6.228068 5.609945 8.822673 8.904331 8.941073 WDSUB1 0.800227728 0.045343942 0.021990473 9.198219341 2.993831 2.023048 2.165421 5.448591 4.608763 6.195186 KANSL2 0.911360788 0.044142622 0.015801973 9.197215391 2.201691 4.413323 3.90836 7.109557 7.406567 6.73963 ZNF827 0.926309187 0.04406867 0.015033685 9.197160696 1.874444 2.023048 2.379345 5.095353 5.165949 5.580533 PPCDC 0.91181476 0.044142622 0.015781558 9.197160696 1.874444 2.023048 2.379345 4.894482 5.317867 5.580533 C8orf77 0.771528202 0.046066162 0.023979585 9.19322946 3.819732 3.872014 2.165421 5.026959 7.440337 7.020304 ST20 0.845473246 0.044641179 0.019152773 9.192713565 1.874444 3.360637 2.379345 5.579836 5.317867 6.195186 LOC100129250 0.614352157 0.054543342 0.040267438 9.192713565 1.874444 2.023048 2.379345 5.579836 5.306419 2.921909 NXT2 0.807721254 0.045265409 0.021512079 9.192428236 3.350997 3.770995 2.165421 5.448591 6.551443 6.587378 LRBA 0.795682203 0.04540117 0.0223246 9.192428236 3.350997 2.406905 2.379345 4.739845 6.551443 6.051818 PIGC 0.649384165 0.051527347 0.035133719 9.192428236 3.350997 3.360637 2.165421 7.177844 6.551443 3.676349 ZFYVE28 0.582195638 0.05842099 0.046208915 9.186251256 2.201691 2.023048 3.90836 2.820813 7.107836 6.385515 FAF2 0.855808527 0.044416666 0.018564818 9.183783341 4.743564 3.360637 2.995681 7.243046 7.942653 6.129407 KLHL12 0.866573272 0.044377262 0.018078938 9.182980724 3.350997 2.023048 2.165421 4.894482 6.549959 6.195186 FAH 0.754377791 0.04655221 0.025307928 9.182980724 3.350997 3.360637 2.165421 7.243046 6.549959 4.476242 TMEM192 0.670947347 0.050055202 0.032638993 9.17934421 5.335413 4.389936 4.508334 5.728038 8.533804 8.407967 SCN3B 0.867006862 0.044369384 0.018059884 9.16379046 2.993831 2.023048 2.165421 5.095353 6.189775 5.446557 MAML2 0.842487463 0.044657496 0.019280708 9.16379046 2.993831 2.023048 2.995681 4.894482 6.189775 6.649696 C7orf25 0.830689539 0.044867325 0.020019054 9.16379046 2.993831 2.023048 3.324375 6.544171 6.189775 5.106393 SMARCA1 0.934715878 0.04402131 0.014602246 9.162154918 4.309025 4.413323 4.754917 7.504712 8.502167 7.523109 SLC35B2 0.86431263 0.044377262 0.018144267 9.159611284 4.209882 3.770995 4.944468 8.139755 7.505595 6.924055 SLC12A6 0.894592532 0.044203301 0.016801633 9.156625193 5.316227 3.770995 4.508334 7.70315 7.627877 8.232333 ZNF281 0.872608268 0.044299467 0.017751616 9.153591896 4.743564 2.809601 3.764125 7.937902 6.861783 6.73963 SAMD9L 0.903736525 0.044173537 0.016247023 9.15204562 1.874444 2.809601 2.995681 5.728038 6.189775 5.580533 MXRA5 0.890361021 0.044203301 0.016978564 9.126440744 3.839948 3.360637 4.724406 6.550689 10.329923 7.020304 TRAK2 0.749359631 0.046728791 0.025685607 9.126440744 5.304463 3.360637 2.995681 6.550689 7.793829 6.455366 SEC62 0.905812398 0.044173537 0.016110922 9.122733769 7.759008 6.877454 6.861515 10.948474 9.968249 10.469833 ZNF839 0.961888108 0.043778104 0.013296359 9.116652051 2.201691 2.023048 2.165421 6.857154 5.353925 5.091834 ERBB4 0.791671426 0.045499568 0.022575026 9.116652051 1.874444 3.32135 2.165421 7.748771 5.353925 4.476242 CYP2U1 0.755413416 0.046505334 0.025209935 9.116652051 3.024504 3.770995 2.165421 7.25991 5.353925 5.426231 GABRB2 0.617802715 0.054209095 0.039789044 9.116652051 1.874444 2.023048 2.165421 5.252045 5.353925 2.921909 FHOD1 0.872688847 0.044299467 0.017738006 9.109287856 5.263699 2.406905 4.285996 7.42265 7.473335 7.722406 C16orf48 0.759390888 0.046382879 0.024886016 9.108611025 3.819732 2.406905 4.508334 6.339437 5.920411 7.695565 ATAD1 0.734743702 0.04729774 0.026744471 9.108611025 6.52121 4.830496 4.508334 8.616619 8.160956 7.695565 BTG2 0.928118321 0.044037172 0.014915958 9.104158558 8.062715 7.631788 8.223105 12.3874 10.818314 11.126612 AP1AR 0.85480432 0.044445393 0.018604287 9.082898197 3.839948 3.770995 4.724406 6.954147 7.269549 7.218312 KRBOX1 0.818567324 0.045111103 0.020832256 9.082898197 2.201691 3.770995 2.165421 6.954147 5.857745 5.106393 GTF2H2 0.807513546 0.045272487 0.021522967 9.061379311 6.306772 5.661685 6.031658 8.173604 9.237827 9.486503 PLA2G2D 0.830735558 0.044867325 0.020012249 9.050462554 9.504433 9.168002 9.143179 11.58762 12.480008 12.682424 ABI3BP 0.83037273 0.044867325 0.020066689 9.043438974 4.682076 3.32135 4.724406 6.498222 8.453372 7.640338 ZFAND1 0.831590798 0.044867325 0.019964614 9.032956932 4.639409 3.872014 3.324375 7.814607 7.187136 6.32627 HECTD3 0.889990273 0.044203301 0.016998979 9.023132952 3.024504 2.406905 2.379345 5.448591 6.319269 5.580533 CCDC88C 0.638459655 0.052444079 0.036833617 9.023132952 2.993831 2.406905 2.165421 6.183122 3.571326 5.580533 CCNT2 0.694763209 0.048858998 0.030280367 9.019230124 4.309025 4.389936 5.217616 8.39062 8.160956 5.874974 SLC35A3 0.830125225 0.044892504 0.020098673 9.01876997 1.874444 2.406905 2.165421 5.579836 5.353925 4.476242 PPP1R9A 0.892281855 0.044203301 0.016890099 9.016793543 4.682076 4.389936 3.935222 7.631894 7.107836 7.668215 PGR 0.860443755 0.044379352 0.018374277 9.016793543 3.350997 4.351315 3.935222 6.544171 7.107836 7.255535 TMEM183B 0.888395767 0.044203301 0.017101055 9.012880998 3.350997 3.770995 4.285996 6.651882 7.292524 6.942983 TGOLN2 0.783831946 0.045695042 0.023050698 9.011667533 6.054828 4.351315 5.596986 9.438455 8.402869 7.523109 LOC100302401 0.816346166 0.045165524 0.020944539 9.004719181 3.024504 2.023048 3.324375 4.802615 7.292524 6.195186 TCEB2 0.912481384 0.044142622 0.015747533 8.997870117 6.792865 6.572071 4.724406 9.16317 9.962448 9.710869 VIPR1 0.702777863 0.048528882 0.029591017 8.994451756 1.874444 4.413323 3.764125 7.582358 5.936219 5.446557 ZC3H7A 0.83647507 0.044768725 0.019668595 8.989135901 4.639409 4.750708 2.165421 6.960054 7.91889 7.033813 PNPT1 0.756468996 0.046450467 0.025104457 8.982980273 5.304463 6.762934 5.544653 8.711848 8.764653 8.503924 ST13P4 0.868567126 0.044335719 0.017942838 8.975030465 7.392123 6.983552 6.861515 10.149468 10.739097 9.67008 SNX14 0.868446922 0.044335719 0.017949643 8.97101457 3.024504 2.023048 2.165421 6.067497 6.189775 4.790662 MLLT10 0.787733481 0.045562713 0.022764206 8.9494534 5.335413 3.872014 3.90836 7.957464 7.094585 7.033813 FDPSL2A 0.728303007 0.047454185 0.027253488 8.94071197 5.304463 5.43468 4.449894 6.664985 8.59507 8.519314 LOC145820 0.820398817 0.045095391 0.020691392 8.939703918 2.201691 3.770995 3.90836 7.877571 5.306419 6.931222 STIL 0.790244186 0.045525452 0.022651922 8.939703918 2.993831 3.770995 2.165421 5.095353 6.237456 6.931222 DDX19B 0.952674875 0.043882243 0.013764546 8.91067111 1.874444 2.023048 2.165421 5.320955 5.165949 5.106393 ZNF862 0.892767201 0.044203301 0.016869684 8.91067111 3.024504 2.809601 2.165421 5.320955 6.794431 5.874974 ATG7 0.780363381 0.045824482 0.023316094 8.91067111 4.209882 2.809601 2.165421 5.320955 6.861783 6.32627 LOC283914 0.683028088 0.049394421 0.031348078 8.903302375 4.309025 3.872014 4.285996 5.448591 7.440337 7.668215 TTC17 0.871808297 0.044318262 0.017787002 8.900755449 4.743564 4.413323 3.764125 6.814118 7.845161 7.897492 ACOT2 0.935387147 0.043994974 0.014565498 8.892043921 1.874444 2.023048 2.165421 5.026959 5.353925 5.106393 FASTKD3 0.935387147 0.043994974 0.014565498 8.892043921 1.874444 2.023048 2.165421 5.026959 5.353925 5.106393 GNPAT 0.842973479 0.044657496 0.019246683 8.892043921 1.874444 3.32135 2.379345 5.026959 6.237456 5.882028 TDRD3 0.811981162 0.045218796 0.021235114 8.892043921 1.874444 3.770995 2.379345 5.026959 6.205902 6.385515 MB21D1 0.752793235 0.046592834 0.025416808 8.892043921 1.874444 2.023048 3.764125 5.026959 5.353925 6.129407 RPL23AP64 0.960632025 0.043778104 0.013330384 8.891616387 2.201691 2.023048 2.165421 7.109557 5.317867 5.106393 ADAMTS6 0.919056794 0.044110923 0.015363049 8.891616387 1.874444 2.406905 2.165421 5.095353 5.317867 5.446557 SCRN3 0.872302172 0.044299467 0.017772031 8.891616387 3.024504 2.406905 2.165421 6.395481 5.317867 5.446557 RFTN1 0.826832431 0.044930476 0.020291256 8.891616387 3.350997 2.406905 2.165421 5.728038 5.317867 5.874974 LOC145663 0.723145969 0.04762218 0.027640014 8.891616387 1.874444 2.023048 2.165421 5.252045 5.317867 3.676349 ZRANB2-AS1 0.716166872 0.04786157 0.028245662 8.891616387 1.874444 2.023048 2.165421 5.252045 5.317867 3.630092 EPB41L4B 0.619721719 0.054008689 0.039501871 8.891616387 3.024504 2.023048 2.165421 7.504712 5.317867 2.921909 MDGA2 0.614045652 0.054587228 0.040317115 8.891616387 2.201691 2.023048 2.165421 5.705318 5.317867 2.921909 PRSS16 0.607696045 0.05527432 0.041349439 8.891616387 1.874444 2.406905 2.165421 5.705318 5.317867 2.921909 LOC729013 0.600357523 0.056340121 0.042788704 8.891616387 2.201691 2.023048 2.165421 5.448591 5.317867 2.921909 STAU2 0.800036913 0.045343942 0.022024498 8.890313126 2.201691 2.406905 3.935222 6.651882 5.353925 5.882028 PPPDE1 0.871203173 0.044325295 0.017818306 8.880392409 4.263463 3.360637 3.324375 7.144104 7.414086 6.129407 GNAI2 0.906370477 0.044173537 0.016083702 8.868460971 7.427999 6.270596 7.180931 10.240121 9.927144 10.576683 NR2C1 0.824034027 0.044965427 0.020458659 8.859499576 3.350997 4.351315 4.508334 6.498222 7.870158 7.152205 CIAPIN1 0.720561139 0.047703746 0.027869343 8.859499576 3.350997 3.770995 3.324375 6.498222 7.174648 5.106393 EEF1A1 0.923960992 0.044091888 0.015164342 8.859041915 12.260147 11.991816 12.5153 15.659795 15.662451 15.077998 DIS3 0.823425764 0.045005314 0.020512419 8.853633233 5.056948 4.830496 6.031658 7.976765 8.63937 8.305171 PDK4 0.713517357 0.047910176 0.028412385 8.851123148 8.965816 6.732825 6.737132 10.9362 9.878685 10.256805 ELK4 0.916072017 0.044110923 0.015523647 8.843301973 7.09018 6.605686 6.769247 9.750272 10.539257 9.83906 CDH16 0.945321789 0.043921714 0.014129296 8.832988699 1.874444 2.023048 2.165421 4.894482 5.165949 7.774634 ARV1 0.920116207 0.044110923 0.015335829 8.832988699 1.874444 2.023048 2.165421 6.244586 5.165949 4.790662 LDHAL6A 0.91072405 0.044159136 0.01586526 8.832988699 1.874444 2.023048 2.379345 5.252045 5.165949 5.106393 LINC00410 0.850522752 0.044504737 0.018840422 8.832988699 1.874444 2.023048 2.165421 4.341916 5.165949 6.129407 LINC00340 0.826277834 0.044930476 0.020321878 8.832988699 1.874444 2.023048 2.165421 6.339437 5.165949 4.146207 PCCB 0.826277834 0.044930476 0.020321878 8.832988699 1.874444 2.023048 2.165421 6.339437 5.165949 4.146207 DENND2D 0.815702996 0.045173526 0.021011909 8.832988699 1.874444 2.023048 2.995681 7.70315 5.165949 4.476242 ADAM28 0.781131312 0.045799831 0.023266417 8.832988699 1.874444 2.023048 2.379345 7.976765 5.165949 3.676349 CCDC99 0.757356082 0.046414887 0.025011228 8.832988699 1.874444 2.023048 2.165421 6.283686 5.165949 3.676349 PPIL1 0.736960252 0.047171086 0.026606329 8.832988699 1.874444 2.023048 2.165421 5.891233 5.165949 3.630092 KIF27 0.723865581 0.047585406 0.027564478 8.832988699 1.874444 2.023048 2.165421 5.579836 5.165949 3.630092 C8orf85 0.652044561 0.051316368 0.034823409 8.832988699 1.874444 2.023048 2.165421 6.183122 5.165949 2.921909 ARHGAP36 0.647187024 0.05166843 0.035522967 8.832988699 1.874444 2.023048 2.165421 6.067497 5.165949 2.921909 C11orf74 0.64699619 0.05169609 0.035571963 8.832988699 1.874444 2.023048 2.165421 6.063041 5.165949 2.921909 PCLO 0.632545511 0.053037004 0.037753658 8.832988699 1.874444 2.023048 2.165421 5.743334 5.165949 2.921909 PMCHL2 0.622928374 0.053781042 0.039043892 8.832988699 4.639409 2.023048 2.165421 5.448591 5.165949 5.882028 LMF1 0.68397964 0.049369649 0.031299081 8.830456312 5.263699 2.023048 4.285996 5.448591 7.793829 7.428484 SPA17 0.954944142 0.043840967 0.01368901 8.821343956 2.201691 2.023048 2.165421 6.252746 5.306419 5.106393 BATF3 0.900046151 0.044203301 0.016455257 8.821343956 1.874444 2.809601 2.165421 4.894482 5.306419 8.758577 TRUB2 0.879447847 0.044278935 0.017469888 8.821343956 1.874444 2.406905 2.165421 4.739845 5.306419 5.874974 GINS2 0.831970289 0.044855041 0.019911535 8.821343956 1.874444 2.406905 2.165421 5.705318 5.306419 4.476242 SULT1E1 0.824556675 0.044949653 0.020430759 8.821343956 3.024504 2.023048 2.165421 5.252045 5.306419 5.426231 ZNF23 0.795839139 0.045374706 0.022274923 8.821343956 2.993831 2.023048 2.165421 6.651882 5.306419 4.562324 CASQ2 0.763890936 0.046215863 0.024560735 8.821343956 3.819732 2.023048 2.165421 5.026959 5.306419 7.020304 CCDC88B 0.676254139 0.049726364 0.032036747 8.821343956 2.201691 2.023048 2.165421 7.25991 5.306419 2.921909 C7orf46 0.626663461 0.053489675 0.038566859 8.821343956 2.993831 2.023048 2.165421 7.656039 5.306419 2.921909 UTP15 0.860246619 0.044379352 0.018387887 8.808773156 3.839948 2.809601 3.935222 7.074163 6.794431 6.195186 RPS27L 0.759054746 0.046382879 0.024906431 8.801809402 8.085359 6.537655 6.054038 9.675455 10.347834 9.517491 LOC100216546 0.909823847 0.044159136 0.015912896 8.800496432 1.874444 3.360637 3.324375 6.498222 6.205902 6.051818 VSIG10 0.835023256 0.044793607 0.01971555 8.788253044 2.993831 2.809601 2.995681 5.252045 6.373501 6.129407 TSC22D2 0.913599984 0.044110923 0.015680163 8.772096566 5.316227 5.789702 6.056062 8.864724 9.188984 8.678584 CTPS2 0.929534814 0.044037172 0.014847907 8.769315211 4.639409 4.80797 4.449894 7.582358 8.63937 7.668215 ALS2CR8 0.702824226 0.04852027 0.029578088 8.758313564 3.350997 4.750708 2.379345 6.544171 5.509998 6.942983 ZMYM2 0.819543147 0.045111103 0.020771011 8.746364803 5.335413 4.80797 5.571599 8.700282 8.624754 7.46072 C1orf131 0.657940159 0.050866557 0.03405376 8.733852469 3.350997 2.809601 2.165421 7.25991 5.936219 3.676349 ZNF37BP 0.840152947 0.044722631 0.019466485 8.725933753 5.856559 6.792427 7.204614 9.111713 10.329923 9.899123 USP46 0.859986057 0.044379352 0.018401497 8.716974692 4.209882 4.413323 2.165421 6.544171 7.53715 7.03218 SPTY2D1 0.903991892 0.044173537 0.016226608 8.70925824 5.753024 5.148082 5.596986 8.270632 8.63937 9.294121 AQP1 0.834495589 0.044793607 0.019749575 8.698428211 3.819732 5.661685 4.724406 6.814118 7.845161 11.2096 FGL2 0.891629786 0.044203301 0.016917319 8.689756396 5.658609 4.830496 4.944468 7.835902 8.777924 8.472642 ETV1 0.940220965 0.043921714 0.014353862 8.689446069 2.201691 2.023048 2.379345 5.320955 7.269549 5.091834 TSPAN7 0.727993136 0.047463619 0.027266417 8.689446069 2.201691 3.872014 5.018694 5.320955 6.613395 9.372483 NECAB1 0.727040953 0.047516329 0.027371895 8.689446069 2.201691 2.406905 2.165421 5.320955 6.78473 3.676349 WDR66 0.876372325 0.044280042 0.017603266 8.670864417 2.201691 2.023048 2.379345 4.739845 5.317867 6.129407 TMPRSS11BNL 0.83696069 0.044768725 0.019654985 8.670864417 2.201691 2.809601 2.165421 4.802615 5.317867 6.618407 MSRB3 0.909700309 0.044159136 0.015919701 8.661914161 5.263699 5.43468 4.285996 8.331873 8.549366 7.988762 IFT74 0.848575892 0.044592081 0.018990813 8.658990602 3.839948 2.023048 2.165421 6.954147 6.205902 5.106393 SLC38A6 0.837970217 0.044745607 0.01960803 8.658990602 3.839948 2.809601 3.90836 6.954147 7.138979 5.900694 VCL 0.910069355 0.044159136 0.015899285 8.656953078 7.744853 7.899144 7.295639 10.409498 10.840623 11.508465 UCHL5 0.755981081 0.046488705 0.025146649 8.655547354 4.309025 2.023048 3.764125 7.42265 6.613395 5.426231 FBX032 0.690675452 0.048985317 0.030614495 8.654781361 6.099991 6.502398 4.449894 8.105092 9.615895 7.774634 LOC100499177 0.920983025 0.044110923 0.015288874 8.653934669 5.335413 6.049721 6.369239 9.094145 9.275744 9.163078 RCHY1 0.802212448 0.04534393 0.021880231 8.652637758 5.491121 4.80797 4.508334 8.604261 8.502167 6.942983 SLC22A18 0.820285527 0.045095391 0.020705002 8.651857506 3.819732 4.736586 2.995681 7.835902 5.857745 7.849596 ARRDC4 0.869845965 0.044335719 0.017881592 8.650177287 2.993831 3.360637 4.285996 7.144104 7.174648 6.106561 PTK2B 0.851872764 0.044480228 0.018760122 8.650177287 2.993831 3.360637 3.90836 7.477873 6.237456 6.106561 C6orf62 0.843535631 0.044654714 0.019228989 8.645917924 7.155835 5.362142 6.326717 9.102956 9.915181 9.438736 PPME1 0.86740201 0.044369384 0.018032664 8.634426507 5.056948 4.80797 4.449894 7.918071 7.25505 8.784285 LAP3 0.79142201 0.045499568 0.022588636 8.606724079 6.58615 6.638536 5.225216 8.566539 9.168974 9.744001 SCN11A 0.815387344 0.045173526 0.021025519 8.604122393 6.008206 4.736586 4.724406 7.394225 8.469821 9.113234 CLIP1 0.797114981 0.045366463 0.022171487 8.599916094 3.819732 4.911517 5.217616 8.993498 7.53715 6.924055 RNF144B 0.70437448 0.048408779 0.029387547 8.592589642 3.819732 2.406905 3.90836 7.70315 5.509998 5.580533 NCOA7 0.925703204 0.04407613 0.015101735 8.591368156 7.218633 6.983552 7.273415 10.617494 10.24167 10.086439 KHDRBS3 0.790694128 0.045520454 0.022620619 8.569370112 2.201691 4.911517 6.054038 8.014609 7.53715 8.010706 LRIG2 0.765385115 0.046178907 0.024440286 8.565823114 3.024504 2.023048 3.935222 5.252045 5.857745 7.033813 ATG14 0.889741842 0.044203301 0.017005784 8.564724264 5.700376 4.830496 5.723602 8.768324 8.220489 8.822008 MCTS1 0.900922875 0.044203301 0.016414427 8.562385284 6.792865 6.139057 6.175931 9.23707 9.492512 9.857343 PRRG4 0.899179892 0.044203301 0.016538959 8.549259441 5.491121 5.789702 5.609945 9.29204 8.36819 8.705744 RGPD3 0.79530244 0.04540117 0.02233821 8.54640041 4.263463 3.360637 4.724406 6.252746 7.819723 7.46072 SGCD 0.875124847 0.044285705 0.017668595 8.528383974 1.874444 4.413323 4.944468 6.954147 7.505595 7.825039 SPTBN1 0.813170398 0.045218796 0.021187479 8.523943798 7.893399 6.572071 7.132367 9.663593 10.589051 10.37995 C7orf59 0.882585744 0.044229452 0.017331745 8.517495099 6.008206 6.092406 6.012527 9.102956 9.228189 8.732403 FAM168B 0.85327035 0.044464174 0.018677101 8.516149859 5.753024 4.736586 4.724406 7.814607 8.2398 8.407967 DFFA 0.805456022 0.045318476 0.0216754 8.515900772 7.497182 7.458616 6.056062 9.146221 10.178018 11.489054 SPATS2L 0.936397596 0.043994974 0.014507656 8.500688673 6.099991 6.092406 6.355801 9.410337 9.44338 9.133378 NFYB 0.754270234 0.04655221 0.025328343 8.495161589 5.316227 4.830496 4.285996 6.651882 8.402869 8.074602 NKAPP1 0.940579679 0.043921714 0.014340252 8.495058686 2.201691 2.023048 2.165421 5.252045 5.509998 5.106393 SOX6 0.870878961 0.044325295 0.017838721 8.495058686 2.201691 3.32135 2.165421 5.252045 6.205902 5.900694 ARSE 0.858670798 0.044387761 0.018441647 8.495058686 1.874444 2.023048 2.165421 5.252045 5.165949 4.562324 QRICH1 0.805160045 0.045318476 0.02168901 8.495058686 2.201691 4.389936 2.165421 5.252045 6.861783 6.587378 ACYP1 0.791887166 0.045479433 0.022546444 8.495058686 3.839948 2.406905 2.165421 5.252045 6.205902 6.051818 URM1 0.686865305 0.049176261 0.030911875 8.495058686 4.815804 2.406905 2.165421 5.252045 6.237456 6.455366 PIGQ 0.674364361 0.049848381 0.032234774 8.495058686 4.209882 2.023048 2.165421 5.252045 5.165949 6.051818 CCDC30 0.606960698 0.055426536 0.041489622 8.495058686 1.874444 2.023048 2.165421 5.252045 5.165949 2.921909 CCDC15 0.606960698 0.055426536 0.041489622 8.495058686 1.874444 2.023048 2.165421 5.252045 5.165949 2.921909 ANO1 0.761899797 0.046345155 0.024739027 8.487023421 6.143785 7.08238 5.217616 9.229044 9.468155 8.519314 CTNNAL1 0.811742609 0.045218796 0.021262334 8.480248056 3.839948 5.789702 4.285996 8.447068 8.258856 6.924055 LOC100506421 0.924934963 0.04407613 0.01510854 8.475775753 1.874444 2.023048 2.165421 4.894482 5.920411 5.106393 LINC00052 0.924182515 0.044091888 0.015150732 8.475775753 1.874444 2.023048 2.165421 4.894482 5.857745 5.106393 ECHDC3 0.907319187 0.044173537 0.016029262 8.475775753 1.874444 2.023048 2.165421 4.718672 6.640994 5.106393 CEP41 0.885377915 0.044203301 0.01721674 8.475775753 1.874444 2.023048 2.165421 4.718672 5.353925 5.106393 AIF1 0.86999921 0.044335719 0.017874787 8.475775753 1.874444 2.023048 2.165421 5.448591 4.608763 5.106393 RBM12B 0.847625931 0.044619412 0.019044573 8.475775753 2.993831 2.023048 2.995681 6.498222 5.936219 5.106393 EHHADH 0.833549952 0.044797567 0.019802654 8.475775753 1.874444 2.023048 2.165421 7.074163 4.131418 5.106393 LCA5 0.820181613 0.045095391 0.020718612 8.475775753 1.874444 2.023048 2.165421 4.341916 5.317867 5.106393 SNX25 0.814986711 0.045198955 0.021088125 8.475775753 1.874444 2.023048 2.165421 6.183122 4.131418 5.106393 POC5 0.73885259 0.04712834 0.026477714 8.475775753 3.839948 2.023048 2.165421 6.283686 5.317867 5.106393 STAMBP 0.698314907 0.048774753 0.03002654 8.475775753 4.263463 2.023048 2.165421 5.448591 6.373501 5.106393 EPHA7 0.64932755 0.051527347 0.035147329 8.475775753 1.874444 2.023048 2.165421 5.579836 3.134528 5.106393 ZNHIT6 0.856650747 0.044407381 0.018525349 8.471647074 4.209882 3.872014 2.165421 6.339437 7.292524 6.69026 HMCN1 0.85270708 0.044464174 0.018717931 8.468658349 2.201691 3.872014 4.754917 6.954147 7.440337 6.69026 PCDHB11 0.800513531 0.045343936 0.021965975 8.468206122 3.024504 2.023048 2.165421 5.252045 4.797798 6.106561 TAS2R20 0.768022626 0.046157531 0.024266757 8.465714455 3.819732 2.809601 2.379345 5.891233 7.174648 5.091834 PRG4 0.579992784 0.058796241 0.046738346 8.465714455 1.874444 2.809601 2.165421 5.891233 5.306419 2.921909 ACTL6A 0.720605455 0.047703746 0.027862538 8.45712153 7.336579 2.406905 5.018694 7.835902 8.098861 8.974957 LOC400027 0.785532131 0.045624536 0.02293229 8.451652171 4.743564 2.023048 4.285996 7.36523 7.414086 6.106561 PICALM 0.861424022 0.044379352 0.018333447 8.432858648 6.949166 6.931478 5.974145 10.025188 9.59355 9.509806 HSP90AB1 0.815025156 0.045182971 0.021072474 8.425136669 10.259065 10.745814 10.670173 12.660133 13.744873 14.561793 NOTCH4 0.803454625 0.045338539 0.021821708 8.419102698 2.993831 2.023048 4.285996 6.067497 6.043524 6.618407 GPAA1 0.797839987 0.045355733 0.022123171 8.415447663 5.856559 4.351315 4.724406 7.177844 8.181074 8.929599 MITF 0.617721156 0.054216311 0.039811501 8.411751433 4.682076 3.360637 5.609945 5.252045 8.682351 7.988762 HSPH1 0.733633924 0.047307334 0.026815924 8.411542483 7.943836 9.255331 11.023067 11.732348 13.563241 12.327702 KRT8P41 0.916388001 0.044110923 0.015503232 8.411162839 2.201691 2.023048 2.165421 5.095353 5.306419 5.106393 PCDHB14 0.905670924 0.044173537 0.016131337 8.411162839 1.874444 2.023048 2.379345 5.095353 5.317867 5.091834 LOC344595 0.900761685 0.044203301 0.016421232 8.411162839 1.874444 2.023048 2.165421 5.095353 5.509998 4.790662 NANOG 0.899815359 0.044203301 0.016482477 8.411162839 1.874444 2.023048 2.165421 5.095353 4.797798 5.426231 CCDC18 0.894869372 0.044203301 0.016784621 8.411162839 1.874444 2.023048 2.165421 5.095353 5.306419 4.790662 CCDC121 0.894869372 0.044203301 0.016784621 8.411162839 1.874444 2.023048 2.165421 5.095353 5.306419 4.790662 AGBL2 0.879491627 0.044278935 0.017463083 8.411162839 1.874444 2.023048 2.165421 5.095353 4.608763 5.882028 KIAA1467 0.829259088 0.044930476 0.020181014 8.411162839 2.993831 2.023048 2.165421 5.095353 5.509998 5.426231 BET1 0.812567073 0.045218796 0.021214699 8.411162839 1.874444 2.023048 2.165421 5.095353 6.043524 4.146207 AGA 0.787156603 0.045564387 0.022802314 8.411162839 1.874444 2.023048 2.165421 5.095353 5.317867 4.146207 C3orf18 0.787049067 0.045564387 0.022809119 8.411162839 1.874444 2.023048 2.379345 5.095353 5.920411 4.146207 DNAJB14 0.78234296 0.045701235 0.023158898 8.411162839 1.874444 2.023048 2.995681 5.095353 6.237456 4.562324 EED 0.777273761 0.045858846 0.02351412 8.411162839 2.993831 2.023048 4.285996 5.095353 7.094585 6.73963 MBTPS2 0.771276234 0.046066162 0.024006805 8.411162839 1.874444 2.023048 2.995681 5.095353 6.237456 4.476242 KLHL3 0.765761688 0.046178907 0.024426676 8.411162839 3.350997 2.023048 3.90836 5.095353 7.414086 6.195186 RGR 0.740868363 0.047048421 0.026321198 8.411162839 1.874444 2.023048 2.379345 5.095353 6.774676 3.630092 HES5 0.727637047 0.047495226 0.027323579 8.411162839 1.874444 2.023048 2.379345 5.095353 3.571326 6.587378 NSUN7 0.708362428 0.048245878 0.028952705 8.411162839 1.874444 2.023048 2.165421 5.095353 5.353925 3.630092 C6orf168 0.705939209 0.048351237 0.029237836 8.411162839 1.874444 2.023048 2.165421 5.095353 5.306419 3.630092 TEX15 0.705939209 0.048351237 0.029237836 8.411162839 1.874444 2.023048 2.165421 5.095353 5.306419 3.630092 MYOZ3 0.62923349 0.053255542 0.038197346 8.411162839 1.874444 2.023048 2.379345 5.095353 6.189775 2.921909 RANBP6 0.605708464 0.0555885 0.041744811 8.411162839 1.874444 2.023048 2.165421 5.095353 5.306419 2.921909 SCRG1 0.671080899 0.05005437 0.032605648 8.408312292 1.874444 2.406905 2.995681 6.067497 3.571326 5.882028 TSIX 0.910581538 0.044159136 0.01587887 8.40768589 7.480194 7.800972 7.611303 10.475444 11.180031 10.683012 C3orf52 0.683984347 0.049369649 0.031292276 8.405506515 1.874444 4.351315 3.324375 7.42265 5.353925 5.426231 RNF170 0.915990274 0.044110923 0.015544063 8.404172917 3.819732 2.023048 3.324375 6.395481 6.861783 6.32627 COL14A1 0.814695923 0.045198955 0.02110854 8.401641006 5.856559 6.092406 6.326717 8.376156 9.516465 9.163078 KLF4 0.795919922 0.045374706 0.022261313 8.399742495 6.381847 6.931478 7.809663 10.001823 10.311787 9.620989 NET1 0.811044598 0.045237293 0.021315413 8.392620156 5.491121 3.360637 6.175931 9.245052 8.350533 7.640338 MFAP2 0.917027054 0.044110923 0.015462402 8.390670857 1.874444 2.023048 2.165421 4.739845 7.627877 5.091834 GIPC2 0.916772773 0.044110923 0.015489622 8.390670857 1.874444 2.023048 2.165421 6.664985 4.797798 5.091834 SNX12 0.898524281 0.044203301 0.016559374 8.390670857 1.874444 2.023048 2.165421 4.718672 6.043524 5.091834 ANO5 0.896255715 0.044203301 0.016685948 8.390670857 1.874444 2.023048 2.165421 5.320955 4.797798 5.091834 SH2D1A 0.891069296 0.044203301 0.016951344 8.390670857 1.874444 2.023048 2.165421 7.531061 4.539173 5.091834 PRORSD1P 0.889194701 0.044203301 0.017033004 8.390670857 1.874444 2.023048 2.379345 6.244586 4.797798 5.091834 SWI5 0.839169406 0.044732882 0.019561075 8.390670857 3.350997 2.023048 3.324375 7.33564 6.373501 5.091834 KANK4 0.805646801 0.045318476 0.021668595 8.390670857 1.874444 2.023048 2.165421 4.013424 6.549959 5.091834 PRADC1 0.804164743 0.045327183 0.021771351 8.390670857 3.350997 2.023048 2.165421 6.244586 5.317867 5.091834 GORAB 0.788810345 0.045550411 0.022715209 8.390670857 1.874444 2.023048 2.165421 4.013424 5.920411 5.091834 PRKACB 0.785292521 0.045643174 0.022962913 8.390670857 3.839948 2.023048 2.379345 5.320955 7.989035 5.091834 HILPDA 0.765708206 0.046178907 0.024433481 8.390670857 4.209882 2.023048 2.165421 5.705318 7.174648 5.091834 FCHSD2 0.755739016 0.046493188 0.025164342 8.390670857 3.350997 2.023048 2.165421 5.252045 5.509998 5.091834 FAM150B 0.745012666 0.04685274 0.026004083 8.390670857 1.874444 2.023048 2.165421 6.544171 3.571326 5.091834 ACP2 0.741932736 0.046959999 0.026211637 8.390670857 3.839948 2.023048 2.165421 6.396698 5.306419 5.091834 GSTA1 0.738730603 0.04712834 0.026506975 8.390670857 1.874444 2.023048 2.165421 6.339437 3.571326 5.091834 TXLNB 0.738730603 0.04712834 0.026506975 8.390670857 1.874444 2.023048 2.165421 6.339437 3.571326 5.091834 HOXA4 0.684163262 0.049360973 0.031262334 8.390670857 2.201691 2.023048 4.944468 7.144104 5.857745 5.091834 EMB 0.608999246 0.055156748 0.041141204 8.390670857 1.874444 2.023048 2.165421 7.243046 2.265287 5.091834 IL18RAP 0.601538747 0.056113873 0.042521266 8.390670857 1.874444 2.023048 2.165421 7.037879 2.265287 5.091834 NDST3 0.592106304 0.05714283 0.044185097 8.390670857 1.874444 2.023048 2.165421 2.820813 5.306419 5.091834 RHOB 0.831832053 0.044860922 0.019929228 8.386108414 9.099752 8.089403 8.050877 11.118879 11.527136 11.5836 PEAR1 0.859699373 0.044379352 0.018415107 8.38293672 5.335413 2.023048 5.723602 7.450526 8.402869 8.745549 GBF1 0.815087239 0.045182971 0.021052059 8.382380489 3.839948 2.406905 2.995681 6.063041 6.861783 5.580533 TMED10 0.66235715 0.050569223 0.033573324 8.381521898 4.815804 2.023048 2.379345 6.814118 5.353925 5.446557 CGGBP1 0.756540616 0.046450467 0.025090847 8.367552933 6.344798 4.911517 4.754917 8.915622 7.819723 7.988762 LOC100506686 0.809463467 0.045247607 0.021414086 8.366901741 4.209882 4.413323 5.544658 7.274575 7.819723 8.074602 OSTM1 0.719861441 0.047724223 0.027952365 8.363834676 5.897292 3.32135 3.324375 8.069577 7.191402 6.385515 TMEM33 0.836337932 0.044768725 0.0196754 8.352738314 6.186289 5.340619 3.764125 8.316805 8.402869 8.456743 TAP1 0.763300535 0.046274022 0.02463559 8.343133038 6.099991 4.389936 6.072169 7.450526 8.668166 9.922465 C8orf84 0.667962326 0.050279153 0.032963593 8.343133038 1.874444 4.389936 2.165421 7.450526 6.640994 3.630092 CXorf69 0.796652623 0.045374706 0.022213678 8.339795926 5.700376 4.413323 3.324375 7.897963 7.473335 7.46072 ZRANB2 0.786040139 0.045579058 0.022873767 8.329587462 5.491121 5.340619 5.592916 9.299725 8.549366 7.46072 STX17 0.829346688 0.044930476 0.020174209 8.323800179 5.779429 4.736586 2.165421 7.995811 7.793829 7.611911 ASCC3 0.830902165 0.044867325 0.019998639 8.317424162 2.993831 3.770995 2.995681 5.705318 7.767462 6.051818 PFKFB2 0.77657627 0.045873421 0.023601905 8.317424162 4.209882 2.023048 2.995681 5.448591 7.107836 6.051818 C14orf119 0.867040806 0.044369384 0.018046274 8.312325426 4.815804 4.351315 3.764125 7.477873 7.406567 7.255535 LOC285074 0.833969096 0.044797567 0.019761824 8.31066274 4.309025 4.911517 5.596986 8.604261 7.53715 7.96648 CYP20A1 0.788385705 0.045562713 0.02274379 8.297871814 7.931391 6.762934 6.919905 9.23707 10.543149 10.984132 C9orf40 0.90508547 0.044173537 0.016192583 8.284152046 2.201691 2.023048 2.379345 5.252045 5.353925 5.106393 KLHL9 0.698657454 0.048763723 0.029996597 8.282084617 3.819732 3.32135 3.764125 6.814118 7.138979 5.091834 FHL1 0.830267909 0.044867325 0.020080299 8.27999419 6.381847 3.360637 6.355801 9.431477 8.777924 8.519314 LINC00514 0.826187333 0.044936643 0.020338891 8.277855658 9.344671 9.026217 9.161448 11.570252 12.210705 12.438107 AIMP1 0.87587406 0.044285705 0.017641375 8.275906832 5.744513 5.297868 4.944468 8.346785 8.314558 8.424409 ZNF81 0.819113782 0.045111103 0.020791426 8.271467391 1.874444 2.809601 2.165421 5.728038 5.857745 4.476242 ELMOD3 0.801382326 0.045343936 0.021911535 8.269741685 2.993831 2.023048 2.995681 5.252045 6.043524 5.446557 IQCK 0.797621918 0.045355733 0.022143586 8.269741685 1.874444 2.023048 2.995681 4.739845 6.043524 5.091834 ANKRD10 0.848716249 0.044567264 0.018965635 8.258194188 6.58615 4.750708 6.012527 9.058353 8.777924 9.143346 LSM1 0.786471974 0.045579058 0.022846546 8.257971836 1.874444 3.872014 3.90836 6.954147 6.861783 5.426231 ACOT13 0.841084169 0.044701668 0.019412725 8.257476648 3.350997 3.872014 3.324375 6.396698 7.25505 6.051818 DIS3L 0.767968368 0.046157531 0.024273562 8.253886563 9.440001 9.542523 9.288789 11.362146 12.485075 12.978097 ZFR 0.704911433 0.048378239 0.029308608 8.250271702 6.143785 5.43468 5.702912 9.188227 8.817023 7.36177 PRKAA2 0.814068963 0.045212649 0.021158217 8.248873508 4.815804 4.351315 3.935222 8.361545 6.613395 7.395512 CRYM-AS1 0.743901277 0.046889341 0.026077577 8.242739537 4.209882 3.770995 5.702912 6.814118 8.098861 7.523109 ICA1L 0.753220592 0.04658639 0.02539231 8.23675328 7.497182 7.323707 7.557139 9.307369 10.539257 10.958955 DNTTIP2 0.81571606 0.045173526 0.021005104 8.216100517 6.949166 6.957749 6.326717 9.98762 8.963611 10.293075 NUP107 0.861700491 0.044379352 0.018313032 8.215451758 5.056948 5.487673 4.449894 7.937902 8.098861 8.095288 DENND4C 0.772015685 0.046057921 0.023930589 8.21022621 3.819732 6.044198 5.018694 6.857154 8.65384 8.986077 FAM115C 0.756569987 0.046450467 0.025084042 8.202927315 6.648293 6.391145 7.381261 8.864724 9.687973 10.4174 MAGI3 0.7599391 0.046382879 0.024854712 8.2024829 3.024504 3.360637 2.995681 6.396698 6.189775 5.106393 RBM48 0.832177105 0.044855041 0.019904729 8.195565886 3.024504 3.360637 2.165421 6.395481 5.920411 5.426231 TAGLN 0.747804758 0.046782073 0.025788363 8.186836992 8.8383 10.996101 9.542181 12.3874 11.871606 14.895969 CHML 0.737368706 0.047155325 0.026589316 8.186032839 4.209882 4.351315 5.702912 7.243046 7.819723 7.46072 ABLIM1 0.870126147 0.044335719 0.017861177 8.183836997 5.335413 6.03611 3.324375 8.122528 8.36819 8.822008 RYK 0.823278166 0.045019115 0.020528071 8.181309969 5.897292 4.911517 5.217616 8.433162 8.453372 7.943848 BIRC3 0.71487156 0.047877006 0.028318476 8.175526072 6.48761 6.670655 7.180931 10.698207 9.701967 8.374509 SEMA3G 0.776862426 0.045858868 0.023552229 8.169833097 2.201691 3.770995 3.764125 4.739845 6.794431 8.593895 C16orf88 0.748312739 0.046757859 0.025758421 8.158810472 4.263463 2.406905 2.995681 4.894482 6.774676 7.291822 ACTR10 0.723802268 0.047585406 0.027578088 8.158810472 4.263463 2.023048 2.995681 4.341916 7.187136 7.291822 CXCL12 0.702380903 0.048544976 0.029616196 8.141142202 7.497182 7.26179 9.310781 9.832037 12.336012 10.76277 CCDC66 0.730451266 0.047384624 0.027073835 8.139148993 4.815804 3.360637 2.379345 6.183122 6.640994 6.385515 MDC1 0.691360492 0.048955004 0.030572304 8.138890021 5.856559 3.32135 3.935222 6.960054 6.640994 8.010706 NMNAT2 0.707338859 0.048274546 0.029047976 8.135043224 1.874444 4.389936 3.324375 5.026959 7.414086 6.129407 IRS1 0.733165225 0.047307334 0.026877169 8.131021282 5.328526 3.770995 3.324375 8.628872 6.794431 6.195186 RBMY2FP 0.80341301 0.045338539 0.021828513 8.123966263 5.700376 4.351315 5.217616 7.582358 8.2398 8.340256 STAG2 0.640962114 0.052128403 0.036397414 8.122283953 3.819732 3.872014 5.544653 8.566539 8.160956 5.091834 LOC100505876 0.756782151 0.046448971 0.025066349 8.115403758 7.931391 7.581983 7.884888 9.727662 10.905551 11.101266 DPY19L4 0.730394791 0.047384624 0.02708064 8.115079366 3.350997 2.406905 3.764125 5.448591 6.78473 5.634184 BBX 0.885780763 0.044203301 0.017196325 8.114778375 6.48761 5.148082 6.175931 9.196483 9.401119 8.929599 XPNPEP1 0.761489127 0.046345155 0.024758081 8.112226742 4.815804 2.406905 2.165421 7.835902 7.406567 4.562324 CLYBL 0.841110018 0.044701668 0.01940592 8.111893222 1.874444 2.809601 2.379345 4.894482 5.353925 6.051818 LOC100129662 0.83150444 0.044867325 0.019971419 8.111893222 1.874444 2.023048 2.995681 4.894482 5.306419 5.874974 YIPF5 0.883354043 0.044229452 0.01731133 8.10960927 5.335413 4.750708 5.596986 8.616619 8.277663 8.11568 SPN 0.840004869 0.044722631 0.019493705 8.109557158 6.48761 6.670655 7.360327 9.23707 10.142544 10.37995 NIPA1 0.78539925 0.045643174 0.022956108 8.107885225 2.201691 2.406905 2.995681 7.109557 4.539173 5.426231 DUS4L 0.767707236 0.04616149 0.024298061 8.107885225 2.993831 2.406905 2.165421 6.396698 4.539173 5.426231 JAZF1 0.772657085 0.046036363 0.023876148 8.100927246 1.874444 3.32135 4.285996 6.339437 7.174648 5.446557 TM2D1 0.693421241 0.048932925 0.030380401 8.092755593 5.856559 4.389936 3.90836 7.109557 7.406567 7.611911 BCL2L2 0.716777767 0.047841399 0.028196666 8.087507289 5.056948 2.809601 3.90836 6.183122 7.138979 6.924055 MTMR12 0.86149738 0.044379352 0.018326642 8.084518213 4.682076 4.413323 3.90836 8.65307 6.794431 7.428484 C5orf43 0.705216871 0.048378239 0.029301803 8.061858448 4.263463 3.32135 2.995681 7.274575 6.608026 5.106393 SYNCRIP 0.841649364 0.044701668 0.01935148 8.056726703 6.186289 6.311907 6.83141 9.196483 9.418172 9.397686 C6orf108 0.797400571 0.045366463 0.022164682 8.051889558 4.815804 4.413323 3.324375 7.42265 7.440337 6.649696 SEMA5A 0.768706767 0.046113847 0.024177611 8.047138432 6.054828 4.830496 6.056062 7.976765 9.064538 8.534542 ZNF322 0.864149847 0.044377262 0.018151072 8.046882208 4.209882 3.360637 3.324375 6.954147 6.189775 7.218312 SLC39A8 0.886429459 0.044203301 0.017155495 8.038537485 5.263699 3.32135 4.724406 8.270632 7.598264 7.668215 COL1A2 0.768155168 0.046157531 0.024246342 8.036755239 8.646058 7.458616 8.80648 10.46523 13.508557 10.8042 PIGF 0.708034426 0.048268527 0.029014631 8.033820973 4.263463 2.406905 3.324375 7.243046 7.269549 4.562324 NFU1 0.782851117 0.045695042 0.023105138 8.03236783 4.963444 3.32135 4.285996 6.651882 7.473335 7.291822 PAQR5 0.793577729 0.04542938 0.022447091 8.022306766 5.316227 4.736586 3.90836 6.814118 7.740604 8.732403 LOC158696 0.903523105 0.044173537 0.016267438 8.021715481 1.874444 2.023048 2.165421 5.026959 6.205902 4.790662 SNORA72 0.895871497 0.044203301 0.016699558 8.021715481 1.874444 2.023048 2.165421 5.026959 4.797798 5.580533 ZNF354A 0.783865535 0.045695042 0.023043892 8.021715481 1.874444 2.023048 2.165421 5.026959 5.353925 4.146207 KATNAL1 0.771121005 0.04607418 0.024019735 8.021715481 4.309025 2.023048 2.379345 5.026959 6.608026 6.587378 C7orf61 0.728671444 0.047423411 0.027207894 8.021715481 1.874444 2.023048 2.379345 5.026959 6.551443 3.630092 FAM104B 0.708408573 0.04824159 0.028942497 8.021715481 1.874444 2.023048 2.165421 5.026959 5.306419 3.676349 ELP4 0.708408573 0.04824159 0.028942497 8.021715481 1.874444 2.023048 2.165421 5.026959 5.306419 3.676349 RPSA 0.697298053 0.04880813 0.030102076 8.021715481 1.874444 2.023048 2.379345 5.026959 3.571326 5.874974 TSR2 0.678608028 0.049556832 0.03177067 8.021715481 4.263463 2.023048 2.165421 5.026959 5.936219 5.634184 CRISPLD1 0.656360069 0.050987756 0.034207554 8.021715481 1.874444 2.023048 2.165421 5.026959 6.549959 2.921909 PTTG1 0.637509215 0.052501106 0.036991494 8.021715481 1.874444 2.023048 2.165421 5.026959 3.134528 5.446557 PTGES3 0.842914284 0.044657496 0.019253488 8.015380943 8.203921 7.756763 8.487278 11.094787 11.548591 10.759534 NOB1 0.702049597 0.048553714 0.029638653 8.01435311 4.963444 5.661685 3.90836 9.87896 7.96603 6.051818 CUTC 0.746733284 0.046800775 0.025865941 8.01051905 4.263463 2.023048 3.324375 5.252045 7.187136 6.32627 PCBD1 0.660483276 0.050683546 0.033752297 8.007619935 5.982974 5.789702 4.944468 10.048181 8.791075 6.45366 JAK2 0.851136583 0.044490827 0.018813882 8.002931958 1.874444 2.406905 2.165421 6.396698 5.165949 4.562324 LOC729513 0.821723408 0.045048325 0.020617897 8.002931958 3.350997 2.809601 2.165421 5.728038 5.165949 6.924055 RNF180 0.701707396 0.048571998 0.029678802 8.002931958 2.201691 2.023048 2.165421 5.705318 5.165949 3.630092 PCDHB3 0.701101694 0.048630415 0.029746172 8.002931958 1.874444 2.023048 2.165421 5.026959 5.165949 3.676349 ATP13A4 0.694116093 0.048919234 0.030347737 8.002931958 1.874444 2.023048 2.165421 5.026959 5.165949 3.630092 GBE1 0.678242629 0.049589172 0.031799251 8.002931958 4.309025 2.809601 2.165421 6.063041 5.165949 6.051818 ZAN 0.593619814 0.057018726 0.043874787 8.002931958 1.874444 2.023048 2.165421 5.026959 5.165949 2.921909 CGN 0.592891033 0.057080847 0.044019735 8.002931958 3.024504 2.023048 2.165421 7.074163 5.165949 2.921909 ADM 0.83990164 0.044722631 0.019507315 8.000088991 6.143785 5.148082 6.031658 8.331873 9.031674 9.103055 LIAS 0.782427778 0.045701235 0.023152093 7.991764305 5.491121 6.044198 6.769247 8.700282 9.042712 9.051056 NEMF 0.818859621 0.045111103 0.020805036 7.990913815 6.186289 5.297868 2.165421 8.628872 8.296229 7.722406 SLU7 0.921227883 0.044110923 0.015282069 7.989260489 5.982974 5.297868 6.031658 8.964784 8.904331 9.02972 ZNF250 0.818586679 0.045111103 0.020818646 7.987277482 7.595107 7.664061 7.250844 9.698891 10.592811 11.383675 DCAF8 0.869769911 0.044335719 0.017888397 7.984017169 5.304463 3.360637 6.072169 8.301578 8.71031 8.287303 LRP5 0.854560097 0.044464174 0.018622661 7.98032207 4.263463 4.830496 3.764125 7.25991 7.473335 7.28312 CDC37L1 0.759454112 0.046382879 0.024879211 7.98032207 4.263463 3.360637 3.324375 7.25991 7.138979 5.426231 VIM 0.646757146 0.051710823 0.035614835 7.973984909 11.358374 11.213413 12.538201 13.036939 14.425289 15.533502 RHOJ 0.574086263 0.059729834 0.048034025 7.973600661 5.658609 5.487673 4.449894 5.728038 8.65384 8.549611 COL5A2 0.727501921 0.047495226 0.027330384 7.972845827 6.306772 5.195784 7.422239 8.301578 10.417334 9.192178 MFSD1 0.840091587 0.044722631 0.019480095 7.969800186 5.263699 4.830496 5.544653 8.895478 8.033973 7.825039 HNRNPA2B1 0.718101819 0.047790154 0.028074175 7.95411622 8.493568 8.464054 9.054723 12.564496 11.48527 10.354432 MYO3B 0.71105044 0.048062795 0.028690711 7.949617131 7.841135 7.726519 8.011136 9.552198 11.002021 10.936201 PHF11 0.839534414 0.044722631 0.019534536 7.938317978 4.682076 4.413323 3.935222 7.556937 7.414086 6.924055 ETFA 0.886266549 0.044203301 0.017169105 7.925194216 4.743564 4.911517 2.165421 7.897963 7.713236 7.218312 BACE1 0.779368694 0.045829476 0.023349439 7.918023917 5.328526 3.872014 4.449894 6.857154 8.033973 7.582913 DENND5B 0.807007538 0.045297753 0.021572644 7.911318143 5.700376 2.809601 4.508334 7.33564 8.119857 7.492252 USP48 0.830738579 0.044867325 0.020005444 7.909022718 4.309025 3.770995 4.944468 7.210813 7.292524 7.428484 IRF2BP2 0.768794731 0.046108296 0.024157196 7.899537998 7.513971 7.197097 8.114773 11.235653 10.495739 9.724213 COMMD6 0.889647616 0.044203301 0.017012589 7.89545727 6.648293 8.278469 8.735088 11.259492 11.175024 11.56518 PAM 0.755462062 0.046505334 0.025196325 7.895091721 6.267718 4.830496 4.944468 7.42265 8.277663 9.248674 DUSP6 0.846693477 0.044634679 0.019101055 7.888082159 6.186289 6.092406 5.596986 8.41912 9.524361 9.072081 REV3L 0.708649131 0.04824159 0.02891868 7.883529254 4.743564 2.406905 4.944468 5.705318 7.793829 7.722406 RBBP7 0.762911834 0.046294386 0.02467574 7.873611376 5.056948 4.830496 5.571599 8.843852 8.033973 7.180104 WDR59 0.753027729 0.04658639 0.02540592 7.867493112 4.682076 4.351315 5.592916 7.748771 7.740604 7.327219 CHFR 0.779084376 0.045829476 0.023369854 7.864056854 3.350997 4.736586 2.379345 7.25991 6.205902 6.32627 CDC42EP3 0.716762042 0.047841399 0.028210276 7.861572572 4.682076 6.502398 5.217616 8.676869 7.656894 8.340256 STRBP 0.619899834 0.054008689 0.039490983 7.860276525 4.743564 4.389936 2.379345 8.222933 5.353925 6.051818 GAL3ST4 0.824814408 0.044949653 0.020423954 7.858042956 3.839948 4.413323 2.995681 6.814118 6.549959 6.931222 PSMD4 0.73408097 0.047307334 0.026781899 7.856783944 6.765086 5.340619 5.225216 9.067384 8.314558 8.287303 CAPZA1 0.777823648 0.045844227 0.023464444 7.852992711 6.678389 6.35207 5.389265 9.651632 8.751258 8.705744 FAM20B 0.823558103 0.045005314 0.020492004 7.83721444 5.263699 4.351315 5.018694 7.36523 7.989035 8.155622 RUFY3 0.83260516 0.04483949 0.019870024 7.835636934 4.743564 6.139057 5.609945 8.316805 8.579995 8.719135 MREG 0.769300725 0.046082352 0.024095951 7.830222225 3.819732 4.80797 4.285996 10.384422 7.25505 5.874974 ZNF292 0.813779885 0.045218796 0.021180674 7.827906858 4.815804 4.80797 5.723602 7.814607 7.767462 8.692228 DISC2 0.763795549 0.046221625 0.024578428 7.808259511 1.874444 2.406905 4.508334 4.718672 7.473335 6.618407 AKD1 0.859955472 0.044379352 0.018408302 7.804243338 2.201691 2.406905 2.165421 4.894482 5.165949 5.634184 TSC22D1 0.684803491 0.049319443 0.031183396 7.802114119 8.55164 8.359538 9.485302 12.449167 11.795338 10.284093 ZNF704 0.819630825 0.045111103 0.020764206 7.799917319 4.639409 2.809601 5.217616 7.36523 8.181074 7.03218 NR2F2 0.647631905 0.051640811 0.035444029 7.797351636 9.060289 4.830496 6.976024 9.552198 9.939008 10.039174 OGT 0.74781431 0.046782073 0.025781558 7.792875096 7.04469 7.664061 8.037751 11.024644 10.626217 9.532738 DGKB 0.74755534 0.046782073 0.025808778 7.777525921 1.874444 2.023048 3.324375 6.283686 4.608763 5.091834 CCDC91 0.708096674 0.048268527 0.028980606 7.77573104 6.099991 4.736586 3.764125 7.450526 7.767462 7.695565 ATAD2B 0.86912487 0.044335719 0.017922423 7.773866125 3.350997 3.360637 2.165421 6.183122 6.319269 5.882028 ETV6 0.760159006 0.046360115 0.024834978 7.767875877 4.815804 6.270596 5.389265 8.346785 8.469821 8.03232 MAP3K5 0.727223008 0.047508117 0.027352841 7.758931336 6.45321 4.413323 5.225216 8.801178 8.181074 7.640338 SMARCD1 0.802230384 0.04534393 0.021873426 7.740283892 3.024504 3.32135 4.508334 5.579836 7.440337 7.46072 CNIH 0.698760437 0.048763723 0.029989792 7.713311298 4.263463 2.023048 3.324375 7.210813 4.797798 6.385515 TANC1 0.883253265 0.044229452 0.017318135 7.713234896 4.639409 5.297868 5.018694 7.918071 7.96603 8.175185 CAB39 0.768183294 0.046157531 0.024239537 7.713234896 3.839948 5.661685 5.018694 8.566539 7.96603 7.03218 C7orf60 0.653334383 0.051215566 0.034617217 7.711545169 2.201691 2.406905 3.764125 7.177844 5.353925 4.146207 TRIM33 0.730215695 0.047384624 0.027101055 7.70881774 4.309025 5.340619 6.410545 9.196483 8.502167 7.255535 CCNYL1 0.899000976 0.044203301 0.016545764 7.695263555 5.328526 5.195784 5.225216 8.139755 8.160956 8.440667 NIT1 0.853213811 0.044464174 0.018683906 7.689967805 5.263699 5.340619 5.723602 8.206677 8.453372 8.340256 TRIM78P 0.835956809 0.044768725 0.01968901 7.682682037 1.874444 2.023048 2.379345 5.320955 4.608763 5.091834 LOC146336 0.842295274 0.044657496 0.019301123 7.679287153 1.874444 2.023048 2.165421 5.095353 4.539173 5.106393 UBXN2B 0.812253916 0.045218796 0.021228309 7.679287153 2.993831 2.406905 2.165421 6.244586 5.165949 5.106393 ATPAF1 0.778898268 0.045829476 0.023383464 7.679287153 1.874444 3.360637 2.165421 5.026959 6.189775 5.106393 BARD1 0.753106087 0.04658639 0.025399115 7.679287153 2.201691 2.023048 2.165421 5.252045 4.131418 5.106393 FAIM 0.7375199 0.047140798 0.026573665 7.679287153 3.819732 2.809601 2.165421 6.063041 6.043524 5.106393 WDR37 0.718924396 0.047781016 0.028047635 7.679287153 2.993831 3.360637 2.165421 6.396698 5.165949 5.106393 BCAR3 0.665266692 0.050389557 0.033253488 7.679287153 3.350997 4.750708 2.165421 7.210813 6.319269 5.106393 CAPN3 0.619152689 0.054069926 0.039584212 7.679287153 1.874444 2.023048 2.165421 5.026959 3.134528 5.106393 GLTPD1 0.606919951 0.055428454 0.04149983 7.679287153 4.743564 2.406905 2.165421 6.395481 5.353925 5.106393 ASNS 0.833047644 0.044797567 0.019836679 7.678295396 5.304463 4.80797 2.995681 8.122528 7.187136 7.748756 ORAI1 0.620212169 0.054006231 0.039448792 7.676976239 5.753024 2.406905 2.995681 7.504712 5.936219 5.882028 ELF1 0.872703848 0.044299467 0.017731201 7.676299171 5.856559 2.406905 6.410545 9.049264 8.579995 8.79697 UACA 0.712347221 0.047984994 0.02854032 7.671109411 6.924263 5.362142 7.422239 8.301578 9.974027 10.166824 TAF9B 0.793898412 0.04542938 0.022419871 7.666253266 3.024504 2.023048 2.379345 5.448591 5.317867 5.091834 ARHGEF38 0.688544636 0.049115877 0.030796189 7.666253266 3.024504 2.023048 2.379345 7.42265 5.317867 3.676349 KCNMA1 0.58747444 0.05763794 0.045051378 7.666253266 3.024504 5.661685 2.379345 7.274575 5.317867 6.195186 SYF2 0.8112663 0.045231055 0.021302484 7.664387248 7.278811 6.03611 6.410545 10.115039 9.348715 9.23941 ARID5B 0.740984576 0.047036111 0.026306227 7.658259979 7.497182 6.184248 8.525393 9.958788 10.434198 10.550703 NUP153 0.73876637 0.04712834 0.026489963 7.642632392 6.765086 7.0583 8.355951 9.99237 10.550902 9.956785 RARS 0.834614926 0.044793607 0.019735965 7.640945632 5.856559 5.809601 3.764125 8.79031 8.453372 8.074602 TMEM126B 0.715902201 0.047867182 0.028263355 7.640849969 4.639409 2.809601 2.165421 5.743334 7.138979 5.580533 CXCR3 0.680210983 0.049490097 0.031604627 7.640849969 3.024504 2.809601 4.724406 5.743334 6.613395 6.129407 FLJ42709 0.676861777 0.049712169 0.031992514 7.640849969 4.209882 2.809601 5.609945 5.743334 7.793829 7.800057 SLC25A36 0.81733983 0.045152347 0.020879891 7.632138706 5.056948 4.911517 5.609945 9.651632 7.989035 7.523109 SELK 0.72501424 0.047570884 0.027494386 7.627713864 7.854379 7.240547 7.381261 10.78563 10.417334 9.329475 CCDC149 0.800129287 0.045343942 0.022010888 7.620746067 2.993831 3.32135 2.165421 5.095353 5.857745 6.618407 LOC100129716 0.750525992 0.046662281 0.025574005 7.620746067 1.874444 3.32135 2.165421 5.095353 6.774676 4.562324 LINC00473 0.70292959 0.048515004 0.029560395 7.620746067 3.024504 2.023048 2.165421 5.095353 6.189775 4.146207 LOC387723 0.57943649 0.058820115 0.046834297 7.620746067 2.201691 2.023048 2.165421 5.095353 5.317867 2.921909 ZDHHC21 0.571781645 0.060073766 0.048504934 7.620746067 2.993831 2.023048 2.165421 5.095353 6.613395 2.921909 ERO1L 0.803940431 0.045338539 0.021801293 7.616336552 4.209882 4.389936 3.324375 7.70315 7.138979 6.195186 NTAN1 0.791974089 0.045479433 0.022539639 7.616336552 4.209882 2.023048 2.995681 5.728038 7.138979 5.874974 SNX13 0.820390988 0.045095391 0.020698197 7.613823578 4.639409 4.389936 2.379345 7.274575 7.56803 6.455366 ATPBD4 0.825347764 0.044949653 0.020403539 7.611452577 1.874444 2.809601 2.165421 4.802615 5.317867 5.634184 CEP78 0.811511838 0.045218796 0.021289554 7.611452577 1.874444 2.809601 2.165421 4.802615 5.165949 5.634184 FREM1 0.659892932 0.050684199 0.033776795 7.611452577 1.874444 4.750708 4.724406 4.802615 8.332658 7.428484 PRIM2 0.768273111 0.04614639 0.024223886 7.605665154 3.024504 3.32135 2.379345 6.550689 5.306419 5.426231 NCOA2 0.885945538 0.044203301 0.017182715 7.602179765 2.201691 2.023048 2.165421 6.396698 4.797798 5.091834 STX18 0.871168165 0.044325295 0.017825111 7.602179765 1.874444 2.406905 2.165421 4.718672 6.78473 5.091834 GRIN2A 0.80972385 0.045243682 0.021394352 7.602179765 1.874444 2.809601 2.165421 4.894482 5.509998 5.091834 WDR12 0.782840697 0.045695042 0.023111943 7.602179765 2.201691 3.360637 2.165421 6.067497 5.306419 5.091834 SYDE2 0.76873736 0.046108296 0.024167404 7.602179765 1.874444 2.023048 2.165421 5.026959 4.131418 5.091834 ARMC12 0.76873736 0.046108296 0.024167404 7.602179765 1.874444 2.023048 2.165421 5.026959 4.131418 5.091834 MCF2L-AS1 0.751697786 0.04661125 0.025507996 7.602179765 3.024504 3.770995 2.165421 5.891233 6.774676 5.091834 ALDH18A1 0.693956305 0.048930884 0.030362708 7.602179765 4.263463 3.872014 2.165421 7.274575 6.549959 5.091834 C8orf55 0.659410532 0.050730781 0.033858455 7.600716786 2.993831 6.072636 3.764125 8.033165 6.549959 6.69026 NDUFAF3 0.768462664 0.04614639 0.024210276 7.591502453 6.099991 4.911517 3.324375 7.835902 8.453372 7.46072 RAB9B 0.862924433 0.044377262 0.018259952 7.586081293 1.874444 2.023048 2.379345 5.252045 4.797798 5.106393 RPL7A 0.75235937 0.046595104 0.025454917 7.586081293 1.874444 2.023048 3.324375 5.252045 4.797798 5.634184 MRS2P2 0.724795006 0.047575442 0.027512079 7.586081293 1.874444 2.023048 3.324375 5.095353 4.797798 5.426231 C5orf64 0.709365174 0.04824159 0.028865601 7.586081293 1.874444 2.406905 3.90836 6.183122 4.797798 5.634184 CTLA4 0.60942205 0.055130486 0.04104117 7.586081293 1.874444 2.023048 4.285996 5.705318 4.797798 5.091834 PRTFDC1 0.839756876 0.044722631 0.01951412 7.585455348 3.839948 3.32135 3.764125 6.244586 7.187136 6.455366 CEPT1 0.776237403 0.045884853 0.023630487 7.580626984 4.263463 4.413323 2.165421 7.33564 7.107836 5.900694 GNB2L1 0.687492571 0.049147961 0.03086492 7.578134819 10.078965 9.9999 10.148051 13.069894 13.026151 11.713056 FYN 0.810814514 0.045237293 0.021329023 7.578131912 6.054828 4.80797 5.702912 8.935488 8.624754 7.988762 BYSL 0.755534842 0.046493188 0.025171147 7.56026288 2.993831 2.809601 3.90836 5.728038 5.936219 6.195186 CD8A 0.696922996 0.04882091 0.030140864 7.559202339 3.819732 4.351315 6.072169 9.417418 7.269549 6.587378 ANKRD1 0.863867337 0.044377262 0.018171487 7.548648983 1.874444 2.023048 2.165421 5.448591 4.797798 4.790662 LIPH 0.816140328 0.045165524 0.020958149 7.548648983 1.874444 2.809601 2.165421 7.394225 4.797798 4.790662 NDUFAF1 0.756518884 0.046450467 0.025097652 7.548648983 1.874444 3.32135 2.165421 4.894482 6.78473 4.790662 MARK1 0.716157814 0.04786157 0.028252467 7.548648983 1.874444 2.023048 3.764125 4.894482 6.861783 4.790662 PKP1 0.630558238 0.053156193 0.037991153 7.548648983 1.874444 4.750708 2.165421 6.063041 5.936219 4.790662 LOC100189589 0.801323981 0.045343936 0.021925145 7.548056537 2.993831 3.32135 3.935222 6.244586 6.237456 6.195186 ANKRD65 0.761061875 0.046345577 0.024792106 7.548056537 1.874444 3.32135 2.379345 4.341916 6.237456 6.051818 PIK3R4 0.739944303 0.047086482 0.026380401 7.548056537 3.350997 3.32135 2.995681 6.498222 6.237456 5.091834 RAD51B 0.728440372 0.047423411 0.027228309 7.548056537 2.201691 3.32135 4.449894 5.705318 6.237456 6.618407 PDS5A 0.775735294 0.045911642 0.023693773 7.547148664 5.753024 4.351315 4.724406 7.450526 8 469821 7.640338 CSMD2 0.707289022 0.048274546 0.029061586 7.537311106 3.024504 2.406905 2.165421 5.320955 6.551443 4.146207 LOC100507117 0.585867443 0.05791529 0.045433141 7.537311106 1.874444 2.406905 2.165421 5.320955 5.306419 2.921909 PYROXD1 0.851839574 0.044480228 0.018766928 7.523926732 5.263699 5.148082 2.379345 7.631894 7.68534 8.175185 LOC678655 0.810736494 0.045237293 0.021342634 7.522934812 6.267718 7.0089 5.974145 9.744652 9.179013 9.08248 MUT 0.636248922 0.052582167 0.037130316 7.494086699 5.897292 2.023048 4.508334 7.726141 7.414086 5.874974 TRIM56 0.848477092 0.044592081 0.018997618 7.483610316 4.209882 4.351315 4.944468 7.074163 7.25505 9.303041 TMEM60 0.693023078 0.048944238 0.030414427 7.479704487 1.874444 2.023048 3.90836 6.811341 6.613395 3.630092 ARSK 0.684785355 0.049319443 0.031190201 7.47331937 3.350997 2.023048 2.165421 6.252746 6.189775 3.676349 FANCI 0.846377795 0.044634679 0.019114665 7.468719401 3.839948 2.023048 3.764125 6.664985 6.043524 6.722123 GMEB1 0.739213087 0.04712834 0.026450493 7.467550723 7.067614 6.060401 6.031658 8.122528 9.968249 9.717557 SPRY1 0.804374029 0.045327183 0.021744131 7.466978217 6.227577 3.360637 6.031658 8.665019 9.128102 7.988762 HYMAI 0.623997089 0.053689061 0.038863559 7.461751528 1.874444 2.406905 4.285996 5.252045 5.306419 5.426231 ZZZ3 0.769935166 0.046076407 0.024064648 7.453686465 4.209882 4.389936 3.90836 8.051486 7.107836 6.129407 GPR65 0.666988573 0.050336605 0.033120789 7.450365372 4.815804 2.406905 5.225216 8.122528 6.551443 6.32627 C3orf23 0.82284677 0.045019115 0.020562096 7.449371236 6.143785 6.391145 6.369239 8.676869 9.266358 9.67008 RNF220 0.679568449 0.049531477 0.031666553 7.446224102 5.744513 3.770995 4.508334 8.641022 7.870158 6.051818 EARS2 0.727710084 0.047495226 0.027309969 7.441285383 4.263463 2.406905 2.995681 5.891233 6.613395 5.580533 GINS4 0.617267407 0.054254364 0.039901327 7.441285383 5.491121 3.360637 2.995681 5.891233 6.551443 6.931222 GPX8 0.702481029 0.048544976 0.029609391 7.433238314 5.304463 3.770995 3.324375 6.664985 7.656894 6.385515 SORT1 0.63711194 0.052546395 0.037071793 7.433238314 5.856559 3.770995 2.379345 6.664985 6.189775 7.36177 TMEM134 0.601738393 0.056105963 0.04248656 7.433238314 6.58615 3.770995 3.90836 6.664985 7.138979 8.11568 FBXO3 0.864091616 0.044377262 0.018157877 7.431545968 2.201691 2.023048 2.379345 5.095353 6.373501 4.790662 HMGB3 0.750700989 0.046662281 0.025560395 7.431545968 2.201691 2.406905 3.90836 5.095353 5.920411 6.195186 BTBD6 0.699409776 0.048734593 0.029919701 7.431545968 2.201691 4.389936 2.379345 5.095353 7.269549 5.426231 SERAC1 0.583069196 0.05825755 0.045978224 7.431545968 2.201691 2.809601 4.754917 5.095353 5.857745 5.882028 PSD4 0.861682759 0.044379352 0.018319837 7.42354801 3.350997 3.360637 2.165421 6.252746 5.920411 6.106561 C10orf81 0.587198117 0.057666624 0.045099013 7.421604432 3.819732 4.351315 2.165421 7.243046 5.353925 5.091834 RPL32 0.845319379 0.044645837 0.019177271 7.415445118 11.786594 12.076687 12.425557 14.96722 15.017334 14.963458 CDHR3 0.651010356 0.05143697 0.034962232 7.41344061 2.201691 2.406905 4.449894 5.579836 6.237456 5.091834 RCL1 0.697474483 0.04880813 0.030088465 7.40577698 2.201691 5.297868 4.285996 7.70315 7.174648 5.882028 C10orf28 0.643107866 0.05194815 0.036151072 7.40577698 3.839948 4.389936 4.285996 7.33564 7.174648 5.446557 THOC2 0.878200836 0.044280042 0.017528411 7.399896104 5.056948 3.360637 4.724406 7.856887 7.56803 7.611911 LAPTM4B 0.795775867 0.045395954 0.022300102 7.399751791 6.008206 4.413323 5.217616 8.105092 8.277663 8.074602 BCL6 0.809263681 0.045247607 0.021434502 7.396110562 7.530567 6.877454 8.175959 10.991813 10.417334 10.117111 CD99P1 0.810552597 0.045237293 0.021356244 7.393956156 2.201691 2.023048 2.995681 5.448591 4.797798 5.882028 HINT2 0.752423287 0.046595104 0.025448112 7.392546222 4.682076 3.770995 3.90836 6.811341 6.794431 6.69026 BZW2 0.726567383 0.047532676 0.027397074 7.392546222 3.839948 4.413323 3.90836 8.875048 6.794431 5.634184 FAM193A 0.891201709 0.044203301 0.016937734 7.390879324 4.309025 3.360637 4.449894 7.33564 7.191402 7.152205 FAM160A2 0.884733169 0.044203301 0.01723035 7.385538475 4.209882 4.413323 4.449894 7.274575 7.094585 8.232333 SCML1 0.764023022 0.046193441 0.02452739 7.384763095 2.201691 3.32135 2.165421 5.026959 6.205902 5.091834 C1orf109 0.746450881 0.046811314 0.025915618 7.375499797 4.263463 4.830496 4.285996 6.544171 7.713236 7.218312 ATF1 0.808372501 0.045247607 0.021482137 7.373642718 4.309025 3.360637 2.995681 5.743334 7.191402 7.020304 LRRC49 0.589553641 0.057478449 0.044708404 7.372606205 3.839948 2.809601 2.995681 4.013424 6.189775 6.722123 USP1 0.720403854 0.047703746 0.027896563 7.367333842 2.993831 4.351315 5.225216 7.726141 7.942653 5.874974 BEX4 0.717780734 0.047825499 0.028118408 7.364139895 5.491121 5.487673 5.018694 9.049264 8.36819 6.924055 SNX19 0.626957483 0.05346854 0.038500851 7.354877469 5.856559 3.770995 2.995681 6.550689 7.138979 6.649696 C3orf17 0.777095221 0.045858868 0.023538619 7.348094196 5.263699 4.80797 3.935222 8.79031 7.68534 6.722123 FLJ31813 0.712371829 0.047984994 0.028533515 7.346562137 5.491121 5.148082 6.891005 8.286188 8.36819 9.018932 ANKRD36B 0.806244406 0.045315307 0.021637292 7.343001821 2.993831 2.809601 3.90836 6.252746 6.78473 5.634184 CEP70 0.812900991 0.045218796 0.021207894 7.342086404 3.024504 2.023048 3.764125 6.183122 5.857745 5.900694 HABP4 0.832386787 0.04483949 0.019883634 7.341727244 3.839948 2.406905 3.935222 6.811341 6.640994 6.129407 SDC2 0.758994848 0.046382879 0.024913236 7.340912228 5.744513 6.060401 6.282905 9.07636 9.158864 8.074602 TRIL 0.793572061 0.04542938 0.022453896 7.330111849 1.874444 3.32135 4.508334 6.063041 7.107836 6.195186 CARS2 0.829727223 0.044930476 0.020146989 7.325663398 4.963444 2.809601 4.754917 6.960054 7.627877 7.800057 IFT88 0.857804811 0.044387761 0.018468867 7.317923755 1.874444 2.023048 2.165421 4.894482 6.319269 4.562324 PKIA 0.847326835 0.044634679 0.01906703 7.317923755 1.874444 2.023048 2.165421 4.894482 4.539173 5.874974 NOX4 0.842608936 0.044657496 0.019267098 7.317923755 1.874444 2.023048 2.165421 4.894482 4.539173 5.634184 SUGT1P3 0.836675021 0.044768725 0.01966179 7.317923755 1.874444 2.023048 2.379345 4.894482 5.165949 4.790662 VPRBP 0.794666744 0.04542938 0.022368152 7.317923755 2.993831 2.023048 2.379345 4.894482 5.165949 6.195186 HTR1D 0.760520712 0.046360115 0.024828173 7.317923755 1.874444 2.023048 2.165421 4.894482 4.131418 5.106393 ZNF187 0.717025436 0.047840971 0.028172167 7.317923755 1.874444 2.023048 2.165421 4.894482 5.920411 3.630092 SLC9A7P1 0.714817592 0.047877006 0.028332086 7.317923755 1.874444 2.023048 2.165421 4.894482 5.857745 3.630092 TBCE 0.685331006 0.049314432 0.031141204 7.317923755 1.874444 2.023048 3.935222 4.894482 6.613395 4.790662 ETV3L 0.672706232 0.049933984 0.032399456 7.317923755 1.874444 2.023048 2.165421 4.894482 3.571326 5.091834 BEND5 0.634875537 0.05273953 0.03735148 7.317923755 1.874444 2.023048 2.165421 4.894482 6.237456 2.921909 C5orf54 0.593422432 0.057025989 0.043914257 7.317923755 1.874444 2.023048 2.165421 4.894482 5.317867 2.921909 COL11A1 0.592821047 0.057082126 0.044038789 7.317923755 1.874444 2.023048 2.165421 4.894482 5.306419 2.921909 ZNF789 0.592821047 0.057082126 0.044038789 7.317923755 1.874444 2.023048 2.165421 4.894482 5.306419 2.921909 LOC100133612 0.5852326 0.057986105 0.045571283 7.317923755 1.874444 2.023048 2.165421 4.894482 5.165949 2.921909 PLSCR1 0.790667624 0.045520454 0.022627424 7.314510097 6.054828 4.736586 7.056312 8.925589 8.842512 9.380933 WNK3 0.768420939 0.04614639 0.024217081 7.302675283 2.993831 3.32135 3.935222 6.339437 6.189775 5.874974 ENDOD1 0.755497831 0.046505334 0.02518952 7.302281111 4.743564 5.661685 2.995681 7.897963 7.066159 7.611911 ZNF7 0.706304347 0.048309794 0.029174549 7.298583355 4.963444 3.872014 3.324375 6.244586 7.191402 6.73963 SYK 0.684507067 0.049344803 0.031236475 7.297372046 6.186289 5.297868 5.571599 7.243046 9.053666 8.636861 ZBTB48 0.785622555 0.045624536 0.022925485 7.295447971 4.815804 4.351315 3.935222 6.811341 7.414086 7.218312 ASUN 0.768667555 0.046141453 0.024199388 7.295447971 3.819732 4.351315 2.995681 5.728038 7.094585 7.218312 RPP30 0.776648409 0.045873421 0.0235951 7.291349816 4.639409 5.43468 3.935222 7.656039 7.505595 7.395512 PTPRZ1 0.816546844 0.045165524 0.020937734 7.287388383 1.874444 2.809601 2.165421 4.739845 5.317867 5.634184 CNTN3 0.756675501 0.046450467 0.025077237 7.287388383 1.874444 3.32135 2.995681 4.739845 6.861783 5.634184 IL21R 0.707062274 0.04829046 0.02909493 7.287382786 2.201691 2.023048 3.324375 4.013424 6.189775 5.874974 CLCC1 0.742946112 0.046915454 0.02613542 7.285708041 5.779429 4.830496 4.944468 7.918071 7.819723 7.695565 GCLC 0.692727978 0.048944238 0.030428037 7.281727472 4.209882 3.360637 5.544653 7.074163 7.414086 6.722123 CDCA7L 0.643124834 0.051942518 0.036129296 7.270543995 1.874444 4.413323 2.995681 4.802615 5.857745 6.587378 PI4K2B 0.588550452 0.057530341 0.044860837 7.270543995 1.874444 2.023048 2.995681 5.579836 5.857745 2.921909 PDSS1 0.672508695 0.049933984 0.032440286 7.267895994 2.201691 4.80797 2.165421 5.026959 6.043524 6.618407 GPR56 0.781467311 0.04575418 0.023221504 7.257814679 3.350997 4.911517 3.935222 7.771052 6.640994 6.722123 COPS4 0.809545727 0.045247607 0.021407281 7.252655774 5.897292 6.03611 5.217616 8.331873 8.502167 8.894619 RABGAP1L 0.815486188 0.045173526 0.021018714 7.252075299 4.309025 2.406905 4.754917 7.167419 7.292524 6.722123 PRKCI 0.812963765 0.045218796 0.021201089 7.248244414 5.335413 6.060401 5.592916 8.190235 8.486085 8.918033 FMR1 0.71355444 0.047910176 0.02840558 7.241451953 4.963444 3.360637 3.935222 7.037879 7.819723 5.882028 UBE3A 0.733196316 0.047307334 0.026870364 7.240391762 5.856559 6.03611 7.003286 8.833301 8.892178 9.072081 SLC31A1 0.730237723 0.047384624 0.02709425 7.23766564 6.58615 5.487673 6.282905 8.014609 9.138429 9.486503 ARFIP1 0.712872602 0.047938332 0.028472269 7.235404488 4.682076 4.389936 3.324375 7.25991 7.53715 5.900694 WWC3 0.844920873 0.044645837 0.019184076 7.234256233 5.316227 4.830496 3.764125 8.139755 7.68534 7.523109 APBB2 0.776122793 0.045884853 0.023650902 7.23081806 6.45321 6.092406 6.054038 9.307369 8.486085 8.952456 CIRH1A 0.706179329 0.048342199 0.029201769 7.224925441 4.309025 3.32135 4.285996 7.877571 7.138979 5.426231 KIAA0196 0.73762439 0.047140798 0.026566859 7.207546316 4.963444 3.360637 3.935222 7.037879 6.78473 6.649696 ANGPTL1 0.676907287 0.049712169 0.031978904 7.207546316 5.328526 2.023048 3.935222 7.726141 6.78473 5.634184 FAM73A 0.785494721 0.045624536 0.022939095 7.204929585 4.682076 4.911517 5.723602 7.531061 8.296229 8.010706 PUS1 0.56991987 0.06033194 0.048923443 7.186379148 1.874444 3.360637 2.165421 5.705318 6.205902 2.921909 BMP4 0.788940003 0.045529634 0.022696836 7.186319743 3.819732 3.872014 5.609945 6.664985 7.740604 8.357484 LITAF 0.709557734 0.048237753 0.028848588 7.18266255 7.09018 6.931478 6.976024 10.351527 8.724089 9.820543 HEATR5A 0.806635887 0.045297753 0.021606669 7.18193748 4.263463 2.023048 3.935222 6.396698 7.107836 6.32627 NHEG1 0.846553239 0.044634679 0.01910786 7.181219266 1.874444 2.023048 2.165421 4.718672 5.165949 4.790662 CEP85 0.701970133 0.048553714 0.029652263 7.181219266 1.874444 3.770995 2.165421 4.718672 5.165949 6.32627 MED12L 0.697188968 0.04881728 0.030129976 7.181219266 1.874444 2.023048 3.90836 4.718672 5.509998 5.874974 NPFF 0.681036284 0.04946136 0.031537258 7.181219266 1.874444 2.406905 3.935222 4.718672 6.205902 5.426231 TYW1B 0.645111299 0.051836922 0.035906771 7.181219266 1.874444 2.023048 3.764125 4.718672 5.306419 5.106393 ATP1B4 0.810298486 0.045237293 0.021369854 7.181020739 3.350997 2.406905 2.995681 5.728038 5.509998 6.195186 IGBP1 0.726040359 0.047543032 0.027426335 7.179138163 5.700376 6.03611 6.527811 9.466036 8.87992 8.010706 PGM2 0.671798735 0.050003999 0.032532154 7.172124828 4.963444 3.770995 2.165421 7.074163 6.613395 5.580533 PAPLN 0.685945955 0.049293152 0.031045934 7.171187046 2.201691 4.413323 5.225216 5.728038 7.740604 7.255535 MEF2C 0.733396664 0.047307334 0.026849949 7.165328586 4.682076 4.413323 3.935222 7.394225 6.237456 7.523109 RPL15 0.854358563 0.044464174 0.018643076 7.162720388 10.414694 10.079831 10.175278 13.255201 13.246238 12.862923 SPRED2 0.638236089 0.052467325 0.03687785 7.154217959 4.743564 4.750708 3.90836 7.582358 7.91889 5.580533 RNF113A 0.78477747 0.045655746 0.022992174 7.149201367 5.056948 5.297868 4.724406 7.25991 7.89473 8.391335 TRMT1L 0.713028886 0.047932772 0.028461381 7.145483504 2.201691 3.770995 3.324375 5.320955 6.608026 5.580533 PPP1R11 0.619635141 0.054008689 0.039508676 7.145483504 5.744513 3.770995 2.379345 6.954147 6.608026 6.195186 CTSO 0.753340003 0.04658639 0.025385505 7.14421314 5.328526 6.311907 5.018694 7.631894 9.148683 8.503924 CAMK2N1 0.830457955 0.044867325 0.020053079 7.13622682 5.263699 3.360637 5.571599 8.376156 8.098861 7.582913 COL15A1 0.701088052 0.048630415 0.029752977 7.136156204 6.381847 5.487673 4.449894 6.954147 10.058027 8.32282 PCDHB10 0.853942577 0.044464174 0.018656686 7.133196051 1.874444 3.360637 3.764125 6.183122 6.373501 6.195186 ATF2 0.810653571 0.045237293 0.021349439 7.130724499 5.982974 4.80797 6.450701 9.204692 8.817023 8.391335 CCDC132 0.763297192 0.046274022 0.024642395 7.126729785 3.024504 3.32135 2.165421 6.811341 5.857745 4.790662 IL18 0.605685685 0.0555885 0.041751616 7.126729785 3.024504 3.770995 5.571599 7.33564 5.857745 6.618407 DROSHA 0.73382511 0.047307334 0.026795509 7.117861104 5.328526 4.736586 2.165421 8.156778 7.56803 6.129407 TCEANC2 0.699705494 0.048733855 0.029902007 7.115538594 6.707871 6.702075 7.77844 8.864724 9.789758 10.609413 GGCX 0.755328602 0.046505334 0.025223545 7.111431336 6.227577 6.702075 6.83141 8.641022 9.532215 9.801784 CHD9 0.766457585 0.046178907 0.024381763 7.10477409 5.491121 4.351315 4.508334 7.33564 8.549366 7.180104 P2RX7 0.629798503 0.053216585 0.038108881 7.104488334 5.328526 5.487673 6.054038 6.664985 8.87992 8.882768 SECISBP2L 0.748557452 0.046757859 0.025744811 7.102738926 5.491121 4.389936 4.449894 7.36523 7.942653 7.218312 PPP3R1 0.854419221 0.044464174 0.018636271 7.100875566 4.209882 4.389936 3.935222 7.037879 8.332658 6.73963 SGMS1 0.760721059 0.046345577 0.024805716 7.098138576 4.743564 2.809601 4.754917 7.582358 7.414086 6.385515 ENPP6 0.690086034 0.048987301 0.030645798 7.09003385 5.856559 5.43468 4.724406 6.954147 8.682351 8.357484 DBF4 0.712101991 0.0479972 0.028576387 7.086321933 3.839948 4.830496 5.389265 6.664985 7.819723 7.722406 EXOSC10 0.871225053 0.044325295 0.017811501 7.077566226 3.839948 3.872014 3.764125 7.243046 6.640994 6.587378 MICB 0.710568707 0.048127555 0.028736985 7.077566226 5.328526 2.023048 3.764125 6.339437 7.174648 6.587378 DLG1 0.778406374 0.045844227 0.023437224 7.076290445 5.328526 4.389936 4.944468 7.918071 7.767462 7.291822 NIPAL1 0.825890386 0.044948812 0.020358625 7.075462227 4.743564 4.750708 5.974145 7.477873 8.63937 8.79697 RNF219 0.714820141 0.047877006 0.028325281 7.073799703 2.201691 3.360637 2.165421 6.183122 5.936219 4.146207 PPP1R12A 0.805071325 0.045318476 0.02170262 7.059099505 7.021395 6.42919 6.527811 9.410337 9.637899 9.248674 NOS1 0.581518722 0.058540518 0.046349779 7.053750931 6.417969 6.537655 6.737132 7.531061 9.555522 9.380933 CCRN4L 0.762988137 0.04628868 0.024664852 7.053044594 4.639409 3.872014 3.324375 8.190235 6.043524 6.69026 NBEA 0.681070433 0.04946136 0.031530453 7.053044594 5.982974 3.872014 3.935222 7.33564 7.96603 6.69026 ANK2 0.748735756 0.046735137 0.025723716 7.042577861 3.819732 4.351315 5.389265 7.167419 7.107836 7.640338 KDELC2 0.633497261 0.052935473 0.037605988 6.992847126 4.963444 3.872014 5.544653 5.728038 8.350533 8.340256 KANSL3 0.785913456 0.045579058 0.022887377 6.989656732 5.304463 4.413323 5.389265 7.504712 7.89473 8.194487 RCAN2 0.635995267 0.052606547 0.037158898 6.989057445 5.744513 2.406905 4.724406 6.183122 6.640994 8.549611 ANKIB1 0.704780862 0.048386088 0.02933719 6.988741637 5.491121 4.351315 3.324375 8.254907 7.473335 6.129407 IL19 0.700450997 0.048706455 0.02983804 6.988741637 1.874444 2.809601 3.324375 4.739845 5.165949 6.129407 ATG16L1 0.766117383 0.046178907 0.024399456 6.98853082 5.328526 4.413323 3.764125 7.074163 7.793829 7.218312 RSL24D1 0.743761236 0.046889341 0.026091187 6.978466666 6.973646 6.572071 5.571599 10.106301 9.294336 8.374509 JAK1 0.694554329 0.048864786 0.030306227 6.975193152 5.658609 4.750708 6.919905 8.460842 8.963611 8.053616 TPR 0.604944544 0.055644091 0.041846206 6.966972979 4.309025 6.03611 3.764125 7.109557 7.53715 6.649696 RPL13 0.834558464 0.044793607 0.01974277 6.9658023 12.312072 12.382127 12.452391 15.182416 14.855391 16.262357 USP42 0.703637877 0.048490179 0.029475332 6.961765959 5.316227 5.195784 6.489771 8.553743 8.077554 8.11568 TIGD1 0.769040285 0.046096091 0.024124532 6.960231769 6.381847 5.340619 6.012527 8.139755 9.508524 8.692228 COQ6 0.676023832 0.049752474 0.032071453 6.952301537 5.744513 4.413323 3.764125 7.210813 7.187136 7.255535 DNPEP 0.73273744 0.047310912 0.026909833 6.940206389 9.292103 9.410824 9.465832 11.385805 12.205803 12.340755 LOC100287846 0.793906389 0.04542938 0.022413066 6.937762426 5.700376 6.060401 5.723602 8.222933 8.518072 9.123341 SCAI 0.756851866 0.046433585 0.025050698 6.933495421 6.792865 6.228068 7.339085 9.02165 9.687973 9.939727 BZW1 0.856705442 0.044407381 0.018518544 6.932859883 7.355332 7.615377 7.360327 10.391631 10.408827 10.142182 FLJ31662 0.76712426 0.04617033 0.024360667 6.930558324 3.839948 3.872014 4.508334 6.664985 6.861783 6.649696 STUB1 0.80439964 0.045327183 0.021730521 6.910860268 5.316227 4.80797 5.018694 8.105092 7.53715 7.825039 ZNF394 0.734361412 0.047307334 0.026766247 6.907737242 5.056948 4.351315 4.724406 7.607339 7.845161 6.69026 PPAP2A 0.765241038 0.046178907 0.024453896 6.906274427 5.658609 4.389936 4.724406 7.177844 8.098861 8.010706 ZKSCAN1 0.772812667 0.046036363 0.023869343 6.902980997 6.186289 6.060401 5.544653 8.331873 9.218487 8.503924 DOCK11 0.690527769 0.048985317 0.0306213 6.901459957 2.201691 2.023048 3.935222 5.320955 4.608763 6.722123 CASP4 0.778736139 0.045829476 0.023390269 6.899848881 1.874444 2.023048 3.764125 6.550689 4.539173 6.129407 ZFAND6 0.682436794 0.04941326 0.031437224 6.899848881 2.993831 2.023048 3.764125 6.550689 5.165949 5.091834 LOC285972 0.708701085 0.04824159 0.028911875 6.893930944 4.963444 6.391145 5.974145 7.748771 8.314558 9.60665 SEC24B 0.707301819 0.048274546 0.029054781 6.890989591 4.263463 4.389936 4.508334 8.676869 7.174648 5.882028 SGK1 0.793395313 0.04542938 0.022467506 6.890539196 6.45321 6.537655 6.175931 10.771883 9.237827 8.472642 CROCCP3 0.739952749 0.047086482 0.026373596 6.888503936 4.209882 4.830496 4.508334 6.339437 7.292524 8.579284 GUK1 0.684513781 0.049344803 0.03122967 6.883850407 7.513971 7.631788 7.825025 10.608241 9.357582 10.469833 CCNG2 0.568127385 0.060662455 0.049383464 6.881073303 5.316227 4.389936 6.704285 9.687221 8.098861 6.195186 BAAT 0.72717691 0.047508117 0.027359646 6.87757626 2.993831 2.406905 3.90836 4.739845 6.608026 6.69026 NDUFS2 0.719490934 0.047752902 0.027991834 6.875265914 6.099991 4.830496 2.995681 8.122528 7.191402 7.611911 KCTD6 0.724043748 0.047585406 0.027544063 6.870657215 4.263463 3.770995 2.995681 7.074163 6.551443 5.634184 IPO7 0.648457328 0.051584246 0.03528411 6.870552983 5.700376 6.391145 5.609945 9.171571 8.609988 7.352555 SLC17A5 0.741043196 0.047036111 0.026292617 6.868746927 4.963444 4.351315 3.764125 6.544171 8.011679 6.942983 CYP3A4 0.709782224 0.04819475 0.028808438 6.867897172 5.335413 3.872014 5.225216 6.651882 8.200916 7.873743 NLRC3 0.790929545 0.045520454 0.022613814 6.866464843 2.201691 2.023048 3.90836 4.802615 6.551443 6.385515 PHYHIPL 0.753340396 0.04658639 0.0253787 6.866464843 1.874444 2.023048 2.995681 4.802615 4.608763 6.106561 TRPM1 0.713670454 0.047910176 0.028398775 6.866464843 1.874444 2.023048 2.165421 4.802615 5.857745 3.676349 C5orf63 0.672477559 0.049933984 0.032447091 6.866464843 4.263463 2.023048 2.165421 4.802615 6.205902 5.634184 CYS1 0.567105836 0.060808506 0.049521606 6.866464843 1.874444 2.023048 2.379345 4.802615 5.306419 2.921909 CROCC 0.67232718 0.049970781 0.032487921 6.866359717 4.743564 3.32135 4.508334 5.705318 7.31791 7.523109 CFLAR 0.81304772 0.045218796 0.021194284 6.849277396 10.610849 9.990385 10.399636 12.72221 13.98053 13.175588 C14orf109 0.828962535 0.044930476 0.020201429 6.84357683 1.874444 2.023048 2.379345 6.550689 4.797798 4.562324 GKAP1 0.821677832 0.045048325 0.020624702 6.84357683 1.874444 2.023048 2.165421 5.095353 4.797798 4.562324 MUC15 0.815112827 0.045182971 0.021045253 6.84357683 1.874444 2.023048 2.165421 5.320955 4.797798 4.476242 NME5 0.800585288 0.045343936 0.021952365 6.84357683 1.874444 2.023048 2.165421 6.811341 4.797798 4.146207 SWT1 0.794489417 0.04542938 0.022388568 6.84357683 1.874444 2.023048 2.165421 6.498222 4.797798 4.146207 SLC25A16 0.766653308 0.046178907 0.024374957 6.84357683 1.874444 2.023048 2.379345 6.183122 4.797798 4.146207 C3orf71 0.761848503 0.046345155 0.024751276 6.84357683 2.993831 2.023048 2.165421 5.026959 4.797798 5.634184 NAT1 0.732633772 0.047319258 0.026931609 6.84357683 1.874444 2.023048 2.165421 6.498222 4.797798 3.676349 NRG4 0.722097878 0.047646206 0.027733243 6.84357683 1.874444 2.023048 2.165421 6.339437 4.797798 3.630092 DHX57 0.720454539 0.047703746 0.027882953 6.84357683 3.839948 2.023048 2.165421 6.395481 4.797798 5.426231 RPP40 0.720093979 0.047711776 0.027922423 6.84357683 1.874444 2.023048 2.165421 6.067497 4.797798 3.676349 MIR567 0.698021359 0.04880344 0.03005376 6.84357683 1.874444 2.023048 2.165421 5.448591 4.797798 3.676349 C3orf43 0.682646231 0.049399307 0.031397074 6.84357683 1.874444 2.023048 2.165421 5.252045 4.797798 3.630092 RAB30 0.681954283 0.049428793 0.03148622 6.84357683 1.874444 2.023048 2.165421 5.095353 4.797798 3.676349 RTP4 0.672321344 0.049970781 0.032494726 6.84357683 1.874444 2.023048 2.165421 7.607339 4.797798 2.921909 CTAGE5 0.671451522 0.050012479 0.03255461 6.84357683 1.874444 2.023048 2.165421 5.026959 4.797798 3.630092 CIDEC 0.657691512 0.05087892 0.034083702 6.84357683 1.874444 2.023048 2.165421 7.109557 4.797798 2.921909 C4BPA 0.633586811 0.052918525 0.037585573 6.84357683 1.874444 2.023048 2.165421 6.395481 4.797798 2.921909 GPR18 0.633586811 0.052918525 0.037585573 6.84357683 1.874444 2.023048 2.165421 6.395481 4.797798 2.921909 ABCG5 0.629404622 0.053243865 0.038178972 6.84357683 1.874444 2.023048 2.165421 6.283686 4.797798 2.921909 TMEM125 0.621233243 0.053905072 0.039309969 6.84357683 1.874444 2.023048 2.379345 6.544171 4.797798 2.921909 MSH5 0.610755906 0.054914277 0.040784621 6.84357683 2.201691 2.023048 4.449894 5.891233 4.797798 5.446557 FAM83B 0.59343521 0.057025989 0.043907452 6.84357683 1.874444 2.023048 2.165421 5.448591 4.797798 2.921909 PCDH17 0.579470453 0.058820115 0.046827492 6.84357683 3.839948 2.023048 3.90836 5.026959 4.797798 7.327219 LOC100129858 0.574964563 0.059590623 0.047831916 6.84357683 1.874444 2.023048 2.165421 5.095353 4.797798 2.921909 GRHL2 0.574964563 0.059590623 0.047831916 6.84357683 1.874444 2.023048 2.165421 5.095353 4.797798 2.921909 RGS6 0.574301071 0.05968693 0.047956448 6.84357683 5.982974 2.023048 2.165421 6.811341 4.797798 6.618407 LOC145474 0.571102763 0.060240587 0.048706363 6.84357683 1.874444 2.023048 2.165421 5.026959 4.797798 2.921909 FAM90A1 0.571102763 0.060240587 0.048706363 6.84357683 1.874444 2.023048 2.165421 5.026959 4.797798 2.921909 FRMPD4 0.571102763 0.060240587 0.048706363 6.84357683 1.874444 2.023048 2.165421 5.026959 4.797798 2.921909 H2AFX 0.586387877 0.057789468 0.045252127 6.842157888 5.897292 5.789702 6.072169 6.954147 8.724089 8.84662 STK10 0.778693091 0.045838382 0.023402518 6.841989478 4.263463 4.80797 3.935222 7.037879 6.608026 8.095288 TMEM67 0.785938447 0.045579058 0.022880572 6.841856282 6.306772 4.80797 4.944468 7.582358 9.064538 8.549611 CHN2 0.759611025 0.046382879 0.024872406 6.836116085 1.874444 3.770995 2.165421 6.544171 4.608763 5.882028 ACSS3 0.584539044 0.058094288 0.045711466 6.83179936 5.700376 4.389936 5.018694 5.743334 8.220489 8.472642 C5orf22 0.674560796 0.04983446 0.032208915 6.825487821 4.263463 2.809601 3.764125 7.144104 5.936219 5.580533 ATP6V1H 0.605840477 0.055562083 0.041714188 6.824898254 6.648293 5.148082 3.764125 8.105092 7.91889 7.033813 DFFB 0.645325588 0.051831344 0.035840082 6.822187473 4.682076 2.809601 4.944468 5.579836 7.187136 7.722406 MPP7 0.733355119 0.047307334 0.026863559 6.82102268 4.263463 5.148082 2.379345 7.918071 6.319269 6.73963 GATAD1 0.80421962 0.045327183 0.021757741 6.811921071 6.707871 6.184248 6.670675 8.905585 9.708913 9.438736 F3 0.666917081 0.050336605 0.033134399 6.810534237 4.309025 4.830496 3.324375 6.244586 7.598264 6.32627 C6orf115 0.849969076 0.044510429 0.01889214 6.809808289 1.874444 2.023048 2.165421 6.183122 4.608763 4.790662 WDR78 0.838771668 0.044732882 0.019574685 6.809808289 1.874444 2.023048 2.165421 6.067497 4.539173 4.790662 BCMO1 0.831112204 0.044867325 0.019985029 6.809808289 1.874444 2.023048 2.165421 4.739845 4.797798 4.790662 ABCG2 0.827007715 0.044930476 0.020277645 6.809808289 1.874444 2.023048 2.165421 5.448591 4.539173 4.790662 SH2D3C 0.826899676 0.044930476 0.02028445 6.809808289 2.201691 2.023048 2.165421 5.095353 4.797798 4.790662 BBIP1 0.730748004 0.047384624 0.027060225 6.809808289 3.350997 2.023048 2.995681 5.320955 7.094585 4.790662 TMEM69 0.703897431 0.048451596 0.029436543 6.809808289 4.815804 2.023048 2.165421 7.109557 6.319269 4.790662 LOC731424 0.691837333 0.048955004 0.030524668 6.809808289 3.024504 2.023048 2.995681 6.550689 4.797798 4.790662 NCAM1 0.686022455 0.049293152 0.031035046 6.809808289 3.350997 2.023048 2.379345 5.320955 5.165949 4.790662 ILDR1 0.665776484 0.050365391 0.033197686 6.809808289 1.874444 2.023048 2.165421 5.095353 3.571326 4.790662 OXGR1 0.662186006 0.050577128 0.033595781 6.809808289 1.874444 2.023048 2.165421 5.026959 3.571326 4.790662 ODZ4 0.651954127 0.051325457 0.0348377 6.809808289 3.819732 2.023048 2.165421 5.579836 5.165949 4.790662 DNAJC14 0.644724495 0.051844669 0.035928547 6.809808289 3.839948 2.023048 2.995681 5.095353 6.794431 4.790662 TMEM223 0.608770855 0.055170585 0.041167064 6.809808289 4.639409 2.023048 2.165421 5.579836 6.043524 4.790662 ATP6V1E2 0.600504806 0.056318704 0.042763525 6.809808289 1.874444 2.023048 3.90836 4.739845 5.317867 4.790662 EXOSC1 0.815820419 0.045173526 0.020998299 6.805878528 4.743564 4.413323 3.764125 7.210813 7.138979 7.180104 AFF4 0.792169513 0.045455125 0.022515822 6.787369723 7.530567 7.152299 7.557139 10.395222 10.29342 9.776388 DAAM1 0.701480993 0.048577236 0.02968969 6.780186296 5.304463 4.413323 2.995681 8.033165 7.174648 6.129407 PWP1 0.606274027 0.055476612 0.041610071 6.779672353 3.819732 6.03611 4.508334 6.651882 7.269549 7.611911 TBL1XR1 0.685258175 0.049314432 0.03114801 6.776529125 6.143785 5.340619 6.369239 9.146221 8.904331 7.611911 CMPK1 0.742103002 0.046946487 0.026196666 6.772494116 7.641685 6.732825 5.609945 10.123723 9.492512 9.040427 FMNL2 0.76368763 0.046237294 0.024600885 6.772386219 5.328526 5.789702 5.544653 7.771052 8.549366 8.357484 C1orf55 0.756424277 0.046450467 0.025111262 6.76997093 4.963444 4.351315 5.217616 7.976765 7.440337 7.218312 UBE2L6 0.669230773 0.050138385 0.032794148 6.765711557 6.417969 4.351315 4.944468 7.109557 8.609988 7.988762 LOC100505854 0.772574981 0.046036363 0.023889758 6.758137251 3.819732 2.023048 3.90836 6.664985 6.205902 5.882028 C7orf30 0.806785494 0.045297753 0.021593059 6.738454453 5.304463 4.830496 2.995681 7.394225 7.68534 7.582913 FBXO21 0.690164554 0.048987301 0.030638993 6.735575466 5.856559 5.43468 4.754917 7.037879 8.277663 8.60836 ZAK 0.68577198 0.049293152 0.031086764 6.731244415 8.096549 7.197097 7.401896 9.284314 10.152769 11.136626 PLAGL1 0.604625764 0.055684088 0.041911535 6.716481984 3.819732 4.750708 6.601009 7.177844 9.348715 6.618407 TCF19 0.722740151 0.04762218 0.027674039 6.716237063 1.874444 2.023048 2.995681 5.743334 4.797798 4.476242 TRIM36 0.654977526 0.051064299 0.034393331 6.716237063 1.874444 2.023048 2.995681 5.743334 5.306419 3.630092 TPD52L1 0.752045018 0.0466011 0.025481456 6.711764035 5.700376 6.537655 3.935222 8.447068 8.564762 8.194487 GNRHR2 0.714752821 0.047877006 0.028345696 6.71044272 4.682076 4.351315 3.935222 6.244586 7.107836 7.428484 CYFIP1 0.758405425 0.046395081 0.024935012 6.709399216 5.856559 4.413323 4.285996 8.540832 7.845161 7.03218 CCDC152 0.708058857 0.048268527 0.028994216 6.702081699 6.267718 6.270596 7.913913 9.012327 10.463244 9.329475 GFRA1 0.700760693 0.048679397 0.029799251 6.694378691 6.344798 5.362142 7.003286 8.105092 8.892178 10.060372 CSAD 0.696788 0.048824537 0.030158557 6.690442644 5.263699 5.362142 6.175931 7.144104 8.842512 8.918033 HOPX 0.765004983 0.046181862 0.024478394 6.688537771 3.350997 3.32135 5.018694 6.063041 7.25505 7.395512 SYT11 0.664619722 0.050400851 0.033316774 6.686557525 6.143785 4.413323 5.225216 7.274575 8.098861 7.96648 UBR5 0.753972134 0.046571395 0.025346717 6.686317861 5.491121 4.750708 6.012527 7.771052 8.518072 8.232333 TRIM14 0.769526997 0.046076407 0.024071453 6.676269236 6.792865 7.174872 7.401896 10.140938 9.991223 9.372483 RHOBTB1 0.762006604 0.046345155 0.024732222 6.674531336 3.819732 3.872014 3.324375 6.063041 6.78473 6.195186 MTX1 0.719108997 0.047781016 0.028034025 6.66652432 6.736762 5.340619 6.054038 9.252991 8.077554 8.918033 TMF1 0.703583454 0.048494719 0.029497788 6.663963635 6.554045 6.702075 5.018694 9.438455 8.963611 8.095288 EYA3 0.746296781 0.046811314 0.025936033 6.663656769 2.993831 3.872014 4.724406 6.550689 6.205902 7.46072 NEBL 0.570113424 0.06033194 0.048894862 6.662263214 3.350997 3.872014 5.217616 7.976765 6.608026 5.091834 C14orf142 0.807154464 0.045278798 0.02155427 6.654452133 1.874444 2.406905 2.165421 5.095353 4.608763 5.106393 PTPN7 0.773130477 0.046036363 0.023848928 6.654452133 1.874444 2.023048 3.90836 6.395481 4.608763 6.32627 PUS3 0.692493612 0.048955004 0.030463423 6.654452133 1.874444 3.770995 2.165421 5.705318 4.608763 5.634184 PBOV1 0.611091007 0.054867364 0.040706363 6.654452133 1.874444 2.023048 3.764125 5.026959 4.608763 5.091834 ADRB2 0.589571262 0.057478449 0.044701599 6.654452133 1.874444 4.750708 2.165421 5.579836 4.608763 6.106561 RSRC2 0.783008898 0.045695042 0.023098333 6.654315806 7.259029 7.174872 7.056312 10.686531 9.909162 9.380933 OBFC1 0.746450009 0.046811314 0.025922423 6.653425707 4.682076 4.80797 3.764125 6.498222 7.269549 7.873743 TADA1 0.671507456 0.050012479 0.032547805 6.653425707 3.350997 2.023048 3.764125 6.498222 6.189775 4.562324 SYNM 0.839253106 0.044732882 0.01955427 6.648832442 4.209882 4.351315 2.995681 7.074163 6.774676 6.942983 TPMT 0.803600089 0.045338539 0.021814903 6.64540175 3.350997 2.406905 2.995681 5.728038 5.857745 5.634184 FYCO1 0.806175784 0.045315307 0.021644097 6.642426559 3.819732 3.872014 3.324375 7.748771 6.551443 5.900694 ERGIC1 0.678168983 0.049604445 0.031818986 6.640369465 6.143785 4.389936 3.90836 8.875048 8.220489 6.106561 LRRN4CL 0.698804692 0.048763723 0.029982987 6.63895878 3.819732 4.413323 6.054038 6.550689 8.737737 7.695565 HOXC10 0.599161745 0.056396398 0.042994216 6.63895878 3.819732 2.809601 3.90836 6.550689 6.774676 4.476242 RPL35 0.801358162 0.045343936 0.02191834 6.638338764 10.960825 11.292965 10.774746 13.509545 13.505568 15.114718 CCNJL 0.796271953 0.045374706 0.022227288 6.636707286 3.819732 3.32135 3.935222 6.960054 6.549959 6.051818 EFHA2 0.608478707 0.055189127 0.041198367 6.636707286 5.897292 3.32135 3.324375 6.811341 7.269549 6.051818 WWP1 0.796244121 0.045374706 0.022234093 6.634429739 5.744513 5.148082 4.285996 8.474485 7.793829 7.774634 KLRG1 0.775319686 0.045964297 0.02374277 6.630241233 2.993831 2.406905 2.165421 4.894482 5.306419 5.634184 TTLL7 0.742195156 0.046946487 0.026183055 6.630241233 1.874444 2.023048 2.165421 4.894482 4.131418 4.790662 MIPOL1 0.730948555 0.047384624 0.027046614 6.630241233 3.024504 3.32135 2.165421 4.894482 5.857745 5.882028 C1orf180 0.671071474 0.05005437 0.032612453 6.630241233 1.874444 2.023048 2.165421 4.894482 4.797798 3.676349 CDYL2 0.654781832 0.051064299 0.034413746 6.630241233 1.874444 2.023048 2.165421 4.894482 3.571326 4.790662 MAGEA10 0.64791903 0.051631895 0.03539163 6.630241233 1.874444 2.406905 2.165421 4.894482 5.165949 3.630092 MESP1 0.624040881 0.053689061 0.038856754 6.630241233 2.993831 2.023048 2.165421 4.894482 6.205902 3.630092 DVL1 0.612310586 0.054772558 0.040558013 6.630241233 4.263463 4.413323 2.165421 4.894482 6.043524 7.943848 TFDP1 0.614187236 0.054577731 0.040301463 6.628593599 5.304463 2.406905 4.508334 8.033165 6.794431 5.446557 HDAC8 0.79229189 0.045455125 0.022509017 6.620996414 1.874444 2.809601 2.379345 4.894482 5.509998 5.106393 TLR4 0.64058893 0.052201656 0.036498129 6.61461189 3.024504 4.413323 5.723602 7.144104 7.138979 6.618407 MTUS1 0.65319224 0.051218943 0.034651922 6.598724016 5.856559 6.638536 7.180931 7.897963 9.903118 9.649245 LOC100506994 0.744997695 0.04685274 0.026010888 6.586995484 5.304463 4.389936 2.165421 7.109557 6.78473 7.291822 S100A10 0.659217236 0.050733231 0.033882953 6.585482971 7.786906 9.622716 8.114773 10.834062 10.785834 11.496849 EML1 0.804996697 0.045318476 0.021709425 6.58484187 3.024504 2.023048 3.324375 5.743334 6.043524 5.426231 RNF34 0.656276465 0.050987756 0.034221164 6.58484187 3.350997 2.809601 3.324375 6.395481 6.043524 4.562324 FAM95B1 0.602013037 0.056043118 0.042421232 6.581504775 1.874444 4.389936 4.754917 6.339437 7.473335 5.091834 SHMT2 0.616307176 0.054355679 0.040042872 6.579143031 6.008206 4.389936 3.764125 7.33564 7.107836 6.942983 FAM133B 0.833702616 0.044797567 0.019775434 6.574119148 1.874444 2.023048 2.165421 4.739845 5.936219 4.562324 OR9Q1 0.833432603 0.044797567 0.019809459 6.574119148 1.874444 2.023048 2.165421 4.739845 5.920411 4.562324 UPRT 0.825766128 0.044949653 0.020376318 6.574119148 1.874444 2.023048 2.165421 4.739845 5.509998 4.562324 FABP2 0.820609147 0.045095391 0.020684587 6.574119148 2.201691 2.023048 2.165421 4.739845 5.165949 4.790662 RS1 0.81231687 0.045218796 0.021221504 6.574119148 1.874444 2.023048 2.165421 4.739845 4.539173 5.106393 PTH2R 0.811855987 0.045218796 0.021248724 6.574119148 1.874444 2.023048 2.165421 4.739845 4.539173 5.091834 C1orf49 0.80845907 0.045247607 0.021475332 6.574119148 1.874444 2.023048 2.165421 4.739845 5.306419 4.476242 FASTKD1 0.772305866 0.046057921 0.023916979 6.574119148 3.024504 2.023048 2.379345 4.739845 5.509998 5.580533 KAL1 0.72974547 0.047394039 0.027136441 6.574119148 1.874444 2.023048 3.324375 4.739845 7.269549 4.476242 SPEF2 0.719176809 0.047780505 0.028023137 6.574119148 1.874444 2.023048 2.165421 4.739845 6.205902 3.676349 HEATR3 0.662680439 0.050529771 0.033537938 6.574119148 1.874444 2.023048 2.165421 4.739845 3.571326 5.106393 FAM176A 0.621384502 0.053905072 0.039296359 6.574119148 1.874444 2.023048 2.165421 4.739845 6.189775 2.921909 PTGR2 0.607910815 0.055264045 0.041317455 6.574119148 1.874444 2.023048 2.165421 4.739845 5.857745 2.921909 CADM2 0.582837549 0.058309181 0.046037428 6.574119148 1.874444 2.023048 2.165421 4.739845 5.317867 2.921909 PKD1L3 0.574911917 0.059591591 0.047842123 6.574119148 1.874444 2.023048 2.165421 4.739845 5.165949 2.921909 SMC2 0.699747928 0.048730157 0.029891119 6.57276684 3.350997 2.809601 2.165421 6.067497 4.608763 5.580533 IPCEF1 0.791576015 0.045499568 0.022581831 6.570522938 1.874444 2.023048 2.379345 5.095353 4.797798 4.562324 SNRNP200 0.772533931 0.046036363 0.023896563 6.565925363 7.259029 7.0089 6.175931 9.388882 9.974027 9.438736 ADPRHL2 0.679921625 0.049515112 0.031642055 6.554515277 3.350997 4.351315 2.379345 6.339437 6.794431 5.091834 FLJ23867 0.650574964 0.05147219 0.035014631 6.554515277 3.839948 4.80797 2.379345 7.274575 6.861783 5.091834 PCID2 0.761260126 0.046345577 0.024785301 6.549997035 3.839948 2.809601 3.90836 7.531061 6.551443 5.446557 HDAC9 0.816007434 0.045165524 0.020978564 6.549964635 2.993831 3.32135 3.324375 5.705318 5.920411 6.722123 ZNF326 0.647828733 0.051631895 0.035398435 6.543117209 6.267718 5.340619 4.508334 8.156778 8.181074 7.218312 RBM24 0.659841458 0.050686676 0.033787683 6.501719706 3.350997 3.32135 2.165421 4.894482 5.306419 6.051818 ANKRD50 0.682945167 0.049399307 0.031376659 6.500068692 3.024504 2.023048 5.217616 7.918071 7.414086 4.476242 PREB 0.592609126 0.057088939 0.044053079 6.499806249 4.743564 2.809601 2.165421 5.448591 5.509998 5.900694 LGALS12 0.74150387 0.046993264 0.026246342 6.495714591 1.874444 2.406905 2.995681 4.802615 5.353925 5.106393 COL12A1 0.717458629 0.047840971 0.028151752 6.48336025 5.316227 4.80797 6.704285 7.504712 9.053666 8.822008 FXN 0.739926373 0.047086482 0.026387207 6.481368213 5.316227 4.351315 5.723602 7.30543 8.4199 7.988762 VPS45 0.838165312 0.044732882 0.019588295 6.478341568 1.874444 2.023048 2.165421 4.718672 6.373501 4.562324 C6orf170 0.829862001 0.044925422 0.02013474 6.478341568 1.874444 2.023048 2.165421 4.718672 6.549959 4.476242 NUDT6 0.8214516 0.045095391 0.020657366 6.478341568 1.874444 2.023048 2.165421 4.718672 6.043524 4.476242 LOC286002 0.818579599 0.045111103 0.020825451 6.478341568 1.874444 2.023048 2.165421 4.718672 4.539173 5.446557 IL18BP 0.763993352 0.046193441 0.024541 6.478341568 1.874444 2.023048 2.165421 4.718672 4.131418 5.634184 LRP1B 0.7459248 0.046831501 0.025976863 6.478341568 1.874444 2.023048 2.165421 4.718672 4.131418 5.091834 GMCL1 0.7459248 0.046831501 0.025976863 6.478341568 1.874444 2.023048 2.165421 4.718672 4.131418 5.091834 UTP14C 0.706412629 0.048309794 0.029154134 6.478341568 1.874444 2.023048 2.165421 4.718672 5.857745 3.676349 BCS1L 0.687965602 0.049127354 0.03081116 6.478341568 4.309025 2.023048 2.379345 4.718672 6.613395 5.900694 ZNF185 0.687390901 0.049147961 0.03087853 6.478341568 1.874444 2.023048 2.165421 4.718672 5.509998 3.630092 LRRTM2 0.679494508 0.049531477 0.031686968 6.478341568 1.874444 2.023048 2.165421 4.718672 5.165949 3.676349 MFSD8 0.646729425 0.051721663 0.035630487 6.478341568 3.839948 2.023048 2.379345 4.718672 6.613395 4.790662 GZMK 0.573453137 0.059795609 0.04817625 6.478341568 1.874444 2.023048 2.165421 4.718672 5.165949 2.921909 POLD3 0.653196282 0.051218943 0.034645117 6.465632376 2.201691 2.023048 2.379345 4.894482 5.509998 3.630092 ZFPL1 0.662817535 0.050504642 0.033505274 6.464835878 6.054828 4.830496 3.764125 7.144104 7.767462 7.523109 AKIP1 0.721877647 0.047650501 0.027745492 6.464446376 3.350997 3.770995 3.324375 5.448591 6.043524 6.931222 FAM175A 0.658468956 0.050764584 0.033942838 6.464446376 3.350997 2.023048 3.764125 4.718672 6.043524 6.129407 RDH10 0.609457543 0.055130486 0.04102756 6.464446376 3.350997 2.023048 5.723602 7.167419 6.043524 5.900694 NUPL1 0.692517596 0.048944238 0.030448452 6.461629205 5.753024 4.736586 3.935222 7.177844 7.656894 7.428484 FAM49B 0.735325858 0.047271239 0.026707043 6.460579268 4.815804 5.195784 6.031658 8.723321 7.845161 7.668215 TRAP1 0.708952753 0.04824159 0.028884655 6.460440824 6.58615 6.35207 5.609945 8.301578 8.63937 9.414247 SERF2 0.73235543 0.047319258 0.026952024 6.458501571 7.595107 6.957749 7.401896 10.093095 10.558612 9.303041 LOC553103 0.652495679 0.051266842 0.034739027 6.458419077 2.201691 3.360637 4.724406 5.705318 6.319269 6.051818 TRAM1 0.6179319 0.05418054 0.039750936 6.454930432 8.502009 7.033812 6.326717 9.33006 10.041614 9.724213 EPHX2 0.69784744 0.04880344 0.030060565 6.451704131 1.874444 3.770995 4.724406 5.448591 7.414086 6.385515 TIGD6 0.688904041 0.049056873 0.030728139 6.451476692 5.328526 4.750708 3.764125 6.498222 7.440337 7.825039 CTDSPL 0.801857075 0.04534393 0.021893841 6.448250934 4.815804 4.736586 3.935222 7.504712 7.31791 7.152205 ZBTB2 0.640824842 0.052144602 0.036426676 6.445484384 4.815804 4.750708 5.389265 7.897963 8.077554 6.32627 LINC00467 0.831652972 0.044860922 0.019949643 6.443660661 1.874444 2.023048 2.165421 6.811341 4.608763 4.562324 PLG 0.825333299 0.044949653 0.020410344 6.443660661 1.874444 2.023048 2.165421 6.395481 4.608763 4.562324 C11orf82 0.824438303 0.044949653 0.020437564 6.443660661 1.874444 2.023048 2.165421 6.339437 4.608763 4.562324 SULT1C2 0.800502124 0.045343936 0.02197278 6.443660661 1.874444 2.023048 2.165421 4.718672 4.797798 4.562324 SLC16A9 0.793300266 0.04542938 0.022474311 6.443660661 1.874444 2.023048 2.165421 4.894482 4.608763 4.562324 PACRGL 0.770609706 0.046076407 0.024051038 6.443660661 1.874444 2.023048 2.379345 5.095353 4.608763 4.562324 AMPH 0.767546252 0.046164489 0.024322559 6.443660661 1.874444 2.023048 2.995681 5.448591 5.353925 4.562324 C2orf47 0.753529883 0.046580354 0.025365771 6.443660661 1.874444 2.809601 2.165421 6.664985 4.608763 4.562324 KIAA1586 0.750529313 0.046662281 0.0255672 6.443660661 1.874444 2.023048 2.995681 5.095353 5.509998 4.562324 PMP2 0.732387434 0.047319258 0.026945219 6.443660661 1.874444 2.023048 2.995681 5.026959 5.306419 4.562324 RGPD2 0.703458338 0.048494719 0.029518203 6.443660661 1.874444 2.406905 3.324375 6.811341 4.797798 4.562324 TAF5 0.697840522 0.04880344 0.03006737 6.443660661 1.874444 2.406905 2.995681 5.095353 5.165949 4.562324 LOC440300 0.697478812 0.04880813 0.03008166 6.443660661 1.874444 2.023048 3.324375 5.026959 5.509998 4.562324 TMEM154 0.674484583 0.049848381 0.032227969 6.443660661 1.874444 3.32135 2.165421 6.063041 4.608763 4.562324 LOC283070 0.59965454 0.056361464 0.042903028 6.443660661 1.874444 3.360637 2.995681 6.067497 4.608763 4.562324 SVIL 0.779152955 0.045829476 0.023363049 6.429842921 3.350997 5.789702 6.326717 8.474485 8.998044 7.825039 CXorf36 0.696448727 0.048851278 0.030190541 6.423717227 4.963444 4.351315 4.944468 6.183122 7.627877 8.870819 ALAD 0.749700277 0.046689047 0.025631848 6.418166844 5.304463 2.809601 4.724406 6.814118 7.406567 7.668215 PFDN2 0.811878551 0.045218796 0.021241919 6.41010187 3.839948 5.43468 5.217616 7.897963 7.740604 7.943848 CPEB2 0.715200732 0.047877006 0.028291256 6.407196 4.682076 4.80797 6.636262 8.700282 8.63937 7.36177 LOC150622 0.717627912 0.047839239 0.028140864 6.405749748 6.099991 6.03611 5.225216 8.779359 8.098861 8.194487 FAM198B 0.809894509 0.045243682 0.021387547 6.404666456 6.381847 6.044198 6.636262 8.723321 10.843782 9.008063 GOLGA7 0.647396377 0.051665552 0.035478734 6.404198818 5.328526 5.487673 3.90836 8.254907 7.505595 6.587378 LINC00485 0.63730912 0.052514975 0.037026199 6.404198818 1.874444 2.809601 3.90836 4.341916 5.509998 6.587378 MAGEH1 0.618203421 0.054162167 0.039706703 6.403910875 5.263699 2.023048 3.935222 5.448591 7.942653 6.051818 STOML2 0.608674123 0.055179858 0.041182715 6.39949832 6.973646 5.195784 5.217616 8.331873 8.181074 7.873743 IQCB1 0.721798843 0.047650501 0.027759102 6.397463061 5.491121 4.736586 4.754917 7.477873 7.414086 7.640338 PARD3 0.786109028 0.045579058 0.022860157 6.391891713 5.856559 5.195784 5.609945 8.286188 8.033973 8.519314 RWDD4 0.670758881 0.050060495 0.032666213 6.391800305 5.897292 4.389936 2.165421 6.857154 7.066159 7.218312 SERINC1 0.604313082 0.055729438 0.041974141 6.378789812 5.982974 5.487673 5.217616 9.645614 8.160956 6.455366 RRN3 0.698964767 0.048753782 0.029960531 6.372106251 6.143785 5.148082 4.508334 8.540832 8.160956 7.180104 ARL6IP5 0.773147811 0.046036363 0.023842123 6.370982256 6.846868 7.0583 7.519866 10.191381 9.694987 9.642233 RBM8A 0.798449919 0.045355733 0.022102756 6.369318925 7.880509 8.170275 7.762571 10.43065 10.68376 10.841414 PCGF3 0.675805492 0.049779748 0.032118408 6.369173936 6.186289 5.43468 4.724406 8.190235 8.350533 7.395512 SEPN1 0.717131738 0.047840971 0.028158557 6.365120559 6.099991 5.661685 4.508334 8.331873 8.436733 7.611911 PDCD6IP 0.746645602 0.046800775 0.025872746 6.354708396 7.427999 6.849665 6.072169 9.352401 9.608485 9.517491 CHURC1 0.777390157 0.045858846 0.02350051 6.349587244 5.700376 4.389936 5.389265 8.173604 8.055928 7.748756 C6orf89 0.576182123 0.059351075 0.047470568 6.349587244 6.099991 4.911517 5.389265 8.811966 8.055928 6.455366 RPL39L 0.823450169 0.045005314 0.020498809 6.341084581 1.874444 2.023048 2.165421 6.811341 4.539173 4.562324 CEP97 0.804479862 0.045327183 0.021723716 6.341084581 1.874444 2.023048 2.165421 5.705318 4.539173 4.562324 PIP5K1B 0.798401458 0.045355733 0.022109561 6.341048581 1.874444 2.023048 2.165421 4.739845 4.539173 4.790662 WNT4 0.741790999 0.046966189 0.026222525 6.341084581 1.874444 2.809601 2.165421 5.705318 4.539173 4.790662 NOSTRIN 0.659765358 0.050686676 0.033794488 6.341084581 1.874444 3.360637 3.764125 6.067497 4.539173 6.385515 LOC100509894 0.645735625 0.051818705 0.035799932 6.341084581 1.874444 2.406905 3.90836 5.705318 4.539173 5.580533 ARHGAP9 0.57368366 0.059795609 0.048128615 6.341084581 1.874444 2.809601 4.449894 5.743334 4.539173 5.900694 WNT5A 0.566836366 0.060882212 0.049629806 6.341084581 1.874444 2.023048 5.225216 6.544171 4.539173 5.634184 EVI5 0.729239139 0.047411805 0.027154815 6.329201007 6.648293 3.872014 5.544653 8.206677 8.077554 8.650903 PNPLA4 0.648912942 0.051556323 0.035214699 6.322924346 4.263463 4.351315 5.974145 8.105092 7.138979 6.924055 VDR 0.678128041 0.049604445 0.031825791 6.312771171 3.839948 4.911517 5.571599 6.498222 8.160956 7.668215 ZFHX4 0.637630221 0.052501106 0.036971079 6.311461597 5.744513 3.770995 5.592916 6.063041 9.075328 8.25089 ERAP1 0.692048724 0.048955004 0.030493365 6.286061303 4.309025 5.148082 3.935222 7.167419 7.191402 6.587378 ANP32B 0.706956099 0.04829046 0.029101735 6.279094921 7.626325 7.106065 6.636262 9.805293 9.756621 9.33818 SERP1 0.676438867 0.049712169 0.032019735 6.277966306 7.04469 6.391145 7.381261 11.733767 9.694987 8.135789 KLF9 0.63876887 0.05242235 0.036773052 6.270893872 9.955336 8.170275 8.844667 10.98468 11.493339 11.770461 BATF 0.720638274 0.047703746 0.027848928 6.26859894 5.335413 5.340619 5.592916 9.268737 7.269549 7.988762 VANGL1 0.663655344 0.050460138 0.033397074 6.266299509 4.209882 2.809601 2.379345 5.026959 6.205902 5.900694 LOC285593 0.579011342 0.058854512 0.046898945 6.266299509 1.874444 2.023048 2.379345 5.026959 3.134528 4.790662 MTG1 0.589399659 0.05748724 0.044736305 6.254110872 6.306772 4.750708 3.935222 8.105092 6.640994 7.395512 DICER1 0.776695265 0.045858868 0.023579449 6.2531581 6.765086 6.092406 6.072169 9.049264 9.409671 8.705744 THEM4 0.667022298 0.050336605 0.033103096 6.25007546 6.873131 5.195784 5.702912 8.346785 8.71031 8.213534 CARKD 0.707235261 0.048286461 0.029077237 6.248534478 5.779429 4.750708 4.944468 7.394225 7.845161 7.825039 PRMT7 0.756997911 0.046433585 0.025043892 6.245595399 3.819732 4.830496 5.389265 7.394225 7.473335 7.553321 FAM3C 0.668091983 0.050279153 0.032952705 6.233492416 6.52121 6.311907 5.723602 9.4454 8.951948 7.748756 ASTE1 0.667604696 0.050323626 0.033043892 6.226851464 4.263463 2.809601 2.995681 6.498222 5.509998 5.634184 AASS 0.672534726 0.049933984 0.032426676 6.226410414 7.021395 6.35207 6.601009 8.331873 9.933088 9.23941 FGD5 0.576082364 0.059369107 0.047494386 6.221935787 4.682076 2.023048 4.724406 6.183122 5.317867 7.36177 GYLTL1B 0.781499405 0.04575418 0.023214699 6.221206979 2.201691 2.023048 2.165421 4.802615 5.165949 4.476242 MAP4K2 0.68660571 0.049239157 0.030966996 6.221206979 3.350997 2.023048 2.165421 4.802615 4.608763 6.051818 FAM69B 0.605091915 0.055639512 0.041833957 6.221206979 2.993831 4.413323 2.165421 4.802615 5.165949 7.327219 PABPC1P2 0.630421597 0.053156193 0.038004764 6.220177893 1.874444 2.809601 4.285996 5.026959 6.043524 5.446557 NOP10 0.746207029 0.046831501 0.02595985 6.210492173 6.267718 5.789702 5.702912 9.212855 8.160956 8.424409 PGM1 0.599237274 0.05639214 0.042979925 6.205034262 5.304463 4.351315 3.764125 7.937902 7.107836 5.634184 GPD1L 0.810753051 0.045237293 0.021335829 6.200469805 1.874444 2.406905 2.165421 6.960054 4.797798 4.476242 LOC100507632 0.789061705 0.045529634 0.022690031 6.200469805 1.874444 2.023048 2.165421 4.739845 4.797798 4.476242 MMS22L 0.734010545 0.047307334 0.026788704 6.200469805 2.201691 2.023048 2.165421 4.013424 4.797798 5.900694 THAP10 0.725477305 0.047551011 0.027461041 6.200469805 2.201691 2.023048 2.165421 5.095353 4.797798 4.146207 PHGR1 0.679287337 0.049531477 0.031707383 6.200469805 1.874444 2.809601 2.165421 7.243046 4.797798 3.630092 COMMD10 0.631234294 0.053124771 0.0378918 6.200469805 1.874444 2.809601 2.165421 8.239009 4.797798 2.921909 LOC100306975 0.628967889 0.053255542 0.038225927 6.200469805 2.993831 2.023048 2.165421 6.395481 4.797798 3.676349 RAB20 0.623340081 0.053779735 0.038988772 6.200469805 2.201691 2.023048 2.165421 6.811341 4.797798 2.921909 SAMD12 0.622886223 0.053781042 0.039050698 6.200469805 1.874444 2.406905 2.165421 6.960054 4.797798 2.921909 YME1L1 0.707759655 0.048268527 0.029028241 6.200217736 8.183076 7.0583 7.519866 10.538507 10.260704 9.690619 C12orf23 0.586249836 0.05781824 0.045292957 6.197431708 5.491121 4.389936 5.225216 7.856887 8.533804 5.900694 KIAA0430 0.799977127 0.045343942 0.022038108 6.194682883 5.263699 2.809601 5.217616 7.42265 7.89473 7.695565 NR4A3 0.671300675 0.05002854 0.032579789 6.192430988 6.973646 6.391145 7.746525 9.02165 9.198885 10.75629 KAT6B 0.67240424 0.049938578 0.032457979 6.191837919 5.744513 4.389936 5.592916 8.711848 7.819723 7.020304 SH3BP5 0.739196023 0.04712834 0.026457298 6.182635673 6.678389 6.060401 6.704285 8.688623 9.500541 9.113234 PSME4 0.723918014 0.047585406 0.027557673 6.176140084 6.58615 6.03611 5.592916 9.212855 8.486085 8.374509 C10orf137 0.77162679 0.046066162 0.023965975 6.171850359 2.201691 3.770995 3.764125 6.396698 6.189775 5.882028 SLC38A9 0.803247556 0.045338539 0.021835318 6.169874574 2.201691 2.023048 2.165421 5.705318 4.539173 4.790662 LY75 0.746199097 0.046831501 0.025966655 6.169874574 1.874444 2.809601 2.165421 4.718672 5.317867 4.790662 ST3GAL6 0.732745297 0.047310912 0.026903028 6.169874574 1.874444 2.023048 2.165421 4.739845 4.131418 4.790662 SORCS1 0.731293144 0.047384624 0.027029602 6.169874574 1.874444 2.023048 2.165421 4.718672 4.131418 4.790662 ATP6V1G2 0.731293144 0.047384624 0.027029602 6.169874574 1.874444 2.023048 2.165421 4.718672 4.131418 4.790662 ZCCHC7 0.689604371 0.048997321 0.030667574 6.169874574 4.209882 2.406905 2.165421 6.395481 5.936219 4.790662 LOXL4 0.643914313 0.05192151 0.036039469 6.169874574 1.874444 2.023048 2.165421 4.718672 3.571326 4.790662 PDCD10 0.622790976 0.053781042 0.039076557 6.169874574 2.201691 4.80797 2.165421 6.063041 6.189775 4.790662 LRP2 0.613359747 0.054636493 0.040389929 6.169874574 3.024504 5.809601 2.165421 8.033165 6.78473 4.790662 CEP128 0.580950678 0.058713636 0.046551888 6.169874574 1.874444 2.023048 2.165421 4.718672 3.134528 4.790662 SLITRK2 0.580950678 0.058713636 0.046551888 6.169874574 1.874444 2.023048 2.165421 4.718672 3.134528 4.790662 PRR15 0.580950678 0.058713636 0.046551888 6.169874574 1.874444 2.023048 2.165421 4.718672 3.134528 4.790662 MS4A10 0.566973128 0.060860764 0.049593059 6.169874574 1.874444 3.770995 2.165421 4.718672 4.797798 4.790662 HAUS7 0.704638232 0.048398142 0.029365771 6.166945962 1.874444 4.413323 3.935222 7.037879 5.936219 5.900694 UBE2E2 0.646430089 0.051758104 0.035673358 6.165717833 6.099991 4.80797 4.449894 7.074163 8.011679 7.640338 FBXO42 0.672918528 0.049933984 0.03237904 6.153428226 5.056948 4.389936 3.764125 7.074163 7.174648 6.385515 GREM2 0.746388815 0.046811314 0.025929228 6.147729224 1.874444 2.406905 2.995681 5.026959 6.608026 4.476242 TRAPPC4 0.712375839 0.047984994 0.02852671 6.147729224 3.024504 2.406905 2.165421 5.026959 5.920411 4.562324 TRIM35 0.699310759 0.048734593 0.029933311 6.144287498 6.949166 5.661685 6.031658 8.527804 9.128102 8.650903 RAP2A 0.592278803 0.057117807 0.044140864 6.138671976 5.856559 3.32135 5.544653 8.474485 7.767462 6.106561 HSD17B7 0.758373148 0.046395081 0.024941817 6.133154875 2.201691 2.809601 2.379345 5.095353 4.797798 5.426231 PRPF38B 0.722189064 0.047646206 0.027719633 6.130013613 6.417969 6.732825 7.030042 9.733347 9.348715 8.79697 ULK3 0.749973716 0.046675232 0.025610071 6.128218609 4.815804 2.406905 3.935222 6.550689 6.549959 6.931222 UBE2D3 0.713478308 0.047910176 0.02841919 6.122541332 8.028068 7.547799 8.659978 11.633951 10.523584 10.161929 SAAL1 0.576950706 0.059162429 0.047291596 6.112848079 4.309025 2.809601 3.324375 6.954147 5.936219 4.562324 CLPTM1L 0.72293872 0.04762218 0.027653624 6.110404087 5.056948 5.789702 3.764125 7.976765 7.31791 7.668215 NEDD1 0.63932846 0.052350016 0.036669616 6.102397887 3.024504 2.809601 3.764125 6.063041 6.373501 4.562324 MIR3654 0.569651195 0.060367121 0.048971079 6.102397887 3.839948 6.03611 3.764125 7.42265 6.373501 6.73963 GSPT1 0.641873024 0.052014843 0.03627016 6.101961302 6.227577 6.983552 6.282905 11.101397 8.892178 7.695565 USP53 0.73272147 0.047310912 0.026916638 6.100229584 5.491121 6.638536 5.571599 9.08528 9.2474 7.774634 SBNO1 0.68502202 0.04931773 0.031172508 6.096581054 5.856559 5.43468 5.592916 8.579223 8.200916 7.46072 HSPB8 0.707660141 0.048268527 0.029035046 6.094578281 3.839948 5.661685 6.072169 7.450526 8.277663 8.269212 MATR3 0.738742593 0.04712834 0.026496768 6.094130153 7.463005 7.0089 7.884888 10.492308 10.471437 9.478651 CHD1 0.64011702 0.052240009 0.036558013 6.09238336 6.267718 7.440099 8.775186 9.794456 10.047106 10.256805 SETD3 0.722273843 0.047646206 0.027706022 6.092276597 4.209882 4.413323 2.165421 6.395481 6.043524 7.020304 CXorf38 0.686245117 0.049293152 0.031028241 6.080696513 4.209882 4.80797 5.571599 6.814118 8.2398 7.36177 C16orf42 0.726677653 0.047532676 0.027390269 6.073407682 4.639409 3.770995 3.764125 6.339437 6.373501 7.611911 PPP1R3E 0.621803794 0.05388098 0.039241239 6.073407682 4.682076 3.770995 5.702912 7.582358 6.373501 7.492252 XPO6 0.646797371 0.051706895 0.035597142 6.071729159 6.648293 6.466258 5.217616 8.665019 7.819723 9.329475 MYB 0.799367566 0.045351572 0.022062606 6.070427587 1.874444 2.406905 2.379345 8.553743 4.608763 4.476242 MS4A1 0.794188762 0.04542938 0.022395373 6.070427587 1.874444 2.023048 2.165421 5.743334 4.539173 4.476242 LOC100507651 0.791877862 0.045479433 0.022556652 6.070427587 1.874444 2.023048 2.165421 5.252045 4.608763 4.476242 PKHD1 0.791877862 0.045479433 0.022556652 6.070427587 1.874444 2.023048 2.165421 5.252045 4.608763 4.476242 TMEM117 0.785648524 0.045624536 0.02291868 6.070427587 1.874444 2.023048 2.165421 5.026959 4.608763 4.476242 TTC8 0.784940642 0.045655746 0.022985369 6.070427587 1.874444 2.023048 2.165421 5.320955 4.539173 4.476242 LOC100130231 0.783263733 0.045695042 0.023077918 6.070427587 1.874444 2.023048 2.165421 5.252045 4.539173 4.476242 LOC148824 0.772954975 0.046036363 0.023855733 6.070427587 1.874444 2.023048 2.165421 4.894482 4.539173 4.476242 SERPINA5 0.767359794 0.046164489 0.024336169 6.070427587 1.874444 2.406905 2.165421 6.244586 4.539173 4.476242 LOC399708 0.716773255 0.047841399 0.028203471 6.070427587 1.874444 3.32135 2.165421 5.252045 5.857745 4.476242 PLCE1 0.700930208 0.04866899 0.02978428 6.070427587 1.874444 2.023048 3.935222 5.705318 6.205902 4.476242 LOC730102 0.648580539 0.051579258 0.035263015 6.070427587 1.874444 2.023048 4.285996 5.320955 6.608026 4.476242 CREG1 0.622962184 0.053781042 0.039021436 6.06973273 7.6108 5.789702 6.410545 9.388882 9.218487 8.391335 RNF111 0.606547346 0.055460008 0.041578088 6.055809683 4.263463 3.770995 4.508334 5.320955 6.861783 7.46072 PHF3 0.711095397 0.048062795 0.028677101 6.050338806 6.820119 5.362142 6.282905 8.514658 8.87992 8.906373 CROT 0.721799242 0.047650501 0.027752297 6.049691902 5.056948 5.297868 4.508334 7.177844 7.89473 7.46072 NSD1 0.685638365 0.049314432 0.031113984 6.049691902 5.263699 5.297868 3.90836 7.074163 7.89473 7.218312 MTFMT 0.644864473 0.051844669 0.035921742 6.047784881 6.099991 6.184248 5.389265 7.25991 8.696398 9.182543 LOC100507547 0.717768269 0.047825499 0.028125213 6.046530874 2.201691 2.406905 2.165421 5.891233 4.797798 4.146207 AMMECR1 0.712692645 0.047957459 0.028492004 6.046229889 2.993831 2.406905 3.324375 4.802615 5.920411 5.874974 RFC5 0.651676868 0.051348633 0.034869684 6.046229889 4.815804 4.413323 3.324375 7.450526 5.920411 6.722123 TWISTNB 0.720680766 0.047703746 0.027842123 6.039824233 5.856559 5.195784 5.225216 8.665019 7.819723 7.611911 FAM208B 0.698379335 0.048774753 0.030019735 6.034305046 5.263699 5.195784 5.702912 7.856887 8.332658 7.395512 RBM7 0.602306335 0.055983853 0.042340932 6.029656857 4.743564 2.809601 6.282905 7.33564 7.56803 6.649696 RNF19B 0.743501271 0.046889341 0.026097993 6.019084747 5.328526 5.789702 5.592916 7.918071 7.96603 8.60836 LOC728743 0.72890928 0.047423411 0.027201089 6.007240436 2.993831 2.406905 2.379345 5.448591 4.608763 5.580533 TTC39B 0.793923005 0.04542938 0.022406261 6.003132932 1.874444 2.023048 2.165421 4.341916 4.608763 6.195186 FGF14 0.782165744 0.045708444 0.023176591 6.003132932 1.874444 2.023048 2.165421 4.341916 4.608763 5.634184 G6PC2 0.77718423 0.045858868 0.023525009 6.003132932 1.874444 2.023048 2.165421 4.341916 4.608763 5.426231 RMND1 0.774093763 0.046000938 0.023805376 6.003132932 1.874444 2.023048 2.165421 4.739845 4.608763 4.476242 LRRC34 0.774093763 0.046000938 0.023805376 6.003132932 1.874444 2.023048 2.165421 4.739845 4.608763 4.476242 KBTBD3 0.735795927 0.047251954 0.02668867 6.003132932 1.874444 2.023048 2.165421 5.026959 4.608763 4.146207 AMY2B 0.706730325 0.048309794 0.029122831 6.003132932 1.874444 2.023048 2.165421 6.396698 4.608763 3.630092 DPY19L2P1 0.706696085 0.048309794 0.029129636 6.003132932 1.874444 2.023048 2.165421 6.395481 4.608763 3.630092 BBOX1 0.703502776 0.048494719 0.029504593 6.003132932 1.874444 2.023048 2.165421 6.283686 4.608763 3.630092 TOR3A 0.6871121 0.04915291 0.030889418 6.003132932 1.874444 2.023048 2.165421 5.579836 4.608763 3.676349 RALGPS1 0.685158463 0.049314432 0.031154815 6.003132932 1.874444 2.023048 2.165421 5.705318 4.608763 3.630092 FER 0.674172074 0.049879314 0.032269479 6.003132932 3.350997 2.023048 2.165421 5.320955 4.608763 5.091834 TMEM155 0.657802063 0.050866557 0.03406737 6.003132932 1.874444 2.023048 2.165421 4.894482 4.608763 3.676349 FER1L6 0.657549253 0.050890262 0.034099354 6.003132932 1.874444 2.023048 2.165421 5.026959 4.608763 3.630092 SLC35D2 0.648662627 0.051564319 0.035237836 6.003132932 1.874444 2.023048 2.165421 7.30543 4.608763 2.921909 IL12A 0.646078574 0.051811216 0.03574277 6.003132932 1.874444 2.023048 3.324375 5.320955 4.608763 4.562324 MSTO2P 0.645893653 0.05181797 0.035778836 6.003132932 1.874444 2.023048 2.165421 4.802615 4.608763 3.630092 HSP90AB4P 0.645893653 0.05181797 0.035778836 6.003132932 1.874444 2.023048 2.165421 4.802615 4.608763 3.630092 NMNAT3 0.613271733 0.054662138 0.040434842 6.003132932 1.874444 2.023048 2.165421 6.244586 4.608763 2.921909 GRTP1 0.611635505 0.054824023 0.040630827 6.003132932 4.815804 2.023048 2.165421 6.339437 4.608763 5.900694 LYPD6 0.610938485 0.054913436 0.040749234 6.003132932 1.874444 2.023048 2.165421 6.183122 4.608763 2.921909 C1orf168 0.606446728 0.055460008 0.041584893 6.003132932 1.874444 2.023048 2.165421 6.067497 4.608763 2.921909 DYX1C1 0.599324182 0.056384204 0.042964954 6.003132932 1.874444 2.023048 2.165421 5.891233 4.608763 2.921909 HS6ST2 0.596655057 0.056634604 0.043390949 6.003132932 1.874444 2.023048 2.379345 6.283686 4.608763 2.921909 C15orf41 0.593068783 0.057053082 0.04397346 6.003132932 1.874444 2.023048 2.165421 5.743334 4.608763 2.921909 NEK11 0.591416681 0.057236297 0.044338891 6.003132932 1.874444 2.023048 2.165421 5.705318 4.608763 2.921909 UGT2B15 0.591416681 0.057236297 0.044338891 6.003132932 1.874444 2.023048 2.165421 5.705318 4.608763 2.921909 RGS22 0.586043541 0.057869242 0.045371895 6.003132932 1.874444 2.023048 2.165421 2.820813 4.608763 5.874974 GPR137C 0.585826717 0.057927026 0.045451514 6.003132932 1.874444 2.023048 2.165421 5.579836 4.608763 2.921909 TEX11 0.579740941 0.058818437 0.046805036 6.003132932 1.874444 2.023048 2.165421 5.448591 4.608763 2.921909 ZNF174 0.573567715 0.059795609 0.048145628 6.003132932 1.874444 2.023048 2.165421 5.320955 4.608763 2.921909 STX19 0.573567715 0.059795609 0.048145628 6.003132932 1.874444 2.023048 2.165421 5.320955 4.608763 2.921909 JAKMIP3 0.570122628 0.06033194 0.048881252 6.003132932 1.874444 2.023048 2.165421 5.252045 4.608763 2.921909 MORN4 0.716966686 0.047841399 0.028183055 6.001082393 3.350997 2.809601 2.379345 4.718672 5.936219 5.874974 SCMH1 0.682122182 0.049418096 0.031456958 6.001082393 3.350997 3.32135 2.165421 4.894482 5.936219 5.634184 IDH1 0.628930644 0.053255542 0.038239537 6.001082393 3.350997 2.809601 4.754917 7.074163 5.936219 5.426231 PSRC1 0.594989078 0.056818692 0.043610752 5.999541211 1.874444 2.023048 2.995681 4.718672 3.571326 5.580533 MYCL1 0.570018369 0.06033194 0.048916638 5.999541211 1.874444 3.32135 2.995681 6.067497 3.571326 5.580533 CALM1 0.725328255 0.047551011 0.027474651 5.997499245 8.705736 8.288855 9.015087 10.873216 11.373865 11.373125 GYPC 0.565125401 0.061148989 0.049953726 5.992474504 7.218633 4.830496 5.544653 7.556937 7.473335 9.801784 SRSF3 0.695567999 0.048858998 0.030239537 5.992052519 9.071674 8.288855 8.089553 11.341819 10.871906 10.713441 SLC19A2 0.713100849 0.047923769 0.028448452 5.98572237 7.04469 6.184248 7.462086 10.043611 9.1177 9.430619 RDX 0.714447662 0.047892936 0.028369513 5.983644174 6.008206 4.830496 4.724406 7.30543 7.91889 8.357484 LOC100129361 0.784601478 0.045655746 0.022998979 5.979009001 4.682076 4.351315 2.995681 7.167419 6.774676 6.931222 IGSF8 0.691075165 0.048955004 0.030579109 5.976678835 4.963444 3.32135 3.764125 6.960054 7.191402 5.900694 HDDC3 0.624785838 0.053620377 0.03879687 5.976678835 4.815804 3.32135 2.379345 7.25991 5.165949 5.900694 PLA2G15 0.61080131 0.054914277 0.040771011 5.976678835 4.209882 3.32135 2.379345 5.095353 5.920411 5.900694 AP4B1 0.728947163 0.047423411 0.027187479 5.971353843 5.753024 5.148082 5.609945 7.726141 7.989035 8.488368 CLK1 0.67499159 0.04982684 0.032180333 5.969034457 8.467946 8.407985 9.44112 11.922288 12.018618 10.256805 RAB27A 0.747093406 0.046789913 0.025835318 5.966471036 6.099991 5.340619 5.609945 8.676869 8.140553 8.11568 NSUN4 0.685861268 0.049293152 0.031066349 5.96495681 5.700376 4.750708 4.449894 7.30543 7.740604 7.327219 SNAP47 0.697199462 0.04881728 0.030123171 5.9641631 3.024504 2.023048 3.324375 4.894482 5.353925 5.900694 ARHGAP12 0.675983849 0.049752474 0.032085063 5.961115945 3.819732 3.360637 2.165421 7.531061 5.936219 4.476242 AJUBA 0.699902104 0.048716465 0.029860497 5.960002356 3.024504 3.872014 3.764125 6.339437 6.613395 5.426231 LSG1 0.693405707 0.048932925 0.030387207 5.959425446 6.099991 6.732825 7.003286 8.875048 9.578459 8.84662 C5orf38 0.738526765 0.047133227 0.026517183 5.956333696 3.024504 2.406905 2.165421 4.739845 5.306419 5.446557 WDR65 0.698410727 0.048774753 0.03001293 5.956333696 2.201691 2.023048 2.165421 4.739845 6.613395 3.630092 LGR6 0.67787504 0.049640889 0.031879551 5.956333696 1.874444 2.809601 2.165421 4.739845 5.509998 4.146207 TAF12 0.677000267 0.049712169 0.031965294 5.956333696 4.209882 3.360637 2.165421 4.739845 6.608026 6.722123 AQP7P1 0.65932558 0.050730781 0.033872065 5.956333696 2.201691 2.023048 2.165421 4.739845 5.317867 3.676349 EIF2S1 0.767368281 0.046164489 0.024329364 5.95344287 5.658609 6.03611 4.724406 8.014609 8.579995 8.232333 CPSF1 0.689489128 0.049009935 0.030683226 5.952291484 6.054828 6.792427 6.410545 8.98399 8.200916 9.808064 LSM3 0.697295217 0.04880813 0.030108881 5.950901869 5.304463 2.809601 3.324375 7.877571 7.656894 5.106393 CLASP2 0.665584368 0.050369816 0.033208574 5.945003372 4.815804 5.195784 5.225216 6.814118 7.767462 7.800057 PDP1 0.771021059 0.04607418 0.024033345 5.942861897 3.839948 4.389936 4.285996 6.857154 6.640994 6.924055 LOC253039 0.638100126 0.05248745 0.036913916 5.938510303 6.381847 5.340619 5.571599 7.33564 8.951948 8.269212 SLC37A4 0.673725749 0.049906853 0.03231099 5.937611447 3.024504 3.32135 2.165421 5.891233 5.306419 4.790662 C5orf35 0.604699334 0.055669574 0.0418918 5.937611447 3.350997 3.32135 5.389265 5.891233 6.774676 6.587378 MCTP1 0.603258657 0.055835227 0.042122491 5.937611447 1.874444 3.32135 3.935222 5.891233 4.131418 6.722123 DDX20 0.654901491 0.051064299 0.034406941 5.935682232 3.350997 4.351315 2.995681 6.396698 5.920411 5.634184 PADI2 0.629013999 0.053255542 0.038212317 5.926589534 4.263463 4.750708 4.944468 7.556937 7.31791 6.106561 NOV 0.757520231 0.046414887 0.024990813 5.925177523 2.993831 3.360637 3.324375 5.891233 5.306419 6.931222 LTF 0.590651369 0.057323276 0.044460701 5.920761027 3.819732 8.028729 3.90836 10.170577 8.055928 6.385515 TRIM68 0.678975193 0.049548437 0.031733923 5.914231015 5.491121 3.770995 5.571599 7.167419 7.440337 8.135789 MSH6 0.676849013 0.049712169 0.031999319 5.905854793 4.263463 2.809601 3.764125 5.320955 7.107836 6.32627 ARSD 0.703348717 0.048494719 0.029525009 5.904513307 6.186289 4.911517 3.90836 8.676869 7.473335 7.327219 APOM 0.727491772 0.047495226 0.02733719 5.899846122 2.993831 3.32135 2.379345 5.448591 5.165949 5.882028 MAGT1 0.63896869 0.052399012 0.036735624 5.892189698 6.648293 5.661685 5.018694 8.376156 8.220489 7.873743 USP9X 0.77674678 0.045858868 0.023572644 5.887554248 6.554045 6.605686 6.800663 9.111713 9.158864 9.656224 TIMM8B 0.696031416 0.048858998 0.030210276 5.887491283 3.819732 4.389936 3.324375 6.283686 7.094585 5.882028 SAP 18 0.703615866 0.048494719 0.029490983 5.879949428 7.6108 6.702075 7.295639 10.388031 9.673843 9.257878 LOC100289019 0.58964562 0.057478449 0.044694794 5.878842455 3.839948 2.809601 2.165421 6.395481 4.131418 5.446557 SLC16A1 0.632110702 0.05307838 0.037811501 5.87802434 3.024504 2.023048 4.754917 5.579836 6.549959 5.446557 ZNF721 0.600240025 0.056344664 0.042805716 5.87802434 3.024504 4.389936 3.90836 5.579836 7.174648 5.580533 SLC4A5 0.677629479 0.04967045 0.031914257 5.876079703 7.427999 7.174872 7.360327 8.915622 9.915181 10.8322 GTDC1 0.655353963 0.051064299 0.034350459 5.871660196 3.819732 2.023048 2.379345 5.743334 6.373501 4.146207 LOC285540 0.682575999 0.04941326 0.031423613 5.869556561 1.874444 2.406905 2.165421 4.718672 6.373501 3.630092 IRAK4 0.659207363 0.050733231 0.033889758 5.869556561 3.350997 3.32135 2.165421 4.718672 6.205902 5.446557 GOLGA7B 0.648040779 0.051631895 0.035365771 5.869556561 1.874444 2.023048 2.165421 4.718672 4.608763 3.676349 PHF19 0.730920509 0.047384624 0.02705342 5.858774494 3.819732 2.023048 3.324375 5.448591 6.189775 5.874974 PDE3B 0.717854869 0.0478155 0.028096632 5.858774494 1.874444 2.023048 3.324375 5.728038 4.131418 5.874974 MPV17 0.644316027 0.051909408 0.035981626 5.858774494 5.328526 4.413323 3.324375 7.814607 7.191402 5.874974 MYO5A 0.635568338 0.05262489 0.037211977 5.858774494 4.682076 4.750708 3.324375 7.835902 6.608026 5.874974 PDLIM5 0.641856744 0.052014843 0.036276965 5.856813917 7.530567 6.904719 6.369239 10.09751 8.549366 9.454835 YAP1 0.579821576 0.05881361 0.046782579 5.856245611 7.021395 6.572071 6.800663 9.571371 9.47632 7.920856 PDK3 0.658664765 0.050764584 0.033929228 5.852465898 5.328526 3.770995 5.225216 7.877571 6.78473 7.218312 SLC25A32 0.598012329 0.056497546 0.043185437 5.852124624 4.743564 4.413323 2.165421 5.026959 7.292524 6.69026 MICAL1 0.777688262 0.045844227 0.023484859 5.849343305 3.819732 3.770995 3.764125 6.067497 6.319269 7.640338 EEPD1 0.59251198 0.057110241 0.044089826 5.849343305 3.839948 3.770995 3.764125 5.026959 6.319269 6.649696 C14orf105 0.732192824 0.047339553 0.026977884 5.844202729 4.209882 3.32135 3.90836 6.498222 6.189775 6.455366 PBRM1 0.630499357 0.053156193 0.037997958 5.844202729 5.316227 3.32135 3.90836 6.252746 7.187136 6.455366 IFI44L 0.654697141 0.051064299 0.034434161 5.838819305 5.316227 4.389936 5.609945 7.274575 7.174648 8.155622 NUAK1 0.775659009 0.045918659 0.023704661 5.838702945 6.846868 2.023048 7.519866 9.466036 9.392516 9.08248 TBC1D23 0.683988787 0.049364239 0.031280027 5.838252633 6.008206 4.80797 4.724406 8.553743 7.656894 7.152205 ANP32E 0.673464155 0.049917775 0.032325961 5.828821825 5.753024 4.830496 6.175931 8.301578 8.296229 7.611911 SAP30 0.634836195 0.05273953 0.037358285 5.823218787 3.350997 4.750708 6.072169 8.566539 7.292524 6.385515 TDG 0.71506089 0.047877006 0.028298061 5.821197424 5.056948 5.661685 4.754917 8.688623 7.598264 7.218312 BBS10 0.626933241 0.053471909 0.038511739 5.816843156 3.350997 4.413323 2.379345 5.891233 6.613395 5.091834 KLHL17 0.662920968 0.050504642 0.033471249 5.816121601 2.993831 3.360637 2.165421 5.579836 4.539173 5.900694 TROAP 0.768799847 0.046108296 0.024150391 5.81297314 1.874444 2.023048 2.165421 4.341916 5.306419 4.562324 SAMD7 0.764944169 0.046181862 0.024492004 5.81297314 1.874444 2.023048 2.165421 4.341916 5.165949 4.562324 CLEC4A 0.76265668 0.046311565 0.024706363 5.81297314 1.874444 2.023048 2.165421 6.244586 4.131418 4.562324 GRIA4 0.746521389 0.046800775 0.025886356 5.81297314 1.874444 2.023048 2.165421 4.013424 6.205902 4.562324 ABCC8 0.719357866 0.047758583 0.028002722 5.81297314 1.874444 2.023048 2.165421 7.33564 3.571326 4.562324 LOC730091 0.716660504 0.047853797 0.028225927 5.81297314 1.874444 2.023048 2.165421 4.739845 4.131418 4.562324 MS4A6A 0.685401815 0.049314432 0.031127594 5.81297314 3.024504 2.023048 2.379345 5.579836 4.797798 4.562324 TAG 0.679408784 0.049531477 0.031693773 5.81297314 1.874444 2.023048 2.165421 5.891233 3.571326 4.562324 CGA 0.676103313 0.049736329 0.032051038 5.81297314 2.993831 2.023048 2.165421 4.718672 5.165949 4.562324 MED7 0.652242397 0.051304265 0.034800272 5.81297314 3.024504 2.023048 2.165421 4.802615 4.797798 4.562324 PGF 0.64601953 0.05181797 0.035768629 5.81297314 4.263463 2.023048 2.165421 5.252045 6.794431 4.562324 ZNF707 0.645285504 0.051831344 0.035846887 5.81297314 1.874444 2.023048 2.165421 5.026959 3.571326 4.562324 AIMP2 0.638675212 0.052436705 0.036811841 5.81297314 1.874444 2.023048 2.165421 4.894482 3.571326 4.562324 ENO4 0.633763146 0.052882301 0.037512759 5.81297314 1.874444 2.023048 2.165421 4.802615 3.571326 4.562324 EXTL2 0.617259269 0.054254364 0.039908132 5.81297314 1.874444 2.023048 2.165421 2.820813 6.794431 4.562324 PDE6B 0.604054866 0.055744926 0.042027901 5.81297314 1.874444 2.023048 2.165421 5.448591 3.134528 4.562324 PDCD1LG2 0.595270371 0.056763192 0.043550187 5.81297314 1.874444 2.023048 2.165421 2.820813 6.189775 4.562324 CASC1 0.587139369 0.057666624 0.045112623 5.81297314 1.874444 2.023048 2.165421 5.095353 3.134528 4.562324 ZNF385D 0.662126017 0.050577128 0.033602586 5.808455927 2.201691 2.406905 3.90836 4.739845 5.353925 6.195186 CENPC1 0.617023127 0.054286282 0.039965975 5.797792991 3.819732 3.872014 4.724406 7.25991 6.608026 5.580533 PRPF4B 0.682997823 0.049394421 0.031354883 5.794615067 6.678389 6.311907 7.7303 9.739011 9.834907 8.84662 NUP43 0.597896082 0.056511538 0.043214018 5.794270306 4.682076 3.872014 5.018694 5.728038 7.269549 7.553321 C7orf70 0.646792008 0.051706895 0.035603947 5.789955904 3.839948 2.023048 2.995681 5.320955 6.373501 4.790662 PSME1 0.579136251 0.058839456 0.046875128 5.787354991 8.977969 7.530398 7.295639 10.207812 9.828543 10.328455 GPSM3 0.756359649 0.0464784 0.025133719 5.778103718 3.819732 3.360637 3.764125 5.891233 6.189775 7.03218 LOC100628307 0.599759933 0.056344664 0.042872406 5.774356979 4.209882 4.413323 4.724406 5.728038 7.440337 6.942983 CLEC4E 0.608261984 0.055202948 0.041217421 5.769454624 6.554045 4.351315 8.199725 8.433162 9.608485 9.08248 KCTD7 0.74996402 0.046675232 0.025616876 5.763485537 5.658609 5.43468 5.592916 7.748771 8.119857 8.771488 BDP1 0.621328735 0.053905072 0.039303164 5.759666814 4.743564 4.736586 5.702912 8.41912 7.269549 6.649696 MTMR11 0.749396644 0.04671806 0.025663151 5.75764856 4.743564 2.406905 4.508334 6.396698 7.25505 7.033813 SLC22A15 0.703130467 0.048515004 0.02955359 5.751654222 3.350997 2.406905 2.165421 5.448591 4.539173 5.874974 OTX2OS1 0.613854736 0.054598842 0.040342974 5.750506093 4.682076 4.830496 5.571599 6.395481 7.598264 8.095288 GNPTAB 0.61754354 0.054225734 0.039830555 5.749911688 6.381847 4.80797 5.225216 7.70315 7.819723 7.748756 SPTAN1 0.635954497 0.052606547 0.037165703 5.744015408 5.779429 4.830496 6.355801 8.974419 8.033973 7.352555 ATG4C 0.648594687 0.051564319 0.035244641 5.741352919 4.682076 3.360637 3.764125 6.811341 6.319269 5.882028 SSH3 0.696766505 0.048824537 0.030165362 5.736395398 1.874444 3.770995 3.935222 5.448591 5.936219 6.455366 RSF1 0.648542826 0.051584246 0.035277305 5.731640456 6.008206 4.736586 5.225216 7.995811 7.845161 7.255535 LOC100506123 0.680184513 0.049490097 0.031611432 5.731532735 5.658609 7.581983 6.601009 8.700282 10.100904 9.051056 UBE2B 0.693641309 0.048932925 0.030373596 5.730329324 8.096549 7.726519 8.448127 11.282943 10.615167 9.984774 INTU 0.623652848 0.053749228 0.038941136 5.729036137 2.993831 5.789702 6.489771 6.811341 7.819723 9.008063 NPC2 0.71182688 0.048009392 0.028598843 5.728018429 6.554045 6.904719 7.204614 9.252991 9.909162 9.072081 TRIM2 0.615372178 0.05441792 0.040123171 5.727474014 5.982974 4.413323 4.449894 7.631894 7.269549 6.931222 AEBP2 0.613147741 0.054662138 0.040441647 5.726717113 5.056948 6.537655 6.031658 9.252991 8.549366 7.152205 TBC1D9 0.733603476 0.047307334 0.026822729 5.725701724 5.779429 5.195784 5.723602 9.012327 7.713236 8.03232 MANSC4 0.628223788 0.053354225 0.038362708 5.723833206 2.201691 2.023048 2.379345 4.718672 3.571326 5.446557 C7orf31 0.617147803 0.054283162 0.039955087 5.723833206 2.201691 2.023048 3.324375 4.718672 4.131418 5.900694 APBA2 0.622468819 0.053781042 0.039117387 5.720601948 2.993831 2.023048 3.935222 7.33564 5.509998 4.146207 TACR1 0.720431747 0.047703746 0.027889758 5.720436921 1.874444 2.023048 2.165421 6.954147 4.539173 3.676349 RXFP1 0.717039206 0.047840971 0.028165362 5.720436921 1.874444 2.023048 2.165421 4.739845 4.539173 4.146207 GTPBP8 0.695921817 0.048858998 0.030225927 5.720436921 1.874444 2.023048 2.165421 6.244586 4.539173 3.630092 ZEB1-AS1 0.685925214 0.049293152 0.031052739 5.720436921 1.874444 2.023048 2.165421 5.728038 4.539173 3.676349 CEP170P1 0.669646167 0.050087347 0.03273018 5.720436921 1.874444 2.023048 2.165421 5.448591 4.539173 3.630092 GPR160 0.664700217 0.050400851 0.033309969 5.720436921 1.874444 2.023048 2.165421 8.087444 4.539173 2.921909 ITGA8 0.658150718 0.050826016 0.034 5.720436921 1.874444 2.023048 2.379345 5.705318 4.539173 3.630092 LOC653786 0.65341886 0.051215566 0.034603607 5.720436921 1.874444 2.023048 2.379345 5.579836 4.539173 3.630092 FIGN 0.652448255 0.051266842 0.034749234 5.720436921 1.874444 2.023048 2.165421 4.894482 4.539173 3.676349 SCLT1 0.652448255 0.051266842 0.034749234 5.720436921 1.874444 2.023048 2.165421 4.894482 4.539173 3.676349 WFDC1 0.645575962 0.051818705 0.035820347 5.720436921 1.874444 2.023048 2.165421 4.894482 4.539173 3.630092 PMS2P5 0.643975023 0.05192151 0.036032664 5.720436921 3.350997 2.023048 2.165421 5.026959 4.539173 5.091834 LOC100128822 0.640787097 0.052144602 0.036433481 5.720436921 1.874444 2.023048 2.165421 4.802615 4.539173 3.630092 HRASLS5 0.60918499 0.055155203 0.041111943 5.720436921 1.874444 2.023048 2.165421 6.283686 4.539173 2.921909 C10orf90 0.607727238 0.05527432 0.041342634 5.720436921 1.874444 2.023048 2.165421 6.244586 4.539173 2.921909 EIF2C3 0.60540701 0.055614955 0.04179789 5.720436921 1.874444 2.023048 2.165421 6.183122 4.539173 2.921909 UBE2T 0.600943485 0.05625006 0.042666894 5.720436921 1.874444 2.023048 2.165421 6.067497 4.539173 2.921909 MAGEB3 0.593874258 0.056998407 0.043829874 5.720436921 1.874444 2.023048 2.165421 5.891233 4.539173 2.921909 CDT1 0.58767426 0.057633938 0.045032324 5.720436921 1.874444 2.023048 2.165421 5.743334 4.539173 2.921909 FLJ39080 0.586038106 0.057869242 0.0453787 5.720436921 1.874444 2.023048 2.165421 5.705318 4.539173 2.921909 RRM2 0.568394348 0.060588284 0.049294318 5.720436921 1.874444 2.023048 2.165421 5.320955 4.539173 2.921909 MIR137HG 0.564995203 0.061169439 0.049989792 5.720436921 1.874444 2.023048 2.165421 5.252045 4.539173 2.921909 CDH6 0.582697999 0.058324851 0.046095951 5.716520629 4.743564 2.809601 2.379345 4.894482 5.353925 7.033813 CMTM8 0.64714969 0.05166843 0.035529772 5.713270096 3.350997 4.750708 2.995681 7.243046 5.509998 6.051818 NEK4 0.63296368 0.052996828 0.037693093 5.713270096 3.839948 3.872014 2.995681 6.498222 5.509998 5.634184 DNAJB9 0.638223427 0.052467325 0.036884655 5.710040895 5.744513 3.872014 5.389265 8.98399 7.627877 6.385515 SLC25A5 0.741498962 0.046993264 0.026253147 5.709164592 8.224469 8.379112 8.26876 11.374934 10.487684 10.78204 KCNE3 0.61041224 0.055028265 0.040886696 5.708924963 6.054828 5.809601 4.944468 6.857154 8.764653 8.32282 NAB2 0.658024396 0.050866557 0.034046955 5.701547947 1.874444 2.809601 4.724406 5.320955 5.317867 7.218312 SLC12A9 0.704407672 0.048408779 0.029380742 5.700992657 4.263463 3.872014 2.165421 6.244586 6.774676 5.634184 RPL13AP3 0.667818478 0.050279153 0.032990813 5.694030585 10.746681 11.243094 10.991078 13.752544 12.804939 13.534412 HDAC2 0.728960958 0.047423411 0.027180674 5.689385347 6.949166 6.184248 6.489771 9.452312 8.998044 8.858771 NIPBL 0.713814769 0.047910176 0.02839197 5.689385347 6.267718 6.391145 6.489771 8.488001 8.998044 8.952456 NDUFB1 0.660656657 0.050667775 0.033725757 5.689355664 1.874444 2.809601 3.324375 5.728038 5.317867 4.476242 TTC31 0.670700714 0.050060495 0.032673018 5.683374834 3.350997 2.023048 2.995681 4.894482 5.857745 5.106393 PTPN12 0.723992986 0.047585406 0.027550868 5.682983595 6.554045 6.072636 6.564874 9.47285 8.829823 8.579284 AKIRIN1 0.695555547 0.048858998 0.030259952 5.682969265 6.58615 6.702075 6.800663 8.566539 9.20872 9.814317 CSNK1G1 0.711384891 0.048031846 0.028627424 5.676861469 4.309025 2.809601 5.217616 6.814118 7.414086 6.587378 GPBP1 0.732958879 0.047310912 0.026896223 5.667534511 7.355332 7.383076 8.114773 10.617494 10.329923 9.776388 RNF8 0.684755574 0.049319443 0.031197006 5.665116747 4.815804 5.43468 4.285996 7.210813 7.31791 7.327219 TFCP2 0.738047111 0.047140798 0.026546444 5.662687565 4.639409 3.872014 2.165421 6.954147 6.373501 6.195186 NIT2 0.732584071 0.047319258 0.026938414 5.660354322 5.316227 6.270596 6.031658 8.270632 8.385634 8.771488 RARS2 0.644139643 0.05192151 0.036019054 5.655038827 3.819732 2.023048 3.764125 4.894482 6.319269 6.051818 MARCH9 0.635884078 0.052606547 0.037172508 5.651889726 3.350997 5.340619 4.285996 6.252746 6.78473 7.352555 NXNL2 0.691951187 0.048955004 0.030511058 5.651565974 7.177073 6.184248 6.83141 9.33006 10.29342 8.503924 DNAJC16 0.748481951 0.046757859 0.025751616 5.64690479 4.639409 4.80797 2.995681 7.30543 7.107836 6.649696 APAF1 0.662945673 0.050504642 0.033464444 5.64690479 5.335413 4.80797 5.596986 7.30543 7.406567 8.155622 ANKRD28 0.679511578 0.049531477 0.031680163 5.643671184 5.304463 6.044198 4.944468 8.540832 8.033973 7.291822 ZDHHC3 0.645166544 0.051833045 0.035875468 5.629821346 5.856559 4.830496 4.449894 7.918071 7.505595 6.942983 ZCCHC8 0.640335197 0.052233632 0.036528751 5.615311659 5.304463 4.736586 4.944468 7.531061 7.793829 6.618407 APC 0.617971238 0.054171819 0.039735965 5.612640492 5.328526 3.872014 4.285996 6.814118 6.774676 6.69026 CD53 0.711335106 0.048031846 0.028634229 5.611988491 4.743564 2.023048 5.544653 8.033165 7.187136 6.455366 SCD5 0.670428918 0.050060495 0.032679823 5.610499142 5.328526 5.43468 4.754917 7.243046 8.277663 7.291822 ING1 0.633169979 0.052977658 0.037654304 5.60839943 6.898923 6.092406 6.054038 8.069577 8.579995 9.462817 KLHDC5 0.755305796 0.046505334 0.02523035 5.607719226 5.304463 4.830496 2.165421 7.33564 7.31791 7.180104 DMAP1 0.606246624 0.055476612 0.041616876 5.607456519 6.48761 6.072636 2.995681 7.274575 7.414086 8.974957 FBXO9 0.695826786 0.048858998 0.030232732 5.606612853 7.021395 7.34377 6.769247 9.058353 9.508524 9.945435 TAGLN2 0.661080494 0.050645852 0.033695134 5.60037725 9.110831 8.436292 8.37695 10.557862 10.935471 11.596355 C9orf156 0.638714067 0.05242235 0.036786662 5.599919931 4.309025 2.023048 3.935222 5.026959 6.794431 6.32627 RALGAPA1 0.663460377 0.05046582 0.033416808 5.596939773 4.263463 5.195784 5.592916 7.36523 8.077554 7.03218 ADH5 0.571992204 0.060047609 0.048474311 5.582574586 7.701538 5.789702 4.285996 8.270632 9.168974 7.722406 XIAP 0.757223896 0.046424242 0.025030963 5.578845229 6.765086 6.670655 5.609945 9.245052 9.086038 8.918033 CTBP2 0.600035518 0.056344664 0.042830214 5.575509776 5.304463 5.340619 5.544658 8.527804 7.819723 6.649696 SSR4 0.643796313 0.05192151 0.036057162 5.572491024 8.646058 7.494953 6.919905 9.973276 9.956624 10.384159 SEPT8 0.626325172 0.053505098 0.038628785 5.569312009 6.52121 4.830496 5.609945 8.087444 7.767462 8.11568 DNAJC10 0.628946276 0.053255542 0.038232732 5.566485664 5.316227 4.830496 4.724406 7.792994 7.56803 6.455366 KRR1 0.623434717 0.053779735 0.038975162 5.564173424 4.263463 5.661685 5.544653 8.447068 7.56803 6.73963 MRPS27 0.667757184 0.050304351 0.033022116 5.562389604 4.309025 5.297868 2.379345 6.283686 6.78473 7.180104 BTF3 0.626472148 0.053505098 0.038597482 5.556441045 3.024504 3.360637 4.449894 5.320955 5.857745 6.924055 ELF2 0.704909472 0.048378239 0.029315413 5.556256441 5.056948 4.750708 5.544653 7.531061 7.870158 7.36177 MRPL47 0.708855224 0.04824159 0.028898265 5.554248025 4.263463 3.770995 3.324375 6.244586 6.373501 6.195186 VPS13A 0.675577189 0.049794345 0.032136781 5.547533404 3.024504 4.389936 3.324375 6.183122 6.861783 5.426231 OSBP 0.718653653 0.047781016 0.02805444 5.53131159 5.335413 3.872014 5.389265 7.856887 7.627877 7.218312 USP49 0.643827528 0.05192151 0.036050357 5.531245015 5.982974 4.750708 3.324375 6.857154 7.793829 7.218312 C8orf37 0.786698111 0.045564387 0.022829534 5.530741745 1.874444 2.023048 2.165421 4.341916 6.613395 4.476242 CREBL2 0.633131893 0.052977658 0.037661109 5.529884629 4.743564 4.413323 6.072169 7.210813 8.36819 7.03218 DENND1B 0.649160617 0.05155431 0.035190201 5.528914934 4.209882 5.487673 4.724406 6.857154 7.191402 7.46072 RBMS2 0.627368315 0.053451936 0.038480436 5.527416111 5.982974 4.80797 6.369239 7.274575 8.350533 8.858771 MDH2 0.679327644 0.049531477 0.031700578 5.524372636 7.992569 7.711156 6.861515 10.45838 9.601037 9.945435 MLLT3 0.636669322 0.052568146 0.037103777 5.523761898 4.309025 3.32135 5.389265 6.814118 6.774676 6.73963 CCDC88A 0.69268385 0.048944238 0.030434842 5.515128831 3.024504 4.750708 4.754917 6.244586 7.138979 7.218312 AHCYL1 0.712229372 0.047984994 0.028547125 5.513438848 7.6108 6.184248 7.611303 9.52623 10.074256 9.776388 FOXO3 0.642279538 0.051978194 0.036210276 5.512563395 7.744853 6.670655 8.024505 9.98762 10.735699 9.133378 DCAF16 0.699860663 0.048730157 0.029884314 5.51204557 5.658609 6.060401 5.974145 7.70315 8.436733 9.389334 PRKD3 0.639457533 0.052350016 0.03666281 5.511224544 4.815804 5.43468 6.072169 6.811341 8.453372 8.534542 LOC100289495 0.672661232 0.049933984 0.032406261 5.50983934 4.963444 4.830496 6.056062 7.109557 8.518072 7.873743 PPIL3 0.723276503 0.04762218 0.027633209 5.509061175 5.658609 6.270596 5.702912 8.566539 7.989035 8.732403 TACC2 0.658064146 0.050858744 0.034029942 5.508192901 5.056948 4.80797 4.285996 8.885299 7.269549 6.051818 PARP8 0.705630956 0.048360255 0.029267098 5.504286553 5.744513 6.228068 6.527811 8.688623 8.36819 8.84662 CCDC90A 0.746900968 0.046798828 0.025855053 5.502639651 5.056948 2.809601 5.225216 7.167419 7.68534 7.255535 IRF1 0.597495528 0.056551179 0.043264376 5.495128386 6.997718 7.87177 8.960487 10.362575 10.329923 9.968046 MTR 0.740357688 0.047053425 0.026345696 5.494089614 6.306772 3.32135 6.175931 8.239009 8.764653 8.175185 QDPR 0.720472503 0.047703746 0.027876148 5.48243198 4.309025 4.736586 4.944468 8.173604 7.191402 6.649696 C2orf28 0.643115734 0.051942518 0.036136101 5.482271165 6.227577 5.362142 3.90836 7.477873 8.682351 7.152205 MKI67IP 0.649636931 0.0515003 0.03509493 5.47824303 5.491121 4.911517 4.508334 7.36523 7.406567 7.033813 ZNF148 0.664336323 0.050408343 0.033329704 5.47794164 4.963444 3.872014 4.285996 6.067497 8.098861 6.73963 PAX8 0.751976242 0.0466011 0.025495066 5.476271078 1.874444 2.023048 2.165421 6.183122 4.131418 4.476242 SASS6 0.749312681 0.046728791 0.025699217 5.476271078 1.874444 2.023048 2.165421 6.067497 4.131418 4.476242 LOC646471 0.733555618 0.047307334 0.026839741 5.476271078 1.874444 2.023048 2.165421 5.448591 4.131418 4.476242 MDH1B 0.733555618 0.047307334 0.026839741 5.476271078 1.874444 2.023048 2.165421 5.448591 4.131418 4.476242 CLDN19 0.733386172 0.047307334 0.026856754 5.476271078 2.201691 2.023048 2.379345 5.095353 4.608763 4.476242 UCP3 0.708091975 0.048268527 0.028987411 5.476271078 1.874444 2.023048 2.165421 4.013424 5.165949 4.476242 SNORD81 0.685408689 0.049314432 0.031120789 5.476271078 1.874444 2.023048 2.165421 6.339437 3.571326 4.476242 GLYATL1 0.655916457 0.050993826 0.034268118 5.476271078 1.874444 2.023048 2.165421 5.448591 3.571326 4.476242 CRISP1 0.648118744 0.051631895 0.035358966 5.476271078 1.874444 2.023048 2.165421 5.252045 3.571326 4.476242 CD1A 0.638302053 0.052467325 0.036871045 5.476271078 1.874444 2.023048 2.165421 5.026959 3.571326 4.476242 CDKL3 0.622732848 0.053781042 0.039083362 5.476271078 1.874444 2.023048 2.165421 4.718672 3.571326 4.476242 ACOX2 0.615061766 0.054502508 0.040195985 5.476271078 2.201691 2.023048 4.724406 5.448591 7.138979 4.476242 WDR5B 0.611120033 0.054867364 0.040692753 5.476271078 4.209882 2.023048 3.324375 6.244586 6.373501 4.476242 WNT10B 0.608060098 0.055244379 0.041274583 5.476271078 1.874444 2.023048 2.165421 5.705318 3.134528 4.476242 IFIH1 0.593370435 0.057040543 0.043936713 5.476271078 5.335413 2.023048 2.165421 7.109557 6.043524 4.476242 C1orf204 0.565043745 0.061157134 0.049970058 5.476271078 1.874444 2.023048 2.165421 4.802615 3.134528 4.476242 BMP8A 0.638179804 0.052467325 0.03689146 5.475193258 1.874444 2.809601 2.995681 5.448591 4.797798 4.476242 FBP1 0.68308866 0.049394421 0.031341273 5.474495763 2.993831 4.413323 3.764125 7.771052 6.205902 5.446557 ZNF706 0.751989504 0.0466011 0.025488261 5.469676437 7.04469 7.0583 6.769247 9.4454 10.173004 9.220702 LOC282980 0.589875248 0.057439458 0.044641715 5.467479334 1.874444 2.023048 2.995681 4.739845 3.571326 5.446557 PEX13 0.71175857 0.048009392 0.028605648 5.465027325 4.209882 5.487673 4.285996 7.937902 7.53715 6.618407 TAF1 0.721745384 0.047650501 0.027765907 5.455980803 4.743564 4.830496 4.449894 6.811341 7.191402 7.523109 ANKZF1 0.742985759 0.046915454 0.026128615 5.45377576 4.309025 3.872014 3.90836 6.664985 6.319269 6.722123 SCRN1 0.752102871 0.0466011 0.025474651 5.441882825 4.815804 4.80797 2.379345 7.25991 7.174648 6.722123 FUS 0.73358453 0.047307334 0.026829534 5.439262975 7.716122 7.0089 7.422239 9.452312 9.809281 11.35179 ANKRD39 0.691873917 0.048955004 0.030517863 5.439004399 2.201691 2.023048 2.165421 4.718672 4.608763 4.146207 C7orf65 0.68410552 0.049364239 0.031273222 5.439004399 1.874444 2.023048 2.165421 4.013424 4.608763 4.476242 NDUFA2 0.6688089 0.050217419 0.032862879 5.439004399 1.874444 2.406905 2.165421 6.252746 4.608763 3.630092 MPV17L 0.625880611 0.0535411 0.03868867 5.439004399 3.024504 3.32135 2.165421 4.894482 4.608763 6.195186 GLRB 0.587496583 0.057633938 0.045039129 5.439004399 1.874444 2.406905 2.165421 6.395481 4.608763 2.921909 KPNA7 0.566501659 0.060923671 0.049682885 5.439004399 2.201691 2.023048 2.165421 5.743334 4.608763 2.921909 PSMC2 0.638697976 0.05242235 0.036793467 5.434043624 6.186289 6.072636 5.018694 9.212855 8.011679 7.46072 CTR9 0.645131098 0.051833045 0.035882273 5.430404433 5.779429 5.661685 6.056062 7.477873 8.220489 8.84662 DCP2 0.699304832 0.048734593 0.029940116 5.430325412 5.335413 4.911517 5.723602 8.069577 8.011679 7.352555 THAP5 0.669462105 0.050101245 0.032753998 5.425403919 4.815804 4.750708 2.165421 6.063041 6.78473 7.255535 RNF146 0.680974304 0.049464555 0.031554951 5.422892722 5.056948 5.43468 5.596986 7.074163 8.817023 7.873743 ITGA1 0.682092936 0.049418096 0.031463763 5.419948891 4.209882 3.360637 3.935222 6.498222 6.373501 5.882028 TNRC6A 0.703719964 0.048482651 0.029463083 5.418322648 7.177073 6.139057 7.422239 9.146221 9.860086 9.486503 TCERG1 0.747739273 0.046782073 0.025795168 5.41524012 6.45321 6.605686 4.754917 8.65307 9.042712 8.719135 TUFT1 0.664958259 0.050400851 0.033289554 5.411868189 5.263699 5.809601 4.285996 8.964784 7.68534 6.722123 MAT2B 0.652231687 0.051304265 0.034807077 5.410038995 5.335413 4.351315 3.935222 7.771052 7.292524 6.129407 BRCC3 0.62880659 0.053282651 0.038274243 5.410038995 5.335413 3.770995 3.764125 7.771052 7.191402 5.580533 PIGK 0.640254582 0.052240009 0.036544403 5.406328669 4.263463 5.297868 4.508334 6.396698 8.033973 6.942983 NHS 0.700747645 0.048679397 0.029806056 5.404945696 4.743564 4.413323 5.389265 7.177844 7.138979 7.748756 DNASE1L1 0.630351144 0.053156193 0.038031984 5.400202623 3.819732 2.406905 2.379345 6.252746 5.306419 4.476242 NVL 0.65290511 0.051234373 0.034687989 5.397905165 2.993831 2.023048 2.165421 4.894482 4.131418 5.426231 ZNF876P 0.676450865 0.049712169 0.03201293 5.395907064 5.263699 4.736586 4.724406 6.960054 7.191402 7.695565 ZNF436 0.575826438 0.059377251 0.047529092 5.395820187 5.316227 5.43468 6.737132 6.811341 9.168974 8.534542 CENPL 0.635086857 0.052702802 0.037307247 5.392983573 4.743564 4.911517 4.285996 6.283686 7.174648 7.36177 SEL1L3 0.633904612 0.052866846 0.037490303 5.392899178 1.874444 3.32135 3.764125 4.894482 5.317867 6.195186 STK32B 0.689269968 0.04903993 0.030709765 5.3909869 1.874444 2.023048 2.995681 4.013424 5.317867 5.426231 PRMT3 0.637058356 0.05255004 0.037082681 5.3909869 5.744513 3.32135 2.995681 7.748771 7.187136 5.426231 C12orf32 0.620400385 0.053994857 0.039418169 5.3909869 2.201691 3.770995 2.995681 5.743334 4.797798 5.426231 TMED7 0.602522059 0.05597852 0.042294658 5.388189638 6.707871 4.80797 5.571599 9.137671 7.89473 7.291822 PSME2 0.677877156 0.049640889 0.031872746 5.37925091 6.949166 6.821329 6.282905 9.049264 8.71031 9.470756 FLJ45340 0.631700439 0.0530981 0.037847567 5.368742372 8.074081 7.34377 7.69729 9.179923 10.121874 11.011601 PTPMT1 0.667228644 0.050335207 0.033069752 5.366029401 4.743564 4.389936 2.995681 7.167419 6.551443 6.106561 METAP1 0.577527987 0.059116451 0.047217421 5.364191855 5.491121 4.351315 2.379345 7.477873 6.774676 5.446557 SLC39A10 0.574384903 0.059641821 0.047901327 5.364191855 1.874444 4.351315 3.935222 4.739845 6.774676 5.874974 ST7 0.719739421 0.047738047 0.027968016 5.35933045 3.024504 3.32135 3.324375 5.448591 6.613395 5.446557 DCUN1D1 0.674132989 0.049888566 0.03228445 5.359074947 3.819732 3.32135 2.379345 5.743334 7.138979 4.790662 NPDC1 0.669325397 0.050130746 0.032781218 5.354088768 6.554045 6.931478 6.601009 9.02165 8.502167 9.899123 SUMF2 0.744029647 0.046883977 0.026058523 5.349043493 4.309025 6.184248 6.326717 8.745998 8.350533 8.407967 LINC00263 0.656693027 0.050983118 0.034185777 5.347852534 2.993831 2.023048 3.324375 5.743334 4.797798 5.106393 PIK3AP1 0.613960409 0.054598842 0.040336169 5.347852534 1.874444 2.023048 3.324375 5.743334 5.165949 3.676349 TYW5 0.695556872 0.048858998 0.030253147 5.345864671 7.259029 6.35207 6.056062 8.474485 9.366395 9.60665 GRPEL2 0.655177167 0.051064299 0.034364069 5.343965295 5.056948 4.750708 3.90836 7.394225 7.292524 6.32627 PNPLA8 0.617501645 0.054225734 0.039844165 5.337363296 6.973646 5.195784 6.031658 9.33006 8.564762 7.611911 LAX1 0.579823276 0.05881361 0.046775774 5.334979339 8.543486 7.885522 8.83711 9.633502 10.958969 11.301489 ARL2BP 0.769511775 0.046076407 0.024078258 5.323003772 6.054828 6.060401 3.324375 8.105092 8.436733 8.472642 SNAPC5 0.704724796 0.048386088 0.0293508 5.31959759 1.874444 2.406905 2.379345 5.448591 4.131418 4.790662 ACADM 0.647149603 0.05166843 0.035536577 5.30973996 4.743564 4.80797 4.285996 6.244586 7.505595 7.152205 EPC2 0.704294481 0.048419405 0.029402518 5.30931255 4.209882 4.830496 4.449894 8.270632 6.640994 6.618407 HOTAIRM1 0.677913097 0.049626141 0.031854372 5.296849907 6.143785 6.35207 6.861515 8.757204 9.275744 8.519314 CASD1 0.614624799 0.054543342 0.040260633 5.293477868 5.491121 2.406905 3.935222 6.339437 7.406567 5.882028 C5orf60 0.617272994 0.054254364 0.039894522 5.291449402 5.335413 3.770995 3.324375 5.728038 6.640994 7.523109 TMEM5 0.719961409 0.047719802 0.027934672 5.290900462 4.209882 4.389936 3.324375 6.395481 6.613395 6.618407 CACNB4 0.644108311 0.05192151 0.036025859 5.290900462 4.209882 2.809601 4.944468 7.109557 6.613395 5.874974 CTNNA1 0.613093042 0.054675277 0.04046002 5.284902414 6.48761 7.033812 6.919905 10.377176 9.321782 7.988762 CKAP5 0.662870885 0.050504642 0.033484859 5.284569027 4.963444 4.736586 2.379345 7.36523 6.189775 6.722123 PRDM14 0.663653889 0.050460138 0.033403879 5.27239722 7.09018 6.270596 7.156853 8.700282 9.47632 9.555312 TMEM136 0.655981539 0.050993826 0.034247703 5.270787183 4.815804 4.413323 3.90836 6.811341 6.319269 7.020304 TRADD 0.599879064 0.056344664 0.042858796 5.268919693 3.839948 3.770995 2.165421 6.183122 6.237456 4.562324 STAG3L4 0.722229118 0.047646206 0.027712827 5.266714371 2.201691 2.023048 2.165421 5.743334 4.131418 4.562324 ABAT 0.626612171 0.053505098 0.038590677 5.266714371 3.819732 2.406905 2.165421 5.705318 5.353925 4.562324 ANKRD23 0.610791094 0.054914277 0.040777816 5.266714371 1.874444 2.406905 2.165421 5.095353 3.571326 4.562324 ZRSR2 0.599617513 0.05636405 0.042913916 5.266714371 2.201691 2.023048 2.165421 4.718672 3.571326 4.562324 PCGF6 0.595699514 0.056728942 0.043505954 5.266714371 3.024504 3.770995 2.165421 5.095353 6.319269 4.562324 POGZ 0.656715837 0.050983118 0.034178972 5.264351144 6.099991 5.148082 5.723602 8.39062 8.119857 7.553321 LINC00312 0.601268992 0.056215269 0.042613814 5.261285118 4.743564 4.413323 3.935222 5.743334 7.138979 6.924055 CCDC109B 0.624840447 0.053610471 0.038781218 5.257599817 4.639409 5.195784 5.389265 7.814607 7.066159 7.033813 MIR17HG 0.677384083 0.049687867 0.031933311 5.252595862 4.309025 6.044198 6.054038 8.447068 7.819723 7.943848 PHF7 0.602179909 0.056019794 0.042385846 5.250073823 3.350997 2.023048 3.324375 5.743334 5.353925 4.476242 LOC100287314 0.733064369 0.047310912 0.026889418 5.245385786 2.201691 4.389936 3.935222 6.544171 6.237456 6.32627 MYO1B 0.647015547 0.051681274 0.03555359 5.244049302 6.707871 6.537655 6.355801 8.331873 8.928336 9.103055 ECT2L 0.637580165 0.052501106 0.036984689 5.237790537 9.869873 9.382008 9.920257 11.088146 12.258832 13.230974 CDK2 0.652609609 0.051258571 0.034719292 5.230727802 5.263699 6.049721 5.609945 7.30543 8.436733 8.340256 TNFRSF14 0.692856278 0.048944238 0.030421232 5.230659092 5.335413 4.80797 5.217616 7.531061 7.25505 7.722406 EFCAB2 0.719554043 0.047747218 0.027980946 5.229578497 5.335413 4.911517 5.225216 7.656039 7.473335 7.611911 TXNDC9 0.588536782 0.057530341 0.044871725 5.227675967 3.819732 2.023048 2.165421 5.579836 6.205902 3.630092 ANKRD20A9P 0.645122742 0.051833045 0.035895883 5.22049219 9.663383 9.529443 9.976372 11.387609 12.829846 12.047569 SFT2D3 0.618870382 0.054111443 0.039642055 5.219703032 4.309025 3.32135 2.165421 5.705318 5.165949 6.195186 ESRG 0.638326106 0.052467325 0.03686424 5.216873863 6.267718 5.809601 5.225216 7.856887 7.767462 8.650903 PUM2 0.69181226 0.048955004 0.030538278 5.215392864 5.491121 6.42919 6.704285 8.811966 8.842512 8.472642 GM2A 0.659594803 0.050730781 0.033844845 5.213030191 6.099991 5.661685 5.225216 7.607339 8.140553 8.269212 EEF2K 0.59856252 0.056432998 0.043090167 5.211801323 6.617556 6.849665 7.481604 8.346785 9.47632 9.863386 STYX 0.632790307 0.052998119 0.037710786 5.208597546 4.639409 3.360637 4.944468 7.144104 6.043524 7.020304 LOC100190986 0.680212205 0.049490097 0.031597822 5.199359546 6.054828 6.502398 7.156853 8.433162 9.366395 9.430619 LOC282997 0.639291084 0.052350016 0.036676421 5.188531272 4.743564 4.80797 3.90836 6.283686 6.78473 7.428484 PRUNE2 0.727712374 0.047495226 0.027303164 5.182873998 1.874444 2.406905 2.165421 6.283686 4.539173 4.146207 LOC401052 0.712165839 0.047984994 0.028560735 5.182873998 1.874444 2.406905 2.165421 5.728038 4.539173 4.146207 LOC100288069 0.673330451 0.049922388 0.032336849 5.182873998 2.993831 2.023048 2.165421 4.341916 4.539173 6.106561 ZNF2 0.667921893 0.050279153 0.032977203 5.182873998 1.874444 2.406905 2.165421 6.244586 4.539173 3.676349 NLGN4X 0.662823842 0.050504642 0.033498469 5.182873998 2.201691 3.770995 2.165421 5.728038 4.539173 5.580533 FAM105A 0.634519149 0.052771408 0.037399115 5.182873998 3.350997 2.023048 2.165421 8.433162 4.539173 3.630092 LOC338817 0.626378203 0.053505098 0.03860837 5.182873998 2.201691 3.360637 2.165421 5.320955 4.539173 4.790662 AP3B2 0.626166071 0.053522686 0.038660088 5.182873998 2.201691 2.023048 2.165421 5.095353 4.539173 3.630092 C1orf115 0.589210155 0.05748724 0.044760803 5.182873998 3.024504 2.023048 2.165421 6.183122 4.539173 3.630092 C2orf43 0.585674929 0.057930543 0.04547261 5.182873998 2.201691 2.023048 2.165421 6.339437 4.539173 2.921909 CXADRP2 0.572374046 0.060003659 0.048410344 5.182873998 5.328526 3.32135 2.165421 7.656039 4.539173 6.385515 DHFRL1 0.583890327 0.058126643 0.045782919 5.178636586 5.335413 3.872014 5.702912 6.244586 7.713236 7.96648 NR1D2 0.604799916 0.055661385 0.041870024 5.174186189 4.815804 4.830496 5.974145 7.30543 7.187136 7.748756 CDK14 0.690195041 0.048987301 0.030632188 5.169565981 3.819732 2.406905 3.324375 5.579836 6.189775 5.446557 ZBTB41 0.616713666 0.054320822 0.04 5.169565981 3.819732 3.872014 2.995681 7.631894 6.189775 4.562324 GMPPA 0.589390158 0.05748724 0.04474311 5.16895933 6.227577 4.80797 3.324375 7.177844 6.861783 7.553321 C12orf43 0.662863053 0.050504642 0.033491664 5.160975513 6.973646 6.228068 7.030042 8.79031 9.086038 9.397686 GOPC 0.68964546 0.048997321 0.030660769 5.160673696 5.982974 4.911517 5.018694 8.014609 8.350533 7.218312 TMEM161B 0.654088719 0.051134477 0.034515141 5.160105894 4.743564 3.360637 3.764125 5.728038 6.608026 6.942983 ARL4A 0.653210101 0.051218943 0.034638312 5.160105894 4.309025 3.360637 3.935222 5.728038 6.549959 6.385515 SDHAF2 0.603041842 0.055919113 0.042194624 5.158947283 6.924263 5.789702 5.225216 8.156778 7.68534 9.123341 CEBPZ 0.755776339 0.046493188 0.025157537 5.157810389 5.856559 6.03611 2.165421 7.937902 8.402869 7.920856 PDE6D 0.632935334 0.052996828 0.037699898 5.157519487 3.819732 4.80797 2.165421 5.448591 7.174648 6.051818 PLEKHG3 0.60477696 0.055661385 0.041876829 5.157519487 4.815804 4.80797 4.754917 6.339437 7.174648 7.255535 COG6 0.649330656 0.051527347 0.035140524 5.155073589 4.743564 2.809601 2.379345 7.109557 6.78473 4.476242 ITM2B 0.660601263 0.05067924 0.033741409 5.151145124 9.782496 9.342669 9.765631 12.130524 12.487096 11.379464 ACAA1 0.723436509 0.047612321 0.02760803 5.135957766 2.201691 2.023048 2.379345 6.550689 4.131418 4.562324 KIAA1524 0.610679563 0.054959374 0.040826812 5.135485008 1.874444 3.360637 2.379345 4.739845 4.539173 5.106393 PRKCQ 0.682628202 0.049399307 0.031403879 5.134037834 2.993831 3.32135 2.379345 5.026959 5.353925 5.580533 ATHL1 0.568815705 0.060479768 0.049167744 5.125966006 6.846868 6.904719 6.737132 9.204692 7.89473 9.910841 TRPC6 0.618099005 0.054162167 0.039720313 5.120725443 4.263463 2.809601 3.324375 6.067497 5.165949 6.129407 FLOT1 0.647565337 0.051665552 0.035471929 5.120291279 7.671922 7.152299 6.919905 9.08528 9.508524 10.176565 MGC21881 0.642153618 0.052008291 0.036247703 5.119491911 5.658609 2.809601 4.449894 8.014609 6.608026 6.385515 NR2C2 0.573183225 0.059824474 0.048218442 5.116783437 3.839948 4.389936 5.571599 6.811341 7.414086 6.195186 PRKRA 0.585472402 0.05794619 0.045503232 5.108348839 6.381847 4.736586 5.723602 8.734704 8.098861 6.931222 LOC100289341 0.630820136 0.053142215 0.037921062 5.107876878 6.820119 6.092406 6.737132 8.190235 9.148683 9.172843 C1orf220 0.616408846 0.054342412 0.040024498 5.098608444 4.682076 4.736586 5.723602 7.33564 7.406567 7.03218 EDA2R 0.585405813 0.05795448 0.045537258 5.098003049 4.263463 2.023048 3.324375 4.718672 6.613395 5.446557 SH3TC2 0.568261888 0.060624168 0.049333106 5.097631347 3.839948 3.32135 2.165421 4.013424 6.189775 6.106561 ARHGEF3 0.612470045 0.054769559 0.040547125 5.094076361 4.309025 2.809601 4.508334 6.857154 6.319269 5.580533 LOC100128640 0.613642586 0.054623981 0.040370194 5.083406092 6.707871 5.148082 7.003286 7.897963 9.053666 9.143346 METAP2  0.718963592 0.047781016 0.02804083 5.079134345 6.143785 4.413323 6.636262 8.801178 8.350533 8.488368 POLR1B  0.647223324 0.05166843 0.035516162 5.079066186 4.263463 4.911517 3.90836 6.396698 6.608026 7.020304 TECPR1  0.685778284 0.049293152 0.031079959 5.078303514 8.379096 7.843866 8.234655 10.178935 10.687282 10.723442 LOC100506548  0.580372581 0.058778844 0.046680504 5.075488405 6.554045 5.297868 7.003286 7.33564 9.237827 9.346832 CCDC14  0.598344109 0.056462942 0.043150051 5.071701192 5.658609 5.297868 6.601009 8.087444 8.436733 7.640338 C11orf73  0.704276825 0.048419405 0.029409323 5.071583124 4.209882 4.389936 3.764125 6.544171 7.473335 6.106561 RAB2A  0.651060775 0.05143697 0.034948622 5.062420553 6.997718 6.072636 5.596986 9.337546 9.107223 7.774634 PRLR  0.59133023 0.057248319 0.044357264 5.061860622 4.743564 4.911517 4.754917 8.514658 7.094585 5.882028 NDRG4  0.599381794 0.056379839 0.042952705 5.060666722 1.874444 2.023048 2.379345 4.718672 3.571326 4.476242 TMEM123  0.611495917 0.054837105 0.0406492 5.055485034 5.897292 6.466258 6.670675 10.548217 8.804107 7.352555 CDK5RAP2  0.611850253 0.05481369 0.040600885 5.049800489 6.008206 4.413323 3.90836 6.244586 8.119857 7.428484 SMAP2  0.617233549 0.054273567 0.03993263 5.048114459 6.846868 5.487673 7.4423 9.778045 8.486085 8.784285 LYST  0.627679976 0.053394669 0.038430759 5.041528418 4.743564 3.770995 5.018694 6.063041 7.25505 7.352555 C7orf29  0.573089776 0.059837281 0.048240898 5.038311881 3.819732 2.406905 2.165421 4.739845 4.131418 6.649696 SPARC  0.686249296 0.049293152 0.031021436 5.037439699 9.186094 8.692451 9.179489 11.29645 12.17227 11.025142 PDE7A  0.679031174 0.049543679 0.031723035 5.037116882 6.306772 4.911517 7.056312 8.915622 8.63937 8.593895 ICA1  0.590561774 0.057341112 0.044492685 5.034921624 4.309025 6.42919 5.217616 8.206677 6.640994 8.269212 ZNF37A  0.592244706 0.057117807 0.044147669 5.034621192 6.58615 6.072636 5.609945 7.274575 8.904331 8.918033 VEGFB  0.634785997 0.052753682 0.037376659 5.027323625 6.617556 5.148082 5.389265 7.477873 8.296229 8.60836 MTRF1  0.594147666 0.056928919 0.043758421 5.026034632 3.024504 2.023048 2.379345 5.252045 5.353925 3.676349 RP1-177G6.2  0.589042755 0.05748724 0.044781218 5.02313918 6.617556 5.789702 6.601009 7.607339 9.158864 8.929599 ZMYND19  0.609929413 0.055085743 0.040964274 5.018039775 2.993831 2.023048 2.165421 5.320955 5.306419 3.630092 IFT140  0.579874462 0.05881361 0.046768969 5.011608367 1.874444 2.023048 2.995681 5.320955 4.608763 3.630092 SREK1  0.685096409 0.04931773 0.031165703 5.009343851 7.530567 7.152299 7.056312 9.794456 9.586024 9.380933 NACAD  0.611783253 0.05481369 0.040614495 5.006890649 4.263463 2.023048 3.764125 5.320955 5.509998 6.587378 C14orf102  0.584855955 0.058042825 0.045643416 5.004323696 4.815804 3.360637 3.324375 5.026959 7.138979 6.385515 ZNF263  0.603579672 0.055777445 0.042061245 5.004312023 4.815804 3.872014 4.754917 6.664985 7.187136 6.195186 LSM5  0.615811811 0.054407447 0.040106839 5.003678354 7.09018 6.092406 6.369239 8.604261 8.777924 8.692228 PHF6  0.653217871 0.051218943 0.034631507 5.000891462 2.993831 2.023048 2.995681 5.252045 5.317867 4.562324 GCC1  0.609322441 0.055142692 0.04106771 5.000891462 3.024504 2.023048 2.995681 5.448591 5.317867 4.146207 ADAM19  0.595721078 0.056728942 0.043499149 5.000352438 1.874444 3.872014 4.285996 4.894482 6.608026 5.900694 RRM1  0.606741943 0.055431478 0.041521606 4.997075608 3.350997 4.413323 5.596986 7.918071 7.414086 5.634184 CABP1  0.70841444 0.04824159 0.02893229 4.98940818 1.874444 2.023048 2.165421 4.341916 4.131418 5.106393 CYP4B1  0.647991241 0.051631895 0.035384825 4.98940818 1.874444 2.023048 2.165421 4.341916 5.353925 3.630092 CARD11  0.643521736 0.051940717 0.036104798 4.98940818 1.874444 2.023048 2.165421 4.341916 3.571326 5.446557 PLAC8  0.640739001 0.052197898 0.036480436 4.98940818 1.874444 2.023048 2.165421 4.341916 5.165949 3.630092 MTRNR2L10  0.62951332 0.053240793 0.038159918 4.98940818 1.874444 2.023048 2.165421 4.341916 3.571326 5.091834 MED6  0.620173776 0.054006231 0.039462402 4.970029894 5.982974 5.195784 6.737132 8.579223 8.296229 7.943848 HSD3BP4  0.696278507 0.048851278 0.030197346 4.964909299 3.350997 2.406905 3.324375 4.718672 5.509998 7.352555 PYCR2  0.599691149 0.056357089 0.042890779 4.961652994 3.819732 2.809601 2.165421 5.728038 5.509998 4.476242 HRH2  0.598561441 0.056432998 0.043100374 4.961652994 1.874444 2.023048 2.165421 4.341916 3.571326 4.476242 KBTBD12  0.598561441 0.056432998 0.043100374 4.961652994 1.874444 2.023048 2.165421 4.341916 3.571326 4.476242 EFCAB11  0.589077635 0.05748724 0.044774413 4.961652994 1.874444 2.809601 2.165421 5.705318 3.571326 4.476242 PDCD4  0.687746537 0.049134487 0.030823409 4.956839287 7.021395 5.340619 7.680498 9.633502 9.330816 9.201749 LMO4  0.651048417 0.05143697 0.034955427 4.955527682 7.410173 5.43468 7.956385 9.54575 10.265423 8.96375 DMD  0.685399662 0.049314432 0.031134399 4.941064812 5.056948 5.487673 4.285996 7.70315 7.191402 7.36177 POLR2G  0.631878658 0.05307838 0.037825111 4.93875207 6.898923 6.03611 5.225216 8.553743 8.314558 8.340256 MRVI1  0.59217015 0.057129881 0.044166043 4.936965583 5.897292 4.736586 6.737132 7.274575 8.200916 8.986077 PHLDB2  0.633722901 0.052882301 0.037519564 4.932209488 4.309025 4.830496 3.935222 6.396698 6.237456 7.46072 FIS1  0.699549026 0.048733855 0.029908813 4.925617809 7.463005 7.421341 7.082111 9.698891 9.76331 9.562759 CASP2  0.637503754 0.052501106 0.036998299 4.919662898 5.982974 4.80797 5.571599 7.877571 7.870158 7.492252 LYPLA2  0.622935626 0.053781042 0.039028241 4.919053136 4.209882 4.351315 5.217616 7.792994 6.373501 6.649696 LOC100128164  0.7221269 0.047646206 0.027726438 4.916195348 1.874444 3.770995 3.90836 5.743334 6.205902 6.051818 TP53I3  0.667530282 0.050323626 0.033050698 4.916195348 1.874444 4.80797 3.90836 6.498222 6.205902 6.106561 MYCBP2  0.70479151 0.048386088 0.029330384 4.91463052 5.700376 6.060401 6.072169 7.918071 9.25691 8.357484 CMPK2  0.601508874 0.056113873 0.042528071 4.912654932 3.839948 3.770995 3.324375 6.067497 4.608763 7.748756 PPP2R5C  0.626342797 0.053505098 0.038615175 4.912630893 5.753024 5.809601 6.054038 7.582358 8.350533 8.232333 LOC338651  0.601083764 0.056247441 0.042656005 4.912476789 3.024504 3.872014 4.944468 5.320955 6.774676 6.931222 CFL2  0.641416334 0.052107192 0.036366111 4.910595455 5.779429 5.43468 4.724406 8.433162 7.68534 7.020304 SEPT7P2  0.706100317 0.048351237 0.029220823 4.90948268 6.186289 2.023048 6.369239 7.937902 7.870158 8.66481 LCP2  0.723793799 0.047585406 0.027584893 4.905210095 4.743564 2.406905 4.449894 7.037879 6.613395 6.587378 C15orf23  0.598356033 0.056462942 0.043143246 4.901971869 3.024504 2.023048 2.165421 5.095353 5.317867 3.676349 DIP2B  0.657504014 0.050903629 0.034116366 4.879821557 3.819732 4.736586 2.165421 5.891233 6.640994 6.106561 LIN54  0.593764493 0.057012338 0.043849609 4.87981284 4.263463 3.32135 3.90836 5.095353 7.094585 6.195186 YY1  0.583364397 0.058208993 0.045893841 4.874324244 5.744513 6.670655 7.273415 9.558617 9.158864 7.825039 DPYSL2  0.59248399 0.057110241 0.044096632 4.870248403 7.918838 6.03611 7.204614 8.139755 10.202833 10.096736 CTSL1P2  0.582786783 0.058317693 0.046062606 4.867468606 6.381847 7.679931 7.156853 8.665019 9.009341 10.265959 EHMT1  0.582734302 0.058324851 0.046082341 4.864571601 6.417969 5.195784 3.935222 8.700282 7.473335 6.649696 PLA2G4A  0.625586482 0.053562842 0.038721334 4.86323049 3.024504 2.023048 2.995681 5.095353 5.306419 4.476242 NRD1  0.647739242 0.051631895 0.035429738 4.855441047 4.963444 3.770995 5.217616 7.243046 6.608026 7.352555 PRKD1  0.706536691 0.048309794 0.029147329 4.854756561 1.874444 3.32135 3.764125 5.448591 6.043524 5.580533 EPT1  0.648958272 0.051556323 0.035207894 4.84851789 6.45321 6.877454 6.326717 8.604261 8.842512 8.858771 PPP3CA  0.599918036 0.056344664 0.04285199 4.838756121 6.099991 6.466258 5.217616 8.190235 8.904331 7.492252 P2RY14  0.628903623 0.053255542 0.038246342 4.838470141 2.201691 2.406905 2.165421 6.396698 3.571326 4.476242 TUBGCP4  0.592296984 0.057117807 0.044134059 4.838470141 2.201691 3.360637 2.165421 6.183122 4.131418 4.476242 ZFX  0.582020154 0.058454033 0.046244301 4.836098269 5.779429 4.750708 4.944468 7.177844 7.269549 7.218312 DNAJB6  0.646183047 0.051798486 0.035724396 4.835844007 8.877752 9.104741 9.696318 11.534875 11.874698 11.151519 TMEM175  0.632058571 0.05307838 0.037818306 4.835487348 2.993831 5.362142 6.012527 8.286188 7.191402 6.924055 ATF7IP  0.688548406 0.049115877 0.030782579 4.830624127 4.743564 4.750708 5.723602 7.995811 7.942653 6.931222 C9orf68  0.601231615 0.056227768 0.042632188 4.829132256 1.874444 2.023048 2.995681 4.739845 4.539173 4.146207 EZR  0.669200368 0.050158501 0.032815243 4.816536816 7.278811 7.926009 7.762571 11.328733 10.030567 9.329475 MIS18BP1  0.591874444 0.057215069 0.044250425 4.812457552 5.897292 3.872014 5.389265 7.656039 7.713236 6.73963 CHCHD1  0.568846404 0.060479768 0.049154134 4.810968868 6.143785 4.911517 3.935222 7.177844 7.505595 6.942983 YAF2  0.606188496 0.055489397 0.041642055 4.809587016 7.943836 7.033812 5.974145 9.299725 9.426624 9.143346 AP1S3  0.626727115 0.053474985 0.038547805 4.807833173 4.639409 4.351315 4.754917 6.954147 6.319269 7.020304 DHX36  0.706360824 0.048309794 0.029160939 4.793999137 6.873131 6.572071 5.217616 8.833301 9.086038 8.692228 BBS2  0.592897292 0.057080847 0.04401293 4.793512098 6.417969 5.487673 4.724406 7.170315 7.793829 7.748756 FLJ35390  0.682433052 0.04941326 0.031444029 4.789116491 4.263463 4.389936 3.935222 6.498222 6.373501 6.649696 L3MBTL3  0.608009189 0.055250119 0.041296359 4.787203117 2.993831 3.32135 3.764125 4.894482 6.373501 5.580533 EXOC4  0.588633498 0.057508969 0.044825451 4.787203117 4.309025 3.32135 2.379345 5.252045 5.920411 5.580533 COL2A1  0.585421787 0.05795448 0.045530453 4.783987856 2.993831 2.023048 2.379345 5.252045 5.165949 3.676349 PARP2  0.610222281 0.055039622 0.040912555 4.783859583 5.304463 3.872014 4.285996 6.544171 7.292524 6.455366 ASPM  0.691608132 0.048955004 0.030551888 4.779881377 1.874444 2.023048 2.165421 5.320955 4.131418 4.146207 FAM169A  0.691518888 0.048955004 0.030558693 4.779881377 1.874444 2.023048 2.379345 6.067497 4.131418 4.146207 TRIM69  0.679536444 0.049531477 0.031673358 4.779881377 1.874444 2.023048 2.995681 5.252045 4.131418 5.106393 RPUSD2  0.672656516 0.049933984 0.032413066 4.779881377 1.874444 2.023048 2.165421 4.739845 4.131418 4.146207 CD27  0.650183578 0.05147219 0.035021436 4.779881377 1.874444 2.023048 3.324375 5.026959 4.131418 5.580533 AKR1E2  0.626336431 0.053505098 0.03862198 4.779881377 1.874444 3.32135 2.165421 5.252045 4.131418 5.106393 NUF2  0.606579002 0.055458006 0.041565839 4.779881377 1.874444 3.360637 2.379345 6.183122 4.131418 4.562324 GPRC5B  0.604211424 0.055732254 0.042002722 4.779881377 1.874444 2.023048 3.324375 6.396698 4.131418 4.146207 GEMIN8P4  0.593461676 0.057025989 0.043900646 4.779881377 1.874444 2.406905 2.995681 4.802615 4.131418 4.790662 SDC3  0.610281783 0.055039622 0.04090575 4.777856422 4.309025 3.770995 2.995681 5.252045 8.181074 5.426231 GANC  0.599150193 0.056396398 0.043001021 4.777856422 3.350997 2.023048 2.995681 5.252045 5.306419 4.476242 TMEM167A  0.652254763 0.051304265 0.034793467 4.757034401 6.554045 5.809601 5.596986 8.527804 8.804107 7.774634 FAM13A  0.668516292 0.050253093 0.032900987 4.754714923 5.982974 6.35207 6.489771 8.501391 9.2474 8.232333 NCEH1  0.630411636 0.053156193 0.038011569 4.749912062 2.993831 2.809601 3.935222 6.183122 4.797798 5.900694 WARS2  0.628430812 0.053328876 0.038332766 4.749912062 4.815804 3.360637 3.935222 6.183122 6.774676 6.129407 UBC  0.667125321 0.050335207 0.033090167 4.749465528 3.819732 4.750708 2.165421 6.067497 6.640994 6.051818 LACTB  0.634483165 0.052771408 0.03740592 4.749465528 3.819732 2.809601 3.324375 6.067497 5.317867 5.426231 HNRNPU-AS1  0.583168111 0.058250261 0.045963253 4.748361894 5.304463 5.148082 7.132367 8.822673 8.350533 7.395512 CAMK1D  0.58093219 0.058719081 0.046565498 4.748162376 4.963444 6.537655 6.072169 7.210813 8.486085 8.636861 EIF2S3  0.66830737 0.050279153 0.032939095 4.740249064 7.021395 7.033812 6.369239 10.21189 9.266358 8.503924 CCDC104  0.645129397 0.051833045 0.035889078 4.738801666 5.744513 4.351315 5.018694 7.167419 7.989035 7.152205 TJP1  0.629425389 0.053243865 0.038172167 4.73375864 5.982974 6.184248 5.592916 7.835902 8.564762 7.988762 ADARB2  0.597089754 0.056614769 0.043346717 4.731893934 4.309025 4.413323 2.995681 4.894482 6.551443 7.748756 IL13RA1  0.591686543 0.057222443 0.044291936 4.730182156 5.263699 6.092406 4.944468 7.243046 7.505595 8.010706 EFHC1  0.675107981 0.049822189 0.032169445 4.727950373 6.617556 6.049721 7.030042 8.854326 9.128102 8.858771 NEK7  0.59747759 0.056551179 0.043271181 4.713640765 6.143785 6.044198 6.527811 8.616619 8.764653 7.748756 HBXIP  0.676883207 0.049712169 0.031985709 4.70866159 7.445608 7.615377 7.360327 10.236122 9.680925 9.525135 CYBA  0.626875294 0.053474985 0.03852739 4.702329925 5.897292 6.03611 4.944468 7.177844 8.011679 8.894619 DDX41  0.647822651 0.051631895 0.03540524 4.698660797 5.779429 5.809601 5.018694 7.109557 8.011679 8.870819 VPS26A  0.696918857 0.04882091 0.030147669 4.69812704 3.819732 3.32135 3.90836 7.607339 5.509998 6.051818 PSAP  0.635309129 0.052679972 0.037282749 4.69315026 9.316235 8.445606 9.048192 11.223584 11.897679 10.676162 GNPDA2  0.638895026 0.052413388 0.036753998 4.689449412 2.993831 2.023048 2.379345 5.026959 4.608763 4.562324 PAPOLG  0.681468807 0.049458162 0.031519564 4.68852063 5.335413 6.139057 6.355801 8.376156 8.36819 8.32282 TMEM87B  0.585445053 0.057952709 0.045517523 4.686369198 5.304463 4.389936 2.165421 6.664985 5.936219 6.618407 LTBR  0.581543854 0.058540518 0.046342974 4.684705832 4.963444 4.413323 3.935222 6.183122 7.191402 6.32627 B3GNT7  0.588477237 0.057530341 0.04487853 4.683348549 3.024504 4.413323 3.324375 5.252045 6.237456 5.874974 LOC339788  0.635330128 0.052679972 0.037275944 4.681160123 5.491121 5.195784 4.724406 7.42265 7.107836 7.523109 DSTYK  0.630597135 0.053156193 0.037977543 4.660749298 7.730559 6.572071 6.769247 8.591796 9.673843 9.951121 UHMK1  0.570037332 0.06033194 0.048909833 4.658599905 5.335413 3.360637 3.935222 7.274575 6.608026 5.580533 RMI1  0.675810438 0.049763477 0.032100034 4.652769951 4.682076 4.389936 3.90836 6.811341 6.608026 6.587378 LOC100507501  0.667943435 0.050279153 0.032970398 4.651279958 5.056948 5.340619 5.544653 7.274575 7.505595 8.340256 PJA2  0.606837943 0.05543128 0.041510718 4.641433488 7.317579 6.060401 6.056062 8.270632 9.468155 8.579284 ORC6  0.574084374 0.059729834 0.04804083 4.632632095 7.744853 6.42919 7.082111 8.641022 9.492512 9.50208 YPEL3  0.674347123 0.049848381 0.032241579 4.620798576 6.417969 4.736586 6.031658 8.087444 8.2398 8.440667 MARCH6  0.64352197 0.051940717 0.036097993 4.6202491 7.04469 6.983552 7.003286 9.919426 8.777924 9.211256 RAPGEF2  0.589760204 0.057461905 0.044668255 4.619472198 5.744513 6.139057 5.571599 8.346785 8.055928 7.36177 ING3  0.618159422 0.054162167 0.039713508 4.618368323 5.335413 4.830496 3.90836 7.037879 7.107836 6.722123 EIF4G2  0.70334423 0.048494719 0.029531814 4.612257841 8.151234 8.101237 8.151795 11.235653 10.356707 10.275054 LOC338739  0.581441763 0.058561473 0.046375638 4.607878853 3.839948 4.389936 5.544653 6.283686 6.551443 7.748756 MRPL46  0.622243042 0.053817472 0.039177952 4.606193653 3.839948 2.023048 2.165421 4.013424 6.043524 5.580533 CDK13  0.626764006 0.053474985 0.038541 4.604582504 6.186289 5.340619 5.596986 7.42265 8.963611 7.800057 SMG1  0.572186896 0.060021442 0.048436883 4.603561826 6.099991 6.311907 7.481604 8.514658 9.275744 8.503924 LOC400084  0.631452828 0.053106978 0.037870704 4.600716125 3.024504 2.406905 2.165421 4.013424 4.608763 6.722123 ST8SIA4  0.580597455 0.058752276 0.046631507 4.600716125 3.024504 2.406905 3.90836 7.210813 4.608763 4.790662 PCM1  0.654778509 0.051064299 0.034420551 4.588190724 6.52121 6.849665 6.800663 9.23707 8.916384 8.719135 LGMN  0.604129724 0.055732254 0.042009527 4.571223597 6.846868 5.809601 6.489771 7.937902 8.682351 9.267025 MLL5  0.565601392 0.061091369 0.049854372 4.569436364 7.278811 6.311907 7.156853 9.704692 8.817023 8.503924 RPL14  0.646855426 0.051704967 0.035586254 4.567449791 10.288639 10.341668 10.357997 12.533057 12.852763 12.223493 SREK1IP1  0.618667464 0.054133185 0.039673358 4.563890635 7.067614 6.311907 5.225216 8.447068 8.077554 9.257878 SCIN  0.594343739 0.056918505 0.043734604 4.558779321 1.874444 3.32135 3.935222 4.739845 5.509998 5.882028 RGS10  0.590742688 0.057311568 0.044433481 4.555775177 5.335413 6.270596 6.072169 9.12907 7.767462 7.523109 RNF20  0.58989068 0.057439458 0.04463491 4.540902856 4.309025 2.809601 2.379345 6.067497 5.920411 4.562324 UBR7  0.605281751 0.055617731 0.041808778 4.53061323 4.682076 3.770995 3.935222 6.244586 6.861783 5.874974 LOC401320  0.655895222 0.050993826 0.034274923 4.528824992 4.209882 5.148082 5.571599 7.144104 7.656894 7.327219 ATXN3  0.598892344 0.056423848 0.043039809 4.521019299 7.513971 7.129367 7.030042 8.935488 9.321782 9.690619 ANKRD26P1  0.654941727 0.051064299 0.034400136 4.520541748 1.874444 2.023048 2.165421 4.341916 4.131418 4.146207 APITD1  0.611103378 0.054867364 0.040699558 4.520541748 1.874444 2.406905 2.165421 4.341916 5.353925 3.630092 SLC9A4  0.600589129 0.056308034 0.042746512 4.520541748 2.201691 2.023048 2.165421 4.341916 3.571326 5.091834 NRAS  0.663336995 0.05046582 0.033423613 4.520430032 6.898923 6.311907 4.508334 8.801178 8.314558 8.488368 PPFIBP2  0.642438185 0.051967533 0.036194624 4.512901426 4.263463 4.413323 2.165421 5.891233 6.043524 6.587378 HMBS  0.566532954 0.060923671 0.04967608 4.506846946 2.993831 2.023048 2.165421 4.739845 5.165949 3.676349 LONP2  0.605566255 0.055588631 0.041769309 4.505359624 7.177073 7.08238 7.92821 9.204692 9.348715 10.284093 NCALD  0.60898809 0.055156748 0.04114801 4.504413157 2.993831 4.830496 3.935222 6.664985 5.936219 6.106561 KIAA1715  0.62850987 0.053328876 0.038325961 4.499553673 5.700376 5.43468 4.285996 7.36523 7.870158 7.180104 NECAP1  0.609380834 0.055133391 0.041052059 4.497544857 4.963444 6.03611 4.754917 8.087444 7.598264 6.924055 RBBP4  0.66840825 0.050269006 0.03291936 4.496666752 7.373845 7.240547 7.317525 9.486381 9.809281 9.380933 NCOA4  0.575569102 0.059462702 0.047625723 4.495829863 7.317579 7.323707 6.527811 9.744652 8.696398 9.008063 PAN3  0.587154536 0.057666624 0.045105818 4.486167914 6.898923 6.702075 6.369239 9.220972 8.867558 8.175185 TRIM41  0.629716505 0.053228219 0.038127254 4.480008275 3.350997 4.413323 4.449894 6.396698 6.613395 6.051818 HERPUD2  0.619939035 0.054008689 0.039480095 4.477992615 6.267718 5.297868 5.544653 8.239009 8.119857 7.46072 DYNC1LI1  0.610915674 0.054914277 0.040760122 4.469656416 5.658609 6.049721 6.072169 7.976765 7.819723 8.232333 ARMC9  0.619494096 0.054008689 0.039522286 4.468616614 2.993831 2.406905 2.379345 5.252045 4.539173 4.562324 ZNF778  0.593045604 0.057053082 0.043980265 4.468616614 1.874444 2.406905 2.379345 5.026959 4.539173 3.630092 JMJD7  0.580564256 0.058752276 0.046638312 4.468616614 1.874444 2.406905 2.379345 6.811341 4.539173 2.921909 QTRTD1  0.606242536 0.055476612 0.041623682 4.466478121 1.874444 4.750708 3.90836 6.067497 6.549959 5.446557 GTF3C2  0.592542252 0.057105447 0.044074855 4.464492619 4.963444 6.092406 5.544653 7.70315 7.740604 7.492252 NMD3  0.645279256 0.051831344 0.035853692 4.460197426 5.316227 5.195784 5.723602 8.65307 7.473335 7.255535 APOA1BP  0.599828664 0.056344664 0.042865601 4.457570112 5.304463 4.413323 4.449894 6.244586 7.107836 7.46072 PCSK5  0.632511246 0.053040507 0.037764546 4.451200429 5.897292 6.092406 6.326717 8.051486 8.502167 8.232333 EMX2OS  0.59865878 0.056432998 0.043076557 4.45018608 5.056948 6.060401 4.754917 7.210813 7.191402 8.194487 INTS3  0.583594776 0.058194436 0.045845526 4.447364981 5.744513 5.789702 6.072169 7.477873 7.942653 8.287303 RAD23B  0.62012434 0.054006231 0.039469207 4.446652462 7.6108 7.87177 7.462086 10.149468 9.468155 9.76352 CHORDC1  0.577611187 0.059114532 0.047206533 4.442949661 5.700376 6.605686 6.861515 8.757204 9.540026 7.611911 ARPC5L  0.588623185 0.057508969 0.044832256 4.435879596 5.700376 4.736586 6.056062 8.190235 7.066159 7.849596 DCUN1D4  0.599133078 0.05640611 0.043017353 4.420622621 4.815804 4.911517 6.012527 6.960054 7.767462 7.640338 DNAJC13  0.584295739 0.058106817 0.045730521 4.418475241 5.897292 4.736586 4.508334 6.651882 7.767462 7.327219 UHRF1BP1  0.577854374 0.059077666 0.047167744 4.418475241 5.491121 4.389936 4.508334 6.651882 6.640994 7.46072 PHF16  0.649901625 0.051478217 0.035047295 4.412037769 3.024504 3.32135 2.379345 5.320955 5.165949 5.091834 SGPP1  0.58250627 0.058351052 0.046125893 4.412037769 3.024504 2.023048 2.995681 4.718672 5.165949 4.476242 ZNF346  0.631557526 0.053106978 0.037863899 4.409870064 7.671922 8.016282 8.102218 9.693068 10.626217 10.157018 PAK3  0.665397621 0.050389557 0.033233072 4.408310355 2.201691 2.023048 2.379345 4.341916 5.306419 4.146207 FBXL4  0.630640513 0.053156193 0.037955767 4.408310355 2.201691 2.023048 2.995681 4.341916 6.205902 4.146207 LOC441204  0.676775503 0.049712169 0.032006125 4.404505427 1.874444 2.023048 2.165421 4.013424 5.317867 4.146207 FGF7  0.667814352 0.050279153 0.032997618 4.404505427 1.874444 2.023048 2.165421 4.013424 4.131418 5.091834 CLEC4C  0.659342336 0.050730781 0.03386526 4.404505427 1.874444 2.023048 2.165421 4.013424 4.797798 4.146207 KIF6  0.649081697 0.05155431 0.035197006 4.404505427 1.874444 2.023048 2.165421 4.013424 4.539173 4.146207 TFDP2  0.602911049 0.055929015 0.042215039 4.402755746 6.792865 6.670655 7.401896 8.553743 9.28507 9.540302 KIAA0090  0.613344067 0.054649646 0.040415107 4.397153419 4.209882 3.360637 3.764125 5.891233 5.936219 5.900694 SGOL2  0.608078561 0.055241507 0.04125689 4.397153419 4.209882 2.023048 3.764125 5.320955 5.936219 5.900694 RPS6KA3  0.665245947 0.050393971 0.033264376 4.395032475 5.897292 5.148082 6.012527 8.033165 8.098861 7.920856 RNF207  0.590999749 0.057296054 0.044412385 4.392869701 3.819732 4.413323 3.90836 6.954147 6.043524 5.634184 RPL30  0.627841934 0.053359515 0.038388568 4.38930984 12.434528 12.527359 12.674306 14.402267 14.661354 15.012718 NEB  0.600909688 0.05625806 0.042681865 4.384061903 3.819732 2.406905 3.324375 6.814118 4.539173 5.426231 LOC648740  0.598432765 0.056461394 0.043130997 4.384061903 2.993831 2.406905 2.995681 6.063041 4.539173 4.562324 MANSC1  0.620990997 0.053929257 0.03933787 4.375833998 5.328526 4.830496 4.449894 6.960054 6.551443 8.095288 LARP7  0.621388224 0.053905072 0.039289554 4.374608916 5.897292 5.43468 5.596986 7.726141 7.819723 7.668215 ARNTL2  0.665305814 0.050389557 0.033246683 4.363982547 5.744513 6.139057 3.324375 7.531061 7.870158 8.03232 CYB561D2  0.582833203 0.058317693 0.046055801 4.362655941 3.839948 3.32135 2.379345 4.802615 5.857745 5.446557 RFC1  0.586053788 0.057869242 0.04536509 4.361371767 4.815804 5.297868 3.764125 7.42265 6.373501 6.722123 MAP3K12  0.577304935 0.05913221 0.047248724 4.357685141 4.682076 2.023048 5.544653 5.705318 6.551443 7.668215 NTM  0.633597422 0.052918525 0.037575366 4.35647027 1.874444 2.023048 2.165421 5.705318 3.571326 4.146207 1/2-SBSRNA4  0.617330403 0.054248673 0.03987819 4.35647027 1.874444 2.023048 2.165421 5.252045 3.571326 4.146207 FAAH2  0.611203161 0.054867364 0.040681865 4.35647027 1.874444 2.023048 2.165421 5.095353 3.571326 4.146207 LRRC6  0.602850516 0.055929015 0.042221844 4.35647027 1.874444 2.023048 2.165421 4.894482 3.571326 4.146207 SEMA4G  0.602846132 0.055929015 0.042228649 4.35647027 1.874444 2.023048 2.165421 6.339437 3.134528 4.146207 MED20  0.600837653 0.056271437 0.042700919 4.35647027 4.309025 2.023048 2.165421 5.705318 6.205902 4.146207 TIGD3  0.575196242 0.059557774 0.047758421 4.35647027 1.874444 2.023048 2.165421 4.341916 3.571326 4.146207 NHLRC1  0.59406393 0.056941984 0.043777475 4.333154296 4.815804 5.148082 5.225216 6.960054 7.406567 6.931222 ADAMTS9-AS2  0.570575458 0.060307793 0.048817965 4.324586544 2.993831 2.023048 3.764125 5.579836 4.608763 5.106393 FABP5  0.56713409 0.060808506 0.049514801 4.323801552 5.700376 6.049721 5.723602 7.835902 7.25505 8.534542 ILDR2  0.575983323 0.059372673 0.047506635 4.319043905 1.874444 4.351315 2.995681 6.395481 4.797798 5.106393 C1orf64  0.692028347 0.048955004 0.03050017 4.312039929 1.874444 2.023048 2.165421 7.607339 4.131418 3.630092 LINC00277  0.660698794 0.050657328 0.033710786 4.312039929 1.874444 2.023048 2.165421 6.396698 4.131418 3.630092 DNAH7  0.650932948 0.051450055 0.034987411 4.312039929 1.874444 2.023048 2.165421 6.067497 4.131418 3.630092 KIF11  0.650932948 0.051450055 0.034987411 4.312039929 1.874444 2.023048 2.165421 6.067497 4.131418 3.630092 MKI67  0.640654816 0.052197898 0.036487241 4.312039929 1.874444 2.023048 2.165421 5.743334 4.131418 3.630092 LOC375196  0.623702521 0.053740303 0.038926165 4.312039929 1.874444 2.023048 2.165421 5.095353 4.131418 3.676349 TDRD5  0.60427789 0.055729438 0.041980946 4.312039929 1.874444 2.023048 2.165421 7.144104 4.131418 2.921909 JPH4  0.588345849 0.057537859 0.044900306 4.312039929 3.024504 2.023048 2.165421 4.894482 4.131418 4.562324 RASGRF2  0.580676767 0.058750841 0.046618578 4.312039929 3.024504 2.023048 2.995681 4.718672 4.131418 5.882028 FSIP2  0.574018552 0.059729834 0.048047635 4.312039929 1.874444 2.023048 2.165421 6.252746 4.131418 2.921909 SP140  0.567041929 0.060850034 0.049574685 4.312039929 1.874444 2.023048 2.165421 6.067497 4.131418 2.921909 DCP1A  0.643430759 0.051940717 0.036118408 4.311712995 5.897292 5.789702 6.056062 7.897963 8.453372 7.988762 STON1  0.601969269 0.056056571 0.042440286 4.311682298 4.815804 3.32135 3.90836 5.320955 6.861783 6.924055 CUL5  0.619522207 0.054008689 0.039515481 4.304293337 6.008206 5.661685 4.449894 7.274575 7.767462 8.053616 CREM  0.583423937 0.058208993 0.045887036 4.302217502 6.227577 6.502398 7.69729 9.767 8.332658 9.051056 UTRN  0.590048615 0.057439458 0.0446213 4.297110305 5.897292 6.537655 7.156853 8.641022 8.385634 8.997112 SNHG8  0.629688342 0.053228219 0.038134059 4.292861342 4.309025 6.184248 5.609945 8.286188 7.406567 7.668215 DHDDS  0.680833229 0.049467746 0.031572644 4.292612468 3.350997 2.023048 3.324375 5.448591 5.317867 5.426231 TMEM170B  0.601604758 0.056111267 0.042508336 4.291699032 4.209882 3.872014 4.449894 5.891233 6.551443 6.385515 TCF7  0.596947402 0.056619804 0.043361688 4.287968018 3.350997 4.389936 5.217616 6.244586 7.31791 6.32627 EPRS  0.599473707 0.056374578 0.04293297 4.275676573 3.350997 2.406905 2.995681 4.739845 5.306419 5.091834 RPP14  0.574120156 0.059716764 0.047999319 4.272972883 6.227577 5.487673 5.974145 7.835902 8.385634 7.582913 ZYG11A  0.59170848 0.057222443 0.044285131 4.26799743 3.024504 4.830496 4.754917 6.651882 5.936219 6.924055 TCEA3  0.643790551 0.05192151 0.036063967 4.257722988 5.328526 4.736586 5.702912 7.792994 7.414086 7.395512 RREB1  0.588636771 0.057508969 0.044818646 4.257579181 5.316227 6.049721 5.723602 8.139755 7.406567 7.774634 KCNMB3  0.569024334 0.06047758 0.04910854 4.251447552 4.263463 3.360637 2.165421 5.448591 5.317867 5.580533 LOC283888  0.571453164 0.060151333 0.048596121 4.245457746 1.874444 3.360637 4.449894 5.095353 6.043524 5.446557 MEGF9  0.585911991 0.05791529 0.045426335 4.242978847 6.924263 7.08238 6.769247 8.460842 9.009341 9.562759 WDR67  0.583491483 0.058208993 0.045880231 4.242400805 3.350997 2.809601 2.379345 4.894482 4.539173 5.426231 PSMD7  0.593606544 0.057018726 0.043881592 4.232149161 7.09018 6.466258 4.449894 9.171571 8.258856 7.897492 TTC27  0.655403665 0.051058737 0.034333447 4.230892705 3.819732 3.872014 3.90836 6.550689 5.920411 5.900694 ZNF620  0.597294271 0.056603505 0.043320177 4.230892705 3.819732 2.023048 2.165421 4.013424 5.317867 5.900694 LNX1  0.579383195 0.058820115 0.046841102 4.229426657 3.839948 4.389936 2.995681 7.814607 5.920411 4.790662 OBSL1  0.56542101 0.061091369 0.049867982 4.2268141 6.267718 6.03611 5.571599 7.274575 8.777924 8.11568 NUDT15  0.623783793 0.053718218 0.038901667 4.225271913 3.350997 4.80797 4.508334 6.811341 6.205902 6.587378 ASL  0.620433217 0.053986985 0.039403879 4.222334823 5.328526 5.297868 5.571599 7.109557 7.406567 8.488368 PARP6  0.585563116 0.057934468 0.045484859 4.213203065 7.355332 6.311907 6.012527 8.087444 8.928336 9.285145 EIF3A  0.602378608 0.055983853 0.042334127 4.195996346 7.956174 7.829709 7.98402 10.025188 10.307217 9.635186 SUV39H2  0.590450289 0.057353094 0.044511058 4.18606193 1.874444 3.360637 3.90836 4.739845 5.936219 5.426231 LPAR6  0.570398128 0.060316154 0.048843824 4.181467599 5.491121 6.044198 6.601009 8.665019 8.033973 7.695565 FRAT2  0.589189615 0.05748724 0.044767608 4.180049374 5.263699 2.406905 5.225216 6.857154 6.189775 7.327219 G2E3  0.57882614 0.058868113 0.046944539 4.162798874 4.682076 3.872014 5.592916 6.498222 7.53715 6.73963 SPAG16  0.683202521 0.049394421 0.031334468 4.160797452 4.963444 2.023048 5.389265 6.960054 7.187136 7.020304 REPS1  0.646438144 0.051758104 0.035666553 4.143549777 4.743564 4.351315 2.379345 6.283686 6.794431 6.129407 TNFAIP8L3  0.568560215 0.060550782 0.049244641 4.127826737 5.328526 4.351315 2.379345 6.396698 7.292524 5.580533 MACC1  0.590659894 0.057323276 0.044453896 4.119000641 5.056948 5.661685 5.217616 7.25991 7.25505 7.492252 NBPF3  0.61179168 0.05481369 0.04060769 4.098298853 3.839948 3.770995 4.449894 5.705318 7.56803 5.874974 NRN1  0.635366342 0.052679972 0.037269139 4.097356656 5.263699 4.351315 5.225216 7.25991 6.237456 9.311906 ARHGAP5  0.602091357 0.056022466 0.042396734 4.091461253 6.054828 6.072636 5.723602 8.087444 8.564762 7.582913 PLCL1  0.587073877 0.057666624 0.045119428 4.091343135 3.350997 3.32135 4.449894 6.396698 5.353925 5.900694 DNALI1  0.571517723 0.060119309 0.048560735 4.077185857 4.209882 2.023048 2.379345 6.067497 6.237456 3.676349 C12orf51  0.60944289 0.055130486 0.041034365 4.074262825 5.744513 4.413323 6.282905 7.771052 7.440337 8.232333 GEN1  0.662288615 0.050569223 0.033580129 4.067179921 5.328526 2.809601 6.072169 7.25991 8.033973 7.352555 ALG13  0.570587741 0.060307793 0.04881116 4.063509413 6.054828 7.106065 5.018694 8.051486 8.077554 8.66481 CLSPN  0.600166288 0.056344664 0.042812521 4.057634517 6.736762 6.466258 6.012527 8.033165 8.486085 9.257878 SORBS2  0.603416045 0.055822582 0.042104117 4.05595508 6.48761 5.297868 3.324375 8.447068 7.31791 7.033813 PCBP4  0.604603375 0.055686845 0.041922423 4.05516005 4.639409 4.911517 4.754917 6.395481 6.774676 7.722406 PIGA  0.572746041 0.059889668 0.048299422 4.047397101 7.410173 6.605686 5.389265 8.955085 8.4199 8.622681 RPS14  0.573602117 0.059795609 0.04813542 4.041384257 6.417969 7.0089 6.704285 9.410337 8.220489 8.719135 RAB6B  0.685857125 0.049293152 0.031073154 4.034732995 4.639409 4.80797 2.165421 6.651882 6.640994 6.722123 FKBP1B  0.567081452 0.060825097 0.049544743 4.033551695 4.639409 4.413323 3.90836 6.339437 5.920411 6.739863 KLHDC10  0.63026408 0.053186878 0.038063967 4.028162114 5.779429 5.809601 4.724406 7.70315 7.819723 7.582913 FEZ2  0.635772622 0.052614987 0.037186798 4.018146841 6.143785 5.661685 2.995681 7.477873 7.68534 7.668215 DDX58  0.575883006 0.059377251 0.047522286 4.004046935 5.779429 6.092406 6.704285 7.631894 8.564762 8.705744 SLC37A3  0.590114799 0.057429321 0.044597482 3.999629121 5.753024 5.809601 6.056062 7.582358 8.055928 8.010706 TFAP2B  0.575492814 0.059485925 0.047656346 3.990352321 3.819732 3.32135 2.165421 5.743334 5.317867 4.790662 ZNHIT2  0.574115961 0.059723631 0.048014291 3.990352321 3.350997 3.32135 2.379345 6.395481 5.317867 4.146207 RALGPS2  0.61903513 0.054100449 0.039623682 3.981996143 3.350997 2.809601 3.324375 7.243046 5.317867 4.476242 INADL  0.58608689 0.057856068 0.045331745 3.973507129 5.700376 5.362142 3.324375 7.450526 6.640994 7.352555 LOC100652768  0.648439971 0.051584246 0.035290915 3.973404729 1.874444 2.023048 2.165421 4.013424 6.205902 3.676349 C14orf1  0.64776718 0.051631895 0.035422933 3.973404729 2.201691 2.023048 2.165421 4.013424 5.317867 4.146207 COL6A5  0.591458225 0.057236297 0.044321878 3.973404729 1.874444 2.023048 2.165421 4.013424 4.608763 3.676349 SHISA2  0.586265489 0.05781824 0.045286152 3.973404729 1.874444 2.023048 2.379345 4.013424 5.165949 3.630092 LYSMD3  0.608071352 0.055241507 0.041263695 3.968523126 5.856559 2.809601 4.944468 6.857154 7.845161 6.587378 NHSL1  0.600633724 0.056295567 0.042728139 3.947082503 3.024504 2.809601 2.165421 4.739845 6.043524 4.146207 FRMD6-AS1  0.622087085 0.053826336 0.039192923 3.918249241 6.054828 5.661685 6.012527 7.631894 7.96603 8.906373 RSBN1  0.620213272 0.054006231 0.039441987 3.916354682 6.306772 3.360637 6.326717 8.139755 8.296229 7.46072 GMPR2  0.606714338 0.055431478 0.041528411 3.915893432 5.779429 5.195784 6.054038 7.748771 7.942653 7.695565 ITGBL1  0.612987097 0.054692088 0.040481116 3.906827387 2.201691 2.023048 2.165421 5.743334 4.131418 3.630092 WAC  0.6092432 0.055148494 0.041089486 3.900125105 6.736762 5.362142 7.030042 8.700282 8.777924 8.503924 PHACTR2  0.572131382 0.060021442 0.048443688 3.89375811 7.563198 6.092406 6.737132 8.033165 9.524361 9.494312 ARMC1  0.653370237 0.051215566 0.034610412 3.892864931 5.779429 5.43468 3.324375 7.70315 7.292524 7.395512 RELN  0.587735386 0.057632378 0.045010548 3.891477272 3.024504 3.360637 4.285996 5.320955 9.237827 4.476242 CFB  0.566846512 0.06087149 0.049611432 3.891100309 6.736762 4.413323 4.754917 8.087444 6.373501 8.622681 GPANK1  0.615000146 0.054502508 0.04020279 3.850211746 6.417969 4.750708 6.012527 7.957464 7.89473 8.232333 KCMF1  0.57516633 0.059559002 0.047774073 3.839185479 6.846868 7.152299 7.056312 9.02165 8.804107 8.997112 MGAT4A  0.579004903 0.058854512 0.04690575 3.825427973 4.682076 4.351315 4.449894 7.957464 5.857745 6.385515 SERPINB9  0.585685893 0.057930543 0.045465805 3.821381246 10.604984 10.20576 10.772767 12.38198 12.706861 12.50728 TLL2  0.590011284 0.057439458 0.044628105 3.809832667 2.201691 2.809601 2.165421 4.013424 4.131418 5.874974 LRRC8C  0.591835555 0.057215069 0.044261313 3.783982989 4.263463 4.750708 4.285996 7.582358 6.205902 6.129407 CYB5B  0.572590947 0.059927693 0.048339571 3.768903211 5.263699 6.03611 3.324375 7.177844 7.473335 6.931222 SNRPC  0.590231225 0.057400709 0.044566179 3.701602063 6.678389 6.228068 3.764125 8.566539 7.989035 7.523109 GALC  0.617867746 0.054205948 0.039778156 3.673026868 6.344798 2.023048 5.217616 6.960054 7.094585 7.988762 CCDC101  0.595230882 0.056765675 0.043561075 3.649965238 4.682076 4.80797 5.225216 6.664985 6.549959 8.340256 ZCCHC4  0.56927702 0.060422443 0.049025519 3.561712927 8.096549 8.203594 7.580498 9.513069 9.872512 10.838349 NID2  0.575358554 0.059548053 0.047722355 3.557804272 4.963444 2.023048 3.764125 5.579836 6.794431 5.580533 TUSC3  0.587760847 0.057632378 0.045003743 3.521519007 5.263699 5.661685 5.217616 7.074163 8.764653 7.033813 GTF3C5  0.58399387 0.058125809 0.045763865 3.479414259 6.054828 6.139057 4.754917 7.937902 7.167462 7.695565 PIGG  0.573525978 0.059795609 0.04816264 3.452363084 6.924263 6.311907 4.508334 8.711848 7.989035 7.920856 RPL10A  0.581875712 0.058472442 0.046268118 3.411624816 11.664076 12.12893 12.102905 13.796321 13.434535 15.373863 FAM122C  0.568777241 0.060487245 0.049183396 3.376191033 3.350997 2.023048 3.764125 5.095353 5.353925 5.106393 CDCA4  0.57971865 0.058818437 0.046811841 3.307690635 4.263463 2.023048 3.90836 5.891233 5.509998 5.634184 CYP4Z2P  0.607836375 0.055264045 0.04132426 3.24199663 1.874444 2.023048 2.165421 6.396698 3.571326 3.676349 CENPK  0.599416654 0.056374578 0.042939775 3.24199663 1.874444 2.023048 2.165421 6.283686 3.571326 3.630092 PKD1L2  0.592339152 0.057117807 0.044123171 3.24199663 1.874444 2.406905 2.165421 7.037879 3.571326 3.630092 HNF4G  0.580986915 0.058713636 0.04652671 3.24199663 1.874444 2.023048 2.165421 5.743334 3.571326 3.630092 CENPE  0.580439718 0.058778844 0.046669616 3.24199663 1.874444 2.023048 2.165421 5.728038 3.571326 3.630092 CLCA4  0.580086959 0.058796241 0.046731541 3.24199663 1.874444 2.023048 2.165421 5.579836 3.571326 3.676349 C5orf27  0.575242321 0.059556798 0.047748214 3.24199663 1.874444 2.023048 2.165421 5.448591 3.571326 3.676349 EFNA3  0.575242321 0.059556798 0.047748214 3.24199663 1.874444 2.023048 2.165421 5.448591 3.571326 3.676349 TLR3  0.565308078 0.061121202 0.049902007 3.24199663 1.874444 2.023048 2.165421 5.320955 3.571326 3.630092 NUB1  0.580812511 0.058735678 0.046587955 3.138230176 4.963444 2.406905 5.389265 6.395481 6.613395 7.03218 SERPINA6  0.577062955 0.059160521 0.047280708 2.160672033 1.874444 2.023048 2.165421 9.111713 3.134528 2.921909 FGFR3 −0.576789682 0.059216257 0.047343995 0.163236674 6.186289 7.197097 9.451056 6.396698 3.571326 5.091834 PBX3 −0.599921695 0.056344664 0.042845185 0.119069371 5.335413 6.877454 7.422239 6.183122 2.265287 2.921909 GAL −0.727832119 0.047482522 0.027284791 0.007044643 2.201691 10.779349 11.920956 2.820813 4.608763 3.630092 TMEM80  0.672786463 0.049933984 0.032385846 −0.026302331 1.874444 2.023048 2.165421 1.661149 7.414086 7.36177 LRRC17  0.64985539 0.051486266 0.035062266 −0.029490783 3.024504 3.770995 3.324375 2.820813 9.075328 8.407967 LGALSL  0.665988758 0.050345474 0.033176591 −0.029738234 1.874444 2.023048 2.379345 1.661149 7.094585 7.897492 NPR2  0.641775885 0.05203621 0.036300102 −0.031497751 1.874444 2.406905 2.165421 1.661149 7.25505 7.395512 WIF1  0.589244536 0.05748724 0.044749915 −0.034273582 1.874444 3.872014 2.165421 1.661149 8.928336 7.03218 C16orf89  0.636463843 0.052578532 0.037119428 −0.036863019 1.874444 2.023048 2.165421 1.661149 6.78473 7.180104 CALN1  0.620957766 0.053929257 0.039344675 −0.041666207 1.874444 2.023048 2.165421 1.661149 6.608026 7.020304 IFLTD1  0.609022918 0.055156748 0.041134399 −0.042490899 1.874444 2.023048 2.165421 1.661149 6.640994 6.722123 SULT1A2  0.628163313 0.053354225 0.038376318 −0.043377436 1.874444 2.023048 2.165421 1.661149 6.549959 7.255535 RASL11A  0.623353924 0.053779735 0.038981967 −0.046316877 1.874444 2.023048 2.165421 1.661149 7.25505 6.455366 VTRNA2-1  0.629909118 0.053198883 0.038087785 −0.047876504 1.874444 2.809601 2.165421 1.661149 6.549959 8.719135 YAE1D1  0.588212226 0.057572401 0.044936373 −0.050652503 1.874444 2.023048 2.165421 1.661149 6.608026 6.32627 FLJ37453  0.622690765 0.053781042 0.039090167 −0.053868742 1.874444 2.023048 2.165421 1.661149 6.237456 7.523109 CFI  0.596638643 0.056634604 0.043397754 −0.055059899 1.874444 2.023048 2.165421 1.661149 6.205902 6.931222 TTC12  0.581098682 0.058657474 0.046470228 −0.055059899 1.874444 2.023048 2.165421 1.661149 6.205902 6.587378 WDR53  0.581098682 0.058657474 0.046470228 −0.055059899 1.874444 2.023048 2.165421 1.661149 6.205902 6.587378 GSTM5  0.642211142 0.052001547 0.036234774 −0.05547041 1.874444 2.023048 2.165421 1.661149 8.119857 6.195186 LINC00518  0.574174081 0.059709894 0.047984348 −0.058984802 1.874444 2.023048 2.165421 1.661149 6.549959 6.106561 LOC91948  0.592357428 0.057117807 0.044116366 −0.061619223 1.874444 2.023048 2.165421 1.661149 6.043524 7.033813 SPAST  0.648382924 0.051597178 0.035309289 −0.066674675 3.024504 2.406905 2.165421 2.820813 6.794431 6.931222 OLFML1  0.575704501 0.059399513 0.047556312 −0.069255582 1.874444 2.023048 2.165421 1.661149 6.861783 5.874974 TGFBR3  0.570629624 0.060307793 0.04879755 −0.092706724 9.869873 5.297868 6.670675 9.030914 10.697795 10.101857 ZNF688  0.736142769 0.047245915 0.026677782 −0.106653489 5.316227 2.023048 2.165421 5.252045 6.373501 7.943848 FOPNL  0.622816817 0.053781042 0.039069752 −0.110577208 4.263463 3.872014 2.165421 4.013424 7.440337 7.291822 FAM110D  0.586513181 0.057769858 0.045227628 −0.124954205 1.874444 2.406905 2.165421 1.661149 5.165949 9.08248 KLHL8  0.578405248 0.05896564 0.047031643 −0.129992093 4.639409 2.809601 2.995681 4.013424 6.549959 7.582913 YIF1A  0.639174717 0.052364413 0.036694794 −0.130537464 6.417969 4.750708 2.995681 6.063041 7.56803 9.355434 EIF2B3  0.655860976 0.050993826 0.034281728 −0.14994268 4.815804 3.32135 2.995681 4.739845 7.269549 7.553321 C1RL  0.684544018 0.049333995 0.031214018 −0.170370622 4.963444 2.406905 2.165421 4.718672 6.794431 7.03218 FAM214B −0.568981915 0.060479768 0.04912147 −2.723567075 8.653654 7.530398 8.553333 1.661149 7.107836 7.255535 EPB41 −0.570984743 0.060259921 0.048741068 −2.743862666 6.949166 7.829709 6.976024 1.661149 6.373501 5.634184 RAB3IL1 −0.565166666 0.061148989 0.049946921 −2.789317281 8.129608 7.77165 8.407885 1.661149 7.440337 6.649696 CHRD −0.577509021 0.05912348 0.047232392 −3.10182488 8.183076 7.815412 8.355951 1.661149 6.549959 7.428484 SLC6A6 −0.66170494 0.050579662 0.033627084 −3.137150692 8.264707 8.214531 8.257481 1.661149 6.608026 6.73963 ELOVL6 −0.622646088 0.053781042 0.039096972 −3.349002317 6.344798 6.270596 6.282905 1.661149 4.539173 4.790662 CTSL1 −0.568872007 0.060479768 0.049147329 −3.442360216 11.56685 12.044102 12.220114 8.173604 10.260704 10.561895 NDOR1 −0.584765016 0.058064889 0.045669956 −3.473764818 8.653654 8.136169 8.407885 6.857154 4.797798 6.69026 USP40 −0.57011814 0.06033194 0.048888057 −3.487642935 8.831618 8.586982 8.477589 5.320955 6.78473 7.255535 MOB2 −0.566062255 0.061004458 0.049758421 −3.489675192 9.242593 9.342669 9.721163 7.918071 6.189775 7.748756 B3GALT4 −0.580161257 0.058796241 0.046724736 −3.534864559 4.743564 4.911517 4.508334 1.661149 3.134528 2.921909 FRMD6 −0.602425223 0.055983853 0.042327322 −3.536195015 10.70342 11.09115 10.815695 8.993498 9.749902 5.882028 DPP7 −0.602451938 0.055981204 0.042312351 −3.544312275 9.566109 9.281572 9.353784 6.063041 7.740604 7.582913 RPP25 −0.565434701 0.061091369 0.049861177 −3.555533586 5.316227 5.195784 6.369239 1.661149 4.539173 3.630092 LINC00341 −0.584662694 0.058076564 0.045688329 −3.632620804 8.996009 8.509169 9.583416 4.894482 7.191402 7.722406 LOC100130776 −0.569041988 0.060471767 0.04909425 −3.67753789 7.04469 6.391145 5.702912 1.661149 5.165949 4.790662 REXO2 −0.565212718 0.061131857 0.049920381 −3.690709425 10.991122 10.797649 10.616004 8.94532 9.107223 8.534542 DISP1 −0.667001664 0.050336605 0.033113984 −3.72278708 7.530567 7.631788 7.273415 1.661149 5.920411 5.634184 ALDH1A2 −0.607221087 0.055354487 0.041418169 −3.762813805 8.214232 8.561508 10.172278 1.661149 8.764653 6.649696 SLC7A8 −0.571389136 0.060168186 0.048619258 −3.762877996 9.372557 7.218985 8.66852 1.661149 7.187136 7.46072 FBXL19 −0.609188432 0.055155203 0.041105138 −3.783692356 5.491121 5.789702 5.389265 1.661149 3.571326 4.146207 QRSL1 −0.57304166 0.059837281 0.048247703 −3.797579367 10.112425 10.575983 10.175278 7.679787 8.4199 8.650903 RASA4P −0.582242473 0.058409447 0.046190541 −3.799598273 8.720278 7.800972 9.708794 1.661149 6.794431 8.440667 NCAPD3 −0.596272099 0.056676183 0.043438585 −3.803739422 6.765086 7.033812 5.974145 4.894482 2.265287 5.106393 DPF2 −0.61906709 0.054100449 0.039616876 −3.804633769 9.4134 9.104741 9.197307 5.579836 7.269549 7.668215 EN2 −0.569051152 0.060471767 0.049087445 −3.823401085 6.306772 7.033812 7.855267 1.661149 5.920411 5.634184 TEP1 −0.570590603 0.060307793 0.048804355 −3.880658028 8.69841 8.988481 8.063885 5.252045 6.861783 7.03218 RPLP0 −0.602681381 0.055954239 0.04225655 −3.900372297 16.262427 15.918147 15.946254 14.042609 13.451719 14.298816 POLL −0.628527804 0.053328876 0.038319156 −3.933651071 7.800655 7.197097 7.227914 5.252045 5.920411 3.630092 ANPEP −0.609512784 0.055120848 0.041007826 −3.943214556 10.757297 10.094707 9.930946 6.664985 8.777924 8.194487 SPRY2 −0.573270705 0.059824474 0.048211637 −3.951334389 11.113223 9.410824 10.06638 8.173604 8.436733 7.428484 ATAT1 −0.661768665 0.050579662 0.033620279 −3.952900832 8.096549 7.857885 7.295639 1.661149 6.319269 5.874974 RBM23 −0.591067961 0.05728668 0.044396053 −3.958050799 10.499337 9.905188 9.68794 7.70315 8.160956 8.010706 CPSF3L −0.609092228 0.055156748 0.041127594 −4.03794869 10.047596 9.401283 8.829514 4.894482 8.033973 7.553321 RNF208 −0.594325927 0.056918505 0.043741409 −4.066606802 6.58615 6.060401 5.225216 1.661149 4.131418 4.562324 SGIP1 −0.605577374 0.055588631 0.041762504 −4.074903319 7.278811 6.060401 6.282905 5.252045 2.265287 4.476242 TEKT4 −0.568908733 0.060479768 0.049132358 −4.184566636 9.159663 9.013748 7.557139 6.395481 7.094585 5.580533 EHD1 −0.597544631 0.056527426 0.043235114 −4.19220442 9.422322 10.262196 9.332443 6.498222 7.505595 8.194487 ATP6V0E1 −0.622274721 0.053817472 0.039171147 −4.21009182 11.026657 10.885817 10.774746 8.811966 9.086038 8.32282 PDCD11 −0.574360779 0.059672428 0.047935352 −4.223792773 7.956174 8.464054 7.519866 6.283686 4.608763 6.385515 MANF −0.587026465 0.057671126 0.045141204 −4.223855652 11.239738 9.867571 9.431116 8.331873 8.077554 7.352555 KHNYN −0.578119083 0.059023503 0.047105818 −4.228937815 10.300784 10.821096 10.459924 8.331873 8.220489 8.952456 FNIP1 −0.579344147 0.058828079 0.046856754 −4.233806643 9.60972 8.731048 9.619106 6.811341 7.53715 7.36177 MLXIP −0.602275451 0.056009923 0.042369513 −4.259749299 8.183076 9.271133 9.455998 7.36523 6.613395 6.129407 CHCHD2 −0.571697263 0.060090644 0.048528071 −4.301434465 11.901113 12.110017 10.885132 8.447068 9.796295 10.044503 SLC2A1 −0.580226996 0.058778844 0.046687309 −4.302967122 9.470427 9.533816 8.387335 6.814118 6.78473 7.428484 ASB1 −0.583175169 0.058250261 0.045956448 −4.310066694 8.151234 7.458616 7.519866 5.320955 6.043524 5.580533 SYNGR3 −0.604215777 0.055732254 0.041995917 −4.316452007 4.309025 3.770995 6.012527 1.661149 2.265287 2.921909 NOC2L −0.575657175 0.059408169 0.047572644 −4.328544045 8.351337 9.162364 7.422239 6.544171 6.237456 5.580533 CCDC167 −0.584934938 0.058034601 0.045627765 −4.335165004 8.583805 7.991061 7.381261 5.743334 6.043524 5.874974 GNL2 −0.595383637 0.056763192 0.043543382 −4.348124552 7.730559 9.239354 8.187891 6.067497 6.551443 5.900694 LRFN4 −0.5735611 0.059795609 0.048155835 −4.355784173 5.753024 7.174872 6.056062 4.739845 4.131418 3.630092 ANKRD13D −0.621531015 0.053903339 0.039267778 −4.367534819 8.450608 8.278469 7.870154 5.743334 5.857745 6.455366 FIBP −0.57100888 0.060259921 0.048734263 −4.375087473 10.095792 9.568332 9.149294 6.396698 7.91889 7.96648 RNF123 −0.582948922 0.058281216 0.046006125 −4.379052629 9.545842 8.738645 8.257481 6.244586 6.608026 7.218312 TRIM11 −0.702114965 0.048553714 0.029631848 −4.384570123 8.214232 7.991061 8.175959 1.661149 6.043524 6.587378 C15orf57 −0.591444124 0.057236297 0.044328683 −4.384950817 7.716122 8.016282 7.227914 5.095353 5.353925 6.106561 CRTC3 −0.781400954 0.045776109 0.023239878 −4.394512506 10.336619 10.219399 10.479473 1.661149 8.200916 8.407967 AGAP3 −0.64570215 0.051818705 0.035806737 −4.396126486 9.991752 9.327635 8.896486 7.918071 7.191402 5.106393 CYBASC3 −0.65972574 0.050702199 0.033812862 −4.40160937 9.533543 8.731048 8.677011 5.026959 6.640994 7.395512 PRDM1 −0.675997116 0.049752474 0.032078258 −4.40440939 10.139728 9.931942 12.60146 7.792994 8.220489 8.340256 CXXC1P1 −0.568830644 0.060479768 0.049160939 −4.421238185 7.298325 6.311907 7.250844 1.661149 6.189775 5.106393 PDGFA −0.577969844 0.059048459 0.04713508 −4.439705556 9.201724 7.912639 7.7303 5.579836 6.774676 5.874974 PRDM11 −0.583195594 0.058250261 0.045949643 −4.46476327 3.819732 4.413323 5.217616 1.661149 2.265287 2.921909 C9orf114 −0.647329836 0.05166843 0.035498469 −4.468758627 8.415295 8.34965 8.211462 5.743334 6.189775 6.385515 PPP3CB −0.697299524 0.04880813 0.030095271 −4.47636582 7.480194 7.512784 6.800663 1.661149 5.317867 5.426231 PTGES −0.645600071 0.051818705 0.035813542 −4.491032974 11.951287 8.833929 8.562528 6.395481 7.473335 7.033813 RXRB −0.583919886 0.058126643 0.045776114 −4.50190949 9.558037 9.2447 9.692135 7.074163 7.269549 7.96648 CRAT −0.655960057 0.050993826 0.034261313 −4.502039668 10.643643 8.124619 7.913913 5.743334 6.205902 6.587378 C15orf61 −0.604377794 0.055717618 0.041954406 −4.506861268 9.206896 9.327635 9.316227 7.144104 7.89473 5.900694 FAM173A −0.594917911 0.056842436 0.043637972 −4.512025364 7.480194 7.218985 7.746525 1.661149 5.306419 6.924055 MEN1 −0.585027669 0.058022045 0.04560871 −4.537939495 8.69841 7.129367 7.762571 5.579836 5.936219 5.580533 FOXP4 −0.575135251 0.059559002 0.047787683 −4.541195121 7.497182 8.436292 8.246113 6.063041 5.936219 6.106561 DEGS1 −0.69182375 0.048955004 0.030531473 −4.543057025 6.792865 6.792427 6.704285 1.661149 4.608763 5.091834 LOC100127983 −0.652882114 0.051234373 0.034694794 −4.567929706 7.701538 8.089403 8.994854 6.067497 5.509998 6.051818 ZNF668 −0.716835922 0.047841399 0.02818986 −4.569168271 7.298325 7.152299 7.401896 1.661149 5.509998 5.106393 ACO1 −0.574424911 0.059635779 0.047887036 −4.609342261 8.756004 7.174872 7.317525 5.743334 6.551443 3.676349 MXD3 −0.666897298 0.050336605 0.033141204 −4.616983956 7.841135 8.101237 7.250844 6.067497 3.134528 5.634184 CUL4A −0.644291042 0.051917117 0.035996597 −4.632245334 10.169176 10.563205 10.538909 7.957464 8.098861 8.549611 TFRC −0.661127619 0.050645852 0.033688329 −4.636853604 9.952259 10.919629 10.245467 8.156778 7.942653 8.03232 CAPN2 −0.623115156 0.053781042 0.039007826 −4.670548012 8.831618 9.302226 8.011136 4.894482 6.608026 7.152205 SPSB2 −0.593755822 0.057016532 0.043861858 −4.67310745 7.317579 5.661685 6.355801 1.661149 4.131418 5.580533 SRCRB4D −0.606109987 0.055492203 0.041652943 −4.678913342 3.819732 5.148082 4.724406 1.661149 2.265287 2.921909 FAM176B −0.570211662 0.06033194 0.048866962 −4.679309221 11.496784 10.775662 10.352707 7.70315 8.549366 9.704151 ANKH −0.575143685 0.059559002 0.047780878 −4.693670452 8.661211 9.659201 10.496363 7.394225 7.505595 7.428484 MAPK8IP3 −0.671400608 0.050012479 0.032561415 −4.704546717 9.099752 8.170275 9.041632 6.067497 5.936219 6.931222 MLXIPL −0.711055131 0.048062795 0.028683906 −4.710934525 6.48761 7.033812 7.339085 1.661149 4.797798 5.106393 RAB6A −0.637829568 0.052501106 0.036950663 −4.720057872 8.096549 6.762934 6.564874 1.661149 5.857745 5.091834 SYN1 −0.625239843 0.053566177 0.038732222 −4.733957223 4.682076 4.413323 4.508334 1.661149 2.265287 2.921909 GLYCTK −0.65534822 0.051064299 0.034357264 −4.747642027 6.792865 4.389936 3.90836 1.661149 2.265287 2.921909 PLCH2 −0.578241219 0.05899939 0.047077237 −4.747642027 4.263463 5.195784 3.90836 1.661149 2.265287 2.921909 PRAF2 −0.569125298 0.060463488 0.049068391 −4.747642027 5.658609 4.830496 3.90836 1.661149 3.134528 2.921909 RIC8A −0.587053667 0.057668875 0.045130316 −4.770031992 9.823483 8.862025 8.12722 6.067497 6.608026 7.36177 MTMR10 −0.648227273 0.051597178 0.035316094 −4.77197455 9.689484 8.805276 9.321653 6.550689 7.505595 6.722123 UCN −0.622308965 0.053817472 0.039164342 −4.772474169 6.554045 5.195784 5.389265 1.661149 3.134528 4.562324 ITGB7 −0.583504539 0.058208993 0.045873426 −4.790156046 6.227577 7.965391 9.729351 5.705318 4.131418 6.32627 GALNT2 −0.800559348 0.045343936 0.02195917 −4.806416557 9.483274 9.327635 9.431116 1.661149 7.174648 7.218312 SF3B2 −0.615893984 0.054401265 0.040085063 −4.831939486 11.625003 11.283907 10.529562 9.352401 8.842512 8.534542 LOC401164 −0.614643103 0.054543342 0.040253828 −4.836867155 4.309025 5.809601 3.935222 1.661149 2.265287 2.921909 TCHP −0.59182425 0.057215069 0.044268118 −4.857941559 8.085359 8.454859 8.323869 6.811341 6.043524 5.634184 YRDC −0.642820371 0.05195198 0.03617557 −4.865336645 8.535285 8.124619 7.746525 6.252746 6.205902 4.562324 SLC43A1 −0.60262496 0.055959634 0.042269479 −4.870270968 7.730559 6.957749 8.246113 5.743334 5.165949 5.446557 PRRT1 −0.634982267 0.052738117 0.037340592 −4.878883462 6.417969 6.228068 6.891005 1.661149 4.131418 5.446557 JAGN1 −0.593237853 0.057040543 0.043943518 −4.918509885 10.006659 8.988481 8.175959 6.664985 7.094585 6.69026 SLC22A23 −0.653432031 0.051215566 0.034596802 −4.928850497 10.223779 8.158996 8.279951 6.954147 5.857745 6.051818 ABCF1 −0.639012375 0.052378804 0.036713168 −4.969612481 10.452202 10.7211 9.733427 7.631894 7.96603 8.407967 KAT6A −0.639563375 0.052338861 0.036636951 −4.977947379 10.969981 11.183109 11.570693 8.566539 8.867558 9.478651 GNB2 −0.641549436 0.052091702 0.036347057 −4.988655315 12.794595 12.085651 11.915585 9.767 9.540026 10.508909 C15orf17 −0.650095297 0.05147219 0.035028241 −4.990603984 9.444387 9.538176 9.537526 7.70315 6.774676 7.218312 IDUA −0.578980687 0.058859047 0.04691868 −5.031229045 8.971905 9.614482 10.75483 7.531061 6.640994 8.32282 MAFK −0.630933521 0.053142215 0.037914257 −5.034554561 9.722364 10.106499 11.138237 8.433162 7.740604 7.774634 C12orf10 −0.598826989 0.056432998 0.043061586 −5.040235359 11.638464 10.986561 10.809916 8.65307 8.140553 9.832914 FBLN5 −0.598565997 0.056432998 0.043083362 −5.045942424 11.343187 10.71726 12.377524 7.36523 10.446718 9.008063 UBE4B −0.672514052 0.049933984 0.032433481 −5.072413739 10.922037 11.33617 11.042912 8.993498 8.564762 8.870819 UGGT2 −0.575483844 0.059485925 0.047663151 −5.08670682 8.57583 7.598777 6.012527 5.252045 4.539173 5.446557 INTS12 −0.673096586 0.049933984 0.03236475 −5.087321842 8.831618 9.06903 8.163928 5.095353 6.549959 6.722123 MCM2 −0.647374555 0.051665552 0.035485539 −5.094660747 7.943836 6.957749 6.410545 5.026959 4.608763 4.476242 UPK3B −0.580180648 0.05878341 0.046700238 −5.112909273 8.824905 8.23616 8.598731 6.244586 5.306419 7.395512 PLXNA1 −0.662109739 0.050577128 0.033609391 −5.122000005 8.424205 9.239354 9.68794 6.067497 7.53715 6.129407 AAMP −0.678631703 0.049556832 0.031763865 −5.122872886 9.3863 9.511817 9.431116 7.074163 7.505595 6.69026 RCC2 −0.623918296 0.053698943 0.038879211 −5.132570673 7.410173 11.863059 8.234655 5.579836 7.269549 5.874974 PHF1 −0.594649638 0.056878376 0.043683566 −5.135863496 11.844989 10.407489 12.472651 8.206677 9.179013 10.112044 PTK7 −0.73893081 0.04712834 0.026470908 −5.138013217 8.535285 8.969237 8.642743 4.718672 6.608026 6.32627 PPP3CC −0.638739155 0.05242235 0.036779857 −5.145941818 10.177104 9.457608 9.028421 6.664985 7.25505 7.695565 ANKRD9 −0.694702932 0.048858998 0.030287173 −5.148142055 9.301804 9.013748 8.448127 6.954147 5.165949 6.649696 DGKZ −0.621476081 0.053903339 0.039274583 −5.156807651 8.638422 9.007473 9.209064 7.504712 6.640994 5.634184 RNF145 −0.649575969 0.051507311 0.03510786 −5.158148094 10.54906 10.550312 11.118111 7.748771 8.751258 8.692228 ZBTB39 −0.687394781 0.049147961 0.030871725 −5.172921877 6.648293 6.502398 5.702912 1.661149 4.131418 4.476242 ADCYAP1R1 −0.618855407 0.054111443 0.03964886 −5.196471994 9.316235 8.445606 10.144994 4.894482 7.767462 7.352555 CCND2 −0.606613004 0.05543975 0.041543382 −5.19730322 10.969981 10.58444 11.75943 8.206677 9.74315 8.407967 IL32 −0.668178778 0.050279153 0.0329459 −5.200125752 10.024346 9.96146 9.343153 7.918071 6.237456 7.582913 LDLRAP1 −0.629531067 0.053240793 0.038153113 −5.200883296 7.786906 8.299167 6.056062 1.661149 5.920411 5.580533 CYHR1 −0.653986962 0.051134477 0.034521946 −5.209849475 8.43306 7.615377 8.089553 5.026959 5.936219 6.051818 LDB1 −0.720286737 0.047703746 0.027910174 −5.210458242 8.535285 8.595375 9.556058 1.661149 7.174648 6.924055 ACTR1A −0.651311251 0.051429843 0.03493297 −5.210581399 9.946086 8.99484 8.598731 5.728038 6.613395 7.582913 LOC401588 −0.648011013 0.051631895 0.03537802 −5.220007999 7.773024 6.060401 7.611303 5.743334 4.131418 3.676349 WIPI2 −0.667909389 0.050279153 0.032984008 −5.24693146 10.392166 9.974387 10.003631 7.976765 7.96603 7.582913 SAMD4A −0.630396584 0.053156193 0.038018374 −5.256154244 8.720278 9.821812 10.568875 7.582358 7.767462 6.32627 ADAMTS7 −0.660122936 0.050684199 0.033763185 −5.25728583 5.316227 4.351315 4.508334 1.661149 2.265287 2.921909 QSOX1 −0.655050998 0.051064299 0.034379721 −5.258507599 10.174466 10.896044 9.945076 8.501391 8.258856 6.618407 ASF1A −0.727695934 0.047495226 0.027316774 −5.271343058 9.170294 8.896392 9.112206 6.498222 6.78473 6.587378 COPS7B −0.57668063 0.059225813 0.047361007 −5.288355045 6.417969 3.872014 5.974145 1.661149 3.571326 3.676349 AKIRIN2 −0.669995807 0.050073072 0.032711807 −5.298768867 11.244777 11.22833 11.79692 8.822673 9.158864 9.320717 TUBB2B −0.622545257 0.053781042 0.039110582 −5.298878631 8.254752 9.145317 8.355951 5.448591 6.608026 6.73963 LOC283174 −0.610159044 0.055042551 0.040923443 −5.32766668 5.335413 7.197097 5.702912 4.013424 4.131418 2.921909 RANBP9 −0.622580417 0.053781042 0.039103777 −5.340668765 10.649353 9.905188 10.939077 8.222933 8.4199 8.232333 CALU −0.633613062 0.052913654 0.037556992 −5.346445143 12.926253 11.521536 11.990733 9.102956 9.866312 10.302002 LOC100216545 −0.581635178 0.058531256 0.04632392 −5.355484142 7.579241 6.762934 7.825025 4.341916 4.539173 6.385515 BAZ1B −0.739889804 0.047086482 0.026394012 −5.361777882 10.266516 10.456685 10.736668 7.877571 8.033973 8.053616 FCHO2 −0.620173798 0.054006231 0.039455597 −5.366123891 5.982974 6.049721 7.7303 1.661149 5.306419 4.476242 PHPT1 −0.584243738 0.058116747 0.045747533 −5.375688476 11.356048 11.126325 10.088827 8.65307 8.624754 8.929599 SOBP −0.803184742 0.045338539 0.021855733 −5.3835207 9.553983 9.466786 10.298708 1.661149 7.870158 7.218312 HEATR7A −0.665381641 0.050389557 0.033239878 −5.389365281 7.671922 8.388801 7.227914 5.728038 4.797798 5.446557 YTHDC1 −0.620821895 0.053957661 0.039373937 −5.392162439 12.142253 11.711095 12.738081 10.174762 10.307217 9.276113 SEC31A −0.710515588 0.048141008 0.028752637 −5.399119543 12.964166 12.567371 12.463477 9.778045 10.531442 10.233665 AMOTL1 −0.705928655 0.048355462 0.029248044 −5.4111228 9.562079 9.767145 10.309671 5.026959 7.845161 7.873743 DENND5A −0.707841206 0.048268527 0.029021436 −5.416418426 10.874072 10.609516 11.314569 9.058353 8.436733 7.218312 G3BP1 −0.714814255 0.047877006 0.028338891 −5.429613022 10.668227 10.711481 11.38104 8.361545 8.94019 7.523109 CENPO −0.67016014 0.050073072 0.032705002 −5.435393982 8.415295 7.952383 7.4423 5.252045 5.509998 5.882028 PQBP1 −0.715057074 0.047877006 0.028304866 −5.438554222 10.861007 10.682232 10.371139 8.239009 8.140553 8.287303 TUSC1 −0.68768578 0.049147961 0.030844505 −5.46822029 11.023729 10.082818 10.440106 6.252746 7.989035 8.929599 PGRMC1 −0.656238279 0.050993826 0.034236815 −5.471894209 11.344361 12.34279 12.202577 8.745998 10.047106 9.750536 STEAP1 −0.662901348 0.050504642 0.033478054 −5.48499336 10.707075 8.841005 8.163928 6.244586 7.066159 6.385515 METTL17 −0.700188684 0.048716465 0.029853692 −5.486180102 10.963884 11.082221 10.32596 8.361545 7.870158 8.66481 OTUD7B −0.725543864 0.047551011 0.027454236 −5.500903441 8.493568 8.23616 8.334642 5.320955 6.237456 5.874974 TMEM204 −0.644228499 0.051917117 0.036003403 −5.512579185 11.072716 8.949732 9.374815 1.661149 8.609988 8.32282 SLC44A1 −0.643459532 0.051940717 0.036111603 −5.525143657 11.210423 9.659201 10.40986 7.835902 8.350533 7.943848 CNIH4 −0.587354383 0.057642811 0.045064308 −5.530294582 6.099991 4.911517 5.389265 1.661149 4.539173 2.921909 CAPN5 −0.637235706 0.052514975 0.037033004 −5.548106696 7.336579 6.311907 6.948237 1.661149 5.857745 4.476242 FAM89B −0.617512672 0.054225734 0.03983736 −5.563615815 9.099752 9.686953 9.542181 6.550689 7.066159 7.920856 ATP8B2 −0.622840508 0.053781042 0.039062947 −5.591518861 9.927407 8.101237 9.1735 5.728038 7.406567 6.69026 CMIP −0.659950267 0.050684199 0.03376999 −5.617591086 10.499337 12.374223 10.432604 8.768324 7.942653 8.822008 ABU −0.580726003 0.058750841 0.046611773 −5.620163214 10.643643 11.152155 10.992779 9.716222 8.502167 8.03232 ZNF592 −0.633699863 0.052882301 0.03752637 −5.6439882 9.663383 9.104741 9.66678 7.918071 6.608026 6.942983 PSD −0.635567348 0.05262489 0.037218782 −5.646686927 6.973646 6.42919 7.4423 1.661149 6.043524 4.476242 LRR1 −0.648810972 0.051560318 0.035225587 −5.687911995 6.344798 6.184248 5.389265 1.661149 4.539173 3.676349 NENF −0.619232567 0.054043498 0.039556312 −5.695895386 11.225792 11.174733 10.613794 7.748771 9.563208 8.66481 CDK2AP2 −0.655978784 0.050993826 0.034254508 −5.705594812 11.989307 9.781927 10.520155 8.270632 7.269549 8.834367 SLC41A1 −0.683629873 0.049394421 0.031323579 −5.712085204 10.073312 9.9999 11.136698 5.891233 8.181074 8.622681 TAPBP −0.670970149 0.050055202 0.032628105 −5.727261606 11.25105 10.658398 10.427581 7.792994 8.140553 9.018932 MMP19 −0.59453525 0.056882604 0.043695815 −5.736091038 8.947392 8.225386 10.315121 5.705318 6.373501 8.010706 TRIM26 −0.701262867 0.048630415 0.029732562 −5.753796151 10.681293 10.996101 11.130529 8.156778 8.36819 8.929599 ANKRD33B −0.63567357 0.05262489 0.037205172 −5.775491806 7.956174 6.821329 8.66852 5.320955 5.509998 5.426231 PARP1 −0.586053813 0.057869242 0.045358285 −5.80921866 9.11634 9.228604 7.7303 6.283686 6.551443 6.69026 SHISA5 −0.665021558 0.050400851 0.033282749 −5.819082058 11.305107 9.935252 9.494939 6.954147 8.36819 7.611911 TAF3 −0.719891668 0.047724223 0.02794556 −5.824117325 9.648253 9.162364 9.636624 5.026959 7.094585 7.611911 BCL9L −0.737998639 0.047140798 0.026553249 −5.831655264 10.484506 10.53294 10.868547 7.556937 7.989035 8.519314 PNLDC1 −0.57890274 0.058863581 0.046931609 −5.83947779 6.227577 4.736586 6.175931 1.661149 4.539173 3.630092 RHBDL1 −0.706030827 0.048351237 0.029227628 −5.85120299 4.209882 4.80797 6.056062 1.661149 2.265287 2.921909 IDO1 −0.569865599 0.06033611 0.048936373 −5.85120299 4.209882 5.789702 6.976024 1.661149 4.797798 2.921909 NEURL3 −0.685884181 0.049293152 0.031059544 −5.858441778 4.815804 6.502398 3.90836 1.661149 2.265287 2.921909 LY6K −0.596903477 0.056619804 0.043368493 −5.866673135 8.369902 9.770854 7.519866 4.718672 6.189775 7.218312 NPM3 −0.666742144 0.050336605 0.03314801 −5.868917913 10.184989 10.45438 9.569802 7.631894 6.794431 8.305171 ALG3 −0.661252638 0.050645852 0.033681524 −5.876019123 10.793848 10.601206 9.226523 8.239009 5.936219 8.232333 THAP3 −0.712652267 0.047957459 0.028498809 −5.877637703 9.301804 8.841005 8.874506 7.037879 6.319269 6.051818 DPYSL4 −0.678658873 0.049556832 0.03175706 −5.879264025 7.445608 8.136169 8.13956 4.802615 5.936219 5.580533 ATAD3A −0.590293302 0.057400709 0.044559374 −5.885294589 8.313476 8.535576 7.663508 7.037879 5.509998 5.106393 DYNLL1 −0.703486747 0.048494719 0.029511398 −5.902963212 12.686273 13.376538 14.094171 10.580119 10.815098 11.043888 SDK1 −0.588136115 0.057577292 0.044949302 −5.911469437 10.009622 7.303362 7.628916 4.739845 6.774676 5.900694 UCN2 −0.688546416 0.049115877 0.030789384 −5.918405557 4.209882 4.830496 5.596986 1.661149 2.265287 2.921909 PLCD4 −0.637201839 0.052523453 0.037047295 −5.918405557 4.815804 4.830496 5.225216 1.661149 2.265287 3.630092 SLC20A2 −0.582710102 0.058324851 0.046089146 −5.939296851 9.830202 10.999267 8.553333 7.25991 7.174648 7.988762 HES6 −0.699391995 0.048734593 0.029926506 −5.944987954 8.0045 6.849665 7.663508 5.728038 3.134528 5.091834 ASB6 −0.746577559 0.046800775 0.025879551 −5.949214733 9.186094 9.789261 9.048192 6.550689 6.613395 7.020304 ACOX3 −0.658170362 0.050826016 0.033993195 −5.984695075 7.867504 7.899144 8.366488 6.664985 5.317867 4.476242 COL4A1 −0.628216583 0.053354225 0.038369513 −5.993564323 13.2 11.517125 11.709604 8.346785 9.776594 10.616586 MVK −0.725430667 0.047551011 0.027467846 −6.022175436 8.224469 7.303362 6.450701 1.661149 4.797798 5.634184 CLSTN3 −0.582365366 0.058378104 0.046156516 −6.059257337 9.496006 7.991061 9.460924 4.739845 6.861783 7.873743 PLSCR2 −0.637718941 0.052501106 0.036964274 −6.082249516 4.815804 4.736586 6.175931 1.661149 3.571326 2.921909 MESDC1 −0.76805643 0.046157531 0.024259952 −6.120787725 8.720278 8.34965 9.093298 5.891233 6.189775 6.106561 MAMLD1 −0.653010131 0.051221132 0.03466281 −6.126074355 6.186289 6.228068 7.381261 4.739845 3.571326 4.146207 SLC16A7 −0.568540828 0.060558243 0.049260293 −6.159206453 5.753024 4.830496 5.544653 1.661149 4.539173 2.921909 RPS6KB2 −0.65630138 0.050987756 0.034214359 −6.16819254 6.099991 6.537655 4.285996 1.661149 2.265287 4.476242 PAK6 −0.597910353 0.056511538 0.043207213 −6.16819254 5.316227 7.631788 4.285996 1.661149 4.539173 2.921909 NOL7 −0.565942528 0.061013478 0.049775434 −6.16819254 6.973646 6.821329 4.285996 1.661149 3.134528 5.426231 PPP1R3F −0.645798961 0.051818705 0.035789044 −6.173852491 9.632963 8.136169 8.767255 6.067497 5.509998 7.352555 INHBA −0.743983806 0.046883977 0.026065328 −6.21077408 7.906175 7.197097 7.107458 1.661149 5.920411 4.562324 REC8 −0.654372642 0.051128995 0.03448588 −6.211188386 6.648293 7.912639 8.932392 4.013424 4.539173 6.587378 HS6ST1 −0.811798301 0.045218796 0.021255529 −6.214967094 8.224469 8.595375 9.243773 1.661149 6.608026 6.051818 SLC3A2 −0.770754927 0.04607418 0.02404015 −6.222570977 12.31447 11.868263 11.933413 9.337546 9.158864 9.676959 UBTD1 −0.708048713 0.048268527 0.029007826 −6.233207508 9.247621 9.434406 9.66678 6.252746 6.794431 7.582913 MAP3K6 −0.646038166 0.051811216 0.035749575 −6.251857735 7.067614 8.278469 9.099629 5.026959 6.205902 5.634184 C14orf176 −0.630776355 0.053145686 0.03793195 −6.260290154 3.350997 4.911517 6.601009 1.661149 2.265287 2.921909 DHX37 −0.649742472 0.051496281 0.035084042 −6.265496617 8.294165 8.988481 7.899474 5.252045 5.306419 7.03218 GFM1 −0.617366115 0.054239984 0.039863219 −6.275649048 8.84495 8.916627 7.4423 6.252746 5.857745 6.195186 REL −0.77035407 0.046076407 0.024057843 −6.288132133 11.464756 11.038265 12.534117 8.895478 8.385634 9.143346 PEX10 −0.617195855 0.054273567 0.039939435 −6.289823517 7.744853 7.615377 6.031658 4.718672 4.539173 5.091834 GFER −0.722844951 0.04762218 0.027660429 −6.316630267 9.83355 8.595375 8.925282 6.339437 5.936219 7.020304 ULK1 −0.728553698 0.047423411 0.027214699 −6.336831217 9.277427 8.603718 9.955583 4.894482 6.78473 7.291822 PLAC8L1 −0.752486578 0.046595104 0.025434502 −6.386730266 4.815804 4.750708 5.596986 1.661149 2.265287 2.921909 IRF7 −0.630020793 0.053186878 0.038070772 −6.390636271 9.227402 9.626816 9.902263 8.173604 6.551443 6.931222 E4F1 −0.778544452 0.045844227 0.023423613 −6.404922988 5.491121 4.911517 4.944468 1.661149 2.265287 2.921909 C8orf73 −0.744516681 0.046883977 0.026044913 −6.431708718 6.099991 6.139057 6.83141 1.661149 4.131418 4.146207 LEPRE1 −0.640950745 0.05213413 0.036409663 −6.453879381 5.316227 4.351315 5.389265 1.661149 2.265287 3.630092 HLX −0.573475064 0.059795609 0.048169445 −6.453879381 6.52121 4.351315 5.702912 1.661149 4.608763 2.921909 ILK −0.731855259 0.047353867 0.026993535 −6.455088136 12.117061 12.072184 12.305422 9.08528 9.426624 10.171703 PACS1 −0.767247636 0.046164489 0.024342974 −6.464290503 9.065993 8.509169 8.345336 4.739845 6.373501 6.106561 SRGAP1 −0.728915344 0.047423411 0.027194284 −6.488745223 10.166524 10.926298 11.422028 7.037879 8.724089 8.32282 ADO −0.728523362 0.047423411 0.027221504 −6.496926702 8.804578 8.147628 8.767255 6.067497 6.613395 4.562324 CCDC86 −0.808952879 0.045247607 0.021441307 −6.497686323 10.033108 11.065705 9.969475 7.607339 7.269549 7.46072 KIAA0368 −0.751219483 0.046631339 0.02552637 −6.515005865 11.299065 11.518229 12.061349 8.94532 9.357582 8.579284 GANAB −0.739027971 0.04712834 0.026464103 −6.517918164 11.422029 10.227521 9.369586 7.274575 7.713236 7.523109 SERPINB6 −0.704762756 0.048386088 0.029343995 −6.521375886 11.284461 10.414621 10.508308 7.631894 8.332658 8.579284 CHTF18 −0.666944265 0.050336605 0.033127594 −6.548513661 8.691047 9.145317 10.459924 6.664985 5.920411 7.748756 DNER −0.800027807 0.045343942 0.022031303 −6.572701764 7.278811 6.732825 6.355801 1.661149 4.131418 4.562324 MIR205HG −0.777286105 0.045858846 0.023507315 −6.605553343 9.761558 12.403193 9.272072 7.037879 7.167462 6.722123 SDS −0.690986891 0.048967655 0.03059476 −6.628983794 5.056948 4.389936 7.942366 1.661149 3.571326 2.921909 LHFPL2 −0.590604418 0.05733088 0.044475672 −6.675087649 10.509839 10.015619 10.548196 7.771052 9.357582 6.924055 CLN6 −0.753874937 0.046571395 0.025353522 −6.681745529 7.906175 8.692451 7.663508 6.063041 5.165949 4.476242 RAB14 −0.823445693 0.045005314 0.020505614 −6.688665342 12.216577 11.995784 12.002604 9.260886 9.492512 9.201749 PKM2 −0.713312871 0.047910176 0.028425995 −6.69713948 12.705129 11.923468 11.142841 9.179923 9.128102 9.547827 BOP1 −0.705631933 0.048360255 0.029260293 −6.736594165 8.107653 9.391678 8.634047 7.037879 4.797798 5.882028 FTX −0.734915262 0.047277268 0.026717931 −6.736949755 11.37685 11.502697 10.748801 8.616619 8.624754 8.745549 C1QB −0.654980874 0.051064299 0.034386526 −6.737316104 6.48761 4.413323 8.151795 1.661149 2.265287 5.580533 E2F3 −0.776480516 0.045873421 0.02360871 −6.770394439 8.254752 8.544272 8.487278 5.728038 6.237456 4.790662 WDR45 −0.851215296 0.044490827 0.018807077 −6.80048145 11.631749 11.067214 10.965312 8.301578 8.220489 8.357484 CLTB −0.787568327 0.045564387 0.022781899 −6.806256017 10.452202 11.32738 10.365897 6.550689 7.68534 8.66481 TCIRG1 −0.755218454 0.046505334 0.025243961 −6.809129204 10.956225 9.853646 10.1327 7.36523 7.187136 8.095288 MT2A −0.583221464 0.058250261 0.045942838 −6.825889039 16.589026 16.588349 15.299176 12.528159 13.23365 15.384407 FAM3A −0.732351939 0.047319258 0.02695883 −6.833413098 11.05991 10.052661 9.955583 6.811341 7.656894 8.287303 UBN1 −0.783419109 0.045695042 0.023071113 −6.835279089 8.630745 8.041069 8.063885 4.718672 5.857745 5.634184 DIO3 −0.757564004 0.046414887 0.024984008 −6.873299715 4.815804 4.750708 5.702912 1.661149 2.265287 2.921909 SLC25A38 −0.625092429 0.053581742 0.038751956 −6.884540775 9.558037 9.568332 9.283238 6.252746 6.774676 8.213534 UNC45A −0.707208261 0.048286461 0.029084042 −6.889717456 10.991122 9.807436 9.854403 8.206677 7.656894 6.69026 ATG4B −0.817377487 0.045152347 0.020873086 −6.909282283 10.228873 9.778245 10.284887 4.894482 7.440337 7.774634 MYLPF −0.691757806 0.048955004 0.030545083 −6.910284693 5.304463 6.044198 4.449894 1.661149 2.265287 3.630092 ANKMY1 −0.674662752 0.04983446 0.03220211 −6.910284693 6.898923 5.195784 4.449894 1.661149 3.571326 2.921909 FBXO18 −0.702920534 0.048515004 0.0295672 −6.912562631 11.784865 10.539479 10.239746 7.450526 8.181074 8.822008 LTBP3 −0.725943931 0.047543032 0.027439946 −6.915055221 9.799716 10.815719 11.383636 6.252746 8.2398 8.593895 NRXN2 −0.570411423 0.060316154 0.048837019 −6.931329527 4.682076 4.750708 7.401896 1.661149 4.608763 2.921909 ADCK5 −0.740465724 0.047053425 0.026338891 −6.933443315 8.5104 7.402335 7.794136 4.894482 4.608763 5.900694 CYP1A1 −0.795787918 0.045395954 0.022293297 −6.941746079 7.513971 6.792427 6.601009 4.718672 4.131418 2.921909 SCT −0.609808088 0.055104214 0.04098673 −6.972580711 3.350997 5.148082 5.723602 1.661149 2.265287 2.921909 ZNF703 −0.69264847 0.048944238 0.030441647 −6.984324236 5.658609 7.197097 7.899474 5.095353 4.131418 2.921909 CLCF1 −0.746989541 0.046798828 0.025848248 −6.998171017 7.579241 8.329668 8.743197 5.728038 5.936219 4.476242 CRTC2 −0.806427756 0.045297753 0.021613474 −7.006635641 9.358681 8.868964 9.7854 6.550689 6.549959 6.455366 AGPAT6 −0.841889051 0.044695604 0.019338551 −7.010405138 10.52234 10.346648 10.309671 7.792994 7.53715 7.291822 KRT5 −0.772872808 0.046036363 0.023862538 −7.016388947 12.45478 15.685283 11.439601 8.628872 10.167971 10.106959 FAM131A −0.654351102 0.051134477 0.034501531 −7.017626845 8.668728 7.34377 6.175931 4.013424 5.857745 4.146207 FAM50B −0.779463329 0.045829476 0.023342634 −7.020345328 6.973646 6.957749 6.489771 1.661149 4.797798 4.146207 SEC16A −0.814901589 0.045198955 0.021101735 −7.056830439 10.412457 10.760815 9.996864 7.177844 7.627877 7.774634 NUDT4 −0.588394916 0.057530341 0.044885335 −7.070634371 12.289089 11.431828 10.190185 7.243046 8.609988 10.413286 NFYA −0.774681697 0.046000938 0.02378428 −7.074457873 10.226328 9.511817 10.295954 7.037879 7.473335 7.36177 GABBR1 −0.726034179 0.047543032 0.027433141 −7.099804308 10.432466 9.781927 10.559721 6.954147 8.296229 7.492252 MGC12982 −0.663891751 0.050428178 0.0333508 −7.109836982 6.648293 4.389936 6.976024 1.661149 3.571326 4.146207 HLA-C −0.777917909 0.045844227 0.023450834 −7.109901294 14.565223 14.24246 14.570289 11.412631 12.186026 11.653272 SRGAP2 −0.734434678 0.047307334 0.026759442 −7.116280157 9.806546 8.509169 10.336718 5.743334 7.505595 6.649696 MIR3682 −0.722993726 0.04762218 0.027646819 −7.117449004 6.820119 7.679931 8.279951 5.448591 5.165949 3.630092 GPR137 −0.825702351 0.044949653 0.020389929 −7.121901626 10.454378 9.898421 9.816476 5.705318 7.066159 7.800057 C1orf216 −0.789983711 0.045525452 0.022658727 −7.128194378 7.716122 7.26179 7.4423 5.448591 4.608763 2.921909 DUSP4 −0.69228366 0.048955004 0.030479755 −7.129613805 10.403474 13.158825 11.763423 9.584013 8.277663 8.929599 KAZN −0.713190736 0.047910176 0.0284328 −7.133128022 10.52855 10.664394 9.696318 8.628872 6.861783 7.152205 ABCA2 −0.669642476 0.050087347 0.032736985 −7.140756662 7.730559 8.436292 9.490128 4.894482 6.373501 6.455366 NUDT22 −0.622993791 0.053781042 0.039014631 −7.141197354 7.641685 6.466258 5.018694 1.661149 5.353925 3.630092 SLC26A6 −0.615844857 0.054404356 0.040095951 −7.163505134 8.69841 6.821329 9.255159 5.705318 5.857745 5.882028 IP6K1 −0.789213913 0.045529634 0.022683226 −7.170773077 9.3863 9.520657 10.036997 6.544171 7.107836 7.020304 METTL1 −0.674088929 0.049888566 0.032291256 −7.179599117 7.686806 7.383076 5.723602 1.661149 4.539173 5.446557 HIPK2 −0.722346377 0.047646206 0.027699217 −7.192137635 11.585835 10.428779 9.310781 7.582358 7.56803 7.748756 SCFD2 −0.807485972 0.045272487 0.021529772 −7.193247514 6.417969 6.044198 6.601009 1.661149 3.571326 4.146207 NT5DC3 −0.647772701 0.051631895 0.035416128 −7.195500884 9.170294 11.432999 10.640089 7.792994 8.140553 7.722406 PARP16 −0.795899369 0.045374706 0.022268118 −7.226627157 6.417969 6.03611 7.462086 1.661149 4.608763 3.630092 DHX38 −0.601623285 0.056111267 0.042501531 −7.241003583 10.518185 8.561508 10.730562 5.705318 7.440337 8.79697 RRAGA −0.77195692 0.046057921 0.023937394 −7.242751562 12.257657 11.356063 11.196982 7.856887 9.401119 8.784285 THPO −0.797000919 0.045366463 0.022191902 −7.247685686 5.779429 5.43468 6.072169 1.661149 3.571326 2.921909 CD101 −0.637988809 0.052496924 0.036928887 −7.262730803 5.744513 8.181467 8.458015 5.320955 2.265287 5.900694 VANGL2 −0.708447426 0.04824159 0.028925485 −7.266727449 7.445608 6.537655 8.54408 4.802615 5.509998 3.676349 PWWP2B −0.643105923 0.05194815 0.036157877 −7.276084409 6.846868 7.402335 7.855267 6.396698 4.539173 2.921909 DNAJC8 −0.848420041 0.044599879 0.019015311 −7.296850735 11.66877 11.352354 11.224758 8.688623 8.564762 8.357484 ITFG3 −0.637419733 0.052514975 0.037019394 −7.302072329 9.902119 8.407985 7.7303 4.718672 6.319269 7.033813 NONO −0.783818675 0.045695042 0.023057503 −7.305648867 11.935794 12.567904 11.872799 9.698891 9.451686 8.834367 TUBB4B −0.67555335 0.049794345 0.032143586 −7.310908571 13.313745 14.69107 14.743622 11.849546 11.567822 11.821019 RAB33A −0.701754769 0.048571998 0.029671997 −7.351296306 6.554045 5.362142 6.012527 1.661149 3.134528 4.476242 NASP −0.833088605 0.044797567 0.019829874 −7.353070822 11.753395 11.774369 12.393714 8.875048 8.951948 9.372483 SV2A −0.708764122 0.04824159 0.02890507 −7.372390938 9.689484 7.679931 6.601009 5.743334 4.797798 4.476242 ZSCAN16 −0.622379472 0.053792728 0.039134399 −7.375779037 6.417969 5.148082 4.724406 1.661149 2.265287 4.476242 TIPRL −0.82755683 0.044930476 0.020250425 −7.400189864 10.078965 9.168002 9.149294 6.396698 7.191402 5.091834 TRIP4 −0.788658035 0.045550411 0.022728819 −7.400521501 9.206896 8.278469 7.360327 1.661149 6.319269 5.580533 CALCA −0.775356807 0.045942803 0.023724396 −7.40085677 4.743564 5.809601 4.944468 1.661149 2.265287 2.921909 C15orf48 −0.58770507 0.057633938 0.045025519 −7.406055343 7.980539 8.660813 8.366488 7.504712 5.317867 5.091834 LAMB2 −0.777110997 0.045858868 0.023531814 −7.424694627 12.063179 12.135419 12.701612 9.049264 9.809281 9.769968 ZNF395 −0.650032917 0.05147219 0.035035046 −7.455800752 12.222335 10.405104 10.234003 7.33564 8.696398 8.952456 PPP2CB −0.814928785 0.045198955 0.02109493 −7.458084416 13.268699 13.616544 14.099313 10.369894 10.769315 11.146572 PRDX6 −0.82578989 0.044949653 0.020369513 −7.494335789 14.518145 13.702332 14.113068 10.873216 11.207267 11.512316 ASCC1 −0.765379888 0.046178907 0.024447091 −7.523695748 10.098578 7.843866 8.702188 1.661149 7.187136 6.195186 MTHFD2L −0.664716652 0.050400851 0.033296359 −7.570034815 6.054828 7.129367 5.389265 1.661149 3.134528 5.106393 POU3F1 −0.626828337 0.053474985 0.038534195 −7.570034815 6.054828 6.311907 8.525393 4.718672 3.134528 5.106393 S100A9 −0.625688072 0.053562842 0.038714529 −7.570034815 6.054828 8.628465 5.389265 1.661149 3.134528 6.129407 IL23A −0.639514586 0.052338861 0.036643756 −7.575844619 7.067614 5.195784 7.180931 4.894482 2.265287 4.146207 PCMT1 −0.831868027 0.044860922 0.019922423 −7.582887957 12.028542 11.73977 11.504251 9.260886 8.817023 8.424409 SH3PXD2A −0.784249598 0.045655746 0.023012589 −7.585348973 10.671972 10.20576 11.2175 7.037879 8.502167 7.748756 WFIKKN1 −0.706615224 0.048309794 0.029140524 −7.623729122 3.839948 5.195784 6.410545 1.661149 2.265287 2.921909 SLED1 −0.637627755 0.052501106 0.036977884 −7.623729122 5.263699 5.195784 7.762571 4.718672 2.265287 2.921909 IRX1 −0.830498767 0.044867325 0.020039469 −7.627233895 8.85157 11.519332 8.011136 6.283686 5.920411 5.426231 ELF4 −0.905277707 0.044173537 0.016165362 −7.63546089 8.028068 7.912639 8.024505 5.095353 4.131418 5.091834 HMGA1 −0.729910375 0.047394039 0.027116026 −7.657934818 10.577293 12.256783 10.644425 9.154721 8.055928 7.640338 AGPAT2 −0.778899498 0.045829476 0.023376659 −7.716391719 9.077334 8.92996 7.680498 5.320955 5.509998 6.129407 MVP −0.789558511 0.045529634 0.022669616 −7.740124088 10.620572 9.396488 9.028421 1.661149 7.31791 7.668215 JMJD8 −0.694843851 0.048858998 0.030273562 −7.747993073 10.655041 10.381035 9.504512 6.550689 7.191402 8.60836 FAM189B −0.849137033 0.044539625 0.01893297 −7.751345264 8.890666 8.147628 7.997641 1.661149 5.936219 5.634184 SNORD22 −0.890373718 0.044203301 0.016971759 −7.759185469 8.051258 8.889584 8.26876 5.095353 5.317867 5.446557 RASSF4 −0.762876577 0.046294386 0.024682545 −7.763926618 10.056219 9.201373 10.282106 6.244586 6.640994 7.897492 HNRNPU −0.840983962 0.044701668 0.01941953 −7.766460499 12.975954 13.437325 13.701247 10.74399 10.511716 9.851274 OSTF1 −0.844187678 0.044645837 0.019204491 −7.811794785 11.017855 10.055705 11.088182 8.122528 7.56803 7.218312 UBL4A −0.730641943 0.047384624 0.02706703 −7.814991529 9.750974 8.445606 8.428147 5.320955 6.78473 6.106561 RNASEH1 −0.759292758 0.046382879 0.024892821 −7.835235608 8.84495 6.983552 7.056312 1.661149 4.797798 5.874974 WWTR1 −0.712205346 0.047984994 0.02855393 −7.856603559 10.914153 12.234791 13.174964 9.260886 9.64516 9.072081 SLC23A3 −0.632169178 0.05307838 0.037804695 −7.880354138 4.639409 6.049721 8.102218 1.661149 4.797798 3.630092 PORCN −0.724044292 0.047585406 0.027537258 −7.902791099 7.773024 5.297868 6.056062 1.661149 3.134528 4.790662 RC3H2 −0.773677971 0.046006594 0.023815584 −7.917186749 8.713026 8.158996 8.735088 5.728038 5.165949 6.32627 SSR2 −0.80736439 0.045278798 0.02154066 −7.936730826 12.676518 11.783579 11.727086 9.002943 9.687973 8.60836 SLC25A37 −0.797680187 0.045355733 0.022136781 −7.969225848 9.625257 11.312186 9.948587 6.954147 6.78473 7.920856 HCCS −0.84804937 0.044599879 0.019022116 −7.972366897 9.648253 9.184784 8.607641 6.067497 6.189775 6.195186 BLOC1S1 −0.763008009 0.04628868 0.024658047 −7.997576706 11.610439 10.845928 10.242609 7.243046 7.31791 9.092804 PPIF −0.780944698 0.045805247 0.02328411 −8.023150935 11.643242 12.044868 11.755426 9.81605 8.751258 8.11568 PDLIM7 −0.806679401 0.045297753 0.021599864 −8.033212252 11.459349 11.804542 11.210206 7.42265 8.453372 9.363984 LAT −0.783124361 0.045695042 0.023091528 −8.124475148 9.21205 8.841005 10.39192 6.183122 6.189775 7.152205 GLS −0.738297443 0.047140798 0.026532834 −8.128310697 9.936777 10.794007 11.830609 7.771052 8.724089 7.428484 PLOD3 −0.840077898 0.044722631 0.0194869 −8.155236142 10.163866 10.135563 9.400679 5.026959 7.107836 7.428484 GPC1 −0.663765178 0.050437995 0.033373256 −8.17454591 9.09418 10.046553 7.227914 6.063041 5.317867 6.722123 GMPS −0.764905926 0.046181862 0.024505614 −8.174607461 9.105302 9.081032 7.593473 6.550689 5.509998 4.562324 RABL3 −0.755134568 0.046508764 0.025254849 −8.220449372 10.587244 9.96146 8.767255 5.728038 7.25505 7.327219 ECM1 −0.860989871 0.044379352 0.018367472 −8.247641658 10.869187 10.23291 10.484319 5.252045 7.440337 8.213534 SLC18A2 −0.844741392 0.044645837 0.019197686 −8.260502478 6.617556 7.383076 6.175931 1.661149 3.571326 4.476242 LRRC20 −0.579815073 0.05881361 0.046789384 −8.280514429 4.815804 6.184248 7.462086 1.661149 3.134528 5.634184 DGKD −0.905722119 0.044173537 0.016124532 −8.296655574 8.36065 9.778245 8.562528 5.743334 5.509998 5.446557 SNHG15 −0.84533808 0.044645837 0.019170466 −8.308653721 11.183126 11.461972 11.350843 6.651882 8.296229 9.051056 IL1RL1 −0.866653723 0.044377262 0.018072133 −8.324540446 12.185473 12.502474 11.753421 8.122528 9.128102 9.555312 FCER1G −0.654102238 0.051134477 0.034508336 −8.345884991 5.982974 3.360637 5.596986 1.661149 2.265287 2.921909 TUBGCP2 −0.682996378 0.049394421 0.031361688 −8.356548197 10.748456 9.332664 8.642743 5.579836 7.56803 7.180104 SP9 −0.787330732 0.045564387 0.022795509 −8.358472793 5.328526 4.351315 6.489771 1.661149 2.265287 2.921909 PPAP2B −0.806277462 0.045315307 0.021630487 −8.421171228 14.571377 12.857663 12.843677 6.252746 11.497356 10.565606 ARHGAP39 −0.852380327 0.044480228 0.018746512 −8.428829214 5.491121 5.340619 5.225216 1.661149 2.265287 2.921909 ZFAT −0.682791216 0.049399307 0.031383464 −8.429446045 6.306772 4.736586 6.054038 1.661149 4.131418 2.921909 NPTX2 −0.673185212 0.0499291 0.032349098 −8.429446045 8.763044 4.736586 7.056312 1.661149 2.265287 6.32627 UBE3C −0.774376467 0.046000938 0.023791085 −8.447539069 10.898254 11.067214 9.757647 5.891233 7.819723 8.472642 LRCH1 −0.799924524 0.045343942 0.022051718 −8.480062502 10.832846 10.868609 11.67399 7.748771 8.4199 8.564524 TUBBP5 −0.747515272 0.046789913 0.025821708 −8.531355643 7.701538 8.319573 7.519866 2.820813 4.608763 6.455366 KCNQ4 −0.680923186 0.049467746 0.031565839 −8.53297923 6.227577 6.792427 5.609945 1.661149 3.134528 5.091834 STK39 −0.82388972 0.044990161 0.020477033 −8.556950093 8.720278 9.679079 8.418052 5.320955 5.920411 6.385515 GRID1 −0.839057005 0.044732882 0.01956788 −8.574123645 10.497228 8.805276 9.167487 6.067497 3.571326 7.523109 APEH −0.754272665 0.04655221 0.025321538 −8.593488103 11.115975 10.638232 9.653933 6.550689 7.440337 8.503924 MAP2K1 −0.911252149 0.044159136 0.015817625 −8.595705298 12.344701 11.573437 12.291665 8.579223 8.469821 9.329475 NRM −0.850189273 0.044510429 0.018871725 −8.60178564 7.701538 6.270596 7.250844 1.661149 4.608763 4.146207 FADS3 −0.862559101 0.044377262 0.018266757 −8.648292961 11.06988 10.208498 10.91953 7.957464 6.78473 7.897492 BAK1 −0.739431397 0.047109709 0.026415788 −8.650726573 7.259029 8.473191 6.948237 6.067497 3.134528 4.146207 UBE2J1 −0.775954349 0.045911642 0.023673358 −8.663216582 12.155021 11.116154 11.028054 9.040118 7.767462 8.745549 PDGFRB −0.721682286 0.047677157 0.027789724 −8.672663054 12.834827 10.887527 12.05077 7.771052 9.673843 9.532738 SQSTM1 −0.922359369 0.044110923 0.015241239 −8.686796628 13.688951 13.715385 13.806091 10.541751 10.596561 10.853609 GLG1 −0.790337992 0.045525452 0.022645117 −8.689426722 12.528932 11.153577 11.93164 7.792994 9.409671 9.220702 ZNF496 −0.853409752 0.044464174 0.018670296 −8.704706925 7.730559 7.512784 7.997641 1.661149 4.608763 5.634184 FAM171B −0.827327042 0.044930476 0.02027084 −8.707682082 4.639409 6.044198 7.227914 1.661149 3.134528 2.921909 MTHFR −0.828775193 0.044930476 0.020208234 −8.715420287 11.183126 10.393119 11.824889 7.504712 7.269549 8.941073 LRWD1 −0.808112394 0.045257569 0.021501191 −8.723384602 7.956174 7.664061 7.204614 5.448591 4.539173 3.630092 THTPA −0.759874813 0.046382879 0.024865601 −8.741084651 7.410173 6.049721 6.891005 4.894482 3.571326 2.921909 PACSIN3 −0.682045731 0.049418096 0.031470568 −8.767275637 6.417969 6.762934 6.054038 5.095353 3.134528 2.921909 ZDHHC9 −0.757708199 0.046414887 0.024977203 −8.776888283 11.202676 10.7664 10.207872 7.074163 7.187136 9.008063 CHPF −0.760658727 0.046345577 0.024812521 −8.795458469 10.744904 9.634981 8.418052 6.498222 7.174648 6.051818 IRF5 −0.8939899 0.044203301 0.016815243 −8.802834196 9.037244 9.019996 8.775186 6.244586 5.165949 5.882028 REEP4 −0.816551838 0.045165524 0.020930929 −8.832840053 8.804578 8.723411 8.063885 4.718672 6.189775 5.580533 CBLL1 −0.918716606 0.044110923 0.015376659 −8.856956289 9.349356 9.190335 8.903739 6.283686 6.043524 5.426231 AGER −0.588970503 0.05748724 0.044788023 −8.857020985 6.344798 4.80797 5.596986 1.661149 2.265287 5.091834 TARBP2 −0.721147201 0.047696784 0.027823069 −8.881028124 7.278811 6.072636 6.072169 1.661149 5.353925 2.921909 SDR39U1 −0.755368897 0.046505334 0.02521674 −8.890527039 12.032189 11.748263 12.248164 8.173604 8.87992 10.242966 ACVR1B −0.826772934 0.044930476 0.020304866 −8.922320379 9.562079 9.352605 9.749619 7.25991 6.319269 6.195186 YKT6 −0.894968224 0.044203301 0.016774413 −8.973397163 10.626374 10.238279 9.671037 5.095353 7.174648 7.46072 CHPF2 −0.62615087 0.053522686 0.038666894 −8.996682069 6.58615 5.43468 2.995681 1.661149 2.265287 2.921909 RBM19 −0.886272888 0.044203301 0.0171623 −9.028585084 9.949176 10.339172 9.431116 7.109557 6.774676 6.32627 C13orf33 −0.865605462 0.044377262 0.018106159 −9.041434449 9.740312 8.595375 8.88187 5.705318 6.794431 4.146207 PVT1 −0.822965869 0.045019115 0.020555291 −9.08210941 9.789409 12.918293 10.823365 8.501391 6.861783 7.640338 YARS −0.780860706 0.045805247 0.023290915 −9.105581266 10.373887 10.484061 9.226523 7.210813 7.187136 7.180104 GPN2 −0.663820017 0.050437995 0.033366451 −9.136954894 6.52121 6.391145 6.012527 2.820813 3.134528 5.091834 PTMS −0.930005374 0.044037172 0.014813882 −9.159799465 12.719677 12.547504 12.836114 8.331873 9.524361 9.899123 DAAM2 −0.875988795 0.044285705 0.017627765 −9.192810828 10.673841 10.484061 11.337515 1.661149 7.473335 8.974957 HLA-B −0.902314281 0.044190907 0.016344335 −9.25062158 16.466846 16.263629 15.995935 13.054079 12.325882 13.564862 WDR43 −0.800144549 0.045343942 0.021997278 −9.259256622 10.647452 11.766958 11.199931 7.243046 7.989035 9.113234 PATH −0.887419322 0.044203301 0.01713508 −9.278797097 11.115975 9.931942 11.267554 6.954147 7.292524 8.053616 KLC1 −0.930230507 0.044025007 0.014791426 −9.294454255 12.648279 12.464036 11.669742 8.65307 8.453372 9.462817 PTRH1 −0.752206336 0.0466011 0.025467846 −9.295542761 9.61362 9.710324 7.956385 4.739845 5.857745 7.291822 HBA2 −0.951403686 0.043900827 0.01383804 −9.30742812 10.755533 10.889234 10.414946 1.661149 7.53715 7.873743 MFSD5 −0.917671402 0.044110923 0.015435182 −9.311913641 9.262601 8.595375 8.076776 1.661149 6.043524 5.446557 EXOC3L4 −0.841331228 0.044701668 0.01939231 −9.333292622 4.682076 5.487673 6.355801 1.661149 2.265287 2.921909 WDR5 −0.763520152 0.046268297 0.024624702 −9.34318169 7.355332 7.476899 6.450701 1.661149 4.131418 5.446557 APEX2 −0.835171682 0.044793607 0.019708744 −9.34402914 8.804578 8.359538 6.800663 1.661149 5.165949 5.580533 LOX −0.804037633 0.045334912 0.021789044 −9.352297424 10.412457 9.737119 8.279951 5.448591 7.187136 6.051818 ABHD2 −0.776144043 0.045884853 0.023644097 −9.386078011 10.334258 10.009352 8.257481 5.026959 7.174648 6.73963 SOLH −0.885595922 0.044203301 0.01720313 −9.446624761 9.121827 9.20686 9.015087 6.550689 5.509998 5.882028 CORO1B −0.711158742 0.048057698 0.028658047 −9.447026393 10.822774 9.239354 8.313014 4.718672 6.78473 7.582913 NHEJ1 −0.834626565 0.044793607 0.01972916 −9.465030148 9.26756 9.13384 9.008374 5.891233 5.317867 6.924055 PRR7 −0.749289358 0.046728791 0.025706022 −9.499912701 6.924263 7.282726 6.175931 1.661149 5.306419 3.676349 FAU −0.808739538 0.045247607 0.021454917 −9.51088753 15.808595 16.338149 15.781741 12.468898 12.559015 13.877468 WBSCR16 −0.709993708 0.048157645 0.028777816 −9.556497976 8.890666 8.016282 6.072169 1.661149 5.509998 5.634184 PDPK1 −0.65781501 0.050866557 0.034060565 −9.560892278 8.705736 8.016282 8.726933 5.448591 4.608763 7.352555 BAG6 −0.914120641 0.044110923 0.015646138 −9.585705604 12.922328 12.448485 11.900255 8.768324 8.63937 9.750536 KIAA1984 −0.888800286 0.044203301 0.017060225 −9.595375997 5.316227 6.184248 5.225216 1.661149 2.265287 2.921909 ESYT1 −0.833671381 0.044797567 0.019782239 −9.65572573 11.026657 10.251615 9.769607 6.498222 7.627877 7.553321 PLEKHM2 −0.627767824 0.053380879 0.038412385 −9.683590785 6.846868 7.0089 5.225216 1.661149 3.571326 5.446557 CHI3L1 −0.83173581 0.044860922 0.019942838 −9.68778531 8.959701 9.471353 7.593473 5.743334 3.571326 6.195186 MEF2D −0.796487819 0.045374706 0.022220483 −9.709688414 10.392166 10.091744 11.958009 6.498222 7.505595 8.678584 MRPL32 −0.953418697 0.043857532 0.01374277 −9.737647816 11.704864 12.282348 12.007662 8.65307 8.724089 8.870819 FOXK1 −0.97296996 0.043681142 0.012845185 −9.770371508 9.605809 9.901809 10.295954 6.395481 6.613395 6.722123 METTL11A −0.961775474 0.043778104 0.013303164 −9.825423702 10.256573 9.725696 9.725263 6.960054 6.608026 5.091834 IL1B −0.614720956 0.054543342 0.040247023 −9.886624606 9.048812 6.702075 10.587011 5.743334 5.317867 7.03218 LOC440896 −0.578268742 0.05899939 0.047070432 −9.891289606 8.085359 6.228068 5.609945 1.661149 6.774676 2.921909 FAM70B −0.844849088 0.044645837 0.019190881 −9.892338198 6.417969 5.487673 5.571599 1.661149 2.265287 3.676349 TRMT61A −0.776150303 0.045884853 0.023637292 −9.892338198 6.48761 6.605686 5.571599 4.341916 2.265287 2.921909 SEC22B −0.783741595 0.045695042 0.023064308 −9.921385699 9.895728 9.038579 8.598731 5.728038 7.31791 5.106393 CARS −0.850201162 0.044510429 0.01886492 −9.954512035 11.776192 11.765099 10.023743 8.460842 7.713236 7.492252 SDC1 −0.745878107 0.04683654 0.02598707 −9.962353829 8.763044 12.05022 8.974332 7.210813 7.191402 5.446557 TIE1 −0.729749424 0.047394039 0.027129636 −10.0080276 9.525286 8.454859 8.677011 1.661149 5.353925 8.305171 MESTIT1 −0.814204241 0.045212649 0.021151412 −10.01085039 8.77005 8.158996 9.310781 4.718672 6.613395 5.446557 TXNRD1 −0.792345407 0.045455125 0.022502212 −10.03149741 9.927407 10.594942 9.934491 8.206677 6.608026 6.587378 RGPD1 −0.776814587 0.045858868 0.023565839 −10.03659603 7.530567 7.458616 7.082111 1.661149 4.131418 5.882028 NCKAP5L −0.939611467 0.043955231 0.014399456 −10.03834923 8.583805 8.776041 9.765631 5.448591 5.306419 6.051818 SBF1P1 −0.906556652 0.044173537 0.016076897 −10.09698092 9.541754 9.789261 9.179489 4.013424 6.205902 7.020304 GLRA4 −0.806007175 0.045315307 0.021650902 −10.15879849 5.744513 5.43468 5.609945 1.661149 2.265287 3.630092 MPHOSPH10 −0.787656452 0.045562713 0.022771011 −10.1703371 9.967577 9.964703 9.197307 5.728038 7.68534 6.618407 H2AFZ −0.946587478 0.043900827 0.014076216 −10.18956731 13.044008 14.116738 14.556262 9.739011 9.694987 11.2096 NECAP2 −0.845935978 0.044641179 0.019139163 −10.20795393 9.426762 9.291936 8.458015 5.448591 6.861783 5.106393 SH3RF2 −0.879658918 0.044278935 0.017442668 −10.2499531 5.335413 6.638536 5.018694 1.661149 2.265287 2.921909 ERMP1 −0.678869851 0.049555317 0.031746172 −10.2499531 6.52121 6.537655 5.018694 1.661149 4.797798 2.921909 MRPL41 −0.888129066 0.044203301 0.01712147 −10.32240169 11.054181 10.790357 10.000252 7.42265 7.292524 7.640338 TNFAIP2 −0.83178287 0.044860922 0.019936033 −10.37206772 12.492332 13.015697 12.411632 8.723321 9.1177 10.554443 DCPS −0.733749154 0.047307334 0.026802314 −10.41928433 8.476537 8.028729 6.056062 5.095353 4.131418 4.476242 NHLH1 −0.811631155 0.045218796 0.021275944 −10.50731094 5.658609 6.184248 5.225216 1.661149 2.265287 3.676349 RNH1 −0.984476281 0.043626235 0.012388568 −10.50807554 13.619617 12.861582 12.27568 8.993498 9.468155 9.509806 OTUD4 −0.928997003 0.044037172 0.014868323 −10.51136662 11.536357 12.264698 12.727901 9.137671 8.36819 8.870819 STX1A −0.775790664 0.045911642 0.023686968 −10.56476017 7.177073 8.586982 8.428147 5.026959 3.134528 6.195186 TTLL4 −0.955232088 0.043840967 0.013682205 −10.57578211 9.60972 9.967938 9.277666 5.891233 6.794431 5.874974 NOC4L −0.920139133 0.044110923 0.015329023 −10.62443854 11.041209 11.273484 10.117184 7.631894 6.861783 7.774634 SMG5 −0.841578697 0.044701668 0.01936509 −10.68664256 9.72957 9.655192 8.607641 6.960054 6.237456 4.790662 POLG −0.916955677 0.044110923 0.015482817 −10.70025486 11.800648 11.730275 12.326489 8.270632 8.181074 9.220702 CNPPD1 −0.886024718 0.044203301 0.01717591 −10.71327407 10.518185 9.357547 8.702188 5.705318 5.936219 6.722123 CFP −0.894698365 0.044203301 0.016794828 −10.77736692 7.906175 7.34377 7.98402 5.320955 2.265287 4.476242 CREB3 −0.941686039 0.043921714 0.014313032 −10.82470977 10.126141 9.891622 9.214907 5.579836 6.794431 6.455366 KLHL36 −0.626279448 0.053518816 0.038647159 −10.82921574 7.867504 8.417483 8.234655 4.341916 4.797798 7.46072 B3GAT1 −0.767738053 0.04616149 0.024291256 −10.8349816 4.309025 7.648015 5.702912 1.661149 2.265287 3.676349 APOA1 −0.784387536 0.045655746 0.023005784 −10.90763179 5.316227 7.174872 7.593473 1.661149 4.131418 4.146207 LAMA4 −1.011960811 0.043581008 0.011382103 −10.9413837 13.510376 13.124805 13.51518 7.771052 10.063457 10.18624 TMEM39B −0.830478048 0.044867325 0.020046274 −10.95872455 8.016332 8.417483 8.448127 4.718672 6.205902 4.562324 HIVEP2 −0.924168713 0.044091888 0.015157537 −10.9829661 10.36466 11.113235 11.47655 7.656039 7.942653 7.395512 C11or53 −0.765235387 0.046178907 0.024460701 −10.99148689 6.48761 5.195784 5.723602 1.661149 2.265287 4.146207 PEX16 −0.830671139 0.044867325 0.020025859 −11.02186796 9.964527 9.190335 8.024505 5.728038 5.317867 6.455366 MLEC −0.958245591 0.043826549 0.013490303 −11.02727643 11.173911 10.828234 11.662277 7.36523 8.098861 7.96648 VPS72 −0.881873883 0.044229452 0.017358966 −11.04290522 10.497228 10.319043 8.88187 6.252746 6.373501 7.03218 MRPS2 −0.708909556 0.04824159 0.02889146 −11.08292067 10.244048 10.578102 7.746525 6.283686 7.107836 6.32627 TEX264 −0.915798329 0.044110923 0.015550868 −11.10719774 10.563246 9.663198 10.007003 6.339437 6.189775 7.492252 PSMB2 −0.859115966 0.044387761 0.018434842 −11.13131989 12.837747 12.609931 11.330804 8.864724 9.218487 9.133378 CTRC −0.973826011 0.043681142 0.01279755 −11.15196238 5.744513 6.092406 5.592916 1.661149 2.265287 2.921909 VNN3 −0.794936082 0.045408694 0.022349098 −11.15196238 5.744513 7.547799 3.90836 1.661149 2.265287 2.921909 TIGD5 −0.955258347 0.043840967 0.0136754 −11.20119398 6.52121 7.631788 6.83141 1.661149 3.571326 4.146207 RHCG −0.742293667 0.046946487 0.02617625 −11.21170539 6.48761 5.148082 6.056062 1.661149 2.265287 4.476242 WDR90 −0.97787971 0.043661316 0.012612453 −11.21795033 5.753024 6.139057 5.596986 1.661149 2.265287 2.921909 SLC9B2 −0.907141942 0.044173537 0.016042872 −11.21838093 8.502009 7.829709 7.762571 4.341916 3.571326 5.634184 RPS6KA4 −1.001066401 0.043588662 0.011816945 −11.22400596 9.725971 9.996735 9.485302 1.661149 6.237456 6.73963 EFNB1 −0.899550073 0.044203301 0.016528071 −11.23199169 10.929879 9.921968 10.228237 6.396698 7.440337 7.327219 SHARPIN −0.959934812 0.043802358 0.013413406 −11.26016638 10.929879 10.440472 9.560654 6.067497 6.373501 7.492252 JHDM1D −0.987147795 0.043626235 0.012293297 −11.33344954 10.864285 10.082818 10.365897 6.814118 6.640994 7.36177 ST3GAL1 −0.942353766 0.043921714 0.014279006 −11.33870594 11.410866 11.971811 12.651867 7.531061 9.148683 8.549611 PKP4 −1.0455639 0.043577906 0.010153794 −11.35789927 11.427578 12.620763 11.341526 7.835902 8.077554 8.03232 FAM100A −0.983202613 0.043626235 0.012463423 −11.37073219 9.621388 10.115279 10.7688 6.339437 6.608026 6.931222 CPNE2 −0.91400021 0.044110923 0.015652943 −11.39931261 11.103549 10.91293 10.770785 7.25991 7.292524 8.357484 POLR3D −0.811536249 0.045218796 0.021282749 −11.42515884 5.779429 5.195784 6.072169 1.661149 2.265287 3.676349 RGMA −0.841203105 0.044701668 0.019399115 −11.45484611 9.399914 8.25747 9.532856 1.661149 7.174648 5.882028 LOC400043 −1.033653913 0.043577906 0.010439605 −11.45666243 10.126141 9.748452 10.151102 5.891233 6.608026 6.649696 HOXC8 −0.70977819 0.04819475 0.028815243 −11.47229801 10.213536 6.931478 9.839352 1.661149 6.319269 7.668215 LCLAT1 −0.645177416 0.051833045 0.035868663 −11.52553162 9.988753 7.857885 7.156853 6.339437 6.373501 3.630092 CAPG −1.033301159 0.043577906 0.010453215 −11.54875532 10.213536 10.073837 10.414946 6.544171 6.551443 7.020304 HSPB7 −0.960209952 0.043802358 0.013386186 −11.58860705 6.344798 5.195784 6.054038 1.661149 2.265287 2.921909 LAMC3 −0.810884673 0.045237293 0.021322218 −11.60409971 10.701589 11.225629 12.489019 5.891233 8.928336 8.952456 DAZAP2 −0.920197693 0.044110923 0.015315413 −11.60999858 13.870218 13.016869 12.862876 10.332922 10.074256 9.02972 MRPL14 −0.998615009 0.043626235 0.011890439 −11.62363013 11.550668 12.016244 11.252009 8.514658 8.011679 7.553321 TWIST2 −0.93949615 0.043986717 0.014424634 −11.66661578 4.963444 5.809601 7.575421 1.661149 2.265287 2.921909 ANKRD34C −0.93393653 0.044025007 0.01463491 −11.66689528 5.263699 6.466258 5.596986 1.661149 2.265287 2.921909 TPRN −0.682445718 0.04941326 0.031430419 −11.66689528 7.259029 6.466258 6.072169 1.661149 5.920411 2.921909 TCEB3 −1.014566892 0.043581008 0.011286832 −11.68174688 10.595155 11.365907 10.914153 7.42265 7.819723 5.874974 TRIM29 −0.677666219 0.04967045 0.031907452 −11.68820206 7.177073 9.367381 5.592916 1.661149 6.608026 3.630092 CASKIN1 −0.923579765 0.044091888 0.015184757 −11.72147892 8.947392 8.25747 7.69729 5.095353 5.306419 4.146207 GPAT2 −0.867718749 0.044335719 0.018004083 −11.76530593 8.397309 6.638536 5.217616 1.661149 3.571326 3.676349 DCTPP1 −0.959389468 0.043826549 0.013435863 −11.77479945 9.138164 9.291936 8.967426 1.661149 6.551443 5.580533 TNRC18 −0.873660024 0.044299467 0.017697176 −11.78001292 10.827818 9.352605 9.831767 5.579836 7.269549 6.931222 SEMA4A −0.734871863 0.04729774 0.026737666 −11.82502362 7.931391 10.819306 13.346454 6.395481 7.767462 7.255535 NRG1 −0.647329085 0.05166843 0.035505274 −11.8274553 5.753024 10.308872 5.225216 1.661149 4.131418 5.426231 CDC42EP2 −0.943333341 0.043921714 0.014238176 −11.87717713 7.701538 6.391145 6.861515 1.661149 4.131418 3.630092 KDM5C −0.750093793 0.046662281 0.025587615 −11.93153419 10.36466 10.461284 10.371139 9.094145 6.794431 5.900694 BASP1 −0.868052485 0.044335719 0.017976863 −11.94669494 12.530995 10.601206 13.170085 7.582358 9.009341 8.952456 GPR25 −1.00510973 0.043588662 0.011653624 −11.96284627 5.856559 6.502398 6.670675 1.661149 3.134528 2.921909 LMAN2L −1.029483684 0.043577906 0.010575706 −12.03573496 9.779028 9.694786 9.86559 5.095353 6.189775 6.649696 HNRNPKP3 −1.024771671 0.043577906 0.010804355 −12.12159303 14.357511 14.344939 14.529844 10.758004 10.566282 11.290318 SNAI3 −0.957058973 0.043835088 0.013569241 −12.14718943 5.263699 6.139057 9.68794 1.661149 3.134528 2.921909 CDH24 −0.807003915 0.045297753 0.021579449 −12.17412993 7.177073 7.664061 7.107458 1.661149 3.571326 5.900694 HPS6 −0.777722197 0.045844227 0.023478054 −12.17543811 8.203921 6.957749 6.527811 5.705318 3.134528 2.921909 PSMD1 −0.924813727 0.044086036 0.015119428 −12.22942345 13.103806 12.216545 11.53143 8.604261 8.469821 9.346832 KIFC3 −0.715475756 0.047877006 0.02828445 −12.27806209 8.78396 9.546857 7.481604 1.661149 5.165949 7.943848 GHRLOS2 −0.821991541 0.045048325 0.020611092 −12.36684512 6.306772 6.762934 7.339085 1.661149 3.134528 5.091834 FGFBP1 −0.600154281 0.056344664 0.042819326 −12.38424163 6.381847 10.0858 6.012527 4.739845 2.265287 6.455366 SF3B4 −0.926180292 0.04406867 0.015047295 −12.43372566 11.756044 11.05205 10.707953 8.105092 8.119857 6.924055 MAP4K4 −1.056430273 0.043540291 0.00970262 −12.45466341 12.193312 12.09973 12.554998 8.105092 8.916384 8.705744 CNPY3 −0.931431291 0.044025007 0.014750595 −12.46099728 11.072716 10.582331 9.640971 6.550689 7.414086 6.942983 C7orf43 −0.877188968 0.044280042 0.017562436 −12.46103997 9.344671 9.2447 9.421041 5.705318 5.509998 7.03218 YY1AP1 −0.955856313 0.043840967 0.01364818 −12.47792987 9.967577 9.740906 10.602695 5.728038 7.406567 6.32627 EIF3J −0.947888626 0.043900827 0.014008166 −12.54518237 10.925179 12.226035 11.918273 8.331873 8.160956 8.269212 SRRT −1.020650926 0.043577906 0.011028921 −12.56768236 12.068161 12.530645 12.261635 7.210813 8.609988 9.257878 SLC1A3 −0.769165749 0.046096091 0.024117727 −12.67749036 6.45321 8.454859 9.067696 4.718672 5.165949 4.790662 LRRC56 −0.969518722 0.043726704 0.013016672 −12.70546935 5.328526 5.789702 6.704285 1.661149 2.265287 2.921909 TKTL1 −0.986582687 0.043626235 0.012306907 −12.81241608 7.238972 5.340619 7.003286 1.661149 2.265287 3.630092 LRP8 −0.885440498 0.044203301 0.017209935 −12.85072154 6.45321 6.605686 4.449894 1.661149 2.265287 2.921909 MAF1 −1.026815045 0.043577906 0.010695475 −12.89396502 12.070291 10.899437 11.34019 7.210813 7.740604 8.095288 DECR2 −1.056860541 0.043540291 0.009682205 −12.9116065 9.186094 9.626816 9.773571 1.661149 5.936219 6.106561 CCDC127 −1.019245899 0.043577906 0.011083362 −12.97457427 9.594014 9.572589 9.203198 1.661149 6.373501 5.874974 ZNRF1 −0.965993219 0.043778104 0.013146649 −12.97469283 10.249071 9.173617 10.627001 5.252045 6.551443 6.942983 TGFB2 −0.915168616 0.044110923 0.015578088 −12.99833211 8.323035 10.586546 10.992779 5.320955 7.292524 5.580533 CCNJ −0.922852723 0.044091888 0.015198367 −13.00499235 7.134281 5.362142 6.072169 1.661149 3.134528 2.921909 SECISBP2 −1.028574022 0.043577906 0.010620619 −13.03291582 11.478722 10.821096 10.467286 5.891233 7.191402 7.774634 ZDHHC14 −0.842888254 0.044657496 0.019260293 −13.06360376 9.44876 9.821812 9.627892 4.341916 5.920411 7.873743 GTF2IRD1 −0.981673862 0.043626235 0.012511058 −13.07334317 9.377152 9.502922 8.874506 6.339437 5.165949 5.580533 UBE2J2 −1.011487011 0.043581008 0.011388908 −13.09284144 10.410216 10.324102 9.972928 1.661149 6.613395 7.255535 RHOD −0.833349241 0.044797567 0.019823069 −13.26212076 8.527038 10.227521 7.519866 6.396698 4.797798 4.562324 PPP2R5B −0.964014386 0.043778104 0.013201089 −13.28472356 9.914819 9.377149 8.467835 6.183122 5.353925 5.446557 PEA15 −1.073181109 0.043516135 0.009162981 −13.28795009 12.40389 12.918293 12.772165 9.040118 9.275744 8.456743 ERI3 −0.909441273 0.044173036 0.015953045 −13.30211683 11.286905 10.783028 9.556058 5.705318 7.414086 7.553321 ZNF692 −1.073278176 0.043516135 0.009156176 −13.30372337 9.61362 9.439076 9.986654 5.705318 6.043524 6.195186 TSPYL2 −0.968532823 0.043738451 0.01304117 −13.30543365 14.743536 13.80924 15.607453 10.075297 10.570102 11.927244 ABCD1 −0.993376032 0.043626235 0.012075536 −13.31905803 8.274593 7.34377 8.751261 4.894482 4.539173 3.676349 DCTN2 −1.006856732 0.043588662 0.011592378 −13.32448975 12.319851 11.813562 10.991078 8.270632 8.077554 7.774634 DGKQ −0.94675307 0.043900827 0.014062606 −13.34847138 6.873131 6.931478 6.410545 1.661149 3.134528 4.146207 RPS6 −0.825668069 0.044949653 0.020396734 −13.37289001 17.351942 18.282063 17.649163 13.610703 13.848762 15.900822 GRPEL1 −1.059283312 0.043540291 0.009566519 −13.43796723 10.145127 10.742039 10.672298 7.109557 6.189775 6.924055 SLC27A4 −0.65874018 0.050764584 0.033922423 −13.44265457 7.198002 6.670655 2.995681 1.661149 3.134528 2.921909 AKNA −1.024486824 0.043577906 0.010845185 −13.46698742 12.286038 12.688032 13.435161 9.012327 7.819723 9.683805 CD276 −0.956046878 0.043840967 0.01363457 −13.50636388 9.961469 8.586982 9.243773 4.718672 6.205902 5.882028 RARG −0.82992103 0.044925422 0.020127935 −13.55075859 7.410173 8.491292 8.102218 4.341916 6.043524 3.630092 RMND5B −0.922277371 0.044110923 0.015248044 −13.57246476 10.412457 9.683021 8.589765 6.550689 5.920411 5.634184 SH2B2 −1.029033121 0.043577906 0.010600204 −13.57522269 7.278811 7.664061 8.302077 1.661149 4.539173 4.146207 FOXF2 −0.96550394 0.043778104 0.013167064 −13.62109619 10.376185 8.868964 10.947875 1.661149 6.613395 7.180104 BEGAIN −0.95074642 0.043900827 0.01386526 −13.7170218 7.530567 9.09885 9.035041 5.320955 5.317867 3.676349 TIMM17A −1.084837505 0.043516135 0.008764206 −13.75513926 12.16834 12.206308 11.321356 7.877571 7.713236 8.424409 PRKDC −1.027481881 0.043577906 0.010647839 −13.77375536 11.916191 11.577679 10.834794 7.36523 7.793829 8.053616 ACHE −0.826813189 0.044930476 0.020298061 −13.82819362 6.054828 6.502398 6.012527 1.661149 2.265287 4.476242 PLXNB1 −1.007108262 0.043588662 0.011585573 −13.99273059 10.581282 11.450453 9.725263 6.651882 6.774676 7.03218 GPIHBP1 −0.698926541 0.048753782 0.029967336 −14.06179919 7.656883 6.904719 6.948237 1.661149 3.134528 6.73963 NOTCH2 −0.944446097 0.043921714 0.014156516 −14.17400232 10.785229 12.016244 12.296494 6.960054 9.02055 7.825039 AEN −0.914378592 0.044110923 0.015618918 −14.34805458 9.700528 9.891622 9.155384 4.802615 5.857745 7.218312 CCDC71 −0.908254349 0.044173537 0.015988431 −14.35350285 8.638422 8.319573 7.4423 1.661149 5.920411 4.476242 MAPKAPK2 −0.851837925 0.044480228 0.018773733 −14.37563566 12.910092 12.532285 13.428261 7.877571 9.064538 11.146572 MAP1LC3B2 −1.013609747 0.043581008 0.011334468 −14.39637365 7.814275 7.87177 8.939468 1.661149 4.608763 5.091834 RPL9 −1.073454789 0.043516135 0.00913576 −14.483567 16.388277 17.351906 16.857923 12.897666 13.495561 12.534993 C1R −1.048729508 0.043577906 0.009984348 −14.51018605 13.648655 12.771872 13.628963 8.033165 9.956624 9.769968 BCKDK −1.068745814 0.043516135 0.009305886 −14.55433223 11.614337 10.762679 10.236878 7.037879 6.373501 7.291822 GIGYF1 −1.062952004 0.043516135 0.009441987 −14.58828895 10.844508 10.684201 10.728522 4.739845 6.861783 7.611911 IRX4 −0.87895133 0.044278935 0.017483498 −14.74875362 7.09018 8.028729 5.225216 1.661149 3.134528 4.146207 FMNL3 −0.982157595 0.043626235 0.012497448 −14.78047187 10.416927 9.128067 11.065724 5.891233 5.936219 7.180104 EIF5AL1 −1.081402142 0.043516135 0.008890779 −14.79727798 14.320856 15.05024 14.224426 11.040784 10.669588 10.337166 GLO1 −0.972089196 0.043681142 0.012899626 −14.89806937 13.235233 13.037804 11.663346 8.801178 8.855089 9.33818 PRRC2B −1.080495755 0.043516135 0.008952024 −14.97943202 12.419569 12.572694 12.705768 8.514658 8.65384 9.267025 TULP4 −0.952405847 0.043900827 0.013791085 −15.01706419 7.298325 8.065438 7.538623 1.661149 5.306419 3.630092 CDKN2A −0.862042017 0.044379352 0.018299422 −15.08732497 9.533543 8.016282 8.477589 1.661149 7.174648 4.562324 ENDOG −1.072779627 0.043516135 0.009183396 −15.09123057 9.048812 9.007473 8.279951 1.661149 5.306419 5.091834 EFHD2 −1.046638338 0.043577906 0.010066009 −15.09954913 11.422029 12.292707 12.593633 8.069577 7.505595 8.906373 RASSF7 −0.943233062 0.043921714 0.014244981 −15.2198587 7.854379 9.864102 9.537526 4.739845 5.936219 5.426231 CKB −1.0151566 0.043581008 0.011252807 −15.22458362 11.905096 13.183736 13.589027 7.976765 8.36819 10.033825 STX4 −1.075011215 0.043516135 0.009101735 −15.23038947 11.60163 11.210685 12.069434 6.550689 8.140553 7.96648 C10orf35 −0.692128138 0.048955004 0.03048656 −15.36143612 7.134281 8.417483 3.764125 1.661149 3.134528 4.476242 TNFRSF18 −0.749980379 0.046675232 0.025603266 −15.36212782 5.263699 8.889584 8.659978 4.718672 3.134528 4.790662 NES −1.070790332 0.043516135 0.009217421 −15.50672082 11.349047 13.189984 13.185046 7.394225 8.098861 9.23941 MAZ −1.028964463 0.043577906 0.010607009 −15.51030385 12.214011 11.323596 12.539366 7.36523 8.258856 8.784285 TMEM63B −0.994582774 0.043626235 0.012048316 −15.60673845 9.191323 9.737119 9.692135 5.728038 4.797798 6.722123 THAP4 −1.136729434 0.043453389 0.00720313 −15.70473206 11.478722 11.476811 10.648749 7.037879 7.505595 6.931222 SPSB1 −1.046681961 0.043577906 0.010052399 −15.75890155 10.767835 10.95593 12.151699 8.173604 7.191402 5.882028 PJA1 −0.942363982 0.043921714 0.014272201 −15.76461021 9.071674 8.454859 8.345336 1.661149 6.549959 4.476242 DDR2 −0.985088969 0.043626235 0.012368152 −15.77402551 10.622509 9.489477 8.534767 1.661149 5.509998 6.942983 RBM15B −1.162640786 0.043453389 0.006549847 −15.77800333 10.398961 10.012489 9.86187 6.252746 6.189775 5.882028 EIF4G1 −1.096020408 0.04349335 0.008357945 −15.80072094 10.177104 10.293481 9.390389 5.743334 6.237456 6.195186 HIP1R −1.03372532 0.043577906 0.010425995 −15.82965244 9.886086 11.882049 11.102436 6.395481 6.043524 7.897492 ZNF219 −1.001427809 0.043588662 0.01181014 −15.85743752 9.296962 9.555485 8.726933 4.739845 6.373501 5.106393 ACSL4 −1.156094605 0.043453389 0.006713168 −15.90256621 9.927407 9.555485 9.405796 5.579836 5.936219 3.630092 GPATCH3 −1.020827228 0.043577906 0.011015311 −15.9601516 8.831618 8.535576 8.050877 1.661149 4.539173 5.634184 MFSD10 −1.064358609 0.043516135 0.009414767 −16.07428577 11.641333 11.904174 10.813772 7.450526 7.56803 7.897492 RAI14 −1.025216116 0.043577906 0.01078394 −16.08080906 10.380769 10.59075 9.155384 4.894482 6.373501 6.722123 MRTO4 −1.14156161 0.043453389 0.007073835 −16.08299318 11.057048 11.705291 10.557423 7.210813 6.549959 7.152205 ANKRD11 −1.020984919 0.043577906 0.010994896 −16.15549982 12.126645 12.491837 12.328512 7.607339 8.314558 9.454835 UBASH3B −0.873508987 0.044299467 0.017710786 −16.18672861 7.595107 9.874484 10.629191 5.026959 5.857745 6.195186 KDM2A −1.109797134 0.043485739 0.007921742 −16.30309268 12.44003 11.907548 12.304737 7.631894 8.277663 8.771488 REXO4 −0.641884838 0.052014843 0.036263355 −16.41415912 8.183076 8.288855 6.012527 1.661149 7.107836 4.146207 TSG101 −1.040524424 0.043577906 0.010303505 −16.42813514 12.904531 11.620455 10.577971 7.582358 7.91889 7.36177 DAXX −1.192434448 0.043453389 0.005903368 −16.52748781 12.180223 12.596406 12.270078 8.139755 8.140553 8.549611 CTPS −0.959060726 0.043826549 0.013449473 −16.55716654 10.112425 10.235597 9.421041 6.063041 5.306419 7.291822 PIEZO1 −1.115733968 0.043485739 0.007717591 −16.56325923 10.264036 10.701797 10.804114 6.651882 7.094585 6.129407 C1orf51 −1.01690307 0.043581008 0.011177952 −16.69247905 9.4134 10.124007 10.10465 4.894482 6.043524 6.924055 RIPK1 −1.095481392 0.04349335 0.008385165 −16.77404198 10.305614 9.564062 9.118454 4.718672 6.237456 5.580533 ANAPC1 −1.0672441 0.043516135 0.009339912 −16.77781072 10.145127 10.094707 10.120301 4.894482 7.066159 6.051818 RRP9 −1.142206242 0.043453389 0.007039809 −16.9311492 8.884223 10.046553 8.685452 4.802615 4.608763 5.446557 MID1IP1 −1.146362147 0.043453389 0.006937734 −16.93907577 8.691047 8.473191 9.061224 1.661149 4.608763 5.106393 SLC29A1 −1.092361129 0.04349335 0.008514461 −16.94405603 11.453921 11.803637 10.857383 7.976765 6.774676 7.327219 B4GALT2 −1.089244207 0.043516135 0.0086213 −16.98860911 9.961469 10.243628 9.485302 4.718672 6.608026 5.874974 SAP25 −0.988406832 0.043626235 0.012238857 −16.99845029 7.968408 8.147628 9.945076 1.661149 5.857745 4.790662 FBXO10 −1.081182402 0.043516135 0.008911194 −17.06596987 8.224469 7.952383 8.571664 1.661149 4.131418 5.106393 TRAF7 −1.060864469 0.043540291 0.009512079 −17.25905194 11.503105 11.300684 10.459924 6.183122 7.191402 7.800057 LOC729603 −1.139947577 0.043453389 0.007169105 −17.27713913 9.217186 8.417483 8.467835 1.661149 4.539173 5.106393 ATP6V0B −1.111261559 0.043485739 0.007860497 −17.29715697 12.871118 12.069927 12.61754 7.957464 8.296229 9.133378 CIB2 −1.101744465 0.04349335 0.008153794 −17.34565645 9.470427 9.173617 10.166259 1.661149 5.353925 6.32627 GPRIN1 −1.00821412 0.043581008 0.011490983 −17.34634806 6.381847 6.792427 6.031658 1.661149 2.265287 3.630092 ALDOA −1.201834655 0.043453389 0.005570602 −17.36183889 14.676022 14.551526 13.910595 9.799885 9.939008 10.558174 FAM180A −0.884246506 0.044223984 0.017266417 −17.36704887 5.779429 6.502398 7.4423 1.661149 2.265287 4.562324 SOX8 −0.833637233 0.044797567 0.019789044 −17.36704887 5.779429 6.391145 8.981205 1.661149 4.539173 3.630092 CRISPLD2 −0.895320384 0.044203301 0.016733583 −17.3987106 14.783358 14.269426 14.861804 7.394225 10.66245 12.877926 HSD17B10 −1.035669627 0.043577906 0.01039197 −17.51235631 11.219408 10.964054 9.578892 5.448591 6.774676 7.218312 AP1S1 −0.941857198 0.043921714 0.014299422 −17.53047974 8.922456 7.726519 6.861515 1.661149 4.608763 4.790662 TCP11L1 −1.124927939 0.043453389 0.007454917 −17.58504269 9.640629 9.302226 8.562528 5.252045 5.165949 5.106393 SLC4A3 −1.046659297 0.043577906 0.010059204 −17.73682739 6.924263 8.943172 7.825025 2.820813 4.608763 3.676349 DENND1A −0.95622193 0.043840967 0.013614154 −17.74931675 10.475962 8.790733 8.458015 1.661149 5.857745 6.32627 FZD5 −1.029052588 0.043577906 0.010593399 −17.87868598 8.518743 9.480443 10.355354 4.341916 5.509998 6.195186 KCNH3 −0.958595483 0.043826549 0.013469888 −17.88243156 7.155835 7.08238 6.054038 1.661149 4.131418 2.921909 UCK2 −1.02738692 0.043577906 0.010661449 −18.10087642 6.973646 8.309406 6.83141 1.661149 4.131418 3.630092 SLC25A25 −1.078167348 0.043516135 0.009020075 −18.2077769 11.325462 11.233716 12.341256 6.396698 7.138979 8.564524 NXF1 −0.984411763 0.043626235 0.012395373 −18.26795942 13.187953 14.286857 14.48989 8.616619 10.095614 11.202466 KIF1A −1.083501194 0.043516135 0.008822729 −18.32079214 5.856559 8.676719 6.012527 1.661149 2.265287 2.921909 HIVEP3 −0.949154065 0.043900827 0.013926506 −18.4446431 8.351337 10.311422 10.726478 7.243046 5.509998 4.146207 SS18L2 −1.218312091 0.043453389 0.005237155 −18.45254373 12.426237 12.431008 12.913159 8.616619 8.220489 8.407967 BRF1 −1.24466661 0.043453389 0.004767608 −18.4713131 10.266516 9.935252 10.334036 5.728038 6.189775 5.874974 BCL2L11 −1.166125577 0.043453389 0.006495407 −18.52011489 11.633671 11.248425 12.191507 7.42265 8.011679 6.73963 FLNA −1.086523174 0.043516135 0.00873018 −18.57989161 13.080394 13.7137 13.244097 8.864724 8.998044 10.166824 ELTD1 −0.795427379 0.04540117 0.022331405 −18.63973708 10.150506 9.538176 10.295954 5.320955 5.317867 8.809543 SAA1 −1.006095589 0.043588662 0.011626404 −18.6799756 11.637507 13.081773 9.887706 7.918071 7.414086 6.455366 ACCN3 −1.120093471 0.043485739 0.007588295 −18.8598055 7.980539 8.398425 9.035041 1.661149 4.797798 4.562324 TMUB1 −1.081510223 0.043516135 0.008883974 −18.96214266 10.857723 10.351611 9.996864 7.25991 5.509998 6.106561 HSPG2 −1.050837409 0.043568903 0.009908813 −19.00163023 10.856078 10.762679 11.299525 5.448591 6.608026 8.155622 FANCB −0.837544399 0.044763248 0.019623682 −19.10558612 6.52121 6.03611 6.737132 1.661149 2.265287 4.790662 FADS1 −0.680143431 0.049490097 0.031618237 −19.10635158 11.896318 7.843866 6.976024 1.661149 6.043524 7.640338 TBRG4 −1.132698065 0.043453389 0.007277986 −19.11332195 11.567856 11.667979 10.493962 6.954147 6.237456 7.668215 REPIN1 −1.198428402 0.043453389 0.005727118 −19.59828051 11.479791 11.452764 10.703803 7.074163 7.187136 6.722123 PDPN −0.948648322 0.043900827 0.013960531 −19.6204415 9.840223 9.337675 9.400679 1.661149 7.656894 5.106393 NPW −1.181567785 0.043453389 0.006141545 −19.69267187 6.186289 7.218985 6.564874 1.661149 2.265287 2.921909 ZBTB7B −1.222990056 0.043453389 0.00513508 −19.76735252 10.254077 10.445123 9.753639 5.448591 6.189775 5.874974 CRABP2 −0.962688698 0.043778104 0.013255529 −19.89380202 11.527082 14.393872 14.306583 8.566539 10.079625 9.257878 HSD11B1 −1.097383211 0.04349335 0.00831031 −20.12272642 10.414694 9.542523 10.251164 1.661149 5.920411 6.73963 PEAK1 −1.025388024 0.043577906 0.010777135 −20.20403416 10.288639 11.992611 12.57558 7.656039 7.68534 7.46072 XIRP1 −0.972220384 0.043681142 0.012886016 −20.27198211 5.658609 7.965391 8.903739 2.820813 2.265287 4.562324 MARS −1.026758202 0.043577906 0.010709085 −20.57109723 12.507608 12.018586 10.394496 7.656039 7.53715 7.800057 LRCH4 −1.088113716 0.043516135 0.00867574 −21.12023628 10.870817 11.257708 11.353494 6.857154 6.373501 8.03232 NRN1L −0.77868838 0.045838382 0.023409323 −21.28089657 6.949166 6.072636 6.704285 1.661149 2.265287 5.446557 CXorf65 −1.140229962 0.043453389 0.00714869 −21.2879603 11.739185 10.936243 10.279321 5.095353 6.774676 7.327219 LDLRAD2 −0.895309444 0.044203301 0.016740388 −21.30473308 6.678389 6.228068 7.156853 1.661149 2.265287 4.790662 FGFRL1 −1.211118333 0.043453389 0.005414086 −21.38367043 9.659616 11.021236 10.309671 5.891233 6.189775 5.634184 PPARD −1.091552864 0.0435113 0.008566179 −21.52092138 10.690553 11.500464 10.979111 1.661149 6.551443 8.03232 ST7-AS1 −1.154802289 0.043453389 0.006733583 −21.53587326 7.563198 6.702075 6.564874 1.661149 3.134528 2.921909 C11orf91 −0.827858518 0.044930476 0.02024362 −21.71146222 7.238972 8.916627 8.974332 6.814118 2.265287 4.476242 NSMCE1 −0.996689812 0.043626235 0.011966655 −21.96907954 8.294165 8.028729 6.891005 1.661149 3.571326 5.091834 SCAP −1.058649799 0.043540291 0.009580129 −21.97318011 9.792853 9.019996 8.467835 1.661149 6.319269 4.562324 IER3 −1.178994645 0.043453389 0.006195985 −21.99339825 13.331022 14.646838 14.300241 8.711848 9.841243 10.19585 GPR133 −1.067957459 0.043516135 0.009312691 −22.28357469 8.332531 6.139057 7.580498 1.661149 4.131418 2.921909 C11or96 −1.04112008 0.043577906 0.010269479 −22.29903859 16.640765 14.974649 16.285645 10.771883 10.495739 13.322651 CDK16 −1.350035981 0.043453389 0.003079959 −22.64426987 12.430665 12.496885 12.174366 7.995811 7.767462 7.748756 FBXW5 −1.214274742 0.043453389 0.005332426 −22.70790464 13.284993 12.573225 11.899348 7.394225 7.440337 8.870819 FAM41C −1.172089952 0.043453389 0.006359306 −22.81593236 8.284413 8.949732 8.525393 4.013424 3.571326 5.091834 SEMA3B −0.897269661 0.044203301 0.016620619 −23.29325466 7.595107 11.129218 10.265311 5.320955 5.306419 6.587378 RGS12 −1.111885411 0.043485739 0.007846887 −23.49858062 9.806546 10.634165 10.881463 5.252045 5.317867 7.395512 ZNF384 −1.331186761 0.043453389 0.003372576 −23.74022157 11.156639 11.236402 11.108726 5.026959 6.774676 6.587378 FHL3 −1.218555443 0.043453389 0.00523035 −23.81693238 10.145127 10.521976 10.47461 1.661149 6.319269 5.900694 FBXL8 −1.239645557 0.043453389 0.004822048 −23.83934302 7.497182 6.572071 6.564874 1.661149 2.265287 2.921909 SKI −1.136238445 0.043453389 0.00721674 −23.8401672 10.632154 10.695955 11.755426 4.718672 7.138979 7.180104 FOXC2 −1.020499187 0.043577906 0.011035726 −23.86175684 8.0045 7.711156 6.369239 1.661149 3.134528 4.476242 ADC −1.014326805 0.043581008 0.011300442 −23.94364826 7.730559 9.190335 9.619106 1.661149 4.608763 6.106561 NOL6 −1.089511108 0.043516135 0.008614495 −24.05797353 8.934978 10.640261 9.509275 1.661149 5.857745 6.051818 HHIPL1 −0.970941699 0.043709154 0.012949302 −24.18814023 7.980539 6.849665 6.861515 1.661149 2.265287 5.091834 RAB11FIP5 −1.26668748 0.043453389 0.004345696 −24.45398266 7.355332 6.877454 7.746525 1.661149 3.134528 2.921909 SLC43A3 −1.118954647 0.043485739 0.007622321 −24.46831038 13.900662 12.612518 11.918273 7.30543 7.440337 9.642233 SHOX2 −0.978590593 0.043661316 0.012598843 −24.5047815 9.700528 8.761199 10.43761 4.894482 7.269549 4.146207 ABLIM2 −0.983947884 0.043626235 0.012408983 −24.72747266 8.459303 7.303362 7.762571 1.661149 3.134528 5.634184 TMEM222 −1.285803674 0.043453389 0.00412113 −24.87311261 11.735611 11.421245 10.782636 6.651882 6.78473 6.924055 PLA2G2A −0.632746025 0.052998119 0.037717591 −24.92344671 1.874444 6.904719 7.746525 1.661149 2.265287 2.921909 HMOX2 −1.187150649 0.043453389 0.006025859 −24.98353047 11.750741 11.782661 10.825276 5.252045 7.107836 7.668215 YTHDF2 −1.393479198 0.043453389 0.002501531 −25.0046254 12.815486 12.972053 12.867057 8.222933 8.385634 7.825039 ZFP41 −1.175461264 0.043453389 0.00627084 −25.39003807 7.730559 6.931478 6.636262 1.661149 2.265287 3.630092 S100A3 −1.075714839 0.043516135 0.00908132 −25.80324952 7.238972 8.319573 5.592916 1.661149 2.265287 3.630092 HSF1 −1.290214015 0.043453389 0.004053079 −25.83329037 11.465836 12.206993 11.055992 6.396698 6.774676 7.36177 EXT1 −1.318299792 0.043453389 0.003603947 −25.9066643 11.772709 12.592743 12.054033 7.25991 7.187136 7.897492 PHB2 −1.307973855 0.043453389 0.003753658 −26.42307271 14.446432 14.778544 14.188872 9.002943 9.722706 10.350135 TMBIM1 −1.348326147 0.043453389 0.003113984 −27.25902992 13.336931 12.66579 12.425557 8.087444 7.656894 8.287303 CXCR7 −1.1813783 0.043453389 0.00614835 −27.2651573 12.246398 12.024036 10.910557 1.661149 7.25505 7.748756 ATP6V0C −1.384655155 0.043453389 0.002671657 −28.10583583 13.775701 14.458412 14.410962 9.645614 9.375155 9.051056 SETD8 −1.298601103 0.043453389 0.003957809 −28.54854148 11.569865 12.022481 12.134846 6.498222 7.187136 7.825039 SNORD36C −1.31106347 0.043453389 0.003719633 −28.59802369 11.305107 12.608895 12.474479 7.771052 7.066159 6.924055 ELK1 −1.032984883 0.043577906 0.010466825 −28.83483774 8.89708 7.77165 7.250844 1.661149 5.509998 2.921909 PANK4 −1.193406119 0.043453389 0.005855733 −28.8469234 10.685004 10.852945 10.786565 1.661149 5.936219 7.180104 PRRX2 −1.235962298 0.043453389 0.004876489 −28.91781073 11.472293 10.914608 12.199633 5.095353 7.740604 6.618407 CAPZB −1.364032662 0.043453389 0.002896223 −29.1339417 14.504558 13.770854 13.621833 8.757204 9.218487 9.363984 EXTL3 −1.270357757 0.043453389 0.004264035 −29.54570421 11.92955 10.821096 9.658228 5.252045 5.936219 6.195186 ZFPM1 −1.200479042 0.043453389 0.005665873 −29.66208903 7.155835 7.965391 6.601009 1.661149 2.265287 3.630092 POLR3E −1.225860926 0.043453389 0.00505342 −29.78040556 9.26756 9.686953 9.913086 1.661149 5.857745 4.790662 SHF −1.332459126 0.043453389 0.003338551 −29.99913145 9.164988 9.038579 9.704647 1.661149 4.797798 4.476242 MIIP −1.034773197 0.043577906 0.010412385 −30.2576043 7.841135 7.843866 7.646315 1.661149 5.353925 2.921909 BCAR1 −1.159990054 0.043453389 0.006617897 −30.50092012 10.266516 11.130663 10.788525 4.802615 5.857745 7.46072 OGFOD2 −1.193521761 0.043453389 0.005848928 −30.52268767 7.513971 7.197097 6.670675 1.661149 2.265287 3.630092 HDGF −1.133928581 0.043453389 0.007243961 −30.57849285 10.117927 9.276362 9.532856 4.341916 6.549959 4.476242 SEC61A1 −1.363308609 0.043453389 0.002916638 −30.7493823 13.931844 13.098107 12.46409 7.631894 8.486085 8.155622 HAPLN3 −1.230310392 0.043453389 0.004971759 −31.2273392 11.071298 12.143311 12.243884 7.957464 7.066159 6.106561 SLC45A4 −1.170956648 0.043453389 0.006400136 −31.5663239 8.55164 8.841005 8.487278 1.661149 3.571326 5.446557 AKT1 −1.363188046 0.043453389 0.002923443 −31.91557789 12.030002 11.492623 11.352169 4.718672 6.794431 7.033813 CXCL1 −1.208205327 0.043453389 0.005461722 −32.00179074 10.920464 11.648955 11.55004 7.792994 6.549959 5.874974 NRBP1 −1.307401639 0.043453389 0.003760463 −32.29750587 12.648754 12.047164 11.901161 8.190235 6.794431 7.033813 PAPPA −1.151081904 0.043453389 0.006842463 −32.79983607 12.906519 10.931279 10.287661 5.252045 6.373501 7.695565 HPDL −1.291325831 0.043453389 0.004039469 −32.97913878 7.513971 7.965391 6.282905 1.661149 2.265287 2.921909 POM121 −1.269466165 0.043453389 0.00428445 −33.32239888 7.278811 7.323707 7.481604 1.661149 2.265287 3.630092 ST14 −1.232366179 0.043453389 0.004930929 −33.40774621 8.638422 11.11031 7.98402 4.341916 4.539173 2.921909 CSF1 −1.473909726 0.043453389 0.001711466 −33.98864293 13.012599 12.359516 13.053461 7.30543 7.56803 7.96648 ZNF385A −1.299184197 0.043453389 0.003951004 −34.43309341 10.734196 10.132682 11.229095 5.026959 5.353925 6.73963 SLC7A5 −1.305999732 0.043453389 0.003780878 −35.08488101 12.236315 13.12154 11.865388 7.748771 6.237456 7.988762 ZC3H18 −0.905115471 0.044173537 0.016178972 −35.30928419 8.183076 7.756763 8.063885 1.661149 6.608026 2.921909 SIN3A −1.322824336 0.043453389 0.003522286 −35.68378214 12.222974 11.787247 12.905953 6.244586 7.740604 7.748756 SLC39A13 −1.327805815 0.043453389 0.003440626 −35.71742924 11.708516 11.855218 11.378439 1.661149 6.549959 7.020304 NCOR2 −1.27663494 0.043453389 0.0042164 −35.77252063 11.08119 10.368847 11.361418 4.739845 5.920411 7.020304 TNFRSF12A −1.304907735 0.043453389 0.003808098 −36.69515947 11.133737 13.199649 12.063779 8.087444 5.936219 6.195186 CNTFR −1.361643045 0.043453389 0.002937053 −36.76125981 7.893399 7.08238 8.334642 1.661149 3.134528 2.921909 PVRL1 −1.148962222 0.043453389 0.006890099 −36.88137962 8.129608 9.767145 10.27653 1.661149 5.936219 4.562324 SDF4 −1.433115184 0.043453389 0.002106159 −37.50406544 12.606325 12.242159 11.568413 6.339437 7.138979 7.255535 ERLIN1 −1.311211592 0.043453389 0.003712827 −38.04139106 11.704864 11.23506 11.748393 1.661149 7.094585 6.455366 CCT2 −1.538505871 0.043453389 0.001384825 −38.08842211 14.53752 15.45363 14.74438 9.4931 9.666725 9.303041 PPP1R14B −1.407572375 0.043453389 0.00233821 −38.5002184 13.46846 13.959023 12.774145 8.139755 8.055928 8.692228 MAP7D1 −1.349231338 0.043453389 0.003100374 −38.67748926 13.436616 14.192165 13.634968 8.361545 8.033973 9.628105 TNFRSF4 −1.40968292 0.043453389 0.00231099 −39.28100822 10.70342 9.803819 11.231979 4.739845 5.936219 5.091834 PRRC2A −1.442498163 0.043453389 0.002004083 −39.56084343 11.946657 12.217905 12.080677 4.718672 6.774676 7.327219 CTU2 −1.423300168 0.043453389 0.002194624 −40.08971128 9.272502 9.291936 8.896486 4.739845 3.571326 3.676349 ANAPC2 −1.172340152 0.043453389 0.006352501 −40.21352716 8.959701 7.87177 8.967426 5.252045 2.265287 3.630092 MFSD7 −1.331296213 0.043453389 0.003365771 −40.25576082 9.296962 9.007473 8.506461 1.661149 4.797798 3.676349 CSNK2A1P −1.361038187 0.043453389 0.002950663 −40.59144864 11.263514 11.477946 10.994478 1.661149 5.920411 6.618407 CYB5R2 −1.22853843 0.043453389 0.005012589 −40.6566729 10.192831 10.465868 9.021769 4.739845 6.205902 3.676349 ACOT7 −1.24679747 0.043453389 0.004713168 −41.98246996 10.286197 11.331154 11.252009 4.894482 5.509998 7.352555 OPLAH −1.340798956 0.043453389 0.00322967 −42.18604746 9.344671 9.075043 8.767255 5.026959 3.134528 3.676349 FOSL1 −1.578582579 0.043453389 0.001201089 −42.5594008 11.796921 12.737687 11.624364 6.550689 6.237456 6.385515 C11orf84 −1.249683431 0.043453389 0.004638312 −42.64502612 10.66635 8.644729 11.819147 5.252045 4.797798 5.426231 RECQL4 −1.403093335 0.043453389 0.002406261 −44.05494592 6.792865 7.726519 8.553333 1.661149 2.265287 2.921909 CSK −1.314023 0.043453389 0.003651582 −45.73401893 11.025194 11.073236 10.452524 1.661149 5.509998 6.649696 FST −1.445737051 0.043453389 0.001990473 −45.96670366 13.420009 13.268836 11.534938 6.339437 6.640994 7.897492 NAP1L4 −1.373536741 0.043453389 0.002794148 −48.01070264 12.722389 13.45184 13.090879 6.857154 7.505595 8.929599 GSC −1.351460142 0.043453389 0.003066349 −48.75422278 9.237547 7.494953 8.553333 1.661149 3.571326 3.630092 PRICKLE3 −1.54664631 0.043453389 0.001316774 −49.935035 8.705736 8.962765 9.272072 1.661149 3.571326 3.630092 ARF1 −1.605830256 0.043453389 0.001085403 −50.91201485 16.051263 15.850516 15.232693 9.873821 10.434198 9.562759 ABL1 −1.506656192 0.043453389 0.001548146 −50.92899856 13.422234 12.980487 13.207566 6.244586 7.53715 8.374509 TMEM150A −1.540384415 0.043453389 0.00137802 −52.03248383 10.581282 10.064799 10.420013 4.718672 4.131418 5.426231 EDNRB −1.369959472 0.043453389 0.002828173 −52.63071575 16.024278 14.320468 14.511564 7.918071 9.680925 10.306444 ZC3H3 −1.458519677 0.043453389 0.001840762 −53.19539178 9.363321 9.538176 8.874506 1.661149 4.539173 3.630092 S100A7 −1.535053407 0.043453389 0.00140524 −54.29311465 7.918838 8.684606 7.462086 1.661149 2.265287 2.921909 SLC34A2 −1.258017636 0.043453389 0.004502212 −54.99206125 8.5104 11.827879 7.4423 1.661149 3.571326 4.476242 PDLIM4 −1.463502373 0.043453389 0.001786322 −56.56801751 12.788139 14.182623 12.679069 6.857154 7.56803 8.269212 RNF26 −1.376047641 0.043453389 0.002760122 −57.46658578 10.268991 9.634981 9.415978 5.705318 3.571326 3.630092 SMURF1 −1.518408267 0.043453389 0.001493705 −58.24779733 13.205502 13.492287 13.395192 7.531061 7.25505 8.636861 ADRA2C −1.143524541 0.043453389 0.007012589 −59.15827153 11.941236 8.848046 8.151795 4.341916 2.265287 5.882028 ITGB5 −1.366904937 0.043453389 0.002862198 −60.002217 14.842401 14.590751 13.301169 7.394225 8.436733 9.995819 TNFRSF1B −1.472508512 0.043453389 0.001718272 −60.18446343 12.961491 13.21675 13.609133 7.30543 6.373501 8.719135 MSC −1.356099743 0.043453389 0.003005104 −62.23007221 11.353718 9.342669 10.301457 4.341916 3.134528 6.129407 BCAN −1.646719651 0.043453389 0.000942497 −67.67595767 8.683645 7.74172 8.859664 1.661149 2.265287 2.921909 PARP10 −1.407416702 0.043453389 0.002345015 −68.37146334 10.24153 9.67116 10.862976 1.661149 5.920411 4.146207 TGFB1I1 −1.437336263 0.043453389 0.002051718 −68.60337821 13.445669 13.29161 12.446815 4.802615 7.191402 8.456743 PLAU −1.356315118 0.043453389 0.002998299 −70.03420822 13.422512 12.862886 11.047831 1.661149 7.292524 7.152205 NELF −1.533219697 0.043453389 0.001412045 −72.96003906 11.295428 11.542304 10.817617 1.661149 5.936219 5.106393 LOC493754 −1.592726357 0.043453389 0.001153454 −73.29259511 12.591076 13.027374 13.636057 6.395481 7.989035 6.69026 ST6GALNAC4 −1.477261866 0.043453389 0.001691051 −77.24943366 11.577872 10.256915 9.499733 1.661149 5.306419 4.476242 PTPN23 −1.625433235 0.043453389 0.001010548 −83.90736359 12.940685 13.016869 12.113109 5.252045 6.549959 7.291822 DEXI −1.676603098 0.043453389 0.000833617 −88.18520104 13.103459 13.16024 12.764217 5.728038 6.640994 7.611911 PPP1R18 −1.535851454 0.043453389 0.001398435 −92.43491901 13.531403 13.587389 15.153047 6.544171 8.350533 8.622681 G6PD −1.61893407 0.043453389 0.001030963 −94.50029597 13.572807 12.935748 12.358515 4.894482 6.373501 7.668215 KRBA1 −1.718073711 0.043453389 0.000690711 −97.23318603 9.525286 9.686953 8.355951 1.661149 3.134528 2.921909 RTN4RL2 −1.796707132 0.043453389 0.000561415 −102.4987363 8.78396 8.509169 9.601371 1.661149 2.265287 2.921909 SNX8 −1.469750014 0.043453389 0.001731882 −111.131302 10.205806 9.71803 8.889197 1.661149 5.165949 2.921909 C8orf82 −1.765416053 0.043453389 0.000622661 −130.174528 10.177104 9.651173 8.685452 1.661149 2.265287 3.630092 TEAD4 −1.565151516 0.043453389 0.001235114 −133.3551204 8.720278 9.663198 9.410896 1.661149 2.265287 4.476242 TRIM8 −1.837758629 0.043453389 0.000466145 −134.1110566 12.178907 11.176132 12.577282 5.095353 5.509998 5.106393 KLC2 −1.80152759 0.043453389 0.000547805 −137.5778808 10.734196 10.78119 10.402199 1.661149 4.539173 3.630092 PXDC1 −1.97287208 0.043453389 0.000255189 −181.3785395 13.835783 13.389565 14.655065 5.579836 6.549959 7.152205 PI4K2A −1.909491761 0.043453389 0.000343654 −181.6360591 12.905327 13.400383 14.195167 5.320955 6.640994 6.69026 NCS1 −2.158869699 0.043453389 0.000146308 −204.8049473 11.897918 12.105617 11.809525 4.894482 4.131418 4.146207 SCRIB −1.801281324 0.043453389 0.00055461 −224.0705541 10.942337 11.150732 10.697557 1.661149 3.134528 5.106393 MMP1 −1.679174554 0.043453389 0.000826812 −241.3496561 15.939572 12.046399 9.4756 1.661149 4.131418 4.790662 MMP3 −1.746023977 0.043453389 0.000656686 −465.624075 14.466518 12.539371 11.057619 1.661149 6.640994 3.676349 MMP12 −2.408034216 0.043453389 7.83E−05 −586.6006309 12.34294 11.169121 10.857383 1.661149 2.265287 2.921909

TABLE 9 Differentially Expressed Genes in CD10−, CD24−, CD44+ Breast Epthelial cells of BRCA2 Mutation Carriers ID t-value q-value p-value Fold change P1 P2 P3 BRCA2-N151 BRCA2-N161 BRCA2-N172 HSPA1A 2.011561712 0.04958755 0.000389152 2489.16994 2.993831 4.7365865 7.9976413 16.0180355 17.2726998 14.8795479 LOC642361 2.198386219 0.04958755 0.000172511 2137.354775 1.8744435 2.0230478 2.9956812 10.9516464 13.1605909 14.0572919 RPS29 2.280347449 0.04958755 0.000148439 1128.6294 4.309025 5.3621423 6.2829045 14.7874254 15.5024984 15.6669952 HNRNPA1 2.349268832 0.04958755 0.000124368 858.800101 3.0245043 2.0230478 2.1654208 11.7692264 12.0704905 12.5017958 MTRNR2L2 1.945683642 0.04958755 0.000493461 685.9243605 1.8744435 2.0230478 2.1654208 9.4518602 11.4449535 12.8355435 RPL23AP32 2.091154616 0.04958755 0.000284843 647.8613061 3.8197323 5.4346801 5.5446534 13.4958827 14.2869369 14.8841946 RPL27A 2.112261591 0.04958755 0.000268796 548.9609052 5.7794294 5.1480825 6.6706745 14.2486421 15.5219953 15.4572907 ERH 2.042512894 0.04958755 0.000349033 536.2523097 2.993831 2.0230478 2.1654208 11.3198595 10.3562848 12.0605992 COX6A1 1.966234652 0.04958755 0.000453342 533.4692445 2.2016907 2.0230478 2.1654208 9.5311029 11.2246821 11.7648175 COX6C 1.8119455 0.04958755 0.000846506 476.7862499 1.8744435 2.0230478 4.4498938 10.7716423 10.9430782 12.193477 RPLP1 2.095830752 0.04958755 0.000276819 435.5638137 6.5212096 6.0726357 6.5278107 14.3822043 15.7350278 15.2879499 PLAC9 2.087657395 0.04958755 0.000292867 417.2461993 1.8744435 2.406905 2.1654208 10.8701759 10.1377987 11.3236165 S100A4 1.898294036 0.04958755 0.000581722 403.7127825 2.993831 2.0230478 2.1654208 9.6949272 10.8915463 11.6510165 CRIP1 1.94320544 0.04958755 0.000509508 331.8700773 1.8744435 2.0230478 2.1654208 10.2489183 10.3046864 13.3062766 TRMT5 2.00878041 0.04958755 0.000397176 313.6729166 2.993831 2.406905 3.3243747 11.6174919 10.9138572 10.9475666 RPL5 1.820629375 0.04958755 0.000806387 312.0508774 4.6820765 4.9115166 6.4507011 12.9677139 13.2606973 13.4534914 GPR124 1.854126236 0.04958755 0.000726149 303.5484281 2.2016907 2.406905 3.9352215 11.488177 10.4474736 10.964382 MRFAP1 1.925871803 0.04958755 0.000525556 297.7890169 1.8744435 2.0230478 2.1654208 10.2950545 9.2452562 10.3835676 NGFRAP1 2.016446906 0.04958755 0.000381128 275.0852243 2.2016907 2.8096013 2.1654208 10.2042831 10.5428155 10.9133361 EEF1B2 1.821363767 0.04958755 0.000798363 256.1184813 5.6586086 3.8720139 4.5083337 11.8726814 13.4982434 13.0949964 ID2B 2.05796395 0.04958755 0.000332986 254.1750195 1.8744435 2.0230478 2.1654208 10.1550993 9.9150431 9.9011097 ID4 1.897124133 0.04958755 0.000589746 252.5713197 2.993831 2.0230478 2.1654208 9.921389 10.1587087 10.974378 CSN1S2AP 1.766559238 0.04958755 0.001006981 244.8191184 1.8744435 2.0230478 2.1654208 8.7595777 9.9586202 11.5499195 NDUFA12 1.679843789 0.04958755 0.001327931 221.5800857 1.8744435 2.0230478 2.1654208 8.1554584 10.0147482 9.8147322 TPT1 1.872361385 0.04958755 0.000669983 218.8064975 7.3175786 7.5987767 8.3453359 15.3722884 15.9356836 15.1839282 FOS 1.759686731 0.04958755 0.001023028 212.2571788 7.9061745 8.3595375 9.4853018 16.6082294 16.2213996 15.635844 IGFBP7 1.65560679 0.04958755 0.001424216 209.3287664 7.3921232 5.1957839 6.7042855 12.9054107 14.6094119 14.8693167 NDUFB4 1.493463501 0.04958755 0.002281152 208.7156419 5.3044627 2.406905 2.1654208 10.0513961 10.1122999 11.5764126 TMEM50A 1.520345167 0.04958755 0.002112653 201.0725579 4.6394091 2.0230478 2.1654208 10.3937635 9.8802157 9.6746202 BRP44L 1.814686728 0.04958755 0.000838482 196.9348643 1.8744435 2.0230478 2.3793449 8.9446225 10.0009196 9.6498858 ATP5C1 1.66930315 0.04958755 0.001360026 193.2139252 2.2016907 3.8720139 2.1654208 9.8991573 9.7594761 10.3326709 C1orf54 1.847285377 0.04958755 0.000734173 187.3542647 1.8744435 2.0230478 2.1654208 8.9732809 9.5726728 9.9011097 SCP2 1.647703974 0.04958755 0.001464334 186.263745 1.8744435 3.7709946 2.1654208 9.7946438 10.4061014 9.4156466 LMOD1 1.6465569 0.04958755 0.001472358 182.7950339 2.2016907 3.360637 2.1654208 8.6922175 10.6322453 10.8747201 VKORC1 1.81935768 0.04958755 0.000814411 180.0144181 2.2016907 2.0230478 2.1654208 10.515675 9.6573895 9.0502468 COX5B 1.577302487 0.04958755 0.001807751 178.3216194 4.2098819 2.406905 2.3793449 9.4920255 9.8852428 11.7298405 NEXN 1.628041721 0.04958755 0.001560619 171.2147535 1.8744435 2.8096013 2.1654208 8.5941417 9.585084 11.7376868 CAMLG 1.584433083 0.04958755 0.001767632 170.8974041 1.8744435 2.8096013 3.7641245 9.6378909 9.2914302 11.346887 ZCRB1 0.730109439 0.122332357 0.048180213 170.4798371 1.8744435 2.0230478 2.3793449 9.4365051 1.2054667 10.1565715 NSA2 1.665392749 0.04958755 0.001368049 170.1783538 3.0245043 4.3899364 4.2859964 10.6789908 10.8013455 11.8008401 FRZB 1.680291136 0.04958755 0.001319907 164.6148715 1.8744435 2.0230478 2.1654208 8.3206874 10.5364387 9.3859987 LUM 1.325246537 0.04958755 0.003685309 162.8753855 4.815804 4.3899364 5.9741452 14.898528 12.1634288 9.5102912 NUDT4P1 1.50381325 0.04958755 0.002184867 161.4407011 1.8744435 2.0230478 3.9083598 8.4987997 9.6515005 11.2432203 FAM83A 1.087975532 0.051099543 0.007900185 157.7790835 1.8744435 2.0230478 2.1654208 4.5400907 10.2036711 9.32481 GAS5 1.65829574 0.04958755 0.001384097 154.2221872 5.2636993 4.8304956 5.7236017 11.5103468 13.0980966 12.5325658 SH3BGRL 1.687732365 0.04958755 0.001287812 153.3767099 2.993831 3.7709946 3.9083598 10.2547666 10.4095948 11.5742234 HTRA1 1.68985596 0.04958755 0.001271764 153.1310862 2.993831 2.8096013 3.9083598 11.1669832 9.7758097 10.4708877 EIF3E 1.729612843 0.04958755 0.001111289 152.7662557 4.815804 4.9115166 3.9352215 12.1666987 11.3390176 11.6777725 HMGB1 1.786208332 0.04958755 0.000926743 151.9266336 3.3509967 3.7709946 3.9083598 10.4458174 11.0182256 11.209764 NDUFB9 1.724643617 0.04958755 0.001135361 150.4087851 3.0245043 2.406905 2.1654208 9.2961016 9.63965 10.8240285 ID2 1.858037615 0.04958755 0.000718126 147.0157127 1.8744435 2.0230478 2.1654208 9.1086088 9.3652474 9.1594204 RPS8 1.672940289 0.04958755 0.001352002 143.9921462 7.3553323 8.1702751 8.5253933 14.4062143 15.6952396 15.4187663 NPM1 1.697940181 0.04958755 0.001231646 135.1248514 4.2634629 5.297868 5.5715986 12.0878069 12.6497478 11.8702944 APEX1 1.724583928 0.04958755 0.001143384 130.4360676 2.2016907 2.0230478 2.1654208 9.0559909 10.8890459 9.0502468 RPL23P8 1.762733974 0.04958755 0.001015004 130.2506523 8.2244688 8.4079855 8.7104835 15.2496156 15.3777432 15.9830695 SNX3 1.588710112 0.04958755 0.001751585 128.5751992 4.815804 3.360637 3.7641245 10.7797775 10.3671056 10.892401 HSPA1B 1.349532351 0.04958755 0.003436572 127.4012481 6.0548278 7.4768994 10.290431 14.470135 15.6075614 14.2615737 HSPA6 1.257105041 0.04958755 0.004503731 124.381701 1.8744435 3.7709946 6.2829045 11.2673077 12.0130894 8.833074 GADD45A 1.482436267 0.04958755 0.002377437 122.9810319 2.2016907 4.4133226 3.3243747 10.3175808 10.2666667 9.2717591 SPARCL1 1.695383389 0.04958755 0.001247693 122.6627149 5.8972917 4.9115166 5.2176156 12.3396908 12.1561685 12.1441484 SHFM1 1.625357334 0.04958755 0.001568643 121.4047016 1.8744435 2.406905 2.1654208 9.0891013 8.492491 11.1135456 SDHD 1.553693036 0.04958755 0.001952178 118.9246556 1.8744435 2.8096013 2.1654208 9.7035053 8.0663803 9.1710561 TRIAP1 1.363652009 0.04958755 0.003300168 117.2277551 1.8744435 2.8096013 2.9956812 10.3007191 7.1932904 9.6827716 CYC1 1.556023812 0.04958755 0.001936131 115.8145008 1.8744435 3.360637 2.9956812 8.7346847 9.9297155 9.8513533 RPL37 1.623480945 0.04958755 0.001592714 113.8051711 7.4971815 8.5953745 8.7350882 14.5925156 15.5655105 15.3421906 CSDA 1.653217538 0.04958755 0.001432239 113.1484488 4.2634629 2.406905 3.9352215 10.7572945 10.4975743 10.8604176 C3orf58 0.773325102 0.102731018 0.036751184 111.3829314 3.3509967 2.406905 2.9956812 9.8991573 10.150381 2.9363609 RPL22L1 1.542645885 0.04958755 0.002008345 110.5620909 3.0245043 2.0230478 2.1654208 9.4969685 9.8132173 8.1057709 CRIM1 1.452682565 0.04958755 0.002594078 110.0472041 2.993831 4.3513152 2.3793449 8.9446225 9.7758097 11.2349287 TSPYL4 1.612298722 0.04958755 0.001640857 109.7535432 3.0245043 2.0230478 2.9956812 9.1717924 9.802628 9.1358635 ESD 1.628935008 0.04958755 0.001544572 108.3953599 2.993831 2.0230478 3.7641245 9.6644958 9.7539902 10.4708877 FAM162A 1.534570789 0.04958755 0.002024392 107.2637724 3.0245043 2.0230478 2.1654208 9.1021356 8.1852726 9.7695234 VPS29 1.210057074 0.04976927 0.00521945 107.242504 1.8744435 2.0230478 2.1654208 8.7677808 5.6724615 9.6076956 LMBRD1 1.588188941 0.04958755 0.001759608 102.2988435 1.8744435 2.8096013 2.3793449 9.0559909 8.3971729 9.62472 C2orf40 1.25502942 0.04958755 0.004551874 100.0050568 4.2098819 6.4662577 3.9083598 9.042531 12.0792909 13.1101869 SNCA 1.514903647 0.04958755 0.002136725 99.91921443 1.8744435 3.3213504 2.1654208 8.8081111 8.5186068 9.5194229 HSPA2 1.624362497 0.04958755 0.001584691 98.81739776 2.2016907 2.0230478 2.1654208 8.792114 9.3866756 8.1996456 RCN2 1.570698655 0.04958755 0.001855893 98.53634008 1.8744435 2.0230478 2.1654208 9.7865924 7.9173057 8.6456318 MARCH7 1.573906313 0.04958755 0.001831822 96.59859584 1.8744435 2.0230478 2.9956812 9.0221027 8.9985279 8.4683738 PDE5A 1.392211273 0.04958755 0.00306748 96.29592213 3.3509967 2.0230478 2.9956812 7.7378191 9.585084 10.7866977 GAS1 1.425320668 0.04958755 0.002842815 92.84004774 3.8197323 2.0230478 2.9956812 11.211266 9.1975554 8.5597232 CENPH 1.479198037 0.04958755 0.002433603 90.806377 4.7435639 3.7709946 2.1654208 9.8342407 11.2482856 10.1089703 TMEM66 1.577099619 0.04958755 0.001815775 90.72049693 3.8197323 3.7709946 4.5083337 11.4273358 10.2743512 10.2906199 LETMD1 1.607427252 0.04958755 0.001664928 90.23148577 1.8744435 2.0230478 2.1654208 8.0915413 8.5186068 9.2717591 LOC572558 1.257747329 0.04958755 0.004495707 90.23148577 1.8744435 2.0230478 2.1654208 6.0805901 8.5186068 9.32481 LGALS3 1.549891724 0.04958755 0.001968226 90.16385704 4.963444 4.9115166 5.7236017 12.5593915 11.2715091 11.4579213 ARL5B 1.390198804 0.04958755 0.003083527 89.53147488 1.8744435 2.0230478 4.7244061 10.0680992 11.2087291 8.2662493 C9orf16 1.460560392 0.04958755 0.002529888 89.4839902 3.0245043 4.7507076 3.3243747 11.0954589 9.8079324 9.6989376 TXN 1.657574944 0.04958755 0.001400144 89.10525649 4.7435639 4.3899364 4.7244061 11.0440392 10.9550811 11.2210025 KLHL20 1.458277395 0.04958755 0.002561983 88.28304195 1.8744435 2.0230478 2.3793449 9.8264078 7.4590463 8.4871122 SSBP2 1.567587513 0.04958755 0.001863917 86.87340126 2.2016907 2.0230478 2.3793449 8.2046286 8.6425333 9.9957527 OTUD1 1.387472669 0.04958755 0.003107598 86.31581609 3.3509967 2.0230478 4.2859964 9.7825497 8.6306088 10.2852763 FRA10AC1 1.529397684 0.04958755 0.002064511 86.18477383 3.0245043 2.0230478 2.1654208 8.5848861 8.4524089 9.5991074 CPE 1.411164363 0.04958755 0.002963171 86.13910109 5.6586086 4.3513152 6.0316576 13.1100097 10.7799116 11.6447709 NDUFS4 1.32764682 0.04958755 0.003637166 86.00454975 4.2098819 2.0230478 2.1654208 8.8473445 8.9320699 8.4493889 RHOBTB2 1.299050496 0.04958755 0.003934045 86.00454975 1.8744435 2.0230478 2.1654208 6.3662802 9.1975554 8.4493889 HOXD8 1.256597584 0.04958755 0.004519779 86.00454975 1.8744435 2.0230478 2.3793449 6.2304884 8.9609276 8.4493889 ATPIF1 1.520079762 0.04958755 0.002120677 85.457625 3.0245043 2.0230478 2.3793449 9.4416416 8.2645713 8.8905079 EXTL2 1.657927005 0.04958755 0.001392121 85.17722749 1.8744435 2.0230478 2.1654208 8.2868394 8.5694617 8.4683738 TGFBI 1.431778936 0.04958755 0.002794672 84.5847424 6.3818471 5.1480825 6.7692467 11.5888403 12.5511867 13.1715722 C8orf59 1.527350527 0.04958755 0.002088582 81.75696807 3.8399484 3.3213504 2.1654208 9.2789856 10.0819703 9.6746202 DDOST 1.359787432 0.04958755 0.003348311 81.75222065 4.6394091 3.3213504 2.1654208 10.5278012 8.5186068 10.2959438 CPNE3 1.269435444 0.04958755 0.004311161 81.17688147 4.309025 3.8720139 2.1654208 8.6661239 8.8104958 10.652022 LDB3 1.222646743 0.049622329 0.005025275 81.05015516 3.0245043 5.297868 2.1654208 8.7093547 9.3652474 9.8072951 IKBIP 1.306551712 0.04958755 0.003869855 80.2856462 4.309025 2.0230478 2.1654208 8.3860905 8.492491 9.62472 PA2G4 1.560754558 0.04958755 0.00191206 78.66443444 1.8744435 2.0230478 2.1654208 8.3206874 7.89754 9.0502468 NNMT 1.272026986 0.04958755 0.004263019 77.61720445 4.6394091 5.4346801 3.7641245 11.7129846 9.0169669 11.0329417 RAB13 1.263967871 0.04958755 0.004407446 77.58775101 5.4911209 3.3213504 2.9956812 10.2893675 9.3214118 9.5991074 COX411 1.534205737 0.04958755 0.002048463 77.5690528 5.3162271 4.8079702 5.7236017 11.2157704 11.5936364 11.7298405 MFF 1.543301563 0.04958755 0.002000321 77.33312988 3.0245043 2.0230478 3.3243747 8.90798 9.5973894 9.2932141 ARID4A 1.357625431 0.04958755 0.003372382 77.21566241 4.309025 2.406905 3.9083598 10.6459942 8.6777266 9.9150162 TSPAN8 1.592514075 0.04958755 0.001727513 76.69548921 1.8744435 2.0230478 2.1654208 8.1428995 8.1355133 8.6948242 NFYC 1.18893642 0.049809046 0.005525957 76.64975075 3.0245043 2.406905 3.9352215 9.2847135 6.9843361 10.4614424 PSMA5 1.318513484 0.04958755 0.003741475 76.47272106 4.2634629 2.0230478 2.1654208 9.2499997 8.2799211 8.8476482 PDGFD 1.594099673 0.04958755 0.00171949 75.74114718 1.8744435 2.0230478 2.1654208 8.1174489 8.618585 8.1534715 RPL7 1.3766417 0.04958755 0.00319586 75.71781413 7.7305591 8.0774702 8.1395596 12.8629666 14.320031 14.4021203 GUCY1A3 1.204465435 0.049809046 0.005317339 75.23008478 3.8399484 2.8096013 2.1654208 6.7105675 10.0731862 9.9492072 TUBA1B 1.495452473 0.04958755 0.002257081 74.96786098 5.8972917 6.0361098 5.5929159 11.3651676 12.2643101 12.1278212 FBXL5 1.492505724 0.04958755 0.002289176 74.82594796 2.993831 2.0230478 2.1654208 9.1779611 8.2799211 8.3908876 WBP5 1.479710635 0.04958755 0.002409532 74.31002586 2.993831 4.7507076 3.9352215 10.3777739 10.1036991 10.1507065 NCSTN 1.287900928 0.04958755 0.004054401 74.01416522 4.2634629 2.0230478 2.9956812 10.6548673 7.89754 9.2054107 CDKN1B 1.258808243 0.04958755 0.004487684 73.91627559 3.0245043 2.8096013 3.3243747 9.2323245 9.63965 7.277042 EIF2B1 1.619324424 0.04958755 0.001608762 73.79376795 1.8744435 2.0230478 2.1654208 8.2166637 8.2014848 8.3708479 CSRP2 1.277513525 0.04958755 0.004150686 73.52784755 2.993831 2.0230478 2.1654208 6.7770801 8.6306088 9.1940499 MYEOV2 1.59222937 0.04958755 0.001735537 73.47300304 1.8744435 2.0230478 2.1654208 8.4486569 8.0305306 8.2221901 MDP1 1.353328829 0.04958755 0.003412501 73.47300304 1.8744435 2.0230478 2.1654208 6.7770801 8.5186068 8.2221901 AKR1D1 1.451592365 0.04958755 0.002626173 73.33292309 2.993831 3.7709946 3.9352215 9.1902202 10.5332397 9.5011013 SUMO1P3 1.509272512 0.04958755 0.00216882 73.3088369 3.0245043 2.0230478 2.9956812 9.2204195 8.7233541 8.7579092 OSGEP 1.181992672 0.049897122 0.005702479 71.42190958 2.2016907 2.0230478 3.3243747 6.4501951 9.4826695 8.3908876 RAB6C 1.356873329 0.04958755 0.003380406 71.33648369 1.8744435 2.8096013 2.1654208 8.9661695 8.9609276 7.0438915 TUBA1A 1.522741496 0.04958755 0.00210463 70.82043701 4.963444 5.8096013 4.9444683 11.0905621 11.9316049 11.5610175 ZMYM6NB 1.27444784 0.04958755 0.004206852 70.7599515 4.2634629 2.0230478 2.1654208 8.167909 8.492491 9.1119156 SEPP1 1.438843966 0.04958755 0.002770601 69.7076022 4.2634629 4.7507076 5.2176156 12.5605724 10.8739517 10.2307226 SRP9 1.340519984 0.04958755 0.003508786 68.75018272 6.0082059 4.3513152 4.7244061 10.4886329 10.8276977 10.964382 TMEM173 1.410807276 0.04958755 0.002971195 67.89101196 2.2016907 3.3213504 2.3793449 8.2868394 8.3543123 10.2582573 SMARCD3 1.366321237 0.04958755 0.003268073 67.77696173 3.8399484 2.0230478 2.1654208 8.7093547 9.5411694 8.1057709 TMEM14C 1.440060555 0.04958755 0.002738506 67.42583117 3.8399484 2.406905 2.9956812 8.9873994 9.0709107 9.2278676 HNRPDL 1.143832093 0.050004604 0.006502447 67.09779763 5.3354128 5.6616851 5.7236017 11.7298786 12.0073369 9.0875635 DKK3 1.021508686 0.053385633 0.009912541 66.06024177 2.2016907 3.360637 2.3793449 5.3405168 8.4250552 10.0784017 LSM6 1.474758131 0.04958755 0.002449651 65.53641157 1.8744435 2.406905 2.1654208 7.7210195 9.2530552 8.1996456 UBE2NL 1.300373059 0.04958755 0.003917997 65.24682953 1.8744435 3.3213504 3.7641245 8.3094927 9.7919604 8.4106527 SNX17 1.37096864 0.04958755 0.003244002 65.18289308 3.8399484 2.8096013 2.9956812 9.0221027 8.4111814 10.3785579 SYNPO2 1.088683463 0.051099543 0.007876113 65.04402637 6.0999914 3.7709946 3.9352215 8.0517861 10.4677231 12.123336 EIF3M 1.167538131 0.04991757 0.006054722 65.02830438 1.8744435 4.8304956 2.3793449 8.5376958 9.2989842 7.8974394 ARPC2 1.338497886 0.04958755 0.003524834 64.94385735 5.2636993 3.8720139 3.3243747 10.3091746 10.7192716 9.3454959 MAGEB10 1.468276533 0.04958755 0.002497793 64.67962353 3.0245043 2.0230478 2.1654208 8.0382872 8.6892694 8.7108559 LOC401397 1.288154681 0.04958755 0.004046377 64.67962353 3.8399484 2.0230478 2.1654208 8.0382872 8.2951094 8.5238744 SFRP2 1.102664421 0.050647945 0.007502207 64.43314203 3.8399484 2.8096013 4.7244061 11.9249666 9.8496795 7.0438915 CCNI 1.412509957 0.04958755 0.0029391 64.1749969 7.2590288 5.1480825 6.4897707 13.2138577 12.0715935 12.4937102 CPZ 1.374128252 0.04958755 0.003219931 63.71532184 2.993831 2.8096013 3.9352215 9.3407758 8.3397377 9.92879 F10 1.26110697 0.04958755 0.004439541 63.21189527 2.2016907 4.3513152 3.3243747 7.8958605 9.3064989 11.1344986 PPP1CA 1.297655189 0.04958755 0.003950092 62.71417303 3.8399484 2.0230478 2.1654208 8.3317959 7.9937674 8.7423946 C4orf43 1.471272756 0.04958755 0.002473722 62.6869192 2.2016907 2.0230478 2.1654208 7.6158948 8.1355133 8.9725869 PLRG1 1.349951005 0.04958755 0.003428549 62.56072818 2.2016907 3.7709946 2.3793449 8.6033384 8.1688761 9.0375903 PTP4A3 1.04157703 0.052218844 0.009273851 62.25169979 4.2098819 5.4346801 3.9083598 7.335969 11.3947214 10.7522537 BPHL 1.447922215 0.04958755 0.002650245 62.2475057 1.8744435 2.0230478 2.1654208 7.9829919 9.9869572 7.6203219 RNF130 1.247274884 0.04958755 0.004648159 62.06909417 2.993831 2.406905 4.2859964 10.1425368 7.4040744 10.2417996 C10orf116 1.107755293 0.050567091 0.007332103 61.81852322 6.0082059 7.1970971 6.9199049 9.906606 12.8698722 14.2454979 PABPC1 1.497341339 0.04958755 0.002224986 61.79922223 8.3134756 8.2991672 8.2910567 13.8826068 14.248684 14.6961651 YBX1 1.439984097 0.04958755 0.00274653 61.71215431 5.0569476 4.7507076 5.3892653 10.4560066 11.0044304 11.671642 TMEM200B 1.243826297 0.04958755 0.004688277 61.4443822 1.8744435 2.0230478 3.9083598 8.0109044 7.8156527 8.577319 SCARB2 1.271590944 0.04958755 0.004271042 61.13940004 4.963444 4.4133226 4.5083337 11.1545241 9.0531526 10.4423642 COMMD3 1.256251288 0.04958755 0.004527802 61.09554124 1.8744435 2.0230478 2.1654208 6.2771857 7.956043 8.6948242 TTC37 1.413153818 0.04958755 0.002923052 61.08895858 3.3509967 3.3213504 2.3793449 9.1779611 9.2838364 8.350526 LOC100130992 0.954763991 0.058459296 0.013046618 60.66146213 1.8744435 2.0230478 2.9956812 4.5400907 8.2014848 8.9183896 GTF3A 1.494946165 0.04958755 0.002265105 60.48710739 1.8744435 2.0230478 2.1654208 7.5790795 8.0839766 8.0813159 C13orf15 1.302997066 0.04958755 0.003877879 59.80779534 3.8399484 3.7709946 3.3243747 9.6732562 9.7812134 8.2221901 NUP133 1.354719271 0.04958755 0.00338843 59.75383871 2.2016907 2.0230478 2.1654208 6.9599943 8.0663803 8.6456318 DLC1 1.239666427 0.04958755 0.004720372 59.10560221 1.8744435 2.8096013 4.2859964 11.1164882 7.7062919 8.6948242 KAZALD1 1.164353572 0.04991757 0.006102864 58.89126673 1.8744435 2.0230478 4.7549172 7.7544253 8.5314896 8.985824 AGR2 1.36474802 0.04958755 0.003284121 57.99132181 1.8744435 2.0230478 2.1654208 7.8808129 6.9463683 8.6118796 PPIG 1.086854253 0.051099543 0.007948327 57.9386355 5.7794294 4.8079702 4.5083337 11.6764143 8.3971729 10.664424 PDGFRL 1.273968839 0.04958755 0.0042229 57.9105084 1.8744435 2.0230478 3.7641245 9.6198778 7.7288372 7.925186 SUMF1 1.338681832 0.04958755 0.00351681 57.55403893 1.8744435 3.360637 2.1654208 9.0289443 8.0122661 7.8108476 MYH11 1.228827781 0.049622329 0.004920966 57.27924846 2.993831 4.3899364 2.1654208 8.5472581 10.7471516 8.0053615 CHTOP 1.238000448 0.04958755 0.004752467 57.11515586 4.815804 2.0230478 2.9956812 8.4281014 8.831483 10.0722095 APOF 1.154242557 0.04991757 0.006335553 56.38520863 1.8744435 2.0230478 2.1654208 5.7241063 8.1688761 7.8402926 DNAJC1 1.208497727 0.04976927 0.005259568 56.09338511 1.8744435 2.406905 2.9956812 8.2166637 6.5504789 8.9592273 RAB9A 1.146298538 0.049952273 0.006446281 56.09338511 3.3509967 2.406905 2.1654208 8.2166637 6.4455364 9.2609108 TMEM9 1.336139445 0.04958755 0.003556929 55.96704725 2.2016907 3.3213504 3.3243747 9.1278561 7.7728978 10.652022 ISCU 1.121704249 0.050341156 0.00693252 55.74772078 4.963444 3.7709946 4.5083337 10.3091746 7.9173057 11.016911 CIR1 1.391702504 0.04958755 0.003075503 55.60823767 3.3509967 3.3213504 3.7641245 9.9648504 9.1482234 8.6786124 PCBP1 1.469786481 0.04958755 0.002481746 55.45771505 6.0999914 5.4876732 6.0560619 11.5237292 11.7765588 11.8933076 SCOC 1.187092333 0.049875978 0.005582123 55.16140473 2.2016907 2.406905 2.3793449 8.1924923 6.2722716 8.1767432 SERPINB1 1.363712477 0.04958755 0.003292145 54.1828797 2.2016907 3.360637 2.1654208 8.2404369 8.9609276 7.925186 ANGPT1 1.272721237 0.04958755 0.004246971 54.10692909 1.8744435 2.0230478 2.1654208 6.4501951 9.0260988 7.7807893 RRAD 1.182597163 0.049897122 0.005670384 53.9419662 5.0569476 2.8096013 4.7244061 8.2046286 10.4777423 11.4507791 TXNIP 1.272637775 0.04958755 0.004254995 52.94693365 6.7078705 4.7507076 6.564874 12.3547449 10.8013455 12.2913492 RPS20 1.373057483 0.04958755 0.003235978 52.86393774 8.2941654 8.5442716 8.4481275 13.4266559 14.1723395 14.6373499 FTO 1.213656157 0.049622329 0.005153655 51.24389687 5.3354128 2.8096013 2.9956812 8.4889095 10.1711108 9.6162329 TAF7 1.185041995 0.049897122 0.005614218 51.20170184 4.6820765 3.7709946 2.1654208 9.6107862 9.4491144 8.0564393 JPH4 1.300400867 0.04958755 0.003909974 51.1341912 3.0245043 2.0230478 2.1654208 7.0702087 8.7007207 8.3908876 SDPR 1.188535221 0.049809046 0.005533981 51.08655784 2.2016907 2.0230478 2.1654208 6.0269554 9.0351732 7.8402926 MINOS1 1.28631585 0.04958755 0.004070449 50.69951751 5.0569476 3.8720139 4.4498938 9.535914 9.5973894 10.8129303 ZNF32 1.141081302 0.050038461 0.006558613 50.65987046 4.6394091 3.8720139 2.1654208 7.4827092 9.5347853 10.3735309 PCOLCE 1.235550224 0.04958755 0.004808634 50.64708585 4.2098819 5.4346801 6.6010094 11.0970874 10.3562848 11.595968 PLS3 1.24253936 0.04958755 0.004696301 50.40470395 2.2016907 3.8720139 2.3793449 7.9107527 7.8571772 10.7050105 LSM3 1.112589744 0.050440463 0.007214956 50.40432222 5.3044627 2.8096013 3.3243747 8.5183788 8.9798503 9.0752315 NGRN 1.213165485 0.049622329 0.005169702 50.36193654 3.3509967 3.8720139 2.9956812 9.5262757 7.4857665 9.5011013 ZFP2 1.230649539 0.04958755 0.004880847 49.76530678 1.8744435 2.0230478 2.1654208 6.2304884 7.6601162 8.5056104 PFDN5 1.283686576 0.04958755 0.004102544 49.11269646 6.6175557 6.4291897 7.1568531 11.3932764 12.2604461 12.7748773 PSMA3 1.226333944 0.049622329 0.004961085 49.09072991 4.2634629 2.0230478 3.3243747 7.9254928 8.9417534 9.473175 NFIA 1.144851825 0.049952273 0.006478376 48.59003034 8.2039211 5.3406193 7.3175252 13.8065095 11.7340016 11.9107637 CC2D2B 1.390073999 0.04958755 0.003091551 48.26304389 1.8744435 2.0230478 2.1654208 7.6158948 7.2567201 8.7267115 HSDL2 0.972842488 0.056901344 0.012062104 48.02597265 4.6394091 2.0230478 2.3793449 5.5826351 8.872563 10.225152 LPCAT4 1.179623371 0.049897122 0.005806788 47.87739864 1.8744435 3.3213504 2.3793449 6.5294995 8.9026233 8.3908876 ITFG1 1.223162307 0.049622329 0.005009227 47.69275331 3.8399484 2.0230478 2.1654208 8.5848861 7.0925914 9.4156466 MMGT1 1.192755838 0.049809046 0.005477814 47.34622678 4.6820765 3.7709946 2.1654208 9.7373165 9.3361721 8.1298183 EPHX1 1.235308241 0.04958755 0.004816657 47.13234941 4.2098819 4.4133226 4.9444683 9.9719683 8.9026233 11.2432203 PNRC1 1.223343852 0.049622329 0.005001204 46.9937726 8.1619262 6.1390574 8.0377511 12.9334843 13.7163239 12.3019721 CCNG1 1.179877657 0.049897122 0.005790741 46.95821723 2.2016907 4.7507076 2.1654208 9.0152285 9.0884529 7.7187266 ATP5F1 1.239248843 0.04958755 0.004728396 46.94223549 3.0245043 2.8096013 3.9352215 9.9612782 7.8365643 8.577319 TOP1P1 1.331001422 0.04958755 0.003605071 46.20712428 2.993831 3.3213504 3.9083598 8.8855392 9.0351732 8.5238744 H6PD 1.064669082 0.051378258 0.008507582 45.82600305 6.5861495 3.360637 2.3793449 11.0098654 10.507389 7.8974394 RCAN2 1.080495704 0.051255379 0.008116023 45.8028459 5.7445127 2.406905 4.7244061 8.6124767 11.2618781 9.2825265 PROS1 1.251466364 0.04958755 0.004591992 45.04456776 2.993831 2.406905 3.9352215 8.1045532 8.6064601 8.4871122 MEA1 1.320226275 0.04958755 0.003717404 44.98683606 3.3509967 2.8096013 2.9956812 8.0784109 10.5268203 8.4871122 CKS1B 1.275690462 0.04958755 0.004166734 44.90963177 3.0245043 2.0230478 3.3243747 9.1902202 7.5120008 8.4301508 UQCRQ 1.17123908 0.04991757 0.005966461 44.424703 5.8565586 4.3513152 3.7641245 9.6600956 9.2374148 11.9518161 RBMXL1 1.238370018 0.04958755 0.004744444 44.36064291 4.963444 2.406905 3.9083598 9.8991573 9.3795682 8.9045161 ETV1 1.395577091 0.04958755 0.003027361 43.85511891 2.2016907 2.0230478 2.3793449 7.6339561 8.0663803 7.4777211 GEM 1.12529579 0.050330336 0.006876354 43.52923052 5.3044627 6.1390574 7.8096632 11.9585009 12.0988978 10.7483753 HAS2 1.053333045 0.051900312 0.00892241 43.50277077 1.8744435 2.8096013 5.018694 8.7759375 7.3174789 8.8034763 TRA2B 1.254309489 0.04958755 0.004567921 43.49411589 5.7445127 4.7365865 5.018694 9.8342407 11.1925978 10.4614424 BAG3 1.16868153 0.04991757 0.006014603 43.44352174 5.7445127 6.9314777 7.6635078 11.4757116 13.104577 11.6067187 ITPKB 1.251400122 0.04958755 0.004600016 43.24524336 2.993831 2.0230478 2.9956812 7.6694143 7.5879581 8.4301508 FILIP1L 1.210814628 0.049694878 0.005201797 43.11079458 5.2636993 3.3213504 4.4498938 8.7513276 10.3885066 10.3785579 PLSCR4 1.173276782 0.04991757 0.005918318 42.84224996 3.8399484 3.3213504 4.5083337 10.9695379 7.956043 9.2609108 DPYD 1.13183715 0.050131358 0.006717484 42.60573396 1.8744435 2.0230478 4.4498938 8.4072489 7.2874192 8.5419101 USMG5 1.117965601 0.050341156 0.0070609 42.34928863 4.6820765 5.297868 2.3793449 8.1428995 10.0863423 10.6353184 SNRNP27 1.205939776 0.04976927 0.005299687 41.87462177 3.8399484 3.3213504 2.1654208 8.7093547 7.5879581 8.9725869 CCDC71L 1.207572491 0.04976927 0.00528364 41.84107785 4.815804 5.297868 4.2859964 10.7838279 9.0971447 10.2026521 PHF17 1.19477139 0.049809046 0.005437696 41.76391558 6.6482929 4.9115166 6.2829045 10.2193155 12.032478 11.8541443 JTB 1.277581166 0.04958755 0.004142662 41.60696211 4.815804 3.8720139 3.9352215 9.21443 9.3139746 11.0424753 STXBP3 1.314375881 0.04958755 0.003781594 41.57502364 1.8744435 2.0230478 2.1654208 7.400693 8.5314896 6.8834842 MCM3 0.90652013 0.065320795 0.016626013 41.42259025 1.8744435 3.3213504 2.1654208 4.5400907 7.5377667 9.8294924 KRT18 1.188466971 0.049809046 0.005542004 41.36811838 1.8744435 3.8720139 2.1654208 7.244891 8.7675828 8.0053615 NDUFAB1 1.134749868 0.050038461 0.006670946 41.04899075 1.8744435 2.8096013 2.1654208 6.0269554 8.1688761 7.925186 CLU 1.220192652 0.049622329 0.005049346 41.0003459 4.309025 6.0441977 4.7244061 9.9896111 10.0819703 11.0007002 RPP40 0.793104195 0.094990031 0.03240873 40.86333087 1.8744435 2.0230478 2.1654208 3.1012538 7.3757827 8.3708479 PARK7 1.183245174 0.049897122 0.005654337 40.73945076 4.963444 4.3899364 2.3793449 9.5691497 8.5186068 10.3117986 TMEM14A 1.154126905 0.04991757 0.006351601 39.51249258 1.8744435 3.7709946 2.9956812 7.6339561 7.5120008 9.0752315 NTRK2 1.093741072 0.050952718 0.007725267 39.38100766 2.2016907 4.7507076 2.9956812 7.335969 8.2951094 11.0265508 EIF4E 1.293115393 0.04958755 0.003998235 39.1691643 5.7794294 6.1842483 6.0721689 11.3638154 11.7087024 10.7327567 CXCL14 1.127760708 0.050237584 0.006829816 39.15476934 4.309025 6.0924064 5.5929159 12.3140128 10.884032 9.1119156 DIMT1 1.116399801 0.050341156 0.007092995 38.70718979 1.8744435 3.360637 2.3793449 6.4088472 9.2056159 7.6538745 LOC100129316 0.891568891 0.067647212 0.018014122 38.60104563 1.8744435 2.0230478 2.9956812 4.1976103 8.1852726 8.2662493 PFDN1 1.105638493 0.050608213 0.007429993 38.53508315 1.8744435 2.0230478 2.1654208 7.2911484 5.5764175 8.3090028 SYBU 1.249210792 0.04958755 0.004624087 38.43560364 1.8744435 2.0230478 2.1654208 6.6046733 7.2874192 9.3454959 TMEM159 1.043832883 0.052218844 0.009209661 38.43560364 1.8744435 2.0230478 2.9956812 5.5826351 7.2874192 9.4918525 SDHB 0.975021932 0.056617715 0.011955388 38.43560364 1.8744435 2.0230478 2.1654208 4.8170878 7.2874192 7.4397554 PM20D2 1.093785567 0.050952718 0.007717243 38.30294505 1.8744435 3.8720139 2.3793449 6.6408414 9.1313973 7.7500915 TSPAN6 1.209016548 0.04976927 0.005235497 37.86890311 3.8197323 2.0230478 2.1654208 9.062674 6.9073747 8.9457427 CHMP2B 1.061990088 0.051493437 0.008611891 37.25049072 1.8744435 2.8096013 4.2859964 9.7205099 7.5377667 7.093631 RFK 1.244846221 0.04958755 0.004680254 37.22365586 1.8744435 3.3213504 2.1654208 8.4987997 7.0925914 8.0564393 MTDH 1.152706596 0.04991757 0.006359624 36.92006254 5.3044627 5.1480825 3.9352215 10.5107958 9.2530552 9.5904678 ARHGEF25 1.053500437 0.051888429 0.008899141 36.84905737 2.993831 2.8096013 3.9083598 8.2521782 6.6948447 9.1119156 CHPT1 1.25682892 0.04958755 0.004511755 36.73507144 4.2098819 3.360637 3.9352215 8.9732809 9.7262434 8.5597232 PRKG1 1.232993795 0.04958755 0.004824681 36.6506059 1.8744435 2.0230478 2.9956812 7.0702087 7.5120008 7.6538745 RERG 1.08336884 0.051255379 0.00804381 36.63688122 3.8399484 2.0230478 2.9956812 6.4903918 9.0351732 8.6118796 CCL21 0.903857128 0.065688432 0.016833026 36.19275114 5.2636993 3.3213504 3.7641245 6.2771857 8.9417534 12.2913492 CAT 1.110357196 0.050482841 0.00727032 36.08658372 4.6820765 2.8096013 3.9352215 7.9829919 8.65436 9.9080797 DDX1 1.09502981 0.050952718 0.007669101 35.8962651 4.815804 3.3213504 2.1654208 7.7708426 9.2762025 8.4871122 SRP14 1.070121757 0.051378258 0.008356736 35.60183646 5.2636993 2.406905 3.9352215 9.0891013 8.0122661 9.6076956 METTL9 1.045489091 0.052154186 0.00915189 35.46470088 4.2634629 2.0230478 2.1654208 7.3137327 6.8260777 9.6162329 C14orf2 1.167914156 0.04991757 0.006038674 35.27071303 4.6820765 4.3513152 2.3793449 9.8224753 8.3687411 9.3038231 SRGN 0.878735799 0.069997503 0.019411859 35.24933404 6.5861495 2.0230478 5.2252164 11.7256736 8.734539 7.9524091 SNRPE 1.217994037 0.049622329 0.005073417 35.19871284 3.8399484 2.0230478 2.1654208 8.6748743 7.1604986 8.7732587 VEZT 0.946979859 0.059314973 0.01353045 35.05722834 3.8197323 3.3213504 3.3243747 8.5183788 8.9513724 6.1659595 THOC7 1.190097301 0.049809046 0.005509909 34.90370026 4.2098819 3.3213504 2.1654208 7.9107527 8.4387969 9.33519 CDC14B 1.250934032 0.04958755 0.004616064 34.6288712 1.8744435 2.406905 2.1654208 6.988347 8.7456379 7.0438915 SACM1L 1.108018963 0.050567091 0.007324079 34.58421951 2.2016907 3.3213504 4.2859964 7.3137327 8.6425333 8.932131 HES1 1.114131182 0.050390282 0.007149162 34.4407878 6.8989234 4.8079702 5.2252164 9.9140164 11.5859378 10.6603018 TCEAL4 1.031032678 0.052917554 0.009632512 34.38493745 2.993831 3.3213504 4.2859964 10.2547666 8.4250552 6.8257955 NDUFA4 1.236006231 0.04958755 0.00480061 34.01899484 4.2634629 4.8304956 4.9444683 9.3517316 9.7703857 12.0792452 ADH1B 1.104534829 0.050647945 0.007478135 33.82051586 4.7435639 3.8720139 6.0721689 8.9518406 10.150381 10.8092119 IFT46 1.136970343 0.050038461 0.006622803 33.50987303 2.2016907 2.0230478 2.3793449 7.268205 8.2799211 6.069928 TTF1 1.049775849 0.051934328 0.009009067 33.35735192 2.993831 4.4133226 2.1654208 8.2166637 7.2253537 8.2877844 TPM1 1.066630038 0.051378258 0.008443392 33.17904161 5.2636993 6.1842483 3.3243747 8.8160436 10.3158996 11.1014343 SEPT7 1.06062609 0.051535817 0.00865201 33.12205037 6.3447976 4.8304956 4.7244061 9.1593751 9.8802157 11.924578 FAM110B 1.097027787 0.050892627 0.007630587 33.06334689 4.2098819 2.0230478 2.1654208 7.0702087 8.7007207 7.7807893 TMSB4X 1.259227779 0.04958755 0.004471636 32.83570884 8.9960085 8.6447292 9.4260873 14.3968235 14.0332022 13.8620403 GBP2 1.116751851 0.050341156 0.007084972 32.71044977 4.2634629 3.360637 4.7549172 8.6484622 9.7865969 8.4683738 ASNSD1 1.284977565 0.04958755 0.004086496 32.45539202 2.2016907 2.0230478 2.1654208 7.0434341 7.1604986 8.5947028 ATF6 1.056318328 0.051814299 0.008835754 32.14158087 5.7794294 4.7365865 2.3793449 9.7539295 9.7429554 8.6786124 RBM3 1.203181806 0.049809046 0.005325363 31.96968146 6.7367617 6.537655 5.018694 10.8947292 11.7353942 11.3621946 RPS24 1.218459898 0.049622329 0.005065394 31.81215456 8.3134756 7.885522 8.6164969 12.7649469 13.3049818 13.8789899 TRAPPC6B 1.222360087 0.049622329 0.005033299 31.60879706 2.2016907 2.0230478 2.1654208 7.147675 6.5504789 7.8108476 SKP1 1.225655084 0.049622329 0.004977132 31.48910377 4.6820765 4.8079702 3.3243747 9.4313502 9.2452562 9.784751 OS9 1.113179533 0.050440463 0.007190885 31.40162226 4.309025 5.1480825 5.2176156 11.0304667 10.1208497 8.6118796 AKAP9 1.079168649 0.051291304 0.008149723 31.32574214 3.8399484 3.360637 5.3892653 8.8081111 10.5835916 8.3299138 BOLA3 1.08392778 0.051255379 0.008011715 30.87780167 3.8399484 3.7709946 2.1654208 8.2404369 7.2567201 8.7884466 RHOB 1.19389932 0.049809046 0.005461767 30.81942645 9.0997518 8.0894025 8.050877 13.6197313 12.9966452 13.4747732 ZFYVE28 1.083584421 0.051255379 0.008035786 30.68131477 2.2016907 2.0230478 3.9083598 6.7105675 7.5879581 8.8476482 PPP3R1 1.17928695 0.049897122 0.005830859 30.66118368 4.2098819 4.3899364 3.9352215 9.4416416 9.1482234 8.4106527 HSP90AA1 1.111956607 0.050440463 0.007239028 30.00976133 8.3134756 8.5442716 9.4311157 13.6455578 14.3384757 12.7440469 SOD3 0.8413111 0.078969245 0.023810479 29.97106828 6.8201191 4.3513152 8.6427428 9.4820885 11.7256177 11.7513159 SMOC2 1.011459622 0.054106764 0.01032095 29.86282523 4.7435639 4.3899364 6.0540376 10.1106434 8.3250145 10.9543163 CHMP5 1.068286689 0.051378258 0.008387226 29.11967163 4.6394091 3.3213504 4.4498938 8.4588258 8.1852726 10.3378421 BUD31 1.135809126 0.050038461 0.006646875 29.05869226 2.2016907 3.360637 3.3243747 6.9310735 8.1852726 8.9592273 ATF1 1.171785545 0.04991757 0.005950413 28.93126406 4.309025 3.360637 2.9956812 7.8502387 9.1229101 8.818351 KIAA0040 1.11379844 0.050440463 0.007174838 28.7898761 2.993831 4.4133226 5.2252164 8.5661948 9.2608123 9.8657454 UROD 1.019126456 0.053434625 0.009984755 28.76033974 5.2636993 3.3213504 2.3793449 8.7513276 7.2253537 10.0968205 OXA1L 1.196354418 0.049809046 0.005405601 28.67050844 3.3509967 3.7709946 3.9352215 8.1924923 8.4250552 8.833074 CHCHD5 1.017902709 0.053512074 0.010066597 28.62112774 4.2634629 3.360637 3.3243747 7.0702087 9.4147603 8.1996456 TADA3 1.118860945 0.050341156 0.007020782 28.61782399 3.8399484 3.8720139 2.1654208 8.0246608 7.8365643 8.7108559 ADCY3 1.005622578 0.054519995 0.01062505 28.47134779 6.0548278 4.9115166 4.5083337 8.5848861 9.7429554 11.0007002 BOD1L 1.251495541 0.04958755 0.004583969 28.4354758 4.6820765 4.8304956 4.2859964 9.5116965 9.4286003 9.5904678 RSF1 1.103321921 0.050647945 0.007494183 28.09592371 6.0082059 4.7365865 5.2252164 10.9371717 10.0375054 9.3658894 NUTF2 1.044201536 0.052196569 0.009192008 27.9983901 5.0569476 3.360637 2.3793449 8.167909 8.9798503 8.0311264 KDM3B 1.157265402 0.04991757 0.006255316 27.96292869 2.993831 2.8096013 3.3243747 8.0915413 7.1604986 8.1298183 ZNF22 1.135202924 0.050038461 0.006654898 27.91198177 4.6820765 2.8096013 2.9956812 9.3894343 7.6124139 9.0119393 PRSS23 0.858015062 0.07443975 0.021530129 27.90585885 5.3285264 2.8096013 3.9083598 10.2518454 6.2722716 8.7108559 MTRNR2L8 0.883344973 0.06911283 0.018893525 27.88554783 8.9840072 11.9710046 12.3604928 13.7854529 16.0492172 17.4110649 MAT2B 1.062231312 0.051493437 0.008603867 27.75067801 5.3354128 4.3513152 3.9352215 10.1298639 8.3543123 9.2054107 PHF20L1 1.020552807 0.053420513 0.009944636 27.72767982 3.3509967 4.3899364 2.3793449 7.1725999 8.1522912 8.4106527 GRIP2 1.118420778 0.050341156 0.007044853 27.62692888 2.993831 2.8096013 2.3793449 7.5976045 6.6002221 8.8763623 ANAPC4 1.207263617 0.04976927 0.005291663 27.59191082 1.8744435 2.0230478 2.1654208 6.8092213 6.6483084 9.1594204 CAMK2N1 1.108563382 0.050567091 0.007316056 27.4197623 5.2636993 3.360637 5.5715986 10.1519689 9.062059 10.0408434 CKLF 0.877062992 0.070409075 0.019676643 27.28909407 2.2016907 2.0230478 3.9083598 4.9379926 7.7510357 8.6786124 CCDC23 0.977973225 0.056452334 0.011848672 27.14670171 4.2098819 2.0230478 2.1654208 7.5790795 6.0753543 8.9725869 RGL1 1.08762538 0.051099543 0.007908208 27.0409702 4.309025 3.7709946 2.9956812 8.5280696 9.3580333 7.550782 MAGEH1 1.100456639 0.050801344 0.007550349 26.98429144 5.2636993 2.0230478 3.9352215 9.6556819 8.6892694 8.577319 ABHD14B 0.988655221 0.055891005 0.0113512 26.92308403 5.3044627 3.3213504 5.2252164 7.8031272 10.1669886 9.9759882 MGC23270 1.100364081 0.050801344 0.007558373 26.65141881 3.3509967 2.406905 2.1654208 6.9015613 7.0213307 8.2662493 DBI 1.05073765 0.051900312 0.0089866 26.56643051 4.7435639 4.3899364 4.2859964 9.1214689 8.0305306 9.7307362 SEPT2 1.066092671 0.051378258 0.008467464 26.52132722 6.7650859 4.7365865 4.5083337 10.9924701 9.2374148 10.6561678 TENC1 1.052737588 0.051900312 0.008938458 26.49070248 3.3509967 2.406905 3.9352215 8.0784109 9.9248413 6.7657063 DCN 1.095932971 0.050930656 0.007653053 26.32546136 8.6910467 8.181467 9.3748148 15.5515758 13.4094336 12.6823704 FKBP3 1.158907362 0.04991757 0.006223221 26.27071633 3.3509967 3.8720139 2.1654208 8.3206874 8.0663803 7.8691489 PPP1CC 1.006896922 0.054519995 0.010592955 26.23121993 5.0569476 6.0726357 5.6099449 10.3231579 8.8210275 11.2569347 DNAJC19 0.99185007 0.055641947 0.011190725 26.2149345 5.3285264 3.3213504 2.1654208 7.7378191 7.7728978 10.0408434 H3F3C 1.101892388 0.05069779 0.007518254 26.20779302 7.5469748 6.0441977 6.8006628 12.0121399 12.0392592 10.7561217 SMARCA5 1.15158858 0.04991757 0.006383696 26.18030923 4.6820765 4.3513152 3.9352215 9.0956332 9.1143726 8.6456318 CSTF2T 1.128249261 0.050237584 0.006821793 26.14278261 3.0245043 2.406905 2.9956812 7.704022 6.7836452 8.2443879 OSBPL8 0.911676464 0.064396246 0.016130948 26.11251738 5.3162271 4.3513152 4.4498938 10.0412806 9.1565634 7.4397554 NR2F1 1.114643822 0.050390282 0.007133114 26.0353434 4.7435639 2.8096013 3.3243747 9.4209849 7.5120008 9.3454959 SSPN 0.965854952 0.057385588 0.012525074 26.02744303 3.8399484 2.406905 4.5083337 9.4157741 6.6483084 8.5419101 API5 0.997656928 0.055362341 0.011026238 25.86863709 1.8744435 2.406905 4.7549172 6.5675757 8.0305306 9.1358635 TRMT112 1.069532789 0.051378258 0.008372783 25.8642226 6.8989234 6.1842483 5.5929159 10.5682844 10.2858018 11.7532525 APPL2 1.141669697 0.050038461 0.00655059 25.60636104 3.8399484 4.3513152 2.1654208 8.5183788 8.3101394 8.6786124 MRPL24 0.976133088 0.056551597 0.011916072 25.49985287 4.6820765 3.3213504 2.1654208 7.3794393 7.9937674 8.0053615 ESYT2 1.127210629 0.050237584 0.00683784 25.41170312 3.3509967 3.7709946 4.4498938 8.4384157 8.5314896 8.3908876 HSP90B1 1.047493482 0.052136699 0.009113376 25.12316303 6.8201191 4.8079702 5.5446534 10.8490686 10.1955997 9.9559492 NUCB2 0.857158159 0.07471249 0.021641659 25.04634492 6.4876101 3.7709946 3.7641245 9.2499997 8.4524089 8.4106527 UBAC1 1.133065064 0.050083269 0.006701436 24.99903401 2.2016907 2.0230478 2.1654208 6.8092213 7.5630806 6.1659595 TAF1A 0.989629606 0.055830986 0.011302255 24.92788342 5.982974 4.9115166 4.9444683 9.6334087 8.6892694 10.6226625 ALPK1 1.054759492 0.051852306 0.008867849 24.8747231 4.2634629 3.8720139 5.2176156 8.5086224 8.9798503 9.14769 SLIT3 0.972251656 0.056976583 0.012110246 24.73397869 4.815804 3.3213504 5.2252164 9.8536389 7.6124139 9.482544 AP3B1 1.121219722 0.050341156 0.006956592 24.49459452 3.8399484 3.360637 2.1654208 7.7378191 7.9750285 7.9791282 LOC649395 1.107263721 0.050608213 0.007357779 24.4656859 6.7367617 7.440099 6.7371315 11.4529988 11.3698308 11.3494495 PPAP2A 1.051192411 0.051900312 0.008970553 24.32673452 5.6586086 4.3899364 4.7244061 8.9944071 9.1057844 10.2745294 EID1 0.878311349 0.070189649 0.019511354 24.14880415 5.7445127 3.8720139 6.0125266 11.0490962 8.4658937 8.7884466 MSX1 0.966291352 0.057324142 0.012483351 23.99322086 5.7794294 6.7629335 8.0377511 11.3474884 11.3929577 10.7209308 A2M 1.083873977 0.051255379 0.008019738 23.95820173 6.5540448 6.2280676 6.9199049 10.3990542 11.2848856 11.5023526 ACTA2 0.776075962 0.101300404 0.036012196 23.84726009 1.8744435 6.0604012 2.1654208 6.4501951 7.3469252 8.4683738 RAB1A 1.034098858 0.052871735 0.009545856 23.78310968 6.186289 6.0497213 6.2829045 11.157649 10.7581544 9.6581778 KAT8 1.002544307 0.054695215 0.010766268 23.74971006 4.309025 2.8096013 3.7641245 7.3794393 7.7728978 8.985824 ANKRD10 0.986272516 0.056015811 0.011451496 23.6877588 6.5861495 4.7507076 6.0125266 9.6198778 9.8289569 11.1522193 TRPT1 0.911731758 0.064396246 0.016122924 23.65405426 2.2016907 3.3213504 2.1654208 5.4258059 8.1688761 6.7657063 COX5A 1.112669548 0.050440463 0.007206933 23.47497516 4.309025 3.8720139 4.7244061 8.4072489 9.5475254 8.8620767 COX8A 1.098023629 0.050846008 0.007598492 23.45824348 7.2186326 6.3520696 6.6706745 10.8118669 11.2226976 11.9635729 EIF3H 1.13843463 0.050038461 0.006598732 23.43898524 6.6482929 7.2617905 7.4620859 11.8164541 11.8126287 11.4838112 DYNLT3 0.944532411 0.059600929 0.013713392 23.36075252 5.8565586 3.8720139 3.7641245 8.6305817 8.3101394 9.2825265 SYTL2 1.106061098 0.050608213 0.007421969 23.23514746 2.2016907 2.406905 2.9956812 6.9015613 6.7399276 9.6076956 ARHGAP15 0.895945684 0.066907118 0.017552756 23.17349422 1.8744435 3.3213504 4.7549172 6.4088472 7.4318221 9.5375148 RGMB 1.06704067 0.051378258 0.008419321 23.0855306 4.2098819 4.8079702 5.2252164 9.001381 8.8210275 9.7541334 DNAJC14 1.067880987 0.051378258 0.008403274 22.92790359 3.8399484 2.0230478 2.9956812 8.1174489 7.1604986 7.5147138 HSPA7 0.910560836 0.064737869 0.016304261 22.87881682 5.3354128 6.1390574 9.7496192 12.948898 13.5238541 9.8513533 SELENBP1 1.033273507 0.052897282 0.009561903 22.84358288 4.6394091 4.7365865 6.0316576 9.1531261 9.3214118 10.4519348 RSL24D1 1.001229982 0.054963463 0.010875391 22.83243116 6.9736463 6.5720715 5.5715986 10.0846112 11.6028209 10.54877 CTSO 1.077450578 0.051291304 0.008181818 22.77973184 5.3285264 6.3119075 5.018694 10.4610743 9.5283729 10.3984929 DDIT4 1.115607564 0.050341156 0.007109043 22.73469649 3.0245043 2.8096013 2.9956812 7.5025051 8.0839766 6.9389568 ADAM22 0.945001049 0.059600929 0.013697344 22.63478525 1.8744435 2.406905 4.4498938 6.7105675 6.9073747 8.5056104 TMEM176B 0.961176425 0.057805981 0.012712028 22.61260454 5.6586086 5.3406193 6.3558005 10.8548558 8.8104958 10.5443033 SPRY1 0.802939311 0.0911622 0.030322555 22.57321793 6.2275774 3.360637 6.0316576 11.2202607 7.8571772 8.8620767 FHL1 0.973697034 0.056754796 0.012004333 22.51591121 6.3818471 3.360637 6.3558005 10.515675 9.0351732 10.8747201 HNMT 1.025699356 0.05313101 0.009769718 22.4774594 3.8197323 4.8304956 4.7549172 8.5280696 8.3101394 10.3274811 SCRN1 0.891362841 0.067695766 0.018038193 22.44028499 4.815804 4.8079702 2.3793449 7.8190025 7.5377667 9.3038231 TUBA1C 0.922344888 0.062363889 0.015244323 22.2288063 5.6586086 6.6385363 4.7549172 8.5941417 11.4483541 10.1329672 PHYHD1 0.931379512 0.06125755 0.014628902 22.12866754 4.2098819 3.360637 5.7236017 7.8347051 8.6777266 9.7463764 LOC100506710 0.947114485 0.059314973 0.013514403 22.06006448 5.3044627 3.360637 2.9956812 8.2753779 7.4590463 8.985824 SARNP 0.94549733 0.059597087 0.013633154 22.00320019 4.2098819 4.7365865 4.2859964 7.3578678 8.7456379 9.9693394 RRAS2 1.041137027 0.052218844 0.009281874 21.97665491 2.2016907 3.8720139 4.5083337 8.3860905 7.8156527 8.3299138 TBL1XR1 0.824889773 0.08448824 0.02661478 21.86482197 6.1437849 5.3406193 6.3692392 10.8197789 7.9937674 10.7676638 PEX19 0.900027743 0.066348129 0.017133114 21.8489524 5.7003762 3.3213504 2.1654208 7.7708426 7.2567201 9.8072951 TMEM223 0.905246977 0.065436968 0.016725508 21.82870119 4.6394091 2.0230478 2.1654208 5.7241063 7.7288372 9.0875635 MBNL2 0.877773417 0.070285138 0.019618872 21.46991007 5.3285264 5.7897017 6.1759311 10.6636862 8.3101394 10.2139459 FOXJ2 0.905385776 0.065436968 0.016717484 21.40455473 3.3509967 2.8096013 4.9444683 7.7708426 9.3724255 6.8257955 LMO4 1.029960252 0.05293768 0.009671026 21.34954394 7.4101728 5.4346801 7.9563845 11.8263061 11.9033876 11.1522193 HDGFRP3 0.932125716 0.06110322 0.014571933 21.34390766 4.6394091 2.8096013 2.3793449 7.147675 7.2253537 8.0564393 STEAP4 1.000010753 0.055166136 0.010942791 21.30360368 6.5540448 6.9314777 7.3175252 10.1829712 11.3445033 13.8917924 SPTSSA 1.110892866 0.050482841 0.007262296 21.18629628 6.0082059 6.3119075 6.4507011 10.6190426 10.8739517 10.4132654 CNTLN 0.779291101 0.100174631 0.035364679 21.18559501 3.0245043 2.8096013 2.9956812 7.400693 4.8088443 7.4397554 C8orf84 0.941363386 0.060058355 0.013929231 21.15229292 1.8744435 4.3899364 2.1654208 6.2771857 8.7784313 7.0438915 ZFP90 0.963704308 0.057515704 0.012627778 21.14604998 3.8197323 2.406905 3.9083598 6.8092213 7.6364622 8.5947028 ARID4B 0.856200545 0.074899345 0.021782075 21.09662862 5.0569476 4.9115166 6.0540376 10.5326233 9.4558882 7.8691489 PDCD6 0.870486295 0.071737566 0.020284041 21.09064583 2.2016907 3.8720139 2.1654208 5.5826351 6.6002221 8.6118796 EFR3A 0.908557594 0.065051314 0.01646634 20.91348244 4.6394091 3.7709946 2.3793449 7.5413002 9.7262434 6.7657063 OLA1 0.9418973 0.059948356 0.013872262 20.91318791 3.8399484 5.3621423 4.9444683 7.7210195 9.7484834 9.5011013 USPL1 1.027712499 0.053094283 0.009727995 20.90533531 4.309025 3.3213504 3.9352215 7.4827092 8.3971729 8.6948242 EFHA1 1.011052628 0.054161962 0.01035465 20.84409197 1.8744435 3.360637 2.1654208 6.988347 7.1604986 6.2560101 EEF1G 1.053201682 0.051900312 0.008930434 20.75732369 9.127293 9.6471417 9.3695859 13.1140369 14.0226902 13.8812053 ITGA7 0.897019636 0.066827455 0.017446843 20.69311928 6.0999914 4.9115166 6.3558005 8.4588258 10.4710706 10.8888821 PDP1 1.087176846 0.051099543 0.007940303 20.64861088 3.8399484 4.3899364 4.2859964 8.2285993 8.5186068 8.7579092 MRPL18 0.955885588 0.058365313 0.012977614 20.60623361 4.2634629 4.8079702 2.9956812 8.2285993 9.8237295 7.3606902 UQCRC2 1.059299864 0.051695193 0.008737864 20.58504727 5.3354128 4.7365865 4.5083337 8.7677808 9.2056159 9.6989376 ARFIP1 0.858203205 0.07443975 0.021506058 20.55462698 4.6820765 4.3899364 3.3243747 8.7513276 6.4455364 9.4156466 DNAJB9 0.982707351 0.056301234 0.011656904 20.52323742 5.7445127 3.8720139 5.3892653 9.4518602 10.1036991 8.6288544 ZFAND1 1.003702266 0.054558959 0.010712509 20.52227622 4.6394091 3.8720139 3.3243747 7.2911484 8.9985279 8.8620767 GNAI2 0.985472847 0.056096089 0.011506058 20.42260955 7.4279993 6.270596 7.1809309 11.7682045 10.2550627 11.7800947 PTPN18 1.012778724 0.054044749 0.010258365 20.38087076 3.8197323 4.7365865 3.7641245 7.8808129 8.1688761 9.33519 TLN1 1.058853562 0.051725293 0.008761935 20.35333457 5.3162271 5.3621423 5.5715986 9.2263843 9.7093356 10.0022812 RAB10 1.075372865 0.051291304 0.008205889 20.18465892 5.3044627 4.3899364 4.7549172 9.5549994 9.63965 8.6786124 NR2F2 0.95581188 0.058394261 0.012993661 20.05485407 9.0602887 4.8304956 6.976024 11.1435335 11.3019035 13.1437919 GMPR 1.036515929 0.05264149 0.00946963 20.04222754 3.3509967 2.8096013 2.1654208 6.4903918 7.0925914 9.0119393 MSH6 0.906915941 0.065226749 0.016585894 19.97124046 4.2634629 2.8096013 3.7641245 6.4501951 8.0839766 8.6622163 PDLIM3 0.870842761 0.071737566 0.020276017 19.95246522 4.7435639 4.4133226 4.7549172 7.0434341 9.062059 9.7695234 RNF103 0.947644285 0.059309685 0.013475889 19.83650498 3.8197323 3.3213504 5.018694 7.7708426 8.4792536 8.1298183 H1FX 0.910275693 0.064737869 0.016336356 19.68868936 8.234634 5.4346801 6.3692392 10.481169 11.5704161 10.6685344 TBC1D15 0.947903505 0.059309685 0.013451817 19.64787657 6.6175557 6.270596 6.0560619 10.6482176 10.9138572 9.4350787 FAM102B 0.911657173 0.064417984 0.016146995 19.53567509 4.2634629 2.0230478 3.3243747 6.4501951 7.6124139 8.0053615 SNRPD2P2 0.982350109 0.05631807 0.011688197 19.41918907 7.2389721 6.3520696 6.3558005 10.1890925 10.7360641 11.5183831 TINF2 0.947284605 0.059309685 0.01349996 19.27906972 4.2634629 3.360637 2.3793449 7.4827092 6.6483084 9.1239392 CD9 1.02651993 0.053094283 0.009744042 19.2567535 3.8197323 3.7709946 3.3243747 8.0382872 9.1648555 7.141714 FAM36A 0.997051405 0.055405156 0.011051914 19.24439227 4.7435639 5.297868 4.5083337 9.3017621 8.2799211 9.5642342 ENY2 0.986572336 0.056015811 0.011427425 19.18086683 4.6820765 2.0230478 3.3243747 8.6748743 7.4318221 7.5859707 CYB561D2 0.940667677 0.060104489 0.013967745 19.17954452 3.8399484 3.3213504 2.3793449 6.6408414 8.3250145 7.0438915 MUT 0.819358001 0.086050848 0.027531894 19.14968888 5.8972917 2.0230478 4.5083337 7.0434341 8.7675828 9.0248218 WAC 0.891139399 0.067798428 0.018076707 19.12960958 6.7367617 5.3621423 7.0300422 9.6198778 9.7758097 13.1124517 ZMAT2 0.893293167 0.067248681 0.017778224 19.02171579 6.1437849 3.360637 4.5083337 8.5755707 8.922321 8.7579092 C1S 0.985498012 0.056096089 0.011498034 18.94088318 6.9491661 7.0583001 8.26876 11.7538223 11.1925978 11.8101721 C11or73 1.000992882 0.054963463 0.010883415 18.88171674 4.2098819 4.3899364 3.7641245 7.5976045 8.5569151 8.6288544 HSD17B11 0.971245962 0.057076743 0.012174436 18.81569836 6.2275774 4.8304956 5.6099449 9.8727797 8.9892193 10.4614424 ANKS1B 0.94148941 0.060032865 0.013911578 18.78225317 5.3162271 3.8720139 4.9444683 8.1428995 9.5475254 8.7267115 SNHG6 1.023424431 0.05332335 0.009855572 18.71829485 7.1980024 7.1522986 7.6289155 11.0029324 11.4243795 13.1460046 PDK4 0.866897983 0.072230876 0.020542406 18.66699306 8.9658158 6.7328249 6.7371315 10.9552425 12.4048378 11.1135456 CADM1 0.886860184 0.068365464 0.01849314 18.57349372 4.2098819 4.3899364 3.7641245 6.6408414 8.4250552 9.6989376 TAGLN 0.914652188 0.063667641 0.015854128 18.56709887 8.8382996 10.9961008 9.5421815 12.5235071 14.8358001 15.2107773 AMD1 0.908125705 0.065125118 0.016506459 18.30652211 4.6820765 5.3406193 6.7692467 10.575312 9.7149936 8.8763623 TFG 0.963965378 0.057515704 0.012619754 18.25927754 4.7435639 4.8079702 2.3793449 8.2521782 8.9985279 8.0053615 RPS18 0.935240153 0.060873607 0.014336837 18.11094714 10.4802403 11.0413399 10.7568342 13.8496561 15.3851924 14.9356243 AIMP1 1.030541317 0.05293768 0.009646955 18.08849656 5.7445127 5.297868 4.9444683 9.1214689 9.7262434 9.6827716 COL12A1 0.894287853 0.067193151 0.017705207 17.99713286 5.3162271 4.8079702 6.7042855 10.8739807 9.7093356 8.6288544 SEPN1 0.917366135 0.063325847 0.015680013 17.97359722 6.0999914 5.6616851 4.5083337 10.3147842 8.4658937 9.8294924 ADM 0.999143484 0.055166136 0.010958838 17.94256562 6.1437849 5.1480825 6.0316576 9.261664 10.6908421 10.1969719 HSD17B12 0.965308956 0.057395438 0.012555564 17.93139787 5.4911209 3.3213504 3.9083598 9.3571784 7.4857665 9.3557287 PRINS 0.900498166 0.066280364 0.017093798 17.79230067 3.0245043 4.4133226 3.7641245 6.6046733 7.9173057 8.9592273 RPL31 1.021311537 0.053385633 0.009928589 17.7388341 9.4617995 10.2275206 9.9968644 13.6106387 14.2235993 14.3361442 TMSB10 0.889019108 0.068085662 0.018298965 17.71732251 7.7305591 8.5268269 8.5897647 13.1027323 12.6739156 10.9710537 SPARC 1.051950508 0.051900312 0.008954505 17.67233245 9.1860944 8.6924512 9.1794888 14.13433 12.8358717 13.251156 NR1D2 0.960093161 0.057945377 0.012769799 17.58211353 4.815804 4.8304956 5.9741452 8.9518406 9.1565634 9.5375148 RGS4 0.914472915 0.06369643 0.01587178 17.54652348 2.993831 3.360637 4.9444683 8.7513276 7.1269443 7.8108476 PSMA2 0.991486891 0.055698998 0.011230843 17.37036986 5.7003762 4.7365865 5.2176156 10.013954 9.3361721 8.8034763 KHDRBS3 0.789226734 0.096254372 0.033117227 17.30725824 2.2016907 4.9115166 6.0540376 6.988347 9.2374148 9.0248218 PRMT3 0.821794565 0.085361525 0.027114659 17.1116875 5.7445127 3.3213504 2.9956812 7.704022 7.0925914 9.1239392 AHNAK 0.810769582 0.088793079 0.028993822 17.10714203 6.5540448 7.3033622 6.2829045 11.399889 8.7675828 11.3443198 GHITM 0.897948926 0.066685485 0.017308032 17.04926294 5.982974 3.360637 4.7244061 8.8160436 8.8418632 8.577319 DNAJC24 0.82869478 0.082955513 0.025913504 17.00807471 4.309025 2.8096013 3.7641245 5.8529567 8.3971729 8.3090028 TMEM183B 0.933450583 0.061000896 0.014477253 16.98492089 3.3509967 3.7709946 4.2859964 6.9599943 7.8571772 8.7108559 MRPL3 0.986593546 0.056015811 0.011419401 16.89398154 4.7435639 4.3899364 2.3793449 7.7708426 8.7233541 8.4683738 CASQ2 0.830920851 0.082259709 0.025578111 16.88543107 3.8197323 2.0230478 2.1654208 6.8406623 5.1121088 7.8974394 PPP1R12A 0.964224668 0.057492262 0.012603707 16.73452716 7.021395 6.4291897 6.5278107 10.0846112 10.6618412 11.0861509 ABCC9 0.982279682 0.056350705 0.011704245 16.69195001 3.8197323 4.8304956 4.7549172 7.8808129 8.65436 9.9759882 GPM6B 0.948805259 0.059219172 0.013375592 16.63555852 5.3162271 4.3513152 3.7641245 7.7210195 9.3724255 8.932131 FOXN2 0.913991292 0.063905039 0.015944797 16.51027049 3.8399484 3.8720139 3.9352215 6.8092213 7.9173057 8.7884466 ASPN 0.982650155 0.05631807 0.01167215 16.48327601 1.8744435 4.3899364 4.9444683 8.9873994 7.89754 8.3299138 C9orf167 0.871058768 0.071735945 0.02025997 16.40786315 4.815804 2.0230478 3.3243747 7.244891 7.4857665 7.3606902 LOC100500773 0.979250363 0.05641197 0.01180053 16.40146769 8.0512583 7.4586165 7.9139132 11.4943695 12.1603217 11.602428 IMMP2L 0.888837151 0.068136485 0.018323839 16.35708965 4.815804 3.7709946 2.3793449 7.147675 7.3469252 8.8476482 SYPL1 0.764521413 0.106201322 0.038838161 16.34027114 5.7003762 4.3899364 4.4498938 9.3787623 6.5504789 9.7307362 PPP1CB 0.927113657 0.061709548 0.014960282 16.232529 8.5678121 8.181467 7.7625708 12.588628 11.3536 12.2189249 GNAI3 0.818569992 0.086383601 0.027723662 16.19136378 5.2636993 4.8304956 4.2859964 9.6289125 7.0925914 8.8476482 SERPING1 0.831375906 0.082162426 0.02550349 16.16475463 5.3162271 5.6616851 5.5929159 10.4960584 7.8156527 9.6076956 ZBTB16 0.784356581 0.098241201 0.034279066 16.03432866 8.3513375 5.6616851 6.3558005 10.3588926 10.9113951 9.9424335 GYPC 0.860338778 0.073930333 0.021220412 16.01423883 7.2186326 4.8304956 5.5446534 8.8317789 10.2743512 10.4278881 TOMM20 0.855825571 0.075059941 0.021853486 15.89461259 6.7367617 5.7897017 4.5083337 8.4987997 10.9951597 9.6664224 WBSCR22 0.917255853 0.063325847 0.015688037 15.87934642 4.7435639 4.7365865 3.9083598 8.0109044 9.1565634 7.8974394 GNPNAT1 0.908372026 0.065072401 0.016482388 15.76346971 1.8744435 3.7709946 2.3793449 5.8529567 7.2253537 7.141714 TAF12 0.748541404 0.113371792 0.042915831 15.72938845 4.2098819 3.360637 2.1654208 5.0495858 8.1852726 7.4397554 IGBP1 0.969565439 0.057171148 0.01232769 15.71850025 5.7003762 6.0361098 6.5278107 10.0105015 11.1618566 9.5642342 DYNC1I2 0.889399583 0.068037763 0.018242799 15.42702692 5.6586086 5.297868 4.7549172 9.7035053 9.2452562 8.1767432 RSU1 0.855107761 0.075307325 0.021987483 15.41332547 5.7445127 6.0726357 4.5083337 9.690619 8.0839766 10.2473064 ANTXR1 0.902145045 0.066071176 0.016985477 15.39138307 4.7435639 5.1957839 6.1759311 9.2732348 9.1398349 9.0248218 PTEN 0.756545048 0.109706101 0.040787932 15.37273905 6.0082059 4.7507076 4.7549172 9.9505082 9.469341 6.9389568 RPS27 0.921934745 0.062446534 0.015282837 15.23068926 11.4342087 11.6153056 12.3217587 15.1118134 15.5442149 16.3577483 ARID1B 0.930611735 0.061334604 0.014709941 15.17974807 5.7794294 5.4346801 5.2176156 9.7035053 8.734539 9.3959492 BTG2 0.836600005 0.080460501 0.024644147 15.17601432 8.062715 7.6317881 8.2231054 12.5021549 11.986436 10.4566964 AP3M1 0.902261075 0.065963593 0.016938939 15.12580138 7.4456083 6.4291897 7.481604 10.9133361 11.6285305 10.3481293 LRRC41 0.818474757 0.086394299 0.027741314 15.11369233 7.0676142 7.1970971 6.4105447 11.1148814 9.3139746 11.0233447 ACTB 0.890474441 0.067913831 0.01815534 15.04416213 5.982974 6.7629335 4.4498938 10.5517522 8.9704199 9.8941059 TMEM106B 0.807350554 0.089824887 0.029508144 14.98109425 4.7435639 3.8720139 3.9352215 9.042531 6.6002221 7.8402926 RAB2A 0.915125416 0.063632534 0.01582444 14.97498509 6.9977182 6.0726357 5.5969865 10.9022008 9.3795682 10.3583437 LITAF 0.987543534 0.056015811 0.011388911 14.9593611 7.0901803 6.9314777 6.976024 12.2706547 10.8790006 10.5443033 CTDSP1 0.8142444 0.087587599 0.028355131 14.91926147 8.1619262 6.3520696 6.7371315 10.6459942 10.2511738 10.9610346 FAM8A1 0.89368479 0.067225527 0.017746931 14.89908179 4.7435639 4.3513152 4.7244061 8.6215576 7.4040744 9.5904678 RPL11 0.917420527 0.063325847 0.015671989 14.81956399 10.6550412 10.6763105 11.0461932 14.0123343 14.5823892 14.9356243 EIF2S3 0.935533137 0.060847991 0.014312766 14.7496231 7.021395 7.0338116 6.3692392 10.2518454 11.8086651 10.4181561 PFDN2 0.96628903 0.057324142 0.012491374 14.74521914 3.8399484 5.4346801 5.2176156 8.6033384 9.2216029 9.0997909 NUP160 0.766079018 0.105517102 0.038440985 14.73626778 4.7435639 4.8079702 4.4498938 6.7770801 8.6892694 8.6288544 COL14A1 0.940714393 0.060104489 0.013959721 14.6794039 5.8565586 6.0924064 6.3267171 11.1731726 9.9681278 9.3143547 GTF2A2 0.861236018 0.073634891 0.021099254 14.66835217 3.3509967 4.3899364 2.3793449 6.7105675 8.2645713 6.8257955 MEF2C 0.972453265 0.056976583 0.012102223 14.60009264 4.6820765 4.4133226 3.9352215 7.8031272 8.2175169 10.3835676 NFIL3 0.893071786 0.067286289 0.017810319 14.59704312 6.6783891 5.3621423 7.4018955 11.2644118 10.5459934 9.6989376 HTR2A 0.880871193 0.06957449 0.019134237 14.59403557 6.4179694 5.3406193 6.0540376 8.8001347 10.1587087 10.2852763 MFN2 0.787417336 0.097112287 0.033612292 14.58611914 3.8197323 2.8096013 2.1654208 6.6761254 5.2428646 7.8691489 MDGA2 0.92651987 0.061745969 0.014991575 14.53576003 2.2016907 2.0230478 2.1654208 6.0269554 5.1121088 8.5419101 ANXA1 0.86503442 0.072750432 0.020714114 14.50515735 6.0999914 8.8196737 7.4620859 11.9404711 11.3205799 11.0201315 C11orf10 0.826621276 0.083744193 0.026311482 14.47696917 7.4101728 6.7020747 6.4507011 11.2658605 9.4147603 10.7327567 NAMPT 0.899404137 0.066432398 0.017187676 14.44686593 7.6416849 6.270596 6.4507011 11.4943695 10.5300335 10.0845675 GBP4 0.885000359 0.068624233 0.018680895 14.38836994 2.993831 4.3899364 3.9083598 6.8406623 7.4040744 9.1825988 ZC3H11A 0.898652074 0.066663913 0.017269518 14.37146758 6.7367617 4.9115166 5.018694 10.0547522 8.756652 9.9219195 CHURC1 0.854047038 0.07547923 0.022074942 14.29183243 5.7003762 4.3899364 5.3892653 9.2263843 7.6601162 10.6395124 METRN 0.800389393 0.092403668 0.030948407 14.21615392 6.186289 4.8304956 3.9083598 7.7378191 8.4111814 10.1210186 RGS5 0.875131616 0.070754858 0.019831501 14.15551048 10.1124251 8.214531 8.54408 11.7722875 13.935717 13.3023141 SNHG12 0.860824133 0.073804927 0.02117227 14.06681488 3.8197323 4.3513152 5.3892653 7.6339561 9.2838364 8.0813159 ANP32B 0.89043607 0.067913831 0.018163364 14.04322846 7.6263253 7.1060646 6.6362622 10.2012578 11.438128 10.9908856 YAP1 0.726124291 0.124034522 0.049366124 14.01822561 7.021395 6.5720715 6.8006628 11.0708071 8.5819002 10.6098946 SEC22C 0.88811537 0.068142722 0.018362353 13.96660489 5.0569476 4.8079702 4.2859964 8.8855392 7.7510357 8.6118796 CHRDL1 0.832537837 0.081828571 0.025265185 13.96431152 5.0569476 3.3213504 6.5278107 10.3314833 8.0305306 8.7884466 UBE2E2 0.828750202 0.082955513 0.025890235 13.88416192 6.0999914 4.8079702 4.4498938 8.6033384 8.0122661 10.0022812 ATAD1 0.820422617 0.085658176 0.027321672 13.84278208 6.5212096 4.8304956 4.5083337 8.6215576 8.5694617 9.6908773 PAIP2 0.89769947 0.066707952 0.017349755 13.77234114 7.1123989 6.0604012 6.3267171 10.1829712 10.6352324 9.8441031 RPL15 0.91125945 0.064608431 0.016215999 13.68730107 10.4146938 10.0798307 10.175278 13.3603952 14.1894599 14.1865251 GTF2H5 0.793331984 0.094918088 0.032337318 13.653898 5.3354128 3.3213504 5.3892653 8.4177128 7.0925914 10.1029082 PSMA4 0.845247147 0.07794672 0.023224745 13.62416608 5.7794294 5.6616851 3.7641245 8.6215576 9.5475254 8.4301508 LOC100129480 0.821054607 0.085473525 0.027220573 13.56111025 5.0569476 4.3513152 6.4105447 8.3967085 9.5601539 8.818351 MSRB3 0.884650914 0.06867652 0.018729038 13.55847085 5.2636993 5.4346801 4.2859964 8.0382872 9.2608123 9.0248218 EPS8 0.756418019 0.10976326 0.040827249 13.49071421 6.8201191 6.0361098 6.0540376 8.3317959 9.8079324 11.3596546 XIAP 0.94272791 0.059848162 0.013809677 13.44324316 6.7650859 6.6706551 5.6099449 10.4174205 10.5138952 9.9080797 PCBP4 0.90225861 0.065963593 0.016946963 13.30588266 4.6394091 4.9115166 4.7549172 8.4889095 7.8365643 9.3454959 TMEM109 0.896518772 0.066891468 0.017504614 13.23484742 4.6394091 3.7709946 4.2859964 8.4384157 8.0122661 7.4007641 RPL13AP20 0.877873407 0.070255881 0.019587579 13.18153468 11.4075 11.9474319 11.7842038 14.668965 15.6678784 15.6610764 ARHGAP6 0.754587312 0.110509614 0.041307069 13.17146169 7.0446897 3.360637 5.3892653 9.1086088 8.3250145 9.3759791 BRP44 0.952738879 0.058717048 0.013155741 13.14009898 5.0569476 4.8079702 2.9956812 8.3537595 8.5819002 8.5238744 TMEM64 0.839898422 0.079307362 0.024056006 12.99663839 6.3818471 5.8096013 7.4018955 11.1019621 9.4216969 10.225152 IGFBP3 0.855966107 0.075059941 0.021845463 12.99561165 6.7650859 5.3621423 6.0540376 10.575312 9.7539902 9.0375903 GFRA1 0.848370253 0.077303306 0.022846827 12.95239124 6.3447976 5.3621423 7.0032858 10.6984324 9.2295305 9.9626598 OBFC1 0.833824268 0.08138461 0.025022065 12.87646451 4.6820765 4.8079702 3.7641245 6.7442069 8.3687411 10.0784017 C6orf62 0.806529204 0.090187602 0.029671829 12.77674175 7.1558353 5.3621423 6.3267171 10.4174205 10.0819703 9.0375903 PSPC1 0.848312388 0.077303306 0.02285485 12.76451011 4.2098819 4.7365865 5.7236017 8.2638247 8.734539 8.4106527 PPP2R2A 0.919897851 0.06299636 0.015502688 12.69878235 4.815804 5.1957839 5.3892653 8.4281014 8.8624022 9.32481 CEP68 0.805182069 0.090395406 0.029844339 12.6668481 5.3044627 3.3213504 4.5083337 8.7008115 6.9843361 8.4106527 NEMF 0.886849834 0.068365464 0.018509187 12.58795995 6.186289 5.297868 2.1654208 8.9518406 9.1057844 8.833074 ATL1 0.88032251 0.069612081 0.019190404 12.53921637 4.6394091 3.7709946 3.3243747 7.9545288 6.9073747 8.2877844 CXCL12 0.848861391 0.077198422 0.022781032 12.53209292 7.4971815 7.2617905 9.3107812 12.9583367 10.5459934 12.671147 FGD5-AS1 0.828839559 0.082955513 0.025882211 12.48870381 6.8201191 6.0726357 6.1759311 10.6962851 9.818483 9.14769 ARPC3 0.811201413 0.088696214 0.028906363 12.44831219 6.3447976 4.8304956 3.9083598 9.5165726 8.2175169 8.4683738 FAM200B 0.812901739 0.088144268 0.028607879 12.44323818 4.7435639 5.1957839 3.7641245 7.4827092 7.956043 8.833074 ARMC1 0.831038389 0.082217411 0.025547621 12.4263524 5.7794294 5.4346801 3.3243747 8.6124767 9.4147603 8.0311264 NARFL 0.852386776 0.075877883 0.022228998 12.39814856 3.8197323 2.0230478 2.1654208 5.6551006 7.4318221 6.496723 ETFA 0.874096683 0.070954628 0.019934205 12.38389774 4.7435639 4.9115166 2.1654208 7.3794393 8.2490564 8.5419101 HDDC2 0.790933841 0.095718911 0.032783439 12.35546194 5.6586086 5.3621423 5.2176156 7.8190025 8.9892193 9.6415459 PCBD1 0.81978204 0.08595687 0.027445238 12.25462899 5.982974 5.7897017 4.9444683 9.7035053 8.8418632 8.5597232 GLUL 0.938475604 0.060337931 0.01411137 12.23713573 8.0740814 7.0089004 8.2346552 11.776359 11.6872754 11.5274641 GCFC2 0.846975683 0.077594277 0.022987242 12.16765085 4.6394091 3.7709946 2.3793449 7.244891 6.8260777 8.2443879 TCP1 0.821839578 0.085361525 0.027106636 12.12563722 6.0548278 6.1842483 6.8910052 10.3147842 10.4909939 8.9457427 SF3B1 0.893056562 0.067286289 0.017818342 12.04916889 5.982974 4.3899364 5.6099449 9.5738357 8.8926726 8.985824 NR3C1 0.870071476 0.071776816 0.020330579 12.04450485 6.2275774 4.7365865 5.9741452 9.5644483 8.8926726 9.6331575 C10orf26 0.728929501 0.12296007 0.048493942 12.01722991 6.6175557 3.8720139 3.9352215 8.5086224 7.4590463 8.8476482 MAP7D3 0.763281078 0.10685386 0.039156704 11.99484074 3.8197323 2.0230478 2.9956812 5.8529567 7.4040744 5.8563328 HNRNPA0 0.855576216 0.075140343 0.021901629 11.99027384 7.8805094 7.0089004 7.8250252 11.8679196 11.0874723 10.5926931 ANK2 0.804168668 0.090775559 0.030104309 11.87419279 3.8197323 4.3513152 5.3892653 8.9590228 7.1604986 8.1767432 PPIA 0.873594632 0.07101993 0.019975929 11.75274209 6.5540448 6.7629335 6.3267171 9.5262757 11.0874723 10.1089703 TRIM4 0.892260879 0.067567176 0.017948327 11.74747067 1.8744435 3.8720139 3.9083598 7.4626381 6.8672984 7.2333272 UBE2L6 0.76739738 0.104951556 0.038123245 11.65311685 6.4179694 4.3513152 4.9444683 9.7205099 7.9937674 8.4871122 SAP18 0.856343613 0.074882017 0.021752387 11.63961466 7.6108005 6.7020747 7.2956386 10.2430461 10.9454868 10.9908856 IRS2 0.784635392 0.098241201 0.034238947 11.62981855 7.9805393 7.6153768 8.685452 12.2252087 11.6800618 10.575284 STAG1 0.766157825 0.105517102 0.038432962 11.59690944 2.993831 3.7709946 4.9444683 6.5294995 7.5630806 7.8402926 ADCY6 0.861887475 0.073515148 0.021020621 11.56158826 4.309025 4.8079702 2.9956812 7.400693 8.0663803 7.8402926 DPYSL2 0.806313842 0.090221715 0.02971275 11.5539731 7.9188379 6.0361098 7.2046135 11.4247442 9.5664269 11.1898834 RPLP2 0.811964359 0.088607313 0.028816497 11.53303828 11.9574379 12.1454554 12.1638325 14.7428672 15.6731561 15.8474469 XRN1 0.762923418 0.106946495 0.039286689 11.4231475 5.3044627 5.3406193 4.4498938 7.0964955 9.585084 8.818351 SPRED2 0.816394046 0.086958113 0.028017331 11.35686286 4.7435639 4.7507076 3.9083598 9.0891013 8.2490564 6.9389568 ITM2A 0.827219202 0.083495213 0.026178288 11.35248957 5.0569476 5.1957839 6.7692467 12.7556967 8.7007207 8.5597232 BZW1 0.743063913 0.116342943 0.044423494 11.3465869 7.3553323 7.6153768 7.3603269 10.9371717 9.6749135 11.1195633 MSMO1 0.895471257 0.067048563 0.017600899 11.25024034 5.3162271 4.7365865 2.3793449 8.8081111 8.0305306 8.1767432 IRF2BP2 0.85567373 0.075127708 0.021885581 11.23545061 7.5139709 7.1970971 8.114773 11.5655021 10.8013455 11.003957 F5 0.809705695 0.089166903 0.029159913 11.23407095 4.7435639 4.3899364 5.3892653 7.8808129 8.2333728 8.3090028 C1orf55 0.826119237 0.083959567 0.026420605 11.22750064 4.963444 4.3513152 5.2176156 10.3425096 8.4524089 7.3194719 ARID5B 0.838880462 0.079552776 0.024222097 11.20842419 7.4971815 6.1842483 8.5253933 10.9836931 11.7214074 10.7979987 BAZ2B 0.851873338 0.076086529 0.02232769 11.19833906 4.963444 2.0230478 5.3892653 8.4486569 8.6892694 7.6538745 GLT8D1 0.756167544 0.109799836 0.040876996 11.18069702 5.3354128 4.7365865 4.2859964 8.2521782 7.1269443 8.818351 COPB2 0.780413175 0.099833202 0.035079836 11.15019582 6.3067721 4.8304956 3.9352215 8.3094927 8.0122661 9.4637448 EPAS1 0.795185177 0.094440529 0.032065313 11.13704826 9.417868 8.5529154 7.9423658 11.5513158 12.0302104 12.5017958 MLL5 0.861482611 0.073581947 0.021071973 11.09848594 7.2788106 6.3119075 7.1568531 10.7511015 10.3121715 10.2691257 CUTA 0.878573558 0.070068758 0.019443152 11.08631047 6.8989234 6.8496647 6.7692467 10.3203721 9.9822728 10.575284 KDELR2 0.725237177 0.124340802 0.049626093 11.05074583 9.0885863 7.7567626 7.8848881 12.5546582 10.0599091 12.2203256 POLR2C 0.780455965 0.099816017 0.03505737 11.04375185 5.0569476 3.360637 3.9352215 8.3753938 7.5120008 6.8257955 MAP9 0.793472674 0.094918088 0.032322073 10.88186968 6.8989234 4.4133226 4.5083337 9.8727797 7.8571772 9.4542526 STOML2 0.825395025 0.084246978 0.026524914 10.88119993 6.9736463 5.1957839 5.2176156 8.6395496 9.7093356 10.1797958 PPFIBP1 0.900382913 0.066297168 0.017109043 10.83045106 5.2636993 5.4876732 5.3892653 10.2489183 8.7007207 8.7267115 FABP4 0.795096253 0.094440529 0.032081361 10.7891167 6.2677178 7.5127845 7.5934735 9.6992226 10.7332789 11.5183831 CCDC152 0.771249521 0.103361885 0.037221375 10.73287898 6.2677178 6.270596 7.9139132 11.3378784 10.2236543 9.3959492 PSMB1 0.820919126 0.085550248 0.027259087 10.67551065 6.6482929 4.9115166 5.7236017 8.9446225 9.1398349 9.8585673 LACTB 0.74997367 0.112655516 0.042459279 10.67047795 3.8197323 2.8096013 3.3243747 5.4258059 6.7399276 8.0813159 THY1 0.790197086 0.095932777 0.032919843 10.65897244 5.7003762 6.7328249 6.7042855 10.8891001 9.1143726 9.5375148 TNFRSF10B 0.823626154 0.084832597 0.026812966 10.65530237 6.4876101 6.3520696 7.2508437 10.4610743 9.8496795 9.9011097 RPS27L 0.743906468 0.115861858 0.044163524 10.56179378 8.085359 6.537655 6.0540376 10.2807948 9.2685279 11.486142 RDX 0.806764669 0.090105859 0.029630105 10.4205879 6.0082059 4.8304956 4.7244061 9.1902202 8.6064601 8.1057709 AP1G1 0.739016742 0.118062901 0.045663163 10.41875502 6.1437849 4.4133226 4.4498938 8.5472581 7.7944336 8.350526 MPHOSPH8 0.80426854 0.090718963 0.030070609 10.33872951 8.234634 7.282726 7.5571389 11.3705641 10.6764145 10.9271259 BBX 0.845222161 0.07794672 0.023232769 10.24247886 6.4876101 5.1480825 6.1759311 9.4969685 9.1398349 9.8441031 RWDD1 0.795884361 0.094227095 0.031931317 10.23174627 7.373845 7.9523826 7.0563116 10.1921435 11.5719758 10.7288255 COMMD6 0.735226165 0.11955052 0.046612373 10.209609 6.6482929 8.2784691 8.7350882 10.3831235 11.2424208 12.0869439 ARL6IP4 0.753531554 0.111173921 0.041626414 10.11038492 7.7015384 6.6385363 6.0560619 9.4569424 9.9101189 11.0393044 CIZ1 0.824390792 0.084691716 0.026720693 10.08547882 4.2098819 3.360637 3.9083598 7.0161533 6.6948447 8.7423946 NGDN 0.806379437 0.090221715 0.029704726 10.04378133 4.6394091 4.3899364 4.5083337 7.147675 7.8365643 8.833074 PRPF38B 0.814006316 0.087666999 0.028401669 10.03580366 6.4179694 6.7328249 7.0300422 9.4416416 10.0599091 11.1225628 DTYMK 0.7343269 0.120303656 0.046965418 9.973951109 6.5212096 5.6616851 3.9083598 8.0651599 8.9798503 9.1710561 KLF4 0.802408973 0.091256582 0.030414026 9.95759097 6.3818471 6.9314777 7.8096632 10.8872188 10.2472744 10.1682304 ARF6 0.826941548 0.083599382 0.026230442 9.900203357 7.786906 8.3195726 8.5625279 12.4238576 11.6270308 11.0644784 CLSTN1 0.824145345 0.084705069 0.026744765 9.803034952 5.982974 5.1957839 5.3892653 8.930077 9.2762025 8.4683738 SF3B14 0.732678491 0.121002258 0.047323277 9.790926277 4.6394091 5.4876732 5.018694 7.1223122 8.3101394 9.6746202 FBXO32 0.742217933 0.116885203 0.04466902 9.777346435 6.0999914 6.5023977 4.4498938 9.3894343 9.4216969 8.2443879 GNB2L1 0.856705399 0.074812109 0.021707454 9.730049602 10.0789648 9.9998997 10.1480512 13.3614119 13.2194954 13.6080838 SERF2 0.816085647 0.086958113 0.028065474 9.715628863 7.5951068 6.9577495 7.4018955 10.9534456 10.6822029 10.2139459 TTC17 0.789448888 0.0961872 0.033054642 9.711989783 4.7435639 4.4133226 3.7641245 7.268205 9.4216969 7.0438915 ANO7 0.751433464 0.112148902 0.042120677 9.59215601 5.0569476 5.297868 5.5446534 7.4827092 9.9869572 8.5597232 HSPE1 0.741951881 0.117013269 0.044756479 9.580184638 6.6783891 7.939256 7.5754206 10.835474 11.5082338 9.6664224 CD4 0.731944187 0.121372077 0.047542325 9.571507262 4.963444 3.8720139 6.0721689 7.704022 8.7784313 8.2221901 ZCCHC9 0.822130593 0.085361525 0.027082564 9.516284116 5.8972917 5.297868 3.3243747 8.3094927 8.3543123 9.14769 PRKD3 0.779991955 0.099902938 0.035178528 9.508665498 4.815804 5.4346801 6.0721689 9.1531261 9.3214118 7.9524091 SLU7 0.772266119 0.103092658 0.036988687 9.490976356 5.982974 5.297868 6.0316576 8.0517861 9.2295305 10.3835676 TRA2A 0.79776008 0.093697465 0.031659312 9.483417779 6.7928648 6.3119075 7.1323668 10.3777739 10.2589411 9.473175 TINAGL1 0.763896816 0.106557388 0.038995426 9.414495775 6.2275774 8.0894025 6.8910052 9.2382403 11.3242864 11.2542022 NRN1 0.792012044 0.095431107 0.032653454 9.368150281 5.2636993 4.3513152 5.2252164 7.5790795 9.2989842 8.2662493 TAP1 0.771449011 0.103268709 0.037170826 9.231131614 6.0999914 4.3899364 6.0721689 8.9005384 9.3064989 8.4683738 GOLTIB 0.758192283 0.109295557 0.040473401 9.185277219 7.0446897 6.3911446 5.5929159 9.7703533 9.2295305 9.5904678 EEF1A1 0.804961547 0.090458328 0.029894889 9.118221008 12.2601471 11.9918161 12.5153 15.4488994 15.8390843 15.1507049 FOXO3 0.739397768 0.1180144 0.045522747 9.077014441 7.7448535 6.6706551 8.0245047 10.1170787 11.2067226 10.5970127 SPTAN1 0.778798295 0.100470987 0.035485838 9.060517648 5.7794294 4.8304956 6.3558005 8.9590228 8.6660906 9.2166829 PTPN12 0.7986597 0.09326714 0.031421809 9.046527085 6.5540448 6.0726357 6.564874 9.2499997 9.7812134 9.7149245 IGFBP6 0.798794549 0.093160485 0.031347188 9.029994426 6.7367617 6.2280676 6.4897707 9.6644958 9.802628 9.4253954 EXOSC1 0.746844264 0.114273666 0.043407687 9.029433269 4.7435639 4.4133226 3.7641245 6.6761254 7.5879581 8.3090028 AKT3 0.731883481 0.121384784 0.047572816 9.017307225 7.1342805 5.3621423 6.3558005 8.8855392 10.0193285 9.5284972 C2orf28 0.745362914 0.115114708 0.043784001 8.996396945 6.2275774 5.3621423 3.9083598 9.001381 8.5314896 8.0053615 MALAT1 0.771461089 0.103268709 0.037162802 8.909143621 10.7555327 10.4027151 11.5361053 14.3258503 14.5371937 13.5580019 ITPRIPL2 0.731552532 0.121504123 0.047714034 8.879622299 7.0446897 6.3911446 5.9741452 10.195188 8.922321 9.5904678 NDUFAF2 0.794539832 0.094647408 0.032167215 8.740510082 6.8731305 6.1842483 6.0316576 9.1593751 9.7703857 9.9492072 SOWAHC 0.752162632 0.111864532 0.041961005 8.612717825 5.2636993 5.4876732 6.0540376 8.5941417 8.5569151 8.6622163 KTN1 0.727540118 0.123357599 0.04896975 8.600192586 5.8565586 4.3899364 3.9083598 8.7008115 8.9609276 6.7030085 DNAJC27 0.798691215 0.093241241 0.031397737 8.594323591 5.3354128 4.8079702 4.9444683 7.9107527 8.4387969 8.2662493 PLEKHH2 0.771739161 0.10322713 0.037106636 8.583847152 5.3285264 6.0361098 5.7236017 10.013954 8.5942324 8.4301508 HIGD2A 0.724166466 0.12474266 0.049914146 8.5025188 5.8565586 4.8079702 5.5446534 7.8958605 8.3543123 9.1710561 IMPDH2 0.785690282 0.097887794 0.033977373 8.497098131 5.7445127 6.2280676 6.0316576 9.4720826 8.831483 9.0997909 PTGES3 0.759187807 0.108650799 0.04014523 8.479227622 8.2039211 7.7567626 8.4872775 11.4363698 10.8406955 11.369788 PRRC2C 0.727843513 0.123293242 0.048863035 8.446888491 8.9473922 9.0199958 8.1639276 12.0984158 11.6987427 11.3105244 VEGFB 0.737366924 0.118603779 0.04606756 8.38947916 6.6175557 5.1480825 5.3892653 8.2166637 8.9798503 9.6076956 GGCX 0.808858608 0.089366489 0.029298724 8.363983186 6.2275774 6.7020747 6.8314096 9.7662649 9.8802157 9.6908773 NAA40 0.777390992 0.100997357 0.035771484 8.270024433 6.4532097 6.0924064 5.7029118 9.062674 9.0531526 9.5011013 LOC100505806 0.750958224 0.112223511 0.042222579 8.238156309 5.3285264 4.8079702 5.3892653 7.7210195 8.6306088 8.3708479 NMD3 0.751117871 0.112223511 0.042184065 8.21400123 5.3162271 5.1957839 5.7236017 7.8190025 8.3543123 10.1565715 PSMD6 0.751067056 0.112223511 0.042192089 7.930604712 5.7445127 5.1480825 5.018694 7.9254928 8.1355133 9.5991074 PSAP 0.727966231 0.123245219 0.048815694 7.930336744 9.3162351 8.4456055 9.0481921 12.8172612 11.4329877 11.8212914 PTPN14 0.745990948 0.114727673 0.043617909 7.861074951 5.3354128 6.0441977 2.9956812 7.704022 8.3101394 8.985824 RNF146 0.743577286 0.116083282 0.04426703 7.792187433 5.0569476 5.4346801 5.5969865 8.3967085 8.65436 7.9791282 RSBN1 0.731873193 0.121384784 0.047587258 7.700979791 6.3067721 3.360637 6.3267171 8.0784109 9.2136315 9.2717591 METAP2 0.746981866 0.114203645 0.043343497 7.628749906 6.1437849 4.4133226 6.6362622 9.1963108 8.8624022 9.0752315 PPP1R2 0.755372689 0.110198518 0.04110808 7.54336207 4.815804 4.7365865 3.7641245 7.6517941 6.6483084 9.6989376 TMEM51 0.762670859 0.106981687 0.039334831 7.480659068 5.3162271 6.0726357 6.0560619 8.7093547 8.9704199 8.9592273 RPL13 0.736262615 0.119102493 0.046378881 7.3459284 12.3120719 12.3821266 12.4523907 14.907489 15.2590714 15.9687652 TSPAN3 0.724995864 0.124466391 0.049696702 7.228570825 7.9561744 7.4213407 6.3558005 10.2750512 10.1669886 10.5034676 LARP7 0.724530127 0.12468513 0.049810639 7.222019893 5.8972917 5.4346801 5.5969865 8.0651599 9.6632545 8.4493889 PEAR1 0.789096967 0.096303907 0.033158148 7.173081778 5.3354128 2.0230478 5.7236017 8.5661948 8.1522912 8.0564393 PSMD7 0.727750668 0.123353368 0.048907165 6.881426431 7.0901803 6.4662577 4.4498938 9.2084155 8.9609276 9.8728879 NUAK1 0.755377417 0.110198518 0.041100056 6.386668583 6.8468682 2.0230478 7.5198657 9.2961016 9.5219318 10.0344875 TNFRSF18 −0.867019435 0.072221888 0.020527963 0.039506385 5.2636993 8.8895842 8.6599785 5.9133149 1.2054667 0.6019289 RGS14 −0.768464034 0.10469499 0.037908208 0.038093846 5.3162271 7.7863852 7.6635078 5.9712523 1.2054667 0.6019289 GAL −0.727426869 0.123381232 0.048999438 0.030832695 2.2016907 10.7793494 11.9209565 6.9015613 1.2054667 0.6019289 AIF1L −0.840537939 0.079141153 0.02393244 0.028309227 5.7445127 9.0508366 8.9812053 6.8092213 1.2054667 0.6019289 CD101 −0.796285688 0.094083369 0.031867127 0.028309227 5.7445127 8.181467 8.458015 6.6046733 1.2054667 0.6019289 CD3E −0.805206584 0.090395406 0.029836315 0.020842034 6.186289 7.282726 10.117184 7.0161533 1.2054667 0.6019289 AXIN1 −0.762244952 0.107082149 0.039389393 0.018673437 6.3447976 7.885522 7.5008617 6.7442069 1.2054667 0.6019289 STAT4 −0.724193033 0.12474266 0.049898098 0.018083082 7.4456083 6.3911446 8.6252987 7.5025051 1.2054667 0.6019289 ACVR2A −0.728607126 0.123036393 0.048578994 0.01774996 6.4179694 7.1522986 7.7625708 6.8714329 1.2054667 0.6019289 THOC6 −0.72710556 0.123566409 0.049093316 0.016666186 7.1123989 7.0338116 8.1639276 7.4626381 1.2054667 0.6019289 RLIM −0.736510971 0.119030883 0.046292225 0.01603187 8.3699022 8.5002579 8.9535147 8.8627439 2.5373444 0.6019289 ALS2CL −0.809500504 0.089247119 0.029200834 0.01294733 6.8731305 9.4804432 7.6804979 7.4626381 1.2054667 0.6019289 TNF −0.757233013 0.109484618 0.040651529 0.012472543 7.5305672 9.4155716 7.2046135 8.1174489 1.2054667 0.6019289 SLC4A7 −0.731769694 0.121411587 0.047617749 0.011426949 7.6568826 7.6153768 8.0111355 8.0109044 1.2054667 0.6019289 EXOSC2 −0.767700479 0.104951556 0.038035786 0.011124148 7.4801945 7.6956281 7.8701536 7.5025051 1.2054667 0.6019289 SLC7A6 −0.78451864 0.098241201 0.034246971 0.010487801 7.1770729 7.9653908 8.1759589 7.4626381 1.2054667 0.6019289 SKP2 −0.740635906 0.117680421 0.045139212 0.009570616 7.9925691 7.9126391 7.6113033 8.0517861 1.2054667 0.6019289 LIMD1 −0.740129831 0.117838959 0.045289256 0.009286124 7.9561744 7.6317881 8.0111355 8.1045532 1.2054667 0.6019289 LRRFIP2 −0.801591152 0.091706201 0.030624248 0.009284772 7.943836 8.8758705 7.9563845 8.1045532 1.2054667 0.6019289 ISG20L2 −0.773253949 0.102731018 0.036767231 0.008980224 8.0044995 7.926009 8.2799514 8.1045532 1.2054667 0.6019289 RNF149 −0.749616412 0.112869889 0.042577229 0.008906872 8.016332 8.3984252 7.9976413 8.4689236 1.2054667 0.6019289 SIK3 −0.750578967 0.112470747 0.042334109 0.008834709 8.0280683 7.939256 8.9181369 8.7093547 1.2054667 0.6019289 SORBS1 −0.823563365 0.084832597 0.02682099 0.008400829 7.4971815 8.8963925 9.0932984 8.2285993 1.2054667 0.6019289 MAN1A1 −0.759865974 0.108225602 0.039970312 0.008234283 8.1296079 7.5987767 8.3873354 8.180253 1.2054667 0.6019289 EP400 −0.773589899 0.102608214 0.036679772 0.007992855 8.1725401 8.1476275 8.5625279 8.4789512 1.2054667 0.6019289 SUN1 −0.763245699 0.10685404 0.03918238 0.007591562 7.7448535 8.2468542 8.4281467 8.3206874 1.2054667 0.6019289 CLIC2 −0.778371509 0.100596765 0.035546819 0.006713412 8.4242047 7.8717699 9.8393517 9.0559909 1.2054667 0.6019289 SLC39A14 −0.740179162 0.117838959 0.045273209 0.006408378 8.7418194 8.4912918 7.9423658 9.001381 1.2054667 0.6019289 ALDH1A2 −0.889153515 0.068037763 0.01826687 0.00610395 8.2142315 8.5615078 10.172278 8.3206874 1.2054667 0.6019289 HS6ST1 −0.762719163 0.106964099 0.03931076 0.005962331 8.2244688 8.5953745 9.243773 9.2499997 1.2054667 0.6019289 ENPP2 −0.784959192 0.098230159 0.034161117 0.005861952 8.016332 8.9031688 10.3867524 9.6153392 1.2054667 0.6019289 VCAN −0.751810338 0.112027084 0.042056487 0.005157503 8.8045782 8.2784691 10.36852 10.1041793 1.2054667 0.6019289 ITGA5 −0.809190402 0.089304414 0.029248977 0.005148384 9.3114408 8.2035936 9.7576474 9.3841082 1.2054667 0.6019289 IL1R1 −0.730474898 0.122181851 0.048064671 0.004814919 9.1702939 8.7907325 8.9037393 10.097686 1.2054667 0.6019289 CXCR4 −0.930425312 0.061359395 0.014734013 0.004445723 8.4152951 9.0988503 11.4433385 8.8395827 1.2054667 0.6019289 HTRA3 −0.74927297 0.113077513 0.042692771 0.004240561 8.6910467 9.0869958 9.4260873 10.064774 1.2054667 0.6019289 PFKFB3 −0.74347702 0.116136259 0.044306347 0.00420586 8.9960085 9.0988503 9.7853995 10.5181084 1.2054667 0.6019289 RALGDS −0.880007525 0.069702623 0.019249779 0.004138105 8.518743 9.4060615 9.3324431 8.6573201 1.2054667 0.6019289 PLN 0.800820775 0.092142061 0.030830458 −0.002312924 1.8744435 2.0230478 2.1654208 1.0866873 11.124081 10.7791142 GIGYF1 −0.735951558 0.119192232 0.046433443 −4.98595154 10.8445084 10.6842005 10.7285216 8.8703825 1.2054667 8.4106527 LRRC27 −0.757831076 0.109363019 0.040519939 −5.636335447 9.7650691 10.0738369 10.3367183 7.5790795 7.9937674 0.6019289 BAZ1B −0.778109877 0.100704268 0.03560138 −5.783886136 10.2665157 10.4566846 10.7366678 8.2046286 8.0305306 0.6019289 HSPA9 −0.754789861 0.110502458 0.041247693 −5.839258562 10.2540769 10.0678182 9.9832349 7.522033 8.1852726 0.6019289 ATP6V0E1 −0.76481696 0.106064219 0.038753109 −6.087695409 11.0266571 10.8858173 10.7747461 9.0152285 8.2799211 0.6019289 ASF1A −0.74922976 0.113096218 0.042718447 −6.329147002 9.1702939 8.8963925 9.1122062 6.4501951 7.0574008 0.6019289 ILF2 −0.805425599 0.090359119 0.029802616 −6.371218557 11.4914952 11.9433284 11.77731 9.1902202 1.2054667 9.2717591 FRMD6 −0.783811429 0.098383162 0.034392201 −6.562905055 10.7034196 11.0911502 10.8156954 8.8703825 8.1013608 0.6019289 WDYHV1 −0.741665829 0.117170459 0.044855171 −6.586086605 6.186289 3.3213504 3.7641245 1.0866873 1.2054667 0.6019289 RGP1 −0.735681491 0.119263365 0.046480783 −6.586086605 5.8972917 3.3213504 3.7641245 1.0866873 1.2054667 0.6019289 KRT6B −0.744542726 0.115549059 0.044006259 −6.648574266 3.8197323 7.8154118 2.9956812 1.0866873 1.2054667 0.6019289 DDX19A −0.729250965 0.122818874 0.04839204 −6.648574266 3.8197323 3.3213504 5.3892653 1.0866873 1.2054667 0.6019289 C1orf116 −0.748784302 0.11325619 0.042826767 −6.742394852 3.8399484 6.1842483 3.3243747 1.0866873 1.2054667 0.6019289 C3orf45 −0.726813317 0.123667925 0.049174356 −6.742394852 3.8399484 3.3213504 5.2176156 1.0866873 1.2054667 0.6019289 EXOSC10 −0.725663986 0.124142562 0.049485678 −6.742394852 3.8399484 3.8720139 3.7641245 1.0866873 1.2054667 0.6019289 C14orf80 −0.725663986 0.124142562 0.049485678 −6.742394852 3.8399484 3.8720139 3.7641245 1.0866873 1.2054667 0.6019289 PNPLA2 −0.798814577 0.093160485 0.031323116 −6.743481091 11.0670382 11.5584909 11.1181107 8.3646172 9.2056159 0.6019289 IGF2-AS1 −0.750010672 0.112640836 0.042435208 −6.767899146 3.8399484 3.360637 6.0540376 1.0866873 1.2054667 0.6019289 AP3M2 −0.739119149 0.118017692 0.045626254 −6.767899146 3.8399484 3.360637 5.5446534 1.0866873 1.2054667 0.6019289 EIF2B5 −0.756284617 0.1097794 0.04085132 −6.801867543 10.0533501 10.4704377 9.3903888 8.0784109 7.2874192 0.6019289 ZNF219 −0.748675552 0.11328963 0.042866084 −6.809091159 9.2969617 9.5554851 8.7269332 6.5294995 1.2054667 7.141714 IDI1 −0.739338591 0.1180144 0.045554842 −6.851800368 10.1234083 9.0569264 10.2848865 7.9107527 7.3469252 0.6019289 TTC27 −0.736331318 0.119080705 0.046350798 −6.893929505 3.8197323 3.8720139 3.9083598 1.0866873 1.2054667 0.6019289 EXOC6B −0.736331318 0.119080705 0.046350798 −6.893929505 3.8197323 3.8720139 3.9083598 1.0866873 1.2054667 0.6019289 BRSK2 −0.732825648 0.120980991 0.047289577 −6.893929505 5.3285264 3.8720139 3.3243747 1.0866873 1.2054667 0.6019289 HMX3 −0.732825648 0.120980991 0.047289577 −6.893929505 5.3285264 3.8720139 3.3243747 1.0866873 1.2054667 0.6019289 PYG01 −0.731610332 0.121504123 0.047697986 −6.893929505 3.0245043 3.8720139 6.7371315 1.0866873 1.2054667 0.6019289 RNF4 −0.746849112 0.114273666 0.043399663 −6.917140287 10.0155294 9.6751249 10.1480512 8.2285993 7.2253537 0.6019289 C16orf86 −0.728635031 0.123036393 0.04857097 −7.06981506 5.0569476 3.3213504 3.9083598 1.0866873 1.2054667 0.6019289 CCK −0.728059626 0.123245219 0.048790018 −7.06981506 3.3509967 4.9115166 3.9083598 1.0866873 1.2054667 0.6019289 TOR1AIP1 −0.740044453 0.117838959 0.04532777 −7.160851517 9.3305229 9.1792112 9.4997334 6.4903918 7.7062919 0.6019289 REXO2 −0.747909667 0.113710993 0.043100377 −7.168174054 10.9911217 10.7976487 10.6160036 9.3352666 7.956043 0.6019289 CNKSR1 −0.752078898 0.111864532 0.041977052 −7.202682103 3.3509967 5.7897017 3.9352215 1.0866873 1.2054667 0.6019289 LOC283553 −0.737485942 0.118571391 0.046035465 −7.202682103 5.3044627 3.3213504 3.9352215 1.0866873 1.2054667 0.6019289 TAL1 −0.728332919 0.123091778 0.048645591 −7.202682103 4.963444 3.3213504 3.9352215 1.0866873 1.2054667 0.6019289 C8orf75 −0.725502838 0.124199978 0.049529006 −7.202682103 3.3509967 4.7507076 3.9352215 1.0866873 1.2054667 0.6019289 NCAPH −0.724468606 0.12468513 0.049825082 −7.202682103 4.6820765 3.360637 3.9352215 1.0866873 1.2054667 0.6019289 MTHFR −0.776164694 0.101257001 0.035980101 −7.253714166 11.1831257 10.3931195 11.8248894 8.9661695 1.2054667 8.5419101 RRAGA −0.787612446 0.097014689 0.033562545 −7.498873168 12.2576569 11.3560627 11.1969823 9.8879116 1.2054667 8.4493889 KDM5C −0.760571865 0.107869852 0.039788975 −7.508375245 10.36466 10.4612835 10.3711388 7.4626381 1.2054667 8.6786124 IL32 −0.771855276 0.103179141 0.037053679 −7.555715522 10.0243457 9.9614598 9.3431532 7.6158948 1.2054667 7.0438915 TNKS1BP1 −0.749573581 0.112884449 0.0426013 −7.775239005 9.4044234 8.8620252 9.6366244 7.5413002 6.4455364 0.6019289 DHX9 −0.779507923 0.100080374 0.035306908 −7.793367414 10.503547 10.1752932 10.6357397 7.5413002 1.2054667 8.4493889 XPO1 −0.745018917 0.115280747 0.0438851 −7.877838079 10.7341965 9.7819266 10.637916 8.7513276 7.6601162 0.6019289 RAB14 −0.859602606 0.074257601 0.021363235 −7.97136647 12.2165773 11.9957841 12.002604 9.4820885 9.0077769 0.6019289 MAF1 −0.827690658 0.083401623 0.026094038 −7.972651837 12.0702912 10.8994373 11.3401902 8.3967085 1.2054667 9.0752315 SIRT3 −0.802328843 0.091317418 0.03044933 −8.301227813 12.7304926 12.8797325 12.5081797 9.8264078 9.7484834 8.2221901 PRRX2 −0.739429303 0.1180144 0.045481024 −8.324886536 11.4722934 10.9146078 12.1996331 8.4689236 7.8571772 8.8763623 SRGAP1 −0.830811354 0.082259709 0.02560138 −8.384447916 10.1665236 10.9262977 11.4220281 7.8808129 8.3543123 0.6019289 LRCH1 −0.738456709 0.118223679 0.045842093 −8.422075134 10.8328458 10.8686094 11.6739901 5.9133149 7.7944336 9.1710561 TM4SF1 −0.743323608 0.116287998 0.044383375 −8.453549844 13.8777375 15.0481396 13.513107 8.7430302 10.9881675 11.9685824 FOXQ1 −0.725855612 0.124120257 0.04943593 −8.45924995 4.2634629 3.3213504 4.2859964 1.0866873 1.2054667 0.6019289 ALPP −0.731089651 0.121739156 0.047826366 −8.497462516 10.976053 11.5659833 11.7544238 8.4789512 9.9394149 2.9363609 KHNYN −0.736988199 0.118760034 0.046147797 −8.586415137 10.3007843 10.8210959 10.4599237 7.3578678 9.4216969 0.6019289 SQSTM1 −0.739446201 0.1180144 0.045473 −8.690718017 13.6889506 13.7153851 13.8060905 11.4643999 10.5959097 9.6664224 BTN3A3 −0.803174961 0.091042429 0.030252748 −8.713151242 4.2098819 3.360637 7.2508437 1.0866873 1.2054667 0.6019289 BMP2K −0.777172382 0.1010258 0.035814812 −8.713151242 4.2098819 3.3213504 6.0125266 1.0866873 1.2054667 0.6019289 KIT −0.726517285 0.123806361 0.049249779 −8.713151242 4.2098819 4.3513152 3.3243747 1.0866873 1.2054667 0.6019289 MCM7 −0.730604819 0.122080069 0.048000481 −8.715781982 9.5580365 10.2409561 10.992779 4.8170878 7.5630806 7.8691489 MYO10 −0.749778324 0.112789349 0.042528284 −8.805157925 12.2829797 12.0107639 12.2259124 8.7595777 9.6277013 9.0875635 PRKAA2 −0.769263962 0.104318244 0.03768595 −8.851049717 4.815804 4.3513152 3.9352215 1.6938929 1.2054667 0.6019289 C1orf106 −0.798503734 0.093373222 0.031491615 −8.951910626 3.8399484 6.4291897 3.7641245 1.0866873 1.2054667 0.6019289 MIR3654 −0.792076327 0.095429111 0.032621359 −8.951910626 3.8399484 6.0361098 3.7641245 1.0866873 1.2054667 0.6019289 GALK2 −0.782128639 0.098981747 0.034666613 −8.951910626 5.3285264 3.8720139 3.7641245 1.0866873 1.2054667 0.6019289 MTHFSD −0.767221412 0.10498791 0.038169783 −8.951910626 3.8197323 4.9115166 3.7641245 1.0866873 1.2054667 0.6019289 ATP2A1 −0.766509233 0.105276608 0.038309396 −8.951910626 4.6820765 3.8720139 3.7641245 1.0866873 1.2054667 0.6019289 SLC6A7 −0.765130438 0.105922473 0.038666453 −8.951910626 3.8399484 4.7507076 3.7641245 1.0866873 1.2054667 0.6019289 PRSS36 −0.763012467 0.106907023 0.039254594 −8.951910626 3.8197323 4.7507076 3.7641245 1.0866873 1.2054667 0.6019289 NUDCD1 −0.792600071 0.09520032 0.032527481 −8.994640793 5.4911209 3.7709946 3.9352215 1.0866873 1.2054667 0.6019289 LRRC14 −0.788009239 0.096821537 0.033455829 −8.994640793 5.2636993 3.7709946 3.9352215 1.0866873 1.2054667 0.6019289 KCNQ3 −0.786617204 0.097552701 0.033796839 −8.994640793 5.3285264 3.7709946 3.9083598 1.0866873 1.2054667 0.6019289 NCKIPSD −0.78526516 0.098120682 0.034090508 −8.994640793 5.2636993 3.7709946 3.9083598 1.0866873 1.2054667 0.6019289 LOC729987 −0.784664614 0.098241201 0.034230924 −8.994640793 4.2634629 3.7709946 4.2859964 1.0866873 1.2054667 0.6019289 FAM186B −0.763037456 0.106907023 0.03924657 −8.994640793 3.8197323 3.7709946 4.7244061 1.0866873 1.2054667 0.6019289 PTCH2 −0.758577042 0.109048772 0.040328171 −8.994640793 3.8399484 3.7709946 4.5083337 1.0866873 1.2054667 0.6019289 NEK1 −0.754491245 0.110509614 0.041323116 −8.994640793 3.8197323 3.7709946 4.4498938 1.0866873 1.2054667 0.6019289 GPR176 −0.833023803 0.081679166 0.025192169 −9.042838045 4.2634629 3.7709946 5.9741452 1.0866873 1.2054667 0.6019289 R3HDM1 −0.820485766 0.085658176 0.027313648 −9.042838045 4.2634629 5.3406193 3.7641245 1.0866873 1.2054667 0.6019289 TMEM30B −0.804682097 0.090664228 0.029984755 −9.042838045 4.2634629 7.3033622 3.3243747 1.0866873 1.2054667 0.6019289 TMED10P1 −0.797312014 0.093829277 0.031734735 −9.042838045 4.2634629 3.8720139 4.2859964 1.0866873 1.2054667 0.6019289 TOX3 −0.790781372 0.09572616 0.032833186 −9.042838045 4.2634629 4.4133226 3.7641245 1.0866873 1.2054667 0.6019289 PTPDC1 −0.790781372 0.09572616 0.032833186 −9.042838045 4.2634629 4.4133226 3.7641245 1.0866873 1.2054667 0.6019289 GRM2 −0.767055183 0.105041879 0.038206692 −9.042838045 4.2634629 3.3213504 5.3892653 1.0866873 1.2054667 0.6019289 LACC1 −0.739397345 0.1180144 0.045530771 −9.042838045 4.2634629 3.360637 4.4498938 1.0866873 1.2054667 0.6019289 SPC25 −0.734212844 0.120413206 0.047028003 −9.042838045 4.2634629 3.3213504 4.4498938 1.0866873 1.2054667 0.6019289 KDM2A −0.87790267 0.070255881 0.019579555 −9.068082933 12.4400298 11.9075484 12.3047368 9.3626047 1.2054667 9.1239392 TTC21A −0.811166838 0.088696214 0.028918398 −9.091193323 4.2634629 4.3899364 3.9352215 1.0866873 1.2054667 0.6019289 SURF2 −0.811166838 0.088696214 0.028918398 −9.091193323 4.2634629 4.3899364 3.9352215 1.0866873 1.2054667 0.6019289 PIEZO1 −0.874186213 0.070954628 0.019926181 −9.136868614 10.2640365 10.701797 10.8041137 7.5790795 7.6124139 0.6019289 EIF5AL1 −0.728314847 0.123091778 0.048653615 −9.162475801 14.3208565 15.0502399 14.2244262 11.8545024 10.653026 11.8432763 ATXN7L2 −0.831389503 0.082162426 0.025495467 −9.185187146 5.7530242 3.7709946 4.2859964 1.0866873 1.2054667 0.6019289 C9orf7 −0.831239237 0.082167973 0.025518735 −9.185187146 5.7445127 3.7709946 4.2859964 1.0866873 1.2054667 0.6019289 BROX −0.816627968 0.086956079 0.02799326 −9.185187146 5.0569476 3.7709946 4.2859964 1.0866873 1.2054667 0.6019289 C10orf28 −0.800843559 0.092139422 0.030814411 −9.185187146 3.8399484 4.3899364 4.2859964 1.0866873 1.2054667 0.6019289 LOC283914 −0.800210963 0.092461329 0.030998155 −9.185187146 4.309025 3.8720139 4.2859964 1.0866873 1.2054667 0.6019289 AGTPBP1 −0.772064763 0.103179141 0.037038434 −9.185187146 5.3285264 3.360637 4.2859964 1.0866873 1.2054667 0.6019289 NAT6 −0.748260606 0.113494139 0.042980823 −9.185187146 4.7435639 3.3213504 4.2859964 1.0866873 1.2054667 0.6019289 ZNRF1 −0.75223209 0.111864532 0.041944957 −9.222639568 10.2490712 9.1736173 10.6270014 8.2982105 1.2054667 7.0438915 WDR45 −0.804439806 0.090692834 0.030032095 −9.232325976 11.6317494 11.0672144 10.9653115 6.8092213 8.4250552 8.0813159 ZNF771 −0.8507148 0.07656248 0.022555564 −9.239763602 4.2634629 4.4133226 4.2859964 1.0866873 1.2054667 0.6019289 C11orf83 −0.8507148 0.07656248 0.022555564 −9.239763602 4.2634629 4.4133226 4.2859964 1.0866873 1.2054667 0.6019289 CYP27C1 −0.802090153 0.091443132 0.030506299 −9.239763602 3.8399484 4.4133226 4.2859964 1.0866873 1.2054667 0.6019289 LIN9 −0.799498689 0.092882057 0.031188317 −9.239763602 3.8197323 4.4133226 4.2859964 1.0866873 1.2054667 0.6019289 LOC100129931 −0.799498689 0.092882057 0.031188317 −9.239763602 3.8197323 4.4133226 4.2859964 1.0866873 1.2054667 0.6019289 PCSK7 −0.793828215 0.094750565 0.032249057 −9.239763602 4.309025 4.4133226 3.7641245 1.0866873 1.2054667 0.6019289 LOC100506085 −0.770675867 0.103610875 0.037328091 −9.239763602 4.7435639 4.4133226 3.9352215 1.6938929 1.2054667 0.6019289 RNF207 −0.767532302 0.104951556 0.03809115 −9.239763602 3.8197323 4.4133226 3.9083598 1.0866873 1.2054667 0.6019289 TAF10 −0.879195745 0.069835403 0.019316376 −9.251870263 11.485123 11.6255857 11.3159291 8.2753779 8.7007207 0.6019289 LMTK2 −0.784148926 0.098241201 0.034302335 −9.257801408 9.6520508 9.7782453 9.8655896 6.5675757 7.9750285 0.6019289 MAPKAPK2 −0.73941682 0.1180144 0.045489048 −9.260909792 12.9100916 12.5322853 13.4282613 10.6746346 8.8826529 9.6989376 G3BP1 −0.815129278 0.087351733 0.02825002 −9.27360905 10.6682266 10.7114808 11.3810399 8.167909 6.7399276 7.5147138 LTC4S −0.797878356 0.093671851 0.03163524 −9.303692426 3.8197323 5.4876732 3.9352215 1.0866873 1.2054667 0.6019289 MYEOV −0.796860401 0.093970965 0.031798122 −9.303692426 3.8197323 5.4346801 3.9352215 1.0866873 1.2054667 0.6019289 FER1L6-AS1 −0.792917894 0.095066463 0.032450453 −9.303692426 3.8197323 3.8720139 5.5715986 1.0866873 1.2054667 0.6019289 TSPAN15 −0.782665528 0.098744651 0.034551071 −9.303692426 3.8197323 4.9115166 3.9083598 1.0866873 1.2054667 0.6019289 SNORA80B −0.780004099 0.099902938 0.035170505 −9.303692426 3.8197323 4.8079702 3.9083598 1.0866873 1.2054667 0.6019289 CENPC1 −0.773908381 0.10250508 0.036609163 −9.303692426 3.8197323 3.8720139 4.7244061 1.0866873 1.2054667 0.6019289 LOC283731 −0.73447351 0.120231025 0.046917275 −9.303692426 3.8197323 4.8079702 5.5715986 1.0866873 2.5373444 0.6019289 HNRNPH3 −0.754327813 0.110613279 0.041380085 −9.31923649 11.7356106 10.4817994 12.9194344 9.6992226 9.4007863 0.6019289 SYNGR3 −0.837865016 0.079970163 0.024401829 −9.33297891 4.309025 3.7709946 6.0125266 1.0866873 1.2054667 0.6019289 USP48 −0.815471908 0.087217212 0.028169783 −9.33297891 4.309025 3.7709946 4.9444683 1.0866873 1.2054667 0.6019289 FOXD1 −0.790833907 0.09572616 0.032806708 −9.33297891 4.309025 3.360637 6.0560619 1.0866873 1.2054667 0.6019289 SRGAP3 −0.775491546 0.101477705 0.036125331 −9.33297891 4.309025 3.360637 5.3892653 1.0866873 1.2054667 0.6019289 MLLT3 −0.77062067 0.103668192 0.037365803 −9.33297891 4.309025 3.3213504 5.3892653 1.0866873 1.2054667 0.6019289 LOC100616668 −0.766030864 0.105517102 0.038449009 −9.33297891 4.309025 3.3213504 5.2252164 1.0866873 1.2054667 0.6019289 INVS −0.739762121 0.1179053 0.045388751 −9.33297891 4.309025 3.3213504 4.5083337 1.0866873 1.2054667 0.6019289 COMTD1 −0.72911852 0.122887691 0.048439381 −9.33297891 4.309025 5.3406193 2.9956812 1.0866873 1.2054667 0.6019289 PPARD −0.881850378 0.069378792 0.019034743 −9.350778557 10.6905534 11.5004644 10.9791106 8.2753779 7.7728978 0.6019289 SECISBP2 −0.791727626 0.095488356 0.032688759 −9.403108955 11.4787224 10.8210959 10.4672856 1.0866873 7.5879581 9.2278676 SERPINA1 −0.821407486 0.085414368 0.027171628 −9.434980403 3.8399484 4.9115166 4.2859964 1.0866873 1.2054667 0.6019289 COL11A2 −0.78805069 0.096788354 0.033420525 −9.434980403 3.8399484 3.8720139 5.2176156 1.0866873 1.2054667 0.6019289 GAGE1 −0.776976992 0.101087509 0.035853326 −9.434980403 3.8399484 3.8720139 4.7549172 1.0866873 1.2054667 0.6019289 SLC36A2 −0.769455295 0.104268882 0.037633796 −9.434980403 3.8399484 3.8720139 4.5083337 1.0866873 1.2054667 0.6019289 FLJ31662 −0.769455295 0.104268882 0.037633796 −9.434980403 3.8399484 3.8720139 4.5083337 1.0866873 1.2054667 0.6019289 MLLT11 −0.767397147 0.104951556 0.038131269 −9.434980403 3.8399484 3.8720139 4.4498938 1.0866873 1.2054667 0.6019289 B3GAT3 −0.852203623 0.075942035 0.02226029 −9.47805185 9.8828584 9.6947857 9.1431787 6.4501951 6.8672984 0.6019289 PARP10 −0.746564495 0.11442898 0.043485517 −9.517364112 10.2415299 9.6711603 10.862976 6.0805901 7.6124139 7.3606902 TUBB4B −0.740204167 0.117838959 0.045265185 −9.540072622 13.3137451 14.69107 14.7436225 10.1009363 12.3033305 10.0597448 TAF1L −0.863423848 0.07316741 0.020881008 −9.610609518 4.309025 4.3513152 4.4498938 1.0866873 1.2054667 0.6019289 TRNT1 −0.827914627 0.083196626 0.026016208 −9.610609518 3.8399484 4.3513152 4.9444683 1.0866873 1.2054667 0.6019289 E2F6 −0.785925601 0.097841721 0.033945278 −9.610609518 3.3509967 4.3513152 5.7236017 1.0866873 1.2054667 0.6019289 WDR3 −0.772568008 0.102979156 0.036914066 −9.610609518 5.3285264 4.3513152 3.3243747 1.0866873 1.2054667 0.6019289 RASA2 −0.756979468 0.109559231 0.040697264 −9.610609518 3.3509967 4.3513152 4.7549172 1.0866873 1.2054667 0.6019289 FANCG −0.728137258 0.123231261 0.048737062 −9.610609518 2.993831 4.3513152 5.2252164 1.0866873 1.2054667 0.6019289 KLHL6 −0.845095305 0.077962917 0.023263259 −9.647030648 4.2098819 3.8720139 6.3692392 1.0866873 1.2054667 0.6019289 UBE2Q2P3 −0.844914243 0.07804894 0.023301773 −9.647030648 4.2098819 3.8720139 6.3558005 1.0866873 1.2054667 0.6019289 PARP2 −0.835041567 0.080994735 0.024866405 −9.647030648 5.3044627 3.8720139 4.2859964 1.0866873 1.2054667 0.6019289 TMEM198 −0.832250094 0.082026528 0.025339806 −9.647030648 7.4456083 3.8720139 3.9352215 1.0866873 1.2054667 0.6019289 MED27 −0.829383499 0.082893908 0.025826045 −9.647030648 5.0569476 3.8720139 4.2859964 1.0866873 1.2054667 0.6019289 KIAA1432 −0.789716433 0.096100137 0.033008906 −9.647030648 4.963444 3.8720139 3.9083598 1.0866873 1.2054667 0.6019289 ARID3B −0.785124382 0.098161941 0.034120998 −9.647030648 4.6820765 3.8720139 3.9352215 1.0866873 1.2054667 0.6019289 PRRC2A −0.898664265 0.066663913 0.017261494 −9.647676821 11.9466566 12.2179049 12.0806774 9.1655971 8.8104958 0.6019289 IL10 −0.810799926 0.088793079 0.028985798 −9.740486084 6.7078705 6.537655 7.481604 4.1976103 3.9031434 0.6019289 ESYT1 −0.846231458 0.077708686 0.023072294 −9.77324712 11.0266571 10.2516151 9.7696066 7.7378191 7.2567201 0.6019289 ISM2 −0.815470463 0.087217212 0.028177806 −9.868747668 3.8399484 4.4133226 4.5083337 1.0866873 1.2054667 0.6019289 FANCA −0.851312069 0.076234421 0.02240873 −9.871361236 3.8197323 4.3899364 6.0316576 1.0866873 1.2054667 0.6019289 NR2C2 −0.845934009 0.077792812 0.023135682 −9.871361236 3.8399484 4.3899364 5.5715986 1.0866873 1.2054667 0.6019289 PPEF2 −0.839746665 0.079317736 0.024080077 −9.871361236 3.8197323 4.3899364 5.3892653 1.0866873 1.2054667 0.6019289 TMEM229B −0.831520299 0.082162426 0.025448126 −9.871361236 5.3354128 4.3899364 3.7641245 1.0866873 1.2054667 0.6019289 BEND7 −0.822024598 0.085361525 0.027098612 −9.871361236 3.8197323 4.3899364 4.7549172 1.0866873 1.2054667 0.6019289 NIF3L1 −0.800318964 0.092410962 0.03096606 −9.871361236 6.4179694 4.3899364 3.3243747 1.0866873 1.2054667 0.6019289 BNC1 −0.795394566 0.094440529 0.032049266 −9.871361236 3.3509967 4.3899364 6.0125266 1.0866873 1.2054667 0.6019289 TCF7 −0.775597441 0.101475033 0.036107679 −9.871361236 3.3509967 4.3899364 5.2176156 1.0866873 1.2054667 0.6019289 WNT1 −0.765288866 0.105844907 0.038620717 −9.871361236 3.0245043 4.3899364 6.3692392 1.0866873 1.2054667 0.6019289 MAPK13 −0.755515067 0.110198518 0.041050309 −9.871361236 4.7435639 4.3899364 3.3243747 1.0866873 1.2054667 0.6019289 TSPAN18 −0.752933419 0.111491357 0.04176362 −9.871361236 4.6820765 4.3899364 3.3243747 1.0866873 1.2054667 0.6019289 GLYCTK −0.871376681 0.071618584 0.020215037 −9.893156366 6.7928648 4.3899364 3.9083598 1.0866873 1.2054667 0.6019289 TMEM38B −0.859759036 0.074257601 0.021339164 −9.893156366 5.8972917 4.3899364 3.9083598 1.0866873 1.2054667 0.6019289 ZDHHC24 −0.852874223 0.075772552 0.02218567 −9.893156366 5.4911209 4.3899364 3.9083598 1.0866873 1.2054667 0.6019289 PLCH2 −0.835056527 0.080994735 0.024850357 −9.893156366 4.2634629 5.1957839 3.9083598 1.0866873 1.2054667 0.6019289 ZBTB25 −0.826240556 0.083957582 0.026406162 −9.893156366 4.6394091 4.3513152 3.9083598 1.0866873 1.2054667 0.6019289 MRTO4 −0.84869977 0.077242351 0.022806708 −9.904732109 11.0570484 11.7052908 10.5574232 8.180253 8.3971729 0.6019289 ERLIN1 −0.783442968 0.098499754 0.03444917 −9.914684253 11.7048641 11.2350596 11.7483934 7.9254928 8.8624022 8.3299138 CSF1 −0.824689172 0.084515403 0.026637246 −9.959991289 13.0125994 12.3595162 13.0534609 9.7373165 9.7206295 8.577319 TMEM136 −0.83776017 0.080029549 0.024433122 −10.03268119 4.815804 4.4133226 3.9083598 1.0866873 1.2054667 0.6019289 CPSF3 −0.831802362 0.082115651 0.025394367 −10.03268119 5.2636993 4.4133226 3.7641245 1.0866873 1.2054667 0.6019289 FKBP1B −0.830817699 0.082259709 0.025593356 −10.03268119 4.6394091 4.4133226 3.9083598 1.0866873 1.2054667 0.6019289 DOCK4 −0.787739558 0.096975009 0.033532857 −10.03268119 3.3509967 4.4133226 5.5969865 1.0866873 1.2054667 0.6019289 FGF17 −0.7773037 0.1010258 0.035798764 −10.03268119 3.3509967 4.4133226 5.2176156 1.0866873 1.2054667 0.6019289 LMNB1 −0.743999802 0.115827669 0.044131429 −10.03268119 2.993831 4.4133226 5.5969865 1.0866873 1.2054667 0.6019289 TOMM40L −0.741090637 0.11759359 0.045036508 −10.03268119 5.4911209 4.4133226 2.9956812 1.0866873 1.2054667 0.6019289 KAZN −0.838725782 0.07961428 0.02426703 −10.06621054 10.5285503 10.6643939 9.6963177 7.1971015 7.7944336 0.6019289 WASF3 −0.871844424 0.071557972 0.020178127 −10.07908406 6.8989234 4.3513152 3.9352215 1.0866873 1.2054667 0.6019289 OSGIN1 −0.855121163 0.075307325 0.021979459 −10.07908406 5.3285264 4.4133226 3.9352215 1.0866873 1.2054667 0.6019289 LOC401164 −0.853867831 0.075521779 0.022099815 −10.07908406 4.309025 5.8096013 3.9352215 1.0866873 1.2054667 0.6019289 MMEL1 −0.841739307 0.078901035 0.023755918 −10.07908406 4.2634629 5.3621423 3.9352215 1.0866873 1.2054667 0.6019289 IMP4 −0.833112659 0.081670717 0.025176121 −10.07908406 4.309025 4.8304956 3.9352215 1.0866873 1.2054667 0.6019289 KCNRG −0.831442613 0.082162426 0.025475407 −10.07908406 4.6820765 4.3513152 3.9352215 1.0866873 1.2054667 0.6019289 GNRHR2 −0.831442613 0.082162426 0.025475407 −10.07908406 4.6820765 4.3513152 3.9352215 1.0866873 1.2054667 0.6019289 FAM212A −0.831412674 0.082162426 0.025487443 −10.07908406 4.2634629 4.9115166 3.9352215 1.0866873 1.2054667 0.6019289 FOXP3 −0.830494188 0.08237599 0.025651127 −10.07908406 4.309025 4.7507076 3.9352215 1.0866873 1.2054667 0.6019289 IL17RC −0.829072426 0.082927362 0.025850116 −10.07908406 4.2634629 4.8304956 3.9352215 1.0866873 1.2054667 0.6019289 SLC16A12 −0.826552837 0.083748845 0.026326727 −10.07908406 4.2634629 4.7507076 3.9352215 1.0866873 1.2054667 0.6019289 XRCC3 −0.824141777 0.084705069 0.026752788 −10.07908406 4.2098819 4.8304956 3.9352215 1.0866873 1.2054667 0.6019289 RPP30 −0.727957261 0.123245219 0.048823718 −10.07908406 4.6394091 5.4346801 3.9352215 1.0866873 2.5373444 0.6019289 FAM3A −0.834979721 0.080994735 0.024874428 −10.14075402 11.0599097 10.0526605 9.9555834 6.7105675 8.3687411 0.6019289 PAWR −0.728308719 0.123091778 0.048661638 −10.24215848 7.7590076 10.2030168 9.0805542 5.7241063 7.6601162 0.6019289 MAP4K4 −0.79879715 0.093160485 0.031339164 −10.28043139 12.1933119 12.0997301 12.5549978 9.6644958 8.831483 8.4106527 GMDS −0.856826964 0.074799231 0.021691407 −10.29025241 3.8197323 6.0361098 4.4498938 1.0866873 1.2054667 0.6019289 TMEM169 −0.808651446 0.089424388 0.029332424 −10.29025241 6.3818471 3.360637 4.4498938 1.0866873 1.2054667 0.6019289 PIK3C2B −0.772692948 0.102923446 0.036877156 −10.29025241 4.963444 3.360637 4.4498938 1.0866873 1.2054667 0.6019289 ST3GAL1 −0.824654588 0.084580705 0.026671748 −10.3055564 11.4108658 11.9718106 12.6518667 10.1582229 8.6064601 0.6019289 DAZAP2 −0.855274416 0.075282272 0.021955388 −10.36456829 13.870218 13.016869 12.862876 9.8765776 9.4892879 9.8799953 AKIRIN2 −0.89622438 0.066907118 0.017544732 −10.46571833 11.2447766 11.22833 11.79692 8.5848861 7.8571772 2.9363609 HIVEP2 −0.856950919 0.074758653 0.021667335 −10.60698699 10.36466 11.1132349 11.4765505 8.4889095 7.7062919 0.6019289 PRSS21 −0.893989691 0.067225527 0.017730883 −10.71564202 3.8399484 8.9099134 4.5083337 1.0866873 1.2054667 0.6019289 RHPN1 −0.837017112 0.080350378 0.024575945 −10.71564202 4.7435639 3.8720139 4.5083337 1.0866873 1.2054667 0.6019289 NUDT15 −0.769089119 0.1044167 0.037782235 −10.71564202 3.3509967 4.8079702 4.5083337 1.0866873 1.2054667 0.6019289 MPHOSPH9 −0.767619169 0.104951556 0.038067079 −10.71564202 4.7435639 3.360637 4.5083337 1.0866873 1.2054667 0.6019289 ELMO1 −0.76485949 0.106046107 0.038729038 −10.71564202 4.6820765 3.360637 4.5083337 1.0866873 1.2054667 0.6019289 ANKRD11 −0.779956837 0.099902938 0.035186552 −10.74746309 12.1266449 12.4918369 12.3285117 9.7825497 8.7007207 8.8476482 LOC339524 −0.894728733 0.067157603 0.017662682 −10.8073613 4.6394091 4.4133226 4.4498938 1.0866873 1.2054667 0.6019289 SUV39H1 −0.894728733 0.067157603 0.017662682 −10.8073613 4.6394091 4.4133226 4.4498938 1.0866873 1.2054667 0.6019289 SYN1 −0.902520879 0.065854333 0.016897216 −11.13175989 4.6820765 4.4133226 4.5083337 1.0866873 1.2054667 0.6019289 NES −0.758396098 0.109168569 0.040408409 −11.18458928 11.3490472 13.189984 13.1850455 7.8656068 9.1398349 10.1329672 MRPL32 −0.88238114 0.069332647 0.019010672 −11.22155263 11.7048641 12.2823483 12.0076619 8.2166637 8.3397377 8.833074 PDIA3 −0.775006043 0.101834075 0.036268956 −11.25375614 7.4279993 6.270596 6.0125266 4.5400907 1.2054667 2.7782613 ECM1 −0.918277657 0.063260715 0.015627858 −11.28216207 10.8691867 10.2329098 10.4843186 6.988347 7.5120008 0.6019289 HLA-B −0.886920836 0.068365464 0.018485116 −11.36234947 16.466846 16.263629 15.9959348 12.1313726 12.8596921 12.9606567 UBE2J1 −0.891892727 0.067604226 0.017980422 −11.43569008 12.1550212 11.1161542 11.0280543 8.6395496 8.0305306 0.6019289 LOC100628307 −0.872785081 0.071297709 0.020065795 −11.46321176 4.2098819 4.4133226 4.7244061 1.0866873 1.2054667 0.6019289 PSMB2 −0.864922686 0.072798529 0.02073979 −11.49048458 12.837747 12.6099312 11.3308037 9.5924293 1.2054667 9.0875635 WHSC2 −0.876489201 0.070539978 0.019748054 −11.56040292 4.2098819 4.7365865 4.4498938 1.0866873 1.2054667 0.6019289 PAQR5 −0.816320908 0.086958113 0.028041403 −11.56040292 5.3162271 4.7365865 3.9083598 1.6938929 1.2054667 0.6019289 RGS12 −0.85632049 0.074889306 0.02176683 −11.61300118 9.8065464 10.6341645 10.8814627 7.0964955 7.956043 0.6019289 CENPL −0.844281161 0.078284823 0.023423734 −11.61644899 4.7435639 4.9115166 4.2859964 1.6938929 1.2054667 0.6019289 METTL11A −0.740936492 0.117655882 0.045099093 −11.65975483 10.2565732 9.7256961 9.7252629 6.1822306 1.2054667 8.932131 LOC388588 −0.843083808 0.078689412 0.023640376 −11.6741118 3.8197323 4.7507076 4.7244061 1.0866873 1.2054667 0.6019289 NOL9 −0.836326587 0.080597949 0.024699511 −11.6741118 4.7435639 4.7507076 3.7641245 1.0866873 1.2054667 0.6019289 HIPK2 −0.806974555 0.090048446 0.029596405 −11.69279133 11.5858346 10.4287786 9.3107812 8.0382872 7.5630806 0.6019289 HYAL4 −0.844676871 0.078078462 0.023323437 −11.70822562 3.8197323 4.7507076 4.7549172 1.0866873 1.2054667 0.6019289 LOC284551 −0.843940366 0.078442556 0.02349675 −11.70822562 3.8197323 4.7365865 4.7549172 1.0866873 1.2054667 0.6019289 DUSP11 −0.837499289 0.080186061 0.024494103 −11.70822562 4.7435639 3.7709946 4.7549172 1.0866873 1.2054667 0.6019289 C12orf59 −0.912981555 0.064158575 0.016018615 −11.73480352 4.6394091 4.3899364 4.7244061 1.0866873 1.2054667 0.6019289 AP1S3 −0.909991271 0.064756039 0.016359624 −11.73480352 4.6394091 4.3513152 4.7549172 1.0866873 1.2054667 0.6019289 TMEM108 −0.869893387 0.071778384 0.020346626 −11.73480352 4.6394091 5.297868 3.9083598 1.0866873 1.2054667 0.6019289 TMCO6 −0.858233419 0.07443975 0.021498034 −11.73480352 4.6394091 3.7709946 5.5715986 1.0866873 1.2054667 0.6019289 BARX2 −0.85163589 0.076222506 0.022384659 −11.73480352 4.6394091 5.3406193 3.7641245 1.0866873 1.2054667 0.6019289 ADORA3 −0.805634209 0.090331212 0.029778544 −11.73480352 4.6394091 3.360637 5.5969865 1.0866873 1.2054667 0.6019289 PLEKHN1 −0.774750635 0.101915392 0.036314691 −11.73480352 4.6394091 6.1390574 2.9956812 1.0866873 1.2054667 0.6019289 ARHGEF16 −0.730806987 0.122051571 0.047969189 −11.73480352 4.6394091 4.8304956 2.9956812 1.0866873 1.2054667 0.6019289 NOTCH2 −0.8151801 0.087291954 0.02821632 −12.00940689 10.7852289 12.0162438 12.2964944 9.7077753 1.2054667 8.4301508 GLO1 −0.890477608 0.067913831 0.018147316 −12.0679301 13.2352334 13.0378039 11.663346 9.690619 1.2054667 9.4446975 DSP −0.908820827 0.065023856 0.016448688 −12.08704063 4.6820765 7.6317881 3.9352215 1.0866873 1.2054667 0.6019289 SENP7 −0.884133097 0.068843868 0.018786007 −12.08704063 4.6820765 3.8720139 6.0721689 1.0866873 1.2054667 0.6019289 PUS7 −0.809142718 0.08931343 0.029266629 −12.08704063 4.6820765 5.7897017 3.3243747 1.0866873 1.2054667 0.6019289 IGSF21 −0.773209859 0.102731018 0.036775255 −12.08704063 4.6820765 2.8096013 6.861515 1.0866873 1.2054667 0.6019289 LOC285965 −0.885841557 0.068486123 0.018609484 −12.14679241 4.2634629 4.8079702 4.4498938 1.0866873 1.2054667 0.6019289 LEAP2 −0.885841557 0.068486123 0.018609484 −12.14679241 4.2634629 4.8079702 4.4498938 1.0866873 1.2054667 0.6019289 KIAA0391 −0.839162193 0.079358501 0.024149884 −12.14679241 4.7435639 4.8079702 3.7641245 1.0866873 1.2054667 0.6019289 PKP2 −0.920126875 0.062956691 0.015480221 −12.19276133 4.2098819 7.3437697 4.5083337 1.0866873 1.2054667 0.6019289 LRRC1 −0.912519193 0.064224388 0.016058734 −12.19276133 4.2098819 6.3911446 4.5083337 1.0866873 1.2054667 0.6019289 HLA-DOB −0.897978406 0.066685485 0.017300008 −12.19276133 4.2098819 4.7365865 4.7549172 1.0866873 1.2054667 0.6019289 CIDEB −0.897026531 0.066827455 0.017438819 −12.19276133 4.2098819 4.7507076 4.7244061 1.0866873 1.2054667 0.6019289 ZSCAN12P1 −0.891088835 0.067801994 0.018091952 −12.19276133 4.2098819 4.3899364 5.5929159 1.0866873 1.2054667 0.6019289 RAD52 −0.88039878 0.069612081 0.01918238 −12.19276133 4.2098819 4.4133226 4.9444683 1.0866873 1.2054667 0.6019289 C10orf6 −0.880133946 0.069663629 0.01921608 −12.19276133 4.2098819 4.8304956 4.4498938 1.0866873 1.2054667 0.6019289 PEX13 −0.87845895 0.070105249 0.019464816 −12.19276133 4.2098819 5.4876732 4.2859964 1.0866873 1.2054667 0.6019289 PANK3 −0.878124667 0.070226005 0.019533018 −12.19276133 4.2098819 4.3899364 4.9444683 1.0866873 1.2054667 0.6019289 CNGB1 −0.906468901 0.065320795 0.01664206 −12.21292904 4.815804 4.3899364 4.5083337 1.0866873 1.2054667 0.6019289 CPLX1 −0.860132739 0.073977368 0.021246088 −12.21292904 4.815804 4.7507076 3.9083598 1.0866873 1.2054667 0.6019289 JRKL −0.77765297 0.100926453 0.035705689 −12.21292904 4.815804 3.3213504 4.7244061 1.0866873 1.2054667 0.6019289 NFATC2IP −0.826832706 0.083627111 0.026260932 −12.31491054 5.3162271 4.3513152 4.2859964 1.6938929 1.2054667 0.6019289 BPGM −0.936238501 0.0607352 0.014274252 −12.33793384 4.6820765 4.8304956 4.5083337 1.0866873 1.2054667 0.6019289 SPDEF −0.844040402 0.078399915 0.023471074 −12.33793384 4.815804 4.8304956 3.7641245 1.0866873 1.2054667 0.6019289 CDK7 −0.840233259 0.079229335 0.024006259 −12.33793384 4.7435639 4.8304956 3.7641245 1.0866873 1.2054667 0.6019289 ZYG11A −0.740624937 0.117680421 0.045147236 −12.33793384 3.0245043 4.8304956 4.7549172 1.0866873 1.2054667 0.6019289 PSORS1C3 −0.739937177 0.117838959 0.045343818 −12.33793384 4.815804 4.8304956 2.9956812 1.0866873 1.2054667 0.6019289 OSCP1 −0.948693574 0.059219172 0.013383616 −12.4469363 4.6394091 4.7507076 4.7244061 1.0866873 1.2054667 0.6019289 KLRD1 −0.919274002 0.06311711 0.01555083 −12.4469363 4.815804 4.3513152 4.7244061 1.0866873 1.2054667 0.6019289 GGT8P −0.88099657 0.069560685 0.019118992 −12.4469363 5.7003762 3.8720139 4.7244061 1.0866873 1.2054667 0.6019289 SRCRB4D −0.859480022 0.074270892 0.021379283 −12.4469363 3.8197323 5.1480825 4.7244061 1.0866873 1.2054667 0.6019289 TMEM180 −0.758472976 0.109154239 0.04038514 −12.4469363 3.0245043 5.297868 4.7244061 1.0866873 1.2054667 0.6019289 LMAN2L −0.78123052 0.099549317 0.034906523 −12.52486855 9.7790278 9.6947857 9.8655896 6.1323043 1.2054667 8.2877844 ZNF395 −0.880010734 0.069702623 0.019241756 −12.5252262 12.2223355 10.4051041 10.2340031 8.5755707 7.0925914 0.6019289 MIR600HG −0.934934554 0.060960411 0.014375351 −12.552468 4.2098819 4.7365865 6.4105447 1.0866873 1.2054667 0.6019289 LOC100287036 −0.798413914 0.093373222 0.031503651 −12.552468 5.3044627 4.7365865 3.3243747 1.0866873 1.2054667 0.6019289 ACAD9 −0.798413914 0.093373222 0.031503651 −12.552468 5.3044627 4.7365865 3.3243747 1.0866873 1.2054667 0.6019289 ASB7 −0.785341092 0.098120682 0.03407446 −12.552468 4.963444 4.7365865 3.3243747 1.0866873 1.2054667 0.6019289 GRK4 −0.782157826 0.098981747 0.034658589 −12.552468 2.993831 4.7365865 6.1759311 1.0866873 1.2054667 0.6019289 C4orf48 −0.769100631 0.1044167 0.037774212 −12.552468 5.7003762 4.7365865 2.9956812 1.0866873 1.2054667 0.6019289 C9orf69 −0.959604504 0.058066829 0.012826767 −12.6133237 4.7435639 4.7365865 4.7549172 1.0866873 1.2054667 0.6019289 KRTCAP3 −0.896768841 0.066883613 0.017480542 −12.6133237 4.7435639 6.0361098 3.9352215 1.0866873 1.2054667 0.6019289 KCNK1 −0.857882763 0.074452862 0.0215542 −12.6133237 4.7435639 5.297868 3.7641245 1.0866873 1.2054667 0.6019289 FAM189A2 −0.843312966 0.078689412 0.023609885 −12.6133237 4.7435639 7.3237074 3.3243747 1.0866873 1.2054667 0.6019289 DCP1B −0.806172723 0.090230223 0.029730402 −12.6133237 4.7435639 3.3213504 5.5446534 1.0866873 1.2054667 0.6019289 PRDX6 −0.831630078 0.082162426 0.025440103 −12.63026134 14.5181455 13.702332 14.1130677 11.5079002 10.4542551 9.32481 DCK −0.91038203 0.064737869 0.016320308 −12.65410906 4.2634629 4.8304956 4.7549172 1.0866873 1.2054667 0.6019289 LOC285456 −0.886537401 0.068460049 0.01855733 −12.65410906 4.2634629 4.3899364 5.018694 1.0866873 1.2054667 0.6019289 GPC2 −0.883677564 0.068960631 0.018840568 −12.65410906 4.2634629 5.4346801 4.2859964 1.0866873 1.2054667 0.6019289 POLR2H −0.854594887 0.075433888 0.022041242 −12.65848286 9.892521 10.0708307 9.5788924 6.2304884 7.5879581 0.6019289 C9orf9 −0.939304704 0.060301826 0.014063227 −12.6759349 4.2634629 4.7507076 6.0540376 1.0866873 1.2054667 0.6019289 GDPD3 −0.927752976 0.061660694 0.014897697 −12.6759349 4.2098819 4.7507076 5.7029118 1.0866873 1.2054667 0.6019289 HLA-DOA −0.925044742 0.061862376 0.015068603 −12.6759349 4.2634629 4.7507076 5.2252164 1.0866873 1.2054667 0.6019289 NRON −0.915440474 0.063593959 0.015804381 −12.6759349 4.2634629 4.7507076 4.9444683 1.0866873 1.2054667 0.6019289 PADI2 −0.915440474 0.063593959 0.015804381 −12.6759349 4.2634629 4.7507076 4.9444683 1.0866873 1.2054667 0.6019289 FAM120C −0.897628097 0.066707952 0.017357779 −12.6759349 3.8399484 4.7507076 6.9482372 1.0866873 1.2054667 0.6019289 LOC650368 −0.891607202 0.067647212 0.018006098 −12.6759349 5.8972917 4.7507076 3.9083598 1.0866873 1.2054667 0.6019289 GRPEL2 −0.870351383 0.071746883 0.020298484 −12.6759349 5.0569476 4.7507076 3.9083598 1.0866873 1.2054667 0.6019289 PIK3CG −0.771773186 0.10321674 0.037084169 −12.6759349 4.309025 4.7507076 5.3892653 1.0866873 2.5373444 0.6019289 LOC100506746 −0.888404792 0.068142722 0.018354329 −12.71297622 6.8201191 3.7709946 4.7549172 1.0866873 1.2054667 0.6019289 HBA1 −0.795136179 0.094440529 0.032073337 −12.71297622 5.0569476 3.360637 4.7549172 1.0866873 1.2054667 0.6019289 DUOX2 −0.779733164 0.099997455 0.035236299 −12.71297622 2.993831 6.0361098 4.7549172 1.0866873 1.2054667 0.6019289 BSPRY −0.763131727 0.106854219 0.039200032 −12.71297622 2.993831 5.4876732 4.7549172 1.0866873 1.2054667 0.6019289 C3orf70 −0.734549997 0.120170675 0.046873947 −12.71297622 5.3354128 2.8096013 4.7549172 1.0866873 1.2054667 0.6019289 ABL1 −0.858010142 0.07443975 0.021538153 −12.80884394 13.4222343 12.9804873 13.2075656 10.6370662 6.9463683 9.5284972 C1orf130 −0.942275574 0.059921626 0.013856214 −12.85330548 4.6820765 6.8774542 4.2859964 1.0866873 1.2054667 0.6019289 KIAA0226L −0.934761475 0.060960411 0.014391399 −12.85330548 4.6394091 6.4291897 4.2859964 1.0866873 1.2054667 0.6019289 LOC728342 −0.929508507 0.061440918 0.014763701 −12.85330548 5.3285264 4.7365865 4.2859964 1.0866873 1.2054667 0.6019289 ANO6 −0.871677277 0.071557972 0.020186151 −12.90661826 9.0659928 9.4437316 9.2664566 6.8092213 5.5764175 0.6019289 KIAA0368 −0.930883897 0.061288269 0.014686673 −12.92961805 11.2990651 11.5182291 12.0613488 8.2285993 8.3687411 0.6019289 RPL9 −0.878805649 0.069923269 0.01937174 −12.93422083 16.3882771 17.3519057 16.8579231 12.6951559 13.5064231 13.481798 BCAR1 −0.833396415 0.081552171 0.025112734 −12.95946304 10.2665157 11.1306625 10.7885254 6.2304884 7.0925914 8.0311264 PRLR −0.972502034 0.056976583 0.012094199 −13.05065106 4.7435639 4.9115166 4.7549172 1.0866873 1.2054667 0.6019289 B3GALT4 −0.945420587 0.059597087 0.013641178 −13.05065106 4.7435639 4.9115166 4.5083337 1.0866873 1.2054667 0.6019289 AKR7A3 −0.940283633 0.060114874 0.013991816 −13.05065106 4.6820765 4.9115166 4.5083337 1.0866873 1.2054667 0.6019289 ITK −0.954988566 0.05844483 0.013024151 −13.06011811 4.309025 4.7507076 7.5008617 1.0866873 1.2054667 0.6019289 S100A13 −0.936482812 0.060682102 0.014243762 −13.06011811 4.309025 5.4346801 4.7549172 1.0866873 1.2054667 0.6019289 QDPR −0.920616954 0.062815622 0.015416834 −13.06011811 4.309025 4.7365865 4.9444683 1.0866873 1.2054667 0.6019289 NKX3-1 −0.918694632 0.063231386 0.015602182 −13.06011811 4.309025 6.5023977 4.4498938 1.0866873 1.2054667 0.6019289 PDE12 −0.911163958 0.06461959 0.016232047 −13.06011811 4.309025 5.3406193 4.5083337 1.0866873 1.2054667 0.6019289 LOC286184 −0.907179176 0.065205844 0.016569847 −13.06011811 4.309025 5.1480825 4.5083337 1.0866873 1.2054667 0.6019289 SERPINC1 −0.894316682 0.067193151 0.017697184 −13.06011811 4.309025 4.4133226 5.018694 1.0866873 1.2054667 0.6019289 TRAF7 −0.926313084 0.061745969 0.014999599 −13.11118079 11.503105 11.3006838 10.4599237 7.9400838 7.5879581 0.6019289 SMAD6 −0.938047619 0.060391495 0.014133836 −13.18917896 4.2634629 4.8079702 5.5929159 1.0866873 1.2054667 0.6019289 RHBDL1 −0.937823607 0.060554615 0.014181979 −13.18917896 4.2098819 4.8079702 6.0560619 1.0866873 1.2054667 0.6019289 RAB17 −0.933771022 0.061000896 0.014469229 −13.18917896 5.2636993 4.8079702 4.2859964 1.0866873 1.2054667 0.6019289 TNIK −0.930914053 0.061288269 0.014678649 −13.18917896 4.2098819 4.8079702 5.5969865 1.0866873 1.2054667 0.6019289 WDR46 −0.897053947 0.066827455 0.017423574 −13.18917896 5.7530242 4.8079702 3.9352215 1.0866873 1.2054667 0.6019289 SNX4 −0.896883849 0.066827455 0.017454866 −13.18917896 5.7445127 4.8079702 3.9352215 1.0866873 1.2054667 0.6019289 KIAA1737 −0.886856725 0.068365464 0.018501163 −13.18917896 5.3285264 4.8079702 3.9352215 1.0866873 1.2054667 0.6019289 C3orf17 −0.884909513 0.068629673 0.018696943 −13.18917896 5.2636993 4.8079702 3.9352215 1.0866873 1.2054667 0.6019289 CCM2 −0.88241271 0.069332647 0.019002648 −13.18917896 5.3044627 4.8079702 3.9083598 1.0866873 1.2054667 0.6019289 SLC45A1 −0.876539684 0.070539978 0.01974003 −13.18917896 5.8565586 4.8079702 3.7641245 1.0866873 1.2054667 0.6019289 LOC646329 −0.859628068 0.074257601 0.021355211 −13.18917896 3.8399484 4.8079702 4.9444683 1.0866873 1.2054667 0.6019289 MFSD9 −0.827594489 0.08341132 0.026116505 −13.18917896 6.186289 4.8079702 3.3243747 1.0866873 1.2054667 0.6019289 LOC100507034 −0.789210257 0.096254372 0.033125251 −13.18917896 4.963444 4.8079702 3.3243747 1.0866873 1.2054667 0.6019289 DNAJC6 −0.761086301 0.107598348 0.039667817 −13.18917896 5.3354128 4.8079702 2.9956812 1.0866873 1.2054667 0.6019289 MCART1 −0.76036557 0.107936957 0.039845944 −13.18917896 5.3162271 4.8079702 2.9956812 1.0866873 1.2054667 0.6019289 DUSP4 −0.802811444 0.091192569 0.030362674 −13.19865944 10.4034739 13.1588246 11.7634226 9.4365051 9.0441909 0.6019289 HMOX2 −0.9074809 0.065205844 0.016561823 −13.25790347 11.7507415 11.7826607 10.8252763 7.0964955 8.1355133 7.7187266 SLC24A2 −0.979159915 0.056444275 0.011816577 −13.26099116 4.815804 4.9115166 4.7549172 1.0866873 1.2054667 0.6019289 SHROOM2 −0.93973829 0.060175708 0.014023911 −13.26099116 4.815804 5.4876732 4.2859964 1.0866873 1.2054667 0.6019289 NEURL3 −0.906087156 0.065387484 0.016680575 −13.26099116 4.815804 6.5023977 3.9083598 1.0866873 1.2054667 0.6019289 ANO2 −0.885674921 0.068524346 0.018631148 −13.26099116 4.815804 3.8720139 5.5929159 1.0866873 1.2054667 0.6019289 PQLC2 −0.88274984 0.069240191 0.018954505 −13.26099116 4.815804 5.297868 3.9083598 1.0866873 1.2054667 0.6019289 TP63 −0.877819293 0.070271956 0.019603627 −13.26099116 4.815804 5.1480825 3.9083598 1.0866873 1.2054667 0.6019289 TTBK2 −0.816821327 0.086878366 0.02794592 −13.26099116 4.815804 3.360637 5.5715986 1.0866873 1.2054667 0.6019289 C15orf39 −0.803013528 0.09115906 0.030306507 −13.26099116 4.815804 5.297868 3.3243747 1.0866873 1.2054667 0.6019289 CCDC85C −0.986505402 0.056015811 0.011435449 −13.35216307 4.815804 4.8079702 4.9444683 1.0866873 1.2054667 0.6019289 ZNF740 −0.94772421 0.059309685 0.013467865 −13.39672335 5.8972917 4.8304956 4.2859964 1.0866873 1.2054667 0.6019289 UCN2 −0.932809134 0.06110322 0.014531814 −13.39672335 4.2098819 4.8304956 5.5969865 1.0866873 1.2054667 0.6019289 TAF5L −0.923553707 0.062190894 0.015179331 −13.39672335 4.2098819 4.8304956 5.2176156 1.0866873 1.2054667 0.6019289 ZNF785 −0.897280299 0.066820774 0.017409131 −13.39672335 5.8565586 4.8304956 3.9083598 1.0866873 1.2054667 0.6019289 PRAF2 −0.893201673 0.067248681 0.017786247 −13.39672335 5.6586086 4.8304956 3.9083598 1.0866873 1.2054667 0.6019289 FLNC −0.827529887 0.08341132 0.026124529 −13.39672335 3.3509967 4.8304956 5.9741452 1.0866873 1.2054667 0.6019289 GTF3C4 −0.804546629 0.090667629 0.030008826 −13.39672335 5.3162271 4.8304956 3.3243747 1.0866873 1.2054667 0.6019289 PNPLA7 −0.801698683 0.091676899 0.030599374 −13.39672335 2.993831 4.8304956 6.7371315 1.0866873 1.2054667 0.6019289 HDX −0.794466501 0.094648791 0.032183262 −13.39672335 5.0569476 4.8304956 3.3243747 1.0866873 1.2054667 0.6019289 SH3GL3 −0.786747415 0.097501748 0.033763139 −13.39672335 3.0245043 4.8304956 5.9741452 1.0866873 1.2054667 0.6019289 SLC2A1 −0.807932462 0.089586442 0.029415069 −13.42007831 9.4704275 9.5338162 8.3873354 5.7241063 7.0925914 0.6019289 CCDC17 −0.938985547 0.060319904 0.014079275 −13.44862092 4.6394091 4.3513152 6.0316576 1.0866873 1.2054667 0.6019289 LCORL −0.931215669 0.061288269 0.014646554 −13.52894396 4.963444 4.3899364 4.7244061 1.0866873 1.2054667 0.6019289 SDR39U1 −0.967280061 0.057324142 0.012467303 −13.62670378 12.0321894 11.7482626 12.2481644 8.2638247 8.2799211 8.1534715 PUS7L −0.95072848 0.058798663 0.013211105 −13.81350423 4.7435639 4.3899364 5.7236017 1.0866873 1.2054667 0.6019289 SMYD5 −0.949556833 0.05905879 0.01328733 −13.81350423 5.7794294 4.3899364 4.7244061 1.0866873 1.2054667 0.6019289 LOC399715 −0.948531938 0.059271835 0.013413303 −13.81350423 4.7435639 4.3899364 5.5715986 1.0866873 1.2054667 0.6019289 ZCCHC6 −0.93864086 0.060337931 0.014103346 −13.81350423 4.6394091 4.3899364 5.5969865 1.0866873 1.2054667 0.6019289 ANKRD49 −0.924168861 0.06209712 0.015136003 −13.81350423 6.0999914 4.3899364 4.4498938 1.0866873 1.2054667 0.6019289 C15orf40 −0.769196988 0.104415043 0.037738105 −13.81350423 5.7445127 4.3899364 5.5446534 1.6938929 2.9023413 0.6019289 IFI44L −0.755362469 0.110198518 0.041116104 −13.81350423 5.3162271 4.3899364 5.6099449 3.1012538 1.2054667 0.6019289 MPHOSPH6 −0.730394597 0.122181851 0.048080719 −13.85391663 9.1327388 9.8744841 8.4281467 5.3405168 8.2799211 0.6019289 SDF4 −0.910345458 0.064737869 0.016328332 −13.85918352 12.606325 12.2421592 11.5684125 9.3947409 1.2054667 8.4493889 HNRNPU −0.928092542 0.061611794 0.014865602 −13.96666639 12.9759544 13.4373245 13.701247 9.6334087 8.618585 10.0722095 RIPK1 −0.888433847 0.068142722 0.018346305 −14.01491523 10.3056141 9.5640624 9.1184541 6.4903918 1.2054667 6.496723 HOXC5 −0.957917723 0.058190948 0.012890957 −14.03924755 4.815804 4.4133226 5.5446534 1.0866873 1.2054667 0.6019289 SNX18 −0.956511083 0.058267533 0.012936693 −14.03924755 6.186289 4.4133226 4.7244061 1.0866873 1.2054667 0.6019289 FIG4 −0.947519062 0.059309685 0.013483912 −14.03924755 5.3044627 4.4133226 4.7549172 1.0866873 1.2054667 0.6019289 HIST2H2BF −0.938921486 0.060319904 0.014087298 −14.03924755 4.6820765 4.4133226 5.2252164 1.0866873 1.2054667 0.6019289 PPFIA4 −0.917217777 0.063325847 0.01569606 −14.03924755 5.3354128 4.4133226 4.4498938 1.0866873 1.2054667 0.6019289 BSCL2 −0.75731644 0.109468311 0.040627457 −14.05710257 3.0245043 4.9115166 5.018694 1.0866873 1.2054667 0.6019289 TIMM8A −0.995568387 0.055453935 0.011107278 −14.17060296 4.815804 4.9115166 4.9444683 1.0866873 1.2054667 0.6019289 LOC285074 −0.953083847 0.058645827 0.013126855 −14.17060296 4.309025 4.9115166 5.5969865 1.0866873 1.2054667 0.6019289 PREX2 −0.946675917 0.059349536 0.013548102 −14.17060296 4.2098819 4.9115166 6.0316576 1.0866873 1.2054667 0.6019289 RNF121 −0.890044132 0.067956016 0.01818583 −14.17060296 5.3285264 4.9115166 3.9083598 1.0866873 1.2054667 0.6019289 C14orf176 −0.846874852 0.077605332 0.02300329 −14.17060296 3.3509967 4.9115166 6.6010094 1.0866873 1.2054667 0.6019289 ITGAL −0.840347968 0.079182309 0.023978978 −14.17060296 3.3509967 4.9115166 6.2829045 1.0866873 1.2054667 0.6019289 PKI55 −0.886016594 0.068486123 0.018581401 −14.1822691 6.4532097 6.0604012 4.2859964 2.6271932 1.2054667 0.6019289 PPIF −0.979337463 0.05641197 0.011792506 −14.32277854 11.6432418 12.0448681 11.7554265 8.2046286 8.1688761 0.6019289 AKR1C2 −0.986909742 0.056015811 0.011411378 −14.39968022 7.8277675 4.9115166 4.4498938 1.0866873 1.2054667 0.6019289 ITGA2 −0.972015183 0.056976583 0.012126294 −14.39968022 4.7435639 8.2468542 4.4498938 1.0866873 1.2054667 0.6019289 GJC3 −0.969905803 0.057171148 0.012279547 −14.39968022 4.7435639 7.5649923 4.4498938 1.0866873 1.2054667 0.6019289 LOC100292680 −0.96071379 0.057915811 0.012753751 −14.39968022 4.815804 5.4346801 4.4498938 1.0866873 1.2054667 0.6019289 E2F2 −0.952472929 0.058717048 0.013171788 −14.39968022 5.3285264 4.7507076 4.4498938 1.0866873 1.2054667 0.6019289 HOOK1 −0.952066377 0.058745484 0.013187836 −14.39968022 4.6394091 6.1842483 4.4498938 1.0866873 1.2054667 0.6019289 PPME1 −0.949361138 0.059079344 0.013303378 −14.39968022 5.0569476 4.8079702 4.4498938 1.0866873 1.2054667 0.6019289 KIDINS220 −0.942843974 0.059848162 0.013801653 −14.39968022 4.6820765 5.1957839 4.4498938 1.0866873 1.2054667 0.6019289 FDPSL2A −0.928367818 0.061590622 0.014842333 −14.39968022 5.3044627 5.4346801 4.4498938 1.6938929 1.2054667 0.6019289 GOLGA5 −0.732634546 0.121002258 0.04733772 −14.39968022 7.2186326 5.297868 4.4498938 3.9905627 1.2054667 0.6019289 NASP −0.975778307 0.056551597 0.011932119 −14.41456301 11.7533953 11.7743687 12.3937135 8.180253 8.5442583 0.6019289 PCDHB19P −0.976195217 0.056551597 0.011908048 −14.43481723 5.0569476 4.7365865 4.7244061 1.0866873 1.2054667 0.6019289 CCNB1IP1 −0.958825268 0.058132446 0.012858862 −14.43481723 5.0569476 4.8304956 4.5083337 1.0866873 1.2054667 0.6019289 MAST2 −0.94025906 0.060114874 0.01399984 −14.4908788 11.0339514 11.1277725 12.3558728 8.4987997 7.6601162 0.6019289 NETO2 −0.959824261 0.057974898 0.012785846 −14.49798945 4.2634629 6.3119075 4.9444683 1.0866873 1.2054667 0.6019289 OIP5-AS1 −0.954421279 0.058488069 0.013062665 −14.49798945 5.3044627 4.3513152 4.9444683 1.0866873 1.2054667 0.6019289 KLHDC9 −0.928801674 0.061490252 0.014795796 −14.49798945 4.2098819 5.1480825 4.9444683 1.0866873 1.2054667 0.6019289 POLA1 −0.894940416 0.067128739 0.017632994 −14.49798945 6.2275774 3.7709946 4.9444683 1.0866873 1.2054667 0.6019289 FAM169B −0.886995155 0.068365464 0.018462649 −14.49798945 5.3285264 3.8720139 4.9444683 1.0866873 1.2054667 0.6019289 DMBX1 −0.813967286 0.087666999 0.028409693 −14.49798945 5.2636993 3.360637 4.9444683 1.0866873 1.2054667 0.6019289 LYSMD3 −0.763882262 0.106557388 0.03900345 −14.49798945 5.8565586 2.8096013 4.9444683 1.0866873 1.2054667 0.6019289 MDK −0.805066433 0.090425668 0.029869213 −14.52989826 10.1665236 11.3436619 11.7403133 7.4827092 1.2054667 9.4058315 FMNL3 −0.862499446 0.073380796 0.02096606 −14.60735401 10.4169274 9.1280672 11.0657244 7.1971015 1.2054667 7.141714 PPP1R16A −0.995699659 0.055419354 0.01109123 −14.68994094 4.963444 4.7365865 5.018694 1.0866873 1.2054667 0.6019289 CCDC136 −0.970852506 0.057122382 0.012213753 −14.68994094 4.963444 4.3899364 5.7236017 1.0866873 1.2054667 0.6019289 C3orf74 −0.950228548 0.058798663 0.013219129 −14.68994094 4.963444 5.4346801 4.2859964 1.0866873 1.2054667 0.6019289 C2CD4A −0.92224424 0.062363889 0.015252347 −14.68994094 4.963444 6.8213295 3.9083598 1.0866873 1.2054667 0.6019289 PCDHB15 −0.8994577 0.066432398 0.017179652 −14.68994094 4.963444 3.8720139 5.7236017 1.0866873 1.2054667 0.6019289 CHI3L2 −0.861580236 0.073534549 0.021046297 −14.68994094 4.963444 7.440099 3.3243747 1.0866873 1.2054667 0.6019289 VIPR2 −0.724139645 0.12474266 0.049930193 −14.68994094 4.963444 2.406905 6.0721689 1.0866873 1.2054667 0.6019289 SLC3A2 −0.849534926 0.07698033 0.022704004 −14.69215517 12.31447 11.8682633 11.9334135 9.44676 7.5630806 8.0564393 URGCP −0.728833633 0.12296007 0.048508385 −14.73532721 8.062715 7.8717699 7.8250252 3.9905627 6.9463683 0.6019289 EIF3J −0.936587926 0.060682102 0.014235738 −14.9390924 10.9251791 12.2260351 11.9182731 1.0866873 8.3250145 8.2662493 TMBIM1 −0.925542759 0.06185043 0.015045334 −14.94364839 13.3369313 12.6657897 12.4255567 8.3206874 9.4354708 9.0627933 KLF15 −0.971136783 0.057101475 0.012190484 −14.99494982 6.4876101 4.7365865 4.5083337 1.0866873 1.2054667 0.6019289 RBM43 −0.968228825 0.057313185 0.012427184 −14.99494982 6.0548278 4.7365865 4.5083337 1.0866873 1.2054667 0.6019289 TSPAN17 −0.965319394 0.057395438 0.012547541 −14.99494982 5.7530242 4.7365865 4.5083337 1.0866873 1.2054667 0.6019289 PPP1R3A −0.969801358 0.057171148 0.012295595 −15.12876689 11.6026113 10.3241015 10.8759415 6.9599943 7.6833888 0.6019289 QRSL1 −0.932186978 0.06110322 0.014563909 −15.12924244 10.1124251 10.5759834 10.175278 7.5025051 1.2054667 6.2560101 CALU −0.773206571 0.102731018 0.036791302 −15.1826568 12.9262534 11.5215357 11.9907327 11.5237292 8.0663803 0.6019289 ATM −0.981437281 0.056391645 0.011752387 −15.2634239 5.8972917 4.4133226 5.018694 1.0866873 1.2054667 0.6019289 TRIML2 −0.888091599 0.068142722 0.018370376 −15.2634239 3.8399484 5.3621423 5.018694 1.0866873 1.2054667 0.6019289 RELL2 −0.839223046 0.079358501 0.02414186 −15.2634239 5.8972917 3.360637 5.018694 1.0866873 1.2054667 0.6019289 DDX10 −1.016733339 0.053584658 0.01009789 −15.37607941 4.815804 5.1480825 5.018694 1.0866873 1.2054667 0.6019289 C11orf46 −0.846654646 0.077638018 0.023025756 −15.40021146 6.0082059 6.5720715 3.9352215 2.6271932 1.2054667 0.6019289 PRRC2B −0.927119866 0.061709548 0.014952259 −15.57126168 12.419569 12.5726936 12.7057679 9.8991573 1.2054667 8.6118796 HSF1 −0.978029137 0.056452334 0.011840648 −15.59060532 11.4658356 12.2069929 11.0559919 7.5976045 1.2054667 8.2443879 SEC61A1 −0.958224345 0.058154469 0.012873305 −15.63502711 13.9318442 13.0981071 12.4640905 9.5068039 9.1313973 8.6456318 SDS −0.994094449 0.055573321 0.01115863 −15.67355243 5.0569476 4.3899364 7.9423658 1.0866873 1.2054667 0.6019289 CROT −0.984491465 0.056097909 0.011544572 −15.67355243 5.0569476 5.297868 4.5083337 1.0866873 1.2054667 0.6019289 NUP107 −0.981882031 0.056371224 0.01173634 −15.67355243 5.0569476 5.4876732 4.4498938 1.0866873 1.2054667 0.6019289 PPP1R14C −0.91253866 0.064224388 0.01605071 −15.67355243 5.0569476 5.7897017 3.9083598 1.0866873 1.2054667 0.6019289 ADPRHL1 −0.889348037 0.068037763 0.018258846 −15.67355243 5.0569476 3.8720139 5.2176156 1.0866873 1.2054667 0.6019289 ENTPD2 −0.727588729 0.123357599 0.048961727 −15.67355243 5.0569476 6.9047187 2.1654208 1.0866873 1.2054667 0.6019289 CKB −0.912486407 0.064224388 0.016066758 −15.77538473 11.9050961 13.1837362 13.5890269 7.9254928 9.9051779 8.4301508 NXF1 −0.921624763 0.062559106 0.01533098 −15.84700527 13.1879532 14.2868575 14.4898903 10.3007191 9.5347853 10.3984929 AKNA −0.991626336 0.055698998 0.01122282 −15.92484719 12.2860376 12.6880319 13.4351605 8.6215576 8.8926726 8.6948242 PHB2 −1.012380119 0.054044749 0.010282436 −15.93908648 14.4464319 14.7785443 14.188872 10.6258278 10.3635077 10.4519348 RPS6 −0.934828642 0.060960411 0.014383375 −15.98285773 17.3519419 18.2820626 17.6491629 12.6330859 14.2836091 14.160494 IL12B −1.012968249 0.054044749 0.010242317 −16.1353043 5.0569476 4.7365865 5.2176156 1.0866873 1.2054667 0.6019289 PLCD4 −1.002392438 0.054766682 0.010790339 −16.22053786 4.815804 4.8304956 5.2252164 1.0866873 1.2054667 0.6019289 CAPN10 −0.981011671 0.056391645 0.011760411 −16.421115 4.6394091 4.7365865 5.7236017 1.0866873 1.2054667 0.6019289 MURC −0.869863337 0.071778384 0.02035465 −16.421115 4.6394091 5.4346801 6.0560619 2.6271932 1.2054667 0.6019289 CAPZB −1.042678019 0.052218844 0.009249779 −16.51979571 14.5045577 13.7708539 13.6218332 9.72473 9.9101189 9.62472 RPUSD3 −0.819614943 0.085991355 0.027484554 −16.65903114 5.2636993 5.1480825 3.3243747 1.0866873 1.2054667 0.6019289 NHLRC1 −1.030233833 0.05293768 0.009654979 −16.69558977 4.815804 5.1480825 5.2252164 1.0866873 1.2054667 0.6019289 ROGDI −1.004920568 0.054532631 0.010664367 −16.69558977 5.8565586 5.1480825 4.5083337 1.0866873 1.2054667 0.6019289 BMP6 −0.983055676 0.056243388 0.011626414 −16.69558977 4.309025 5.1480825 6.2829045 1.0866873 1.2054667 0.6019289 NLRX1 −0.982168494 0.056371224 0.011720292 −16.69558977 6.4876101 5.1480825 4.2859964 1.0866873 1.2054667 0.6019289 SPCS2 −0.982070357 0.056371224 0.011728316 −16.69558977 5.3044627 5.1480825 4.4498938 1.0866873 1.2054667 0.6019289 C9orf152 −0.975870736 0.056551597 0.011924095 −16.69558977 4.2098819 5.1480825 6.8910052 1.0866873 1.2054667 0.6019289 MCM9 −0.932445242 0.06110322 0.014555885 −16.69558977 6.2677178 5.1480825 3.9352215 1.0866873 1.2054667 0.6019289 SCT −0.840503323 0.079141153 0.023940464 −16.69558977 3.3509967 5.1480825 5.7236017 1.0866873 1.2054667 0.6019289 LOC442459 −0.798793615 0.093160485 0.031355211 −16.69558977 5.8565586 5.1480825 2.9956812 1.0866873 1.2054667 0.6019289 RNH1 −0.948124939 0.059309685 0.01343577 −16.69619213 13.619617 12.8615819 12.27568 8.8001347 1.2054667 10.1029082 SRRT −0.99083686 0.055727384 0.011254915 −16.70246805 12.0681612 12.5306452 12.261635 6.0269554 8.8826529 8.1996456 RHEBL1 −1.010885495 0.054161962 0.010378721 −16.91401854 4.6820765 4.9115166 6.7371315 1.0866873 1.2054667 0.6019289 GCNT1 −1.002311307 0.054766682 0.010798363 −16.91401854 4.6820765 4.9115166 5.5446534 1.0866873 1.2054667 0.6019289 C1orf220 −0.986090906 0.056015811 0.01145952 −16.91401854 4.6820765 4.7365865 5.7236017 1.0866873 1.2054667 0.6019289 HLA-L −0.985782589 0.056084432 0.011482789 −16.91401854 4.6820765 4.7507076 5.5715986 1.0866873 1.2054667 0.6019289 SYN2 −0.984009846 0.056097909 0.011568643 −16.91401854 4.6820765 5.6616851 4.7244061 1.0866873 1.2054667 0.6019289 GPR110 −0.982707654 0.056301234 0.011648881 −16.91401854 4.6820765 4.7507076 5.3892653 1.0866873 1.2054667 0.6019289 DLST −0.927886582 0.061636261 0.01488165 −16.91401854 4.6820765 6.0497213 6.3558005 2.6271932 1.2054667 0.6019289 UBQLN4 −0.872161462 0.071512479 0.020138009 −17.05829267 5.3162271 5.297868 5.2176156 2.6271932 1.2054667 0.6019289 C15orf52 −0.889458921 0.068025256 0.018226751 −17.1364458 5.3044627 5.297868 3.7641245 1.0866873 1.2054667 0.6019289 HN1L −1.02519858 0.05313101 0.009785766 −17.21295244 11.387139 12.0578318 11.6813945 7.2911484 7.4857665 7.9524091 LOC220729 −1.038967719 0.052564289 0.009379764 −17.25684206 4.6820765 5.1957839 6.5278107 1.0866873 1.2054667 0.6019289 HACL1 −1.010725945 0.054161962 0.010386745 −17.25684206 5.982974 5.1957839 4.5083337 1.0866873 1.2054667 0.6019289 ANKMY1 −1.010546879 0.054161962 0.010394769 −17.25684206 6.8989234 5.1957839 4.4498938 1.0866873 1.2054667 0.6019289 SLC13A4 −0.984037104 0.056097909 0.011560619 −17.25684206 4.309025 5.1957839 6.0721689 1.0866873 1.2054667 0.6019289 WFIKKN1 −0.925711587 0.06185043 0.01503731 −17.25684206 3.8399484 5.1957839 6.4105447 1.0866873 1.2054667 0.6019289 EPHB2 −1.064062186 0.051416052 0.008539677 −17.27675605 5.3162271 5.1957839 5.018694 1.0866873 1.2054667 0.6019289 PLEKHG5 −0.739305473 0.1180144 0.045586135 −17.27675605 5.3162271 4.7365865 5.5446534 3.4605153 1.2054667 0.6019289 IER3 −0.901012889 0.066271613 0.017061703 −17.34672646 13.3310215 14.646838 14.3002414 9.21443 11.3371844 9.482544 TSPYL2 −0.954249863 0.058516799 0.013078713 −17.41463728 14.7435364 13.8092403 15.6074533 10.6213079 11.8708107 0.6019289 ZSCAN16 −1.039429149 0.052533354 0.009363717 −17.41763908 6.4179694 5.1480825 4.7244061 1.0866873 1.2054667 0.6019289 HAS3 −1.021979615 0.053385633 0.009896494 −17.41763908 4.963444 8.0533052 4.7244061 1.0866873 1.2054667 0.6019289 RAB15 −0.996570735 0.055419354 0.011067159 −17.41763908 4.7435639 6.4291897 4.7244061 1.0866873 1.2054667 0.6019289 ASL −1.036739808 0.052603935 0.009445559 −17.42467348 5.3285264 5.297868 5.5715986 1.6938929 1.2054667 0.6019289 TET3 −0.99628127 0.055419354 0.011083206 −17.50804512 5.3354128 4.8079702 4.7549172 1.0866873 1.2054667 0.6019289 FGD2 −1.080312244 0.051255379 0.008124047 −17.51996815 5.3162271 5.1480825 5.2176156 1.0866873 1.2054667 0.6019289 DYNC1H1 −1.038734459 0.052564289 0.009387788 −17.51996815 5.2636993 4.8304956 5.2176156 1.0866873 1.2054667 0.6019289 POLR3C −0.994465392 0.055530925 0.011140977 −17.51996815 5.7445127 4.4133226 5.2176156 1.0866873 1.2054667 0.6019289 ICA1 −0.990414455 0.055727384 0.011262938 −17.51996815 4.309025 6.4291897 5.2176156 1.0866873 1.2054667 0.6019289 RBMY2FP −0.984391482 0.056097909 0.011552596 −17.51996815 5.7003762 4.3513152 5.2176156 1.0866873 1.2054667 0.6019289 PPTC7 −1.014488761 0.053847872 0.010166894 −17.56531502 4.963444 4.7365865 5.5446534 1.0866873 1.2054667 0.6019289 PLSCR2 −1.004932597 0.054532631 0.010656343 −17.56531502 4.815804 4.7365865 6.1759311 1.0866873 1.2054667 0.6019289 CTBP2 −1.036808341 0.052603935 0.009437535 −17.57134353 5.3044627 5.3406193 5.5446534 1.6938929 1.2054667 0.6019289 CCNYL1 −1.086573831 0.051099543 0.007956351 −17.61251609 5.3285264 5.1957839 5.2252164 1.0866873 1.2054667 0.6019289 DCLRE1B −0.989225859 0.055849348 0.0113175 −17.61251609 5.8972917 4.3513152 5.2252164 1.0866873 1.2054667 0.6019289 LOC286359 −0.984590815 0.056097909 0.011536548 −17.61251609 5.4911209 4.3899364 5.2252164 1.0866873 1.2054667 0.6019289 MRP63 −0.812526249 0.088296719 0.028700955 −17.61251609 6.9491661 6.6056864 5.2252164 1.0866873 1.2054667 4.3970308 TGM5 −0.726075807 0.124034522 0.049381369 −17.61251609 1.8744435 7.6317881 5.2252164 1.0866873 1.2054667 0.6019289 ITGB8 −1.049407943 0.051974546 0.009034743 −17.65047354 4.7435639 7.8154118 5.2176156 1.0866873 1.2054667 0.6019289 CALCA −1.017152669 0.053550528 0.010082645 −17.65047354 4.7435639 5.8096013 4.9444683 1.0866873 1.2054667 0.6019289 NIPAL1 −0.933866668 0.060990824 0.014454786 −17.65047354 4.7435639 4.7507076 5.9741452 1.6938929 1.2054667 0.6019289 SP140L −0.86832499 0.07203996 0.02045254 −17.65944717 8.8382996 8.3296681 8.2799514 5.8529567 4.1872998 4.0446258 MED10 −1.026604158 0.053094283 0.009736019 −17.73808861 5.8972917 4.7507076 5.018694 1.0866873 1.2054667 0.6019289 DIO3 −1.002914562 0.054659392 0.010750221 −17.73808861 4.815804 4.7507076 5.7029118 1.0866873 1.2054667 0.6019289 PLAC8L1 −1.001561609 0.054889674 0.010849715 −17.73808861 4.815804 4.7507076 5.5969865 1.0866873 1.2054667 0.6019289 LGSN −1.034904764 0.052782082 0.009520982 −17.78992245 5.0569476 6.7924268 4.7549172 1.0866873 1.2054667 0.6019289 CDH3 −1.010269768 0.054185592 0.010426061 −17.78992245 4.815804 7.8717699 4.7549172 1.0866873 1.2054667 0.6019289 HYOU1 −0.843021754 0.078689412 0.023648399 −17.78992245 8.5352855 6.7020747 4.7549172 4.5400907 1.2054667 0.6019289 CCDC41 −1.061808472 0.051493437 0.008627939 −17.83544858 4.963444 5.3621423 5.2252164 1.0866873 1.2054667 0.6019289 NAP1L4 −0.920246948 0.062900898 0.01545615 −18.0696402 12.7223886 13.4518404 13.0908792 8.9153833 1.2054667 10.7090071 LYRM2 −1.071715123 0.051355105 0.008334269 −18.08863901 5.2636993 5.3621423 5.018694 1.0866873 1.2054667 0.6019289 CADPS2 −1.06806104 0.051378258 0.00839525 −18.08863901 5.2636993 5.297868 5.018694 1.0866873 1.2054667 0.6019289 CCDC154 −1.046078406 0.052154186 0.009143866 −18.08863901 5.2636993 4.7507076 5.7029118 1.0866873 1.2054667 0.6019289 TMEM8A −0.905538953 0.065433337 0.016703041 −18.08863901 5.2636993 5.7897017 3.7641245 1.0866873 1.2054667 0.6019289 CHMP4C −0.747487226 0.11383441 0.043184626 −18.08863901 5.2636993 7.1970971 2.1654208 1.0866873 1.2054667 0.6019289 FLJ16341 −1.039807551 0.052533354 0.009355693 −18.17393109 4.7435639 5.3406193 5.3892653 1.0866873 1.2054667 0.6019289 DAGLB −0.980982056 0.056391645 0.011768435 −18.17393109 5.3354128 4.3513152 5.3892653 1.0866873 1.2054667 0.6019289 LEPRE1 −0.980036899 0.05641197 0.011784482 −18.17393109 5.3162271 4.3513152 5.3892653 1.0866873 1.2054667 0.6019289 DDN −0.788527044 0.096601594 0.03332424 −18.17393109 2.993831 5.297868 5.3892653 1.0866873 1.2054667 0.6019289 CXorf65 −0.96484037 0.0574622 0.012587659 −18.39725212 11.7391851 10.9362428 10.2793206 7.268205 7.5377667 0.6019289 PCGF1 −1.058944549 0.051725293 0.008753912 −18.52216349 6.7650859 5.297868 4.7549172 1.0866873 1.2054667 0.6019289 ALG1 −1.053480386 0.051888429 0.008907165 −18.52216349 4.7435639 5.297868 6.0540376 1.0866873 1.2054667 0.6019289 CES3 −0.983299566 0.056243388 0.01161839 −18.52216349 4.2634629 5.297868 5.9741452 1.0866873 1.2054667 0.6019289 SLC33A1 −0.868729768 0.07202519 0.020436492 −18.52216349 6.5540448 5.297868 3.3243747 1.0866873 1.2054667 0.6019289 ITGA11 −0.844617366 0.07808379 0.02333788 −18.52216349 3.0245043 5.297868 7.1323668 1.0866873 1.2054667 0.6019289 LOC100129617 −0.813311595 0.087899593 0.028514001 −18.52216349 2.993831 5.297868 6.0540376 1.0866873 1.2054667 0.6019289 IL24 −0.754050432 0.110813327 0.041473161 −18.52216349 6.5212096 5.297868 2.3793449 1.0866873 1.2054667 0.6019289 PIGZ −1.056819349 0.051814299 0.00882773 −18.55678797 4.815804 6.0361098 5.2252164 1.0866873 1.2054667 0.6019289 MRAP2 −1.050326209 0.051900312 0.008994624 −18.55678797 4.815804 5.3406193 5.3892653 1.0866873 1.2054667 0.6019289 ANKRD16 −1.066376798 0.051378258 0.008451416 −18.60702339 5.3044627 4.8079702 6.6706745 1.0866873 1.2054667 0.6019289 MYLPF −1.011868486 0.054077708 0.010298484 −18.60702339 5.3044627 6.0441977 4.4498938 1.0866873 1.2054667 0.6019289 C11orf61 −1.006403301 0.054519995 0.010600979 −18.60702339 5.3044627 4.4133226 6.0316576 1.0866873 1.2054667 0.6019289 ZNF768 −0.985307509 0.056096089 0.011514082 −18.60702339 5.3044627 4.3513152 5.5446534 1.0866873 1.2054667 0.6019289 CMTM4 −0.915707643 0.063435834 0.015744203 −18.60702339 5.3044627 6.0726357 3.7641245 1.0866873 1.2054667 0.6019289 MSR1 −0.882838258 0.069229646 0.018936853 −18.60702339 5.3044627 3.360637 7.0032858 1.0866873 1.2054667 0.6019289 LOC401321 −1.051746214 0.051900312 0.008962529 −18.74672502 5.3285264 4.8304956 5.3892653 1.0866873 1.2054667 0.6019289 LRRC8B −1.036843982 0.052603935 0.009429511 −18.74672502 5.0569476 4.8304956 5.5969865 1.0866873 1.2054667 0.6019289 LOC100289495 −1.032005546 0.052917554 0.009616465 −18.74672502 4.963444 4.8304956 6.0560619 1.0866873 1.2054667 0.6019289 PAK6 −1.00394672 0.054558959 0.010704485 −18.75937447 5.3162271 7.6317881 4.2859964 1.0866873 1.2054667 0.6019289 CTF1 −0.779568344 0.100080374 0.035291663 −18.75937447 5.3162271 2.8096013 5.7236017 1.0866873 1.2054667 0.6019289 BCL2L11 −0.972877471 0.056901344 0.01205408 −18.80321009 11.6336712 11.2484254 12.1915069 8.6661239 2.5373444 7.4007641 LOC100129550 −1.080030009 0.051255379 0.008132071 −18.91998555 5.3285264 5.4346801 5.018694 1.0866873 1.2054667 0.6019289 ANKS1A −1.065282036 0.051378258 0.008499559 −18.91998555 5.3285264 4.8079702 6.0540376 1.0866873 1.2054667 0.6019289 DAPP1 −1.031537473 0.052917554 0.009624488 −18.91998555 5.3285264 7.4023354 4.5083337 1.0866873 1.2054667 0.6019289 MICALL2 −1.013861957 0.053847872 0.010182942 −18.91998555 5.3285264 5.6616851 4.5083337 1.0866873 1.2054667 0.6019289 SP9 −1.005756306 0.054519995 0.010617026 −18.91998555 5.3285264 4.3513152 6.4897707 1.0866873 1.2054667 0.6019289 USF1 −1.004791737 0.054532631 0.01067239 −18.91998555 5.3285264 4.3899364 6.0316576 1.0866873 1.2054667 0.6019289 EPC1 −0.84068558 0.079132386 0.02389874 −18.91998555 5.3285264 3.3213504 5.5715986 1.0866873 1.2054667 0.6019289 POU2F3 −0.732063433 0.121322681 0.047503009 −18.91998555 5.3285264 6.537655 2.1654208 1.0866873 1.2054667 0.6019289 BEND3 −1.067853566 0.051378258 0.008411297 −19.0105118 5.3354128 4.8079702 6.2829045 1.0866873 1.2054667 0.6019289 SELP −1.058480372 0.051725293 0.008777983 −19.0105118 5.3354128 6.7629335 4.7244061 1.0866873 1.2054667 0.6019289 LAYN −1.058089052 0.051725293 0.00879403 −19.0105118 5.3354128 6.0361098 4.7549172 1.0866873 1.2054667 0.6019289 MYCT1 −1.056160909 0.051814299 0.008843778 −19.0105118 5.3354128 4.8079702 5.5715986 1.0866873 1.2054667 0.6019289 TNFSF10 −1.059661739 0.051660967 0.008706571 −19.07924221 4.7435639 5.3406193 6.3267171 1.0866873 1.2054667 0.6019289 TSSC1 −0.92167222 0.062529069 0.015313327 −19.07924221 6.2275774 5.3406193 3.7641245 1.0866873 1.2054667 0.6019289 MAZ −0.926606407 0.061733832 0.01497633 −19.24211565 12.2140107 11.3235963 12.539366 8.9590228 7.0574008 7.7807893 ABCC10 −0.989171293 0.055849348 0.011325524 −19.36601165 5.8972917 5.3621423 4.2859964 1.0866873 1.2054667 0.6019289 NOP14 −1.048865362 0.051974546 0.009058814 −19.456853 5.0569476 5.4876732 4.9444683 1.0866873 1.2054667 0.6019289 ARHGAP39 −1.109443785 0.050523319 0.007292787 −19.50340646 5.4911209 5.3406193 5.2252164 1.0866873 1.2054667 0.6019289 E4F1 −1.033043144 0.052897282 0.009593998 −19.50340646 5.4911209 4.9115166 4.9444683 1.0866873 1.2054667 0.6019289 GEMIN8 −0.845637154 0.077914269 0.023184626 −19.50340646 5.4911209 3.360637 5.3892653 1.0866873 1.2054667 0.6019289 INTS10 −0.788588211 0.096601594 0.033316216 −19.56952071 9.9053047 9.4437316 8.9109561 5.1531951 8.2951094 0.6019289 RTKN −1.058692464 0.051725293 0.008769959 −19.73354129 4.6820765 7.5477987 5.3892653 1.0866873 1.2054667 0.6019289 LOC100126784 −1.052153113 0.051900312 0.008946482 −19.73354129 4.6394091 6.7924268 5.3892653 1.0866873 1.2054667 0.6019289 AGT −1.001601344 0.054889674 0.010841691 −19.73354129 4.309025 6.270596 5.3892653 1.0866873 1.2054667 0.6019289 RAVER2 −1.000919056 0.054963463 0.010891439 −19.73354129 4.309025 6.2280676 5.3892653 1.0866873 1.2054667 0.6019289 EDN2 −0.889144176 0.068037763 0.018274894 −19.73354129 3.3509967 7.1060646 5.3892653 1.0866873 1.2054667 0.6019289 CNIH4 −1.085839165 0.051099543 0.007964375 −19.82965461 6.0999914 4.9115166 5.3892653 1.0866873 1.2054667 0.6019289 PARP9 −1.065601862 0.051378258 0.008483511 −19.82965461 5.7445127 4.9115166 5.2176156 1.0866873 1.2054667 0.6019289 SLC7A11 −0.983498366 0.056177581 0.011594319 −20.04859947 6.8468682 7.2617905 4.9444683 1.0866873 1.2054667 2.9363609 LETM2 −1.120873605 0.050341156 0.006964615 −20.24069278 5.3044627 5.3406193 5.5446534 1.0866873 1.2054667 0.6019289 LOC100507501 −1.090800347 0.050995256 0.007780631 −20.24069278 5.0569476 5.3406193 5.5446534 1.0866873 1.2054667 0.6019289 CLDN1 −0.771626601 0.10322713 0.037121881 −20.24069278 5.3285264 6.537655 5.5446534 4.1976103 1.2054667 0.6019289 RNASEH2C −1.090060905 0.051027823 0.007819947 −20.2877834 6.6783891 5.3621423 4.9444683 1.0866873 1.2054667 0.6019289 SCN8A −1.087257029 0.051099543 0.00793228 −20.2877834 6.3067721 5.3406193 4.9444683 1.0866873 1.2054667 0.6019289 TOPBP1 −1.082039442 0.051255379 0.008067881 −20.2877834 5.4911209 5.4876732 4.9444683 1.0866873 1.2054667 0.6019289 INF2 −0.745173385 0.115164025 0.043821712 −20.2877834 6.7078705 7.0338116 4.9444683 5.0495858 1.2054667 0.6019289 ZNF384 −0.920584832 0.062815622 0.015424858 −20.35650695 11.1566394 11.2364018 11.1087264 6.8092213 8.8624022 0.6019289 LOC284950 −1.074705028 0.051291304 0.008229961 −20.36461672 4.815804 5.4346801 6.0125266 1.0866873 1.2054667 0.6019289 RNPC3 −1.054180159 0.051852306 0.008883896 −20.36461672 5.7003762 5.4346801 4.7244061 1.0866873 1.2054667 0.6019289 PYGM −1.04785195 0.052136699 0.009097328 −20.36461672 4.6820765 5.4346801 5.7029118 1.0866873 1.2054667 0.6019289 WAS −1.015335487 0.05365276 0.010119554 −20.36461672 4.309025 5.4346801 7.3390847 1.0866873 1.2054667 0.6019289 WRAP73 −1.007119811 0.054507998 0.010576908 −20.36461672 6.6783891 5.4346801 4.2859964 1.0866873 1.2054667 0.6019289 CHPF2 −0.836740211 0.080425127 0.024620075 −20.36461672 6.5861495 5.4346801 2.9956812 1.0866873 1.2054667 0.6019289 ASZ1 −1.059823672 0.051660967 0.008690524 −20.62227961 5.982974 5.1480825 5.5715986 1.6938929 1.2054667 0.6019289 TRIM68 −0.910649926 0.064737869 0.016288213 −20.62227961 5.4911209 3.7709946 5.5715986 1.0866873 1.2054667 0.6019289 PATL1 −1.0218647 0.053385633 0.009904517 −20.70300639 11.1159753 9.9319425 11.267554 6.7442069 6.9463683 0.6019289 PRKDC −0.956038323 0.058365313 0.01296959 −20.88490167 11.9161912 11.5776788 10.834794 8.6215576 7.1932904 0.6019289 WIPF3 −1.118533324 0.050341156 0.007028805 −20.92925666 5.2636993 5.3406193 5.5929159 1.0866873 1.2054667 0.6019289 NELF −0.933909534 0.060990824 0.014446762 −20.93802018 11.2954278 11.5423038 10.8176167 4.9379926 6.9073747 8.4106527 PLIN2 −0.839739876 0.079317736 0.024088101 −21.03041133 13.0985972 10.6959553 11.8801716 10.5278012 7.4857665 0.6019289 SMPD3 −1.007494581 0.054397005 0.010538394 −21.12655816 4.2098819 5.4876732 7.4222392 1.0866873 1.2054667 0.6019289 SPTBN5 −0.810466905 0.088930093 0.029053197 −21.12655816 2.993831 5.4876732 5.7029118 1.0866873 1.2054667 0.6019289 LOC389641 −1.009603326 0.054296381 0.010474204 −21.17710664 5.4911209 6.537655 4.2859964 1.0866873 1.2054667 0.6019289 LOC100289230 −0.927185635 0.061709548 0.014944235 −21.17710664 5.4911209 3.7709946 6.0540376 1.0866873 1.2054667 0.6019289 ZNF513 −1.126405547 0.050294669 0.006853888 −21.17776189 5.3285264 5.3406193 5.6099449 1.0866873 1.2054667 0.6019289 GPC1 −0.850274044 0.076767438 0.022628581 −21.2441842 9.0941798 10.0465526 7.2279137 4.6851838 6.5504789 0.6019289 USP2 −1.112343074 0.050440463 0.00722298 −21.35889525 6.7928648 5.4876732 5.018694 1.0866873 1.2054667 0.6019289 SH3RF2 −1.097066153 0.050892627 0.007622563 −21.35889525 5.3354128 6.6385363 5.018694 1.0866873 1.2054667 0.6019289 NEDD4 −1.089534581 0.051027823 0.007844018 −21.35889525 5.8565586 5.297868 5.018694 1.0866873 1.2054667 0.6019289 C10orf111 −1.08815903 0.051099543 0.007884137 −21.35889525 5.2636993 6.0497213 5.018694 1.0866873 1.2054667 0.6019289 ESRP2 −1.088103421 0.051099543 0.007892161 −21.35889525 5.3162271 8.464054 5.018694 1.0866873 1.2054667 0.6019289 AGFG2 −1.07206747 0.051291304 0.008298163 −21.35889525 5.7003762 5.1480825 5.018694 1.0866873 1.2054667 0.6019289 NRIP3 −1.07206747 0.051291304 0.008298163 −21.35889525 5.7003762 5.1480825 5.018694 1.0866873 1.2054667 0.6019289 ZNF34 −0.83719034 0.080303025 0.024543047 −21.35889525 6.5540448 6.0924064 5.018694 3.7493131 1.2054667 0.6019289 PSMC2 −0.741828316 0.117105527 0.044811041 −21.35889525 6.186289 6.0726357 5.018694 4.3788962 1.2054667 0.6019289 TMEM68 −0.732064959 0.121322681 0.047494985 −21.35889525 5.7445127 6.7328249 5.018694 4.5400907 1.2054667 0.6019289 DNM1L −0.945244166 0.059597087 0.013657225 −21.52985331 10.1206704 9.9018086 9.6667798 7.2911484 5.473542 0.6019289 UPF3A −1.094464181 0.050952718 0.007685148 −21.90429601 5.6586086 5.1480825 5.2176156 1.0866873 1.2054667 0.6019289 CCDC146 −1.010294501 0.054185592 0.010418037 −21.90429601 5.6586086 4.3899364 5.5969865 1.0866873 1.2054667 0.6019289 TAP2 −1.10726228 0.050608213 0.007365803 −21.93280923 5.0569476 6.270596 5.3892653 1.0866873 1.2054667 0.6019289 IRF8 −1.098614716 0.050846008 0.007582444 −21.93280923 5.0569476 5.3406193 7.7138893 1.0866873 1.2054667 0.6019289 LAMC2 −0.858147586 0.07443975 0.021514082 −21.93280923 5.0569476 8.3396934 6.976024 1.0866873 4.8088443 0.6019289 ALDOA −1.043740778 0.052218844 0.009217684 −21.96444367 14.6760218 14.5515264 13.9105947 10.0944284 9.1731002 10.6056134 SLC16A7 −1.078675722 0.051291304 0.008165771 −21.97766377 5.7530242 4.8304956 5.5446534 1.0866873 1.2054667 0.6019289 LOC389906 −1.023854055 0.053244867 0.009832304 −21.97766377 4.309025 7.282726 5.5446534 1.0866873 1.2054667 0.6019289 SLC29A1 −0.956998844 0.058245659 0.01292225 −22.09386148 11.4539207 11.8036371 10.8573834 6.988347 1.2054667 8.6288544 ALG13 −0.994850358 0.055488459 0.011123325 −22.29844786 6.0548278 7.1060646 5.018694 2.6271932 1.2054667 0.6019289 LOC442421 −1.104466196 0.050647945 0.007486159 −22.39199677 6.4532097 4.9115166 5.5715986 1.0866873 1.2054667 0.6019289 ZWILCH −1.081430513 0.051255379 0.008083928 −22.39199677 6.4876101 4.7507076 5.5715986 1.0866873 1.2054667 0.6019289 DHODH −1.009753746 0.054264218 0.010458156 −22.39199677 4.309025 6.0726357 5.5715986 1.0866873 1.2054667 0.6019289 LOC148413 −0.902946945 0.06582776 0.016879564 −22.39199677 7.1558353 3.360637 5.5715986 1.0866873 1.2054667 0.6019289 TMEM45B −0.947082387 0.059314973 0.013522426 −22.54771722 5.7003762 5.6616851 3.9352215 1.0866873 1.2054667 0.6019289 TMEM120B −1.010431802 0.054161962 0.010402792 −22.58738183 6.4179694 5.6616851 5.7029118 2.6271932 1.2054667 0.6019289 ZNF385A −0.878330612 0.070167691 0.019493701 −22.68564918 10.7341965 10.1326825 11.2290953 6.2304884 1.2054667 8.818351 ITPR2 −1.093345617 0.050952718 0.007741314 −22.7253173 6.8989234 4.8079702 5.5929159 1.0866873 1.2054667 0.6019289 SNORD100 −1.074874013 0.051291304 0.008221937 −22.7253173 4.6820765 6.7020747 5.5929159 1.0866873 1.2054667 0.6019289 UTS2D −1.024967758 0.05313101 0.00979379 −22.7253173 6.0082059 4.4133226 5.5929159 1.0866873 1.2054667 0.6019289 PIK3R3 −1.008582845 0.054397005 0.010522346 −22.73029278 7.6263253 7.2405467 8.6938442 3.7493131 4.1872998 0.6019289 PEAK1 −0.906413224 0.065373045 0.016666132 −22.73501634 10.2886388 11.9926106 12.5755803 9.1841037 7.4857665 0.6019289 RAD9A −1.163912281 0.04991757 0.006126936 −22.78952839 5.6586086 5.4346801 5.5969865 1.0866873 1.2054667 0.6019289 PRPF40B −1.106827621 0.050608213 0.007389874 −22.78952839 6.4876101 4.9115166 5.5969865 1.0866873 1.2054667 0.6019289 SH3D21 −1.063807516 0.051416052 0.008563749 −22.78952839 4.6394091 6.2280676 5.5969865 1.0866873 1.2054667 0.6019289 FCER1G −0.874306636 0.070926344 0.019902913 −22.78952839 5.982974 3.360637 5.5969865 1.0866873 1.2054667 0.6019289 LOC652276 −1.13134409 0.050131358 0.006733531 −22.91364401 5.3162271 5.3621423 5.7236017 1.0866873 1.2054667 0.6019289 SLC9A5 −1.070382999 0.051355105 0.008342293 −22.91364401 4.7435639 5.6616851 5.7236017 1.0866873 1.2054667 0.6019289 OGDH −1.041913546 0.052218844 0.009257803 −23.13183402 10.7782963 10.4451226 9.5092748 5.9133149 6.4989608 0.6019289 CUL4A −1.049025571 0.051974546 0.009042767 −23.1934646 10.169176 10.5632048 10.5389092 6.7442069 6.0032628 0.6019289 GLRA4 −1.169609548 0.04991757 0.005990532 −23.24818277 5.7445127 5.4346801 5.6099449 1.0866873 1.2054667 0.6019289 MAP2K1 −1.004934549 0.054532631 0.010648319 −23.27370247 12.3447011 11.5734369 12.2916645 8.7595777 7.7510357 0.6019289 DPYSL5 −1.105100662 0.050647945 0.007454064 −23.36299872 5.2636993 5.1480825 6.0721689 1.0866873 1.2054667 0.6019289 LOC284578 −1.081223012 0.051255379 0.008108 −23.36299872 7.3175786 5.1480825 5.5929159 1.6938929 1.2054667 0.6019289 KIAA0284 −0.73788623 0.118499692 0.045980101 −23.38574598 5.7530242 6.3119075 5.5969865 4.6851838 1.2054667 0.6019289 MRPL14 −1.101698193 0.05069779 0.007526278 −23.54252971 11.5506678 12.0162438 11.2520092 7.221194 7.4590463 6.6374655 PAXIP1 −1.128353669 0.050237584 0.006813769 −23.78403042 5.6586086 6.6706551 5.018694 1.0866873 1.2054667 0.6019289 PSPH −1.112033431 0.050440463 0.007231004 −23.78403042 5.6586086 6.0924064 4.9444683 1.0866873 1.2054667 0.6019289 KIAA0664L3 −1.087279832 0.051099543 0.007924256 −23.78403042 5.6586086 6.3520696 4.7549172 1.0866873 1.2054667 0.6019289 VAMP1 −1.033105705 0.052897282 0.009577951 −23.78403042 5.6586086 4.3899364 6.3558005 1.0866873 1.2054667 0.6019289 NFXL1 −0.955465442 0.058423167 0.013009709 −23.78403042 5.6586086 6.0497213 3.9083598 1.0866873 1.2054667 0.6019289 ABCB8 −1.144103261 0.050004604 0.006494423 −23.83480311 5.7530242 5.6616851 5.2176156 1.0866873 1.2054667 0.6019289 C8orf42 −1.019681473 0.053434625 0.009968707 −23.83480311 4.2098819 5.6616851 7.273415 1.0866873 1.2054667 0.6019289 WWOX −1.019283571 0.053434625 0.009976731 −23.83480311 6.4179694 5.6616851 4.2859964 1.0866873 1.2054667 0.6019289 RRN3P1 −0.960986378 0.057805981 0.012720051 −23.83480311 6.0999914 5.6616851 3.9352215 1.0866873 1.2054667 0.6019289 FBXL19 −1.155206384 0.04991757 0.006303458 −23.98790096 5.4911209 5.7897017 5.3892653 1.0866873 1.2054667 0.6019289 ALPK3 −0.776734162 0.101203431 0.035911097 −23.98790096 6.5212096 5.7897017 5.7029118 4.5400907 1.2054667 0.6019289 TCEB3 −1.078344861 0.051291304 0.008173794 −24.06437463 10.5951554 11.3659071 10.9141534 6.7770801 6.6948447 0.6019289 UCN −1.125887673 0.050330336 0.00686833 −24.14838796 6.5540448 5.1957839 5.3892653 1.0866873 1.2054667 0.6019289 RPP25 −1.117890001 0.050341156 0.007068924 −24.14838796 5.3162271 5.1957839 6.3692392 1.0866873 1.2054667 0.6019289 KIAA0513 −1.110972773 0.050482841 0.007254273 −24.14838796 5.2636993 5.1957839 6.0560619 1.0866873 1.2054667 0.6019289 SLED1 −1.106097181 0.050608213 0.007413945 −24.14838796 5.2636993 5.1957839 7.7625708 1.0866873 1.2054667 0.6019289 CHST5 −0.812688426 0.088274767 0.028679291 −24.44449668 7.5951068 7.5477987 7.4018955 5.5826351 2.5373444 2.9363609 PRSS22 −1.12301005 0.050330336 0.006900425 −24.48266733 5.7003762 8.8620252 5.018694 1.0866873 1.2054667 0.6019289 CYP8B1 −1.084420154 0.051255379 0.008003691 −24.48266733 5.7003762 4.7507076 6.0721689 1.0866873 1.2054667 0.6019289 TPD52L1 −0.974181295 0.056729293 0.011988285 −24.48266733 5.7003762 6.537655 3.9352215 1.0866873 1.2054667 0.6019289 PPP1R35 −1.120632432 0.050341156 0.006972639 −24.51659385 5.3162271 6.3520696 5.2176156 1.0866873 1.2054667 0.6019289 NLRC5 −1.119605807 0.050341156 0.006988687 −24.51659385 5.3162271 6.0497213 5.2176156 1.0866873 1.2054667 0.6019289 SLC35F2 −1.114471503 0.050390282 0.007141138 −24.51659385 5.2636993 6.270596 5.2176156 1.0866873 1.2054667 0.6019289 GPAT2 −0.736905429 0.118810891 0.046187114 −24.51659385 8.3973089 6.6385363 5.2176156 5.9133149 1.2054667 0.6019289 B3GAT1 −1.038281538 0.052564289 0.009395812 −24.52573578 4.309025 7.6480149 5.7029118 1.0866873 1.2054667 0.6019289 SYNGAP1 −0.833729585 0.08138461 0.025039718 −24.52573578 6.7650859 2.8096013 5.7029118 1.0866873 1.2054667 0.6019289 NHLH1 −1.15576946 0.04991757 0.006295434 −24.64610095 5.6586086 6.1842483 5.2252164 1.0866873 1.2054667 0.6019289 KIAA1984 −1.121279851 0.050341156 0.006940544 −24.64610095 5.3162271 6.1842483 5.2252164 1.0866873 1.2054667 0.6019289 ZNF687 −1.119417901 0.050341156 0.007004734 −24.64610095 6.4532097 5.297868 5.2252164 1.0866873 1.2054667 0.6019289 FEZ1 −1.116882676 0.050341156 0.007076948 −24.64610095 7.1342805 5.297868 5.2252164 1.0866873 1.2054667 0.6019289 TTC9 −0.786206215 0.097781854 0.033892321 −24.64610095 7.3365789 8.8895842 5.2252164 6.0269554 1.2054667 0.6019289 CTSS −0.784110909 0.098241201 0.034310359 −24.64610095 6.6175557 6.0924064 5.2252164 4.3788962 1.2054667 0.6019289 SIN3A −1.091762716 0.050952718 0.007765386 −24.69302643 12.2229738 11.7872468 12.9059529 7.0161533 8.2799211 7.7187266 C11orf53 −1.159338942 0.04991757 0.006215197 −24.87999641 6.4876101 5.1957839 5.7236017 1.0866873 1.2054667 0.6019289 LAD1 −1.13021942 0.050131358 0.006757603 −24.87999641 5.0569476 8.7686392 5.7236017 1.0866873 1.2054667 0.6019289 VTA1 −0.755390234 0.110198518 0.041092032 −25.12570076 5.8565586 5.8096013 2.3793449 1.0866873 1.2054667 0.6019289 ATP6V0C −1.059373427 0.051695193 0.00872984 −25.22581055 13.7757009 14.4584116 14.4109621 10.4960584 8.2175169 9.7541334 PTPN3 −1.164269615 0.04991757 0.006110888 −25.24324388 5.7445127 7.1748717 5.2252164 1.0866873 1.2054667 0.6019289 C6orf132 −1.161215018 0.04991757 0.006183102 −25.24324388 5.7445127 7.6317881 5.2252164 1.0866873 1.2054667 0.6019289 VNN3 −0.989079617 0.055849348 0.011333547 −25.24324388 5.7445127 7.5477987 3.9083598 1.0866873 1.2054667 0.6019289 DUS2L −0.846442617 0.077676075 0.023049827 −25.24324388 5.7445127 6.3520696 2.9956812 1.0866873 1.2054667 0.6019289 MRPL41 −0.942306481 0.059921626 0.013848191 −25.24721803 11.0541814 10.7903568 10.0002517 6.1323043 1.2054667 8.0564393 NONO −1.090272933 0.051027823 0.0078039 −25.25946532 11.9357942 12.5679039 11.8727987 8.3206874 1.2054667 7.277042 ANKRD34C −1.157038513 0.04991757 0.006271363 −25.31236428 5.2636993 6.4662577 5.5969865 1.0866873 1.2054667 0.6019289 C5orf42 −0.773989939 0.10250289 0.036591511 −25.31236428 5.2636993 6.3520696 7.273415 4.9379926 1.2054667 0.6019289 PTHLH −0.769551426 0.104268882 0.037600899 −25.31236428 5.2636993 7.5987767 6.4105447 5.1531951 1.2054667 0.6019289 NRG1 −1.139781827 0.050038461 0.006574661 −25.39261219 5.7530242 10.3088724 5.2252164 1.0866873 1.2054667 0.6019289 CCHCR1 −1.107130629 0.050608213 0.00738185 −25.39261219 5.7530242 4.8304956 6.4897707 1.0866873 1.2054667 0.6019289 ZNF318 −0.941341464 0.060058355 0.013937254 −25.39261219 5.7530242 3.7709946 6.0721689 1.0866873 1.2054667 0.6019289 PEBP4 −1.182241366 0.049897122 0.005686432 −25.84520947 5.8972917 5.4876732 5.6099449 1.0866873 1.2054667 0.6019289 C4orf42 −1.116176396 0.050341156 0.007101019 −25.84520947 5.8972917 5.3406193 6.1759311 1.6938929 1.2054667 0.6019289 GMPR2 −1.158234865 0.04991757 0.006239268 −25.86164311 5.7794294 5.1957839 6.0540376 1.0866873 1.2054667 0.6019289 FAM83H −1.152062794 0.04991757 0.006375672 −25.86164311 5.7794294 9.0262169 5.2176156 1.0866873 1.2054667 0.6019289 RAPGEF3 −1.093737902 0.050952718 0.007733291 −25.86164311 5.7794294 4.7365865 6.4105447 1.0866873 1.2054667 0.6019289 ANKRD45 −1.170826834 0.04991757 0.005982508 −25.91901741 5.7445127 5.297868 6.0316576 1.0866873 1.2054667 0.6019289 C8orf46 −1.16815955 0.04991757 0.006022627 −25.91901741 6.0548278 5.297868 5.7029118 1.0866873 1.2054667 0.6019289 HDAC4 −1.16704403 0.04991757 0.006062746 −25.91901741 5.7003762 5.297868 6.0125266 1.0866873 1.2054667 0.6019289 RASL11B −0.738524773 0.118195214 0.045803579 −25.91901741 5.982974 5.297868 8.1272196 5.4258059 1.2054667 0.6019289 CHIC1 −1.158675747 0.04991757 0.006231244 −26.03776623 5.3044627 6.1390574 5.5715986 1.0866873 1.2054667 0.6019289 KIF9 −1.167966933 0.04991757 0.006030651 −26.04644157 6.3067721 5.7897017 5.2252164 1.0866873 1.2054667 0.6019289 IDO1 −1.025530753 0.05313101 0.009777742 −26.04644157 4.2098819 5.7897017 6.976024 1.0866873 1.2054667 0.6019289 TSG101 −0.96503207 0.057395438 0.012563588 −26.0802458 12.9045312 11.6204548 10.5779713 7.9254928 1.2054667 8.1996456 ATP6V0B −1.059389265 0.051695193 0.008721817 −26.11464535 12.8711183 12.0699274 12.6175399 7.9107527 1.2054667 8.833074 ARF1 −1.142396882 0.050004604 0.006534542 −26.17442195 16.0512629 15.8505155 15.2326933 11.3959251 10.4200244 11.1404298 FHL3 −0.843210483 0.078689412 0.023625933 −26.2107535 10.145127 10.521976 10.4746101 1.0866873 5.7625232 8.985824 ADAMTSL4 −1.172624556 0.04991757 0.005926342 −26.25095895 5.3162271 6.0604012 5.7236017 1.0866873 1.2054667 0.6019289 POLR2J4 −1.166617304 0.04991757 0.006078793 −26.25095895 5.3162271 5.6616851 6.0125266 1.0866873 1.2054667 0.6019289 TCF24 −1.157153144 0.04991757 0.006263339 −26.25095895 5.3162271 6.0924064 5.5446534 1.0866873 1.2054667 0.6019289 ESRG −1.169004788 0.04991757 0.005998556 −26.4081977 6.2677178 5.8096013 5.2252164 1.0866873 1.2054667 0.6019289 TWIST2 −1.13317049 0.050083269 0.006693413 −26.4081977 4.963444 5.8096013 7.5754206 1.0866873 1.2054667 0.6019289 ZDHHC6 −1.094536014 0.050952718 0.007677124 −26.4081977 6.4532097 5.8096013 4.7244061 1.0866873 1.2054667 0.6019289 RPS6KL1 −1.083832915 0.051255379 0.008027762 −26.4081977 5.982974 5.8096013 4.7244061 1.0866873 1.2054667 0.6019289 BICD1 −1.022620994 0.053385633 0.009880446 −26.4081977 4.309025 5.8096013 6.0721689 1.0866873 1.2054667 0.6019289 MPP6 −1.022052076 0.053385633 0.00988847 −26.4081977 4.309025 5.8096013 6.0540376 1.0866873 1.2054667 0.6019289 LRRC56 −1.185017396 0.049897122 0.005622242 −26.47571031 5.3285264 5.7897017 6.7042855 1.0866873 1.2054667 0.6019289 C2orf82 −1.150781629 0.04991757 0.006391719 −26.47571031 5.3285264 8.6924512 5.6099449 1.0866873 1.2054667 0.6019289 POP1 −1.179510103 0.049897122 0.005814812 −26.60238835 5.3354128 6.4291897 5.7236017 1.0866873 1.2054667 0.6019289 LOC283174 −1.174702071 0.04991757 0.005910294 −26.60238835 5.3354128 7.1970971 5.7029118 1.0866873 1.2054667 0.6019289 ATAD2 −1.164065348 0.04991757 0.006118912 −26.60238835 5.3354128 6.0604012 5.5929159 1.0866873 1.2054667 0.6019289 CSF3R −1.160517669 0.04991757 0.006191126 −26.60238835 5.3354128 5.6616851 8.3020771 1.0866873 1.2054667 0.6019289 TBX19 −0.822405285 0.085361525 0.027042446 −26.64346093 7.5139709 6.8213295 7.8701536 5.6551006 1.2054667 2.7782613 PEX11B −1.176714772 0.04991757 0.005894247 −26.69856636 5.7445127 5.3406193 6.0125266 1.0866873 1.2054667 0.6019289 MAK −1.163704296 0.04991757 0.006142983 −26.69856636 6.1437849 5.3406193 5.5715986 1.0866873 1.2054667 0.6019289 ADCY4 −1.14303484 0.050004604 0.006526518 −26.69856636 6.8201191 5.3406193 5.3892653 1.0866873 1.2054667 0.6019289 TIGD1 −0.796735326 0.094012974 0.03182781 −26.69856636 6.3818471 5.3406193 6.0125266 4.1976103 1.2054667 0.6019289 SMPD2 −1.145402148 0.049952273 0.006462328 −27.0998576 6.0082059 5.3621423 5.3892653 1.0866873 1.2054667 0.6019289 IL10RA −0.822770866 0.085310984 0.026986279 −27.0998576 6.5540448 5.3621423 7.5934735 4.8170878 1.2054667 0.6019289 GLE1 −0.780281415 0.099852653 0.035103105 −27.0998576 7.373845 5.3621423 6.0540376 4.8170878 1.2054667 0.6019289 BDH1 −0.816808778 0.086878366 0.027953944 −27.28188256 5.8565586 2.8096013 6.0316576 1.0866873 1.2054667 0.6019289 APEH −0.880438908 0.069612081 0.019167937 −27.57473528 11.1159753 10.6382319 9.6539332 5.8529567 1.2054667 8.6118796 LARS2 −1.182259354 0.049897122 0.005678408 −27.61416076 5.7003762 7.1060646 5.3892653 1.0866873 1.2054667 0.6019289 BCOR −1.155856283 0.04991757 0.006287411 −27.61416076 6.3818471 5.4346801 5.3892653 1.0866873 1.2054667 0.6019289 SF3B4 −1.036548528 0.05264149 0.009461606 −27.78126148 11.7560442 11.0520503 10.7079526 7.9829919 1.2054667 6.2560101 DCTN2 −1.010937276 0.054161962 0.010370697 −27.80763429 12.3198511 11.8135625 10.9910775 7.0161533 8.6064601 0.6019289 PAPPA −0.919794449 0.06299636 0.015510712 −27.95740662 12.9065195 10.9312788 10.2876614 7.9107527 8.1013608 0.6019289 KCTD18 −0.73851497 0.118195214 0.045811602 −27.99427461 7.0676142 5.6616851 6.0125266 5.2498839 1.2054667 0.6019289 FLJ40852 −1.196939461 0.049809046 0.005389553 −28.06313647 5.8972917 5.3621423 6.2829045 1.0866873 1.2054667 0.6019289 C3orf78 −1.094220702 0.050952718 0.007693172 −28.06313647 5.8972917 6.1842483 4.7244061 1.0866873 1.2054667 0.6019289 SLC29A2 −1.073859749 0.051291304 0.008237984 −28.06313647 5.8972917 6.8774542 4.5083337 1.0866873 1.2054667 0.6019289 EIF1AD −0.970656228 0.057154457 0.012239429 −28.06313647 5.8972917 6.0441977 5.5715986 1.0866873 2.8554202 0.6019289 GJB2 −0.843672168 0.078621688 0.023563348 −28.06313647 5.8972917 6.0726357 2.9956812 1.0866873 1.2054667 0.6019289 PHF1 −1.044979745 0.052154186 0.009175961 −28.31821818 11.8449893 10.4074891 12.472651 7.8808129 7.0213307 0.6019289 RNF217 −1.08136684 0.051255379 0.008091952 −28.45564751 4.6394091 6.0361098 6.0125266 1.0866873 1.2054667 0.6019289 ADIPOQ −0.969902939 0.057171148 0.012287571 −28.45564751 5.982974 6.0361098 3.9083598 1.0866873 1.2054667 0.6019289 THPO −1.194692655 0.049809046 0.005453743 −28.49725711 5.7794294 5.4346801 6.0721689 1.0866873 1.2054667 0.6019289 PPIL6 −1.180807392 0.049897122 0.005774693 −28.49725711 6.7367617 5.4346801 5.6099449 1.0866873 1.2054667 0.6019289 LOC100132774 −1.172016814 0.04991757 0.005942389 −28.49725711 7.3175786 5.4346801 5.5715986 1.0866873 1.2054667 0.6019289 SNHG10 −0.780027773 0.099902938 0.035148038 −28.49725711 6.0548278 5.4346801 7.1074578 1.0866873 4.8088443 0.6019289 CCDC24 −1.061041584 0.051493437 0.008635962 −28.61562105 6.0082059 6.0441977 4.5083337 1.0866873 1.2054667 0.6019289 ZNF408 −1.195166668 0.049809046 0.005429672 −28.81146038 5.3354128 6.0497213 6.0540376 1.0866873 1.2054667 0.6019289 ZNF670 −1.193463811 0.049809046 0.005469791 −28.81146038 5.3285264 6.0361098 6.0540376 1.0866873 1.2054667 0.6019289 NRBF2 −0.800642897 0.092266937 0.030887427 −28.81146038 7.3553323 5.8096013 6.0540376 4.9379926 1.2054667 0.6019289 TIMM17A −1.072733126 0.051291304 0.008270079 −28.85723281 12.16834 12.2063081 11.3213559 8.0246608 7.3174789 0.6019289 APBA1 −0.970822845 0.057122382 0.012221776 −28.93882603 5.982974 6.0604012 3.9083598 1.0866873 1.2054667 0.6019289 CNO −0.816352453 0.086958113 0.028033379 −28.93882603 5.8565586 6.0604012 6.3558005 4.3788962 1.2054667 0.6019289 LXN −0.762186333 0.107099669 0.039413464 −28.93882603 6.8989234 6.0604012 5.5929159 4.9379926 1.2054667 0.6019289 BAG6 −1.114100391 0.050390282 0.007157185 −28.98366791 12.9223282 12.4484855 11.900255 8.0651599 7.8156527 0.6019289 EFHD2 −0.923575336 0.062190894 0.015171307 −29.05843049 11.4220286 12.292707 12.5936325 10.0242622 7.4318221 0.6019289 YTHDF2 −1.138011177 0.050038461 0.006606756 −29.07475291 12.8154861 12.9720526 12.8670565 7.244891 8.922321 8.0053615 SNORA8 −1.196404616 0.049809046 0.005397577 −29.17583876 5.3354128 6.0604012 6.0721689 1.0866873 1.2054667 0.6019289 DCAF12 −1.191433089 0.049809046 0.005501886 −29.17583876 5.3044627 6.0604012 6.0721689 1.0866873 1.2054667 0.6019289 CCNF −1.219574122 0.049622329 0.00505737 −29.1852795 5.6586086 6.0726357 5.7236017 1.0866873 1.2054667 0.6019289 TNPO3 −0.728074845 0.123245219 0.048775576 −29.1852795 5.7003762 6.0726357 6.3558005 5.0495858 1.2054667 0.6019289 FAM70B −1.184302644 0.049897122 0.005638289 −29.56348102 6.4179694 5.4876732 5.5715986 1.0866873 1.2054667 0.6019289 CTRC −1.213952515 0.049622329 0.005145631 −29.58798768 5.7445127 6.0924064 5.5929159 1.0866873 1.2054667 0.6019289 RPP14 −1.22080848 0.049622329 0.005041322 −29.59861642 6.2275774 5.4876732 5.9741452 1.0866873 1.2054667 0.6019289 CD58 −1.107238322 0.050608213 0.007373827 −29.59861642 6.4876101 4.7365865 5.9741452 1.0866873 1.2054667 0.6019289 COPS7B −0.977041821 0.056452334 0.01186472 −29.59861642 6.4179694 3.8720139 5.9741452 1.0866873 1.2054667 0.6019289 WDR27 −0.892178862 0.067585712 0.017964375 −29.59861642 6.1437849 3.3213504 5.9741452 1.0866873 1.2054667 0.6019289 TMPRSS11B −1.177279086 0.04991757 0.005870176 −29.78030621 5.982974 5.1957839 6.3267171 1.0866873 1.2054667 0.6019289 RAB33A −1.208860195 0.04976927 0.005243521 −30.39662533 6.5540448 5.3621423 6.0125266 1.0866873 1.2054667 0.6019289 TRIM44 −1.181352553 0.049897122 0.005734574 −30.39662533 6.4532097 5.1957839 6.0125266 1.0866873 1.2054667 0.6019289 CRABP2 −0.838843328 0.079557207 0.02423654 −30.41814631 11.5270824 14.3938721 14.3065826 11.1003391 6.6002221 9.0375903 WDR90 −1.216307855 0.049622329 0.005097489 −30.56038327 5.7530242 6.1390574 5.5969865 1.0866873 1.2054667 0.6019289 PRICKLE1 −1.035842696 0.052682498 0.009485678 −30.56038327 4.309025 6.1390574 6.0540376 1.0866873 1.2054667 0.6019289 CYTH3 −0.731745138 0.121426098 0.047643425 −30.56038327 6.1437849 6.1390574 6.0540376 5.1531951 1.2054667 0.6019289 COX15 −1.215951041 0.049622329 0.005113536 −30.75447693 6.4876101 5.7897017 5.5446534 1.0866873 1.2054667 0.6019289 ZNF251 −1.171109561 0.04991757 0.005974484 −30.8023879 6.2677178 5.1480825 6.0316576 1.0866873 1.2054667 0.6019289 RLF −1.192296511 0.049809046 0.005485838 −30.89759131 5.2636993 6.0361098 6.3692392 1.0866873 1.2054667 0.6019289 FAM171B −1.106165494 0.050608213 0.007405922 −31.07129311 4.6394091 6.0441977 7.2279137 1.0866873 1.2054667 0.6019289 ARF5 −1.071804786 0.051355105 0.008326246 −31.07129311 6.7078705 6.0441977 4.4498938 1.0866873 1.2054667 0.6019289 SORD −0.971769164 0.056976583 0.012134318 −31.07129311 6.6482929 6.0441977 3.7641245 1.0866873 1.2054667 0.6019289 ADSSL1 −1.197792314 0.049809046 0.005373506 −31.19048223 5.3044627 6.0497213 8.0377511 1.0866873 1.2054667 0.6019289 SLC23A3 −1.109306172 0.050523319 0.00730081 −31.19048223 4.6394091 6.0497213 8.1022182 1.0866873 1.2054667 0.6019289 ZFAT −1.107369817 0.050608213 0.007349755 −31.28393853 6.3067721 4.7365865 6.0540376 1.0866873 1.2054667 0.6019289 MTHFD2L −1.2170735 0.049622329 0.005089465 −31.30107976 6.0548278 7.1293668 5.3892653 1.0866873 1.2054667 0.6019289 TECPR2 −1.18709002 0.049875978 0.005590147 −31.30107976 6.0548278 5.1957839 6.7042855 1.0866873 1.2054667 0.6019289 FBXL6 −1.18119933 0.049897122 0.005758646 −31.30107976 6.0548278 6.1842483 5.2176156 1.0866873 1.2054667 0.6019289 ITGA6 −1.181023415 0.049897122 0.005766669 −31.30107976 6.0548278 8.7980224 5.2252164 1.0866873 1.2054667 0.6019289 MCM4 −1.148160295 0.049952273 0.006430233 −31.30107976 6.0548278 6.7328249 4.9444683 1.0866873 1.2054667 0.6019289 B3GALTL −1.19857482 0.049809046 0.005365482 −31.32786522 5.3162271 6.2280676 6.0560619 1.0866873 1.2054667 0.6019289 IPP −1.182022258 0.049897122 0.005694456 −31.32786522 6.3447976 5.1957839 6.0560619 1.0866873 1.2054667 0.6019289 RHCG −1.177059128 0.04991757 0.005878199 −31.32786522 6.4876101 5.1480825 6.0560619 1.0866873 1.2054667 0.6019289 MTSS1 −1.14578992 0.049952273 0.006454305 −31.32786522 7.0446897 4.9115166 6.0560619 1.0866873 1.2054667 0.6019289 PRSS50 −0.738943623 0.118078127 0.045694456 −31.32786522 1.8744435 6.6385363 6.0560619 1.0866873 1.2054667 0.6019289 TRMT61A −1.042839667 0.052218844 0.009233732 −31.33427445 6.4876101 6.6056864 5.5715986 1.0866873 2.8554202 0.6019289 PRMT6 −0.79735604 0.093829277 0.031726711 −31.33427445 7.5792405 7.4023354 5.5715986 5.6551006 1.2054667 0.6019289 EDC4 −1.259207151 0.04958755 0.00447966 −31.42223417 6.1437849 6.0604012 5.7236017 1.0866873 1.2054667 0.6019289 TPCN2 −0.779496397 0.100080374 0.035314932 −31.42223417 6.186289 6.0604012 2.3793449 1.0866873 1.2054667 0.6019289 LOC100507032 −1.202740978 0.049809046 0.005333387 −31.53280526 5.3162271 6.1842483 6.1759311 1.0866873 1.2054667 0.6019289 C3orf62 −1.105580696 0.050608213 0.007438017 −31.53280526 4.7435639 6.1842483 6.0721689 1.0866873 1.2054667 0.6019289 UBR1 −1.225656217 0.049622329 0.004969109 −31.57743994 6.186289 5.4876732 6.0721689 1.0866873 1.2054667 0.6019289 RETSAT −1.136774466 0.050038461 0.006630827 −31.57743994 6.186289 4.9115166 6.1759311 1.0866873 1.2054667 0.6019289 CLCN5 −1.237209001 0.04958755 0.004776539 −31.68983724 6.2677178 6.0726357 5.5446534 1.0866873 1.2054667 0.6019289 TARP −1.063942599 0.051416052 0.008555725 −31.68983724 4.2634629 6.0726357 8.5897647 1.0866873 1.2054667 0.6019289 HIST1H1C −0.883810095 0.068943426 0.018824521 −31.68983724 7.0676142 6.0726357 2.9956812 1.0866873 1.2054667 0.6019289 ARHGEF35 −1.217577656 0.049622329 0.005081441 −31.80070703 5.7794294 7.1293668 5.5929159 1.0866873 1.2054667 0.6019289 SEPX1 −0.79324218 0.094987603 0.032376635 −31.80070703 8.3699022 7.3237074 5.5929159 1.0866873 6.0753543 0.6019289 FBXO25 −1.224927673 0.049622329 0.004985156 −31.89056092 6.3818471 5.8096013 5.5969865 1.0866873 1.2054667 0.6019289 ACVR2B −1.208399188 0.04976927 0.005267592 −31.89056092 6.3067721 5.6616851 5.5969865 1.0866873 1.2054667 0.6019289 H2AFZ −0.910542856 0.064737869 0.016312284 −32.03739462 13.0440078 14.1167381 14.5562622 9.1150532 11.4398374 7.6538745 GMPPB −0.785968482 0.097841721 0.033930835 −32.17829531 8.9779688 7.3237074 5.6099449 6.3662802 1.2054667 0.6019289 PPARGC1B −1.212919925 0.049694878 0.00518575 −32.29645787 6.0999914 5.3406193 6.6706745 1.0866873 1.2054667 0.6019289 RPS6KB2 −1.046583191 0.052154186 0.009135842 −32.29645787 6.0999914 6.537655 4.2859964 1.0866873 1.2054667 0.6019289 DNAJC9 −1.261701619 0.04958755 0.004423494 −32.49420971 6.2275774 6.0497213 5.7236017 1.0866873 1.2054667 0.6019289 PNLDC1 −1.110250676 0.050482841 0.007278344 −32.49420971 6.2275774 4.7365865 6.1759311 1.0866873 1.2054667 0.6019289 TRIT1 −1.280524846 0.04958755 0.004118591 −32.50525139 5.8565586 6.2280676 6.0540376 1.0866873 1.2054667 0.6019289 SNAI3 −1.184676183 0.049897122 0.005630266 −33.18294662 5.2636993 6.1390574 9.6879398 1.0866873 1.2054667 0.6019289 MTO1 −1.228329408 0.049622329 0.004945037 −33.28221884 5.6586086 5.7897017 7.0300422 1.0866873 1.2054667 0.6019289 C12orf76 −1.237429114 0.04958755 0.004760491 −33.29185955 6.1437849 5.4876732 6.4897707 1.0866873 1.2054667 0.6019289 SOX7 −1.259545707 0.04958755 0.004463612 −33.35326768 6.4876101 5.6616851 6.0721689 1.0866873 1.2054667 0.6019289 CPEB1 −1.223136817 0.049622329 0.005017251 −33.35326768 5.7445127 5.6616851 7.0563116 1.0866873 1.2054667 0.6019289 VPS13B −0.763276117 0.10685386 0.039164728 −33.35326768 6.5212096 5.6616851 6.9199049 5.2498839 1.2054667 0.6019289 APBB3 −0.933940862 0.060990824 0.014438739 −33.47771963 6.2677178 6.270596 7.2279137 4.1976103 1.2054667 0.6019289 GALM −0.804296008 0.090718963 0.030062585 −33.47771963 5.7003762 6.270596 8.0638846 5.2498839 1.2054667 0.6019289 EXT1 −1.04765716 0.052136699 0.009105352 −33.49064808 11.7727085 12.5927431 12.0540334 6.988347 1.2054667 9.0248218 IYD −1.266906035 0.04958755 0.004359304 −33.76455956 6.2677178 5.6616851 6.2829045 1.0866873 1.2054667 0.6019289 RASSF6 −0.933318064 0.061078464 0.014507743 −34.03579391 7.6263253 7.7863852 7.5934735 5.4258059 2.5373444 0.6019289 WDPCP −1.260253752 0.04958755 0.004447565 −34.23881777 7.0446897 6.1842483 5.5969865 1.0866873 1.2054667 0.6019289 PFN1P2 −1.260215045 0.04958755 0.004455589 −34.23881777 6.7078705 6.1842483 5.5969865 1.0866873 1.2054667 0.6019289 MRPS22 −1.22770632 0.049622329 0.004953061 −34.23881777 7.2788106 6.1842483 5.3892653 1.0866873 1.2054667 0.6019289 MOSPD3 −1.201089531 0.049809046 0.005349434 −34.23881777 6.8989234 6.1842483 5.2176156 1.0866873 1.2054667 0.6019289 LTB4R −1.128416792 0.050237584 0.006805745 −34.23881777 6.8468682 6.1842483 4.7549172 1.0866873 1.2054667 0.6019289 NQO1 −1.01812465 0.053512074 0.010042526 −34.23881777 7.373845 6.1842483 3.9352215 1.0866873 1.2054667 0.6019289 ASAP3 −1.08124665 0.051255379 0.008099976 −34.28728281 6.186289 4.4133226 7.1074578 1.0866873 1.2054667 0.6019289 KCNIP3 −1.274145011 0.04958755 0.004214876 −34.32012535 7.2983248 6.1842483 5.7029118 1.0866873 1.2054667 0.6019289 LMO2 −1.267546241 0.04958755 0.00435128 −34.32012535 7.021395 6.0924064 5.7029118 1.0866873 1.2054667 0.6019289 MAPKBP1 −1.232379554 0.04958755 0.004832705 −34.32012535 5.7530242 6.7020747 5.7029118 1.0866873 1.2054667 0.6019289 NDST2 −0.822231852 0.085361525 0.027074541 −34.32012535 7.4279993 7.0089004 5.7029118 5.2498839 1.2054667 0.6019289 ANKRD13C −1.27341299 0.04958755 0.004230924 −34.80566947 5.7794294 6.0604012 6.3267171 1.0866873 1.2054667 0.6019289 RPL36A −1.269310645 0.04958755 0.004319185 −34.80566947 5.7445127 6.0726357 6.3267171 1.0866873 1.2054667 0.6019289 ZNF623 −1.214978782 0.049622329 0.005137607 −35.2827259 6.2275774 5.3406193 6.3558005 1.0866873 1.2054667 0.6019289 DPY19L2P2 −1.183217577 0.049897122 0.005662361 −35.2827259 6.2275774 5.1480825 6.3558005 1.0866873 1.2054667 0.6019289 LOC440896 −1.255516058 0.04958755 0.00454385 −35.29471513 8.085359 6.2280676 5.6099449 1.0866873 1.2054667 0.6019289 BNIP1 −1.23138098 0.04958755 0.004856776 −35.29471513 6.8989234 6.2280676 5.3892653 1.0866873 1.2054667 0.6019289 BTNL9 −1.06045766 0.051535817 0.008660034 −35.29471513 4.309025 6.2280676 6.7042855 1.0866873 1.2054667 0.6019289 ZNF502 −1.01282874 0.054044749 0.010250341 −35.29471513 6.9736463 6.2280676 3.9352215 1.0866873 1.2054667 0.6019289 THBS3 −1.264919754 0.04958755 0.004375351 −35.32417139 5.7445127 6.0361098 7.273415 1.0866873 1.2054667 0.6019289 SERPINB6 −0.971103796 0.057101475 0.012198508 −35.39604594 11.2844606 10.4146205 10.5083079 8.5376958 5.3627916 0.6019289 TMEM62 −0.793120439 0.094990031 0.032400706 −35.51444079 7.1123989 6.0726357 6.3558005 5.2498839 1.2054667 0.6019289 DOCK7 −1.272727649 0.04958755 0.004238947 −35.53319016 5.7530242 6.7328249 6.0560619 1.0866873 1.2054667 0.6019289 LRFN4 −1.26943836 0.04958755 0.004303137 −35.53319016 5.7530242 7.1748717 6.0560619 1.0866873 1.2054667 0.6019289 SRL −1.268528049 0.04958755 0.004343256 −36.35063649 8.518743 6.270596 5.7236017 1.0866873 1.2054667 0.6019289 ZSCAN21 −1.175037579 0.04991757 0.005902271 −36.35063649 6.8731305 6.270596 5.018694 1.0866873 1.2054667 0.6019289 SYNJ2 −1.112777237 0.050440463 0.007198909 −36.35063649 4.6820765 6.270596 6.4507011 1.0866873 1.2054667 0.6019289 PCK2 −1.230799732 0.04958755 0.004872824 −36.39523994 6.3818471 6.3911446 5.3892653 1.0866873 1.2054667 0.6019289 ZHX1-C8ORF76 −1.261405628 0.04958755 0.004431517 −36.44812728 5.982974 5.7897017 7.5386226 1.0866873 1.2054667 0.6019289 B4GALNT4 −1.275059723 0.04958755 0.004174757 −36.66209183 5.6586086 7.4949535 6.2829045 1.0866873 1.2054667 0.6019289 CLDN15 −1.329566658 0.04958755 0.003613095 −36.88795755 6.0999914 6.1842483 6.4105447 1.0866873 1.2054667 0.6019289 CHEK1 −0.901713374 0.066175504 0.017023189 −36.88795755 6.3818471 7.08238 6.4105447 4.5400907 1.2054667 0.6019289 FAM178A −0.788886416 0.096395323 0.033205488 −36.88795755 6.8201191 6.0361098 6.4105447 5.1531951 1.2054667 0.6019289 JRK −0.832007614 0.082058134 0.025363075 −36.9746458 8.1076531 7.1293668 8.0638846 6.2771857 2.8554202 0.6019289 PARP16 −0.877918856 0.070255881 0.019571532 −37.07828671 6.4179694 6.0361098 7.4620859 4.6851838 1.2054667 0.6019289 SPATA5 −1.255842775 0.04958755 0.004535826 −37.27366545 6.3067721 6.4662577 5.5446534 1.0866873 1.2054667 0.6019289 COLQ −1.231269334 0.04958755 0.0048648 −37.27366545 6.3067721 5.3621423 6.7692467 1.0866873 1.2054667 0.6019289 ZNF710 −1.128926595 0.050187311 0.006789698 −37.27366545 6.3067721 6.7629335 4.7244061 1.0866873 1.2054667 0.6019289 C1orf212 −0.897611169 0.066733582 0.017375431 −37.36778042 7.0676142 6.4291897 6.0540376 4.3788962 1.2054667 0.6019289 SCYL2 −1.284354792 0.04958755 0.00409452 −37.40657992 6.5540448 6.3119075 5.7029118 1.0866873 1.2054667 0.6019289 STK11IP −1.270738335 0.04958755 0.00428709 −37.40657992 6.8731305 6.3119075 5.5969865 1.0866873 1.2054667 0.6019289 HSF4 −1.065861929 0.051378258 0.008475487 −37.40657992 4.2098819 6.3119075 7.5571389 1.0866873 1.2054667 0.6019289 NPAS2 −1.007449898 0.054397005 0.010546417 −37.40657992 6.6175557 6.3119075 3.9352215 1.0866873 1.2054667 0.6019289 FAM59B −1.231743915 0.04958755 0.004840729 −37.7925454 7.2186326 5.3406193 6.3267171 1.0866873 1.2054667 0.6019289 KIF1A −1.254995019 0.04958755 0.004559897 −38.1769435 5.8565586 8.6767186 6.0125266 1.0866873 1.2054667 0.6019289 SAMD5 −0.999252242 0.055166136 0.010950814 −38.1769435 5.8565586 7.1060646 6.976024 3.7493131 1.2054667 0.6019289 NPHP4 −1.302686423 0.04958755 0.003885902 −38.26915924 6.3447976 5.7897017 6.6706745 1.0866873 1.2054667 0.6019289 C9orf89 −0.841722311 0.078901035 0.023763941 −38.29158551 10.2314132 9.9743873 10.0760433 4.8170878 1.2054667 9.0502468 GUF1 −0.767488199 0.104951556 0.038107197 −38.34033568 7.0676142 6.4662577 6.2829045 5.6551006 1.2054667 0.6019289 ABCB4 −1.179716366 0.049897122 0.005798764 −38.46254365 5.0569476 6.3520696 6.564874 1.0866873 1.2054667 0.6019289 RHOF −1.062277841 0.051458876 0.00858782 −38.46254365 4.309025 6.3520696 6.564874 1.0866873 1.2054667 0.6019289 PRC1 −1.161495204 0.04991757 0.006167054 −38.56214049 6.7928648 4.9115166 6.3558005 1.0866873 1.2054667 0.6019289 TNFRSF12A −1.137824052 0.050038461 0.00661478 −38.70541355 11.1337373 13.1996494 12.0637791 1.0866873 6.9843361 7.925186 BHLHE22 −1.310318837 0.04958755 0.003821712 −39.26466745 6.3818471 5.8096013 7.1074578 1.0866873 1.2054667 0.6019289 SLC25A22 −1.271236738 0.04958755 0.004279066 −39.26466745 6.3818471 6.6056864 5.5929159 1.0866873 1.2054667 0.6019289 PROM1 −1.231696113 0.04958755 0.004848752 −39.26466745 6.3818471 8.7907325 5.3892653 1.0866873 1.2054667 0.6019289 SUV420H1 −0.802865156 0.091189447 0.030346626 −39.27019233 5.8972917 6.8213295 6.8006628 5.1531951 1.2054667 0.6019289 ACHE −1.307305838 0.04958755 0.003853807 −39.31290468 6.0548278 6.5023977 6.0125266 1.0866873 1.2054667 0.6019289 FLJ32224 −1.163716343 0.04991757 0.006134959 −39.51852612 6.5861495 6.3911446 4.9444683 1.0866873 1.2054667 0.6019289 ZNF500 −0.828724094 0.082955513 0.02590548 −39.82887879 6.5212096 6.8774542 6.2829045 5.0495858 1.2054667 0.6019289 GDNF −0.757422237 0.109447664 0.040601781 −39.82887879 6.5212096 6.0924064 7.0563116 5.6551006 1.2054667 0.6019289 ITGB5 −1.196102237 0.049809046 0.005413624 −39.97341997 14.8424014 14.590751 13.3011693 9.5214323 8.5186068 9.2054107 PIKFYVE −1.302147289 0.04958755 0.003893926 −40.05352667 5.7794294 6.537655 6.4105447 1.0866873 1.2054667 0.6019289 PCMT1 −1.135012583 0.050038461 0.006662922 −40.25016683 12.0285424 11.7397701 11.5042513 6.4088472 1.2054667 7.925186 SETMAR −1.215484752 0.049622329 0.005129584 −40.26018907 6.4179694 6.7924268 5.2252164 1.0866873 1.2054667 0.6019289 PSAT1 −0.812862157 0.088193489 0.02863837 −40.26018907 6.4179694 7.4213407 2.1654208 1.0866873 1.2054667 0.6019289 ERMP1 −1.179438344 0.049897122 0.005822836 −40.28548644 6.5212096 6.537655 5.018694 1.0866873 1.2054667 0.6019289 G0S2 −0.840819309 0.079098445 0.023875471 −40.30282763 7.7590076 8.0533052 7.8701536 6.6046733 2.5373444 0.6019289 XPO4 −1.274663474 0.04958755 0.004198829 −40.57452592 6.6175557 6.4291897 5.5969865 1.0866873 1.2054667 0.6019289 NRP2 −1.187535678 0.049875978 0.005574099 −40.57452592 7.1342805 6.4291897 5.018694 1.0866873 1.2054667 0.6019289 ASRGL1 −1.3620059 0.04958755 0.00332424 −40.74576236 6.5540448 6.1842483 6.3692392 1.0866873 1.2054667 0.6019289 ANKAR −1.315309508 0.04958755 0.00377357 −40.74576236 6.5540448 6.0726357 6.0560619 1.0866873 1.2054667 0.6019289 PAN3-AS1 −0.87914413 0.069835403 0.019332424 −40.74576236 6.5540448 6.0924064 6.8910052 4.5400907 1.2054667 0.6019289 CDH13 −1.310142409 0.04958755 0.003829736 −41.05275997 6.4532097 5.8096013 6.564874 1.0866873 1.2054667 0.6019289 RPS6KA5 −0.82227276 0.085361525 0.027066517 −41.05275997 6.2275774 6.5720715 6.564874 4.9379926 1.2054667 0.6019289 SLAMF1 −1.145061522 0.049952273 0.006470352 −41.25572316 6.4532097 4.7365865 7.1323668 1.0866873 1.2054667 0.6019289 LRP8 −1.088987639 0.051077531 0.007860066 −41.25572316 6.4532097 6.6056864 4.4498938 1.0866873 1.2054667 0.6019289 CCDC22 −0.82134412 0.085414368 0.027187676 −41.25808009 7.6416849 6.5720715 6.4105447 5.5826351 1.2054667 0.6019289 XRRA1 −0.819989981 0.085792514 0.027378641 −41.25808009 6.5861495 6.5720715 6.1759311 4.9379926 1.2054667 0.6019289 SCAND2 −0.727611054 0.123357599 0.048946482 −41.32802826 8.2244688 8.3396934 8.313014 7.522033 2.8554202 2.9363609 REPIN1 −1.010947882 0.054161962 0.010362674 −41.41765033 11.4797912 11.4527639 10.7038034 6.0805901 1.2054667 8.4493889 CACNA1H −1.278012966 0.04958755 0.004134639 −41.63054178 7.463005 6.4662577 5.5715986 1.0866873 1.2054667 0.6019289 SCFD2 −1.346879903 0.04958755 0.003468667 −42.09399983 6.4179694 6.0441977 6.6010094 1.0866873 1.2054667 0.6019289 STC2 −1.038058792 0.052564289 0.009403835 −42.25126886 6.4876101 7.5649923 3.9352215 1.0866873 1.2054667 0.6019289 NR5A2 −0.953561114 0.058581361 0.013102784 −42.25126886 6.4876101 6.270596 6.5278107 1.0866873 3.9031434 0.6019289 LOC100133091 −1.261717222 0.04958755 0.00441547 −42.31459405 5.4911209 6.7020747 6.4897707 1.0866873 1.2054667 0.6019289 INPP5D −1.298416296 0.04958755 0.003942069 −42.40836537 6.0082059 6.270596 8.8671038 1.0866873 1.2054667 0.6019289 REXO4 −0.916377462 0.063342057 0.015710503 −42.53556349 8.1830764 8.2888552 6.0125266 5.5826351 1.2054667 0.6019289 SLC35C1 −0.752574811 0.111643653 0.041839044 −42.53556349 6.9242634 7.4586165 6.0125266 6.0805901 1.2054667 0.6019289 NSMAF −1.318446245 0.04958755 0.003749499 −42.57955515 6.6175557 5.8096013 6.6010094 1.0866873 1.2054667 0.6019289 ZBTB39 −1.296949779 0.04958755 0.00396614 −42.68657254 6.6482929 6.5023977 5.7029118 1.0866873 1.2054667 0.6019289 CWF19L1 −1.171736265 0.04991757 0.005958437 −42.68657254 6.7078705 6.5023977 4.9444683 1.0866873 1.2054667 0.6019289 EIF4EBP1 −1.009282897 0.054296381 0.010482227 −42.68657254 7.2590288 6.5023977 3.7641245 1.0866873 1.2054667 0.6019289 GPRIN1 −1.34524293 0.04958755 0.003492739 −43.10336796 6.3818471 6.7924268 6.0316576 1.0866873 1.2054667 0.6019289 ISLR2 −0.765630944 0.105690271 0.038530851 −43.13525319 7.2389721 6.0726357 6.6362622 5.7241063 1.2054667 0.6019289 DAGLA −1.321482684 0.04958755 0.003701356 −43.24682539 6.5212096 5.8096013 7.1809309 1.0866873 1.2054667 0.6019289 LOC401127 −1.318003394 0.04958755 0.003757522 −43.24682539 6.5212096 5.8096013 7.6463154 1.0866873 1.2054667 0.6019289 ZNF589 −1.154505115 0.04991757 0.006327529 −43.24682539 6.5212096 4.8079702 6.861515 1.0866873 1.2054667 0.6019289 FAM115C −0.935446678 0.060847991 0.01432079 −43.49646331 6.6482929 6.3911446 7.3812609 4.5400907 1.2054667 0.6019289 RSPRY1 −1.32103371 0.04958755 0.00370938 −43.64644834 6.1437849 6.0497213 7.1074578 1.0866873 1.2054667 0.6019289 SFXN1 −1.346500584 0.04958755 0.003484715 −43.77722656 8.2039211 6.537655 6.0540376 1.0866873 1.2054667 0.6019289 POLR1C −1.334331058 0.04958755 0.003581 −43.77722656 6.2677178 7.2405467 6.0540376 1.0866873 1.2054667 0.6019289 POU3F1 −1.315525305 0.04958755 0.003765546 −43.80121316 6.0548278 6.3119075 8.5253933 1.0866873 1.2054667 0.6019289 C16orf54 −0.742108103 0.116965003 0.044718768 −43.80121316 6.0548278 6.7328249 6.976024 5.8529567 1.2054667 0.6019289 FAM122B −1.344170962 0.04958755 0.003500762 −43.83869544 7.2186326 6.3520696 6.0560619 1.0866873 1.2054667 0.6019289 AGTRAP −0.74263594 0.11661419 0.044546257 −43.83869544 8.6836453 8.2035936 6.0560619 7.522033 1.2054667 0.6019289 ATP6V0A2 −0.738848932 0.118078127 0.045727353 −43.83869544 7.7015384 7.282726 6.0560619 6.5675757 1.2054667 0.6019289 SGIP1 −1.336401969 0.04958755 0.003548905 −43.97075077 7.2788106 6.0604012 6.2829045 1.0866873 1.2054667 0.6019289 CLEC4E −1.106224223 0.050608213 0.007397898 −44.24239204 6.5540448 4.3513152 8.1997247 1.0866873 1.2054667 0.6019289 TARBP2 −1.312720057 0.04958755 0.003805665 −44.33087692 7.2788106 6.0726357 6.0721689 1.0866873 1.2054667 0.6019289 SLC7A5 −1.0737793 0.051291304 0.008246008 −44.34220984 12.236315 13.1215399 11.8653879 9.3352666 1.2054667 6.7657063 BRAP −1.360198297 0.04958755 0.003340287 −44.34522153 7.2590288 6.0726357 6.4897707 1.0866873 1.2054667 0.6019289 HGF −0.845168108 0.077954823 0.023248014 −44.34522153 8.234634 6.0726357 6.8910052 5.5826351 1.2054667 0.6019289 QPRT −0.819629312 0.085991355 0.027476531 −44.34522153 6.8989234 6.0726357 6.976024 5.2498839 1.2054667 0.6019289 PDE4B −1.216104931 0.049622329 0.005105512 −44.41337869 6.6783891 5.1957839 6.6010094 1.0866873 1.2054667 0.6019289 DDIT4L −0.940386813 0.060114874 0.013983792 −44.57573489 6.8201191 3.3213504 6.564874 1.0866873 1.2054667 0.6019289 LOC440944 −0.863501351 0.07316741 0.020872984 −44.81437991 8.3882311 8.101237 8.4180516 6.9015613 2.9023413 0.6019289 C8orf73 −1.329536207 0.04958755 0.003621119 −45.19409703 6.0999914 6.1390574 6.8314096 1.0866873 1.2054667 0.6019289 CAMSAP1 −0.780687291 0.099766818 0.03502367 −45.21779682 6.2275774 7.6317881 6.7042855 5.9133149 1.2054667 0.6019289 FCHSD1 −1.148806111 0.049952273 0.00642221 −45.23796818 6.5861495 4.7365865 6.976024 1.0866873 1.2054667 0.6019289 MMP10 −1.274777825 0.04958755 0.004190805 −45.70632956 7.4971815 5.4876732 6.6010094 1.0866873 1.2054667 0.6019289 GNL3L −0.819243207 0.08612692 0.027570408 −45.75827541 8.2647067 8.0533052 7.8402254 7.0702087 2.5373444 0.6019289 TNFRSF25 −0.967924895 0.057313185 0.012451256 −46.12120124 6.4532097 6.7328249 9.0869404 4.9379926 1.2054667 0.6019289 IQSEC2 −1.368007005 0.04958755 0.00326005 −46.2335532 6.6175557 6.0497213 7.273415 1.0866873 1.2054667 0.6019289 KIAA0415 −0.819411638 0.086019863 0.027507823 −46.25908547 6.5861495 8.0037262 6.7371315 5.9712523 1.2054667 0.6019289 KDM2B −0.789394032 0.096229838 0.033085132 −46.58701386 6.1437849 6.8496647 7.481604 5.7899671 1.2054667 0.6019289 C8orf86 −1.180045145 0.049897122 0.005782717 −47.11544113 10.3669723 10.806712 10.1109305 6.4088472 4.8088443 0.6019289 DTNB −1.347770316 0.04958755 0.003444596 −47.22914655 6.6482929 8.1129752 5.9741452 1.0866873 1.2054667 0.6019289 PRSS53 −1.290519788 0.04958755 0.004022306 −47.22914655 6.6482929 7.1522986 5.5715986 1.0866873 1.2054667 0.6019289 MGC12982 −1.098430029 0.050846008 0.007590468 −47.22914655 6.6482929 4.3899364 6.976024 1.0866873 1.2054667 0.6019289 BFAR −0.730330556 0.122185801 0.048102383 −47.30038439 6.5861495 6.8213295 6.7692467 6.2304884 1.2054667 0.6019289 SLC18A2 −1.387209714 0.04958755 0.003115622 −47.63672085 6.6175557 7.3830764 6.1759311 1.0866873 1.2054667 0.6019289 MID2 −1.393121706 0.04958755 0.003059456 −47.96691659 7.2590288 6.6706551 6.1759311 1.0866873 1.2054667 0.6019289 SLC27A4 −0.915008348 0.063651711 0.015839685 −47.96691659 7.1980024 6.6706551 2.9956812 1.0866873 1.2054667 0.6019289 DZIP1L −1.31424787 0.04958755 0.003789617 −47.96756191 5.7003762 7.3437697 6.6706745 1.0866873 1.2054667 0.6019289 MADD −1.307318272 0.04958755 0.003845784 −47.96756191 7.1980024 5.6616851 6.6706745 1.0866873 1.2054667 0.6019289 NPW −1.385451107 0.04958755 0.003139693 −47.97996091 6.186289 7.2189854 6.564874 1.0866873 1.2054667 0.6019289 FGFR3 −0.989652067 0.055830986 0.011294231 −47.97996091 6.186289 7.1970971 9.451056 4.9379926 1.2054667 0.6019289 ABCA1 −0.73787005 0.118499692 0.045988125 −47.97996091 6.186289 6.8774542 7.8402254 1.0866873 6.5504789 0.6019289 PDZK1IP1 −1.246212416 0.04958755 0.004664206 −48.08110433 6.7928648 8.225386 5.5969865 1.6938929 1.2054667 0.6019289 LOC349196 −0.776405308 0.101218075 0.035949611 −48.08110433 6.7928648 6.6056864 8.7909179 6.7770801 1.2054667 0.6019289 LYSMD2 −1.296386231 0.04958755 0.003974164 −48.22474775 6.6783891 7.2189854 5.5929159 1.0866873 1.2054667 0.6019289 LMBR1L −0.892364357 0.067567176 0.017940303 −48.99805002 6.8201191 6.5023977 7.6113033 5.1531951 1.2054667 0.6019289 WDR55 −0.801269748 0.091903585 0.030705288 −48.99805002 6.8201191 6.7328249 6.8910052 5.7241063 1.2054667 0.6019289 HLA-DMA −1.363416853 0.04958755 0.003308192 −49.02301788 6.0082059 6.7020747 6.8314096 1.0866873 1.2054667 0.6019289 NRN1L −1.376997207 0.04958755 0.003187836 −49.09819765 6.9491661 6.0726357 6.7042855 1.0866873 1.2054667 0.6019289 ITGB7 −0.945047362 0.059600929 0.01368932 −49.3729357 6.2275774 7.9653908 9.729351 5.9133149 1.2054667 0.6019289 SCNN1D −1.188371026 0.049809046 0.005550028 −49.38301053 4.963444 6.7629335 6.8314096 1.0866873 1.2054667 0.6019289 MLLT4 −0.740979105 0.117645691 0.045075824 −49.38301053 6.5212096 7.2617905 6.8314096 6.3662802 1.2054667 0.6019289 PI4K2A −1.236807626 0.04958755 0.004784562 −50.14064835 12.9053268 13.4003826 14.1951669 8.5472581 7.8774997 0.6019289 LOC286467 −1.388247678 0.04958755 0.003099575 −50.21597183 6.7367617 6.1390574 6.861515 1.0866873 1.2054667 0.6019289 TFAP2A −1.139489964 0.050038461 0.006582685 −50.21597183 6.7367617 8.2784691 4.5083337 1.0866873 1.2054667 0.6019289 EXD2 −0.77576077 0.101475033 0.036091631 −50.22884531 8.1296079 7.4949535 6.7371315 1.0866873 1.2054667 6.8257955 HHIPL1 −0.788475009 0.096602025 0.033340287 −50.4243366 7.9805393 6.8496647 6.861515 6.4903918 1.2054667 0.6019289 CDC42EP2 −0.757540682 0.109414016 0.040571291 −50.4243366 7.7015384 6.3911446 6.861515 6.3662802 1.2054667 0.6019289 VAMP3 −0.740246657 0.117838959 0.045241916 −50.4243366 8.1830764 6.3520696 6.861515 6.7442069 1.2054667 0.6019289 TMEM222 −1.082457507 0.051255379 0.008059857 −50.5178631 11.7356106 11.4212449 10.7826361 8.1174489 5.7625232 0.6019289 DNAJB13 −1.374263704 0.04958755 0.003211907 −50.76593604 6.2677178 7.2405467 6.3558005 1.0866873 1.2054667 0.6019289 MEX3A −0.889466152 0.068025256 0.018218727 −50.76593604 6.2677178 7.5987767 7.7784397 5.5063453 1.2054667 0.6019289 PPP1R13B −1.346693475 0.04958755 0.003476691 −50.867318 6.3067721 6.270596 8.313014 1.0866873 1.2054667 0.6019289 NRM −0.739167854 0.118017692 0.045611811 −50.867318 7.7015384 6.270596 7.2508437 1.0866873 6.7399276 0.6019289 RABEPK −0.777610808 0.100926453 0.03572976 −50.98452513 7.1770729 6.8774542 6.564874 6.0269554 1.2054667 0.6019289 NCAPD3 −1.364776213 0.04958755 0.003276097 −51.2115939 6.7650859 7.0338116 5.9741452 1.0866873 1.2054667 0.6019289 EDNRB −1.161692014 0.04991757 0.006159031 −51.22922893 16.0242776 14.3204681 14.5115642 10.195188 10.3453823 7.6538745 KCNC4 −1.282841303 0.04958755 0.004110567 −51.35950412 5.4911209 7.1060646 6.7692467 1.0866873 1.2054667 0.6019289 OTUD4 −1.165494096 0.04991757 0.006086817 −51.8362882 11.5363574 12.2646977 12.727901 8.2753779 5.3627916 6.5688072 GHRLOS2 −1.421911546 0.04958755 0.002866886 −52.15895996 6.3067721 6.7629335 7.3390847 1.0866873 1.2054667 0.6019289 ABTB2 −0.85833366 0.07443975 0.021473963 −52.15895996 6.3067721 7.7111563 8.1272196 6.0269554 1.2054667 0.6019289 FLVCR1 −0.822668496 0.085317325 0.027002327 −52.15895996 6.3067721 7.1060646 7.0300422 5.5063453 1.2054667 0.6019289 VILL −1.415130664 0.04958755 0.002907005 −52.34495401 6.6783891 6.3119075 7.3175252 1.0866873 1.2054667 0.6019289 EIF2B2 −1.411559831 0.04958755 0.002955147 −52.34495401 7.2590288 6.3119075 6.6362622 1.0866873 1.2054667 0.6019289 CXXC1P1 −0.795326087 0.094440529 0.03205729 −52.34495401 7.2983248 6.3119075 7.2508437 5.9712523 1.2054667 0.6019289 KIFC2 −1.394743823 0.04958755 0.003035385 −52.50701226 6.1437849 6.8213295 6.9199049 1.0866873 1.2054667 0.6019289 C9orf72 −0.854566499 0.075433888 0.022049266 −52.50701226 7.1980024 6.7924268 6.9199049 5.5063453 1.2054667 0.6019289 SAA1 −1.139465631 0.050038461 0.006590708 −52.86321164 11.637507 13.0817734 9.8877056 5.9133149 1.2054667 7.4777211 STK16 −1.386577772 0.04958755 0.003123646 −52.8850554 7.2389721 6.3911446 6.3267171 1.0866873 1.2054667 0.6019289 MRPL48 −1.192094794 0.049809046 0.005493862 −52.8850554 7.7305591 7.3635569 6.3267171 3.1012538 1.2054667 0.6019289 RRAGD −0.784928469 0.098230159 0.034177164 −52.8850554 8.254752 7.9523826 6.3267171 6.9310735 1.2054667 0.6019289 SEMA3F −1.404816045 0.04958755 0.002987242 −53.20285626 6.8201191 7.3033622 6.1759311 1.0866873 1.2054667 0.6019289 NOL7 −1.089665965 0.051027823 0.007835995 −53.24751041 6.9736463 6.8213295 4.2859964 1.0866873 1.2054667 0.6019289 SHISA4 −0.758589669 0.109048772 0.040320148 −53.82261845 7.7448535 6.3520696 7.3812609 1.0866873 6.6948447 0.6019289 DNER −1.427505584 0.04958755 0.002834791 −53.96198945 7.2788106 6.7328249 6.3558005 1.0866873 1.2054667 0.6019289 CTNNBIP1 −0.914190684 0.063789541 0.01590548 −54.46699285 7.3365789 7.5987767 6.3692392 5.1531951 1.2054667 0.6019289 NKD2 −1.004673177 0.054532631 0.010680414 −54.49982243 6.9736463 6.3911446 7.9139132 4.3788962 1.2054667 0.6019289 GPKOW −0.918172687 0.063283514 0.015643906 −54.58971634 8.7700497 6.6706551 6.976024 5.5826351 1.2054667 0.6019289 OSBPL3 −1.20153285 0.049809046 0.005341411 −54.75154075 4.963444 7.1970971 6.861515 1.0866873 1.2054667 0.6019289 PXDC1 −1.287367142 0.04958755 0.004062425 −54.89880206 13.8357827 13.3895655 14.6550651 8.7677808 7.1932904 8.8763623 TAF1D −0.93106596 0.061288269 0.014662601 −55.12681398 10.324773 10.2084982 10.6313772 4.5400907 8.8624022 0.6019289 ARHGAP32 −1.497182857 0.04958755 0.002241033 −55.19414079 6.8731305 6.9314777 6.8006628 1.0866873 1.2054667 0.6019289 CCNC −1.017993933 0.053512074 0.010058573 −55.19414079 6.8731305 7.0089004 3.7641245 1.0866873 1.2054667 0.6019289 TRIP11 −0.839932745 0.079307362 0.024047982 −55.30030911 7.2983248 6.3911446 7.1809309 5.5826351 1.2054667 0.6019289 RAB24 −1.382539596 0.04958755 0.003155741 −55.3598023 7.1558353 6.8774542 6.0316576 1.0866873 1.2054667 0.6019289 PBX3 −1.266414594 0.04958755 0.004367327 −55.3598023 5.3354128 6.8774542 7.4222392 1.0866873 1.2054667 0.6019289 ORAOV1 −1.44175751 0.04958755 0.002722458 −55.84800011 6.8201191 7.0089004 6.4105447 1.0866873 1.2054667 0.6019289 C14orf169 −1.445476277 0.04958755 0.002698387 −56.04896295 7.463005 6.8496647 6.4105447 1.0866873 1.2054667 0.6019289 TMC5 −1.420661147 0.04958755 0.00287491 −56.33815629 6.4179694 7.1522986 6.564874 1.0866873 1.2054667 0.6019289 PLA2G2A −0.811796465 0.088696214 0.028875873 −56.4159582 1.8744435 6.9047187 7.7465254 1.0866873 1.2054667 0.6019289 KAT6A −1.181643125 0.049897122 0.005718527 −56.50543402 10.9699811 11.1831093 11.5706927 7.335969 5.3627916 0.6019289 UMPS −0.725297124 0.124297571 0.049588382 −56.67244581 6.6783891 7.0338116 7.0300422 6.6046733 1.2054667 0.6019289 AHCTF1 −1.444807895 0.04958755 0.002706411 −56.77802403 7.373845 6.4291897 6.8006628 1.0866873 1.2054667 0.6019289 GDAP2 −1.446555092 0.04958755 0.00268234 −56.8207099 6.6175557 7.0338116 6.564874 1.0866873 1.2054667 0.6019289 RACGAP1 −0.816099459 0.086958113 0.02805745 −56.8207099 6.6482929 7.0338116 8.2346552 6.32242 1.2054667 0.6019289 FBXO31 −0.80824163 0.089516458 0.029377357 −56.8207099 6.8989234 7.0338116 7.273415 6.0805901 1.2054667 0.6019289 SUFU −0.760523148 0.107869852 0.039803418 −57.25076191 7.0446897 6.8213295 8.0111355 6.8714329 1.2054667 0.6019289 CCL20 −0.969796366 0.057171148 0.012303619 −57.6309631 9.949176 8.8052757 6.4507011 6.3662802 1.2054667 0.6019289 NMUR1 −0.839507414 0.079317736 0.02411137 −57.71381923 7.0901803 6.7924268 7.0563116 5.6551006 1.2054667 0.6019289 MCC −1.456646958 0.04958755 0.002570007 −57.73125842 6.4532097 6.9047187 7.1323668 1.0866873 1.2054667 0.6019289 SLC1A3 −0.774466937 0.102109423 0.036434245 −57.73125842 6.4532097 8.4548593 9.0676963 1.0866873 7.8365643 0.6019289 RILPL1 −1.491652502 0.04958755 0.002305223 −57.79342406 6.7367617 7.0583001 6.8314096 1.0866873 1.2054667 0.6019289 CASK −1.416773443 0.04958755 0.002898981 −57.79342406 7.0901803 7.0583001 6.7371315 1.6938929 1.2054667 0.6019289 KIF21B −1.319295837 0.04958755 0.003725427 −57.79342406 5.6586086 7.0583001 6.976024 1.0866873 1.2054667 0.6019289 WRNIP1 −0.968662676 0.057313185 0.012411137 −57.79342406 6.8731305 7.0583001 7.4620859 4.8170878 1.2054667 0.6019289 TGFB1I1 −1.38402487 0.04958755 0.003147717 −58.07269421 13.445669 13.2916102 12.4468155 7.6868219 7.4318221 6.5688072 IQCE −1.274955253 0.04958755 0.004182781 −58.1436557 7.2389721 6.7020747 6.9482372 1.0866873 2.5373444 0.6019289 SHE −0.897868689 0.06669982 0.017333708 −58.16774841 7.0676142 6.6706551 7.2046135 5.1531951 1.2054667 0.6019289 GPT2 −1.37316698 0.04958755 0.003227955 −58.18110428 6.9491661 8.7234108 6.0316576 1.0866873 1.2054667 0.6019289 SEC31B −1.45215489 0.04958755 0.002610126 −58.25576141 6.8468682 6.4662577 7.6113033 1.0866873 1.2054667 0.6019289 PDDC1 −1.213226433 0.049622329 0.005161679 −58.25576141 6.9736463 6.4662577 7.481604 1.0866873 2.8554202 0.6019289 FAM50B −1.461235411 0.04958755 0.002521865 −58.52828813 6.9736463 6.9577495 6.4897707 1.0866873 1.2054667 0.6019289 MCM2 −1.447989742 0.04958755 0.002642221 −58.52828813 7.943836 6.9577495 6.4105447 1.0866873 1.2054667 0.6019289 MCRS1 −1.379018401 0.04958755 0.003171788 −58.52828813 8.2647067 6.9577495 6.0125266 1.0866873 1.2054667 0.6019289 CCT2 −1.376265498 0.04958755 0.003203883 −58.54185582 14.5375205 15.4536305 14.7443802 8.6661239 9.8496795 8.7884466 BMPR1A −0.75467612 0.110509614 0.041291021 −58.75519803 7.7448535 7.0089004 7.0821113 6.9310735 1.2054667 0.6019289 PSD −1.459126615 0.04958755 0.002545936 −59.1767676 6.9736463 6.4291897 7.4423001 1.0866873 1.2054667 0.6019289 WDR85 −1.250937065 0.04958755 0.00460804 −59.1767676 6.9736463 7.3033622 5.2252164 1.0866873 1.2054667 0.6019289 TMCO7 −1.453392299 0.04958755 0.002586055 −59.21299099 7.3921232 6.7924268 6.4897707 1.0866873 1.2054667 0.6019289 CHD7 −0.835488129 0.080837307 0.024786167 −59.21299099 7.1770729 7.3830764 6.4897707 5.7241063 1.2054667 0.6019289 POU6F1 −0.813669388 0.087770982 0.028457835 −59.79658195 8.0044995 6.8496647 7.1074578 6.4088472 1.2054667 0.6019289 POLE −0.748784251 0.11325619 0.042834791 −60.00173053 7.1123989 7.3237074 7.0032858 6.7770801 1.2054667 0.6019289 TKTL1 −1.270060388 0.04958755 0.004295114 −60.40510285 7.2389721 5.3406193 7.0032858 1.0866873 1.2054667 0.6019289 TIGD5 −1.458785999 0.04958755 0.00255396 −60.51751032 6.5212096 7.6317881 6.8314096 1.0866873 1.2054667 0.6019289 HPS6 −1.460325415 0.04958755 0.002537912 −60.79504453 8.2039211 6.9577495 6.5278107 1.0866873 1.2054667 0.6019289 AP1G2 −1.456046175 0.04958755 0.002578031 −60.79504453 6.7650859 7.4213407 6.5278107 1.0866873 1.2054667 0.6019289 MGRN1 −1.021505515 0.053385633 0.009920565 −60.79504453 8.2844125 7.6480149 6.5278107 4.8170878 1.2054667 0.6019289 DDR1 −0.84237993 0.078811783 0.023698147 −60.79504453 8.0512583 9.1453174 6.5278107 6.9599943 1.2054667 0.6019289 LOC100132077 −1.446697233 0.04958755 0.002666292 −61.21129731 6.7078705 6.537655 7.6635078 1.0866873 1.2054667 0.6019289 BTN2A2 −0.870170973 0.071776816 0.020322555 −61.21129731 7.8411348 6.537655 7.8848881 6.0269554 1.2054667 0.6019289 ATG2B −1.481823504 0.04958755 0.002401508 −61.53583637 7.4801945 6.537655 7.0300422 1.0866873 1.2054667 0.6019289 DDHD2 −0.784845532 0.098230159 0.034193212 −61.68432032 7.5951068 7.1522986 6.8910052 6.5294995 1.2054667 0.6019289 KCNH3 −1.395593779 0.04958755 0.003019337 −61.83572393 7.1558353 7.08238 6.0540376 1.0866873 1.2054667 0.6019289 ZCCHC14 −0.858047636 0.07443975 0.021522105 −61.83572393 7.1558353 6.9314777 8.3453359 6.2304884 1.2054667 0.6019289 C6orf228 −0.768128087 0.104791398 0.037960363 −61.87936411 6.6783891 7.3033622 7.1568531 6.4088472 1.2054667 0.6019289 PWWP2A −1.418967161 0.04958755 0.002890957 −62.16378112 7.0446897 6.1842483 7.2279137 1.0866873 1.2054667 0.6019289 ST7-AS1 −1.451955685 0.04958755 0.00261815 −62.37712183 7.5631978 6.7020747 6.564874 1.0866873 1.2054667 0.6019289 TREX1 −1.440363594 0.04958755 0.002730482 −62.37712183 8.4506083 6.7924268 6.564874 1.0866873 1.2054667 0.6019289 FBXL8 −1.436943373 0.04958755 0.002786648 −62.37712183 7.4971815 6.5720715 6.564874 1.0866873 1.2054667 0.6019289 WWC1 −0.834101668 0.081251647 0.024966701 −62.37712183 7.7305591 10.3491315 6.564874 7.3578678 1.2054667 0.6019289 DYRK2 −0.761661609 0.107291504 0.039519377 −62.68909303 7.2590288 6.5720715 7.7784397 6.7105675 1.2054667 0.6019289 IL23A −1.246891748 0.04958755 0.004656182 −62.92076189 7.0676142 5.1957839 7.1809309 1.0866873 1.2054667 0.6019289 SMURF1 −1.245079199 0.04958755 0.00467223 −63.75645085 13.205502 13.4922866 13.3951924 7.400693 8.6892694 0.6019289 CYP1A1 −1.468628309 0.04958755 0.00248977 −63.9592212 7.5139709 6.7924268 6.6010094 1.0866873 1.2054667 0.6019289 HTR7P1 −0.767367365 0.104951556 0.038139292 −63.9592212 7.6416849 7.2617905 6.6010094 6.6046733 1.2054667 0.6019289 IRX4 −1.264737812 0.04958755 0.004391399 −64.15514131 7.0901803 8.0287286 5.2252164 1.0866873 1.2054667 0.6019289 L0C100506835 −1.47233144 0.04958755 0.002465698 −64.16690561 6.8201191 6.6056864 7.5198657 1.0866873 1.2054667 0.6019289 G6PD −1.240306547 0.04958755 0.004712349 −64.20769258 13.5728075 12.9357477 12.3585146 6.9310735 1.2054667 8.4493889 SYT8 −0.877323097 0.070335652 0.019644548 −64.92807271 2.2016907 8.5442716 7.1074578 1.0866873 1.2054667 0.6019289 SPTLC2 −0.833721532 0.08138461 0.025047741 −65.00356981 7.5469748 6.9577495 7.2279137 6.1323043 1.2054667 0.6019289 CLK4 −0.792014303 0.095431107 0.03264543 −65.00356981 7.2590288 7.0338116 7.2279137 6.4088472 1.2054667 0.6019289 ATP6V1B1 −1.498372831 0.04958755 0.002216962 −65.54134109 7.0676142 7.77165 6.6362622 1.0866873 1.2054667 0.6019289 ZFP41 −1.485343071 0.04958755 0.002337318 −65.54134109 7.7305591 6.9314777 6.6362622 1.0866873 1.2054667 0.6019289 OPA1 −0.723957315 0.12484568 0.049991976 −65.54134109 8.0740814 7.5649923 6.6362622 7.4626381 1.2054667 0.6019289 GRK6 −1.402816972 0.04958755 0.003011313 −65.92160364 7.4279993 7.1293668 6.0560619 1.0866873 1.2054667 0.6019289 MARK3 −0.748829873 0.11325619 0.042818743 −66.04497956 7.2788106 7.1748717 7.2508437 6.9310735 1.2054667 0.6019289 MPDZ −0.781693536 0.099294769 0.034792586 −66.05882908 7.9313911 7.1293668 7.1323668 1.0866873 6.9073747 0.6019289 REC8 −1.001899297 0.054859251 0.010825644 −66.09017745 6.6482929 7.9126391 8.9323923 5.4258059 1.2054667 0.6019289 C10orf35 −1.061945922 0.051493437 0.008619915 −66.14651431 7.1342805 8.4174829 3.7641245 1.0866873 1.2054667 0.6019289 NUP205 −1.464959087 0.04958755 0.002513841 −66.42075071 7.2590288 7.1522986 6.4105447 1.0866873 1.2054667 0.6019289 SENP1 −1.472731922 0.04958755 0.002457675 −66.97780884 7.893399 7.1522986 6.4507011 1.0866873 1.2054667 0.6019289 TBC1D25 −0.846164576 0.077719653 0.023088341 −67.08639294 7.7448535 7.1060646 7.273415 6.2304884 1.2054667 0.6019289 DHCR7 −0.900805814 0.066271613 0.017069726 −67.12348009 8.7346746 8.3791124 6.6706745 6.4903918 1.2054667 0.6019289 ZFPM1 −1.497208629 0.04958755 0.00223301 −67.14220526 7.1558353 7.9653908 6.6010094 1.0866873 1.2054667 0.6019289 MUC1 −1.333349257 0.04958755 0.003589024 −67.14220526 7.1558353 9.3073441 5.7029118 1.0866873 1.2054667 0.6019289 PPP1R18 −1.264339428 0.04958755 0.004399422 −67.87854833 13.5314028 13.5873889 15.1530469 7.5025051 9.5024342 0.6019289 APOA1 −1.279466814 0.04958755 0.004126615 −68.03401776 5.3162271 7.1748717 7.5934735 1.0866873 1.2054667 0.6019289 TRIM29 −1.318614771 0.04958755 0.003733451 −68.13789901 7.1770729 9.3673812 5.5929159 1.0866873 1.2054667 0.6019289 PLCD1 −1.49212559 0.04958755 0.0022972 −68.25477669 7.2983248 6.8496647 6.7042855 1.0866873 1.2054667 0.6019289 BET1L −1.490769282 0.04958755 0.002321271 −68.60043399 8.0044995 6.7020747 6.9482372 1.0866873 1.2054667 0.6019289 IL1B −0.88488578 0.068629673 0.018704967 −68.60043399 9.0488124 6.7020747 10.5870107 7.7708426 1.2054667 0.6019289 PDK1 −0.817044141 0.086745168 0.027882532 −68.70563693 7.7161217 7.4213407 6.7042855 6.32242 1.2054667 0.6019289 C9orf91 −0.724351556 0.124712075 0.049856375 −69.16922996 7.8543794 7.3033622 7.3175252 7.6158948 1.2054667 0.6019289 GCLM −0.750048713 0.112640836 0.042419161 −69.17179262 7.3175786 7.4768994 7.1323668 7.0434341 1.2054667 0.6019289 TTC32 −1.511943235 0.04958755 0.002160796 −69.45112731 7.5305672 6.6385363 7.2046135 1.0866873 1.2054667 0.6019289 MCF2L −1.512578538 0.04958755 0.002152772 −70.0783039 8.1296079 6.7328249 7.1323668 1.0866873 1.2054667 0.6019289 GABARAPL1 −0.754590412 0.110509614 0.041299045 −70.0783039 7.4101728 6.7328249 8.1272196 7.147675 1.2054667 0.6019289 LBR −0.740086584 0.117838959 0.045312525 −70.0783039 7.6108005 6.7328249 7.5386226 7.0964955 1.2054667 0.6019289 BANP −0.847000038 0.077594277 0.022979218 −70.08881039 7.3365789 7.1293668 7.6635078 6.2304884 1.2054667 0.6019289 CHD8 −1.393122433 0.04958755 0.003051432 −70.14644612 7.4971815 7.2189854 5.9741452 1.0866873 1.2054667 0.6019289 LOC100133957 −0.769027696 0.1044167 0.037790259 −70.21065329 7.893399 7.0089004 7.3390847 7.0161533 1.2054667 0.6019289 SCAMP3 −0.799918713 0.092705411 0.031095242 −70.28781043 7.5139709 7.8154118 6.7371315 6.6046733 1.2054667 0.6019289 GCHFR −1.482189174 0.04958755 0.002385461 −70.58190233 7.4801945 6.4662577 7.2279137 1.0866873 1.2054667 0.6019289 SPEG −1.479590603 0.04958755 0.00242558 −70.58190233 6.5540448 8.6767186 7.2279137 1.0866873 1.2054667 0.6019289 BAIAP2L1 −1.154170686 0.04991757 0.006343577 −70.72720119 9.2068962 12.0654034 9.0805542 5.6551006 4.4251522 2.9363609 S100A3 −1.332050336 0.04958755 0.003597047 −71.12499591 7.2389721 8.3195726 5.5929159 1.0866873 1.2054667 0.6019289 TET2 −0.803877945 0.09087079 0.030150847 −71.12499591 7.2389721 7.0089004 8.3976469 1.0866873 6.9073747 0.6019289 PPP4C −1.130796382 0.050131358 0.006741555 −71.41178272 7.943836 7.3635569 7.273415 4.1976103 1.2054667 0.6019289 PPARG −1.007762246 0.054397005 0.01053037 −71.41178272 10.2590653 7.3635569 7.2279137 5.8529567 1.2054667 0.6019289 ANKS3 −0.79394253 0.094750565 0.032241033 −71.41178272 7.6416849 7.3635569 6.861515 6.5675757 1.2054667 0.6019289 ABLIM3 −0.89353122 0.067244392 0.017762978 −71.55618601 8.234634 6.7629335 7.5386226 5.9712523 1.2054667 0.6019289 DKC1 −1.496754126 0.04958755 0.002249057 −71.86999955 6.9491661 8.1476275 6.7692467 1.0866873 1.2054667 0.6019289 DPP3 −1.477407095 0.04958755 0.002441627 −72.2588875 8.1619262 7.2617905 6.4507011 1.0866873 1.2054667 0.6019289 SLC2A8 −0.790027729 0.095977935 0.032951135 −72.29350892 7.0676142 7.4586165 7.3812609 6.6408414 1.2054667 0.6019289 LOC158435 −0.927265603 0.061709548 0.014936211 −73.03407959 7.5951068 6.7924268 7.5754206 5.4258059 1.2054667 0.6019289 DFNB31 −1.534925226 0.04958755 0.002016368 −73.05625505 6.7928648 7.2617905 8.151795 1.0866873 1.2054667 0.6019289 PWWP2B −1.01121709 0.054161962 0.010346626 −73.3573053 6.8468682 7.4023354 7.8552671 4.8170878 1.2054667 0.6019289 WDR13 −0.841676272 0.078911195 0.023779989 −73.3573053 7.5469748 7.4023354 6.9199049 6.1323043 1.2054667 0.6019289 SHROOM1 −1.064598297 0.051378258 0.008515606 −73.45220328 8.1296079 7.8154118 6.8006628 4.6851838 1.2054667 0.6019289 ZNF668 −1.598622483 0.04958755 0.001697023 −74.1121141 7.2983248 7.1522986 7.4018955 1.0866873 1.2054667 0.6019289 CDH1 −1.481949348 0.04958755 0.002393485 −74.1121141 7.2983248 9.1047412 6.6010094 1.0866873 1.2054667 0.6019289 CRCP −1.328977546 0.04958755 0.003629142 −74.1121141 7.2983248 7.4213407 8.0245047 1.0866873 1.2054667 2.9363609 MVK −1.479685689 0.04958755 0.002417556 −74.37134082 8.2244688 7.3033622 6.4507011 1.0866873 1.2054667 0.6019289 ANKRD33B −0.757790562 0.109363019 0.040534382 −74.51198399 7.9561744 6.8213295 8.6685197 7.7544253 1.2054667 0.6019289 FBXL18 −1.019029046 0.053434625 0.010000802 −74.67392472 7.4279993 9.2711329 7.3390847 5.5826351 1.2054667 0.6019289 UCK2 −1.503785059 0.04958755 0.002192891 −75.03442075 6.9736463 8.309406 6.8314096 1.0866873 1.2054667 0.6019289 LOC440335 −1.446313563 0.04958755 0.002690363 −75.03442075 7.0676142 10.5175668 6.8314096 1.0866873 1.2054667 0.6019289 VTI1B −0.947296514 0.059309685 0.013491936 −75.03442075 8.1404613 7.6799309 6.8314096 5.5826351 1.2054667 0.6019289 SETDB1 −0.929131247 0.061465602 0.014779748 −75.03442075 7.9061745 7.5819833 6.8314096 5.5826351 1.2054667 0.6019289 SCGB3A1 −1.403479681 0.04958755 0.002995266 −75.10504189 6.5861495 12.0456339 7.3175252 1.0866873 1.2054667 0.6019289 SETD8 −1.338134765 0.04958755 0.003532857 −75.1923537 11.5698646 12.0224811 12.1348465 5.7899671 6.6483084 0.6019289 C1orf216 −0.792649967 0.09519921 0.032511434 −75.41781298 7.7161217 7.2617905 7.4423001 6.9015613 1.2054667 0.6019289 ELP3 −1.512987677 0.04958755 0.002144748 −75.42757164 7.6416849 7.3237074 6.6010094 1.0866873 1.2054667 0.6019289 RECK −0.784078996 0.098241201 0.034318382 −75.9898986 8.5996216 6.8496647 7.7625708 7.3578678 1.2054667 0.6019289 TMCO3 −0.787985178 0.096821537 0.033463853 −76.27560445 8.6984102 7.4586165 6.861515 7.1971015 1.2054667 0.6019289 PTPN6 −1.529250327 0.04958755 0.002072535 −76.4838051 6.7078705 7.3437697 8.1022182 1.0866873 1.2054667 0.6019289 AP1S1 −0.874595489 0.070910747 0.019886865 −76.61665111 8.9224556 7.7265191 6.861515 6.6046733 1.2054667 0.6019289 CREB5 −0.781181471 0.099549317 0.034914547 −76.61665111 8.2244688 7.5127845 6.861515 7.0702087 1.2054667 0.6019289 WDR5 −1.485089658 0.04958755 0.002345342 −77.09925115 7.3553323 7.4768994 6.4507011 1.0866873 1.2054667 0.6019289 LMBR1 −0.907892186 0.065167114 0.016538554 −77.24837461 7.373845 7.4768994 7.5571389 5.8529567 1.2054667 0.6019289 FUT4 −1.526606869 0.04958755 0.002096606 −77.36663297 7.5305672 6.6706551 7.3603269 1.0866873 1.2054667 0.6019289 RAB11FIP5 −1.564388351 0.04958755 0.001887988 −77.46782283 7.3553323 6.8774542 7.7465254 1.0866873 1.2054667 0.6019289 POM121 −1.619674349 0.04958755 0.001600738 −77.50069481 7.2788106 7.3237074 7.481604 1.0866873 1.2054667 0.6019289 MTERFD2 −0.850886516 0.076483673 0.022494584 −77.50069481 8.2745933 7.0583001 7.481604 6.5294995 1.2054667 0.6019289 PLEKHG4 −1.413178236 0.04958755 0.002915028 −77.54004108 7.8675036 7.3635569 6.0316576 1.0866873 1.2054667 0.6019289 CHCHD6 −0.875459502 0.070710498 0.01980743 −78.19889362 8.3038528 7.926009 6.8910052 6.4501951 1.2054667 0.6019289 FAM160B2 −0.846092007 0.077730608 0.023104389 −78.19889362 8.9287302 8.4079855 6.8910052 7.268205 1.2054667 0.6019289 ZBTB17 −0.756630664 0.109655369 0.040751023 −78.22114654 8.3699022 7.4949535 7.4620859 7.7544253 1.2054667 0.6019289 DCTN5 −0.941606189 0.060032865 0.013903555 −78.34204321 7.4971815 7.2617905 7.9840197 5.7241063 1.2054667 0.6019289 METTL1 −1.35841738 0.04958755 0.003364359 −78.59627948 7.6868062 7.3830764 5.7236017 1.0866873 1.2054667 0.6019289 GPIHBP1 −1.52816644 0.04958755 0.002080558 −78.94575618 7.6568826 6.9047187 6.9482372 1.0866873 1.2054667 0.6019289 LOC283663 −1.079098437 0.051291304 0.008157747 −78.94575618 7.8411348 6.9047187 8.5716641 4.8170878 1.2054667 0.6019289 ASB1 −0.76200063 0.107152042 0.039450373 −79.58358573 8.1512337 7.4586165 7.5198657 7.5976045 1.2054667 0.6019289 SLC4A3 −0.949358564 0.059079344 0.013311402 −80.02253901 6.9242634 8.9431715 7.8250252 6.0269554 1.2054667 0.6019289 PCBD2 −1.394115092 0.04958755 0.003043408 −80.086405 7.4101728 7.3033622 7.6972902 1.0866873 2.5373444 0.6019289 VARS2 −1.55714433 0.04958755 0.001920083 −80.17611035 7.5305672 7.0089004 7.0563116 1.0866873 1.2054667 0.6019289 KIAA1161 −0.784061636 0.098241201 0.034326406 −80.17611035 7.5305672 7.4586165 7.7138893 7.147675 1.2054667 0.6019289 LOC388692 −0.797962539 0.093669983 0.031619193 −80.42369814 7.6108005 6.9314777 7.8994736 6.8406623 1.2054667 0.6019289 TULP4 −0.877030927 0.070425023 0.01969269 −80.62503437 7.2983248 8.0654383 7.5386226 6.3662802 1.2054667 0.6019289 KIAA1530 −0.726840915 0.123667925 0.049156704 −80.70876318 7.463005 7.4213407 7.0821113 1.0866873 7.3469252 0.6019289 WDR44 −0.945566274 0.059597087 0.01362513 −81.09314574 7.5469748 7.5303978 8.2114624 5.9712523 1.2054667 0.6019289 DPH2 −1.580392082 0.04958755 0.001791703 −81.41581601 6.9491661 7.7265191 7.4018955 1.0866873 1.2054667 0.6019289 EPB41 −1.534209702 0.04958755 0.00204044 −81.41581601 6.9491661 7.8297091 6.976024 1.0866873 1.2054667 0.6019289 XPO5 −0.850734045 0.07656248 0.022543529 −81.88985198 8.8906661 8.731048 7.4423001 1.0866873 1.2054667 7.5859707 TRAF3 −0.748220565 0.11350837 0.043004894 −82.01018229 7.5631978 7.5819833 7.0300422 7.1971015 1.2054667 0.6019289 DUSP8 −0.764622734 0.106099876 0.038783599 −82.11225072 8.4242047 7.5649923 7.5386226 7.7870752 1.2054667 0.6019289 RGPD1 −1.603753769 0.04958755 0.001680976 −82.82125551 7.5305672 7.4586165 7.0821113 1.0866873 1.2054667 0.6019289 ECI1 −1.562951081 0.04958755 0.001896012 −82.82125551 8.234634 7.4586165 6.861515 1.0866873 1.2054667 0.6019289 HEBP2 −1.090137131 0.051027823 0.007811923 −82.94568721 8.5996216 8.1589958 6.976024 4.9379926 1.2054667 0.6019289 SLC5A6 −0.969653314 0.057171148 0.012319666 −82.94568721 9.1649884 9.5381761 6.976024 6.7770801 1.2054667 0.6019289 CYP4F30P −0.959501561 0.058066829 0.012834791 −83.0850306 7.2186326 7.5819833 7.9563845 5.5826351 1.2054667 0.6019289 ARHGEF40 −0.896457 0.066907118 0.017520661 −83.84425872 7.5951068 7.6153768 7.4423001 6.0805901 1.2054667 0.6019289 MECR −1.603389592 0.04958755 0.001688999 −84.76129852 7.6108005 7.3237074 7.1323668 1.0866873 1.2054667 0.6019289 HPDL −1.465928616 0.04958755 0.002505817 −86.06075619 7.5139709 7.9653908 6.2829045 1.0866873 1.2054667 0.6019289 GABRP −1.420407921 0.04958755 0.002882933 −86.4131138 6.4876101 11.6418829 7.5198657 1.0866873 1.2054667 0.6019289 ADCY2 −0.945201282 0.059597087 0.013665249 −86.59538116 7.6416849 7.2189854 8.4969013 5.9712523 1.2054667 0.6019289 KAT5 −0.978358618 0.056452334 0.011832625 −86.87376615 9.3725567 7.4768994 7.6463154 6.1822306 1.2054667 0.6019289 DGUOK −0.788873062 0.096395853 0.033221536 −86.97616394 9.625257 7.6480149 7.1323668 7.8958605 1.2054667 0.6019289 DISP1 −1.641610762 0.04958755 0.001488406 −87.05648639 7.5305672 7.6317881 7.273415 1.0866873 1.2054667 0.6019289 RAB35 −0.761371213 0.107520115 0.039621279 −87.91522748 8.062715 7.2617905 7.6635078 7.522033 1.2054667 0.6019289 CDH24 −1.584225542 0.04958755 0.001775656 −87.9489505 7.1770729 7.6640611 7.1074578 1.0866873 1.2054667 0.6019289 LRWD1 −1.121241482 0.050341156 0.006948568 −87.9489505 7.9561744 7.6640611 7.2046135 4.3788962 1.2054667 0.6019289 SH2B2 −1.054710393 0.051852306 0.008875873 −87.9489505 7.2788106 7.6640611 8.3020771 5.0495858 1.2054667 0.6019289 MAP3K6 −0.933178137 0.061078464 0.014515767 −88.38228495 7.0676142 8.2784691 9.0996286 6.5675757 1.2054667 0.6019289 HEATR7A −0.998030885 0.055362341 0.011018214 −88.42946762 7.671922 8.3888011 7.2279137 5.5063453 1.2054667 0.6019289 DTNBP1 −0.943387389 0.059848162 0.013793629 −88.42946762 7.671922 7.1522986 7.9563845 5.7241063 1.2054667 0.6019289 SP4 −0.776469077 0.101218075 0.035933563 −88.42946762 7.671922 7.1522986 8.3664885 7.4626381 1.2054667 0.6019289 SZT2 −0.763728008 0.10657523 0.039027521 −88.92173827 8.1296079 7.6799309 7.4423001 7.6517941 1.2054667 0.6019289 PYCRL −0.819098469 0.086243773 0.027636203 −88.95669037 7.2389721 7.8578854 7.6804979 6.8406623 1.2054667 0.6019289 C6orf136 −1.607515823 0.04958755 0.001656904 −89.29150746 7.7015384 7.08238 7.4620859 1.0866873 1.2054667 0.6019289 PMS2 −1.616417665 0.04958755 0.001624809 −89.34651221 7.6868062 7.3437697 7.2046135 1.0866873 1.2054667 0.6019289 LOC387646 −1.012391504 0.054044749 0.010274412 −89.34651221 7.6868062 7.1522986 7.9139132 5.1531951 1.2054667 0.6019289 ATXN2 −0.819126464 0.086237986 0.027620156 −89.89452721 7.5951068 7.6956281 8.1759589 7.221194 1.2054667 0.6019289 FAM105B −0.780864829 0.099749586 0.035001204 −89.99815478 7.786906 7.4213407 7.6972902 7.2911484 1.2054667 0.6019289 ZDHHC13 −1.161474288 0.04991757 0.006175078 −90.04368463 7.5792405 7.7265191 4.4498938 1.0866873 1.2054667 0.6019289 TUBBP5 −1.194741205 0.049809046 0.005445719 −90.26355767 7.7015384 8.3195726 7.5198657 4.1976103 1.2054667 0.6019289 SURF6 −0.986425466 0.056015811 0.011443473 −90.85719646 8.0965491 7.7111563 7.1074578 5.4258059 1.2054667 0.6019289 NIP7 −1.656555176 0.04958755 0.001408168 −90.86731728 7.4971815 7.7111563 7.3812609 1.0866873 1.2054667 0.6019289 FLJ31485 −1.335190989 0.04958755 0.003572976 −90.93641216 8.8113858 5.4876732 7.5934735 1.0866873 1.2054667 0.6019289 LOC401588 −1.427715926 0.04958755 0.002826767 −92.06724184 7.7730243 6.0604012 7.6113033 1.0866873 1.2054667 0.6019289 ZNF496 −1.129082857 0.050187311 0.006781674 −92.09765111 7.7305591 7.5127845 7.9976413 4.5400907 1.2054667 0.6019289 PAG1 −0.827229665 0.083495213 0.026170264 −92.24749547 10.322392 7.1293668 8.2231054 1.0866873 8.1688761 0.6019289 IL1RL1 −1.446586269 0.04958755 0.002674316 −92.43530004 12.1854726 12.5024742 11.7534205 5.6551006 6.1440192 0.6019289 FBRSL1 −0.810997289 0.088712957 0.028938458 −92.43952209 7.9061745 8.6608125 7.1323668 7.3794393 1.2054667 0.6019289 BIRC2 −1.012483014 0.054044749 0.010266389 −92.62053515 9.4356014 9.846632 9.3107812 7.5025051 2.9023413 0.6019289 TMEM165 −0.739323773 0.1180144 0.04557089 −92.81290068 8.7130255 7.7417201 7.6972902 8.4072489 1.2054667 0.6019289 FAM173A −1.631709047 0.04958755 0.001528524 −93.12255655 7.4801945 7.2189854 7.7465254 1.0866873 1.2054667 0.6019289 FZD5 −1.152147834 0.04991757 0.006367648 −93.31792243 8.518743 9.4804432 10.3553544 6.0269554 1.2054667 2.9363609 LCLAT1 −1.228448043 0.049622329 0.004937014 −94.02185473 9.9887526 7.8578854 7.1568531 4.1976103 1.2054667 0.6019289 GON4L −0.947912754 0.059309685 0.013443794 −94.02185473 8.7560036 8.225386 7.1568531 6.32242 1.2054667 0.6019289 ATRIP −0.856463294 0.074869193 0.02173634 −94.02185473 7.9061745 8.0410693 7.1568531 1.0866873 6.6948447 0.6019289 RHD −0.954938167 0.058459296 0.013038594 −94.16402651 8.2844125 7.6956281 7.7625708 6.1323043 1.2054667 0.6019289 GATS −1.437570115 0.04958755 0.002778625 −94.3289068 8.6074655 6.0924064 7.6463154 1.0866873 1.2054667 0.6019289 MKNK1 −0.921044084 0.062677445 0.015370296 −94.84879717 7.7730243 7.3635569 8.257481 6.2304884 1.2054667 0.6019289 TBC1D8 −1.543889611 0.04958755 0.001992297 −95.02237149 7.6568826 7.8717699 6.6706745 1.0866873 1.2054667 0.6019289 RIN3 −0.887065659 0.068365464 0.018446602 −95.20350534 7.893399 7.1748717 8.1022182 6.4088472 1.2054667 0.6019289 MAP1A −0.871861884 0.071556137 0.02016208 −95.20350534 8.0044995 7.1748717 9.232296 7.1223122 1.2054667 0.6019289 STX1A −1.070095654 0.051378258 0.00836476 −95.34887174 7.1770729 8.5869821 8.4281467 5.3405168 1.2054667 0.6019289 HES6 −1.57850311 0.04958755 0.001799727 −95.45974195 8.0044995 6.8496647 7.6635078 1.0866873 1.2054667 0.6019289 KRT80 −1.57494503 0.04958755 0.001823798 −95.45974195 6.9736463 9.1395902 7.6635078 1.0866873 1.2054667 0.6019289 CSNK2A1P −1.076350836 0.051291304 0.008189842 −95.83078903 11.2635145 11.4779465 10.9944785 8.7093547 1.2054667 4.6810971 ZNF33A −1.597132956 0.04958755 0.001705047 −96.01811201 7.671922 8.0774702 6.9482372 1.0866873 1.2054667 0.6019289 MIR3682 −1.571922698 0.04958755 0.00184787 −96.55262725 6.8201191 7.6799309 8.2799514 1.0866873 1.2054667 0.6019289 SV2A −1.501682231 0.04958755 0.002200915 −96.55262725 9.6894845 7.6799309 6.6010094 1.0866873 1.2054667 0.6019289 ZNF512 −1.609270458 0.04958755 0.001648881 −96.5905788 7.9805393 7.0089004 7.6804979 1.0866873 1.2054667 0.6019289 GPR133 −1.448796509 0.04958755 0.002634197 −96.5905788 8.3325307 6.1390574 7.6804979 1.0866873 1.2054667 0.6019289 HRAS −0.800975915 0.09207197 0.030776699 −97.18653973 8.5434862 8.3396934 7.2046135 7.704022 1.2054667 0.6019289 HPCAL1 −0.774515452 0.102109423 0.036410976 −97.18653973 8.3882311 9.0869958 7.2046135 1.0866873 8.3250145 0.6019289 CRABP1 −1.148146775 0.049952273 0.006438257 −97.72141729 4.2098819 8.5002579 7.6972902 1.0866873 1.2054667 0.6019289 SLC7A8 −0.74755663 0.11383441 0.043168579 −98.15953515 9.3725567 7.2189854 8.6685197 8.8855392 1.2054667 0.6019289 SLC9B2 −0.861646901 0.073515148 0.021028645 −98.64967465 8.5020086 7.8297091 7.7625708 7.147675 1.2054667 0.6019289 FOXC2 −1.490800072 0.04958755 0.002313247 −98.66516766 8.0044995 7.7111563 6.3692392 1.0866873 1.2054667 0.6019289 AVPI1 −1.642058323 0.04958755 0.001480382 −99.0053393 7.7161217 7.1748717 8.0377511 1.0866873 1.2054667 0.6019289 LOC100506730 −0.894587493 0.067185728 0.017681136 −99.04249435 8.4418607 7.8991443 8.3238686 1.6938929 6.9843361 0.6019289 MXD3 −1.237265891 0.04958755 0.004768515 −99.43405496 7.8411348 8.101237 7.2508437 3.7493131 1.2054667 0.6019289 MIIP −0.877983737 0.070255881 0.019563508 −99.43405496 7.8411348 7.843866 7.6463154 6.6046733 1.2054667 0.6019289 C11orf91 −1.018032408 0.053512074 0.01005055 −99.52887028 7.2389721 8.9166266 8.9743323 6.1822306 1.2054667 0.6019289 ALDH9A1 −0.911140092 0.06461959 0.016240071 −99.63755699 8.9779688 7.2405467 7.8552671 6.6046733 1.2054667 0.6019289 RECQL4 −1.565773327 0.04958755 0.001879965 −99.72143967 6.7928648 7.7265191 8.5533334 1.0866873 1.2054667 0.6019289 TERF2 −0.896274379 0.066907118 0.017536709 −100.3511085 7.8543794 7.6153768 8.0377511 6.5294995 1.2054667 0.6019289 ST3GAL5 −0.803526046 0.090941756 0.030189361 −100.9222099 7.2590288 7.8991443 7.9563845 7.1725999 1.2054667 0.6019289 DBN1 −0.738852144 0.118078127 0.045719329 −101.1155832 9.4487599 7.2617905 8.2461133 8.8081111 1.2054667 0.6019289 TBCC −1.223850645 0.049622329 0.00499318 −101.5680736 9.2823359 7.8717699 7.8096632 4.5400907 1.2054667 0.6019289 WDR34 −1.529456393 0.04958755 0.002056487 −101.8339871 8.0512583 7.7567626 6.564874 1.0866873 1.2054667 0.6019289 MEN1 −1.624573861 0.04958755 0.001576667 −102.2447866 8.6984102 7.1293668 7.7625708 1.0866873 1.2054667 0.6019289 DKFZp761E198 −0.928406191 0.06157485 0.014826286 −102.7263479 10.9881205 9.6309041 9.4609238 8.5086224 2.9023413 2.7782613 SELRC1 −1.700155281 0.04958755 0.001223622 −103.5136769 7.7590076 7.8991443 7.5008617 1.0866873 1.2054667 0.6019289 BTBD10 −0.893691618 0.067225527 0.017738907 −103.5136769 8.0044995 7.8991443 7.6972902 6.6046733 1.2054667 0.6019289 IDH3A −1.651366521 0.04958755 0.001448287 −103.5159803 7.9805393 7.5649923 7.2956386 1.0866873 1.2054667 0.6019289 IARS −0.892554622 0.067505375 0.01789858 −103.5159803 8.518743 8.1129752 7.2956386 6.7442069 1.2054667 0.6019289 NEDD9 −0.75098096 0.112223511 0.042208136 −103.5159803 8.559749 9.9647026 7.2956386 1.0866873 9.1731002 0.6019289 N4BP1 −1.581234598 0.04958755 0.00178368 −103.9465389 8.1935364 7.7863852 6.8314096 1.0866873 1.2054667 0.6019289 LDLRAP1 −1.439187606 0.04958755 0.002762577 −103.9840689 7.786906 8.2991672 6.0560619 1.0866873 1.2054667 0.6019289 CFP −0.863006793 0.073206726 0.020904277 −104.0193286 7.9061745 7.3437697 7.9840197 6.6761254 1.2054667 0.6019289 ABLIM2 −1.66185065 0.04958755 0.001376073 −104.0716479 8.4593032 7.3033622 7.7625708 1.0866873 1.2054667 0.6019289 CX3CL1 −1.136606456 0.050038461 0.006638851 −105.0983536 8.3038528 9.1047412 7.3175252 5.0495858 1.2054667 0.6019289 LOC152217 −0.804666039 0.090664228 0.029992779 −105.4592832 7.9925691 7.926009 7.7138893 7.4626381 1.2054667 0.6019289 SERINC2 −1.431606119 0.04958755 0.002802696 −105.9755664 7.8142752 9.2500252 6.0316576 1.0866873 1.2054667 0.6019289 ZFYVE1 −1.042998888 0.052218844 0.009225708 −106.4320874 7.8142752 7.939256 9.1308694 5.9133149 1.2054667 0.6019289 TMOD1 −0.985105936 0.056096089 0.011522105 −106.6807318 9.5741372 8.3296681 7.3390847 6.4903918 1.2054667 0.6019289 BRAT1 −0.885930455 0.068486123 0.018589425 −106.6807318 8.8581604 7.9523826 7.3390847 6.9015613 1.2054667 0.6019289 PGAM5 −0.772531831 0.102996779 0.036937335 −106.7704996 7.943836 8.2574696 7.4018955 7.7544253 1.2054667 0.6019289 ABCD1 −0.944800461 0.059600929 0.013705368 −107.027728 8.2745933 7.3437697 8.7512612 6.4903918 1.2054667 0.6019289 TMEM63A −1.628461023 0.04958755 0.001552596 −107.1153742 8.4152951 7.8297091 7.0821113 1.0866873 1.2054667 0.6019289 MTAP −1.403361023 0.04958755 0.00300329 −107.1153742 7.8543794 7.8297091 7.5754206 1.0866873 2.8554202 0.6019289 PRRG1 −0.936403251 0.060682102 0.014251785 −107.4048923 8.559749 7.9523826 7.7784397 6.5675757 1.2054667 0.6019289 CENPO −0.911417367 0.064529265 0.016185509 −107.4048923 8.4152951 7.9523826 7.4423001 6.5294995 1.2054667 0.6019289 MICU1 −0.904709839 0.065548582 0.016764824 −107.7032389 8.4418607 7.5649923 7.9563845 6.6761254 1.2054667 0.6019289 FLT4 −0.77762629 0.100926453 0.035721736 −107.8889534 7.3553323 8.0410693 9.6058253 1.0866873 8.4387969 0.6019289 ZFAND2B −0.818764938 0.086352882 0.027699591 −108.1716545 8.5020086 7.843866 8.2910567 1.0866873 1.2054667 7.7187266 TRIP4 −1.066136222 0.051378258 0.00845944 −108.2631145 9.2068962 8.2784691 7.3603269 5.6551006 1.2054667 0.6019289 PARN −0.840559145 0.079141153 0.023916393 −108.3776979 9.545842 7.9653908 7.4222392 7.704022 1.2054667 0.6019289 ADRB3 −1.692806226 0.04958755 0.001263741 −109.0298814 7.9061745 7.4213407 7.8552671 1.0866873 1.2054667 0.6019289 SLC4A2 −0.803232363 0.091042429 0.030244724 −109.0298814 8.8382996 7.843866 7.8552671 1.0866873 7.9937674 0.6019289 MIB2 −0.937045989 0.060673 0.01421969 −109.3505041 7.5951068 7.9782827 8.050877 6.2304884 1.2054667 0.6019289 GET4 −0.851348292 0.076222506 0.022392682 −109.7862091 7.6108005 8.4079855 7.9840197 7.1971015 1.2054667 0.6019289 THRAP3 −0.765566314 0.105690271 0.038546899 −109.7862091 8.7560036 7.926009 7.9840197 8.4281014 1.2054667 0.6019289 TMEM53 −0.94368197 0.059774383 0.013763139 −109.8119015 9.3162351 9.3276354 8.9674264 7.7708426 2.5373444 0.6019289 TM4SF18 −1.686526041 0.04958755 0.001295836 −109.8455017 8.2039211 7.8297091 7.3812609 1.0866873 1.2054667 0.6019289 CCDC167 −0.982586278 0.05631807 0.011680173 −109.8455017 8.5838045 7.9910605 7.3812609 5.9712523 1.2054667 0.6019289 SRCAP −1.652071958 0.04958755 0.001440263 −109.9838222 7.5139709 7.3830764 8.313014 1.0866873 1.2054667 0.6019289 TLE4 −0.873886546 0.071004424 0.019959881 −110.323311 7.5139709 7.9910605 8.8671038 7.147675 1.2054667 0.6019289 ADCK5 −1.68060118 0.04958755 0.001311883 −111.4618743 8.5104001 7.4023354 7.7941359 1.0866873 1.2054667 0.6019289 CSPP1 −1.501080745 0.04958755 0.002208938 −111.8691825 6.3818471 7.9523826 8.0111355 1.0866873 1.2054667 0.6019289 CNTFR −1.633825233 0.04958755 0.001520501 −111.9500755 7.893399 7.08238 8.3346422 1.0866873 1.2054667 0.6019289 UNC50 −0.821592775 0.085414368 0.027145952 −112.4224448 8.7130255 7.6956281 7.8994736 1.0866873 7.6833888 0.6019289 CUL9 −1.648265224 0.04958755 0.001456311 −112.9399295 7.4971815 7.4213407 8.5253933 1.0866873 1.2054667 0.6019289 FBXW2 −0.925072897 0.061862376 0.015060579 −113.0102885 9.1218267 8.5953745 7.4222392 7.0434341 1.2054667 0.6019289 CREB1 −0.8179622 0.086474917 0.027781433 −113.4530692 7.8411348 7.9126391 8.5897647 1.0866873 7.7510357 0.6019289 CITED4 −1.549867771 0.04958755 0.00197625 −113.9415836 7.9188379 9.4576082 6.7371315 1.0866873 1.2054667 0.6019289 ITGA10 −1.688102437 0.04958755 0.001279788 −114.4179877 7.7448535 7.440099 8.2799514 1.0866873 1.2054667 0.6019289 CCDC71 −1.494359426 0.04958755 0.002273128 −114.5926879 8.6384218 8.3195726 7.4423001 2.6271932 1.2054667 0.6019289 GFM1 −0.900747633 0.066280364 0.017085774 −114.5926879 8.8449503 8.9166266 7.4423001 7.3137327 1.2054667 0.6019289 USP54 −0.898399296 0.066677304 0.017283961 −114.5926879 8.3134756 8.1702751 7.4423001 6.7105675 1.2054667 0.6019289 TNK2 −0.968614125 0.057313185 0.012419161 −114.8557622 7.4456083 8.8827436 8.5347669 6.5294995 1.2054667 0.6019289 RAD21 −0.863633724 0.073142123 0.020849715 −115.0240391 8.0512583 8.0654383 8.0245047 7.1725999 1.2054667 0.6019289 CLK3 −0.934301045 0.060990824 0.014430715 −115.1873542 7.9188379 8.0533052 8.3976469 6.6408414 1.2054667 0.6019289 ZNF195 −0.833328386 0.081558088 0.025127979 −115.1873542 8.0965491 8.0533052 7.6463154 7.268205 1.2054667 0.6019289 ITPK1 −0.878801921 0.069923269 0.019379764 −115.9411012 8.062715 8.214531 8.0377511 7.1223122 1.2054667 0.6019289 ZC3H18 −0.96572928 0.057385588 0.012533098 −116.0351384 8.1830764 7.7567626 8.0638846 6.1822306 1.2054667 0.6019289 S100A7 −1.697906723 0.04958755 0.001239669 −116.1750909 7.9188379 8.6846063 7.4620859 1.0866873 1.2054667 0.6019289 KRT7 −0.910265331 0.064737869 0.016344379 −116.1750909 8.7418194 11.8243128 7.4620859 1.0866873 8.3687411 0.6019289 UBE2Q1 −0.82138717 0.085414368 0.027179652 −116.1750909 8.9960085 8.7760413 7.4620859 8.1174489 1.2054667 0.6019289 LYN −1.681654987 0.04958755 0.001303859 −116.2491308 7.463005 8.9099134 7.8402254 1.0866873 1.2054667 0.6019289 KIAA1549 −0.934478843 0.060960411 0.014407446 −116.9458772 7.5792405 8.2991672 7.9563845 1.0866873 6.3900594 0.6019289 RUSC1 −0.945182934 0.059597087 0.013673273 −117.3741127 8.4850778 7.4768994 8.2799514 6.4501951 1.2054667 0.6019289 XIRP1 −1.381740013 0.04958755 0.003163765 −117.6782154 5.6586086 7.9653908 8.9037393 1.0866873 1.2054667 0.6019289 KIFC3 −0.968105352 0.057313185 0.012435208 −117.7574976 8.7839604 9.5468566 7.481604 6.9599943 1.2054667 0.6019289 PROSER1 −1.673022607 0.04958755 0.001343978 −117.7752267 8.085359 8.0654383 7.2508437 1.0866873 1.2054667 0.6019289 DNHD1 −1.066843604 0.051378258 0.008435369 −118.1181206 8.7839604 7.6640611 8.0895532 5.5826351 1.2054667 0.6019289 CYHR1 −0.904079679 0.065667985 0.016816978 −118.1181206 8.4330597 7.6153768 8.0895532 6.7770801 1.2054667 0.6019289 SLC25A43 −1.714560415 0.04958755 0.001159432 −118.69229 8.0965491 7.926009 7.5008617 1.0866873 1.2054667 0.6019289 NUP214 −0.773763104 0.102561162 0.036646072 −119.1596127 8.2844125 7.8578854 8.1022182 8.1174489 1.2054667 0.6019289 TBP −1.710400436 0.04958755 0.001191527 −119.7907928 8.4418607 7.9910605 7.4620859 1.0866873 1.2054667 0.6019289 MATL2963 −1.452171834 0.04958755 0.002602102 −119.7907928 7.8142752 7.9910605 8.1022182 1.0866873 2.8554202 0.6019289 SSFA2 −0.948970074 0.059206517 0.013359544 −120.051411 7.893399 8.1129752 8.4775892 6.5675757 1.2054667 0.6019289 MAP3K4 −1.711613147 0.04958755 0.001175479 −120.3384614 8.1725401 7.4586165 7.9976413 1.0866873 1.2054667 0.6019289 PDCD11 −1.717677633 0.04958755 0.001151408 −120.9223211 7.9561744 8.464054 7.5198657 1.0866873 1.2054667 0.6019289 LY6K −1.033216317 0.052897282 0.009569927 −120.9223211 8.3699022 9.7708544 7.5198657 6.2771857 1.2054667 0.6019289 RHOD −0.949075258 0.059206517 0.013351521 −120.9223211 8.5270379 10.2275206 7.5198657 7.2911484 1.2054667 0.6019289 YRDC −0.909435869 0.064939231 0.016416593 −121.0242239 8.5352855 8.1246187 7.7465254 6.8714329 1.2054667 0.6019289 BEGAIN −0.970096616 0.057171148 0.0122635 −121.8226255 7.5305672 9.0988503 9.0350412 6.9015613 1.2054667 0.6019289 SEC23A −0.769334871 0.104294685 0.037660274 −121.9970372 11.082598 8.136169 7.9563845 9.6016369 1.2054667 0.6019289 DPYSL4 −1.714051698 0.04958755 0.001167456 −122.2840926 7.4456083 8.136169 8.1395596 1.0866873 1.2054667 0.6019289 ELF4 −1.781203872 0.04958755 0.000942791 −122.6001885 8.0280683 7.9126391 8.0245047 1.0866873 1.2054667 0.6019289 USP4 −1.753437705 0.04958755 0.001039076 −122.9596638 8.0740814 8.0287286 7.6972902 1.0866873 1.2054667 0.6019289 NSMCE1 −1.603874523 0.04958755 0.001672952 −122.9596638 8.2941654 8.0287286 6.8910052 1.0866873 1.2054667 0.6019289 SAP25 −1.020514947 0.053420513 0.00995266 −122.969851 7.9684083 8.1476275 9.9450759 6.6046733 1.2054667 0.6019289 RIC8B −1.637264245 0.04958755 0.001504453 −123.5413253 7.9061745 7.5819833 8.6427428 1.6938929 1.2054667 0.6019289 CASP9 −0.918951128 0.063218173 0.015586135 −124.0159555 7.6868062 8.0410693 8.7104835 1.0866873 6.8260777 0.6019289 TEKT4 −0.970642644 0.057154457 0.012247452 −124.0871574 9.1596632 9.0137478 7.5571389 6.9310735 1.2054667 0.6019289 PDE6A −1.777079975 0.04958755 0.000958838 −124.3670823 8.0044995 7.843866 8.1639276 1.0866873 1.2054667 0.6019289 C6orf1 −0.845486138 0.077930488 0.023202279 −124.9154799 8.7908658 8.1702751 7.5754206 7.522033 1.2054667 0.6019289 UBA1 −0.774500595 0.102109423 0.036419 −124.9154799 9.031425 8.1702751 7.9282096 8.5848861 1.2054667 0.6019289 ANAPC7 −0.836934433 0.080350378 0.024583969 −125.0722477 8.1404613 8.0533052 7.5754206 1.0866873 7.2567201 0.6019289 TRIM11 −0.906514543 0.065320795 0.016634037 −125.4085779 8.2142315 7.9910605 8.1759589 6.9015613 1.2054667 0.6019289 PAK1 −1.738444973 0.04958755 0.001063147 −125.888295 7.6568826 8.181467 7.8848881 1.0866873 1.2054667 0.6019289 COX18 −1.693540988 0.04958755 0.001255717 −125.8906781 8.062715 7.3437697 8.3238686 1.0866873 1.2054667 0.6019289 MEG3 −0.968059287 0.057313185 0.012443232 −125.9806114 11.3183106 12.7395811 13.6991642 11.2973689 5.7625232 0.6019289 CHRD −0.840425429 0.079172346 0.02396293 −126.0288094 8.1830764 7.8154118 8.355951 7.5025051 1.2054667 0.6019289 DGKA −1.02915944 0.053066061 0.009703924 −126.8611105 7.786906 8.1925727 8.4281467 5.8529567 1.2054667 0.6019289 ASMTL-AS1 −1.3265779 0.04958755 0.003661237 −127.1848339 5.3162271 8.0774702 8.4281467 1.0866873 1.2054667 0.6019289 HLA-DRB1 −0.907934297 0.065167114 0.01653053 −127.1848339 8.4418607 8.0774702 2.1654208 1.0866873 1.2054667 0.6019289 SEMA3B −1.293203471 0.04958755 0.003990211 −127.3961494 7.5951068 11.1292182 10.2653112 5.4258059 1.2054667 0.6019289 UBASH3B −1.166914886 0.04991757 0.006070769 −127.3961494 7.5951068 9.8744841 10.6291909 6.1822306 1.2054667 0.6019289 MAP7D1 −1.276723003 0.04958755 0.00415871 −127.7785741 13.436616 14.1921646 13.6349676 9.5924293 1.2054667 6.6374655 SYT15 −1.018883332 0.053434625 0.01001685 −127.8629426 8.2039211 8.181467 8.5987306 6.2304884 1.2054667 0.6019289 RINT1 −1.081430833 0.051255379 0.008075905 −128.8067428 8.9349778 8.214531 7.7784397 5.6551006 1.2054667 0.6019289 RARG −1.707528008 0.04958755 0.001215598 −129.3853887 7.4101728 8.4912918 8.1022182 1.0866873 1.2054667 0.6019289 NUDCD3 −0.811280509 0.088696214 0.02889192 −129.3853887 9.4443871 8.0162816 8.1022182 1.0866873 8.4524089 0.6019289 GGA2 −0.961568439 0.05775016 0.012688759 −129.6970769 8.2244688 7.6640611 8.6164969 6.4501951 1.2054667 0.6019289 BOP1 −0.841008568 0.079024571 0.023840167 −129.8737246 8.1076531 9.3916776 8.6340471 1.0866873 1.2054667 8.2877844 MCOLN2 −1.082842865 0.051255379 0.008051833 −130.6141445 8.234634 7.885522 9.9798073 6.0805901 1.2054667 0.6019289 KLHL36 −0.886923443 0.068365464 0.018477092 −130.6160642 7.8675036 8.4174829 8.2346552 7.147675 1.2054667 0.6019289 TMEM115 −0.84830834 0.077303306 0.022862874 −130.7523766 8.5838045 8.23616 8.076776 7.7210195 1.2054667 0.6019289 RNF216 −0.818882516 0.086352882 0.027691567 −130.7523766 8.4242047 8.23616 7.8552671 7.8031272 1.2054667 0.6019289 C9orf41 −1.737871523 0.04958755 0.001079194 −131.5763092 7.6416849 8.0162816 8.7187318 1.0866873 1.2054667 0.6019289 EDN1 −1.547333597 0.04958755 0.001984273 −131.8652503 8.1296079 9.212327 6.6010094 1.0866873 1.2054667 0.6019289 CASKIN1 −0.80252372 0.091248678 0.030396373 −132.6980119 8.9473922 8.2574696 7.6972902 8.1554584 1.2054667 0.6019289 NBEAL2 −1.178789266 0.049897122 0.005838883 −132.9696988 7.6568826 8.7980224 9.0547229 5.1531951 1.2054667 0.6019289 USP31 −0.945273203 0.059597087 0.013649202 −133.365349 8.2647067 9.5029224 7.9139132 7.147675 1.2054667 0.6019289 PRDM2 −0.814438287 0.08753544 0.028323839 −133.365349 8.2647067 7.7417201 8.313014 7.7378191 1.2054667 0.6019289 CLN6 −1.730463411 0.04958755 0.001103266 −133.5817338 7.9061745 8.6924512 7.6635078 1.0866873 1.2054667 0.6019289 ARFIP2 −0.998090167 0.0553384 0.011002166 −133.5817338 9.1808468 8.3693581 7.6635078 6.4501951 1.2054667 0.6019289 ATAD3A −0.851977218 0.076025266 0.0222972 −133.5817338 8.3134756 8.5355756 7.6635078 7.4626381 1.2054667 0.6019289 SENP5 −1.808464908 0.04958755 0.000862553 −133.7405618 8.1404613 7.9653908 8.26876 1.0866873 1.2054667 0.6019289 SNORD22 −0.977607843 0.056452334 0.011856696 −133.7405618 8.0512583 8.8895842 8.26876 6.6761254 1.2054667 0.6019289 RHOG −0.79945818 0.092882057 0.031200353 −134.6436487 8.6836453 8.2784691 8.0111355 8.2521782 1.2054667 0.6019289 ZBTB5 −1.709658146 0.04958755 0.001207574 −135.0397414 8.3325307 7.4023354 8.1639276 1.0866873 1.2054667 0.6019289 WDR77 −0.892391203 0.067567176 0.01793228 −135.1994867 8.2844125 9.4060615 7.9423658 7.6339561 1.2054667 0.6019289 RUFY1 −1.072668419 0.051291304 0.008278103 −135.6164675 8.5352855 8.2888552 7.8848881 5.6551006 1.2054667 0.6019289 DHX37 −1.058119957 0.051725293 0.008786007 −136.1165559 8.2941654 8.9884813 7.8994736 5.9712523 1.2054667 0.6019289 ZDHHC14 −1.230390684 0.04958755 0.004888871 −136.2910611 9.4487599 9.8218125 9.6278916 6.0269554 2.5373444 0.6019289 LCP1 −0.882681535 0.069240191 0.018962529 −136.589157 9.3018043 7.6956281 9.4756 8.1428995 1.2054667 0.6019289 APRT −1.059727634 0.051660967 0.008698548 −136.7466126 9.4960062 9.6062 7.6972902 6.6408414 1.2054667 0.6019289 PIAS3 −1.168916415 0.04991757 0.006006579 −136.8650636 9.2921029 8.2574696 8.3020771 5.4258059 1.2054667 0.6019289 C1orf27 −0.810423663 0.088976142 0.029082885 −137.0336254 8.3038528 8.3693581 8.1022182 8.0382872 1.2054667 0.6019289 GNL2 −0.837940573 0.07993439 0.024377758 −137.3014868 7.7305591 9.2393544 8.1878908 1.0866873 7.956043 0.6019289 ABCF3 −0.885182575 0.068624233 0.018672872 −137.5621063 8.3882311 8.309406 8.2910567 7.4216382 1.2054667 0.6019289 LTBP2 −1.055657991 0.051814299 0.008851801 −138.5432709 7.7161217 9.9582098 8.7830733 6.4903918 1.2054667 0.6019289 NIN −0.858288265 0.07443975 0.02149001 −139.7848352 8.3325307 8.2035936 9.3590709 8.1302303 1.2054667 0.6019289 EIF4E2 −1.092219531 0.050952718 0.007749338 −139.9115003 9.7078433 8.5180248 7.7302997 5.9712523 1.2054667 0.6019289 GFPT1 −1.00333721 0.054590844 0.010727754 −139.9895691 9.6097199 8.0894025 8.3346422 6.8092213 1.2054667 0.6019289 EIF5B −0.896694096 0.066891468 0.01749659 −140.7019057 8.3419647 8.715733 8.076776 7.3794393 1.2054667 0.6019289 BCAN −0.932558572 0.06110322 0.014547862 −141.0234444 8.6836453 7.7417201 8.8596637 7.0964955 1.2054667 0.6019289 DCLRE1C −1.041626265 0.052218844 0.009265827 −141.0310718 8.6307448 7.885522 8.3453359 5.9712523 1.2054667 0.6019289 TAB3 −0.991773349 0.055676176 0.011206772 −142.5015434 8.5270379 7.7567626 8.6513864 6.4088472 1.2054667 0.6019289 ACOX3 −1.769947548 0.04958755 0.000990933 −143.1140782 7.8675036 7.8991443 8.3664885 1.0866873 1.2054667 0.6019289 RNF123 −0.839677133 0.079317736 0.024103346 −144.0867366 9.545842 8.738645 8.257481 1.0866873 1.2054667 8.5238744 ACCN3 −1.122190853 0.050341156 0.006924497 −146.317496 7.9805393 8.3984252 9.0350412 5.5826351 1.2054667 0.6019289 ENDOG −0.858546474 0.07443975 0.021457915 −146.3484907 9.0488124 9.0074725 8.2799514 1.0866873 1.2054667 8.2443879 RASA4P −0.866514478 0.0723611 0.02059135 −146.9358494 8.720278 7.8009715 9.708794 8.180253 1.2054667 0.6019289 UPF3B −0.93047712 0.061334604 0.014717965 −147.1214047 8.40633 8.5442716 8.2231054 7.0964955 1.2054667 0.6019289 PHRF1 −0.923044751 0.062250826 0.015204204 −147.1214047 8.40633 8.5180248 7.9282096 6.988347 1.2054667 0.6019289 TRIM3 −1.11520298 0.050341156 0.007117067 −147.2800955 8.5516405 8.101237 8.4078853 5.5063453 1.2054667 0.6019289 HEATR1 −1.770087533 0.04958755 0.000982909 −149.4062111 8.085359 8.8963925 7.8250252 1.0866873 1.2054667 0.6019289 C9orf142 −1.268615334 0.04958755 0.004327209 −149.4062111 8.5678121 8.6527933 7.8250252 4.3788962 1.2054667 0.6019289 CARHSP1 −1.797501719 0.04958755 0.000910696 −151.0838776 7.8411348 8.4456055 8.2346552 1.0866873 1.2054667 0.6019289 UBL4A −1.361078988 0.04958755 0.003332263 −151.1816109 9.7509741 8.4456055 8.4281467 4.3788962 1.2054667 0.6019289 GLRX −0.828147293 0.083137747 0.025984113 −151.4461182 8.4593032 8.3595375 8.4481275 8.1302303 1.2054667 0.6019289 TPP1 −0.930932127 0.061288269 0.014670625 −151.7067672 8.4506083 8.2574696 8.9109561 7.3137327 1.2054667 0.6019289 TCHP −1.84525382 0.04958755 0.000742197 −152.1544347 8.085359 8.4548593 8.3238686 1.0866873 1.2054667 0.6019289 PSMG4 −1.807936788 0.04958755 0.000878601 −152.4876246 7.8675036 8.3296681 8.458015 1.0866873 1.2054667 0.6019289 FNDC4 −0.860854484 0.073757739 0.021146594 −153.1272587 9.031425 8.464054 8.1639276 7.9970157 1.2054667 0.6019289 LOC729603 −0.843530888 0.0786267 0.02357779 −153.5291314 9.2171857 8.4174829 8.4678353 1.0866873 1.2054667 8.2662493 MRPS35 −1.447757306 0.04958755 0.002658268 −153.5409135 8.467946 8.4362921 5.9741452 1.0866873 1.2054667 0.6019289 C9orf114 −1.863998936 0.04958755 0.000702078 −153.5923215 8.4152951 8.3496496 8.2114624 1.0866873 1.2054667 0.6019289 CDKN2A −1.347283072 0.04958755 0.003460644 −154.5706385 9.5335435 8.0162816 8.4775892 4.1976103 1.2054667 0.6019289 CHKA −0.927505586 0.061709548 0.014920164 −155.0729073 8.467946 8.4822695 9.7536389 7.8656068 1.2054667 0.6019289 ERLEC1 −0.832845493 0.081776009 0.025235497 −155.0729073 10.3104277 8.4822695 7.8994736 8.7262907 1.2054667 0.6019289 OTUD7B −1.869000125 0.04958755 0.000678007 −156.2921342 8.493568 8.23616 8.3346422 1.0866873 1.2054667 0.6019289 MAGI2 −0.82686788 0.083599382 0.026238466 −159.0433565 8.518743 8.2035936 8.6427428 8.1924923 1.2054667 0.6019289 ADIPOR2 −0.879146254 0.069835403 0.0193244 −160.8775054 8.5352855 7.9782827 8.7269332 7.5976045 1.2054667 0.6019289 GPATCH3 −0.948649699 0.059219172 0.013391639 −160.9098586 8.8316181 8.5355756 8.050877 7.0434341 1.2054667 0.6019289 TMEM39B −1.838788308 0.04958755 0.000766268 −160.9864594 8.016332 8.4174829 8.4481275 1.0866873 1.2054667 0.6019289 RAB11FIP1 −0.899579378 0.066432398 0.017171628 −162.0659195 8.6687278 9.7782453 7.9423658 7.9400838 1.2054667 0.6019289 SLC45A4 −1.483476478 0.04958755 0.002353366 −162.711655 8.5516405 8.8410048 8.4872775 3.4605153 1.2054667 0.6019289 LOC646214 −1.090455887 0.050995256 0.007788654 −162.711655 8.5516405 8.4912918 8.6938442 6.0269554 1.2054667 0.6019289 FBXO10 −1.81572425 0.04958755 0.000822434 −163.1950704 8.2244688 7.9523826 8.5716641 1.0866873 1.2054667 0.6019289 SCD −1.710166439 0.04958755 0.001199551 −163.6483896 10.2288728 7.9653908 7.9563845 1.0866873 1.2054667 0.6019289 PTRH1 −1.294375343 0.04958755 0.003982187 −163.6483896 9.6136199 9.7103237 7.9563845 5.0495858 1.2054667 0.6019289 METTL22 −1.185531397 0.049897122 0.005606194 −163.6483896 9.247621 8.7611989 7.9563845 5.3405168 1.2054667 0.6019289 NRBP1 −1.160150061 0.04991757 0.006207173 −164.5041865 12.6487544 12.0471643 11.9011612 4.6851838 9.3795682 0.6019289 PRPF3 −1.018931031 0.053434625 0.010008826 −164.5458051 8.5678121 8.6846063 8.1022182 6.4088472 1.2054667 0.6019289 NT5C2 −1.552180589 0.04958755 0.001960202 −164.7256029 8.4506083 8.7980224 6.5278107 1.0866873 1.2054667 0.6019289 USP13 −1.886083484 0.04958755 0.000621841 −165.7213753 8.4593032 8.4912918 8.2910567 1.0866873 1.2054667 0.6019289 HADHB −1.732147353 0.04958755 0.001095242 −166.2679949 9.9179761 8.464054 7.6289155 1.0866873 1.2054667 0.6019289 C15orf48 −1.831484384 0.04958755 0.000790339 −166.4113908 7.9805393 8.6608125 8.3664885 1.0866873 1.2054667 0.6019289 C9orf80 −0.969701651 0.057171148 0.012311642 −166.7468171 8.7560036 8.5869821 8.257481 6.9599943 1.2054667 0.6019289 FAM189B −1.805915755 0.04958755 0.000894648 −168.3958074 8.8906661 8.1476275 7.9976413 1.0866873 1.2054667 0.6019289 CAPN2 −0.972188703 0.056976583 0.01211827 −169.9782824 8.8316181 9.3022264 8.0111355 7.1725999 1.2054667 0.6019289 LARP4B −1.00590607 0.054519995 0.010609003 −170.0482589 8.6152671 9.0011699 8.5533334 6.9310735 1.2054667 0.6019289 PDPK1 −1.028509852 0.053066061 0.009711947 −170.5856686 8.7057364 8.0162816 8.7269332 6.3662802 1.2054667 0.6019289 NAT10 −1.120056376 0.050341156 0.006980663 −170.965335 8.6230267 9.0262169 8.3664885 5.9133149 1.2054667 0.6019289 SLC34A2 −1.630410002 0.04958755 0.001536548 −171.6960137 8.5104001 11.8278786 7.4423001 1.0866873 1.2054667 0.6019289 FBXL15 −1.815165712 0.04958755 0.000830458 −172.063791 9.625257 8.0287286 8.4678353 1.0866873 1.2054667 0.6019289 DNAJA2 −0.952611676 0.058717048 0.013163765 −172.2762996 8.3790957 9.0324114 8.6340471 7.335969 1.2054667 0.6019289 NDOR1 −1.862220108 0.04958755 0.000710102 −174.6336406 8.6536544 8.136169 8.4078853 1.0866873 1.2054667 0.6019289 FAM214B −1.750957202 0.04958755 0.001055123 −174.6336406 8.6536544 7.5303978 8.5533334 1.0866873 1.2054667 0.6019289 S100A16 −1.00864516 0.054374712 0.010506299 −174.7257144 9.6633833 11.33617 8.050877 8.0784109 1.2054667 0.6019289 DEAF1 −1.808014479 0.04958755 0.000870577 −175.7747745 8.720278 8.5442716 7.8096632 1.0866873 1.2054667 0.6019289 TEP1 −0.934595998 0.060960411 0.014399422 −176.308194 8.6984102 8.9884813 8.0638846 7.335969 1.2054667 0.6019289 GSC −1.738117957 0.04958755 0.001071171 −176.8823292 9.237547 7.4949535 8.5533334 1.0866873 1.2054667 0.6019289 ADRBK1 −0.968704049 0.057313185 0.012403113 −177.4479242 8.6536544 8.6767186 8.7987201 7.244891 1.2054667 0.6019289 PRSS8 −1.655758772 0.04958755 0.001416192 −177.6706583 8.559749 11.5049261 7.5008617 1.0866873 1.2054667 0.6019289 CROCCP2 −1.737347339 0.04958755 0.001087218 −178.0132167 9.1327388 7.4768994 8.5625279 1.0866873 1.2054667 0.6019289 TCP11L1 −1.087355091 0.051099543 0.007916232 −178.0132167 9.6406286 9.3022264 8.5625279 1.0866873 1.2054667 6.7657063 NCKAP5L −0.842203504 0.078867347 0.023727834 −180.6579828 8.5838045 8.7760413 9.7656312 1.0866873 1.2054667 8.818351 RC3H2 −1.049708942 0.051974546 0.009026719 −181.9702575 8.7130255 8.1589958 8.7350882 6.2771857 1.2054667 0.6019289 DOCK9 −1.840029634 0.04958755 0.000758244 −184.7214906 8.7346746 7.9523826 8.6252987 1.0866873 1.2054667 0.6019289 SEMA6A −0.809221506 0.089275781 0.029224906 −186.8450595 9.7650691 8.1476275 9.1122062 9.244132 1.2054667 0.6019289 PRPS1 −0.897868827 0.06669982 0.017325684 −186.8574797 8.8249055 8.5953745 8.7512612 7.9254928 1.2054667 0.6019289 ADRA2C −1.241808339 0.04958755 0.004704325 −187.3855785 11.9412356 8.8480457 8.151795 5.7241063 1.2054667 0.6019289 ST14 −1.752477485 0.04958755 0.001047099 −187.6284116 8.6384218 11.1103098 7.9840197 1.0866873 1.2054667 0.6019289 ENTPD4 −1.073368374 0.051291304 0.008262056 −187.8989939 9.5169807 8.715733 8.7592802 6.7442069 1.2054667 0.6019289 SLC22A23 −1.780900655 0.04958755 0.000950814 −188.3231904 10.2237788 8.1589958 8.2799514 1.0866873 1.2054667 0.6019289 SHROOM3 −1.798755562 0.04958755 0.000902672 −188.9680657 8.559749 10.5653425 8.1639276 1.0866873 1.2054667 0.6019289 USP39 −0.84736959 0.077498921 0.022933483 −190.4529957 9.4400009 8.9431715 8.6599785 1.0866873 1.2054667 8.7423946 JAGN1 −1.291021385 0.04958755 0.004014282 −190.5505537 10.0066589 8.9884813 8.1759589 5.0495858 1.2054667 0.6019289 PDE4D −0.892584353 0.067480686 0.017880928 −191.2794541 9.1108314 8.181467 9.1492942 8.0915413 1.2054667 0.6019289 SCARB1 −1.236087204 0.04958755 0.004792586 −192.8863826 8.1935364 8.8895842 9.2090644 5.1531951 1.2054667 0.6019289 TPRG1L −0.992402994 0.055641947 0.011182701 −193.8718297 11.359536 10.4543796 10.2078722 9.4313502 2.8554202 0.6019289 REEP4 −1.866626073 0.04958755 0.000686031 −193.8922739 8.8045782 8.7234108 8.0638846 1.0866873 1.2054667 0.6019289 SLC26A6 −1.615837809 0.04958755 0.001632833 −195.5946241 8.6984102 6.8213295 9.2551594 1.0866873 1.2054667 0.6019289 MOK −0.890946565 0.067801994 0.018099976 −196.1074499 8.4242047 8.7980224 8.7021879 1.0866873 7.89754 0.6019289 FNBP4 −0.969143352 0.057284566 0.012371018 −196.5904012 8.7057364 8.5615078 8.8891965 1.0866873 7.2874192 0.6019289 UPK3B −1.89395178 0.04958755 0.000597769 −196.6435107 8.8249055 8.23616 8.5987306 1.0866873 1.2054667 0.6019289 MMP19 −0.967039148 0.057324142 0.012475327 −197.1919891 8.9473922 8.225386 10.3151209 7.8347051 1.2054667 0.6019289 USP40 −1.932792181 0.04958755 0.000517532 −197.5605898 8.8316181 8.5869821 8.4775892 1.0866873 1.2054667 0.6019289 TACR2 −1.883823606 0.04958755 0.000629864 −201.1262655 8.1512337 8.738645 9.0869404 1.0866873 1.2054667 0.6019289 CCBP2 −0.942508549 0.059875002 0.013825724 −201.5692884 8.7418194 9.1106081 8.7350882 1.0866873 7.7510357 0.6019289 THAP3 −0.881810206 0.069395654 0.01905079 −203.5217256 9.3018043 8.8410048 8.8745057 1.0866873 1.2054667 8.3908876 C13orf33 −0.886817333 0.068383167 0.018525235 −204.5632422 9.7403116 8.5953745 8.8818698 8.5567575 1.2054667 0.6019289 LOX −1.01904388 0.053434625 0.009992779 −204.7929812 10.4124568 9.7371189 8.2799514 7.8190025 1.2054667 0.6019289 RRP9 −1.638655462 0.04958755 0.001496429 −204.8972254 8.8842233 10.0465526 8.685452 3.1012538 1.2054667 0.6019289 MTA3 −1.075537391 0.051291304 0.008197866 −204.8972254 8.8842233 8.8124926 9.0676963 6.6408414 1.2054667 0.6019289 PPP1R3F −1.864704058 0.04958755 0.000694054 −205.1545868 9.6329633 8.136169 8.7672549 1.0866873 1.2054667 0.6019289 PAM16 −1.555059152 0.04958755 0.001944155 −205.351523 8.9161535 8.7686392 6.4897707 1.0866873 1.2054667 0.6019289 MESTIT1 −1.881839333 0.04958755 0.000637888 −205.5524001 8.7700497 8.1589958 9.3107812 1.0866873 1.2054667 0.6019289 FAM73B −0.959679933 0.058066829 0.012818743 −207.4163729 8.9287302 8.5091687 8.7830733 1.0866873 7.4040744 0.6019289 INO80 −0.997498753 0.055362341 0.011034261 −208.5204676 9.6018881 8.7907325 8.7104835 1.0866873 7.4857665 0.6019289 ZNF767 −1.956547657 0.04958755 0.000469389 −208.539735 8.7908658 8.9031688 8.5159583 1.0866873 1.2054667 0.6019289 CLDN4 −1.482706099 0.04958755 0.00236139 −209.5404697 9.5979562 9.2711329 8.313014 1.0866873 3.9031434 0.6019289 FAM50A −0.881296819 0.06950889 0.019093316 −209.6781596 9.625257 8.5615078 8.7987201 1.0866873 8.5314896 0.6019289 HTT −1.944746855 0.04958755 0.000501484 −210.8123442 8.6307448 8.5268269 8.9252822 1.0866873 1.2054667 0.6019289 TGFB2 −1.16038771 0.04991757 0.006199149 −211.0009536 8.3230346 10.5865465 10.992779 7.1725999 1.2054667 0.6019289 TAOK2 −1.902682465 0.04958755 0.000573698 −212.4698427 8.3973089 8.936581 8.4381717 1.0866873 1.2054667 0.6019289 TLE1 −0.868164597 0.072080134 0.020475808 −212.4698427 9.4400009 8.936581 8.8521851 8.7759375 1.2054667 0.6019289 PJA1 −1.892735881 0.04958755 0.000605793 −214.2879639 9.0716745 8.4548593 8.3453359 1.0866873 1.2054667 0.6019289 EPS8L2 −1.833104284 0.04958755 0.000782316 −215.1812484 8.3513375 9.9998997 8.3664885 1.0866873 1.2054667 0.6019289 OFD1 −1.013957102 0.053847872 0.010174918 −215.1812484 8.3513375 9.1680015 9.161448 7.0964955 1.2054667 0.6019289 DGKD −1.874089809 0.04958755 0.000661959 −216.5746807 8.3606497 9.7782453 8.5625279 1.0866873 1.2054667 0.6019289 ANAPC2 −1.834056877 0.04958755 0.000774292 −217.0614504 8.9597007 7.8717699 8.9674264 1.0866873 1.2054667 0.6019289 IRX1 −1.759617278 0.04958755 0.001031052 −217.5017447 8.8515705 11.5193322 8.0111355 1.0866873 1.2054667 0.6019289 SDC1 −1.073663186 0.051291304 0.008254032 −218.1029684 8.7630437 12.0502202 8.9743323 7.7544253 1.2054667 0.6019289 GTF2IRD1 −0.973612754 0.056754796 0.012012357 −220.9871027 9.3771524 9.5029224 8.8745057 1.0866873 1.2054667 7.8974394 PARL −1.134328116 0.050038461 0.00667897 −222.2004657 10.5098386 9.4576082 8.3976469 6.7770801 1.2054667 0.6019289 MFSD7 −1.184039425 0.049897122 0.005646313 −223.1710103 9.2969617 9.0074725 8.5064613 5.7899671 1.2054667 0.6019289 ANKRD9 −1.048868371 0.051974546 0.00905079 −224.1438442 9.3018043 9.0137478 8.4481275 6.8406623 1.2054667 0.6019289 STK39 −1.908965524 0.04958755 0.000565674 −225.3654702 8.720278 9.6790785 8.4180516 1.0866873 1.2054667 0.6019289 CHPF −1.190029972 0.049809046 0.005517933 −225.3654702 10.744904 9.6349807 8.4180516 6.4903918 1.2054667 0.6019289 LAS1L −1.149041935 0.049952273 0.006414186 −225.9900776 9.0255823 9.1047412 8.7987201 6.1323043 1.2054667 0.6019289 ANKS4B −1.118435442 0.050341156 0.007036829 −226.3091709 10.6775714 10.7994659 10.0951772 8.0651599 2.8554202 0.6019289 ATG9A −1.886631915 0.04958755 0.000613817 −226.4778407 10.061939 8.9099134 8.2910567 1.0866873 1.2054667 0.6019289 AGPAT2 −1.794157386 0.04958755 0.000918719 −229.6467922 9.0773338 8.9299601 7.6804979 1.0866873 1.2054667 0.6019289 ADCYAP1R1 −0.971289785 0.057045525 0.012158389 −229.7110784 9.3162351 8.4456055 10.144994 8.0517861 1.2054667 0.6019289 PECR −0.957010345 0.058245659 0.012914226 −231.1651637 8.7839604 8.9884813 8.9394675 1.0866873 7.6833888 0.6019289 TIE1 −1.91812866 0.04958755 0.000541603 −231.1892237 9.5252859 8.4548593 8.6770107 1.0866873 1.2054667 0.6019289 DENND1A −1.87849402 0.04958755 0.000645912 −231.6954852 10.475962 8.7907325 8.458015 1.0866873 1.2054667 0.6019289 CHI3L1 −1.774527036 0.04958755 0.000966862 −234.4300037 8.9597007 9.4713525 7.5934735 1.0866873 1.2054667 0.6019289 S100A14 −1.771989246 0.04958755 0.000974886 −237.4173458 8.9779688 10.8686094 7.8250252 1.0866873 1.2054667 0.6019289 SRGAP2 −1.104682351 0.050647945 0.007470112 −240.0581031 9.8065464 8.5091687 10.3367183 7.1971015 1.2054667 0.6019289 NHEJ1 −0.918672036 0.063231386 0.015610206 −242.474132 9.2675602 9.1338402 9.0083744 1.0866873 1.2054667 8.2443879 UPP1 −1.917793944 0.04958755 0.000549627 −242.7730291 9.7997158 8.7002536 8.5253933 1.0866873 1.2054667 0.6019289 LDB1 −1.918673102 0.04958755 0.000533579 −244.4433886 8.5352855 8.5953745 9.5560578 1.0866873 1.2054667 0.6019289 CHTF18 −1.06684701 0.051378258 0.008427345 −245.5462076 8.6910467 9.1453174 10.4599237 7.3578678 1.2054667 0.6019289 SELS −1.024302775 0.053170593 0.009809837 −245.9380453 9.9645265 9.1567041 8.54408 7.4626381 1.2054667 0.6019289 SLC20A2 −1.248126382 0.04958755 0.004632111 −247.5205541 9.8302021 10.9992667 8.5533334 6.2771857 1.2054667 0.6019289 DHX38 −1.252482902 0.04958755 0.004575945 −248.926994 10.5181848 8.5615078 10.7305624 6.4501951 1.2054667 0.6019289 CBLL1 −1.119319977 0.050341156 0.007012758 −253.3288924 9.349356 9.1903345 8.9037393 6.6046733 1.2054667 0.6019289 MCCC2 −1.911762651 0.04958755 0.000557651 −253.9421132 9.5900602 9.0750432 8.2461133 1.0866873 1.2054667 0.6019289 GFER −1.955966526 0.04958755 0.000477413 −254.8395939 9.83355 8.5953745 8.9252822 1.0866873 1.2054667 0.6019289 NFATC4 −1.013099465 0.05402997 0.01022627 −258.7222436 10.7643305 9.0810319 9.220727 8.2285993 1.2054667 0.6019289 PFKP −1.187960106 0.049809046 0.005558052 −260.8052864 9.2171857 10.2542676 9.232296 6.6046733 1.2054667 0.6019289 SLC25A26 −1.040815694 0.052341914 0.009312365 −262.8883295 9.0430399 9.5725889 9.243773 7.4626381 1.2054667 0.6019289 OBSCN −1.729177598 0.04958755 0.001127337 −263.4489889 7.3365789 9.1280672 9.4559984 1.0866873 1.2054667 0.6019289 PRICKLE3 −2.003108115 0.04958755 0.000413223 −268.0959382 8.7057364 8.9627645 9.2720722 1.0866873 1.2054667 0.6019289 C11orf84 −1.673769995 0.04958755 0.001335954 −268.6965228 10.6663503 8.6447292 11.8191469 3.7493131 1.2054667 0.6019289 EIF2B4 −1.18183145 0.049897122 0.005710503 −270.8399451 9.6406286 9.2867634 8.8064803 6.2304884 1.2054667 0.6019289 HCCS −1.991827919 0.04958755 0.000437294 −274.0121903 9.6482535 9.1847836 8.6076411 1.0866873 1.2054667 0.6019289 ADC −1.809669915 0.04958755 0.000854529 −275.0685108 7.7305591 9.1903345 9.6191055 1.0866873 1.2054667 0.6019289 DPF2 −0.931796365 0.061198931 0.01460483 −276.401096 9.4134004 9.1047412 9.1973068 1.0866873 8.4387969 0.6019289 C15orf61 −0.969075173 0.057284566 0.012379042 −276.428115 9.2068962 9.3276354 9.3162272 8.1174489 1.2054667 0.6019289 MTMR10 −1.335672777 0.04958755 0.003564952 −277.4696374 9.6894845 8.8052757 9.3216528 5.1531951 1.2054667 0.6019289 SAMD4A −1.181244457 0.049897122 0.005750622 −277.8859592 8.720278 9.8218125 10.568875 6.7770801 1.2054667 0.6019289 TEAD4 −1.004156302 0.054558959 0.010696462 −277.8859592 8.720278 9.6631985 9.410896 1.0866873 7.7728978 0.6019289 STX5 −0.928270665 0.061590622 0.014850357 −278.6226398 9.9553358 9.3276354 9.0547229 8.7430302 1.2054667 0.6019289 CASP8 −1.969325796 0.04958755 0.000445318 −278.6628962 8.467946 9.3326639 9.2090644 1.0866873 1.2054667 0.6019289 CREB3 −0.991361133 0.055698998 0.011238867 −279.7937964 10.1261411 9.8916225 9.2149075 1.0866873 1.2054667 8.4683738 ACBD3 −0.844565126 0.078118626 0.023361149 −280.5942047 10.2665157 9.3276354 9.3378081 9.9323777 1.2054667 0.6019289 MOB2 −0.976739125 0.056484456 0.011880767 −281.541151 9.2425928 9.3426687 9.7211633 1.0866873 1.2054667 8.1534715 OPLAH −2.022592217 0.04958755 0.000365081 −281.9321151 9.3446707 9.0750432 8.7672549 1.0866873 1.2054667 0.6019289 C7orf43 −1.158133585 0.04991757 0.006247292 −281.9321151 9.3446707 9.2446997 9.4210413 6.5675757 1.2054667 0.6019289 TAT −1.030050114 0.05293768 0.009663002 −284.7602952 9.3633211 8.9031688 9.3590709 7.4422837 1.2054667 0.6019289 ZC3H3 −1.104871962 0.050647945 0.007462088 −285.60045 9.3633211 9.5381761 8.8745057 6.8714329 1.2054667 0.6019289 RABL3 −1.181603954 0.049897122 0.005726551 −287.0833804 10.5872439 9.9614598 8.7672549 6.8714329 1.2054667 0.6019289 CTU2 −2.057615598 0.04958755 0.000341009 −291.1895863 9.2725023 9.2919362 8.8964862 1.0866873 1.2054667 0.6019289 PDPN −0.966171861 0.057361825 0.012509027 −293.0924785 9.8402226 9.337675 9.4006788 8.5086224 1.2054667 0.6019289 UBTD1 −1.124886453 0.050330336 0.006884378 −300.0250627 9.247621 9.4344059 9.6667798 6.988347 1.2054667 0.6019289 ISCA1 −1.089904787 0.051027823 0.007827971 −300.0250627 9.2526317 9.4344059 9.5328559 7.221194 1.2054667 0.6019289 ZBTB40 −1.045224098 0.052154186 0.009167937 −300.9979004 9.1163395 9.4390763 10.1203006 7.8031272 1.2054667 0.6019289 LAT −2.000471888 0.04958755 0.000421247 −302.1405275 9.2120501 8.8410048 10.3919196 1.0866873 1.2054667 0.6019289 IRF6 −1.876038469 0.04958755 0.000653936 −302.9679493 8.8449503 12.1800439 9.1122062 1.0866873 1.2054667 0.6019289 PPP3CC −1.099484575 0.050846008 0.00757442 −304.8892519 10.1771041 9.4576082 9.0284206 7.3137327 1.2054667 0.6019289 CIB2 −1.314098684 0.04958755 0.003797641 −307.610468 9.4704275 9.1736173 10.1662594 5.7241063 1.2054667 0.6019289 APBB1 −0.880690685 0.069591194 0.019150285 −310.9834366 9.9614695 9.3673812 9.3107812 1.0866873 9.4354708 0.6019289 C16orf61 −0.96953519 0.057171148 0.012335714 −313.6447944 9.2774274 9.4984545 9.5514472 8.3537595 1.2054667 0.6019289 SSRP1 −1.096073289 0.050930656 0.007645029 −315.5687158 10.281302 9.7634255 8.9037393 7.4626381 1.2054667 0.6019289 NOL6 −1.212541297 0.049694878 0.005193774 −316.0059962 8.9349778 10.6402613 9.5092748 6.5294995 1.2054667 0.6019289 ELN −1.3107077 0.04958755 0.003813689 −317.3213699 4.7435639 9.3964882 10.4500491 1.0866873 1.2054667 0.6019289 C15orf17 −1.045359173 0.052154186 0.009159913 −322.2551404 9.4443871 9.5381761 9.5375262 7.7544253 1.2054667 0.6019289 SBF1P1 −1.18129826 0.049897122 0.005742598 −323.2009053 9.5417541 9.789261 9.1794888 6.6046733 1.2054667 0.6019289 ZNF692 −1.033090662 0.052897282 0.009585974 −326.8282723 9.6136199 9.4390763 9.9866543 1.0866873 1.2054667 8.0053615 MDM4 −0.9042061 0.06561616 0.016792907 −328.2373702 10.221225 9.5640624 9.2998271 9.3787623 1.2054667 0.6019289 CCDC127 −1.229027469 0.04958755 0.004904919 −330.1830474 9.5940136 9.5725889 9.2031976 6.1822306 1.2054667 0.6019289 IDUA −1.118108804 0.050341156 0.007052877 −330.8368735 8.9719051 9.6144818 10.7548302 7.4216382 1.2054667 0.6019289 AGFG1 −2.122998576 0.04958755 0.000252748 −332.1098859 9.5661093 9.4622042 9.1735003 1.0866873 1.2054667 0.6019289 CENPT −1.011796623 0.054077708 0.010306507 −334.2059233 9.5900602 9.9582098 9.0805542 8.0915413 1.2054667 0.6019289 KLHDC3 −1.032141646 0.052917554 0.009608441 −338.9385959 10.7234089 9.6103468 9.220727 8.3206874 1.2054667 0.6019289 CYB5R2 −0.98695882 0.056015811 0.011403354 −342.4715885 10.1928307 10.4658679 9.0217694 1.0866873 8.8521692 0.6019289 IRF7 −1.124787095 0.050330336 0.006892402 −342.8299514 9.2274023 9.626816 9.9022635 7.1725999 1.2054667 0.6019289 RNF26 −1.072597284 0.051291304 0.008286127 −344.7756292 10.2689906 9.6349807 9.4159775 7.8808129 1.2054667 0.6019289 SHF −2.06894649 0.04958755 0.000308914 −346.4853095 9.1649884 9.0385793 9.7046472 1.0866873 1.2054667 0.6019289 KRBA1 −1.952241559 0.04958755 0.000485437 −346.9535054 9.5252859 9.6869535 8.355951 1.0866873 1.2054667 0.6019289 GDI1 −1.065545116 0.051378258 0.008491535 −348.2932537 9.8731306 9.3124437 9.6496254 7.7210195 1.2054667 0.6019289 ASB6 −2.069392577 0.04958755 0.000300891 −348.8016827 9.1860944 9.789261 9.0481921 1.0866873 1.2054667 0.6019289 RASSF7 −1.843825426 0.04958755 0.000750221 −349.9097191 7.8543794 9.8641025 9.5375262 1.0866873 1.2054667 0.6019289 ATP13A3 −0.879850994 0.069719181 0.019265827 −350.3763035 9.667141 9.4576082 9.6582281 9.4920255 1.2054667 0.6019289 TAF1C −1.325813209 0.04958755 0.003677285 −351.63054 9.6633833 9.659201 9.87669 5.8529567 1.2054667 0.6019289 ZNF592 −1.154931649 0.04991757 0.006311482 −351.63054 9.6633833 9.1047412 9.6667798 6.7770801 1.2054667 0.6019289 JARID2 −1.01023974 0.054185592 0.010434085 −353.5008785 10.4673671 9.5683319 9.6710367 8.6395496 1.2054667 0.6019289 ACSL4 −1.005528462 0.054519995 0.010633074 −354.2926717 9.9274071 9.5554851 9.4057964 1.0866873 8.3250145 0.6019289 SRP72 −1.130324879 0.050131358 0.006749579 −356.6254536 11.2026761 9.3722734 9.6837325 7.7378191 1.2054667 0.6019289 PPFIA1 −0.996526487 0.055419354 0.011075183 −359.8793528 9.7615582 9.7295138 9.0932984 8.2166637 1.2054667 0.6019289 DECR2 −1.04691939 0.052136699 0.009121399 −372.2501736 9.1860944 9.626816 9.7735711 1.0866873 7.7944336 0.6019289 RA114 −1.336629914 0.04958755 0.003540881 −375.7046063 10.3807689 10.5907502 9.1553839 6.0805901 1.2054667 0.6019289 AMOTL1 −1.208284077 0.04976927 0.005275616 −377.8521646 9.5620786 9.7671448 10.3096707 6.9015613 1.2054667 0.6019289 C8orf82 −2.019365041 0.04958755 0.000373104 −378.5881171 10.1771041 9.6511726 8.685452 1.0866873 1.2054667 0.6019289 NT5DC3 −1.17835977 0.04991757 0.005854128 −379.6075768 9.1702939 11.432999 10.640089 1.0866873 7.7728978 0.6019289 FGFRL1 −1.035641328 0.052732335 0.00950333 −380.810206 9.6596157 11.0212355 10.3096707 1.0866873 1.2054667 8.9045161 TMEM63B −2.139009203 0.04958755 0.000228677 −385.181377 9.1913231 9.7371189 9.6921348 1.0866873 1.2054667 0.6019289 RMND5B −1.992047471 0.04958755 0.000429271 −387.0387096 10.4124568 9.6830214 8.5897647 1.0866873 1.2054667 0.6019289 AEN −2.131847591 0.04958755 0.000244724 −391.7638487 9.7005278 9.8916225 9.1553839 1.0866873 1.2054667 0.6019289 CPSF4 −1.04270456 0.052218844 0.009241756 −392.3083547 10.1397279 9.2177732 9.87669 8.1045532 1.2054667 0.6019289 YARS −1.309803 0.04958755 0.00383776 −394.694925 10.3738871 10.484061 9.2265231 6.2771857 1.2054667 0.6019289 SNX8 −2.066344568 0.04958755 0.000324962 −396.5456278 10.2058065 9.7180304 8.8891965 1.0866873 1.2054667 0.6019289 PLXNB1 −1.050757239 0.051900312 0.008978577 −398.5385928 10.5812817 11.4504526 9.7252629 1.0866873 1.2054667 9.1119156 POLR3E −2.154194175 0.04958755 0.000196582 −406.0831357 9.2675602 9.6869535 9.9130863 1.0866873 1.2054667 0.6019289 MIR205HG −2.005277086 0.04958755 0.000405199 −408.6922091 9.7615582 12.4031935 9.2720722 1.0866873 1.2054667 0.6019289 TTLL4 −2.149222233 0.04958755 0.000212629 −408.9376732 9.6097199 9.967938 9.2776661 1.0866873 1.2054667 0.6019289 RBM23 −1.385841948 0.04958755 0.00313167 −415.7929187 10.4993373 9.9051881 9.6879398 5.7899671 1.2054667 0.6019289 CEP104 −1.143556892 0.050004604 0.006510471 −417.738599 9.9211266 9.9119233 9.4006788 7.244891 1.2054667 0.6019289 MSC −1.176853531 0.04991757 0.005886223 −427.784312 11.3537183 9.3426687 10.3014565 1.0866873 7.7062919 0.6019289 SLC25A37 −1.264855103 0.04958755 0.004383375 −428.4907328 9.625257 11.3121855 9.9485869 6.9310735 1.2054667 0.6019289 TNRC18 −2.13855213 0.04958755 0.000236701 −430.7406434 10.8278185 9.3526046 9.8317667 1.0866873 1.2054667 0.6019289 B4GALT2 −1.200331177 0.049809046 0.005357458 −432.3340874 9.9614695 10.2436282 9.4853018 6.988347 1.2054667 0.6019289 MPHOSPH10 −2.14835658 0.04958755 0.000220653 −434.1682598 9.9675771 9.9647026 9.1973068 1.0866873 1.2054667 0.6019289 GAK −1.057736319 0.051778996 0.008811683 −439.1410845 10.3104277 9.9840074 9.4853018 8.2404369 1.2054667 0.6019289 EIF4G1 −1.150402457 0.049952273 0.006406162 −442.1707781 10.1771041 10.2934808 9.3903888 7.4626381 1.2054667 0.6019289 RPS6KA4 −2.197651511 0.04958755 0.000180534 −443.032446 9.7259714 9.9967352 9.4853018 1.0866873 1.2054667 0.6019289 TEX264 −1.506556711 0.04958755 0.002176843 −446.1966831 10.5632458 9.6631985 10.0070027 5.0495858 1.2054667 0.6019289 RBM15B −1.036998998 0.052603935 0.009421488 −447.8966482 10.3989614 10.0124887 9.8618705 8.6835719 1.2054667 0.6019289 C1orf51 −1.21586143 0.049622329 0.00512156 −449.2801383 9.4134004 10.1240072 10.1046498 1.0866873 6.8672984 0.6019289 CTPS −1.091998447 0.050952718 0.007757362 −451.6659568 10.1124251 10.2355969 9.4210413 1.0866873 7.956043 0.6019289 DUSP2 −1.071981094 0.051313496 0.008310198 −456.2474005 9.4356014 11.6916565 11.6177631 9.4157741 1.2054667 0.6019289 RBM19 −2.193707821 0.04958755 0.000188558 −465.4520309 9.949176 10.3391716 9.4311157 1.0866873 1.2054667 0.6019289 HLA-DRB5 −1.06249744 0.051458876 0.008579796 −466.3929082 11.4275778 2.406905 9.9520894 1.0866873 1.2054667 0.6019289 YY1AP1 −1.140015964 0.050038461 0.006566637 −471.4267509 9.9675771 9.7409065 10.6026947 1.0866873 7.7944336 0.6019289 PPP6R3 −1.351378153 0.04958755 0.003420525 −476.3542331 10.1013577 9.6227163 10.637916 6.1323043 1.2054667 0.6019289 ST6GALNAC4 −1.285131497 0.04958755 0.004078472 −476.986444 11.5778717 10.2569152 9.4997334 6.9310735 1.2054667 0.6019289 HIAT1 −1.322400605 0.04958755 0.003693332 −479.52554 10.688706 10.0373419 10.1109305 6.5675757 1.2054667 0.6019289 TCIRG1 −1.155969856 0.04991757 0.006279387 −486.8162289 10.9562254 9.8536456 10.1327001 7.9107527 1.2054667 0.6019289 PRDM1 −1.064407776 0.051378258 0.00852363 −489.1934451 10.1397279 9.9319425 12.6014599 9.4052958 1.2054667 0.6019289 ELTD1 −1.172245787 0.04991757 0.005934366 −489.8673135 10.150506 9.5381761 10.2959543 1.0866873 7.3757827 0.6019289 ARHGAP21 −1.097391256 0.050892627 0.007614539 −491.6744774 9.7331593 10.1470263 11.354818 8.5280696 1.2054667 0.6019289 ERI3 −1.131503515 0.050131358 0.006725508 −495.9768187 11.286905 10.7830279 9.5560578 8.3967085 1.2054667 0.6019289 SHARPIN −1.197014776 0.049809046 0.005381529 −497.5593503 10.9298789 10.4404718 9.5606537 7.5413002 1.2054667 0.6019289 NPM3 −1.209047034 0.04976927 0.005227473 −500.7244135 10.1849888 10.4543796 9.5698019 7.147675 1.2054667 0.6019289 RASSF4 −2.149457138 0.04958755 0.000204606 −501.3003551 10.0562188 9.2013727 10.2821063 1.0866873 1.2054667 0.6019289 ATG4B −1.30720084 0.04958755 0.003861831 −520.3743927 10.2288728 9.7782453 10.2848865 6.4501951 1.2054667 0.6019289 RDBP −1.292042051 0.04958755 0.004006259 −522.8798613 11.201381 10.6032881 9.6322646 6.988347 1.2054667 0.6019289 ANAPC1 −2.3237163 0.04958755 0.000140416 −524.069121 10.145127 10.094707 10.1203006 1.0866873 1.2054667 0.6019289 CNPY3 −1.326627967 0.04958755 0.00364519 −526.0449259 11.0727157 10.5823306 9.6409711 6.6761254 1.2054667 0.6019289 TFRC −1.113336621 0.050440463 0.007182861 −526.3942621 9.9522592 10.9196294 10.2454666 8.3753938 1.2054667 0.6019289 EXTL3 −1.4299608 0.04958755 0.002818743 −532.3750557 11.9295502 10.8210959 9.6582281 6.2771857 1.2054667 0.6019289 PDXDC2P −1.143231837 0.050004604 0.006518495 −547.8181585 10.1638663 10.4451226 10.1842406 1.0866873 8.0122661 0.6019289 ABCF1 −1.208532092 0.04976927 0.005251545 −560.8606471 10.4522017 10.7211001 9.7334275 7.4626381 1.2054667 0.6019289 AGPAT6 −1.093955674 0.050952718 0.007709219 −564.6375571 10.52234 10.346648 10.3096707 8.6033384 1.2054667 0.6019289 TMUB1 −1.353502195 0.04958755 0.003404477 −566.5832397 10.8577227 10.3516108 9.9968644 6.4903918 1.2054667 0.6019289 UBE3C −1.325855596 0.04958755 0.003669261 −570.3558468 10.8982541 11.0672144 9.7576474 6.8714329 1.2054667 0.6019289 JHDM1D −1.297089546 0.04958755 0.003958116 −572.2214721 10.8642847 10.0828183 10.3658965 6.9599943 1.2054667 0.6019289 HSD11B1 −2.231594237 0.04958755 0.000164487 −573.8290139 10.4146938 9.5425229 10.2511644 1.0866873 1.2054667 0.6019289 ZBTB7B −2.278605468 0.04958755 0.000156463 −574.9886042 10.2540769 10.4451226 9.7536389 1.0866873 1.2054667 0.6019289 BRF1 −1.06401508 0.051416052 0.008547701 −579.967541 10.2665157 9.9352522 10.3340363 1.0866873 8.5942324 0.6019289 GABBR1 −1.195187312 0.049809046 0.005421648 −580.0355996 10.4324661 9.7819266 10.5597209 7.522033 1.2054667 0.6019289 TNFRSF4 −1.362226553 0.04958755 0.003316216 −588.9046168 10.7034196 9.8038191 11.2319795 6.6046733 1.2054667 0.6019289 CAPG −2.338244164 0.04958755 0.000132392 −592.0104983 10.2135363 10.0738369 10.4149456 1.0866873 1.2054667 0.6019289 TMEM150A −1.377574605 0.04958755 0.003179812 −594.0935538 10.5812817 10.0647994 10.420013 6.2771857 1.2054667 0.6019289 HIVEP3 −1.958208314 0.04958755 0.000461366 −598.3038045 8.3513375 10.3114217 10.7264778 1.0866873 1.2054667 0.6019289 HIP1R −1.413085767 0.04958755 0.002931076 −623.4618933 9.8860865 11.8820494 11.102436 6.6408414 1.2054667 0.6019289 FOXF2 −2.06728355 0.04958755 0.000316938 −625.7737647 10.3761847 8.8689644 10.9478749 1.0866873 1.2054667 0.6019289 BCL9L −1.122875356 0.050330336 0.006908449 −642.4648719 10.484506 10.5329404 10.8685469 8.6748743 1.2054667 0.6019289 CARS −1.301826243 0.04958755 0.00390195 −685.8808531 11.7761924 11.7650993 10.0237431 7.8031272 1.2054667 0.6019289 OSTF1 −1.24743225 0.04958755 0.004640135 −701.2455606 11.0178549 10.0557048 11.0881817 7.704022 1.2054667 0.6019289 SH3PXD2A −1.026389057 0.053094283 0.009752066 −707.4601654 10.6719718 10.2057601 11.2175004 9.6688827 1.2054667 0.6019289 NOC4L −1.238616511 0.04958755 0.00473642 −731.7743792 11.041209 11.2734843 10.117184 1.0866873 7.9173057 0.6019289 KLC2 −1.443114232 0.04958755 0.002714435 −738.6411371 10.7341965 10.7811898 10.4021988 6.1822306 1.2054667 0.6019289 BCKDK −1.347561777 0.04958755 0.00345262 −753.36883 11.6143372 10.7626792 10.2368775 7.0964955 1.2054667 0.6019289 ACOT7 −1.228589032 0.049622329 0.00492899 −753.8409114 10.2861973 11.3311537 11.2520092 1.6938929 8.0663803 0.6019289 SPSB3 −1.09414793 0.050952718 0.007701196 −782.1046505 11.2257922 10.6979052 11.9588801 1.0866873 1.2054667 9.7618489 PVT1 −2.117228858 0.04958755 0.000260772 −785.7347293 9.7894089 12.9182925 10.8233652 1.6938929 1.2054667 0.6019289 SETD5 −1.119427798 0.050341156 0.00699671 −786.9794931 10.9684592 10.2221111 10.8869629 8.7840484 1.2054667 0.6019289 DENND5A −1.164886351 0.04991757 0.006094841 −813.8423114 10.8740722 10.6095165 11.3145693 8.7178475 1.2054667 0.6019289 HBA2 −2.438275777 0.04958755 0.000108321 −822.4406076 10.7555327 10.8892344 10.4149456 1.0866873 1.2054667 0.6019289 PANK4 −2.486263498 0.04958755 9.23E-05 −831.6759225 10.685004 10.8529448 10.786565 1.0866873 1.2054667 0.6019289 METTL17 −1.482528902 0.04958755 0.002369413 −845.7169775 10.9638836 11.0822207 10.32596 6.0805901 1.2054667 0.6019289 SCRIB −1.519020197 0.04958755 0.002128701 −853.2770769 10.9423372 11.1507321 10.6975571 6.0269554 1.2054667 0.6019289 SPSB1 −1.129664342 0.050131358 0.006765626 −861.3542886 10.7678347 10.9559296 12.1516987 9.5018945 1.2054667 0.6019289 NCOR2 −1.154796082 0.04991757 0.006319506 −871.2352855 11.0811904 10.3688475 11.3614183 8.8001347 1.2054667 0.6019289 MARS −1.807733194 0.04958755 0.000886624 −886.8629295 12.5076077 12.0185859 10.3944962 4.8170878 1.2054667 0.6019289 TBRG4 −1.635451967 0.04958755 0.001512477 −950.164405 11.5678559 11.6679794 10.4939623 5.5826351 1.2054667 0.6019289 LAMC3 −1.162042867 0.04991757 0.006151007 −1038.411561 10.7015886 11.2256293 12.4890185 9.4261769 1.2054667 0.6019289 WDR43 −1.289690541 0.04958755 0.00403033 −1056.826885 10.6474523 11.7669579 11.1999314 1.0866873 8.0305306 0.6019289 THAP4 −1.230088278 0.04958755 0.004896895 −1057.776938 11.4787224 11.4768113 10.6487486 8.5086224 1.2054667 0.6019289 LRCH4 −1.300096053 0.04958755 0.003926021 −1061.759775 10.8708171 11.2577084 11.3534943 7.8958605 1.2054667 0.6019289 PKP4 −1.409205026 0.04958755 0.002979218 −1194.433713 11.4275778 12.6207635 11.3415261 7.8031272 1.2054667 0.6019289 MMP12 −2.472561968 0.04958755 0.000100297 −1222.360855 12.3429402 11.1691215 10.8573834 1.0866873 1.2054667 0.6019289 AKT1 −1.268544805 0.04958755 0.004335232 −1249.518342 12.0300023 11.492623 11.3521694 8.7595777 1.2054667 0.6019289 CXCR7 −1.56648185 0.04958755 0.001871941 −1268.254454 12.2463976 12.0240363 10.9105574 1.0866873 6.6002221 0.6019289 CXCL1 −1.57288326 0.04958755 0.001839846 −1276.993173 10.920464 11.6489554 11.5500399 6.1822306 1.2054667 0.6019289 PLAU −1.32661482 0.04958755 0.003653214 −1394.857498 13.4225123 12.862886 11.0478309 9.1963108 1.2054667 0.6019289 MMP3 −1.782634668 0.04958755 0.000934767 −1404.352727 14.4665178 12.539371 11.0576185 5.8529567 1.2054667 0.6019289 HAPLN3 −1.425218988 0.04958755 0.002850838 −1417.732406 11.0712985 12.1433106 12.2438842 7.7210195 1.2054667 0.6019289 SLC39A13 −1.534554747 0.04958755 0.002032416 −1451.218318 11.7085155 11.8552182 11.378439 6.7770801 1.2054667 0.6019289 POLG −1.289672695 0.04958755 0.004038354 −1473.272096 11.6006476 11.7302749 12.3264891 8.9227488 1.2054667 0.6019289 TRIM8 −1.430480932 0.04958755 0.00281072 −1524.587701 12.1789072 11.1761323 12.5772823 7.8656068 1.2054667 0.6019289 FOSL1 −1.4246527 0.04958755 0.002858862 −1542.92711 11.7969209 12.7376868 11.6243638 8.0246608 1.2054667 0.6019289 NCS1 −1.354139155 0.04958755 0.003396454 −1796.820819 11.8979182 12.1056174 11.8095251 1.0866873 8.492491 0.6019289 YTHDC1 −1.178215458 0.04991757 0.005862152 −1960.202132 12.1422534 11.7110949 12.7380809 10.3342478 1.2054667 0.6019289 MMP1 −2.041983191 0.04958755 0.000357057 −1991.599689 15.9395716 12.0463993 9.4756 1.0866873 1.2054667 0.6019289 DAXX −1.729329332 0.04958755 0.001119313 −2141.805429 12.1802227 12.5964062 12.2700784 6.32242 1.2054667 0.6019289 KLC1 −1.368185449 0.04958755 0.003252026 −2146.563279 12.6482792 12.4640362 11.6697419 8.7430302 1.2054667 0.6019289 CDK16 −1.411638952 0.04958755 0.002947123 −2393.984757 12.4306649 12.4968854 12.1743664 8.5567575 1.2054667 0.6019289 FBXW5 −1.766773527 0.04958755 0.000998957 −2516.87735 13.2849926 12.5732248 11.8993481 6.2771857 1.2054667 0.6019289 SS18L2 −1.562850336 0.04958755 0.001904036 −2600.044501 12.4262368 12.4310079 12.9131587 1.0866873 7.7062919 0.6019289 KRT5 −2.422419242 0.04958755 0.000116344 −2643.241145 12.4547797 15.685283 11.4396006 1.0866873 1.2054667 0.6019289 SNORD36C −2.653171098 0.04958755 8.42E-05 −2679.580608 11.305107 12.6088953 12.4744788 1.0866873 1.2054667 0.6019289 PTPN23 −1.617863825 0.04958755 0.001616786 −2918.84222 12.9406847 13.016869 12.1131094 7.400693 1.2054667 0.6019289 PDLIM4 −1.556766622 0.04958755 0.001928107 −3067.127371 12.788139 14.1826228 12.679069 8.3967085 1.2054667 0.6019289 LOC493754 −1.710741767 0.04958755 0.001183503 −3620.335642 12.5910761 13.0273744 13.6360568 7.221194 1.2054667 0.6019289 DEXI −1.439654924 0.04958755 0.002754553 −3816.388306 13.1034589 13.1602396 12.7642174 9.1278561 1.2054667 0.6019289 TNFRSF1B −1.588927616 0.04958755 0.001743561 −4128.15949 12.9614908 13.2167497 13.6091329 8.2868394 1.2054667 0.6019289 PPP1R14B −1.486868809 0.04958755 0.002329295 −4615.324 13.4684599 13.959023 12.7741451 9.1963108 1.2054667 0.6019289 LAMA4 −1.359775376 0.04958755 0.003356335 −5076.834781 13.6103758 13.1248048 13.5151803 10.3063616 1.2054667 0.6019289

To determine if the lack of parity-associated changes in CD44⁺ cells from BRCA1/2 women could be due to differences in the cell populations identified by the three cell surface markers, FACS analysis of multiple tissue samples from control and BRCA1/2 women was performed. The relative frequency of CD44⁺ was slightly higher in control and BRCA1/2 parous compared to nulliparous control samples, which was associated with a slight decrease in the frequency of CD24⁺ cells, whereas the relative frequency of CD10⁺ cells was about the same in all groups (FIG. 9B). The increase in the relative frequency of CD44⁺ to CD24⁺ cells in parous samples could potentially be due to the increased number of lobulo-alveolar relative to ductal structures observed in parous women (FIG. 1 ), or due to the loss of CD24⁺ cells during involution, or may also reflect the presence of parity-induced stem cells described in murine mammary glands.

Example 3: Biological Pathways and Networks Affected by Parity-Related Gene Expression Changes

This example identifies biological pathways that are activated or repressed by parity.

It was investigated which signaling pathways might be affected by parity-related molecular changes. Early pregnancy specifically decreases the risk of ER+ breast tumors. Differentially expressed genes (Table 4, supra) were explored in CD44+ cells for candidate mediators of this effect. Several genes were identified that can change the response of breast tissue to steroid hormones by altering metabolism (e.g., HSD17B11, HSD17B12, and HSD17B14) or by modulating nuclear receptors (e.g., NCOR1, NCOR2, NCOA4, and NCOA7). Interestingly, androgen receptor (AR) and one of its key targets PSA (KLK3) were highly expressed in nulliparous CD44+ cells, implying active androgen signaling pathway that is decreased following pregnancy. Among genes highly expressed in parous CD44+ cells were a number of known tumor suppressors, such as Hakai/CBLL1, CASP8, SCRIB and LLGL2, and DNA repair-related genes (e.g., PRKDC, FANCB), suggesting that these cells may be more resistant to transformation in parous women.

In order to determine overall activation of specific biological functions due to parity in the cell types analyzed, pathway enrichment, network, and protein interactome analyses were performed using the MetaCore platform. The analyses are summarized in Table 10, below, which contains a full list of enriched GeneGo pathway maps in four different cell types (CD24+, CD44+, CD10+ and stromal fibroblasts) from human breast epithelium from nulliparous and parous subjects. Table 10 contains canonical pathway maps with p-values (<0.05) indicating significance of enrichment for differentially expressed genes upregulated in individual cell types (CD44+, CD24+, CD10+ and stroma) isolated from nulliparous and parous breast tissue, pathway maps, and p-value of enrichment in differentially expressed gene sets from the indicated human cell types from nulliparous and parous women. Table 10 also includes pathways enriched in genes highly expressed in virgin compared to publicly available datasets for parous rats [Blakely et al., supra]. It was found that parity had similar global effects on three of the four cell types analyzed, as pathways built on expression patterns in CD10+ and CD44+ cells and stroma cluster together for parous and nulliparous states (FIG. 10 ).

TABLE 10 List of Enriched GeneGo Pathway Maps in Four Different Breast Epithelial Cell Types p-values in Nulliparous p-values in Parous Pathway maps CD44+ CD24+ CD10+ Stroma rat CD44+ CD24+ CD10+ Stroma Cytoskeleton remodeling_Cyto- 1.05E−09 1.79E−04 3.27E−06 9.10E−05 3.77E−04 3.49E−03 0.0256     1.17E−04 skeleton remodeling Cytoskeleton remodeling_Re- 1.34E−09 1.17E−02 2.73E−02 9.98E−07  0.00412 7.52E−04 gulation of actin cytoskeleton by Rho GTPases Cytoskeleton remodeling_TGF, 1.88E−09 5.71E−08 1.46E−07 8.12E−04 2.69E−03 6.92E−03 1.92E−02 7.29E−03 2.63E−04 WNT and cytoskeletal remodel- ing Cell adhesion_Chemokines 2.69E−07 3.55E−05 1.03E−05 3.54E−04 3.88E−03 0.0217 2.84E−02 4.53E−02 and adhesion Cytoskeleton remodeling_Role 6.44E−07 1.40E−04 9.01E−05 0.00934   of PKA in cytoskeleton re- organisation Development_MAG-dependent 1.54E−06 1.45E−02 3.82E−02 1.71E−02 1.12E−02 0.0318    inhibition of neurite outgrowth Role of DNA methylation in pro- 2.40E−06 7.26E−03 1.50E−03 6.35E−03 0.00478   4.82E−03 gression of multiple myeloma Cell adhesion_Histamine H1 3.24E−06 7.62E−06 6.00E−03 0.0205     0.00325   receptor signaling in the inter- ruption of cell barrier integrity Cell adhesion_Alpha-4 integrins 3.71E−06 1.02E−02 6.75E−03 7.85E−03 0.0221 0.0334    in cell migration and adhesion Stem cells_Response to hypoxia 4.22E−06 3.68E−03 in glioblastoma stem cells Development_WNT signaling 5.42E−06 4.58E−03 5.02E−03 1.38E−02 0.00283   6.24E−06 pathway. Part 2 Development_Slit-Robo 6.19E−06 1.32E−04 3.54E−03 8.20E−03 4.54E−03 signaling Cytoskeleton remodeling_Fi- 8.94E−06 1.17E−03 7.71E−04 8.39E−04 bronectin-binding integrins in cell motility Oxidative phosphorylation 9.31E−06 1.25E−07 5.50E−03 2.34E−13 Cell adhesion_Role of tetra- 1.02E−05 5.25E−04 4.99E−05 spanins in the integrin-mediated cell adhesion Cell cycle_Role of Nek in cell 1.27E−05 7.84E−03 9.44E−04 1.60E−05 5.46E−03 0.0196    cycle regulation Signal transduction_PKA 1.64E−05 1.47E−02 2.59E−03 3.46E−02 0.0356     signaling Blood coagulation_Blood 1.86E−05 6.50E−04 2.90E−03 coagulation Cell adhesion_ECM remodeling 2.09E−05 2.54E−08 1.01E−06 2.90E−03 0.0000897 Inhibitory action of Lipoxin A4 2.45E−05 4.38E−02 6.75E−03 3.60E−02 0.00123   on PDGF, EGF and LTD4 signaling Stem cells_WNT/Beta-catenin 2.48E−05 4.20E−03 0.0118     and NOTCH in induction of osteogenesis HIF-1 in gastric cancer 3.00E−05 9.13E−03 1.60E−03 2.68E−02 0.0181    Cell adhesion_Plasmin signaling 3.33E−05 7.32E−07 1.41E−02 0.00805   Development_Lipoxin inhibitory 3.33E−05 4.80E−02 7.80E−03 3.95E−02 0.00144   action on PDGF, EGF and LTD4 signaling Cell adhesion_Integrin-mediated 3.84E−05 1.11E−02 1.02E−02 9.18E−03 1.81E−03 0.000871  cell adhesion and migration Cytoskeleton remodeling_Re- 5.92E−05 4.20E−03 5.25E−03 verse signaling by ephrin B Immune response_IL-1 7.06E−05 1.50E−03 6.35E−03 signaling pathway Cell adhesion_Endothelial cell 7.46E−05 4.30E−04 2.36E−03 contacts by junctional mechanisms Signal transduction_cAMP 7.78E−05 1.87E−02 2.53E−03 0.00751   signaling Regulation of CFTR 7.82E−05 1.98E−02 2.57E−04 3.91E−04 1.08E−03 2.12E−02 1.13E−02 activity (norm and CF) Development_TGF-beta- 1.13E−04 3.86E−04 4.37E−04 2.52E−04 1.40E−03 0.00597   6.19E−03 dependent induction of EMT via RhoA, PI3K and ILK. Role of stellate cells in pro- 1.16E−04 9.06E−03 7.55E−06 1.92E−04 1.57E−03 0.00135   gression of pancreatic cancer Cell cycle_Influence of Ras and 1.18E−04 3.51E−05 1.73E−02 3.23E−03 4.07E−02 0.000894   2.90E−02 Rho proteins on G1/S Transition Stem cells_NOTCH1- 1.30E−04 induced self-renewal of glioblastoma stem cells Stem cells_Pancreatic cancer 1.30E−04 3.68E−03 1.36E−06 0.000276  stem cells in tumor metastasis Tumor-stroma interactions in 1.44E−04 5.38E−05 8.16E−04 pancreatic cancer Stem cells_Regulation of lung 1.66E−04 2.88E−05 2.41E−02 epithelial progenitor cell differentiation LKB1 signaling pathway in lung 1.66E−04 9.23E−04 1.33E−02 6.90E−04 6.32E−04 0.000598  cancer cells Immune response_CCR3 1.68E−04 3.21E−03 4.15E−02 1.76E−02 1.17E−04 0.000191  signaling in eosinophils Non-genomic signaling of ESR2 1.76E−04 4.00E−02 1.81E−03 0.00451   (membrane) in lung cancer cells Blood coagulation_GPCRs in 2.20E−04 2.73E−02 1.18E−03 0.0283    platelet aggregation Cytoskeleton remodeling_Role 2.55E−04 1.10E−02 0.00146   of PDGFs in cell migration Stem cells_Role of BMP 2.59E−04 3.54E−03 signaling in embryonic stem cell neural differentiation Development_Hedgehog and 3.07E−04 1.71E−02 4.70E−02 0.0316     PTH signaling pathways in bone and cartilage development Stem cells_Endothelial 3.25E−04 3.98E−05 3.46E−02 0.0365    3.56E−02 differentiation during embryonic development Stem cells_Hedgehog, BMP and 3.25E−04 5.00E−02 1.41E−02 Parathyroid hormone in osteogenesis Dual role of BMP signaling 3.50E−04 1.57E−02 1.31E−03 2.99E−02 0.0306     4.69E−02 in gastric cancer IGF signaling in HCC 3.94E−04 1.61E−02 1.11E−03 1.21E−02 1.08E−04 0.0269     0.0108    Development_EGFR signaling 4.43E−04 3.61E−02 via small GTPases Development_FGF2-dependent 4.46E−04 3.56E−04 5.64E−03 0.0139 0.034     induction of EMT Cell adhesion_Cadherin-me- 4.72E−04 4.30E−04 4.09E−02 3.07E−04 diated cell adhesion Stem cells_Differentiation of 4.75E−04 6.82E−04 6.78E−06 white adipocytes Apoptosis and survival_Endo- 4.75E−04 1.76E−02 0.0419     plasmic reticulum stress response pathway Development_BMP signaling 5.69E−04 2.45E−02 1.15E−02 0.0202     Development_TGF-beta- 6.02E−04 3.70E−02 2.33E−03 3.74E−02 7.44E−03 0.00698    dependent induction of EMT via MAPK Transcription_ChREBP re- 6.25E−04 6.76E−03 0.0165 6.22E−03 4.33E−03 gulation pathway Translation_Regulation of 6.27E−04 2.05E−02 3.85E−02 0.00155    translation initiation PGE2 pathways in cancer 6.80E−04 0.0333    Immune response_Antigen 8.21E−04 2.32E−02 3.32E−03 presentation by MHC class I Muscle contraction_Regulation 8.47E−04 1.36E−03 2.89E−02 2.39E−03 0.0343     of eNOS activity in endothelial cells HBV-dependent NF-kB and 8.76E−04 1.70E−05 3.43E−02 8.47E−03 0.00814   2.99E−02 PI3K/AKT pathways leading to HCC IL-6 signaling in multiple 8.76E−04 1.08E−04 3.71E−02 9.11E−03 0.0291 8.14E−03 5.00E−03 myeloma Development_Melanocyte 8.76E−04 development and pigmentation Stem cells_Extraembryonic 9.09E−04 1.65E−03 differentiation of embryonic stem cells Stem cells_Astrocyte differen- 9.09E−04 3.09E−02 3.95E−02 tiation from adult stem cells Apoptosis and survival_BAD 9.18E−04 5.76E−03 8.02E−04 3.55E−03 3.77E−03 7.83E−04 3.78E−04 phosphorylation Apoptosis and survival_A- 9.18E−04 2.61E−02 3.55E−03 0.00377   1.49E−02 poptotic TNF-family pathways Stem cells_Auditory hair cell 1.06E−03 differentiation in embryogenesis Effect of H. pylori infection on 1.12E−03 2.38E−04 5.57E−03 gastric epithelial cells motility Development_S1P3 receptor 1.12E−03 4.78E−03 1.89E−02 0.0126    signaling pathway Development_Role of IL-8 in 1.12E−03 1.88E−03 2.00E−02 0.0212     angiogenesis Immune response_IL-9 1.13E−03 1.29E−02 3.44E−02 4.32E−02 0.0291    signaling pathway Transcription_CREB pathway 1.35E−03 2.88E−02 1.07E−03  0.00464 4.78E−03 5.07E−04 Apoptosis and survival_Gran- 1.35E−03 2.92E−02 6.98E−04 1.33E−02 0.0136     2.64E−03 zyme A signaling Cell adhesion_Gap junctions 1.35E−03 1.67E−02 4.63E−02 6.98E−04 DNA damage_Brca1 as a 1.35E−03 2.92E−02 transcription regulator Stem cells_Early embryonal 1.40E−03 1.71E−02 hypaxial myogenesis Immune response_Oncostatin 1.40E−03 1.12E−02 4.37E−02 3.16E−02 0.00115   M signaling via MAPK in human cells Stem cells_Beta adrenergic 1.40E−03 2.20E−03 1.02E−02 0.0000202 receptors in brown adipocyte differentiation ENaC regulation in airways 1.48E−03 3.27E−03 4.28E−02 (normal and CF) EGFR family signaling in 1.49E−03 7.40E−06 4.97E−03 1.91E−03 0.00101    pancreatic cancer Cell adhesion_Endothelial 1.52E−03 1.36E−02 2.59E−02 0.0423    cell contacts by non- junctional mechanisms Immune response_Inhibitory 1.62E−03 3.14E−02 7.19E−03 4.18E−05 0.000182  5.47E−03 action of Lipoxins on pro- inflammatory TNF-alpha signaling Neurophysiological pro- 1.62E−03 8.10E−03 6.00E−03 cess_Glutamate regulation of Dopamine D1A receptor signaling Neurophysiological pro- 1.62E−03 8.10E−03 2.56E−02 2.15E−04 cess_Receptor-mediated axon growth repulsion Role of cell adhesion 1.62E−03 7.19E−03 molecules in progression of pancreatic cancer Immune response_Fc 1.62E−03 8.10E−03 2.48E−02 gamma R-mediated phagocytosis in macrophages Neurophysiological 1.93E−03 3.50E−02 2.52E−04 0.0226     process_ACM regulation of nerve impulse Transcription_Transcription 1.98E−03 regulation of aminoacid metabolism G-protein signaling_Regulation 2.08E−03 4.65E−02 1.40E−02 0.0105     0.0377    of p 38 and JNK signaling mediated by G-proteins Stem cells_Role of GSK3 2.12E−03 2.17E−02 6.03E−03 0.0196    beta in cardioprotection against myocardial infarction Development_NOTCH- 2.12E−03 induced EMT HCV-dependent 2.12E−03 6.90E−04 3.16E−02 transcription regulation leading to HCC Regulation of lipid 2.29E−03 7.67E−05 2.94E−04 6.73E−03 0.00698    7.65E−04 metabolism_Insulin signaling:generic cascades Development_PDGF signaling 2.29E−03 3.70E−02 0.00664   via MAPK cascades Transport Clathrin-coated 2.30E−03 8.53E−04 1.21E−02 0.00213   vesicle cycle Stem cells_Stimulation of 2.30E−03 3.02E−03 4.60E−03 2.20E−04 0.0000954 differentiation of mouse em- bryonic fibroblasts into adipocytes by extracellular factors Immune response_MIF in innate 2.50E−03 4.50E−03 0.0425     immunity response Development_S1P2 and S1P3 2.54E−03 1.80E−02 1.46E−02 receptors in cell proliferation and differentiation Reproduction_GnRH signaling 2.61E−03 2.32E−02 0.0225     Regulation of lipid 2.61E−03 2.94E−02 4.48E−02 3.00E−04 metabolism_Stimulation of Arachidonic acid production by ACM receptors Regulation of lipid metabo- 2.76E−03 2.25E−02 1.95E−04 1.72E−02 0.0178     2.20E−03 lism_Insulin regulation of glycogen metabolism Immune response_Oncostatin 2.84E−03 3.62E−02 M signaling via JAK-Stat in human cells Development_WNT signaling 2.84E−03 3.70E−05 1.79E−03 3.62E−02 0.0006    pathway. Part 1. Degradation of beta-catenin in the absence WNT signaling Development_VEGF-family 3.00E−03 2.88E−05 0.0441    signaling Hypoxia-induced EMT in 3.01E−03 6.83E−04 0.0398    cancer and fibrosis Cell adhesion_Role of 3.01E−03 CDK5 in cell adhesion Immune response_IL-2 3.17E−03 1.22E−02 3.43E−02 2.91E−02 0.0314    2.99E−02 activation and signaling pathway Mechanisms of drug resistance 3.17E−03 1.22E−02 4.27E−02 0.0299     in multiple myeloma Activation of TGF-beta 3.20E−03 signaling in pancreatic cancer Development_NOTCH1- 3.20E−03 0.00103    mediated pathway for NF-KB activity modulation Regulation of VEGF signaling 3.20E−03 2.01E−03 in pancreatic cancer Possible pathway of TGF-beta 3.20E−03 1-dependent inhibition of CFTR expression Signal transduction_Erk 3.20E−03 1.02E−02 1.40E−03 0.0227     Interactions: Inhibition of Erk Muscle contraction_ GPCRs 3.51E−03 2.31E−04 in the regulation of smooth muscle tone Stem cells_NOTCH in inhi- 3.56E−03 1.16E−04 bition of WNT/Beta- catenin-induced osteogenesis Apoptosis and survival_Inhibition 3.56E−03 of ROS-induced apoptosis by 17beta-estradiol Development_TGF-beta 3.70E−03 1.34E−02 4.55E−02 receptor signaling TGF-beta 1-induced trans- 3.70E−03 3.28E−03 1.27E−02 2.30E−03 0.000388  activation of membrane re- ceptors signaling in HCC Beta-2 adrenergic-dependent 3.87E−03 CFTR expression Immune response_Oncostatin 3.88E−03 8.88E−03 3.66E−02 0.000851  M signaling via MAPK in mouse cells Role of osteoblasts in bone 3.88E−03 3.09E−02 2.31E−03 lesions formation in multiple myeloma Mechanisms of CAM−DR 3.88E−03 4.80E−02 3.95E−02 0.0366    in multiple myeloma Development_TGF-beta- 3.88E−03 7.80E−03 0.000216  2.55E−02 dependent induction of EMT via SMADs Stem cells_WNT and Notch 3.88E−03 7.80E−03 2.55E−02 signaling in early cardiac myogenesis PI3K signaling in gastric 4.30E−03 3.68E−03 9.62E−04 5.23E−04 6.36E−04 0.00226   2.49E−05 cancer Some pathways of EMT 4.30E−03 7.92E−04 7.66E−05 3.56E−02 0.025     in cancer cells Membrane-bound ESR1: 4.30E−03 1.18E−02 1.10E−02 interaction with G-proteins signaling Cell adhesion_Tight 4.66E−03 2.63E−03 1.00E−02 junctions Cytoskeleton remodel- 4.66E−03 1.29E−02 1.90E−03 9.08E−03 5.23E−06 0.000138  ing_Keratin filaments IGF-1 signaling in pan- 4.66E−03 2.61E−03 8.97E−03 4.32E−02 9.08E−03 0.0291    creatic cancer Stem cells_Dopamine- 4.79E−03 4.63E−02 induced expression of CNTF in adult neurogenesis Cell cycle_Role of 14-3-3 4.79E−03 1.07E−03 0.00516   proteins in cell cycle regulation Development_Thrombopoetin 4.79E−03 signaling via JAK- STAT pathway Immune response_IL-17 4.82E−03 3.05E−02 0.00571   7.94E−03 signaling pathways Suppression of TGF- 4.93E−03 7.26E−03 beta signaling in pan- creatic cancer G-protein signaling_G- 5.57E−03 1.12E−02 0.0067    Protein alpha-12 signaling pathway Translation _Regulation 5.72E−03 1.03E−03 6.82E−04 1.81E−04 0.000894   1.59E−03 of EIF4F activity G-protein signaling_Re- 5.78E−03 gulation of cAMP levels by ACM Cell adhesion_Ephrin 5.78E−03 2.52E−04 2.48E−02 signaling G-protein signaling_Cross- 6.08E−03 9.44E−03 talk between Ras- family GTPases Proteolysis_Putative 6.08E−03 8.14E−04 ubiquitin pathway Stem cells_Aberrant Wnt 6.08E−03 2.73E−02 3.07E−03 0.000622   signaling in medulloblastoma stem cells Putative role of Estrogen 6.56E−03 5.08E−03 0.00806   receptor and Androgen receptor signaling in pro- gression of lung cancer ERBB family and HGF 6.56E−03 1.91E−02 1.47E−03 3.60E−03 4.51E−02 4.53E−02 0.00806   signaling in gastric cancer Stem cells_Noncanonical 6.59E−03 9.53E−05 0.00921    WNT signaling in cardiac myogenesis K-RAS signaling in 6.72E−03 9.01E−03 8.12E−03 2.20E−02 2.46E−02 2.26E−02 1.66E−02 lung cancer G-protein signaling_Rap2A 7.03E−03 regulation pathway Transport_Macropinocytosis 7.05E−03 2.60E−02 0.000969  regulation by growth factors Development_EGFR 7.05E−03 7.64E−04 4.84E−04 0.0106     signaling pathway Dual role of TGF-beta 1 in HCC 7.59E−03 1.36E−02 Immune response_IFN alpha/ 7.59E−03 beta signaling pathway Development_Glucocorticoid 7.59E−03 2.59E−02 0.00515    receptor signaling Cell adhesion_PLAU signaling 7.76E−03 3.17E−03 2.90E−03 0.0386     0.00839   Transcription_P53 signaling 7.76E−03 7.33E−04 1.05E−02 1.40E−02 0.0377    pathway Stem cells_BMP7 in brown 7.76E−03 3.96E−03 0.0000304 adipocyte differentiation Development_Beta-adrenergic 7.77E−03 2.93E−02 receptors regulation of ERK Role and regulation of Prosta- 7.77E−03 0.0249     glandin E2 in gastric cancer Development_Leptin signaling 7.77E−03 3.70E−02 7.44E−03 0.0249     via PI3K-dependent pathway Transport_Alpha-2 adrenergic 7.77E−03 3.10E−02 3.74E−02 2.93E−02 receptor regulation of ion channels Influence of bone marrow cell 7.77E−03 2.33E−03 1.60E−03 0.00664   environment on progression of multiple myeloma Immune response_CD40 7.95E−03 4.01E−02 4.85E−03 1.61E−03 0.0278    3.47E−03 signaling Muscle contraction_ACM 8.52E−03 9.93E−04 regulation of smooth muscle contraction Stem cells_H3K4 demethylases 8.73E−03 2.17E−02 in stem cell maintenance Development_PDGF signaling 8.73E−03 1.39E−03 2.96E−02 8.83E−04 0.00354   via STATs and NF-kB Muscle contraction_Relaxin 8.94E−03 4.00E−02 0.0265 2.90E−02 1.97E−02 signaling pathway Transition of HCC cells to 9.07E−03 1.55E−02 0.0141    4.25E−02 invasive and migratory phenotype WNT signaling in HCC 9.07E−03 4.50E−03 1.42E−04 4.20E−03 0.0141    1.18E−02 Development_Neurotrophin 9.07E−03 1.42E−04 0.00934   family signaling Ubiquinone metabolism 9.10E−03 8.55E−03 9.27E−08 Immune response_Oncostatin 9.13E−03 2.73E−02 M signaling via JAK-Stat in mouse cells Androgen signaling in HCC 9.13E−03 4.73E−03 Cell cycle_Initiation of 9.37E−03 2.99E−02 0.0306     4.69E−02 mitosis Development_Leptin signaling 9.37E−03 3.60E−02 via JAK/STAT and MAPK cascades Transport_Macropinocytosis 9.84E−03 0.0176 Transport_RAB1A 9.84E−03 regulation pathway Cytoskeleton remodel_Integrin 1.02E−02 1.22E−02 1.14E−02 3.14E−04 outside-in signaling Influence of multiple 1.04E−02 3.98E−02 3.27E−02 0.0196 0.00624   myeloma cells on bone marrow stromal cells Role of metalloproteases 1.04E−02 2.45E−02 and heparanase in progression of pancreatic cancer Cytoskeleton remodel- 1.04E−02 ing_Thyroliberin in cytoskeleton remodeling Transport_ACM3 in 1.06E−02 1.71E−02 0.0465     salivary glands Transport_Intracellular 1.10E−02 2.85E−02 cholesterol transport in norm Muscle contraction_Delta 1.14E−02 2.36E−03 type opioid receptor in smooth muscle contraction G-protein signaling_Ras 1.14E−02 0.0348     family GTPases in kinase cascades (scheme) Development_Alpha-1 1.16E−02 adrenergic receptors signaling via cAMP HCV-mediated liver 1.16E−02 5.81E−03 0.0118     damage and predisposition to HCC progression via p 53 wtCFTR and delta508 traffic/ 1.16E−02 3.71E−02 2.16E−03 0.0228    Clathrin coated vesicles formation (norm and CF) Apoptosis and survival_HTR1A 1.17E−02 4.65E−02 1.00E−02 3.17E−02 0.0327     2.93E−05 signaling Immune response_Histamine 1.17E−02 4.65E−02 signaling in dendritic cells Development_GM-CSF 1.17E−02 6.92E−04 4.04E−02 3.39E−02 3.27E−02 0.00553   signaling Development_A2B receptor: 1.17E−02 4.65E−02 4.55E−02 0.00897   3.27E−02 action via G-protein alpha s Angiogenesis in HCC 1.17E−02 8.29E−04 Pro-inflammatory action of 1.17E−02 3.28E−03 3.39E−02 2.54E−03 0.0231    Gastrin in gastric cancer Chemoresistance pathways 1.22E−02 2.41E−02 1.09E−03 8.02E−04 2.20E−05 1.72E−02 7.83E−04 1.15E−02 mediated by constitutive activation of PI3K pathway and BCL-2 in small cell lung cancer Oxidative stress_Role of ASK1 1.22E−02 0.00528    under oxidative stress Stem cells_BMP signaling in 1.22E−02 1.38E−03 cardiac myogenesis Transcription_Role of VDR 1.23E−02 in regulation of genes involved in osteoporosis Stem cells_TNF-alpha, IL-1 1.33E−02 1.47E−02 4.83E−02 2.59E−03 0.0356     0.025     alpha and WNT5A-dependent regulation of osteogenesis and adipogenesis in mesenchymal stem cells Transcription_Role of Akt in 1.38E−02 5.59E−03 2.81E−03 1.49E−03 0.00869    hypoxia induced HIF1 activation Mitochondrial ketone bodies 1.38E−02 4.26E−05 biosynthesis and metabolism Signal transduction_AKT 1.40E−02 4.91E−06 1.54E−04 2.74E−05 0.00425   1.75E−04 signaling Regulation of beta-adrenergic 1.40E−02 receptors signaling in pancreatic cancer Development_Notch Signaling 1.40E−02 0.00422    Pathway Development_A2A 1.40E−02 1.34E−03 2.07E−02 0.0000291  receptor signaling Development_VEGF signaling 1.40E−02 2.64E−02 2.08E−02 and activation Apoptosis and survival_Anti- 1.40E−02 1.34E−03 4.78E−03 0.000175   apoptotic action of Gastrin Neurophysiological pro- 1.40E−02 cess_Melatonin signaling Neurophysiological pro- 1.43E−02 3.95E−02 cess_EphB receptors in dendritic spine morphogenesis and synaptogenesis Stem cells_Putative pathways 1.46E−02 6.24E−05   0.000261 of telomerase regulation in glioblastoma stem cells Cytoskeleton remodeling_Role 1.46E−02 8.91E−04 of Activin A in cytoskeleton remodeling Stem cells_H3K36 demethyl- 1.46E−02 4.24E−02 0.0142     ation in stem cell maintenance Development_Beta-adrenergic 1.50E−02 1.08E−04 0.0117 6.71E−03 receptors signaling via cAMP Effect of H. pylori infection 1.54E−02 3.27E−02 0.000141   on inflammation in gastric epithelial cells K-RAS signaling in 1.60E−02 0.0179 pancreatic cancer Development_S1P1 signaling 1.60E−02 5.36E−03 0.0139    pathway Development_Ligand- 1.60E−02 2.88E−02 4.78E−03 1.85E−02 0.0139    independent activation of ESR1 and ESR2 CFTR-dependent regulation of 1.60E−02 ion channels in Airway Epithelium (norm and CF) Mechanisms of resistance to 1.60E−02 2.81E−04 2.31E−02 2.11E−04 1.82E−04 0.0179    5.07E−04 EGFR inhibitors in lung cancer Development_Regulation of 1.64E−02 CDK5 in CNS HGF signaling in pancreatic 1.64E−02 6.21E−06 3.32E−03 0.003     4.42E−02 cancer E-cadherin signaling and its 1.67E−02 4.41E−04 1.96E−03 1.90E−03 0.000034  regulation in gastric cancer HBV signaling via protein 1.67E−02 2.61E−03 0.0285     kinases leading to HCC Development_Endothelin-1/ 1.69E−02 1.76E−02 1.32E−02 2.83E−03 1.34E−02 0.00159   EDNRA signaling Development_VEGF signaling 1.82E−02 3.14E−02 2.56E−02 via VEGFR2-generic cascades Immune response_IL-13 1.82E−02 signaling via JAK-STAT Signal transduction_Calcium 1.82E−02 6.00E−03 signaling Cytoskeleton remodeling_ACM3 1.92E−02 1.12E−02 and ACM4 in keratinocyte migration Stem cells_Role of Neuregulin 1.94E−02 7.11E−05 3.90E−03 0.0484 1 and Thymosin beta-4 in myocardium regeneration after infarction Cholesterol and Sphingolipids 1.94E−02 0.014     transport/Distribution to the intracellular membrane compartments (normal and CF) Stem cells_Notch signaling in 1.94E−02 medulloblastoma stem cells Proteolysis_Putative SUMO-1 1.94E−02 5.10E−03 0.0494     pathway FGF signaling in pancreatic 2.07E−02 2.01E−03 8.12E−03 2.70E−02 0.022  1.22E−03 1.66E−02 cancer Cytoskeleton remodeling_ 2.18E−02 9.99E−03 0.0194 CDC42 in cellular processes Transcription_Role of hetero- 2.18E−02 9.99E−03 4.30E−03 2.59E−03 4.36E−02 0.000604  chromatin protein 1 (HP1) family in transcriptional silencing Immune response_MIF- 2.18E−02 9.99E−03 mediated glucocorticoid regulation Apoptosis and survival_Cer- 2.21E−02 1.61E−02 1.17E−02 1.96E−03 3.69E−04 9.21E−03 7.51E−03 amides signaling pathway Cell adhesion_Cell-matrix 2.21E−02 9.29E−05 6.14E−06 0.0475    glycoconjugates Role of histone modificators in 2.28E−02 5.92E−03 1.33E−02 0.00275    progression of multiple myeloma Cytoskeleton remodeling_RalA 2.28E−02 2.92E−02 regulation pathway Muscle contraction_S1P2 2.28E−02 2.39E−02 0.0158    receptor-mediated smooth muscle contraction EGFR signaling pathway in 2.33E−02 9.13E−03 Lung Cancer Influence of smoking on 2.33E−02 activation of EGFR signaling in lung cancer cells Development_HGF 2.33E−02 3.70E−02 2.33E−03 2.93E−02 0.0268    signaling pathway Cardiac Hypertrophy_NF- 2.33E−02 4.65E−02 2.64E−03 2.98E−02 3.69E−02 0.00119   AT signaling in Cardiac Hypertrophy Immune response_TLR 2.36E−02 3.84E−03 0.00521    signaling pathways Chemotaxis_Leukocyte 2.47E−02 2.83E−02 1.36E−03 4.01E−03 4.21E−04 chemotaxis Cytokine production by Th17 2.52E−02 cells in CF Development_PACAP 2.52E−02 signaling in neural cells Translation _Regulation of 2.52E−02 7.33E−04 2.90E−03 0.0386     0.00153   EIF2 activity Cytoskeleton remodeling_FAK 2.62E−02 1.67E−03 4.89E−03 0.000356   0.0104    signaling Inhibition of apoptosis in 2.62E−02 7.84E−03 4.89E−03 0.0381    pancreatic cancer Apoptosis and survival_Role 2.65E−02 2.66E−02 3.16E−03 0.0246    1.56E−02 of IAP-proteins in apoptosis Stem cells_Neovascularization 2.65E−02 7.71E−04 of glioblastoma in response to hypoxia Stem cells_Embryonal epaxial 2.65E−02 1.32E−03 myogenesis Inflammatory mechanisms of 2.82E−02 4.84E−02 1.94E−03 0.000647   pancreatic cancerogenesis Sorafenib-induced inhibition 2.84E−02 2.34E−02 of cell proliferation and angiogenesis in HCC IL-1 beta-dependent CFTR 2.84E−02 expression Role of IGH translocations 2.87E−02 4.50E−03 1.49E−02 0.0114 0.0141    in multiple myeloma Development_Role of 2.87E−02 Activin A in cell differenti- ation and proliferation Stem cells_H3K27 de- 2.87E−02 4.50E−03 4.20E−03 methylases in differentiation of stem cells Reproduction_Progesterone- 2.87E−02 0.0425     mediated oocyte maturation Stem cells_Regulation of 2.90E−02 6.15E−04 0.000215  endothelial progenitor cell differentiation from adult stem cells Bacterial infections in CF 2.90E−02 airways Cytokine production by Th17 2.93E−02 4.32E−02 cells in CF (Mouse model) Development_PEDF signaling 2.93E−02 3.71E−02 Immune response_Bacterial 2.93E−02 4.27E−02 infections in normal airways Apoptosis and survival_Gran- 3.06E−02 7.84E−03 2.96E−02  0.00373 0.0274    zyme B signaling Stem cells_Cooperation between 3.06E−02 3.61E−02 1.52E−04 0.0274    Hedgehog, IGF-2 and HGF signaling pathways in medullo- blastoma stem cells Proteolysis_Role of Parkin 3.11E−02 1.10E−02 5.01E−03 0.0101    2.67E−02 in the Ubiquitin-Proteasomal Pathway Immune response _Immuno- 3.20E−02 2.83E−02 1.62E−04 logical synapse formation Stem cells_Muscle progenitor 3.24E−02 0.0104    cell migration in hypaxial myogenesis Apoptosis and survival_Lympho- 3.24E−02 2.19E−02 4.68E−03 0.0465     toxin-beta receptor signaling Immune response_Gastrin in 3.38E−02 1.49E−03 4.23E−02 0.000434   0.00713   inflammatory response DNA damage_Role of SUMO in 3.50E−02 3.80E−03 4.55E−02 0.00781    p 53 regulation Transcription_Transcription 3.50E−02 0.00781    factor Tubby signaling pathways Stem cells_EGF-induced 3.51E−02 5.80E−03 1.19E−03 0.0218    proliferation of Type C cells in SVZ of adult brain Normal and pathological TGF- 3.51E−02 8.95E−03 0.00624   beta-mediated regulation of cell proliferation Chemotaxis_Inhibitory 3.63E−02 1.10E−02 6.36E−04 0.0109     2.24E−04 action of lipoxins on IL-8- and Leukotriene B4-induced neutrophil migration Mucin expression in CF via 3.63E−02 1.47E−02 0.0109     TLRs, EGFR signaling pathways Translation_Insulin regulation 3.64E−02 2.00E−04 4.24E−03 7.48E−04 0.000783 1.15E−02 of translation Immune response_Neurotensin- 3.64E−02 2.41E−02 4.24E−03 0.0115    induced activation of IL-8 in colonocytes Signal transduction_JNK 3.64E−02 2.41E−02 0.0000233  pathway Immune response_IL-23 3.66E−02 2.99E−02 0.0306     4.69E−02 signaling pathway Cytoskeleton remodeling_Neuro- 3.66E−02 2.89E−02 1.97E−03 0.00619    0.0469    filaments Development_Thyroliberin 3.87E−02 signaling Transcription_PPAR 3.87E−02 0.000148  Pathway Apoptosis and survival_Cyto- 4.00E−02 1.61E−04 0.000178  2.27E−02 plasmic/mitochondrial trans- port of proapoptotic proteins Bid, Bmf and Bim Stem cells_Role of PKR1 and 4.00E−02 0.0334    2.27E−02 ILK in cardiac progenitor cells Apoptosis and survival_Role 4.00E−02 4.38E−02 6.75E−03 3.60E−02 3.34E−02 5.28E−03 0.0241    of CDK5 in neuronal death and survival Development_CNTF receptor 4.00E−02 3.60E−02 3.34E−02 2.27E−02 0.00463   signaling wtCFTR and deltaF508 traffic/ 4.00E−02 1.28E−02 Membrane expression (norm and CF) Chemotaxis_CXCR4 signaling 4.00E−02 6.75E−03 3.60E−02 0.0241    pathway G-protein signaling_Proinsulin 4.02E−02 4.45E−06 1.56E−02 1.21E−02 1.17E−02 2.53E−03 7.75E−04 1.42E−03 C-peptide signaling Apoptosis and survival_TNFR1 4.08E−02 6.48E−03 1.61E−02 0.0189    1.66E−02 signaling pathway Immune response_IL-10 4.26E−02 9.09E−03 2.36E−03 3.41E−02 0.0348     signaling pathway Neurophysiological 4.26E−02 1.80E−02 4.09E−02 1.46E−02 2.13E−03 3.48E−02 0.00136   process_Dopamine D2 receptor transactivation of PDGFR in CNS Stem cells_Insulin, IGF-1 and 4.43E−02 1.26E−04 0.0129 2.83E−03 9.70E−08 TNF-alpha in brown adipocyte differentiation Development_Angiopoietin- 4.53E−02 1.15E−02 3.09E−02 3.95E−02  0.00118 0.00805   Tie2 signaling Anti-apoptotic action of 4.53E−02 1.15E−02 8.88E−03 5.92E−03 3.66E−02 6.12E−03 2.65E−02 Gastrin in pancreatic cancer Development_Regulation 4.53E−02 8.88E−03 2.48E−02 0.0255     of telomere length and cellular immortalization Development_Flt3 signaling 4.55E−02 2.88E−02 6.34E−03 2.27E−02 1.79E−02 2.07E−02 1.08E−03 2.89E−03 Pancreatic cancer cell resistance 4.91E−02 2.05E−02 4.61E−02 2.81E−03 0.0385 0.00254   to Tarceva (erlotinib) Immune response_Signaling 4.91E−02 pathway mediated by IL-6 and IL-1 Apoptosis and survival_FAS 2.64E−02 2.74E−05 0.000131  4.22E−03 signaling cascades TTP metabolism    0.0000608 Resistance of pancreatic cancer 1.29E−04 0.00105   4.53E−03 cells to death receptor signaling Transcription_Assembly of RNA   0.000136 0.0257    Polymerase II preinitiation complex on TATA-less promoters Development_PIP3 signaling 2.29E−03 4.70E−05 3.38E−04 1.39E−03 6.60E−05 1.24E−04 in cardiac myocytes HCV-dependent regulation  0.00035 0.0387    of RNA polymerases leading to HCC Stem cells_H3K9 demeth- 4.62E−04 4.36E−02 1.98E−02 3.37E−02 ylases in pluripotency maintenance of stem cells Inhibition of apoptosis in gastric 6.32E−04 0.00333   6.61E−04 cancer Cell cycle_Start of DNA 3.61E−02  0.00067 0.000883  replication in early S phase Apoptosis and survival_Caspase 1.64E−03   0.000816 0.00105   cascade Immune response_BCR 7.76E−04 9.79E−04 1.29E−02 4.15E−03 8.06E−03 pathway Immune response_ICOS 9.01E−03 1.40E−03 1.40E−03 0.0246    6.19E−03 pathway in T-helper cell Cell cycle_The metaphase  0.00141 checkpoint Inhibitory action of Lipoxins on 1.85E−02 1.46E−03 0.0194     4.90E−04 neutrophil migration DNA damage_NHEJ 3.16E−02 1.67E−03 0.0297    1.18E−02 mechanisms of DSBs repair Cytoskeleton remodel- 5.17E−04 1.67E−03 2.97E−02 1.18E−02 2.89E−04 ing_Alpha-1A adrenergic receptor-dependent inhibition of PI3K Regulation of metabo-  0.00186 lism_Triiodothyronine and Thyroxine signaling Cell cycle_Chromosome 2.70E−03 0.00000331 condensation in prometaphase Development_IGF-1 receptor 2.47E−05 5.23E−04 2.77E−03 9.87E−03 6.69E−04 2.24E−04 signaling dCTP/dUTP metabolism 0.003  dGTP metabolism  0.00332 Inhibition of RUNX3 signaling 4.63E−02  0.00336 0.00739   in gastric cancer Apoptosis and survival_Beta-2  0.00412 8.69E−03 6.09E−03 adrenergic receptor anti- apoptotic action Signal transduction_Activin A 1.15E−02 4.38E−03 0.00105   4.53E−03 signaling regulation Stem cells_Fetal brown fat cell 4.00E−03  0.00447 1.41E−02 8.81E−03 differentiation Immune response_CXCR4 4.38E−02 6.75E−03 3.60E−02 5.11E−03 0.00711   5.28E−03 signaling via second messenger dATP/dITP metabolism  0.00573 Signal transduction_PTEN 2.01E−03 6.69E−03 5.97E−03 0.0246    6.19E−03 pathway Microsatellite instability in  0.00601 0.00177   gastric cancer Inhibition of TGF-beta 6.01E−03 0.0117    3.06E−02 signaling in gastric cancer Immune response_Regulation of 3.44E−02 1.90E−03 6.82E−03 1.68E−03 2.85E−02 5.95E−03 T cell function by CTLA-4 DNA damage_DNA-damage- 4.67E−02  0.00747 0.00337   induced responses Stem cells_Self-renewal of  0.00756 0.029     adult neural stem cells Regulation of degradation of 1.67E−02 8.44E−03 0.00869    deltaF508 CFTR in CF Transcription_Sin3 and NuRD 3.46E−03  0.00892 3.47E−02 in transcription regulation Blood coagulation_GPIb-IX-V-  0.00952 1.11E−02 dependent platelet activation Transcription_Receptor- 3.96E−03 1.32E−02 5.03E−04 1.01E−02 0.00238    8.39E−03 mediated HIF regulation Stem cells_Signaling path- 5.00E−02 1.41E−02 1.05E−02 0.0365    3.56E−02 ways in embryonic hepatocyte maturation Apoptosis and survival_nAChR 2.61E−02 2.13E−02 1.15E−02 0.0118     in apoptosis inhibition and cell cycle progression Stern cells_Role of growth 3.23E−03 0.0129 0.000583  factors in the maintenance of embryonic stem cell pluripotency Apoptosis and survival_Anti- 5.10E−03 1.09E−06 1.29E−02 0.0156    6.61E−04 apoptotic TNFs/NF-kB/ Bcl-2 pathway DNA damage_Role of Brca1 2.92E−02 0.0133 and Brca2 in DNA repair Translation IL-2 regulation of 4.24E−02 3.62E−02 0.0139 3.40E−02 3.60E−03 translation DNA damage_Mismatch repair 0.0139 0.00518   Neurophysiological process_Ol- 0.0139 factory transduction DNA damage_Inhibition of 7.04E−03 3.62E−02 0.0139 telomerase activity and cellular senescence Immune response_Role of 4.91E−02 0.0142 0.0451    DAP12 receptors in NK cells Immune response_CD28 1.17E−03 1.44E−02 1.42E−02 0.0451    1.47E−02 signaling Immune response_PIP3 0.0144 1.72E−02 1.15E−02 signaling in B lymphocytes Immune response_ETV3 affect 0.0152 on CSF1-promoted macrophage differentiation Blood coagulation_GPVI- 1.57E−02 0.0157 0.0482    dependent platelet activation Inhibition of tumor suppressive 8.43E−03 1.65E−02 0.0387    1.69E−02 pathways in pancreatic cancer Transcription_Ligand- 0.0196 Dependent Transcription of Retinoid-Target genes Development_Thrombopoietin- 2.48E−02 1.99E−02 0.000252   regulated cell processes Role of alpha-6/beta-4 integrins 1.77E−03 4.35E−06 0.0199 1.52E−02 in carcinoma progression Chemotaxis_Lipoxin inhibitory 2.10E−04 6.69E−03 2.20E−02 0.0226     3.63E−03 action on fMLP-induced neutrophil chemotaxis Development_EGFR signaling 1.17E−02 0.0226 via PIP3 Stem cells_Differentiation of 0.0248 0.00805   natural regulatory T cells G-protein signaling_S1P2 8.88E−03 0.0248 receptor signaling Translation_Opioid receptors 2.61E−02 0.0267     9.24E−04 in regulation of translation Transport_RAB3 regulation 0.0271 pathway G-protein signaling_RAC1 2.61E−03 1.00E−02 0.0277 in cellular process DNA damage_Nucleotide 0.0277 excision repair Immune response_Inhibitory 3.43E−02 2.91E−02 0.0299     action of lipoxins on superoxide production induced by IL-8 and Leukotriene B4 in neutrophils Inhibitory action of Lipoxins 3.43E−02 2.91E−02 0.0299     on Superoxide production in neutrophils wtCFTR and delta508-CFTR 0.0317 4.59E−07 traffic/Generic schema (norm and CF) Apoptosis and survival_DNA- 2.03E−04 0.0327 0.0155    damage-induced apoptosis Apoptosis and survival_NGF 9.09E−03 0.0341 0.0135    signaling pathway Apoptosis and survival_APRIL 3.35E−03 3.42E−02 0.00921    and BAFF signaling Immune response_NFAT in 5.00E−02 1.10E−02 0.0346 0.00987   immune response Apoptosis and survival_Anti- 3.70E−03 5.59E−03 3.85E−02 0.0394     apoptotic TNFs/NF-kB/ IAP pathway Immune response_TCR and 0.0414 CD28 co-stimulation in activation of NF-kB Immune response_Innate 6.39E−03 4.33E−02 0.0102     immune response to RNA viral infection Immune response _IFN gamma 3.60E−03 0.044  1.77E−03 signaling pathway Immune response_CD16 1.88E−02 2.43E−03 1.37E−02 0.0472 0.0121    signaling in NK cells Immune response_Delta-type 2.13E−02 4.84E−02 0.000367   1.40E−02 opioid receptor signaling in T-cells Apoptosis and survival_p 53- 1.14E−05 0.0484 0.00352   dependent apoptosis Effect of H. pylori infection 7.92E−04 0.0365    on apoptosis in gastric epithelial cells Immune response_Histamine 1.11E−02 3.18E−02 0.029     H1 receptor signaling in immune response Immune response_IL-4- 5.92E−03 0.0136     0.0158    antiapoptotic action Development_Angiotensin 6.48E−03 2.07E−02 0.00422    0.0126    signaling via PYK2 Development_Alpha-2 3.91E−03 7.77E−03 1.68E−03 0.000168  adrenergic receptor activation of ERK Immune response_CCR5 1.26E−03 0.0212     0.00269   signaling in macrophages and T lymphocytes Development_A3 receptor 1.22E−02 0.00222    0.0214    signaling G-protein signaling_N-RAS 8.95E−03 regulation pathway Immune response_Murine 4.87E−03 1.89E−02 NKG2D signaling EML4/ALK fusion protein in 1.39E−03 2.74E−02 1.78E−02 0.0196    nonsmoking-related lung cancer Transcription_NF-kB signaling 1.79E−02 3.76E−03 0.00238    pathway Development_ERBB-family 3.96E−03 0.0105     0.0377    signaling Fructose metabolism 7.89E−03 Apoptosis and survival_Apop- 0.00619    0.0469    totic Activin A signaling Development_EPO-induced 0.00526   Jak-STAT pathway DNA damage_Role of NFBD1 1.30E−02 in DNA damage response Mechanisms of K-RAS 2.92E−02 addiction in lung cancer cells Development_EDNRB signaling 3.70E−02 0.00979    0.00553   Immune response_Role of the 0.00528    0.0241    Membrane attack complex in cell survival Regulation of lipid metabo- 1.72E−02 5.72E−06 lism_Insulin regulation of fatty acid methabolism KLF6 and regulation of KLF6 1.33E−03 0.00424    0.0379    alternative splicing in HCC Development_S1P1 receptor 3.03E−02 0.0000769 signaling via beta-arrestin Cell cycle_Cell cycle 1.13E−03 0.00278    (generic schema) Development_Regulation of 1.59E−05 0.000016  epithelial-to-mesenchymal transition (EMT) Development_S1P4 receptor 9.99E−03 8.03E−03 0.0337    signaling pathway Signal transduction_IP3 4.32E−02 4.27E−02 3.43E−02 1.78E−03 4.92E−04 0.000988  signaling Development_Endothelin-1/ 9.01E−03 1.40E−03 0.00619    0.0166    EDNRA transactivation of EGFR Cell cycle_Sister chromatid 0.0198     cohesion Glutathione metabolism/Rodent 2.16E−02 1.00E−05 version Development_Beta-adrenergic 2.32E−03 4.70E−02 3.10E−04 0.000166  receptors transactivation of EGFR Development_ACM2 and 2.64E−02 4.78E−03 0.0126    ACM4 activation of ERK Activation of pro-oncogenic 2.60E−03 2.89E−02 0.0306     TGF-beta potential in gastric cancer Stem cells_FGF10 in develop- 2.34E−02 2.62E−04 0.0168    ment of subcutaneous white adipose tissue in embryogenesis G-protein signaling_RhoA 1.02E−02 1.38E−03 3.60E−02 0.0227     regulation pathway Immune response_IL-7 1.89E−02 0.0126    signaling in B lymphocytes G-protein signaling_Rap2B 4.59E−02 regulation pathway Development_Activation 0.0152    of ERK by Alpha-1 adrenergic receptors EGF-and HGF-dependent 1.42E−03 4.63E−02 stimulation of metastasis in gastric cancer Cell cycle_Spindle assembly 8.95E−03 3.27E−02 and chromosome separation Glycogen metabolism 0.0377    Neurophysiological pro- 0.0408    cess_Delta-type opioid receptor in the nervous system Fructose metabolism/ 1.65E−02 Rodent version Inhibitory action of Lipoxins 4.20E−03 0.0425     and Resolvin E1 on neutrophil functions Immune response_PGE2 in 2.81E−02 immune and neuroendocrine system interactions Development Dopamine D2 3.14E−02 1.10E−02 1.01E−02 2.67E−02 0.0000955 receptor transactivation of EGFR Autophagy_Autophagy 7.84E−03 4.95E−03 Regulation of lipid 0.00264   metabolism_RXR- dependent regulation of lipid metabolism via PPAR, RAR and VDR Development_A1 receptor 4.21E−02 8.94E−04 0.00736   signaling Cell cycle_Role of APC 4.95E−03 in cell cycle regulation Plasminogen activators 1.15E−02 3.95E−02 0.0265    signaling in pancreatic cancer NGF activation of NF-kB 5.10E−03 5.00E−04 9.65E−04 0.0197    2.29E−03 Immune response_IL-15 4.01E−02 4.33E−02 0.00347    0.00108   signaling Cell cycle_Role of SCF 1.14E−05 5.00E−04 complex in cell cycle regulation Development_Gastrin in 0.00921    differentiation of the gastric mucosa Propionate metabolism 0.0441    p.1 Lysine metabolism 1.42E−02 0.00192   CFTR folding and 5.69E−03 0.00369    maturation (norm and CF) Development Keratinocyte 1.49E−03 differentiation Tryptophan metabolism/ 4.11E−02 0.00734   Rodent version G-protein signaling_H−RAS 1.03E−02 regulation pathway Normal wtCFTR traffic/Sorting 1.86E−04 1.18E−02 endosome formation Apoptosis and survival_Reg- 3.26E−02 0.0246    ulation of Apoptosis by Mitochondrial Proteins Immune response_IL-4 2.88E−02 signaling pathway Development_Cross-talk 1.80E−02 4.09E−02 between VEGF and Angio- poietin 1 signaling pathways Cell cycle_ESR1 regulation 3.98E−02 1.92E−04 of G1/S transition Development_Activation of 1.29E−02 4.32E−02 4.01E−02 1.46E−03 0.00595   ERK by Kappa-type opioid receptor HCV-dependent regulation of 0.000227   membrane receptors signaling in HCC Delta508-CFTR traffic/Sorting 8.14E−04 2.31E−02 0.000752  endosome formation in CF Immune response_IL-13 1.34E−02 signaling via PI3K-ERK G-protein signaling_G-Protein 0.0109    alpha-i signaling cascades Glycolysis and gluconeo- 9.01E−03 genesis p. 1 Muscle contraction_Oxytocin 3.05E−02 2.26E−02 2.33E−02 signaling in uterus and mammary gland Development_Delta-and kappa- 2.31E−02 0.000622   0.00609   type opioid receptors signaling via beta-arrestin Glutathione metabolism 1.38E−02 3.85E−06 Regulation of lipid metabo- 1.30E−04 0.0115    lism_PPAR regulation of lipid metabolism Immune response PGE2 0.0269    common pathways Immune response_HTR2A- 6.48E−03 2.81E−02 0.00257   induced activation of cPLA2 Mitochondrial unsaturated 6.00E−03 0.0152    fatty acid beta-oxidation Development_Role of HDAC 5.64E−03 3.60E−03 0.00177   and calcium/calmodulin- dependent kinase (CaMK) in control of skeletal myogenesis Development_Growth hormone 1.72E−02 3.69E−03 0.0115    signaling via PI3K/AKT and MAPK cascades Neuropeptide signaling in 4.32E−02 pancreatic cancer Apoptosis and survival_NO 0.0162     0.0333    synthesis and signaling Immune response_IL-15 2.73E−02 signaling via JAK-STAT cascade Regulation of lipid meta- 0.0432    bolism_G-alpha(q) regulation of lipid metabolism Neurophysiological pro- 4.32E−02 cess_Long-term depression in cerebellum Apoptosis and survival_Anti- 4.80E−02 0.00612    apoptotic action of membrane- bound ESR1 Development_Role of CDK5 in 1.93E−03 2.76E−02 3.60E−02 3.34E−02 0.00463   neuronal development Cell cycle_Nucleocytoplasmic 1.75E−03 0.0276     transport of CDK/Cyclins Immune response_IL-5 6.34E−03 2.27E−02 0.00289   signalling Development_Mu-type opioid 1.61E−02 0.00204    0.00751   receptor signaling Pentose phosphate pathway/ 0.025     Rodent version Phenylalanine metabolism 3.99E−02 0.00161   Glycolysis and gluconeogenesis 1.50E−02 6.87E−04 (short map) WNT signaling in gastric cancer 1.96E−03 3.61E−04 0.00908   Stem cells_Transcription 0.000615  4.59E−04 factors in segregation of hepa- tocytic lineage Development_G-Proteins 2.70E−02 0.0166    mediated regulation MAPK- ERK signaling Development_EPO-induced 2.07E−02 0.00425   PI3K/AKT pathway and Ca(2+) influx Development Angiotensin 3.41E−02 6.69E−03 0.00363   activation of Akt DNA damage_ATM/ATR 1.80E−02 regulation of G2/M checkpoint Development_SSTR1 in 0.0494     regulation of cell proliferation and migration Cytoskeleton remodeling_ESR1 4.24E−02 action on cytoskeleton re- modeling and cell migration Immune response_TREM1 2.25E−02 0.00521    signaling pathway Stem cells_FGF signaling in 0.0425     pancreatic and hepatic dif- ferentiation of embryonic stem cells Tryptophan metabolism 3.92E−02 0.0069    Triacylglycerol metabolism p.1 2.16E−02 0.0123    G-protein signaling_Rac3 2.34E−02 regulation pathway Development_Growth 3.09E−02 2.50E−04 hormone signaling via STATs and PLC/IP3 Regulation of lipid metabo- 0.000219  lism_Regulation of fatty acid synthesis: NLTP and EHHADH Oxidative stress_Angiotensin II− 4.80E−02 3.95E−02 induced production of ROS Cholesterol and Sphingolipids 2.73E−02 transport/Recycling to plasma membrane in lung (normal and CF) Development_TGF-beta- 0.0228    induction of EMT via ROS Immune response_IL-22 5.80E−03 3.27E−02 signaling pathway Cell cycle_Transition and 0.00189    termination of DNA replication Stem cells_FGF2-induced self- 0.0118     0.0408    renewal of adult neural stem cells Regulation of metabolism_Bile 0.0318    acids regulation of glucose and lipid metabolism via FXR Apoptosis and survival_NO 0.00515    0.0423    signaling in survival Signal transduction_Activa- 9.05E−04 2.63E−03 1.08E−02 3.27E−03 0.0269    tion of PKC via G-Protein coupled receptor Development_Hedgehog 3.41E−02 2.02E−03 2.10E−04 0.0246    signaling Development_GDNF 2.01E−03 0.00619    0.0166    family signaling HBV-dependent transcription 0.0469    regulation leading to HCC Butanoate metabolism 3.29E−02 0.0192    Development_ERK5 in cell pro- 2.73E−02 liferation and neuronal survival Development_FGFR signaling 1.76E−02 5.02E−03 3.23E−03 0.0134     0.029     pathway Multiple Myeloma 0.0297    (general scheme) Development_Angiotensin 3.98E−02 1.19E−03 0.0202     0.00406   activation of ERK Leucune, isoleucine and valine 0.000262  metabolism/Rodent version Development_Mu-type opioid 0.0000955 receptor signaling via Beta- arrestin Immune response_Alternative 1.79E−05 complement pathway Development_Angiotensin 2.89E−02 1.27E−02 0.00619    0.00826   signaling via beta-Arrestin Development_Transactivation 7.40E−04 0.00306   of PDGFR in non-neuronal cells by Dopamine D2 receptor Development_Membrane-bound 2.07E−02 0.00422    ESR1: interaction with growth factors signaling Transcription_Androgen 3.14E−02 6.99E−03 0.00535   2.05E−02 Receptor nuclear signaling HBV regulation of DNA repair 1.61E−02 and apoptosis leading to HCC Regulation of lipid metabo- 0.0347    lism_Regulation of lipid metabolism via LXR, NF-Y and SREBP Immune response_IL-6 4.25E−02 signaling pathway Immune response_Lectin 1.46E−04 induced complement pathway Arachidonic acid production 4.65E−02 1.27E−02 3.70E−02 0.0231    G-protein signaling_Rap1A 1.98E−02 regulation pathway Stem cells_Dopamine-induced 3.26E−02 0.0156     0.0176    transactivation of EGFR in SVZ neural stem cells Immune response_Fc epsilon 5.63E−03 2.08E−02 1.41E−02 4.66E−03 0.00881   RI pathway FGF signaling in gastric 2.73E−02 0.0489    cancer Development_FGF-family 3.09E−02 0.00805   signaling Fatty Acid Omega Oxidation 0.0241    FGFR3 signaling in 4.37E−02 0.00115   multiple myeloma Development_MicroRNA- 0.00468   dependent inhibition of EMT Cardiac Hypertrophy_Ca(2+)- 1.85E−02 1.85E−02 0.0381    dependent NF-AT signaling in Cardiac Hypertrophy Immune response_Role of 0.0347    integrins in NK cells cyto- toxicity Stem cells_MMP-14-induced 2.31E−02 COX-2 expression in glio- blastoma stem cells Hedgehog signaling in 2.52E−05 pancreatic cancer Neurophysiological pro- 0.00162   cess_GABA-A receptor life cycle HCV-dependent cytoplasmic 4.61E−02 1.67E−02 0.000227   0.000193  signaling leading to HCC Neurophysiological pro- 0.0148     0.0045    cess_NMDA-dependent post- synaptic long-term potentiation in CA1 hippocampal neurons Immune response_IL-12 2.31E−02 0.00424    signaling pathway Stem cells_Scheme: Histone 0.0156     H3 demethylases in stem cells Neurophysiological pro- 0.0149     0.0475    cess_HTR1A receptor signaling in neuronal cells Atherosclerosis_Role of 4.81E−02 2.00E−02 1.97E−04 0.0387 1.69E−02 ZNF202 in regulation of expression of genes involved in Atherosclerosis Translation_Non-genomic 4.50E−03 1.41E−02 1.18E−02 0.0408    (rapid) action of Androgen Receptor Immune response_Lipoxins 2.31E−03 0.0255     and Resolvin E1 inhibitory action on neutrophil functions Cell cycle_Regulation of 4.30E−04 0.0348     G1/S transition (part 2) Anti-apoptotic action of 1.15E−02 8.88E−03 0.00612    Gastrin in gastric cancer Development_Activation of 1.64E−03 5.80E−03 6.90E−03 0.0202     astroglial cells proliferation by ACM3 GTP metabolism 0.0311    Neurophysiological pro- 4.80E−02 cess_Thyroliberin in cell hyperpolarization and excitability Glutathione metabolism/ 1.50E−02 4.55E−06 Human version Stem cells_FGF2 signaling 0.0227     during embryonic stem cell differentiation Proliferative action of 4.58E−03 3.65E−05 4.59E−02 0.0421    Gastrin in gastric cancer Cell adhesion_Integrin 7.04E−03 3.84E−03 1.71E−02 0.0356    inside-out signaling Tissue factor signaling in 3.14E−02 Lung Cancer Development_Prolactin 2.63E−02 8.70E−03 2.00E−02 0.0406    receptor signaling Phenylalanine metabo- 3.52E−02 0.00559   lism/Rodent version Development_SSTR2 in 0.00705    0.00595   regulation of cell proliferation Immune response_CD137 7.26E−03 0.0118     signaling in immune cell Development_WNT5A 9.01E−03 2.82E−02 0.00597   signaling Translation_Translation 1.03E−03 1.32E−02 0.0419     0.029     regulation by Alpha-1 adrenergic receptors Development_Gastrin in 2.89E−03 3.91E−03 2.69E−02 2.42E−02 2.79E−03 0.00394   cell growth and proliferation Effect of H. pylori infection 2.63E−02 2.71E−02 on gastric epithelial cell proliferation Chemotaxis_CCR4-induced 4.63E−02 2.39E−02 leukocyte adhesion GTP-XTP metabolism 8.97E−03 Transcription_Ligand- 2.92E−02 dependent activation of the ESR1/SP pathway Immune response_TLR3 4.24E−02 1.58E−02 and TLR4 induce TICAM1- specific signaling pathway Development_Delta-type 1.03E−02 4.70E−02 0.00808    0.000166  opioid receptor mediated cardioprotection Development_Mu-type 1.89E−02 0.00192   opioid receptor regulation of proliferation Immune response IL-12- 2.63E−03 0.000259   induced IFN-gamma production Proliferative action of Gastrin 7.26E−03 2.27E−02 0.00108    in pancreatic cancer Cell cycle_Regulation of G1/S 3.46E−03 4.22E−02 0.0000516 3.50E−02 transition (part 1) Protein folding_Membrane 1.46E−03 2.97E−02 0.00295   trafficking and signal transduction of G-alpha (i) heterotrimeric G-protein Immune response_Classical 8.50E−06 complement pathway Transport_Rab-9 regulation 2.84E−02 5.01E−03 pathway Development_Signaling of 0.00736    Beta-adrenergic receptors via Beta-arrestins Lysine metabolism/Rodent 4.82E−03 0.00209   version G-protein signaling_G- 0.00528    0.0241    Protein beta/gamma signaling cascades Immune response_Sialic-acid 0.0179     receptors (Siglecs) signaling Leucune, isoleucine and valine 0.000212  metabolism.p.2 Neurophysiological pro- 4.63E−02 cess_Kappa-type opioid receptor in transmission of nerve impulses Stem cells_Scheme: Adult 1.37E−02 neurogenesis in the Subventricular Zone Immune response_MIF- 2.14E−03 3.14E−02 JAB1 signaling Immune response_Function 4.65E−02 1.27E−02 3.70E−02 0.00553   of MEF2 in T lymphocytes Immune response_Human 1.17E−02 NKG2D signaling Aflatoxin B1-dependent 3.98E−02 induction of HCC Neurophysiological pro- 3.88E−02 0.0442     cess_Role of CDK5 in pre- synaptic signaling Stem cells_mGluR3 signaling 4.28E−02 0.0386     0.0269    in glioblastoma stem cells G-protein signaling_G-Protein 1.02E−02 3.60E−02 0.00103    alpha-q signaling cascades DNA damage_ATM/ATR 2.44E−07 0.0178     regulation of G1/S checkpoint Pentose phosphate pathway 0.0269    Immune response_MIF- 3.41E−02 2.02E−03 3.50E−02 6.69E−03 0.00597   the neuroendocrine-macrophage connector Immune response Antiviral 1.21E−02 actions of Interferons Glycolysis and gluconeogenesis 2.53E−03 p. 2/Human version Peroxisomal branched chain 3.41E−02 fatty acid oxidation Regulation of lipid 4.49E−02 metabolism_Alpha-1 adrenergic receptors signaling via arachidonic acid Development_Angiotensin 1.58E−06 signaling via STATs Triacylglycerol metabolism p.2 1.89E−02 Glycolysis and gluconeo- 1.10E−02 genesis p.3/Human version Immune response_T cell 2.90E−03 receptor signaling pathway Glycolysis and gluconeo- 1.10E−02 genesis p.3 2-Naphthylamine and 2- 3.79E−04 Nitronaphtalene metabolism Androstenedione and 1.00E−02 testosterone biosynthesis and metabolism p.2/Rodent version Retinol metabolism/Rodent 1.47E−02 version G-protein signaling_Regulation 3.27E−02 of CDC42 activity Mitochondrial long chain 3.41E−02 fatty acid beta-oxidation Pyruvate metabolism/ 2.91E−03 Rodent version Neurophysiological pro- 6.90E−04 cess_Netrin-1 in regulation of axon guidance Regulation of lipid meta- 2.48E−02 bolism_Regulation of lipid metabolism by niacin and isoprenaline Stem cells_Scheme: 4.11E−02 Osteogenic and adipogenic differentiation of mesenchymal stem cells Pyruvate metabolism 9.11E−03 Naphthalene metabolism 2.50E−02 Transcription_Role of AP-1 1.26E−02 in regulation of cellular metabolism 1-Naphthylamine and 1- 6.00E−03 Nitronaphtalene metabolism Muscle contraction_Re- 4.91E−02 gulation of eNOS activity in cardiomyocytes Retinol metabolism 1.95E−02 Androstenedione and 8.88E−03 testosterone biosynthesis and metabolism p.2 Acetaminophen metabolism 3.90E−03 Propionate metabolism p.2 1.70E−02

Furthermore, Table 10 lists only the pathways determined to be upregulated in CD44+ cells from nulliparous women relative to CD44+ cells from parous women, and Table 12 lists the pathways that were significantly upregulated in CD44+, CD24− breast epithelial cells of parous women relative to the same cell type in nulliparous women.

The most significant pathways highly active in parous samples in all of these three cell types included apoptosis, survival, and immune response, whereas stem cells and development-related pathways were enriched only in CD44+ cells from nulliparous women (FIG. 11 ) and Table 10, above, and Table 12, below). Pathways highly active in parous stroma were enriched in energy metabolism, fatty acid metabolism and adipocyte differentiation from stem cells, which is consistent with adipose tissue development and a decrease in breast density following pregnancy. Table 13, below shows a summary of GeneGo functional enrichment analysis by protein class for differentially expressed genes in CD44+, CD24+, CD10+ and stromal cell types isolated from nulliparous and parous normal human breast. Table 13 indicates the actual and expected number of network objects in the activated dataset for a given protein class, and the ratio of the actual and expected number. In the Table, “n” is the total number of genes in the list, “R” is the number of genes showing the indicated protein class in the background list, “N” is the total number of genes in the background list, the mean value for hypergeometric distribution is calculated by the formula: (n*R/N), the z-score is calculated using the formula: ((r-mean)/sqrt(variance)), and the p-value represents the probability to have the given value of r or higher (or lower for negative z-score). The functional categories of genes affected by parity were similar in all four cell types with receptors and enzymes representing the most enriched groups (FIG. 12 and Table 13).

TABLE 11 Pathways Upregulated in Nulliparous CD44+ Cells Relative to Parous CD44+ Cells P-value in Pathway maps NP CD44+ Cytoskeleton remodeling_Role of PKA in cytoskeleton reorganisation 6.44E−07 Development_MAG-dependent inhibition of neurite outgrowth 1.54E−06 Role of DNA methylation in progression of multiple myeloma 2.40E−06 Cell adhesion_Histamine H1 receptor signaling in the interruption of cell barrier integrity 3.24E−06 Stem cells_Response to hypoxia in glioblastoma stem cells 4.22E−06 Development_WNT signaling pathway. Part 2 5.42E−06 Development_Slit-Robo signaling 6.19E−06 Cytoskeleton remodeling_Fibronectin-binding integrins in cell motility 8.94E−06 Oxidative phosphorylation 9.31E−06 Cell adhesion_Role of tetraspanins in the integrin-mediated cell adhesion 1.02E−05 Cell cycle_Role of Nek in cell cycle regulation 1.27E−05 Blood coagulation_Blood coagulation 1.86E−05 Cell adhesion_ECM remodeling 2.09E−05 Inhibitory action of Lipoxin A4 on PDGF, EGF and LTD4 signaling 2.45E−05 Stem cells_WNT/Beta-catenin and NOTCH in induction of osteogenesis 2.48E−05 HIF-1 in gastric cancer 3.00E−05 Cell adhesion_Plasmin signaling 3.33E−05 Development_Lipoxin inhibitory action on PDGF, EGF and LTD4 signaling 3.33E−05 Cell adhesion_Integrin-mediated cell adhesion and migration 3.84E−05 Cytoskeleton remodeling_Reverse signaling by ephrin B 5.92E−05 Immune response_IL-1 signaling pathway 7.06E−05 Cell adhesion_Endothelial cell contacts by junctional mechanisms 7.46E−05 Signal transduction_cAMP signaling 7.78E−05 Role of stellate cells in progression of pancreatic cancer 1.16E−04 Stem cells_NOTCH1-induced self-renewal of glioblastoma stem cells 1.30E−04 Stem cells_Pancreatic cancer stem cells in tumor metastasis 1.30E−04 Tumor-stroma interactions in pancreatic cancer 1.44E−04 Stem cells_Regulation of lung epithelial progenitor cell differentiation 1.66E−04 LKB1 signaling pathway in lung cancer cells 1.66E−04 Immune response_CCR3 signaling in eosinophils 1.68E−04 Non-genomic signaling of ESR2 (membrane) in lung cancer cells 1.76E−04 Blood coagulation_GPCRs in platelet aggregation 2.20E−04 Cytoskeleton remodeling_Role of PDGFs in cell migration 2.55E−04 Stem cells_Role of BMP signaling in embryonic stem cell neural differentiation 2.59E−04 Development_Hedgehog and PTH signaling pathways in bone and cartilage development 3.07E−04 Stem cells_Hedgehog, BMP and Parathyroid hormone in osteogenesis 3.25E−04 IGF signaling in HCC 3.94E−04 Development_EGFR signaling via small GTPases 4.43E−04 Cell adhesion_Cadherin-mediated cell adhesion 4.72E−04 Stem cells_Differentiation of white adipocytes 4.75E−04 Apoptosis and survival_Endoplasmic reticulum stress response pathway 4.75E−04 Development_BMP signaling 5.69E−04 Development_TGF-beta-dependent induction of EMT via MAPK 6.02E−04 PGE2 pathways in cancer 6.80E−04 Immune response_Antigen presentation by MHC class I 8.21E−04 Muscle contraction_Regulation of eNOS activity in endothelial cells 8.47E−04 Development_Melanocyte development and pigmentation 8.76E−04 Stem cells_Extraembryonic differentiation of embryonic stem cells 9.09E−04 Stem cells_Astrocyte differentiation from adult stem cells 9.09E−04 Stem cells_Auditory hair cell differentiation in embryogenesis 1.06E−03 Effect of H. pylori infection on gastric epithelial cells motility 1.12E−03 Development_S1P3 receptor signaling pathway 1.12E−03 Development_Role of IL-8 in angiogenesis 1.12E−03 Immune response_IL-9 signaling pathway 1.13E−03 Cell adhesion_Gap junctions 1.35E−03 DNA damage_Brca1 as a transcription regulator 1.35E−03 Stem cells_Early embryonal hypaxial myogenesis 1.40E−03 Immune response_Oncostatin M signaling via MAPK in human cells 1.40E−03 Stem cells_Beta adrenergic receptors in brown adipocyte differentiation 1.40E−03 ENaC regulation in airways (normal and CF) 1.48E−03 EGFR family signaling in pancreatic cancer 1.49E−03 Cell adhesion_Endothelial cell contacts by non-junctional mechanisms 1.52E−03 Neurophysiological process_Glutamate regulation of Dopamine D1A receptor signaling 1.62E−03 Neurophysiological process_Receptor-mediated axon growth repulsion 1.62E−03 Role of cell adhesion molecules in progression of pancreatic cancer 1.62E−03 Immune response_Fc gamma R-mediated phagocytosis in macrophages 1.62E−03 Neurophysiological process_ACM regulation of nerve impulse 1.93E−03 Transcription_Transcription regulation of aminoacid metabolism 1.98E−03 G-protein signaling_Regulation of p38 and JNK signaling mediated by G-proteins 2.08E−03 Stem cells_Role of GSK3 beta in cardioprotection against myocardial infarction 2.12E−03 Development_NOTCH-induced EMT 2.12E−03 HCV-dependent transcription regulation leading to HCC 2.12E−03 Development_PDGF signaling via MAPK cascades 2.29E−03 Transport_Clathrin-coated vesicle cycle 2.30E−03 Stem cells_Stimulation of differentiation of mouse embryonic fibroblasts into adipocytes by 2.30E−03 extracellular factors Immune response_MIF in innate immunity response 2.50E−03 Development_S1P2 and S1P3 receptors in cell proliferation and differentiation 2.54E−03 Reproduction_GnRH signaling 2.61E−03 Regulation of lipid metabolism_Stimulation of Arachidonic acid production by ACM receptors 2.61E−03 Immune response_Oncostatin M signaling via JAK-Stat in human cells 2.84E−03 Development_WNT signaling pathway. Part 1. Degradation of beta-catenin in the absence WNT 2.84E−03 signaling Development_VEGF-family signaling 3.00E−03 Hypoxia-induced EMT in cancer and fibrosis 3.01E−03 Cell adhesion_Role of CDK5 in cell adhesion 3.01E−03 Mechanisms of drug resistance in multiple myeloma 3.17E−03 Activation of TGF-beta signaling in pancreatic cancer 3.20E−03 Development_NOTCH1-mediated pathway for NF-KB activity modulation 3.20E−03 Regulation of VEGF signaling in pancreatic cancer 3.20E−03 Possible pathway of TGF-beta 1-dependent inhibition of CFTR expression 3.20E−03 Signal transduction_Erk Interactions: Inhibition of Erk 3.20E−03 Muscle contraction_GPCRs in the regulation of smooth muscle tone 3.51E−03 Stem cells_NOTCH in inhibition of WNT/Beta-catenin-induced osteogenesis 3.56E−03 Apoptosis and survival_Inhibition of ROS-induced apoptosis by 17beta-estradiol 3.56E−03 Development_TGF-beta receptor signaling 3.70E−03 TGF-beta 1-induced transactivation of membrane receptors signaling in HCC 3.70E−03 Beta-2 adrenergic-dependent CFTR expression 3.87E−03 Immune response_Oncostatin M signaling via MAPK in mouse cells 3.88E−03 Role of osteoblasts in bone lesions formation in multiple myeloma 3.88E−03 Mechanisms of CAM-DR in multiple myeloma 3.88E−03 Development_TGF-beta-dependent induction of EMT via SMADs 3.88E−03 Stem cells_WNT and Notch signaling in early cardiac myogenesis 3.88E−03 Some pathways of EMT in cancer cells 4.30E−03 Membrane-bound ESR1: interaction with G-proteins signaling 4.30E−03 Cell adhesion_Tight junctions 4.66E−03 Cytoskeleton remodeling_Keratin filaments 4.66E−03 IGF-1 signaling in pancreatic cancer 4.66E−03 Stem cells_Dopamine-induced expression of CNTF in adult neurogenesis 4.79E−03 Cell cycle_Role of 14-3-3 proteins in cell cycle regulation 4.79E−03 Development_Thrombopoetin signaling via JAK-STAT pathway 4.79E−03 Immune response_IL-17 signaling pathways 4.82E−03 Suppression of TGF-beta signaling in pancreatic cancer 4.93E−03 G-protein signaling_G-Protein alpha-12 signaling pathway 5.57E−03 G-protein signaling_Regulation of cAMP levels by ACM 5.78E−03 Cell adhesion_Ephrin signaling 5.78E−03 G-protein signaling_Cross-talk between Ras-family GTPases 6.08E−03 Proteolysis_Putative ubiquitin pathway 6.08E−03 Stem cells_Aberrant Wnt signaling in medulloblastoma stem cells 6.08E−03 Putative role of Estrogen receptor and Androgen receptor signaling in progression of lung cancer 6.56E−03 ERBB family and HGF signaling in gastric cancer 6.56E−03 Stem cells_Noncanonical WNT signaling in cardiac myogenesis 6.59E−03 G-protein signaling_Rap2A regulation pathway 7.03E−03 Transport_Macropinocytosis regulation by growth factors 7.05E−03 Development_EGFR signaling pathway 7.05E−03 Dual role of TGF-beta 1 in HCC 7.59E−03 Immune response_IFN alpha/beta signaling pathway 7.59E−03 Development_Glucocorticoid receptor signaling 7.59E−03 Cell adhesion_PLAU signaling 7.76E−03 Transcription_P53 signaling pathway 7.76E−03 Stem cells_BMP7 in brown adipocyte differentiation 7.76E−03 Development_Beta-adrenergic receptors regulation of ERK 7.77E−03 Role and regulation of Prostaglandin E2 in gastric cancer 7.77E−03 Development_Leptin signaling via PI3K-dependent pathway 7.77E−03 Transport_Alpha-2 adrenergic receptor regulation of ion channels 7.77E−03 Influence of bone marrow cell environment on progression of multiple myeloma 7.77E−03 Immune response_CD40 signaling 7.95E−03 Muscle contraction_ACM regulation of smooth muscle contraction 8.52E−03 Stem cells_H3K4 demethylases in stem cell maintenance 8.73E−03 Development_PDGF signaling via STATs and NF-kB 8.73E−03 Transition of HCC cells to invasive and migratory phenotype 9.07E−03 WNT signaling in HCC 9.07E−03 Development_Neurotrophin family signaling 9.07E−03 Ubiquinone metabolism 9.10E−03 Immune response_Oncostatin M signaling via JAK-Stat in mouse cells 9.13E−03 Androgen signaling in HCC 9.13E−03 Development_Leptin signaling via JAK/STAT and MAPK cascades 9.37E−03 Transport_RAB1A regulation pathway 9.84E−03 Cytoskeleton remodeling_Integrin outside-in signaling 1.02E−02 Role of metalloproteases and heparanase in progression of pancreatic cancer 1.04E−02 Cytoskeleton remodeling_Thyroliberin in Cytoskeleton remodeling 1.04E−02 Transport_ACM3 in salivary glands 1.06E−02 Transport_Intracellular cholesterol transport in norm 1.10E−02 Muscle contraction_Delta-type opioid receptor in smooth muscle contraction 1.14E−02 G-protein signaling_Ras family GTPases in kinase cascades (scheme) 1.14E−02 Development_Alpha-1 adrenergic receptors signaling via cAMP 1.16E−02 HCV-mediated liver damage and predisposition to HCC progression via p53 1.16E−02 wtCFTR and delta508 traffic/Clathrin coated vesicles formation (norm and CF) 1.16E−02 Immune response_Histamine signaling in dendritic cells 1.17E−02 Development_GM-CSF signaling 1.17E−02 Development_A2B receptor: action via G-protein alpha s 1.17E−02 Angiogenesis in HCC 1.17E−02 Pro-inflammatory action of Gastrin in gastric cancer 1.17E−02 Oxidative stress_Role of ASK1 under oxidative stress 1.22E−02 Stem cells_BMP signaling in cardiac myogenesis 1.22E−02 Transcription_Role of VDR in regulation of genes involved in osteoporosis 1.23E−02 Stem cells_TNF-alpha, IL-1 alpha and WNT5A-dependent regulation of osteogenesis and 1.33E−02 adipogenesis in mesenchymal stem cells Mitochondrial ketone bodies biosynthesis and metabolism 1.38E−02 Regulation of beta-adrenergic receptors signaling in pancreatic cancer 1.40E−02 Development_Notch Signaling Pathway 1.40E−02 Development_A2A receptor signaling 1.40E−02 Development_VEGF signaling and activation 1.40E−02 Apoptosis and survival_Anti-apoptotic action of Gastrin 1.40E−02 Neurophysiological process_Melatonin signaling 1.40E−02 Neurophysiological process_EphB receptors in dendritic spine morphogenesis and synaptogenesis 1.43E−02 Cytoskeleton remodeling_Role of Activin A in cytoskeleton remodeling 1.46E−02 Stem cells_H3K36 demethylation in stem cell maintenance 1.46E−02 Effect of H. pylori infection on inflammation in gastric epithelial cells 1.54E−02 Development_S1P1 signaling pathway 1.60E−02 Development_Ligand-independent activation of ESR1 and ESR2 1.60E−02 CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF) 1.60E−02 Mechanisms of resistance to EGFR inhibitors in lung cancer 1.60E−02 Development_Regulation of CDK5 in CNS 1.64E−02 HGF signaling in pancreatic cancer 1.64E−02 E-cadherin signaling and its regulation in gastric cancer 1.67E−02 HBV signaling via protein kinases leading to HCC 1.67E−02 Development_Endothelin-1/EDNRA signaling 1.69E−02 Development_VEGF signaling via VEGFR2 - generic cascades 1.82E−02 Immune response_IL-13 signaling via JAK-STAT 1.82E−02 Signal transduction_Calcium signaling 1.82E−02 Cytoskeleton remodeling_ACM3 and ACM4 in keratinocyte migration 1.92E−02 Cholesterol and Sphingolipids transport/Distribution to the intracellular membrane compartments 1.94E−02 (normal and CF) Stem cells_Notch signaling in medulloblastoma stem cells 1.94E−02 Proteolysis_Putative SUMO-1 pathway 1.94E−02 Transcription_Role of heterochromatin protein 1 (HP1) family in transcriptional silencing 2.18E−02 Immune response_MIF-mediated glucocorticoid regulation 2.18E−02 Cell adhesion_Cell-matrix glycoconjugates 2.21E−02 Cytoskeleton remodeling_RalA regulation pathway 2.28E−02 Muscle contraction_S1P2 receptor-mediated smooth muscle contraction 2.28E−02 EGFR signaling pathway in Lung Cancer 2.33E−02 Influence of smoking on activation of EGFR signaling in lung cancer cells 2.33E−02 Development_HGF signaling pathway 2.33E−02 Cardiac Hypertrophy_NF-AT signaling in Cardiac Hypertrophy 2.33E−02 Immune response_TLR signaling pathways 2.36E−02 Chemotaxis_Leukocyte chemotaxis 2.47E−02 Cytokine production by Th17 cells in CF 2.52E−02 Development_PACAP signaling in neural cells 2.52E−02 Translation_Regulation of EIF2 activity 2.52E−02 Cytoskeleton remodeling_FAK signaling 2.62E−02 Inhibition of apoptosis in pancreatic cancer 2.62E−02 Stem cells_Neovascularization of glioblastoma in response to hypoxia 2.65E−02 Stem cells_Embryonal epaxial myogenesis 2.65E−02 Inflammatory mechanisms of pancreatic cancerogenesis 2.82E−02 Sorafenib-induced inhibition of cell proliferation and angiogenesis in HCC 2.84E−02 IL-1 beta-dependent CFTR expression 2.84E−02 Development_Role of Activin A in cell differentiation and proliferation 2.87E−02 Stem cells_H3K27 demethylases in differentiation of stem cells 2.87E−02 Reproduction_Progesterone-mediated oocyte maturation 2.87E−02 Stem cells_Regulation of endothelial progenitor cell differentiation from adult stem cells 2.90E−02 Bacterial infections in CF airways 2.90E−02 Cytokine production by Th17 cells in CF (Mouse model) 2.93E−02 Development_PEDF signaling 2.93E−02 Immune response_Bacterial infections in normal airways 2.93E−02 Stem cells_Cooperation between Hedgehog, IGF-2 and HGF signaling pathways in medulloblastoma 3.06E−02 stem cells Immune response_Immunological synapse formation 3.20E−02 Stem cells_Muscle progenitor cell migration in hypaxial myogenesis 3.24E−02 Apoptosis and survival_Lymphotoxin-beta receptor signaling 3.24E−02 Immune response_Gastrin in inflammatory response 3.38E−02 Transcription_Transcription factor Tubby signaling pathways 3.50E−02 Stem cells_EGF-induced proliferation of Type C cells in SVZ of adult brain 3.51E−02 Normal and pathological TGF-beta-mediated regulation of cell proliferation 3.51E−02 Mucin expression in CF via TLRs, EGFR signaling pathways 3.63E−02 Immune response_Neurotensin-induced activation of IL-8 in colonocytes 3.64E−02 Signal transduction_JNK pathway 3.64E−02 Cytoskeleton remodeling_Neurofilaments 3.66E−02 Development_Thyroliberin signaling 3.87E−02 Transcription_PPAR Pathway 3.87E−02 Stem cells_Role of PKR1 and ILK in cardiac progenitor cells 4.00E−02 Apoptosis and survival_Role of CDK5 in neuronal death and survival 4.00E−02 Development_CNTF receptor signaling 4.00E−02 wtCFTR and deltaF508 traffic/Membrane expression (norm and CF) 4.00E−02 Chemotaxis_CXCR4 signaling pathway 4.00E−02 Neurophysiological process_Dopamine D2 receptor transactivation of PDGFR in CNS 4.26E−02 Immune response_Signaling pathway mediated by IL-6 and IL-1 4.91E−02 Development_FGF2-dependent induction of EMT 4.46E−04 Transcription_ChREBP regulation pathway 6.25E−04 Regulation of lipid metabolism_Insulin regulation of glycogen metabolism 2.76E−03 Transport_Macropinocytosis 9.84E−03 Regulation of CFTR activity (norm and CF) 7.82E−05 Cell adhesion_Chemokines and adhesion 2.69E−07 Development_TGF-beta-dependent induction of EMT via RhoA, PI3K and ILK. 1.13E−04 K-RAS signaling in lung cancer 6.72E−03 Cell adhesion_Alpha-4 integrins in cell migration and adhesion 3.71E−06 Cytoskeleton remodeling_Cytoskeleton remodeling 1.05E−09 Muscle contraction_Relaxin signaling pathway 8.94E−03 Apoptosis and survival_BAD phosphorylation 9.18E−04 IL-6 signaling in multiple myeloma 8.76E−04 Apoptosis and survival_Apoptotic TNF-family pathways 9.18E−04 Immune response_IL-2 activation and signaling pathway 3.17E−03 Dual role of BMP signaling in gastric cancer 3.50E−04 Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases 1.34E−09 Cell cycle_Initiation of mitosis 9.37E−03 Transcription_CREB pathway 1.35E−03 Signal transduction_PKA signaling 1.64E−05 Stem cells_Endothelial differentiation during embryonic development 3.25E−04 Cytoskeleton remodeling_TGF, WNT and cytoskeletal remodeling 1.88E−09 HBV-dependent NF-kB and PI3K/AKT pathways leading to HCC 8.76E−04 Translation_Regulation of translation initiation 6.27E−04 Cell cycle_Influence of Ras and Rho proteins on G1/S Transition 1.18E−04 Apoptosis and survival_Granzyme A signaling 1.35E−03

TABLE 12 Pathways Upregulated in Parous CD44+ Cells Relative to Nulliparous CD44+ Cells P-val in Pathway maps P CD44+ TTP metabolism   0.0000608 Resistance of pancreatic cancer cells to death receptor signaling 1.29E−04 Transcription_Assembly of RNA Polymerase II preinitiation complex on TATA-less promoters  0.000136 Development_PIP3 signaling in cardiac myocytes 3.38E−04 HCV-dependent regulation of RNA polymerases leading to HCC  0.00035 Stem cells_H3K9 demethylases in pluripotency maintenance of stem cells 4.62E−04 Inhibition of apoptosis in gastric cancer 6.32E−04 Cell cycle_Start of DNA replication in early S phase  0.00067 Apoptosis and survival_Caspase cascade  0.000816 Immune response_BCR pathway 9.79E−04 Immune response_ICOS pathway in T-helper cell 1.40E−03 Cell cycle_The metaphase checkpoint  0.00141 Inhibitory action of Lipoxins on neutrophil migration 1.46E−03 Cytoskeleton remodeling_Alpha-1A adrenergic receptor-dependent inhibition of PI3K 1.67E−03 DNA damage_NHEJ mechanisms of DSBs repair 1.67E−03 Regulation of metabolism_Triiodothyronine and Thyroxine signaling  0.00186 Cell cycle_Chromosome condensation in prometaphase 2.70E−03 Development_IGF-1 receptor signaling 2.77E−03 dCTP/dUTP metabolism 0.003  dGTP metabolism  0.00332 Inhibition of RUNX3 signaling in gastric cancer  0.00336 Apoptosis and survival_Beta-2 adrenergic receptor anti-apoptotic action  0.00412 Signal transduction_Activin A signaling regulation 4.38E−03 Stem cells_Fetal brown fat cell differentiation  0.00447 Immune response_CXCR4 signaling via second messenger 5.11E−03 dATP/dITP metabolism  0.00573 Signal transduction_PTEN pathway 5.97E−03 Microsatellite instability in gastric cancer  0.00601 Inhibition of TGF-beta signaling in gastric cancer 6.01E−03 Immune response_Regulation of T cell function by CTLA-4 6.82E−03 DNA damage_DNA-damage-induced responses  0.00747 Stem cells_Self-renewal of adult neural stem cells  0.00756 Regulation of degradation of deltaF508 CFTR in CF 8.44E−03 Transcription_Sin3 and NuRD in transcription regulation  0.00892 Blood coagulation_GPIb-IX-V-dependent platelet activation  0.00952 Transcription_Receptor-mediated HIF regulation 1.01E−02 Stem cells_Signaling pathways in embryonic hepatocyte maturation 1.05E−02 Apoptosis and survival_nAChR in apoptosis inhibition and cell cycle progression 1.15E−02 Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway 1.29E−02 DNA damage_Role of Brca1 and Brca2 in DNA repair 0.0133 Translation_IL-2 regulation of translation 0.0139 DNA damage_Inhibition of telomerase activity and cellular senescence 0.0139 DNA damage_Mismatch repair 0.0139 Neurophysiological process_Olfactory transduction 0.0139 Immune response_CD28 signaling 1.42E−02 Immune response_Role of DAP12 receptors in NK cells 0.0142 Immune response_PIP3 signaling in B lymphocytes 0.0144 Immune response_ETV3 affect on CSF1-promoted macrophage differentiation 0.0152 Blood coagulation_GPVI-dependent platelet activation 0.0157 Inhibition of tumor suppressive pathways in pancreatic cancer 1.65E−02 Transcription_Ligand-Dependent Transcription of Retinoid-Target genes 0.0196 Role of alpha-6/beta-4 integrins in carcinoma progression 0.0199 Development_Thrombopoietin-regulated cell processes 1.99E−02 Chemotaxis_Lipoxin inhibitory action on fMLP-induced neutrophil chemotaxis 2.20E−02 Development_EGFR signaling via PIP3 0.0226 G-protein signaling_S1P2 receptor signaling 0.0248 Stem cells_Differentiation of natural regulatory T cells 0.0248 Translation_Opioid receptors in regulation of translation 2.61E−02 Transport_RAB3 regulation pathway 0.0271 G-protein signaling_RAC1 in cellular process 0.0277 DNA damage_Nucleotide excision repair 0.0277 Immune response_Inhibitory action of lipoxins on superoxide production induced by IL-8 and 2.91E−02 Leukotriene B4 in neutrophils Inhibitory action of Lipoxins on Superoxide production in neutrophils 2.91E−02 wtCFTR and delta508-CFTR traffic/Generic schema (norm and CF) 0.0317 Apoptosis and survival_DNA-damage-induced apoptosis 0.0327 Apoptosis and survival_NGF signaling pathway 0.0341 Apoptosis and survival_APRIL and BAFF signaling 3.42E−02 Immune response_NFAT in immune response 0.0346 Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/IAP pathway 3.85E−02 Immune response_TCR and CD28 co-stimulation in activation of NF-kB 0.0414 Immune response_Innate immune response to RNA viral infection 4.33E−02 Immune response_IFN gamma signaling pathway 0.044  Immune response_CD16 signaling in NK cells 0.0472 Immune response_Delta-type opioid receptor signaling in T-cells 4.84E−02 Apoptosis and survival_p53-dependent apoptosis 0.0484 Stem cells_Role of growth factors in the maintenance of embryonic stem cell pluripotency 0.0129 Chemoresistance pathways mediated by constitutive activation of PI3K pathway and BCL-2 in 2.20E−05 small cell lung cancer Signal transduction_AKT signaling 2.74E−05 Immune response_Inhibitory action of Lipoxins on pro-inflammatory TNF-alpha signaling 4.18E−05 Apoptosis and survival_Cytoplasmic/mitochondrial transport of proapoptotic proteins Bid, Bmf and 1.61E−04 Bim Translation_Regulation of EIF4F activity 1.81E−04 PI3K signaling in gastric cancer 6.36E−04 Chemotaxis_Inhibitory action of lipoxins on IL-8- and Leukotriene B4-induced neutrophil migration 6.36E−04 Translation_Insulin regulation of translation 7.48E−04 Transcription_Role of Akt in hypoxia induced HIF1 activation 1.49E−03 Apoptosis and survival_Ceramides signaling pathway 1.96E−03 Apoptosis and survival_Role of IAP-proteins in apoptosis 3.16E−03 Proteolysis_Role of Parkin in the Ubiquitin-Proteasomal Pathway 5.01E−03 Anti-apoptotic action of Gastrin in pancreatic cancer 5.92E−03

TABLE 13 GeneGo Functional Enrichment Analysis by Protein Class for Differentially Expressed Genes in CD44+, CD24+, CS10+ and Stromal Breast Epithelial Cell Types Protein class Actual n R N Expected Ratio p-value z-score Protein class enriched in nulliparous CD44+ cells phosphatases 33 2078 230 22651 21.1 1.564 6.690E−03 2.732 ligands 67 2078 507 22651 46.51 1.44 1.524E−03 3.188 kinases 71 2078 650 22651 59.63 1.191 6.960E−02 1.567 transcription 101 2078 951 22651 87.24 1.158 6.627E−02 1.579 factors enzymes 286 2078 2693 22651 247.1 1.158 3.576E−03 2.77 proteases 57 2078 552 22651 50.64 1.126 1.896E−01 0.9493 receptors 97 2078 1492 22651 136.9 0.7087 6.932E−05 −3.7 other 1374 2078 15628 22651 1434 0.9584 1.705E−03 −2.972 Protein class enriched in nulliparous CD10+ cells proteases 59 1491 552 22651 36.34 1.624 1.665E−04 3.938 ligands 53 1491 507 22651 33.37 1.588 5.912E−04 3.555 enzymes 218 1491 2693 22651 177.3 1.23 5.826E−04 3.372 transcription 68 1491 951 22651 62.6 1.086 2.531E−01 0.7215 factors phosphatases 16 1491 230 22651 15.14 1.057 4.467E−01 0.2299 kinases 43 1491 650 22651 42.79 1.005 5.096E−01 0.03431 receptors 96 1491 1492 22651 98.21 0.9775 4.319E−01 −0.2388 other 946 1491 15628 22651 1029 0.9196 1.294E−06 −4.792 Protein class enriched in nulliparous CD24+ cells phosphatases 23 1273 230 22651 12.93 1.779 5.428E−03 2.899 enzymes 213 1273 2693 22651 151.3 1.407 9.672E−08 5.495 kinases 45 1273 650 22651 36.53 1.232 8.715E−02 1.464 transcription 51 1273 951 22651 53.45 0.9542 3.967E−01 −0.352 factors ligands 25 1273 507 22651 28.49 0.8774 2.859E−01 −0.6814 proteases 27 1273 552 22651 31.02 0.8703 2.598E−01 −0.7526 receptors 46 1273 1492 22651 83.85 0.5486 1.417E−06 −4.402 other 844 1273 15628 22651 878.3 0.9609 1.799E−02 −2.14 Protein class enriched in nulliparous stromal cells ligands 35 770 507 22651 17.24 2.031 6.543E−05 4.403 proteases 38 770 552 22651 18.76 2.025 3.424E−05 4.574 kinases 36 770 650 22651 22.1 1.629 2.994E−03 3.054 transcription 49 770 951 22651 32.33 1.516 2.625E−03 3.048 factors phosphatases 11 770 230 22651 7.819 1.407 1.619E−01 1.163 receptors 53 770 1492 22651 50.72 1.045 3.891E−01 0.3371 enzymes 69 770 2693 22651 91.55 0.7537 4.980E−03 −2.554 other 482 770 15628 22651 531.3 0.9073 7.001E−05 −3.905 Protein class enriched in parous CD44+ cells phosphatases 24 1820 230 22651 18.48 1.299 1.130E−01 1.346 enzymes 280 1820 2693 22651 216.4 1.294 1.994E−06 4.804 kinases 67 1820 650 22651 52.23 1.283 2.106E−02 2.163 transcription 88 1820 951 22651 76.41 1.152 9.018E−02 1.412 factors proteases 39 1820 552 22651 44.35 0.8793 2.234E−01 −0.8485 ligands 35 1820 507 22651 40.74 0.8592 1.949E−01 −0.948 receptors 76 1820 1492 22651 119.9 0.634 3.035E−06 −4.324 other 1215 1820 15628 22651 1256 0.9676 1.720E−02 −2.151 Protein class enriched in parous CD10+ cells enzymes 241 1721 2693 22651 204.6 1.178 3.179E−03 2.819 kinases 58 1721 650 22651 49.39 1.174 1.131E−01 1.294 ligands 41 1721 507 22651 38.52 1.064 3.611E−01 0.4202 phosphatases 17 1721 230 22651 17.48 0.9728 5.164E−01 −0.1189 transcription 65 1721 951 22651 72.26 0.8996 2.004E−01 −0.9072 factors proteases 33 1721 552 22651 41.94 0.7868 8.152E−02 −1.454 receptors 78 1721 1492 22651 113.4 0.6881 1.122E−04 −3.575 other 1193 1721 15628 22651 1187 1.005 3.921E−01 0.3036 Protein class enriched in parous CD24+ cells phosphatases 16 1173 230 22651 11.91 1.343 1.422E−01 1.223 kinases 42 1173 650 22651 33.66 1.248 8.280E−02 1.498 enzymes 170 1173 2693 22651 139.5 1.219 3.280E−03 2.829 transcription 58 1173 951 22651 49.25 1.178 1.104E−01 1.308 factors ligands 28 1173 507 22651 26.26 1.066 3.900E−01 0.3536 proteases 28 1173 552 22651 28.59 0.9795 5.044E−01 −0.1139 receptors 54 1173 1492 22651 77.26 0.6989 2.041E−03 −2.812 other 780 1173 15628 22651 809.3 0.9638 3.152E−02 −1.9 Protein class enriched in parous stromal cells enzymes 228 950 2693 22651 112.9 2.019 1.785E−26 11.78 kinases 35 950 650 22651 27.26 1.284 7.908E−02 1.536 phosphatases 9 950 230 22651 9.646 0.933 5.007E−01 −0.2137 ligands 12 950 507 22651 21.26 0.5643 1.865E−02 −2.076 proteases 13 950 552 22651 23.15 0.5615 1.370E−02 −2.182 transcription 22 950 951 22651 39.89 0.5516 1.014E−03 −2.956 factors receptors 29 950 1492 22651 62.58 0.4634 5.878E−07 −4.487 other 603 950 15628 22651 655.5 0.92 1.188E−04 −3.759 Protein class enrichment for promoter hypermethylation in nulliparous CD44+ cells kinases 37 838 650 22651 24.05 1.539 6.593E−03 2.731 transcription 54 838 951 22651 35.18 1.535 1.240E−03 3.303 factors enzymes 134 838 2693 22651 99.63 1.345 1.970E−04 3.738 proteases 25 838 552 22651 20.42 1.224 1.745E−01 1.045 ligands 20 838 507 22651 18.76 1.066 4.165E−01 0.2958 phosphatases 9 838 230 22651 8.509 1.058 4.798E−01 0.1724 receptors 40 838 1492 22651 55.2 0.7247 1.541E−02 −2.157 other 523 838 15628 22651 578.2 0.9046 2.087E−05 −4.199 Protein class enrichment for promoter hypermethylation in nulliparous CD44+ cells transcription 32 290 951 22651 12.18 2.628 6.665E−07 5.842 factors ligands 10 290 507 22651 6.491 1.541 1.180E−01 1.402 proteases 9 290 552 22651 7.067 1.273 2.774E−01 0.7408 kinases 10 290 650 22651 8.322 1.202 3.222E−01 0.594 enzymes 39 290 2693 22651 34.48 1.131 2.282E−01 0.8256 receptors 20 290 1492 22651 19.1 1.047 4.490E−01 0.2139 phosphatases 2 290 230 22651 2.945 0.6792 4.332E−01 −0.5569 other 170 290 15628 22651 200.1 0.8496 1.099E−04 −3.844 Protein class enrichment for genebody hypermethylation in nulliparous CD44+ cells transcription 31 249 951 22651 10.45 2.965 6.726E−08 6.528 factors phosphatases 4 249 230 22651 2.528 1.582 2.474E−01 0.9354 receptors 18 249 1492 22651 16.4 1.097 3.762E−01 0.4107 ligands 6 249 507 22651 5.573 1.077 4.852E−01 0.1838 kinases 6 249 650 22651 7.145 0.8397 4.249E−01 −0.4372 enzymes 21 249 2693 22651 29.6 0.7094 5.047E−02 −1.694 proteases 4 249 552 22651 6.068 0.6592 2.712E−01 −0.8547 other 160 249 15628 22651 171.8 0.9313 6.111E−02 −1.625 Protein class enrichment for genebody hypermethylation in parous CD44+ cells transcription 20 170 951 22651 7.137 2.802 3.207E−05 4.937 factors phosphatases 4 170 230 22651 1.726 2.317 9.542E−02 1.746 kinases 11 170 650 22651 4.878 2.255 1.018E−02 2.823 proteases 5 170 552 22651 4.143 1.207 3.995E−01 0.4279 enzymes 21 170 2693 22651 20.21 1.039 4.608E−01 0.1876 receptors 9 170 1492 22651 11.2 0.8037 3.107E−01 −0.6821 ligands 3 170 507 22651 3.805 0.7884 4.700E−01 −0.419 other 97 170 15628 22651 117.3 0.827 6.559E−04 −3.377

The analysis was further focused on CD44+ cells, which showed the most pronounced differences between parous and nulliparous states. Pathways highly active in nulliparous samples are related to major developmental and tumorigenic pathways including cytoskeleton remodeling, chemokines and cell adhesion, and WNT signaling (FIG. 13 and Table 10), whereas pathways more active in parous samples include PI3K/AKT signaling and apoptosis (FIG. 14 and Table 10). Importantly, the highest scored pathway for genes highly expressed in nulliparous samples is four orders of magnitude more statistically significant than those for the genes highly expressed in parous samples, suggesting that downregulation of protumorigenic developmental pathways is a prominent feature of CD44+ cells from parous women. Interactome analysis also demonstrated a much larger number of overconnected proteins in nulliparous than in parous state in all four cell types, but particularly in CD44+ cells (FIG. 12 ). As the relative number of interactions (connectivity) is directly related to the functional activity of the dataset [Nikolsky, Y., et al. (2008) Cancer Res 68, 9532-9540], this result suggested that parous cells are overall substantially less active than nulliparous ones.

Because pregnancy-induced protection against breast cancer is also observed in rodents, it was investigated whether pathways altered by parity are conserved across species. Pathways in CD44+ cells were compared to that generated based on genes differentially expressed between virgin and parous rats [Blakely et al., 2006, supra; D'Cruz, C. M., and Chodosh, L. A. (2006) Cancer Res 66, 6421-6431]. Significant overlap was found between pathways highly active in nulliparous and virgin samples (thus, downregulated in parous), but almost nothing in common was found among those highly active in parous tissues. The top ranked pathways were all related to cytoskeleton remodeling and cell adhesion, known to be highly relevant in stem cells (FIG. 15A and FIG. 15B). Thus, pregnancy appears to induce similar alterations in the mammary epithelium regardless of species. A network built of the common pathways included a complete NOTCH pathway (including NOTCH1 (GenBank Accession no., AB209873, AF308602, AL592301, BC013208), NOTCH1-NICD, ADAM17 (GenBank Accession no., BM725368, BQ186514), gamma secretase complex (PSENEN, GenBank Accession no., AF220053, BQ222622), APH1A (GenBank Accession Nos. BC020590, BI760743, DC365601), and APH1B (GenBank Accession Nos. AC016207, AI693802)), IGF1 (GenBank Accession Nos. AB209184, AC010202), EGF (GenBank Accession No. AC004050, AC005509), CD44 (GenBank Accession No. BC004372), CD9 (GenBank Accession Nos. AI003581, BG291377), and ITGB1 (GenBank Accession Nos. AI261443, BM973433, BX537407) as “triggers” (ligands and receptors), c-Src (GenBank Accession Nos. AF272982, BC051270), PKC (GenBank Accession No. NM_212535), and FAK (GenBank Accession Nos. AB209083, AK304356) as major signaling kinases, and c-Jun (GenBank Accession Nos. BC002646, BC009874), p53 (GenBank Accession No. AK223026, DA453049), SNAIL1 (GenBank Accession Nos. BC012910, DA972913), and LEF1 (GenBank Accession Nos. AC097067, AC118062) as transcription factors.

Example 4: Cell Type-Specific Epigenetic Patterns Related to Parity and their Functional Relevance

This example demonstrates that parity has a more pronounced long-term effect on DNA methylation than on H3 lysine 27 trimethylation (K27) patterns.

Reduction of breast cancer risk in postmenopausal women conferred by full-term pregnancy in early adulthood implies the induction of long-lasting changes such as alterations in cell type-specific epigenetic patterns. To investigate this hypothesis, the comprehensive DNA methylation and K27 profiles of CD24+ and CD44+ cells from nulliparous and parous women were analyzed using MSDKseq applied to high-throughput sequencing and ChlPseq, respectively. The data are summarized in Tables 14-17, below.

Comparison of MSDKseq libraries of nulliparous and parous samples within each cell type showed a higher number of significantly (p<0.05) differentially methylated regions (DMRs) in CD44+ cells and, in both cell types, more DMRs were hypermethylated in nulliparous than in parous cells (FIG. 16 and Table 14, below).

To validate differences in DNA methylation in additional samples and by other methods, quantitative methylation-specific PCR (qMSP) analyses of selected genes were performed using CD44+ cells from multiple nulliparous and parous cases. Despite some interpersonal variability, statistically significant differences were detected between nulliparous and parous groups that overall correlated with MSDKseq data (FIG. 6 ).

In Table 14, genes with DMR (hypermethylated in parous or nulliparous samples) in promoter region or genebody in CD44+ cells are listed. DMR pattern (hypermethylated in which sample in which region), gene symbol, RefSeq ID, gene description, chromosomal location, log 10 p-value (calculated by Poisson margin model), log ratio of averaged nulliparous and parous MSDK-tag counts, scaled MSDK-tag counts, chromosomal position of BssHII recognition sites, and distance between BssHII sites and TSS (plus and minus indicate downstream and upstream of TSS, respectively) are shown. The log 10 p-value and log ratio have a positive or negative sign which indicates DMR is hypermethylated in parous or nulliparous, respectively.

Global associations between differential gene expression and presence of DMRs were analyzed in CD44+ and CD24+ cells, but significant associations were not found, potentially due to the complex relationship between DNA methylation and transcript levels, as DNA methylation can both positively (e.g., in gene body) and negatively (e.g., in promoters) regulate gene expression, depending on the location relative to transcription start site.

The data from the analyses are summarized in Table 15 and Table 16, below, which list genes that are differentially methylated between nulliparous and parous CD44+ and CD24+ cells, respectively, along with SAGEseq, ChlPseq and MSDKseq data for the listed genes. Significant differences in genes enriched for H3K27mc3 mark were not detected in CD44+ or CD24+ cells from nulliparous and parous samples. However, genes highly expressed in CD44+ or CD24+ cells from nulliparous women were not K27-enriched in either parous or nulliparous cases, implying the potential lack of their regulation by the PRC2 complex that establishes this histone mark (see, Tables 15 and 16).

Overall it appears that parity may have a more pronounced long-term effect on DNA methylation than on K27 patterns.

To investigate pathways affected by parity-related epigenetic alterations, pathways enriched by genes associated with gene body or promoter DMRs were analyzed in CD44+ cells from nulliparous and parous samples. Very little overlap was found among the four distinct categories (FIG. 17 ). Relatively few pathways were significantly enriched in both expression and methylation data and most of these were related to development, TGFβ and WNT signaling.

The fraction of transcription factors (TFs) among differentially methylated genes was 2-3 fold higher than expected and what was observed among differentially expressed genes, implying that promoter methylation might be a preferred control mechanism of their expression. Similar to the expression data, DMRs in nulliparous samples had higher numbers of overconnected objects than in parous ones. Gene body DMRs in CD44+ nulliparous cells had the highest number of overconnected objects and transcription factors represented a significant fraction of overconnected objects in promoter hypermethylated DMRs in CD44+ nulliparous cells. Further, Table 17 lists enriched GeneGo pathway maps for differentially methylated regions (DMRs) in promoter (−5 to 2 kb) and gene body (+2 kb to end) in CD44+ cells from human breast epithelium. The table contains canonical pathway maps with p-values (<0.05) indicating significance of enrichment for differentially methylated genes (hypo/hyper methylated) in CD44+ progenitor-enriched cells from nulliparous or parous cases.

TABLE 14 Comprehensive DNA Methylation and K27 Profiles of CD44+ Nulliparous and Parous Breast Epithelial Cells log10 Methylation Location Symbol Accession Official Full Name Chromosome pval. parous promoter HECTD1 NM_015382 HECT domain containing 1 14q12 4.2 parous promoter CDX2 NM_001265 caudal type homeobox 2 13q12.2 −4.3 parous promoter CDX2 NM_001265 caudal type homeobox 2 13q12.2 5.6 parous promoter CLMN NM_024734 calmin (calponin-like, transmembrane) 14q32.2 16.9 parous promoter C13orf18 NM_025113 chromosome 13 open reading frame 18 13q14.11 19.5 parous promoter PCDHGB1 NM_032095 protocadherin gamma subfamily B, 1 5q31 9.6 parous promoter UBE2Q2 NM_173469 ubiquitin-conjugating enzyme E2Q family member 2 15q24.2 4.7 parous promoter MMP23B NM_006983 matrix metallopeptidase 23B 1p36.3 4 parous promoter PCDHGB5 NM_032099 protocadherin gamma subfamily B, 5 5q31 38 parous promoter UBAC1 NM_016172 UBA domain containing 1 9q34.3 3.5 parous promoter NKX2-6 NM_001136271 NK2 transcription factor related, locus 6 (Drosophila) 8p21.2 128.4 parous promoter GABRB2 NM_021911 gamma-aminobutyric add (GABA) A receptor, beta 2 5q34 3.7 parous promoter SLC30A3 NM_003459 solute carrier family 30 (zinc transporter), member 3 2p23.3 2.7 parous promoter MGC3771 NR_024167 NA NA 3.5 parous promoter SMG6 NM_017575 Smg-6 homolog, nonsense mediated mRNA 17p13.3 92.9 decay factor (C. elegans) parous promoter SMG6 NM_017575 Smg-6 homolog, nonsense mediated mRNA 17p13.3 92.9 decay factor (C. elegans) parous promoter EHD1 NM_006795 EH-domain containing 1 11q13 3.1 parous promoter ZNF146 NM_007145 zinc finger protein 146 19q13.1 8.6 parous promoter C11orf35 NM_173573 chromosome 11 open reading frame 35 11 2.3 parous promoter CCDC96 NM_153376 coiled-coil domain containing 96 4p16.1 3.8 parous promoter ADAMTS9 NM_182920 ADAM metallopeptidase with thrombospondin 3p14.1 3.4 type 1 motif, 9 parous promoter DHRS3 NM_004753 dehydrogenase/reductase (SDR family) member 3 1p36.1 2.7 parous promoter DGCR6 NM_005675 DiGeorge syndrome critical region gene 6 22q11.21 17.8 parous promoter LOC113230 NR_024282 NA NA 2.1 parous promoter DLEU2 NR_002612 deleted in lymphocytic leukemia 2 (non-protein coding) 13q14 10.3 parous promoter DMTF1 NM_021145 cydin D binding myb-like transcription factor 1 7q21 11.1 parous promoter IRX3 NM_024336 iroquois homeobox 3 16q12.2 7.7 parous promoter IREB2 NM_004136 iron-responsive element binding protein 2 15 11.3 parous promoter CBLC NM_001130852 Cas-Br-M (murine) ecotropic retroviral 19q13.2 2.5 transforming sequence c parous promoter ZNF444 NM_018337 zinc finger protein 444 19q13.43 24.7 parous promoter STK11 NM_000455 serine/threonine kinase 11 19p13.3 16.6 parous promoter NF1 NM_000267 neurofibromin 1 17q11.2 24.8 parous promoter SIRPA NM_001040022 signal-regulatory protein alpha 20p13 96 parous promoter FAM76B NM_144664 family with sequence similarity 76, member B 11q21 23.5 parous promoter ALOXE3 NM_021628 arachidonate lipoxygenase 3 17p13.1 214.5 parous promoter COG1 NM_018714 component of oligomeric golgi complex 1 17q25.1 2.5 parous promoter BCAT2 NM_001190 branched chain aminotransferase 2, mitochondrial 19 36.9 parous promoter EVX2 NM_001080458 even-skipped homeobox 2 2q31.1 13.6 parous promoter WDR21C NM_152418 NA NA 29.2 parous promoter PMS2 NM_000535 PMS2 postmeiotic segregation 7p22.1 2.6 increased 2 (S. cerevisiae) parous promoter LOC285548 NR_015450 NA NA 2.4 parous promoter NKX6-2 NM_177400 NK6 homeobox 2 10q26.3 13.3 parous promoter PDE8A NM_002605 phosphodiesterase 8A 15q25.3 27.2 parous promoter ADRA1A NM_033303 adrenergic, alpha-1A-, receptor 8p21.2 3.6 parous promoter ADRA1A NM_033303 adrenergic, alpha-1A-, receptor 8p21.2 2 parous promoter SYNCRIP NM_006372 synaptotagmin binding, cytoplasmic 6q14-q15 10.2 RNA interacting protein parous promoter KCTD11 NM_001002914 potassium channel tetramerisation 17p13.2 110.4 domain containing 11 parous promoter C19orf57 NM_024323 chromosome 19 open reading frame 57 19p13.12 2.6 parous promoter LRP4 NM_002334 low density lipoprotein receptor-related protein 4 11p11.2 2.1 parous promoter HERV-FRD NM_207582 NA NA 2.6 parous promoter AKT1 NM_005163 v-akt murine thymoma viral oncogene homolog 1 14q32.32-q32.33 16.9 parous promoter ZNF175 NM_007147 zinc finger protein 175 19q13.4 17.9 parous promoter ROBO3 NM_022370 roundabout, axon guidance receptor, 11q24 2.5 homolog 3 (Drosophila) parous promoter GM2A NM_000405 GM2 ganglioside activator 5 4.5 parous promoter FA2H NM_024306 fatty add 2-hydroxylase 16q23 107.5 parous promoter SYT6 NM_205848 synaptotagmin VI 1p13.1 16.4 parous promoter HBP1 NM_012257 HMG-box transcription factor 1 7q22-q31 2.4 parous promoter CEP76 NM_024899 centrosomal protein 76 kDa 18p11.21 2.3 parous promoter CSMD1 NM_033225 CUB and Sushi multiple domains 1 8p23.2 18.1 parous promoter RAB43 NM_198490 RAB43, member RAS oncogene family 3q21.3 16.2 parous promoter YEATS4 NM_006530 YEATS domain containing 4 12q13-q15 3.3 parous promoter FST NM_013409 follistatin 5q11.2 16.3 parous promoter ZNF565 NM_001042474 zinc finger protein 565 19 8.6 parous promoter CSRP2 NM_001321 cysteine and glycine-rich protein 2 12q21.1 4 parous promoter LOC653319 NM_001040715 NA NA 25.5 parous promoter MAL NM_022439 mal, T-cell differentiation protein 2q11.1 19 parous promoter HHIP NM_022475 hedgehog interacting protein 4q31.21-q31.3 6.8 parous promoter SNX3 NM_003795 sorting nexin 3 6q21 −2.9 parous promoter SNX3 NM_003795 sorting nexin 3 6q21 5.9 parous promoter MMP15 NM_002428 matrix metallopeptidase 15 (membrane-inserted) 16q13 2.8 parous promoter ACSL1 NM_001995 acyl-CoA synthetase long-chain family member 1 4q35 3.4 parous promoter MMP23A NR_002946 matrix metallopeptidase 23A (pseudogene) 1p36.3 4 parous promoter VPS11 NM_021729 vacuolar protein sorting 11 homolog (S. cerevisiae) 11q23 3.1 parous promoter ANO1 NM_018043 anoctamin 1, calcium activated chloride channel 11q13.2 7.9 parous promoter RASSF7 NM_003475 Ras association (RalGDS/AF-6) domain 11p15.5 2.3 family (N-terminal) member 7 parous promoter FMN2 NM_020066 formin 2 1q43 6.8 parous promoter PDGFC NM_016205 platelet denved growth factor C 4q32 12.9 parous promoter CC2D1A NM_017721 cotled-coil and C2 domain containing 1A 19p13.12 2.6 parous promoter KREMEN2 NM_024507 kringle containing transmembrane protein 2 16p13.11 20.3 parous promoter KLHDC5 NM_020782 kelch domain containing 5 12p11.22 3.7 parous promoter CHKA NM_001277 choline kinase alpha 11q13.1 7.2 parous promoter CHKB NM_152253 choline kinase beta 22q13.33 14.5 parous promoter PPM1G NM_177983 protein phosphatase 1G (formerly 2C), 2p23.3 3.7 magnesium-dependent, gamma isoform parous promoter CYGB NM_134268 cytoglobin 17q25 10.4 parous promoter CHCHD6 NM_032343 coiled-coil-helix-coiled-coil-helix domain 3q21.3 2.6 containing 6 parous promoter ABCF2 NM_005692 ATP-binding cassette, sub-family 7q35-q36 5.8 F (GCN20), member 2 parous promoter USP45 NM_001080481 ubiquitin specific peptidase 45 6q16.2 4.1 parous promoter SCO NM_005063 stearoyl-CoA desaturase (delta-9-desaturase) 10q23-q24 41.1 parous promoter TADA2B NM_152293 NA NA 3.8 parous promoter JUN NM_002228 jun oncogene 1p32-p31 2.1 parous promoter TRPA1 NM_007332 transient receptor potential cation channel, 8q13 37 subfamily A, member 1 parous promoter UNC5B NM_170744 unc-5 homolog B (C. elegans) 10q22.2 −3.3 parous promoter UNC5B NM_170744 unc-5 homolog B (C. elegans) 10q22.2 15.6 parous promoter NPC1 NM_000271 Niemann-Pick disease, type C1 18q11-q12 64.8 parous promoter DGCR6L NM_033257 DiGeorge syndrome critical region 22q11 8.6 parous promoter CDC42BPA NM_003607 CDC42 binding protein kinase alpha (DMPK-like) 1q42.11 20 parous promoter PSMG2 NM_020232 proteasome (prosome, macropain) 18p11.21 2.3 assembly chaperone 2 parous promoter VSX2 NM_182894 visual system homeobox 2 14q24.3 2.8 parous promoter VSX2 NM_182894 visual system homeobox 2 14q24.3 95.3 parous promoter CRMP1 NM_001313 collapsin response mediator protein 1 4p16.1 4.1 parous promoter SNX30 NM_001012994 sorting nexin family member 30 9q33.1 6.3 parous promoter OSMR NM_003999 oncostatin M receptor 5p13.2 25.3 parous promoter TRPM2 NM_003307 transient receptor potential cation channel, 21q22.3 7.2 subfamily M, member 2 parous promoter GPR137 NM_020155 G protein-coupled receptor 137 11cen-q22.3 7.9 parous promoter HOXB8 NM_024016 homeobox B8 17q21.32 32.8 parous promoter PRKCB NM_212535 protein kinase C, beta 16p12 9.3 parous promoter GRP NM_002091 gastrin-releasing peptide 18q21.1-q21.32 13.5 parous promoter HOXB2 NM_002145 homeobox B2 17q21.32 14 parous promoter FIBCD1 NM_032843 fibrinogen C domain containing 1 9q34.2 −2.1 parous promoter FIBCD1 NM_032843 fibrinogen C domain containing 1 9q34.2 19.8 parous promoter TUBB3 NM_006086 tubulin, beta 3 16q24.3 28.9 parous promoter TMEM95 NM_198154 transmembrane protein 95 17p13.1 110.4 parous promoter RIMKLA NM_173642 ribosomal modification protein rimK- 1p34.2 5.8 like family member A parous promoter HIST1H2BF NM_003522 histone cluster 1, H2bf 6p22.1 3.2 parous promoter PCDHGA9 NM_032089 protocadherin gamma subfamily A, 9 5q31 38 parous promoter PCDHGA9 NM_032089 protocadherin gamma subfamily A, 9 5q31 −3.5 parous promoter DDN NM_015086 dendrin 12q13 3.9 parous promoter PAPD5 NM_001040284 PAP associated domain containing 5 16q12.1 3 parous promoter BRF2 NM_018310 BRF2, subunit of RNA polymerase III transcription 8p11.23 2.5 initiation factor BRF1-like parous promoter AMN1 NM_001113402 antagonist of mitotic exit network 12p11.21 11.7 1 homolog (S. cerevisiae) parous promoter HOXB5 NM_002147 homeobox B5 17q21.32 −2.9 parous promoter HOXB5 NM_002147 homeobox B5 17q21.32 13.8 parous promoter FGF2 NM_002006 fibroblast growth factor 2 (basic) 4q26 2.7 parous promoter BCAR3 NM_003567 breast cancer anti-estrogen resistance 3 1p22.1 2.1 parous promoter CDC5L NM_001253 CDC5 cell division cyde 5-like (S. pombe) 6p 3.8 parous promoter ZBTB42 NM_001137601 zinc finger and BTB domain containing 42 14q32.33 16.9 parous promoter ETV5 NM_004454 ets variant 5 3q28 2.1 parous promoter SEMA5B NM_001031702 sema domain, seven thrombospondin repeats 3q21.1 35.9 (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B parous promoter RNASEH2C NM_032193 ribonuclease H2, subunit C 11q13.1 8.8 parous promoter DSCR6 NM_018962 Down syndrome critical region gene 6 21q22.2 12 parous promoter RAN NM_006325 RAN, member RAS oncogene family 12 254.2 parous promoter ELOVL2 NM_017770 elongation of very long chain fatty acids 6p24.1 6.9 (FEN1/Elo2, SUR4/Elo3, yeast)-like 2 parous promoter ELOVL3 NM_152310 elongation of very long chain fatty acids 10q24 14.4 (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 parous promoter SERBP1 NM_001018067 SERPINE1 mRNA binding protein 1 1p31 205.7 parous promoter EFCAB1 NM_024593 EF-hand calcium binding domain 1 8q11.21 3.5 parous promoter ISLR2 NM_001130136 immunoglobulin superfamily containing 15q24.1 3.9 leucine-rich repeat 2 parous promoter ISLR2 NM_001130136 immunoglobulin superfamily 15q24.1 −2.4 containing leucine-rich repeat 2 parous promoter TRIM7 NM_203297 tripartite motif-containing 7 5q35.3 4.7 parous promoter HES7 NM_032580 hairy and enhancer of split 7 (Drosophila) 17p13.1 214.5 parous promoter LOC440396 NR_002943 NA NA 92.9 parous promoter VBP1 NM_003372 von Hippel-Lindau binding protein 1 Xq28 3.9 parous promoter CHAD NM_001267 chondroadherin 17q21.33 9.2 parous promoter CAPZB NM_004930 capping protein (actin filament) muscle Z-line, beta 1p36.1 7.4 parous promoter CTDP1 NM_004715 CTD (carboxy-terminal domain, RNA polymerase II, 18q23 3.5 polypeptide A) phosphatase, subunit 1 parous promoter KIAA0586 NM_014749 KIAA0586 14q23.1 6.4 parous promoter FBXO2 NM_012168 F-box protein 2 1p36.21 28.8 parous promoter DMRT3 NM_021240 doublesex and mab-3 related transcription factor 3 9p24.3 113.6 parous promoter ADAMTS15 NM_139055 ADAM metallopeptidase with 11q25 34.7 thrombospondin type 1 motif, 15 parous promoter IFI27L1 NM_145249 interferon, alpha-inducible protein 27-like 1 14q32.13 4.2 parous promoter TBX4 NM_018488 T-box4 17q21-q22 5.1 parous promoter COX7A1 NM_001864 cytochrome c oxidase subunit 19q13.1 3.1 Vila polypeptide 1 (muscle) parous promoter FAM62C NM_031913 NA NA −2.5 parous promoter FAM62C NM_031913 NA NA 44.8 parous promoter PION NM_017439 pigeon homolog (Drosophila) 7q11.23 15.4 parous promoter GPR143 NM_000273 G protein-coupled receptor 143 Xp22.3 46.4 parous promoter CPXM2 NM_198148 carboxypeptidase X (M14 family), member 2 10q26 20.5 parous promoter TPM2 NM_213674 tropomyosin 2 (beta) 9p13 3.1 parous promoter TPM1 NM_001018006 tropomyosin 1 (alpha) 15q22.1 103.6 parous promoter IQCH NM_001031715 IQ motif containing H 15q23 4.8 parous promoter PCDHGA4 NM_032053 protocadherin gamma subfamily A, 4 5q31 9.6 parous promoter ACLY NM_001096 ATP citrate lyase 17q21.2 3.2 parous promoter OSBPL10 NM_017784 oxysterol binding protein-like 10 3p23 3.4 parous promoter AP3D1 NM_001077523 adaptor-related protein complex 3, delta 1 subunit 19p13.3 5.9 parous promoter MORF4L2 NM_012286 mortality factor 4 like 2 Xq22 6.8 parous promoter FBXO44 NM_183412 F-box protein 44 1p36.21 28.8 parous promoter BEND4 NM_207406 BEN domain containing 4 4p13 4.8 parous promoter CGB8 NM_033183 chorionic gonadotropin, beta polypeptide 8 19q13.32 3 parous promoter LRFN5 NM_152447 leucine rich repeat and fibronectn 14q21.1 5.7 type III domain containing 5 parous promoter EFNA4 NM_182690 ephrin-A4 1q21-q22 50.5 parous promoter PAQR4 NM_152341 progestin and adipoQ receptor family member IV 16p13 20.3 parous promoter SRM NM_003132 spermidine synthase 1p36-p22 3.4 parous promoter SRR NM_021947 serine racemase 17p13 92.9 parous promoter SALL4 NM_020436 sal-like 4 (Drosophila) 20q13.2 5.7 parous promoter HOXB7 NM_004502 homeobox B7 17q21.32 43 parous promoter FLJ11506 NM_024666 NA NA 4.8 parous promoter MERTK NM_006343 c-mer proto-oncogene tyrosine kinase 2q14.1 −10 parous promoter MERTK NM_006343 c-mer proto-oncogene tyrosine kinase 2q14.1 6.2 parous promoter GP5 NM_004488 glycoprotein V (platelet) 3q29 7.5 parous promoter HAP1 NM_001079871 huntingtin-associated protein 1 17q21.2-q21.3 54.3 parous promoter LEF1 NM_001130713 lymphoid enhancer-binding factor 1 4q23-q25 2.8 parous promoter ADM NM_001124 adrenomedullin 11 2.3 parous promoter OLIG2 NM_005806 oligodendrocyte lineage transcription factor 2 21q22.11 2.6 parous promoter CSGLCA-T NM_019015 NA NA 5.8 parous promoter VSX1 NM_014588 visual system homeobox 1 20p11.21 −4.8 parous promoter VSX1 NM_014588 visual system homeobox 1 20p11.21 3.2 parous promoter TRAFD1 NM_006700 TRAF-type zinc finger domain containing 1 12q 36.8 parous promoter SCARF2 NM_153334 scavenger receptor class F, member 2 22q11.21 10.1 parous promoter B3GALNT1 NM_033168 beta-1,3-N-acetylgalactosaminyl transferase 1 3q25 3 (globoside blood group) parous promoter RAB11FIP4 NM_032932 RAB11 family interacting protein 4 (class II) 17q11.2 13.4 parous promoter NTN1 NM_004822 netrin 1 17p13-p12 8.4 parous promoter NTN4 NM_021229 netrin 4 12q22 6 parous promoter INSR NM_001079817 insulin receptor 19p13.3-p13.2 4.8 parous promoter BAD NM_032989 BCL2-associated agonist of cell death 11q13.1 7.9 parous promoter TCF7L1 NM_031283 transcription factor 7-like 1 2p11.2 12.1 (T-cell specific, HMG-box) parous promoter C9orf75 NM_173691 chromosome 9 open reading frame 75 9q34.3 4.8 parous promoter C3orf45 NM_153215 chromosome 3 open reading frame 45 3p21.31 6.2 parous promoter NKX3-2 NM_001189 NK3 homeobox 2 4p16.3 −2 parous promoter NKX3-2 NM_001189 NK3 homeobox 2 4p16.3 2.4 parous promoter OXTR NM_000916 oxytocin receptor 3p25 5.6 parous promoter SOCS5 NM_014011 suppressor of cytokine signaling 5 2p21 36.1 parous promoter AMIGO2 NM_181847 adhesion molecule with Ig-like domain 2 12q13.11 5.5 parous promoter LDLRAP1 NM_015627 low density lipoprotein receptor adaptor protein 1 1p36-p35 3.8 parous promoter HMX2 NM_005519 H6 family homeobox 2 10q26.13 2.5 parous promoter PHF10 NM_018288 PHD finger protein 10 6q27 3.2 parous promoter TRIM71 NM_001039111 tripartite motif-containing 71 3p22.3 30.8 parous promoter AKR1CL2 NM_001040177 NA NA 2.4 parous promoter TCEB3 NM_003198 transcription elongation factor B (SIII), 1p36.1 6.8 polypeptide 3 (110 kDa, elongin A) parous promoter CEP57 NM_014679 centrosomal protein 57 kDa 11q21 23.5 parous promoter FLJ40125 NM_001080401 NA NA 4.7 parous promoter C21orf66 NM_016631 chromosome 21 open reading frame 66 21q22.11 6 parous promoter C17orf91 NM_032895 chromosome 17 open reading frame 91 17p13.3 28.7 parous promoter TIMM9 NM_012460 translocase of inner mitochondrial 14q22.3-q24 6.4 membrane 9 homolog (yeast) parous promoter SLC33A1 NM_004733 solute carrier family 33 3q 2.3 (acetyl-CoA transporter), member 1 parous promoter MRPS17 NM_015969 mitochondrial ribosomal protein S17 7p11-q11.21 7.6 parous promoter KANK4 NM_181712 KN motif and ankyrin repeat domains 4 1p31.3 9 parous promoter SOX8 NM_014587 SRY (sex determining region Y)-box 8 16p13.3 2.9 parous promoter SOX9 NM_000346 SRY (sex determining region Y)-box 9 17q23 3.6 parous promoter MYLPF NM_013292 myosin light chain, phosphorylatable, 16p11.2 5 fast skeletal muscle parous promoter HIST1H2AD NM_021065 histone cluster 1, H2ad 6p22.1 3.2 parous promoter MOXD1 NM_015529 monooxygenase, DBH-like 1 6q23.2 3 parous promoter GALNTL1 NM_020692 UDP-N-acetyl-alpha-D-galactosamine:polypeptide 14q24.1 3.4 N-acetylgalactosaminyltransferase-like 1 parous promoter SMARCA2 NM_139045 SWI/SNF related, matnx associated, 9p24.3 2.9 actin dependent regulator of chromatin, subfamily a, member 2 parous promoter FIBIN NM_203371 fin bud initiation factor homolog (zebrafish) 11p14.2 2.6 parous promoter CPSF1 NM_013291 cleavage and potyadenylation specific factor 1, 160 kDa 8q24 −7.8 parous promoter CPSF1 NM_013291 cleavage and potyadenylation specific factor 1, 160 kDa 8q24 2.6 parous promoter FAM83D NM_030919 family with sequence similarity 83, member D 20 2.7 parous promoter SERTAD3 NM_013368 SERTA domain containing 3 19q13.2 6.3 parous promoter ASAH1 NM_177924 N-acylsphingosine amidohydrolase 8p22 7.2 (add ceramidase) 1 parous promoter RAD54L NM_003579 RAD54-like (S. cerevisiae) 1p32 12.2 parous promoter ZMYM5 NM_001039649 zinc finger, MYM-type 5 13q12 6.3 parous promoter PTHLH NM_198966 parathyroid hormone-like hormone 12p12.1-p11.2 4.8 parous promoter ALX4 NM_021926 ALX homeobox 4 11p11.2 23.9 parous promoter FOXRED2 NM_024955 FAD-dependent oxidoreductase domain containing 2 22q12.3 75.8 parous promoter GAL NM_015973 galanin prepropeptide 11q13.2 13.9 parous promoter DOK6 NM_152721 docking protein 6 18q22.2 3.2 parous promoter KCNS1 NM_002251 potassium voltage-gated channel, delayed-rectifier, 20q12 4.1 subfamily S, member 1 parous promoter CXCR4 NM_003467 chemokine (C-X-C motif) receptor 4 2q21 46.9 parous promoter MSX1 NM_002448 msh homeobox 1 4p16.2 8.4 parous promoter KLF9 NM_001206 Kruppel-like factor 9 9q21.11 25 parous promoter HS3ST3B1 NM_006041 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 17p12 12.5 parous promoter CPT1A NM_001876 carnitine palmitoyltransferase 1A (liver) 11q13.2 2.7 parous promoter TFAP4 NM_003223 transcription factor AP-4 16p13 5.1 (activating enhancer binding protein 4) parous promoter SNTA1 NM_003098 syntrophin, alpha 1 (dystrophin-assodated 20q11.2 2.2 protein A1, 59 kDa, addic component) parous promoter CPT1B NM_152246 carnitine palmitoyltransferase 1B (muscle) 22q13.33 14.5 parous promoter LOC100144603 NR_021492 NA NA 14.5 parous promoter AP4M1 NM_004722 adaptor-related protein complex 4, mu 1 subunit 7q22.1 3.2 parous promoter RNF128 NM_194463 ring finger protein 128 Xq22.3 3 parous promoter MFSD5 NM_032889 major facilitator superfamily domain containing 5 12q13.13 8.7 parous promoter RTN2 NM_005619 reticulon 2 19q13.2-q13.3 4.7 parous promoter MCM7 NM_182776 minichromosome maintenance complex component 7 7q21.3-q22.1 3.2 parous promoter FAM19A5 NM_001082967 family with sequence similarity 19 22q13.32 2.4 (chemokine (C-C motif)-like), member A5 parous promoter HIST1H3D NM_003530 histone duster 1, H3d 6p22.1 3.2 parous promoter CASC4 NM_138423 cancer susceptibility candidate 4 15q15. 3.6 parous promoter VCX NM_013452 variable charge, X-linked Xp22.31 3.2 parous promoter ZNF860 NM_001137674 zinc finger protein 860 3p24.1 3.4 parous promoter VCX2 NM_016378 variable charge, X-linked 2 Xp22.32 3.2 parous promoter MEX3B NM_032246 mex-3 homolog B (C. elegans) 15q25.1 9.3 parous promoter SMOX NM_175842 spermine oxidase 20p13 4.9 parous promoter PTPRT NM_007050 protein tyrosine phosphatase, receptor type, T 20q12-q13 2.4 parous promoter VAMP5 NM_006634 vesicle-associated membrane protein 5 (myobrevin) 2p11.2 7.7 parous promoter SLC40A1 NM_014585 solute carrier family 40 2q32 77.9 (iron-regulated transporter), member 1 parous promoter SPAST NM_014946 spastin 2p24-p21 5.9 parous promoter DDX24 NM_020414 DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 14q32 4.2 parous promoter SRRM2 NM_016333 serine/arginine repetitive matrix 2 16p13.3 2.1 parous promoter NSUN7 NM_024677 NOL1/NOP2/Sun domain family, member 7 4p14 2.2 parous promoter PRCD NM_001077620 progressive rod-cone degeneration 17q25.1 10.4 parous promoter PSAT1 NM_058179 phosphoserine aminotransferase 1 9q21.2 21.5 parous promoter REC8 NM_005132 REC8 homolog (yeast) 14q11.2-qi2 165 parous promoter SCN1B NM_199037 sodium channel, voltage-gated, type I, beta 19 5.3 parous promoter UBE3C NM_014671 ubiquitin protein ligase E3C 7q36.3 7.5 parous promoter TCTEX1D2 NM_152773 Tctexl domain containing 2 3q29 2.1 parous promoter BCL6 NM_001130845 B-cell CLL/lymphoma 6 3q27 2.9 parous promoter TBC1D10B NM_015527 TBC1 domain family, member 10B 16p11.2 5 nulliparous promoter PGAP1 NM_024989 post-GPI attachment to proteins 1 2q33.1 −2.1 nulliparous promoter ZCCHC11 NM_001009881 zinc finger, CCHC domain containing 11 1p32.3 −3.6 nulliparous promoter AGL NM_000644 amylo-1,6-glucosidase, 4-alpha-glucanotransferase 1p21 −5.7 nulliparous promoter TMCO1 NM_019026 transmembrane and coiled-coil domains 1 1q22-q25 −5.7 nulliparous promoter LOC728024 NR_003671 NA NA −3.8 nulliparous promoter B2M NM_004048 beta-2-microglobulin 15q21- −3.8 nulliparous promoter RARS2 NM_020320 arginyl-tRNA synthetase 2, mitochondrial 6q16.1 −3.5 nulliparous promoter SEMA4C NM_017789 sema domain, immunoglobulin domain (Ig), 2q11.2 −2.4 transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C nulliparous promoter SEMA4F NM_004263 sema domain, immunoglobulin domain (Ig), 2p13.1 −2.4 transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F nulliparous promoter C1orf123 NM_017887 chromosome 1 open reading frame 123 1p32.3 −2.2 nulliparous promoter SMG7 NM_201569 Smg-7 homolog, nonsense mediated mRNA 1q25 −2.7 decay factor (C. elegans) nulliparous promoter SAMD12 NM_001101676 sterile alpha motif domain containing 12 8q24.12 −2.8 nulliparous promoter SAMD10 NM_080621 sterile alpha motif domain containing 10 20q13.33 −3.9 nulliparous promoter SQRDL NM_021199 sulfide quinone reductase-like (yeast) 15q15 −8.4 nulliparous promoter PTGER4 NM_000958 prostaglandin E receptor 4 (subtype EP4) 5p13.1 −9.5 nulliparous promoter NR0B1 NM_000475 nuclear receptor subfamily 0, group B, member 1 Xp21.3 −6.9 nulliparous promoter COMMD7 NM_001099339 COMM domain containing 7 20q11 −3 nulliparous promoter SLC6A17 NM_001010898 solute carrier family 6, member 17 1p13.2 −25.6 nulliparous promoter C3orf14 NM_020685 chromosome 3 open reading frame 3 −2.2 nulliparous promoter HEBP2 NM_014320 heme binding protein 2 6q24 −8.1 nulliparous promoter VAC14 NM_018052 Vac14 homolog (S. cerevisiae) 16q22.1 −2.6 nulliparous promoter VAC14 NM_018052 Vac14 homolog (S. cerevisiae) 16q22.1 −5.4 nulliparous promoter IL18 NM_001562 interleukin 18 (interferon-gamma-inducing factor) 11q22.2-q22.3 −3 nulliparous promoter JRKL NM_003772 jerky homolog-like (mouse) 11q21 −16.4 nulliparous promoter WIPI1 NM_017983 WD repeat domain, phosphoinositide interacting 1 17q24.2 −5.2 nulliparous promoter ZNF687 NM_020832 zinc finger protein 687 1q21.2 −32.1 nulliparous promoter STK3 NM_006281 serine/threonine kinase 3 (STE20 homolog, yeast) 8q22.2 −2.1 nulliparous promoter KHDC1 NM_030568 KH homology domain containing 1 6q13 −2.8 nulliparous promoter OCA2 NM_000275 oculocutaneous albinism II 15q11.2-qi2 −6 nulliparous promoter 38048 NM_178450 NA NA −2.1 nulliparous promoter GATA2 NM_032638 GATA binding protein 2 3q21 −3.6 nulliparous promoter CXCL14 NM_004887 chemokine (C-X-C motif) ligand 14 5q31 −2.2 nulliparous promoter AKAP5 NM_004857 A kinase (PRKA) anchor protein 5 14q21-q24 −3.3 nulliparous promoter UBE4A NM_004788 ubiquitination factor E4A (UFD2 homolog, yeast) 11q23.3 −2.5 nulliparous promoter TC2N NM_001128595 tandem C2 domains, nuclear 14q32.12 −23.5 nulliparous promoter LECT1 NM_001011705 leukocyte cell derived chemotaxin 1 13q14-q21 −2.3 nulliparous promoter HCN3 NM_020897 hyperpolarization activated cyclic 1q21.2 −3.6 nucleotide-gated potassium channel 3 nulliparous promoter C13orf27 NM_138779 chromosome 13 open reading frame 27 13q33.1 −2.5 nulliparous promoter TRAPPC5 NM_001042462 trafficking protein particle complex 5 19p13.3 −4.8 nulliparous promoter ARFRP1 NM_001134758 ADP-ribosylation factor related protein 1 20q13.3 −4 nulliparous promoter DDX47 NM_016355 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 12p13.2 −3.5 nulliparous promoter ZGPAT NM_001083113 zinc finger, CCCH-type with G patch domain 20q13.3 −4 nulliparous promoter RHBDD3 NM_012265 rhomboid domain containing 3 22q12.2 −6.3 nulliparous promoter C6orf159 NM_001009994 NA NA −2.6 nulliparous promoter EIF5A2 NM_020390 eukaryotic translation initiation 3q26.2 −15.4 nulliparous promoter YBX1 NM_004559 Y box binding protein 1 1p34 −2.7 nulliparous promoter YBX2 NM_015982 Y box binding protein 2 17p13. −3.2 nulliparous promoter YBX2 NM_015982 Y box binding protein 2 17p13. −3.3 nulliparous promoter DIRAS1 NM_145173 DIRAS family, GTP-binding RAS-like 1 19p13.3 −3.4 nulliparous promoter HMGN1 NM_004965 high-mobility group nucleosome binding domain 1 21q22.3 −2.9 nulliparous promoter DTL NM_016448 denticleless homolog (Drosophila) 1q32 −6 nulliparous promoter HACL1 NM_012260 2-hydroxyacyl-CoA lyase 1 3p24.3 −2.7 nulliparous promoter RARRES2 NM_002889 retinoic acid receptor responder (tazarotene induced) 2 7q36.1 −2.5 nulliparous promoter POLR3A NM_007055 polymerase (RNA) III (DNA directed) 10q22-q23 −3.8 polypeptide A, 155 kDa nulliparous promoter RAB6A NM_198896 RAB6A, member RAS oncogene family 11q13.3 −2.5 nulliparous promoter KIAA1279 NM_015634 KIAA1279 10q22.1 −2.5 nulliparous promoter GTF3C3 NM_012086 general transcription factor MIC, polypeptide 3, 102 kDa 2q33.1 −4.6 nulliparous promoter MGST3 NM_004528 microsomal glutathione S-transferase 3 1q23 −2.1 nulliparous promoter POLR1C NM_203290 polymerase (RNA) I polypeptide C, 30 kDa 6p21.1 −4.7 nulliparous promoter LOC100134229 NR_024451 NA NA −7.1 nulliparous promoter ISCA1 NM_030940 iron-sulfur cluster assembly 1 homolog (S. cerevisiae) 9q22.1 −4.4 nulliparous promoter SNORD68 NR_002450 small nucleolar RNA, C/D box 68 16q24.3 −3.1 nulliparous promoter PKHD1L1 NM_177531 polycystic kidney and hepatic 8q23 −2.9 disease 1 (autosomal recessive) like 1 nulliparous promoter PANK1 NM_148978 pantothenate kinase 1 10q23.31 −2.3 nulliparous promoter CYP11A1 NM_001099773 cytochrome P450, family 11, subfamily A, polypeptide 1 15q23-q24 −2.1 nulliparous promoter LOC541473 NR_003602 NA NA −2.2 nulliparous promoter SOX11 NM_003108 SRY (sex determining region Y)-box 11 2p25 −5.6 nulliparous promoter PCDHB11 NM_018931 protocadherin beta 11 5q31 −7.1 nulliparous promoter SOX17 NM_022454 SRY (sex determining region Y)-box 17 8q11.23 −2.2 nulliparous promoter BCDIN3D NM_181708 BCDIN3 domain containing 12q13.13 −3.9 nulliparous promoter PAICS NM_006452 phosphoribosylaminoimidazole carboxylase, 4pter-q21 −4.5 phosphoribosylaminoimidazole succinocarboxamide synthetase nulliparous promoter EFTUD1 NM_024580 elongation factor Tu GTP binding domain containing 1 15q25.2 −24.5 nulliparous promoter RSBN1L NM_198467 round spermatid basic protein 1-like 7q21.11 −4.7 nulliparous promoter DIO1 NM_001039715 deiodinase, iodothyronine, type I 1p33-p32 −2.1 nulliparous promoter ANKS6 NM_173551 ankyrin repeat and sterile alpha motif 9q31.1 −3.3 domain containing 6 nulliparous promoter DIO3 NM_001362 deiodinase, iodothyronine, type III 14q32 −7.7 nulliparous promoter OPCML NM_002545 opioid binding protein/cell adhesion molecule-like 11q25 −2.2 nulliparous promoter ZNF517 NM_213605 zinc finger protein 517 8q24.3 −11.2 nulliparous promoter PDLIM4 NM_001131027 PDZ and LIM domain 4 5q31.1 −2.7 nulliparous promoter CCDC53 NM_016053 coiled-coil domain containing 53 12q23.3 −2.2 nulliparous promoter UCK1 NM_001135954 uridine-cytidine kinase 1 9q34.1 −4 nulliparous promoter FIBCD1 NM_032843 fibrinogen C domain containing 1 9q34.2 −2.1 nulliparous promoter FIBCD1 NM_032843 fibrinogen C domain containing 1 9q34.2 19.8 nulliparous promoter C8orf45 NM_001136161 chromosome 8 open reading frame 45 8q13.1 −12.7 nulliparous promoter KCNQ5 NM_019842 potassium voltage-gated channel, 6q14 −10.6 KQT-like subfamily, member 5 nulliparous promoter KCNQ1 NM_000218 potassium voltage-gated channel, 11p15.5 −6 KQT-like subfamily, member 1 nulliparous promoter NFASC NM_015090 neurofascin homolog (chicken) 1q32.1 −3.3 nulliparous promoter HIST2H3C NM_021059 histone cluster 2, H3c 1q21.2 −5.3 nulliparous promoter HIST2H3A NM_001005464 histone cluster 2, H3a 1q21.2 −5.3 nulliparous promoter CNTFR NM_001842 ciliary neurotrophic factor receptor 9p13 −2.6 nulliparous promoter RTTN NM_173630 rotatin 18q22.1 −2.2 nulliparous promoter GARS NM_002047 glycyl-tRNA synthetase 7p15 −7.2 nulliparous promoter C5orf13 NM_004772 chromosome 5 open reading frame 13 5q22.1 −2.5 nulliparous promoter ZDHHC3 NM_001135179 zinc finger, DHHC-type containing 3 3p21.31 −7.1 nulliparous promoter SAMD11 NM_152486 sterile alpha motif domain 1p36.33 −6 nulliparous promoter ERMP1 NM_024896 endoplasmic reticulum metallopeptidase 1 9p24 −2.6 nulliparous promoter FBXO34 NM_152231 F-box protein 34 14q22.1 −25.5 nulliparous promoter ZNF703 NM_025069 zinc finger protein 703 8p12 −2.4 nulliparous promoter WDR37 NM_014023 WD repeat domain 37 10p15.3 −2.3 nulliparous promoter ZNF26 NM_019591 zinc finger protein 26 12q24.33 −2.4 nulliparous promoter FLNB NM_001457 filamin B, beta 3p14.3 −4.3 nulliparous promoter MINPP1 NM_004897 multiple inositol polyphosphate 10q23 −2.1 histidine phosphatase, 1 nulliparous promoter NAB2 NM_005967 NGFI-A binding protein 2 12q13.3 −4.3 (EGR1 binding protein 2) nulliparous promoter FLJ45244 NR_015415 NA NA −8.5 nulliparous promoter SOAT1 NM_003101 sterol O acyltransferase 1 1q25 4 nulliparous promoter FLJ45537 NM_001001709 NA NA −2.9 nulliparous promoter SNORD74 NR_002579 small nucleolar RNA, C/D box 74 1q25.1 −9.1 nulliparous promoter SESN3 NM_144665 sestrin 3 11q21 −2.7 nulliparous promoter SNORD47 NR_002746 small nucleolar RNA, C/D box 47 1q25.1 −9.1 nulliparous promoter RCAN3 NM_013441 RCAN family member 3 1p35.3-p33 −5.1 nulliparous promoter VAPB NM_004738 VAMP (vesicle-associated membrane protein)- 20q13 −2.6 associated protein B and C nulliparous promoter SMAD2 NM_001003652 SMAD family member 2 18q21 −2.6 nulliparous promoter SLC4A4 NM_001098484 solute carrier family 4, sodium bicarbonate 4q21 −3.3 cotransporter, member 4 nulliparous promoter ZNF839 NM_018335 zinc finger protein 839 14q32.32 −3.5 nulliparous promoter NELL2 NM_006159 NEL-like 2 (chicken) 12q12 −6.9 nulliparous promoter SNORA62 NR_002324 small nucleolar RNA, H/ACA box 62 3p22 −5.9 nulliparous promoter HTRA3 NM_053044 HtrA serine peptidase 3 4p16.1 −2.5 nulliparous promoter GDAP1 NM_018972 ganglioside-induced differentiation-associated protein 1 8q13.3 −13.8 nulliparous promoter PLRG1 NM_002669 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis) 4q31.2-q32.1 −4.8 nulliparous promoter ASPH NM_004318 aspartate beta-hydroxylase 8q12.1 −4.9 nulliparous promoter ARF5 NM_001662 ADP-ribosylation factor 5 7q31.3 −4.8 nulliparous promoter ACAT2 NM_005891 acetyl-Coenzyme A acetyltransferase 2 6q25.3-q26 −2.4 nulliparous promoter PCDHB10 NM_018930 protocadherin beta 10 5q31 −7.1 nulliparous promoter PBK NM_018492 PDZ binding kinase 8p21.2 −5.2 nulliparous promoter TM9SF3 NM_020123 transmembrane 9 superfamily member 3 10q24.2 −5.2 nulliparous promoter PTTG1 NM_004219 pituitary tumor-transforming 1 5q35.1 −6.8 nulliparous promoter WBSCR17 NM_022479 Williams-Beuren syndrome chromosome region 17 7q11.23 −2.4 nulliparous promoter WBSCR16 NM_030798 Williams-Beuren syndrome chromosome region 16 7q11.23 −2.9 nulliparous promoter CLINT1 NM_014666 clathrin interactor 1 5q33.3 −4 nulliparous promoter CYP20A1 NM_177538 cytochrome P450, family 20, subfamily A, polypeptide 1 2q33 −2.4 nulliparous promoter TMEM26 NM_178505 transmembrane protein 26 10q21.3 −2.2 nulliparous promoter LTK NM_002344 leukocyte receptor tyrosine kinase 15q15.1-q21.1 −6.7 nulliparous promoter DHFRL1 NM_176815 dihydrofolate reductase-like 1 3q11.2 −3.1 nulliparous promoter ANKRD20B NR_003366 ankyrin repeat domain 20B 2q11.1 −6 nulliparous promoter TNFAIP8 NM_001077654 tumor necrosis factor, alpha-induced protein 8 5q23.1 −7.7 nulliparous promoter CAPZA2 NM_006136 capping protein (actin filament) muscle Z-line, alpha 2 7q31.2-q31.3 −2.7 nulliparous promoter TAF1A NM_139352 TATA box binding protein (TBP)-associated factor, 1q42 −20.6 RNA polymerase I, A, 48 kDa nulliparous promoter GPR150 NM_199243 G protein-coupled receptor 150 5q15 −11.5 nulliparous promoter RAB33B NM_031296 RAB33B, member RAS oncogene family 4q28 −11.6 nulliparous promoter MED30 NM_080651 mediator complex subunit 30 8q24.11 −2.7 nulliparous promoter LMO3 NM_001001395 LIM domain only 3 (rhombotin-like 12p13 −3.7 nulliparous promoter ABCA5 NM_172232 ATP-binding cassette, sub-family A (ABC1), member 5 17q21-q25 −2.7 nulliparous promoter CXXC4 NM_025212 CXXC finger 4 4q22-q24 −2.9 nulliparous promoter MYL6B NM_002475 myosin, light chain 6B, alkali, smooth muscle 12q13.2 -2.3 and non-muscle nulliparous promoter TUBGCP5 NM_001102610 tubulin, gamma complex associated protein 5 15q11.1 −6.3 nulliparous promoter TUBGCP5 NM_001102610 tubulin, gamma complex associated protein 5 15q11.1 −3.9 nulliparous promoter CCBL2 NM_019610 cysteine conjugate-beta lyase 2 1p22.2 −3.1 nulliparous promoter RBM6 NM_005777 RNA binding motif protein 6 3p21.3 −6.4 nulliparous promoter CUEDC1 NM_017949 CUE domain containing 1 17q23.2 −4 nulliparous promoter ACTR10 NM_018477 actin-related protein 10 homolog (S. cerevisiae) 14q22.3 −3.3 nulliparous promoter STT3A NM_152713 STT3, subunit of the oligosaccharyltransferase 11q23.3 −5.1 complex, homolog A (S. cerevisiae) nulliparous promoter PIGY NM_001042616 phosphatidylinositol glycan anchor biosynthesis, 4q22.1 −5.1 class Y nulliparous promoter TH1L NM_198976 TH1-like (Drosophila) 20q13 −2.2 nulliparous promoter RBMXL2 NM_014469 RNA binding motif protein, X-linked-like 2 11p15 −8.9 nulliparous promoter EPS8 NM_004447 epidermal growth factor receptor pathway substrate 8 12p12.3 −5.4 nulliparous promoter TXNL4A NM_006701 thioredoxin-like 4A 18q23 −5 nulliparous promoter RB1CC1 NM_001083617 RB1-inducible coiled-coil 1 8q11 −7 nulliparous promoter CPSF1 NM_013291 cleavage and polyadenylation specific factor 1,160 kDa 8q24 −7.8 nulliparous promoter CPSF1 NM_013291 cleavage and polyadenylation specific factor 1,160 kDa 8q24 2.6 nulliparous promoter SIM1 NM_005068 single-minded homolog 1 (Drosophila) 6q16.3-q21 −3 nulliparous promoter TOB1 NM_005749 transducer of ERBB2, 1 17q21 −5.3 nulliparous promoter TP53TG3 NM_016212 TP53 target 3 16p13 −3.8 nulliparous promoter PPFIA1 NM_177423 protein tyrosine phosphatase, receptor type, 11q13.3 −2.6 f polypeptide (PTPRF), interacting protein (liprin), alpha 1 nulliparous promoter TMEM41A NM_080652 transmembrane protein 41A 3q27.2 −4.1 nulliparous promoter DPYS NM_001385 dihydropyrimidinase 8q22 −2.9 nulliparous promoter NEO1 NM_002499 neogenin homolog 1 (chicken) 15q22.3-q23 −2.5 nulliparous promoter CDCA7 NM_031942 cell division cycle associated 7 2q31.1 −7.4 nulliparous promoter GPR120 NM_181745 G protein-coupled receptor 120 10q23.33 −4.4 nulliparous promoter CLIP4 NM_024692 CAP-GLY domain containing linker protein 2p23 −2.6 family, member 4 nulliparous promoter DYNLRB2 NM_130897 dynein, light chain, roadblock-type 2 16q23.3 −3.2 nulliparous promoter HSD17B4 NM_000414 hydroxysteroid (17-beta) dehydrogenase 4 5q2 -G nulliparous promoter CNOT6 NM_015455 CCR4-NOT transcription complex, subunit 6 5q35.3 -7.5 nulliparous promoter PCDH17 NM_001040429 protocadherin 17 13q21.1 −5.4 nulliparous promoter TTLL1 NM_001008572 tubulin tyrosine ligase-like family, member 1 22q13.1 −6.1 nulliparous promoter HEATR3 NM_182922 HEAT repeat containing 3 16q12.1 −3.9 nulliparous promoter NLGN4X NM_020742 neuroligin 4, X-linked Xp22.33 −7.6 nulliparous promoter KIF18A NM_031217 kinesin family member 18A 11p14.1 −9.8 nulliparous promoter PTGR1 NM_012212 prostaglandin reductase 1 9q32 −2.7 nulliparous promoter GAS1 NM_002048 growth arrest-specific 1 9q21.3-q22 −5.2 nulliparous promoter ATG4D NM_032885 ATG4 autophagy related 4 homolog D (S. cerevisiae) 19p13.2 −2.4 nulliparous promoter MMP25 NM_022468 matrix metallopeptidase 25 16p13.3 −2.7 nulliparous promoter MEX3D NM_203304 mex-3 homolog D (C. elegans) 19p13.3 −4.9 nulliparous promoter TRIP13 NM_004237 thyroid hormone receptor interactor 13 5p15 −6.1 nulliparous promoter HOXB13 NM_006361 homeobox B13 17q21.32 −2.3 nulliparous promoter SLC35F5 NM_025181 solute carrier family 35, member F5 2q14.1 −4.3 nulliparous promoter SNW1 NM_012245 SNW domain containing 1 14q22.1-q22.3 −2.8 nulliparous promoter WASF2 NM_006990 WAS protein family, member 2 1p36.11 −3.5 nulliparous promoter SLC35F2 NM_017515 solute carrier family 35, member F2 11q23.1 −2.8 nulliparous promoter YRDC NM_024640 yrdC domain containing (E. coli) 1p34.3 −3.3 nulliparous promoter SLU7 NM_006425 SLU7 splicing factor homolog (S. cerevisiae) 5q33.3 −6.8 nulliparous promoter COX15 NM_004376 COX15 homolog, cytochrome c oxidase 10q24 −4 assembly protein (yeast) nulliparous promoter ZNF468 NM_001008801 zinc finger protein 468 19q13.41 −10.5 nulliparous promoter FUT4 NM_002033 fucosyltransferase 4 (alpha (1,3) 11q12-qter −4.1 fucosyltransferase, myeloid-specific) nulliparous promoter FUT1 NM_000148 fucosyltransferase 1 (galactoside 19q13.1-qter −5.5 2-alpha-L-fucosyltransferase, H blood group) nulliparous promoter CMTM3 NM_001048251 CKLF-like MARVEL transmembrane 16q22.1-q22.3 −2.3 domain containing 3 nulliparous promoter EWSR1 NM_005243 Ewing sarcoma breakpoint region 1 22q12.2 −6.3 nulliparous promoter IL1RL2 NM_003854 interleukin 1 receptor-like 2 2q12 -2.1 nulliparous promoter ATP5J2 NM_004889 ATP synthase, H+ transporting, mitochondrial 7q22.1 -6.3 F0 complex, subunit F2 nulliparous promoter UFC1 NM_016406 ubiquitin-fold modifier conjugating enzyme 1 1q23.3 −6.7 nulliparous promoter HNRPLL NM_138394 heterogeneous nuclear ribonucleoprotein L-like 2p22 −5.3 nulliparous promoter SFMBT1 NM_001005159 Scm-like with four mbt domains 1 3p21.31 −2.7 nulliparous promoter SFMBT2 NM_001029880 Scm-like with four mbt domains 2 10p15. −3.3 nulliparous promoter EHD4 NM_139265 EH-domain containing 4 15q11.1 −11.2 nulliparous promoter REXO4 NM_020385 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 9q34 −3.6 nulliparous promoter USP29 NM_020903 ubiquitin specific peptidase 29 19q13.4 −6.4 nulliparous promoter RASAL1 NM_004658 RAS protein activator like 1 (GAP1 like) 12q23-q24 −3.4 nulliparous promoter DEPDC1B NM_018369 DEP domain containing 1B 5q12 −2.1 nulliparous promoter USP21 NM_001014443 ubiquitin specific peptidase 21 1q22 −6.7 nulliparous promoter PRPF6 NM_012469 PRP6 pre-mRNA processing factor 20q13.33 −3.9 6 homolog (S. cerevisiae) nulliparous promoter C20orf94 NM_001009608 chromosome 20 open reading frame 94 20p12 −10.4 nulliparous promoter NFE2L2 NM_006164 nuclear factor (erythroid-derived 2)-like 2 2q31 −11.6 nulliparous promoter ARHGEF5 NM_005435 Rho guanine nucleotide exchange factor (GEF) 5 7q33-q35 −3.8 nulliparous promoter EIF3E NM_001568 eukaryotic translation initiation factor 3, subunit E 8q22-q23 −4.1 nulliparous promoter NDUFA11 NM_175614 NADH dehydrogenase (ubiquinone) 19p13.3 −5.4 1 alpha subcomplex, 11, 14.7 kDa nulliparous promoter WNK3 NM_001002838 WNK lysine deficient protein kinase 3 Xp11.22 −11.6 nulliparous promoter MTMR7 NM_004686 myotubularin related protein 7 8p22 −3.7 nulliparous promoter MKKS NM_170784 McKusick-Kaufman syndrome 20p12 −10.4 nulliparous promoter SPIN1 NM_006717 spindlin 1 9q22.1 −4.4 nulliparous promoter C2orf55 NM_207362 chromosome 2 open reading frame 55 2q11.2 −3.9 nulliparous promoter RSPO3 NM_032784 R-spondin 3 homolog (Xenopus laevis) 6q22.33 −2.4 nulliparous promoter TBCCD1 NM_018138 TBCC domain containing 1 3q27.3 −2.7 nulliparous promoter LIPJ NM_001010939 lipase, family member J 10q23.31 −2.2 nulliparous promoter RAMP3 NM_005856 receptor (G protein-coupled) activity 7p13-p12 −5.5 modifying protein 3 nulliparous promoter WDR21A NM_015604 NA NA −2.8 nulliparous promoter TNFRSF21 NM_014452 tumor necrosis factor receptor superfamily, member 21 6p21.1 −6.6 nulliparous promoter SSH2 NM_033389 slingshot homolog 2 (Drosophila) 17q11.2 −4.5 nulliparous promoter HRK NM_003806 harakiri, BCL2 interacting protein 12q24.2 −2.6 (contains only BH3 domain) nulliparous promoter SNAI2 NM_003068 snail homolog 2 (Drosophila) 8q11.21 −7.9 nulliparous promoter SYT8 NM_138567 synaptotagmin VIII 11p15.5 −2.1 nulliparous promoter SLC2A9 NM_020041 solute carrier family 2 (facilitated glucose transporter), 4p16.1 −9.5 member 9 nulliparous promoter SLC2A8 NM_014580 solute carrier family 2 (facilitated glucose transporter), 9q33.3 −2.1 member 8 nulliparous promoter SLC2A4 NM_001042 solute carrier family 2 (facilitated glucose transporter), 17p13 −7.5 member 4 nulliparous promoter RCOR1 NM_015156 REST corepressor 1 14q32.33 −2.8 nulliparous promoter PLEKHA5 NM_019012 pleckstrin homology domain containing, 12p12 −5.8 family A member 5 nulliparous promoter TIGD2 NM_145715 tigger transposable element derived 2 4q21.3 −4.9 nulliparous promoter FAM36A NM_198076 family with sequence similarity 36, member A 1q44 −3.4 nulliparous promoter FAM36A NM_198076 family with sequence similarity 36, member A 1q44 −8.1 nulliparous promoter HCRTR1 NM_001525 hypocretin (orexin) receptor 1 1p33 −2.2 nulliparous promoter YIPF3 NM_015388 Yip1 domain family, member 3 6p21.1 −4.7 nulliparous promoter TMEM42 NM_144638 transmembrane protein 42 3p21.31 −4.9 nulliparous promoter SNX3 NM_003795 sorting nexin 3 6q21 −2.9 nulliparous promoter SNX3 NM_003795 sorting nexin 3 6q21 5.9 nulliparous promoter DMRT2 NM_001130865 doublesex and mab-3 related transcription factor 2 9p24.3 −3.1 nulliparous promoter ALG5 NM_013338 asparagine-linked glycosylation 5, 13q13.1 −2.7 dolichyl-phosphate beta- glucosyltransferase homolog (S. cerevisiae) nulliparous promoter DHX38 NM_014003 DEAH (Asp-Glu-Ala-His) box polypeptide 38 16q22 −2.9 nulliparous promoter FAM73A NM_198549 family with sequence similarity 73, member A 1p31.1 −7.5 nulliparous promoter EXOSC8 NM_181503 exosome component 8 13q13. −2.7 nulliparous promoter SLC29A3 NM_018344 solute carrier family 29 (nucleoside 10q22.2 −3.8 transporters), member 3 nulliparous promoter STAM NM_003473 signal transducing adaptor molecule 10p14-p13 −2.8 (SH3 domain and ITAM motif) 1 nulliparous promoter EXOSC7 NM_015004 exosome component 7 3p21.32 −7.1 nulliparous promoter METT5D1 NM_152636 methyltransferase 5 domain containing 1 11p14.1 −9.8 nulliparous promoter YPEL1 NM_013313 yippee-like 1 (Drosophila) 22q11.2 −4.2 nulliparous promoter NEK3 NM_002498 NIMA (never in mitosis gene a)-related kinase 3 13q14.2-q21.1 −9.2 nulliparous promoter ADAMTSL5 NM_213604 ADAMTS-like 5 19p13.3 −6.7 nulliparous promoter FLJ22167 NM_001077416 NA NA −7.2 nulliparous promoter TPTE NM_199261 transmembrane phosphatase with tensin homology 21p11 −2.1 nulliparous promoter NID1 NM_002508 nidogen 1 1q43 −2.7 nulliparous promoter C10orf59 NM_001031709 NA NA −2.2 nulliparous promoter GCC1 NM_024523 GRIP and coiled-coil domain containing 1 7q22.3 −4.8 nulliparous promoter LCN12 NM_178536 lipocalin 12 9q34 −2.7 nulliparous promoter TACSTD2 NM_002353 tumor-associated calcium signal transducer 2 1p32 −4.2 nulliparous promoter GPR160 NM_014373 G protein-coupled receptor 160 3q26.2-q27 −3.6 nulliparous promoter GPR161 NM_153832 G protein-coupled receptor 161 1q23.3 −2.1 nulliparous promoter PLXDC2 NM_032812 plexin domain containing 2 10p12.33 −5 nulliparous promoter TCF4 NM_001083962 transcription factor 4 18q21.1 −3 nulliparous promoter FABP5L3 NR_002935 fatty acid binding protein 5-like 3 (pseudogene) 7q36.1 −4.6 nulliparous promoter ZNF746 NM_152557 zinc finger protein 746 7q36.1 −3.2 nulliparous promoter NUDT3 NM_006703 nudix (nucleoside diphosphate linked 6p21.2 −2.6 moiety X)-type motif 3 nulliparous promoter MLLT10 NM_004641 myeloid/lymphoid or mixed-lineage leukemia 10p12 −2.5 (trithorax homolog, Drosophila); translocated to, 10 nulliparous promoter UBE2E2 NM_152653 ubiquitin-conjugating enzyme E2E 2 3p24.2 −8.4 (UBC4/5 homolog, yeast) nulliparous promoter CNGA3 NM_001298 cyclic nucleotide gated channel alpha 3 2q11.2 −3.1 nulliparous promoter SNORD76 NR_003942 small nucleolar RNA, C/D box 76 1q25.1 −9.1 nulliparous promoter MANSC1 NM_018050 MANSC domain containing 1 12p13.2 −4.1 nulliparous promoter LOC256880 NR_002799 NA NA −2.1 nulliparous promoter SNORD75 NR_003941 small nucleolar RNA, C/D box 75 1q25.1 −9.1 nulliparous promoter BLVRA NM_000712 biliverdin reductase A 7p14-cen −19 nulliparous promoter SNORD79 NR_003939 small nucleolar RNA, C/D box 79 1q25.1 −9.1 nulliparous promoter C15orf24 NM_020154 chromosome 15 open reading frame 24 15q14 −3.8 nulliparous promoter PRRX2 NM_016307 paired related homeobox 2 9q34.11 −3.1 nulliparous promoter IRF7 NM_004031 interferon regulatory factor 7 11p15.5 −2.5 nulliparous promoter PAIP2B NM_020459 poly(A) binding protein interacting protein 2B 2p13.3 −6.4 nulliparous promoter MPZL1 NM_003953 myelin protein zero-like 1 1q24.2 −5 nulliparous promoter COX18 NM_173827 COX18 cytochrome c oxidase assembly 4q13.3 −4.7 homolog (S. cerevisiae) nulliparous promoter BTD NM_000060 biotinidase 3p25 −2.7 nulliparous promoter PFN2 NM_002628 profilin 2 3q25.1 −3.8 nulliparous promoter HS6ST1 NM_004807 heparan sulfate 6-0-sulfotransferase 1 2q21 −3.9 nulliparous promoter DEPDC4 NM_152317 DEP domain containing 4 12q23 −2.1 nulliparous promoter SHISA3 NM_001080505 shisa homolog 3 (Xenopus laevis) 4p13 −3.8 nulliparous promoter COX10 NM_001303 COX10 homolog, cytochrome c oxidase 17p12 −2.6 assembly protein, heme A:farnesyltransferase (yeast) nulliparous promoter CLK2 NM_003993 CDC-like kinase 2 1q21 −3.6 nulliparous promoter SCN5A NM_198056 sodium channel, voltage-gated, type V, alpha subunit 3p21 −5.2 nulliparous promoter GAS5 NR_002578 growth arrest-specific 5 (non-protein coding) 1q25.1 −9.1 nulliparous promoter ISLR2 NM_001130136 immunoglobulin superfamily containing 15q24.1 3.9 leucine-rich repeat 2 nulliparous promoter ISLR2 NM_001130136 immunoglobulin superfamily containing 15q24.1 −2.4 leucine-rich repeat 2 nulliparous promoter SNORA6 NR_002325 small nucleolar RNA, H/ACA box 6 3p22.2 −5.9 nulliparous promoter ZNF334 NM_018102 2inc finger protein 334 20 −6.2 nulliparous promoter APIP NM_015957 APAF1 interacting protein 11p13 −13.1 nulliparous promoter CUGBP2 NM_006561 CUG triplet repeat, RNA binding protein 2 10p13 −3 nulliparous promoter SCYL2 NM_017900 SCYHike 2 (S. cerevisiae) 12q23.1 −2.1 nulliparous promoter AHI1 NM_001134830 Abelson helper integration site 1 6q23.2 −2.2 nulliparous promoter TEX12 NM_031275 testis expressed 12 11 −3 nulliparous promoter TTBK2 NM_173500 tau tubulin kinase 2 15q15.2 −6 nulliparous promoter C21orf45 NM_018944 chromosome 21 open reading frame 45 21q22.11 −2.1 nulliparous promoter TMSB10 NM_021103 thymosin beta 10 2p11.2 −14.2 nulliparous promoter STXBP5 NM_001127715 syntaxin binding protein 5 (tomosyn) 6q24.3 −4.3 nulliparous promoter PPA2 NM_006903 pyrophosphatase (inorganic) 2 4q25 −3.8 nulliparous promoter PPA2 NM_006903 pyrophosphatase (inorganic) 2 4q25 −2.6 nulliparous promoter OXSR1 NM_005109 oxidative-stress responsive 1 3p22.2 −6.8 nulliparous promoter CBX8 NM_020649 chromobox homolog 8 (Pc class homolog, Drosophila) 17q25.3 −8 nulliparous promoter GPR78 NM_080819 G protein-coupled receptor 78 4p16.1 −3.4 nulliparous promoter ARHGAP29 NM_004815 Rho GTPase activating protein 29 1p22.1 −6.6 nulliparous promoter PION NM_017439 pigeon homolog (Drosophila) 7q11.23 −2.5 nulliparous promoter PION NM_017439 pigeon homolog (Drosophila) 7q11.23 15.4 nulliparous promoter ALCAM NM_001627 activated leukocyte cell adhesion molecule 3q13.1 −2.9 nulliparous promoter ALCAM NM_001627 activated leukocyte cell adhesion molecule 3q13.1 −4.7 nulliparous promoter KIAA1958 NM_133465 KIAA1958 9q33.1 −2.3 nulliparous promoter CST3 NM_000099 cystatin C 20p11.2 −6.4 nulliparous promoter E2F7 NM_203394 E2F transcription factor 7 12q21.1 −3.4 nulliparous promoter NTF3 NM_001102654 neurotrophin 3 12p13 −2.2 nulliparous promoter MTMR12 NM_001040446 myotubularin related protein 12 5p15.33 −3.4 nulliparous promoter SNORD77 NR_003943 small nucleolar RNA, C/D box 77 1q25.1 −9.1 nulliparous promoter DUSP5 NM_004419 dual specificity phosphatase 5 10q25 −18.6 nulliparous promoter ELMOD2 NM_153702 ELMO/CED-12 domain containing 2 4q31.1 −9.5 nulliparous promoter SND1 NM_014390 staphylococcal nuclease and tudor domain containing 1 7q31.3 −3.2 nulliparous promoter JOSD1 NM_014876 Josephin domain containing 1 22q13.1 −3.3 nulliparous promoter ALDH18A1 NM_001017423 aldehyde dehydrogenase 18 family, member A1 10q24.3-q24.6 −4.6 nulliparous promoter NAT11 NM_024771 N-acetyltransferase 11 (GCN5-related, putative) 11q13.1 −3.4 nulliparous promoter SLMO1 NM_006553 slowmo homolog 1 (Drosophila) 18p11.21 −2.8 nulliparous promoter PIP5K3 NM_152671 NA NA −2.4 nulliparous promoter MLL3 NM_170606 myeloid/lymphoid or mixed-lineage leukemia 3 7q36 −4.6 nulliparous promoter KIF1B NM_183416 kinesin family member 1B 1p36.22 −3.8 nulliparous promoter PIP5K1C NM_012398 phosphatidylinositol-4-phosphate 19p13.3 −3.4 5-kinase, type I, gamma nulliparous promoter GRIK1 NM_175611 glutamate receptor, ionotropic, kainate 1 21q22 −2.2 nulliparous promoter LRRC34 NM_153353 leucine rich repeat containing 34 3q26.2 −4.4 nulliparous promoter TFIP11 NM_012143 tuftelin interacting protein 11 22q12.1 −5.4 nulliparous promoter RNF149 NM_173647 ring finger protein 149 2q12.1 −2.8 nulliparous promoter HOXA5 NM_019102 homeobox A5 7p15.2 −9.9 nulliparous promoter PPAT NM_002703 phosphoribosyl pyrophosphate amidotransferase 4q21 −4.5 nulliparous promoter CKAP2L NM_152515 cytoskeleton associated protein 2-like 2q13 −4.9 nulliparous promoter DKFZP434B0335 NM_015395 NA NA −3.1 nulliparous promoter USP8 NM_005154 ubiquitin specific peptidase 8 15q21.1 −4.3 nulliparous promoter TGFB2 NM_003238 transforming growth factor, beta 2 1q41 −4.3 nulliparous promoter MGLL NM_007283 monoglyceride lipase 3p13-q13.33 −4.3 nulliparous promoter LIMS3 NM_033514 LIM and senescent cell antigen-like domains 3 2q14-q21 −3 nulliparous promoter PRSS3 NM_007343 protease, serine, 3 9p13 −4.2 nulliparous promoter RNF38 NM_022781 ring finger protein 38 9p −23.9 nulliparous promoter LOC201229 NM_001076680 NA NA −2.1 nulliparous promoter SMARCA5 NM_003601 SWI/SNF related, matrix associated, actin dependent 4q31.1-q31.2 −6.6 regulator of chromatin, subfamily a, member 5 nulliparous promoter SIAH1 NM_001006610 seven in absentia homolog 1 (Drosophila) 16q12 −8.4 nulliparous promoter CNIH3 NM_152495 cornichon homolog 3 (Drosophila) 1q42.12 −3.2 nulliparous promoter UNC119 NM_005148 unc-119 homolog (C. elegans) 17q11.2 −10.7 nulliparous promoter ICA1 NM_022307 islet cell autoantigen 1, 69 kDa 7p22 −3 nulliparous promoter RND3 NM_005168 Rho family GTPase 3 2q23.3 −4.9 nulliparous promoter DNAJC10 NM_018981 DnaJ (Hsp40) homolog, subfamily C, member 10 2q32.1 −4 nulliparous promoter CEBPZ NM_005760 CCAAT/enhancer binding protein (C/EBP), zeta 2p22.3 −6.4 nulliparous promoter NANS NM_018946 N-acetylneuraminic acid synthase 9p24.1-p23 −3.9 nulliparous promoter C3orf38 NM_173824 chromosome 3 open reading frame 38 3p11.1 −6.4 nulliparous promoter CCT6A NM_001009186 chaperonin containing TCP1, subunit 6A (zeta 1) 7p11.2 −4.1 nulliparous promoter GALNT11 NM_022087 UDP-N-acetyl-alpha-D-galactosamine:polypeptide 7q36.1 −3.7 N-acetylgalactosaminyltransferase 11 (GalNAc-T 11) nulliparous promoter ST3GAL1 NM_003033 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 8q24.22 −9.4 nulliparous promoter INTS7 NM_015434 integrator complex subunit 7 1q32.3 −6 nulliparous promoter ATAD3A NM_018188 ATPase family, AAA domain containing 3A 1p36.33 −3.2 nulliparous promoter CDC42EP1 NM_152243 CDC42 effector protein (Rho GTPase binding) 1 22q13.1 −11.1 nulliparous promoter ZBTB8 NM_001040441 NA NA −2.4 nulliparous promoter VCL NM_014000 vinculin 10q22.1-q23 −3.7 nulliparous promoter CHRM2 NM_000739 cholinergic receptor, muscarinic 2 7q35-q36 −6 nulliparous promoter HIST1H3B NM_003537 histone cluster 1, H3b 6p22.1 −3.7 nulliparous promoter MGAT1 NM_002406 mannosyl (alpha-1,3-)-glycoprotein 5 −2.7 beta-1,2-N-acetylglucosaminyltransferase nulliparous promoter ORC3L NM_012381 origin recognition complex, subunit 3-like (yeast) 6q −3.5 nulliparous promoter MTSS1 NM_014751 metastasis suppressor 1 8p22 −2.5 nulliparous promoter MTSS1 NM_014751 metastasis suppressor 1 8p22 −3.5 nulliparous promoter MGC16385 NM_145039 NA NA −2.2 nulliparous promoter LOC389332 NR_024418 NA NA −2.1 nulliparous promoter CADPS NM_183393 Ca++-dependent secretion activator 3p21.1 −2.9 nulliparous promoter SLC16A9 NM_194298 solute carrier family 16, member 9 10q21.3 −2.8 (monocarboxylic acid transporter 9) nulliparous promoter BAI1 NM_001702 brain-specific angiogenesis inhibitor 1 8q24 −2.3 nulliparous promoter DDX21 NM_004728 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 10q21 −2.5 nulliparous promoter NSUN3 NM_022072 NOL1/NOP2/Sun domain family, member 3 3q11.2 −3.1 nulliparous promoter NRIP1 NM_003489 nuclear receptor interacting protein 1 21q11.2 −8.4 nulliparous promoter C20orf103 NM_012261 chromosome 20 open reading frame 103 20p12 −7.8 nulliparous promoter BTC NM_001729 betacellulin 4q13-q21 −4.4 nulliparous promoter TWISTNB NM_001002926 TWIST neighbor 7p15.3 −2.4 nulliparous promoter psiTPTE22 NR_001591 NA NA −6.8 nulliparous promoter FLVCR2 NM_017791 feline leukemia virus subgroup C cellular 14q24.2 3 receptor family, member 2 nulliparous promoter C1orf122 NM_198446 chromosome 1 open reading frame 122 1p34.3 −3.3 nulliparous promoter SLC6A6 NM_001134368 solute carrier family 6 (neurotransmitter 3p26-p24 −5.6 transporter, taurine), member 6 nulliparous promoter SLC6A4 NM_001045 solute carrier family 6 (neurotransmitter 17q11.2 −6.8 transporter, serotonin), member 4 nulliparous promoter RRP7B NR_002184 ribosomal RNA processing 7 homolog B 22q13.2 −2.3 (S. cerevisiae) nulliparous promoter MCC26718 NM_001029999 NA NA −3.3 nulliparous promoter C1orf74 NM_152485 chromosome 1 open reading frame 74 1q32.2 −3.4 nulliparous promoter CCNT1 NM_001240 cyclin T1 12q13.11 −2.1 nulliparous promoter SLC30A7 NM_133496 solute carrier family 30 (zinc transporter), member 7 1p21.1 −5.1 nulliparous promoter C7orf58 NM_001105533 chromosome 7 open reading frame 58 7q31.31 −2.5 nulliparous promoter TOMM5 NM_001001790 translocase of outer mitochondrial membrane 9p13.2 −4 5 homolog (yeast) nulliparous promoter SNORD78 NR_003944 small nucleolar RNA, C/D box 78 1q25.1 −9.1 nulliparous promoter THRB NM_001128176 thyroid hormone receptor, beta (erythroblastic 3p24.1-p22 −13.5 leukemia viral (v-erb-a) oncogene homolog 2, avian) nulliparous promoter DCC NM_005215 deleted in colorectal carcinoma 18q21.1 −7.4 nulliparous promoter PARD6A NM_001037281 par-6 partitioning defective 6 homolog 16q22.1-q22.3 −5.8 alpha (C. elegans) nulliparous promoter SNORD44 NR_002750 small nucleolar RNA, C/D box 44 1q25.1 −9.1 nulliparous promoter KIAA1012 NM_014939 KIAA1012 18q12.1 −2.1 nulliparous promoter FAM110B NM_147189 family with sequence similarity 110, member B 8q12.1 −2.4 nulliparous promoter NPAL2 NM_024759 NA NA −3.4 nulliparous promoter ZNF577 NR_024181 zinc finger protein 577 19 −4.1 nulliparous promoter NUP214 NM_005085 nucleoporin 214 kDa 9q34 −17.6 nulliparous promoter VSX1 NM_014588 visual system homeobox 1 20p11.21 −4.8 nulliparous promoter VSX1 NM_014588 visual system homeobox 1 20p11.21 3.2 nulliparous promoter A1BG NM_130786 alpha-1-B glycoprotein 19q −2.3 nulliparous promoter PNKP NM_007254 polynucleotide kinase 3′-phosphatase 19q13.3-q13.4 −4.8 nulliparous promoter LRRC4 NM_022143 leucine rich repeat containing 4 7q31 −4.5 nulliparous promoter GUSB NM_000181 glucuronidase, beta 7q11.21 −5.8 nulliparous promoter EXTL2 NM_001439 exostoses (multiple)-like 2 1p21 −5.1 nulliparous promoter DNAJB14 NM_001031723 DnaJ (Hsp40) homolog, subfamily B, member 14 4q23 −2.1 nulliparous promoter CDH24 NM_022478 cadherin-like 24 14q11.2 −7.7 nulliparous promoter LRRC1 NM_018214 leucine rich repeated containing 1 6p12.2 −2.5 nulliparous promoter RPL10 NM_006013 ribosomal protein L10 Xq28 −2.9 nulliparous promoter BRD9 NM_001009877 bromodomain containing 9 5p15.33 −6.1 nulliparous promoter NUPL2 NM_007342 nucleoporin like 2 7p15 −2.3 nulliparous promoter RPL13 NM_000977 ribosomal protein L13 16q24.3 −3.1 nulliparous promoter EHHADH NM_001966 enoyl-Coenzyme A, hydratase/3-hydroxyacyl 3q26.3-q28 −2.7 Coenzyme A dehydrogenase nulliparous promoter SETD7 NM_030648 SET domain containing (lysine methyltransferase) 7 4q31.1 −3.2 nulliparous promoter BRD3 NM_007371 bromodomain containing 3 9q34 −10.1 nulliparous promoter NME4 NM_005009 non-metastatic cells 4, protein expressed in 16p13.3 −6.3 nulliparous promoter PLD5 NM_152666 phospholipase D family, member 5 1q43 −8.2 nulliparous promoter HEPN1 NM_001037558 HEPACAM opposite strand 1 11q24 −3 nulliparous promoter ORMDL1 NM_016467 ORM1-like 1 (S. cerevisiae) 2q32 −3.5 nulliparous promoter LOC387647 NR_003930 NA NA −4.2 nulliparous promoter TTC15 NM_016030 tetratricopeptide repeat domain 15 2p25.3 −5.1 nulliparous promoter TTC14 NM_133462 tetratricopeptide repeat domain 14 3q27.2 −3.5 nulliparous promoter BMPR2 NM_001204 bone morphogenetic protein receptor, 2q33-q34 −5.8 type II (serine/threonine kinase) nulliparous promoter KPNA1 NM_002264 karyopherin alpha 1 (importin alpha 5) 3q21 −3.5 nulliparous promoter NCAPH NM_015341 non-SMC condensin I complex, subunit H 2q11.2 −2.2 nulliparous promoter ZNF37A NM_003421 zinc finger protein 37A 10p11.2 −3.5 nulliparous promoter METT10D NM_024086 methyltransferase 10 domain containing 17p13.3 −3.2 nulliparous promoter TNR_C6B NM_015088 trinucleotide repeat containing 6B 22q13 −3.1 nulliparous promoter FUNDC2 NM_023934 FUN 14 domain containing 2 Xq28 −4.6 nulliparous promoter LOC283951 NM_001010878 NA NA −2.3 nulliparous promoter YME1L1 NM_014263 YME1-like 1 (S. cerevisiae) 10p14 −5 nulliparous promoter KAT2A NM_021078 K(lysine) acetyltransferase 2A 17q12-q21 −4.1 nulliparous promoter LPCAT3 NM_005768 lysophosphatidylcholine acyltransferase 3 12p13.31 −3.8 nulliparous promoter NPTX2 NM_002523 neuronal pentraxin II 7q21.3-q22.1 −18.6 nulliparous promoter MATR3 NM_018834 matrin 3 5q31.3 −2.5 nulliparous promoter PECI NM_006117 peroxisomal D3,D2-enoyl-CoA isomerase 6p24.3 −2.7 nulliparous promoter ICOSLG NM_015259 inducible T-cell co-stimulator ligand 21q22.3 −3.5 nulliparous promoter SMURF1 NM_181349 SMAD specific E3 ubiquitin protein ligase 1 7q21.1-q31.1 −2.4 nulliparous promoter AP2S1 NM_021575 adaptor-related protein complex 2, sigma 1 subunit 19q13.2-q13.3 −3.2 nulliparous promoter C16orf81 NR_024347 chromosome 16 open reading frame 81 16q24.3 −6 nulliparous promoter PCDHB1 NM_013340 protocadherin beta 1 5q31 −10 nulliparous promoter EGR1 NM_001964 early growth response 1 5q23-q31 −7.5 nulliparous promoter PPM1J NM_005167 protein phosphatase 1J (PP2C domain containing) 1p13.1 −3.1 nulliparous promoter USP43 NM_153210 ubiquitin specific peptidase 43 17p12 −2.3 nulliparous promoter PNPLA3 NM_025225 patatin-like phospholipase domain containing 3 22q13.31 −2.3 nulliparous promoter UNC5B NM_170744 unc-5 homolog B (C. elegans) 10q22.2 −3.3 nulliparous promoter UNC5B NM_170744 unc-5 homolog B (C. elegans) 10q22.2 15.6 nulliparous promoter DNAJB11 NM_016306 DnaJ (Hsp40) homolog, subfamily B, member 11 3q27 −2.7 nulliparous promoter FBLN5 NM_006329 fibulin 5 14q31 −2.6 nulliparous promoter SLC30A5 NM_024055 solute carrier family 30 (zinc transporter), member 5 5q12.1 −2.3 nulliparous promoter SENP6 NM_015571 SUMOI/sentrin specific peptidase 6 6q13-q14.3 −2.5 nulliparous promoter C14orf178 NM_174943 chromosome 14 open reading frame 178 14q24.3 −2.8 nulliparous promoter FNDC3A NM_001079673 fibronectin type III domain containing 3A 13q14.12 −21.1 nulliparous promoter TMEM74 NM_153015 transmembrane protein 74 8q23.1 −8.2 nulliparous promoter NPPC NM_024409 natriuretic peptide precursor C 2q24-qter −2.G nulliparous promoter CISD2 NM_001008388 CDGSH iron sulfur domain 2 4q24 −2.2 nulliparous promoter UBXN2B NM_001077619 UBX domain protein 2B 8q12.1 −12.8 nulliparous promoter RALGPS2 NM_152663 Ral GEF with PH domain and SH3 binding motif 2 1q24 −7 nulliparous promoter SEC13 NM_183352 SEC13 homolog (S. cerevisiae) 3p25-p24 −2.9 nulliparous promoter FAM86C NM_001099653 family with sequence similarity 86, member C 11q13.4 −8.3 nulliparous promoter FAM86D NR_024241 family with sequence similaiity 86, member D 3p12.3 −3.7 nulliparous promoter ZNF581 NM_016535 zinc finger protein 581 19 −2.1 nulliparous promoter HERC3 NM_014606 hect domain and RLD 3 4q21 −3 nulliparous promoter ABCD3 NM_001122674 ATP-binding cassette, sub-family D (ALD), member 3 1p22-p21 −2.8 nulliparous promoter TP53INP1 NM_001135733 tumor protein p53 inducible nuclear protein 1 8q22 −2.3 nulliparous promoter GPR89B NM_016334 G protein-coupled receptor 89B 1q21.1 −5.4 nulliparous promoter GPR89A NM_001097612 G protein-coupled receptor 89A 1q21.1 −5.4 nulliparous promoter RG9MTD1 NM_017819 RNA (guanine-9-) methyltransferase 3q12.3 −15.6 domain containing 1 nulliparous promoter LMNB2 NM_032737 lamin B2 19p13.3 −5.2 nulliparous promoter SRrp35 NM_080743 NA NA −8.1 nulliparous promoter MRPS23 NM_016070 mitochondrial ribosomal protein S23 17q22-q23 −2.7 nulliparous promoter INSM1 NM_002196 insulinoma-associated 1 20p11.2 −2.6 nulliparous promoter PCDHGA9 NM_032089 protocadherin gamma subfamily A, 9 5q31 38 nulliparous promoter PCDHGA9 NM_032089 protocadherin gamma subfamily A, 9 5q31 −3.5 nulliparous promoter EIF4EBP2 NM_004096 eukaryotic translation initiation factor 4E 10q21q22 3 binding protein 2 nulliparous promoter PHF6 NM_032335 PHD finger protein 6 Xq26 −2.9 nulliparous promoter TESSP1 NM_001135086 NA NA −3.5 nulliparous promoter NXNL2 NM_145283 nucleoredoxin-like 2 9q22.2 −3.5 nulliparous promoter UBE2W NM_018299 ubiquitin-conjugating enzyme E2W (putative) 8q21.11 −12.7 nulliparous promoter FGF21 NM_019113 fibroblast growth factor 21 19q13.1-qter −5.5 nulliparous promoter NADK NM_023018 NAD kinase 1p36.33 −7.2 nulliparous promoter VMAC NM_001017921 vimentin-type intermediate filament 19p13.3 −5.4 associated coiled-coil protein nulliparous promoter VSTM2L NM_080607 V-set and transmembrane domain containing 2 like 20q11.23 −2.6 nulliparous promoter PF4V1 NM_002620 platelet factor 4 variant 1 4q12-q21 −4.9 nulliparous promoter MYO1C NM_033375 myosin IC 17p13.3 −4.2 nulliparous promoter B3GNT9 NM_033309 UDP-GlcNAc:betaGal 16q22.1 −4.3 beta-1,3-N-acetylglucosaminyl transferase 9 11p11.2 −5.4 nulliparous promoter CHST1 NM_003654 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 9q34 −3.6 nulliparous promoter ADAMTS13 NM_139027 ADAM metallopeptidase with thrombospondin type 1 motif, 13 22q11.2-qter −3.3 nulliparous promoter FBXO7 NM_001033024 F-box protein 7 19q13.3 −14 nulliparous promoter KCNA7 NM_031886 potassium voltage-gated channel, shaker-related subfamily, member 7 20q13 −22.1 nulliparous promoter BCAS4 NM_198799 breast carcinoma amplified sequence 4 1q25.1 −9.1 nulliparous promoter SNORD81 NR_003938 small nucleolar RNA, C/D box 81 1q25.1 −9.1 nulliparous promoter SNORD80 NR_003940 small nucleolar RNA, C/D box 80 NA −5.3 nulliparous promoter FAM62B NM_020728 NA NA −2.5 nulliparous promoter FAM62C NM_031913 NA NA 44.8 nulliparous promoter FAM62C NM_031913 NA 15q13.1 −3.8 nulliparous promoter PGBD4 NM_152595 piggyBac transposable element derived 4 2q32.2-q32.3 −31.2 nulliparous promoter STAT1 NM_007315 signal transducer and activator of transcription 1, 91 kDa 17p12-p11 −2.7 nulliparous promoter CHRNB1 NM_000747 cholinergic receptor, nicotinic, beta 1 (muscle) 6q23.2 −2.5 nulliparous promoter FAM54A NM_138419 family with sequence similarity 54, member A 8q24.13 −4.4 nulliparous promoter ZHX1 NM_007222 zinc fingers and homeoboxes 1 10p12.1 −5 nulliparous promoter MASTL NM_032844 microtubule associated serine/threonine kinase-like 11q24 −5.2 nulliparous promoter SIAE NM_170601 sialic acid acetylesterase 13q34 −2.4 nulliparous promoter ING1 NM_198217 inhibitor of growth family, member 1 14q23 −3 nulliparous promoter PSMA3 NM_002788 proteasome (prosome, macropain) subunit, alpha type, 3 NA −3.7 nulliparous promoter LOC100131726 NR_024479 NA 13q21 −3.3 nulliparous promoter ATXN8OS NR_002717 ATXN8 opposite strand (non-protein coding) 11q13 −2.2 nulliparous promoter FTH1 NM_002032 ferritin, heavy polypeptide 1 1q21.2 −5.3 nulliparous promoter HIST2H2AA4 NM_001040874 histone cluster 2, H2aa4 22q13.2-q13.31 −6 nulliparous promoter NDUFA6 NM_002490 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14 kDa 16q22.1 −8.9 nulliparous promoter ZDHHC1 NM_013304 zinc finger, DHHC-type containing 1 10q22 −3.8 nulliparous promoter RPS24 NM_001026 rlbosomal protein S24 4q34.1 −2.4 nulliparous promoter GALNTL6 NM_001034845 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6 8q24.3 −6.4 nulliparous promoter PTP4A3 NM_032611 protein tyrosine phosphatase type IVA, member 3 8q22.3 −4.5 nulliparous promoter FBXO43 NM_001077528 F-box protein 43 Xp22.13 −3.3 nulliparous promoter GPR64 NM_001079859 G protein-coupled receptor 64 11q23.3 −3.9 nulliparous promoter THY1 NM_006288 Thy-1 cell surface antigen 16q12.1 −3.7 nulliparous promoter SALL1 NM_002968 sal-like 1 (Drosophila) 12q13.2 −9.6 nulliparous promoter CS NM_004077 citrate synthase 7q31.3 −4.8 nulliparous promoter FSCN3 NM_020369 (ascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus) 12q22-q23.1 −4.5 nulliparous promoter NT5DC3 NM_016575 5′-nucleotidase domain containing 3 6q22.31 −2.2 nulliparous promoter NT5DC1 NM_152729 5′-nucleotidase domain containing 1 2q24-q31 −5.3 nulliparous promoter LRP2 NM_004525 low density lipoprotein-related protein 2 10q25.1 −26.3 nulliparous promoter C10orf78 NM_145247 chromosome 10 open reading frame 78 3p21.3 −5.9 nulliparous promoter RPSA NM_002295 ribosomal protein SA 11q13.4 −2.6 nulliparous promoter LRP5 NM_002335 low density lipoprotein receptor-related protein 5 2p22.2 −6.4 nulliparous promoter C2orf56 NM_144736 chromosome 2 open reading frame 56 12p12.1 −3.4 nulliparous promoter KCNJ8 NM_004982 potassium inwardly-rectifying channel, subfamily J, member 8 12q24.1 −7 nulliparous promoter TDG NM_003211 thymme-DNA glycosylase 6p21.3 −11.8 nulliparous promoter NFYA NM_002505 nuclear transcription factor Y, alpha 5p13.2 −5.9 nulliparous promoter C5orf33 NM_001085411 chromosome 5 open reading frame 33 13q32.3 −11.1 nulliparous promoter TMTC4 NM_001079669 transmembrane and tetratricopeptide repeat containing 4 6q23.2 −4.6 nulliparous promoter SLC35D3 NM_001008783 solute carrier family 35, member D3 1p32 −11.8 nulliparous promoter PPIE NM_006112 peptidylprolyl isomerase E (cyclophilin E) 7q36 −6 nulliparous promoter RHEB NM_005614 Ras homolog enriched in brain 3p25.1 −5.9 nulliparous promoter TRNT1 NM_182916 tRNA nucleolidyl transferase, CCA-adding, 1 9q34.3 −2.6 nulliparous promoter CAMSAP1 NM_015447 calmodulin regulated spectnn-associated protein 1 7q11.23 −2.2 nulliparous promoter TRIM73 NM_198924 tripartite motif-containing 73 7q34 −7.1 nulliparous promoter JHDM1D NM_030647 jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) 10q24.31 −4 nulliparous promoter CUTC NM_015960 cutC copper transporter homolog (E. coli) 11q22 −15 nulliparous promoter BIRC2 NM_001166 baculoviral IAP repeat-containing 2 12q13.11 −4.9 nulliparous promoter RPAP3 NM_024604 RNA polymerase II associated protein 3 7q22 −2.1 nulliparous promoter MOSPD3 NM_001040097 motile sperm domain containing 3 10q22.3 −4.8 nulliparous promoter BMPR1A NM_004329 bone morphogenetic protein receptor, type IA 2q24.2 −5.8 nulliparous promoter RBMS1 NM_002897 RNA binding motif, single stranded interacting protein 1 2q24.2 −9.5 nulliparous promoter RBMS1 NM_002897 RNA binding motif, single stranded interacting protein 1 6q23.2 −2.3 nulliparous promoter MAP7 NM_003980 microtubule-associated protein 7 9p13.1 −2.5 nulliparous promoter GNE NM_005476 glucosamine (UDP-N-acetyt)-2-epimerase/N-acetylmannosamine kinase 19q13.41 −17.9 nulliparous promoter ZNF813 NM_001004301 zinc finger protein 813 4q21.1-q21.21 −18.4 nulliparous promoter ANKRD17 NM_032217 ankyrin repeat domain 17 16q22.2 −2.9 nulliparous promoter TXNL4B NM_017853 thioredoxin-like 4B NA −5.9 nulliparous promoter FLJ46082 NM_207417 NA 17 −2.5 nulliparous promoter PPP1R1B NM_032192 protein phosphatase 1, regulatory (inhibitor) subunit 1B 1p35 −2.2 nulliparous promoter RNU11 NR_004407 RNA, U11 small nuclear 8p21 −3.3 nulliparous promoter NEFL NM_006158 neurofilament, light polypeptide 5q31 −4.1 nulliparous promoter PCDHGA10 NM_032090 protocadhenn gamma subfamily A, 10 4q32.3 −2.1 nulliparous promoter TMEM192 NM_001100389 transmembrane protein 192 21q22.2 −2.1 nulliparous promoter CBR3 NM_001236 carbonyl reductase 3 3q28 −7.5 nulliparous promoter SST NM_001048 somatostatin 3p25.3-P25.2 −2.5 nulliparous promoter ATG7 NM_001136031 ATG7 autophagy related 7 homolog (S. cerevisiae) 3q23 −2.4 nulliparous promoter CLSTN2 NM_022131 calsyntemn 2 4q27 −7.4 nulliparous promoter ANXA5 NM_001154 annexin A5 17q23.2 −4.8 nulliparous promoter MSI2 NM_138962 musashi homolog 2 (Drosophila) 17p12-p11.2 −2.9 nulliparous promoter PIGL NM_004278 phosphatidylinositol glycan anchor biosynthesis, class L 17q21 −4.1 nulliparous promoter HSPB9 NM_033194 heat shock protein, alpha-crystallin-related, B9 21q22.2 −2.2 nulliparous promoter PIGP NM_153681 phosphatidylinositol glycan anchor biosynthesis, class P 16p13.3 −7.7 nulliparous promoter PIGQ NM_148920 phosphatidylinositol glycan anchor biosynthesis, class Q 1p21 −2.7 nulliparous promoter GCLM NM_002061 glutamate-cysteine ligase, modifier subunit 22q13.1 −3.3 nulliparous promoter GTPBP1 NM_004286 GTP binding protein 1 2q24.3 −3.6 nulliparous promoter STK39 NM_013233 serine threonine kinase 39 (STE20/SPS1 homolog, yeast) 8q24 −3.2 nulliparous promoter RNF139 NM_007218 ring finger protein 139 3q29 −4.4 nulliparous promoter PIGZ NM_025163 phosphatidylinositol glycan anchor biosynthesis, class Z 14q11.2 −6.8 nulliparous promoter THTPA NM_001126339 thiamine triphosphatase 7q21.13 −2.8 nulliparous promoter ZNF804B NM_181646 zinc finger protein 804B 6p21.1 −11.8 nulliparous promoter C6orf130 NM_145063 chromosome 6 open reading frame 130 15q25.2 −24.5 nulliparous promoter FAM154B NM_001008226 family with sequence similarity 154, member B 5q31 −2.1 nulliparous promoter PCDHA8 NM_031856 protocadherin alpha 8 5q31 −2.1 nulliparous promoter PCDHA9 NM_014005 protocadherin alpha 9 1p22 −3.9 nulliparous promoter FAM69A NM_001006605 family with sequence similarity 69, member A 5q34-q35 −2.8 nulliparous promoter DRD1 NM_000794 dopamine receptor D1 2q31.1 −3.9 nulliparous promoter PDK1 NM_002610 pyruvate dehydrogenase kinase, isozyme 1 7p13 −2.6 nulliparous promoter PURB NM_033224 purine-rich element binding protein B 3q12.1 −4.4 nulliparous promoter C3orf26 NM_032359 chromosome 3 open reading frame 26 4q21.2 −3.5 nulliparous promoter KLHL2 NM_007246 kelch-like 2, Mayven (Drosophila) 19p13.2 −2.1 nulliparous promoter ILF3 NM_001137673 interleukin enhancer binding factor 3, 90 kDa 10p15.1 −6.2 nulliparous promoter ASB13 NM_024701 ankyrin repeat and SOCS box-containing 13 13q12.2 −4.3 nulliparous promoter CDX2 NM_001265 caudal type homeobox 2 13q12.2 5.6 nulliparous promoter CDX2 NM_001265 caudal type homeobox 2 3q27 −2.2 nulliparous promoter MCF2L2 NM_015078 MCF.2 cell line derived transforming sequence-like 2 16q24.3 −2.2 nulliparous promoter AFG3L1 NR_003226 AFG3 ATPase family gene 3-like 1 (S. cerevisiae) 8q11.21 −3.3 nulliparous promoter KIAA0146 NM_001080394 KIAA0146 5q31 −3.5 nulliparous promoter PCDHGB6 NM_032100 protocadherin gamma subfamily B, 6 5q31 −4.1 nulliparous promoter PCDHGB6 NM_032100 protocadherin gamma subfamily B, 6 5p15 −3 nulliparous promoter POLS NM_006999 polymerase (DNA directed) sigma 3p21.2 −7 nulliparous promoter WDR82 NM_025222 WD repeat domain 82 19q13.2 −4.5 nulliparous promoter TTC9B NM_152479 tetratricopeptide repeat domain 9B 4p16.3 −4.7 nulliparous promoter ZNF141 NM_003441 zinc finger protein 141 4p16.3 −4.6 nulliparous promoter ABCA11P NR_002451 ATP-binding cassette, sub-family A (ABC1), member 11 (pseudogene) 14q13.2 −28.4 nulliparous promoter MBIP NM_016586 MAP3K12 binding inhibitory protein 1 10q22 −2.4 nulliparous promoter NDST2 NM_003635 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 2q31 −2.5 nulliparous promoter CYBRD1 NM_024843 cytochrome b reductase 1 7q11.23 −2.8 nulliparous promoter SBDSP NR_024109 Shwachman-Bodian-Diamond syndrome pseudoqene 14q23.1 −3.3 nulliparous promoter TOMM20L NM_207377 translocase of outer mitochondrial membrane 20 homolog (yeast)-like NA −2.5 nulliparous promoter EVI1 NM_001105077 NA 19q13.42 −2.7 nulliparous promoter ZNF787 NM_001002836 zinc finger protein 787 16p11.2 −2.2 nulliparous promoter ZNF785 NM_152458 zinc finger protein 785 19q13.42 −2.8 nulliparous promoter ZNF784 NM_203374 zinc finger protein 784 9q34.11 −2.8 nulliparous promoter TTLL11 NM_001139442 tubulin tyrosine ligase-like family, member 11 20q11.23 −2.1 nulliparous promoter PPP1R16B NM_015568 protein phosphatase 1, regulatory (inhibitor) subunit 16B 1p34 −3.6 nulliparous promoter EDN2 NM_001956 endothelin 2 12q24.33 −4.7 nulliparous promoter EP400NL NR_003290 EP400 N-terminal like 19q13.1 −3.2 nulliparous promoter ZFP36 NM_003407 zinc finger protein 36, C3H type, homoloq (mouse) 12q24.1 −3.8 nulliparous promoter ISCU NM_213595 iron-sulfur cluster scaffold homolog (E. coli) 16p13.13 −5 nulliparous promoter TXNDC11 NM_015914 thioredoxin domain containing 11 1p13.2 −3.1 nulliparous promoter FAM19A3 NM_001004440 (amily with sequence similarity 19 (chemokine (C-C motif)-like), member A3 12q15-q21 −9.5 nulliparous promoter TRHDE NM_013381 thyrotropin-releasing hormone degrading enzyme 2p13 −5.2 nulliparous promoter HK2 NM_000189 hexokinase 2 10q21-q24 −5.6 nulliparous promoter HTR7 NM_019860 5-hydroxytryptamine (serotonin) receptor 7 (adenylate cydase-coupled) 6p23-p22.3 −2.4 nulliparous promoter MYLIP NM_013262 myosin regulatory light chain interacting protein 20 −4.7 nulliparous promoter RAE1 NM_003610 RAE1 RNA export 1 homolog (S. pombe) 13q21 −3.3 nulliparous promoter KLHL1 NM_020866 kelch-like 1 (Drosophila) 2q31-q33 −3.5 nulliparous promoter PMS1 NM_001128143 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 5q35.2 −9.7 nulliparous promoter MSX2 NM_002449 msh homeobox 2 1q42.2 −2.5 nulliparous promoter C1orf31 NM_001012985 chromosome 1 open reading frame 31 11q21 −16.4 nulliparous promoter CCDC82 NM_024725 coiled-coil domain containing 82 16q22.2 −5.7 nulliparous promoter FTSJD1 NM_018348 FtsJ methyltransferase domain containing 1 7p22.2 −2.1 nulliparous promoter RSPH10B NM_173565 radial spoke head 10 homolog B (Chlamydomonas) 3q26.31 −8.8 nulliparous promoter TNIK NM_015028 TRAF2 and NCK interacting kinase 4q23 −2.1 nulliparous promoter H2AFZ NM_002106 H2A histone family, member Z 5q31.1-q31.3 −2.9 nulliparous promoter GFRA3 NM_001496 GDNF family receptor alpha 3 12q24.3 −3.2 nulliparous promoter UBC NM_021009 ubiquitin C 6q25.3 −4.5 nulliparous promoter SERAC1 NM_032861 serine active site containing 1 19 −2.9 nulliparous promoter ZNF564 NM_144976 zinc finger protein 564 7p22.1 −2.1 nulliparous promoter RSPH10B2 NM_001099697 radial spoke head 10 homolog B2 (Chlamydomonas) 12q13.13 −2.7 nulliparous promoter HOXC9 NM_006897 homeobox C9 NA −6.6 nulliparous promoter LOC100125556 NR_024250 NA 17p11.2 −3.2 nulliparous promoter RASD1 NM_016084 RAS, dexamethasone-induced 1 4q31 −8 nulliparous promoter NR3C2 NM_000901 nudear receptor subfamily 3, group C, member 2 10q11.1 −3.9 nulliparous promoter RASSF4 NM_032023 Ras association (RalGDS/AF-6) domain family member 4 2p13 −2.4 nulliparous promoter EGR4 NM_001965 early growth response 4 8p21.2 −4.2 nulliparous promoter SLC25A37 NM_016612 solute carrier family 25, member 37 12q13.13 −3 nulliparous promoter SPRYD3 NM_032840 SPRY domain containing 3 1p36 −3.7 nulliparous promoter SSU72 NM_014188 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) 19q13.32 −2.2 nulliparous promoter EML2 NM_012155 echinoderm microtubule associated protein like 2 7q31-q35 −3.4 nulliparous promoter LRRC61 NM_023942 leucine rich repeat containing 61 1q32.1 −4 nulliparous promoter NUCKS1 NM_022731 nuclear casein kinase and cyclin-dependent kinase substrate 1 7q32.3 −20.1 nulliparous promoter FAM40B NM_001134336 family with sequence similarity 40, member B 12q12 −4.6 nulliparous promoter TMEM117 NM_032256 transmembrane protein 117 11pi3 −13.1 nulliparous promoter PDHX NM_001135024 pyruvate dehydrogenase complex, component X 7 −4.1 nulliparous promoter C7orf36 NM_020192 chromosome 7 open reading frame 36 12q12 −3.1 nulliparous promoter LRRK2 NM_198578 leucine-rich repeat kinase 2 20q12 −17.4 nulliparous promoter CHD6 NM_032221 chromodomain helicase DNA binding protein 6 5q13 −13.8 nulliparous promoter THBS4 NM_003248 thrombospondin 4 2p24.1 −3.7 nulliparous promoter ASXL2 NM_018263 additional sex combs like 2 (Drosophila) 3p25.2 −4.6 nulliparous promoter SNORA7A NR_002582 small nucleolar RNA, H/ACA box 7A Xp21.1 −2.1 nulliparous promoter LANCL3 NM_198511 LanC lantibiotic synthetase component C-like 3 (bacterial) 4q31.3-q33 −2.9 nulliparous promoter GUCY1A3 NM_001130686 guanylate cyclase 1, soluble, alpha 3 19q13.2-q13.4 −2.8 nulliparous promoter PVRL2 NM_002856 poliovirus receptor-related 2 (herpesvirus entry mediator B) NA −4.6 nulliparous promoter LOC728554 NR_003615 NA Xq23 −2.5 nulliparous promoter ZBTB33 NM_006777 zinc finger and BTB domain containing 33 11q22.3 −2.3 nulliparous promoter PTS NM_000317 6-pyruvoyltetrahydropterin synthase 1q24.2 −9.1 nulliparous promoter ZBTB37 NM_032522 zinc finger and BTB domain containing 37 17q21 −12 nulliparous promoter C1QL1 NM_006688 complement component 1, q subcomponent-like 1 17q25.3 −2.1 nulliparous promoter SIRT7 NM_016538 sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae) 3q13.2- −3.2 nulliparous promoter LSAMP NM_002338 limbic system-associated membrane protein 21q22.2 −2.2 nulliparous promoter TTC3 NM_001001894 tetratricopeptide repeat domain 3 22q12.1 −2.9 nulliparous promoter MN1 NM_002430 meningioma (disrupted in balanced (ranslocation) 1 2p21 −7.9 nulliparous promoter RHOQ NM_012249 ras homolog gene family, member Q 3q22.2-q22.3 −3.1 nulliparous promoter STAG1 NM_005862 stromal antigen 1 4q31.3 −2.3 nulliparous promoter GLRB NM_000824 glycine receptor, beta 19q13.12 −2.2 nulliparous promoter ANKRD27 NM_032139 ankyrin repeat domain 27 (VPS9 domain) 1p33-p32.1 −2.1 nulliparous promoter YIPF1 NM_018982 Yip1 domain family, member 1 6p22.1 −8.2 nulliparous promoter HIST1H2BC NM_003526 histone cluster 1, H2bc 12q24.11 −3.8 nulliparous promoter SART3 NM_014706 squamous cell carcinoma antigen recognized by T cells 3 11p15.1 −5.3 nulliparous promoter NELL1 NM_006157 NEL-like 1 (chicken) 4q21 −2.4 nulliparous promoter FGF5 NM_004464 fibroblast growth factor 5 11q13.3 −3.4 nulliparous promoter FGF4 NM_002007 fibroblast growth factor 4 8q22 −4.5 nulliparous promoter POLR2K NM_005034 polymerase (RNA) II (DNA directed) polypeptide K, 7.0 kDa Xq28 −2.9 nulliparous promoter SNORA70 NR_000011 small nucleolar RNA, H/ACA box 70 5q35.2 −3 nulliparous promoter CPLX2 NM_006650 complexin 2 17 −3.1 nulliparous promoter PLSCR3 NM_020360 phospholipid scramblase 3 1q32.1 −2.7 nulliparous promoter CR1L NM_175710 complement component (3b/4b) receptor 1-like 1q41 −2.2 nulliparous promoter SUSD4 NM_017982 sushi domain containing 4 8p12 −2.5 nulliparous promoter RBPMS NM_001008712 RNA binding protein with multiple splicing 6p22.3 −3.4 nulliparous promoter RBM24 NM_153020 RNA binding motif protein 24 22q13.1 −2.6 nulliparous promoter MGAT3 NM_002409 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyl transferase 20q13.12 −2.7 nulliparous promoter TOX2 NM_001098797 TOX high mobility group box family member 2 4q21.22 −5.6 nulliparous promoter LIN54 NM_001115008 lin-54 homolog (C. elegans) 13q14.11 −5.3 nulliparous promoter KIAA0564 NM_015058 KIAA0564 6q21 −2.7 nulliparous promoter NR2E1 NM_003269 nuclear receptor subfamily 2, group E, member 1 2q −3.8 nulliparous promoter AGPS NM_003659 alkylglycerone phosphate synthase 16q22 −5.8 nulliparous promoter ACD NM_001082486 adrenocortical dysplasia homolog (mouse) Xq22 −3.3 nulliparous promoter XKRX NM_212559 XK, Kell blood group complex subunit-related, X-linked 2q24.2 −2.8 nulliparous promoter CD302 NM_014880 CD302 molecule 3q29 −2.4 nulliparous promoter FYTTD1 NM_001011537 forty-two-three domain containing 1 Xp11.23 −4.2 nulliparous promoter GPKOW NM_015698 G patch domain and KOW motifs 21q21 −3 nulliparous promoter NCAM2 NM_004540 neural cell adhesion molecule 2 7q21 −2.5 nulliparous promoter FZD1 NM_003505 frizzled homolog 1 (Drosophila) 5q13.1 −3.9 nulliparous promoter TNPO1 NM_002270 transportin 1 15q13.1 −3.8 nulliparous promoter AVEN NM_020371 apoptosis, caspase activation inhibitor 19q13.42 −2.1 nulliparous promoter CCDC106 NM_013301 coiled-coil domain containing 106 4q12 −7.9 nulliparous promoter SGCB NM_000232 sarcoglycan, beta (43 kDa dystrophin-associated glycoprotein) 8q13.2 −12.7 nulliparous promoter KCNB2 NM_004770 potassium voltage-gated channel, Shab-related subfamily, member 2 11q24.2 −5.2 nulliparous promoter SPA17 NM_017425 sperm autoantigemc protein 17 10q11.23 −3.1 nulliparous promoter C10orf72 NM_001031746 chromosome 10 open reading frame 72 5q34 −3.4 nulliparous promoter FGF18 NM_003862 fibroblast growth factor 18 6q14 −6.8 nulliparous promoter PHIP NM_017934 pleckstrin homology domain interacting protein 9q34.3 −5.9 nulliparous promoter TTF1 NM_007344 transcription termination factor, RNA polymerase I 10q21.3 −25.7 nulliparous promoter REEP3 NM_001001330 receptor accessory protein 3 1q32 −9.8 nulliparous promoter CD55 NM_001114752 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3q23 −7.2 nulliparous promoter PAQR9 NM_198504 progestin and adipoQ receptor family member IX 20q13.2 −2.8 nulliparous promoter PFDN4 NM_002623 prefoldin subunit 4 2p23.2 −2.9 nulliparous promoter DTNB NM_021907 dystrobrevin, beta 22q13.1 −19.3 nulliparous promoter GCAT NM_014291 glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A liqase) 19q13.31 −8.1 nulliparous promoter HNRNPUL1 NM_144732 heterogeneous nuclear ribonucleoprotein U-like 1 10q11.22 −6.2 nulliparous promoter ZNF488 NM_153034 zinc finger protein 488 11q25 −2.5 nulliparous promoter GLB1L2 NM_138342 galactosidase, beta 1-like 2 1q21.2 −5.3 nulliparous promoter HIST2H2AA3 NM_003516 histone cluster 2, H2aa3 18p11.3 −4.1 nulliparous promoter EMILIN2 NM_032048 elastin microfibril Interfacer 2 7p11.2 −4.1 nulliparous promoter PSPH NM_004577 phosphosenne phosphatase 4q21-q23 −2.3 nulliparous promoter PKD2 NM_000297 polycystic kidney disease 2 (autosomal dominant) 13q22.3 −4.7 nulliparous promoter SLAIN1 NM_001040153 SLAIN motif family, member 1 14q32.13 −2.3 nulliparous promoter RIN3 NM_024832 Ras and Rab interactor 3 22q13.2 −7.7 nulliparous promoter SREBF2 NM_004599 sterol regulatory element binding transcription factor 2 17q11.2 −6.7 nulliparous promoter STAT5B NM_012448 signal transducer and activator of transcription 5B 16p13.3 −6.3 nulliparous promoter DECR2 NM_020664 2,4-dienoyl CoA reductase 2, peroxisomal 1p34 −2.8 nulliparous promoter HIVEP3 NM_024503 human immunodeficiency virus type I enhancer binding protein 3 NA −2.8 nulliparous promoter MGC33894 NM_152914 NA 15q22.31 −2.4 nulliparous promoter CLPX NM_006660 CIpX caseinolytic peptidase X homoloq (E. coli) 7q35 −9.2 nulliparous promoter FAM115A NM_014719 family with sequence similarity 115, member A 18q21.1 −3.4 nulliparous promoter HDHD2 NM_032124 haloacid dehalogenase-like hydrolase domain containing 2 NA −3 nulliparous promoter ATPBD3 NM_145232 NA 6q16.2 −2.8 nulliparous promoter MANEA NM_024641 mannosidase, endo-alpha 19p13.2 −3.5 nulliparous promoter JUND NM_005354 jun D proto-oncogene 17q21.32 −2.9 nulliparous promoter HOXB5 NM_002147 homeobox B5 17q21.32 13.8 nulliparous promoter HOXB5 NM_002147 homeobox B5 19q13.11 −2.2 nulliparous promoter RGS9BP NM_207391 regulator of G protein signaling 9 binding protein 15q2 −3.4 nulliparous promoter ADAM10 NM_001110 ADAM metallopeptidase domain 10 11q22.3 −2.2 nulliparous promoter ZC3H12C NM_033390 zinc finger CCCH-type containing 12C 4q21.3 −6.5 nulliparous promoter SEC31A NM_014933 SEC31 homolog A (S. cerevisiae) 6p22.1 −3.7 nulliparous promoter HIST1H2AB NM_003513 histone cluster 1, H2ab 20pter-q11.23 −4.5 nulliparous promoter ANKRD5 NM_022096 ankyrin repeat domain 5 NA −2.6 nulliparous promoter FAM44A NM_148894 NA 2q37.1 −16.1 nulliparous promoter HJURP NM_018410 Holliday junction recognition protein nulliparous promoter KCNK5 NM_003740 potassium channel, subfamily K, member 5 6p21 −8.7 nulliparous promoter SVEP1 NM_153366 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 9q31-q32 −2.6 nulliparous promoter PLCXD2 NM_153268 phosphatidylinositol-specific phospholipase C, X domain containing 2 3q13.2 −2.2 nulliparous promoter RPS19BP1 NM_194326 ribosomal protein S19 binding protein 1 22q13.1 −6 nulliparous promoter CEP97 NM_024548 centrosomal protein 97 kDa 3q12.3 −8.6 nulliparous promoter MERTK NM_006343 c-mer proto-oncogene tyrosine kinase 2q14.1 −10 nulliparous promoter MERTK NM_006343 c-mer proto-oncogene tyrosine kinase 2q14.1 6.2 nulliparous promoter LOC147727 NR_024333 NA NA −2.1 nulliparous promoter MPPE1 NM_023075 metallophosphoesterase 1 18p11.21 −2.6 nulliparous promoter DAPK3 NM_001348 death-associated protein kinase 3 19p13.3 −2.5 nulliparous promoter DGKD NM_152879 diacylglycerol kinase, delta 130 kDa 2q37 −2.5 nulliparous promoter DGKD NM_152879 diacylglycerol kinase, delta 130 kDa 2q37 −6.2 nulliparous promoter TSSC1 NM_003310 tumor suppressing subtransferable candidate 1 2p25.3 −5.1 nulliparous promoter KCNJ12 NM_021012 potassium inwardly-rectifying channel, subfamily J, member 12 17p11.1 −3.7 nulliparous promoter NCOR1 NM_006311 nuclear receptor co-repressor 1 17p11.2 −2.9 nulliparous promoter HIST1H2AC NM_003512 histone cluster 1, H2ac 6p22.1 −8.2 nulliparous promoter UBAP2 NM_018449 ubiquitin associated protein 2 9p11.2 −4.6 nulliparous promoter C1orf203 NR_024126 chromosome 1 open reading frame 203 1p13.1 −2.1 nulliparous promoter GTF2H5 NM_207118 general transcription factor IIH, polypeptide 5 6q25.3 −4.5 nulliparous promoter UAP1 NM_003115 UDP-N-acteylglucosamine pyrophosphoryiase 1 1q23.2 −5.2 nulliparous promoter RTF1 NM_015138 Rtf1, Paf1RNA polymerase II complex component, homolog (S. cerevisiae) 15q14 −8 nulliparous promoter FBF1 NM_001080542 Fas (TNFRSF6) binding factor 1 17q25.3 −3 nulliparous promoter FOXN4 NM_213596 forkhead box N4 12q24.12 −3 nulliparous promoter RASA2 NM_006506 RAS p21 protein activator 2 3q22-q23 −2.9 nulliparous promoter PCDH8 NM_032949 protocadherin 8 13q21.1 −3.9 nulliparous promoter SEC22B NM_004892 SEC22 veside trafficking protein homolog B (S. cerevisiae) 1q21.1 −5.1 nulliparous promoter RPL38 NM_001035258 ribosomal protein L38 17q25.1 −2.7 nulliparous promoter TMEM22 NM_001097599 transmembrane protein 22 3q22.3 −2.1 nulliparous promoter RNF169 NM_001098638 ring finger protein 169 11q13.4 −2.1 nulliparous promoter RPL32 NM_000994 ribosomal protein L32 3q13.3-q21 −4.6 nulliparous promoter PDCD6IP NM_013374 programmed cell death 6 interacting protein 3p22.3 −6.4 nulliparous promoter NEDD4L NM_015277 neural precursor cell expressed, developmentally down-regulated 4-like 18q21 −6 nulliparous promoter LGALS8 NM_201544 lectin, galactoside-binding, soluble, 8 1q43 −2.2 nulliparous promoter FAM130A1 NM_030809 NA NA −2.1 nulliparous promoter PDPK1 NM_002613 3-phosphoinositide dependent protein kinase-1 16p13.3 −4.4 nulliparous promoter LOC729355 NM_001099687 NA NA −3.8 parous gene body RNF17 NM_031277 ring finger protein 17 13q12.13 3.7 parous gene body TFAP2E NM_178548 transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon) 1p34.3 7.9 parous gene body PCDHGB1 NM_032095 protocadherin gamma subfamily B, 1 5q31 9.6 parous gene body IKBKG NM_001099856 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma Xq28 2.5 parous gene body FBP2 NM_003837 fructose-1,6-bisphosphatase 2 9q22.3 9.6 parous gene body A2BP1 NM_018723 NA NA 3.7 parous gene body A2BP1 NM_018723 NA NA −3.5 parous gene body RREB1 NM_001003699 ras responsive element binding protein 1 6p25 −5.4 parous gene body RREB1 NM_001003699 ras responsive element binding protein 1 6p25 3.8 parous gene body GAPVD1 NM_015635 GTPase activating protein and VPS9 domains 1 9q34.11 9.6 parous gene body LHX3 NM_014564 LIM homeobox 3 9q34.3 6.9 parous gene body PRHOXNB NM_001105577 parahox cluster neighbor 13q12.2 12.3 parous gene body FLJ22536 NR_015410 NA NA 2.9 parous gene body MDH2 NM_005918 malate dehydrogenase 2, NAD (mitochondrial) 7cen-q22 5.2 parous gene body ADAMTS9 NM_182920 ADAM metallopeptidase with thrombospondin type 1 motif, 9 3p14.1 3.4 parous gene body RORB NM_006914 RAR-related orphan receptor B 9q22 11.7 parous gene body MIB2 NM_080875 mindbomb homolog 2 (Drosophila) 1p36.33 4 parous gene body DLGAP3 NM_001080418 discs, large (Drosophila) homolog-associated protein 3 1p35.3-p34.1 11.2 parous gene body ACBD5 NM_145698 acyl-Coenzyme A binding domain containing 5 10p12.1 3.4 parous gene body DLGAP1 NM_004746 discs, large (Drosophila) homolog-associated protein 1 18p11.3 4 parous gene body CCDC13 NM_144719 coiled-coil domain containing 13 3p22.1 5.6 parous gene body MEM NM_152513 meiosis inhibitor 1 22q13.2 6.3 parous gene body GP5 NM_004488 glycoprotein V (platelet) 3q29 7.5 parous gene body PRPSAP2 NM_002767 phosphoribosyl pyrophosphate synthetase-associated protein 2 17p12-p11.2 33.9 parous gene body SCN4B NM_174934 sodium channel, voltage-gated, type IV, beta 11q23.3 17.8 parous gene body NOL12 NM_024313 nucleolar protein 12 22q13.1 3.3 parous gene body OSBPL10 NM_017784 oxysterol binding protein-like 10 3p23 3.4 parous gene body ZNF205 NM_001042428 zinc finger protein 205 16p13.3 3.5 parous gene body C2orf39 NM_145038 chromosome 2 open reading frame 39 2p23.3 5.6 parous gene body DYSF NM_001130978 dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) 2p13.3 2.8 parous gene body SCAMP1 NM_004866 secretory earner membrane protein 1 5q14.1 18.6 parous gene body HMGCL NM_000191 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase 1p36.1-p35 4.4 parous gene body LRRC7 NM_020794 leucine rich repeat containing 7 1p31.1 3.3 parous gene body WNK4 NM_032387 WNK lysine deficient protein kinase 4 17q21-q22 7 parous gene body CRB2 NM_173689 crumbs homolog 2 (Drosophila) 9q33.2 2.4 parous gene body ANXA11 NM_145868 annexin A11 10q22.3 5 parous gene body STK3 NM_006281 serine/threonine kinase 3 (STE20 homolog, yeast) 8q22.2 2.1 parous gene body ARRDC2 NM_001025604 arrestin domain containing 2 19p13.12 6.3 parous gene body KIRREL2 NM_199179 kin of IRRE like 2 (Drosophila) 19q13.13 9.4 parous gene body USP34 NM_014709 ubiquitin specific peptidase 34 2p16.1- 2.6 parous gene body SETD4 NM_017438 SET domain containing 4 21q22.13 5.5 parous gene body ADCY4 NM_139247 adenylate cydase 4 14q11.2 4.2 parous gene body CALN1 NM_001017440 calneuron 1 7q11 2.4 parous gene body VCX2 NM_016378 variable charge, X-linked 2 Xp22.32 3.2 parous gene body HCN1 NM_021072 hyperpolanzation activated cyclic nucleotide-gated potassium channel 1 5p12 8 parous gene body HCN3 NM_020897 hyperpolanzation activated cyclic nucleotide-gated potassium channel 3 1q21.2 11 parous gene body JTV1 NM_006303 NA NA 2.6 parous gene body TM4SF19 NM_138461 transmembrane 4 L six family member 19 3q29 12.9 parous gene body RNF216 NM_207116 ring finger protein 216 7p22.1 2.5 parous gene body GGTA1 NR_003191 glycoprotein, alpha-qalactosyltransferase 1 9q33.2 5.1 parous gene body HSD17B14 NM_016246 hydroxysteroid (17-beta) dehydroqenase 14 19q13.33 36.9 parous gene body DTL NM_016448 dentideless homolog (Drosophila) 1q32 2.9 parous gene body GRIK4 NM_014619 glutamate receptor, ionotropic, kainate 4 1iq 3.9 parous gene body ATP6V1H NM_213620 ATPase, H+ transporting, lysosomal 50/57 kDa, V1 subunit H 8q11.2 6.2 parous gene body FMN2 NM_020066 formin 2 1q43 6.8 parous gene body DNM2 NM_004945 dynamin 2 19p 3.9 parous gene body UBAP2 NM_018449 ubiquitin associated protein 2 9p11.2 2 parous gene body UBAP2 NM_018449 ubiquitin associated protein 2 9p11.2 3.8 parous gene body ESRRB NM_004452 estrogen-related receptor beta 14q24.3 −2.7 parous gene body ESRRB NM_004452 estrogen-related receptor beta 14q24.3 4.3 parous gene body DNAJB13 NM_153614 DnaJ (Hsp40) related, subfamily B, member 13 11q13.3 9.9 parous gene body VSX2 NM_182894 visual system homeobox 2 14q24.3 8.8 parous gene body RNF220 NM_018150 ring finger protein 220 1p34.1 3.2 parous gene body PTPRN2 NM_130843 protein tyrosine phosphatase, receptor type, N polypeptide 2 7q36 7.8 parous gene body GRP NM_002091 gastrin-releasing peptide 18q21.1-q21.32 13.5 parous gene body UNC5B NM_170744 unc-5 homolog B (C. elegans) 10q22.2 15.6 parous gene body ACSF2 NM_025149 acyl-CoA synthetase (amity member 2 17q21.33 9.2 parous gene body STAG1 NM_005862 stromal antigen 1 3q22.2-q22.3 3.7 parous gene body HOXB6 NM_018952 homeobox B6 17q21.32 13.8 parous gene body GTF2IRD1 NM_016328 GTF2I repeat domain containing 1 7q11.23 2.7 parous gene body PAX5 NM_016734 paired box 5 9p13.2 −4.3 parous gene body PAX5 NM_016734 paired box 5 9p13.2 64.2 parous gene body DDN NM_015086 dendrin 12q13 3.9 parous gene body SPEG NM_005876 SPEG complex locus 2q35 3.1 parous gene body ZNF28 NM_006969 zinc finger protein 28 19q13.41 15.4 parous gene body LEPROTL1 NM_015344 leptin receptor overlapping transcript-like 1 8p21 5.5 parous gene body PRDM12 NM_021619 PR domain containing 12 9q33-q34 39 parous gene body EXOC3L NM_178516 exocyst complex component 3-like 16q22.1 25.5 parous gene body CBL NM_005188 Cas-Br-M (murine) ecotropic retroviral transforming sequence 11q23.3-qter 4.8 parous gene body WDR37 NM_014023 WD repeat domain 37 10p15.3 3.7 parous gene body HS3ST3B1 NM_006041 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 17p12 12.5 parous gene body HS3ST3B1 NM_006041 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 17p12 −4 parous gene body GNAL NM_182978 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18p11.22-pi1.21 4.5 parous gene body FBXL20 NM_032875 F-box and leucine-rich repeat protein 20 17q21.2 3.4 parous gene body GAS7 NM_201433 growth arrest-specific 7 17p13.1 3.1 parous gene body HES7 NM_032580 hairy and enhancer of split 7 (Drosophila) 17p13.1 214.5 parous gene body PHOX2A NM_005169 paired-like homeobox 2a 11q13.4 10.5 parous gene body OLFM1 NM_014279 olfactomedin 1 9q34.3 2.3 parous gene body OLFM1 NM_014279 olfactomedin 1 9q34.3 −2.9 parous gene body CSMD1 NM_033225 CUB and Sushi multiple domains 1 8p23.2 18.1 parous gene body TBX4 NM_018488 T-box 4 17q21-q22 2.5 parous gene body GABRA2 NM_000807 gamma-aminobutyric acid (GABA) A receptor, alpha 2 4p12 3 parous gene body PSEN1 NM_007318 presemlin 1 14q24.3 2.1 parous gene body SGCD NM_172244 sarcoglycan, delta (35 kDa dystrophin-associated glycoprotein) 5q33-q34 2.3 parous gene body FLJ45983 NR_024255 NA NA 9 parous gene body PPP1R12C NM_017607 protein phosphatase 1, regulatory (inhibitor) subunit 12C 19q13.42 3.8 parous gene body C22orf30 NM_173566 chromosome 22 open reading frame 30 22q12.2 6.5 parous gene body DAGLA NM_006133 diacylglycerol lipase, alpha 11q12.3 3 parous gene body LYL1 NM_005583 lymphoblastic leukemia derived sequence 1 19p13.2 3.2 parous gene body SIAH2 NM_005067 seven in absentia homolog 2 (Drosophila) 3q25 16.2 parous gene body ADAMTS13 NM_139027 ADAM metallopeptidase with thrombospondin type 1 motif, 13 9q34 5.5 parous gene body GNB1 NM_002074 guanine nucleotide binding protein (G protein), beta polypeptide 1 1p36.33 4.8 parous gene body LOC221710 NM_001135575 NA NA 2.6 parous gene body SALL4 NM_020436 sal-like 4 (Drosophila) 20q13.2 5.7 parous gene body LDLR NM_000527 low density lipoprotein receptor 19p13.3 6.1 parous gene body FU34048 NR_015448 NA NA 111.1 parous gene body GMEB2 NM_012384 glucocorticoid modulatory element binding protein 2 20q13.33 3.9 parous gene body LEF1 NM_001130713 lymphoid enhancer-binding factor 1 4q23-q25 2.8 parous gene body SEMA3B NM_004636 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 3p21.3 6.2 parous gene body GALNT13 NM_052917 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13) 2q24.1 6.5 parous gene body NTN1 NM_004822 netrin 1 17p13-p12 8.4 parous gene body URM1 NM_001135947 ubiquitin related modifier 1 homolog (S. cerevisiae) 9q34.13 3.5 parous gene body ADARB2 NM_018702 adenosine deaminase, RNA-specific, B2 (RED2 homolog rat) 10p15.3 8.7 parous gene body SSTR1 NM_001049 somatostatin receptor 1 14q13 3.5 parous gene body AGPAT3 NM_020132 1-acylglycerol-3-phosphate O-acyltransferase 3 21q22.3 4.2 parous gene body C18orf1 NM_181482 chromosome 18 open reading frame 1 18p11.21 30.1 parous gene body SLC35D2 NM_007001 solute carrier family 35, member D2 9q22.33 16.2 parous gene body PDE4B NM_001037340 phosphodiesterase 4B, cAMP-spedfic (phosphodiesterase E4 dunce homolog, Drosophila) 1p31 10 parous gene body ADAM15 NM_207194 ADAM metallopeptidase domain 15 1q21.3 50.5 parous gene body KRT12 NM_000223 keratin 12 17q11 -q12 14.8 parous gene body LATS1 NM_004690 LATS, large tumor suppressor, homolog 1 (Drosophila) 6q25.1 2.3 parous gene body COG8 NM_032382 component of oligomeric golgi complex 8 16q22.1 13.7 parous gene body GNAZ NM_002073 guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 7.2 parous gene body ABAT NM_020686 4-aminobutyrate aminotransferase 16p13.2 2.8 parous gene body HIST1H2AD NM_021065 histone cluster 1, H2ad 6p22.1 3.2 parous gene body PITX2 NM_153427 paired-like homeodomain 2 4q25 21.9 parous gene body ACACA NM_198836 acetyl-Coenzyme A carboxylase alpha 17q21 11.3 parous gene body PITX1 NM_002653 paired-like homeodomain 1 5q31.1 30.5 parous gene body CASZ1 NM_001079843 castor zinc finger 1 1p36.22 73.3 parous gene body PRKX NM_005044 protein kinase, X-linked Xp22.3 2.6 parous gene body EEA1 NM_003566 early endosome antigen 1 12q22 2.6 parous gene body PLOD3 NM_001084 procollagen-lysine, 2-oxoglutarate 5 dioxyqenase 3 7q36 3.4 parous gene body DGKO NM_001347 diacylglycerol kinase, theta 110 kDa 4p16.3 25.9 parous gene body N-PAC NM_032569 NA NA 15.2 parous gene body SUPT3H NM_003599 suppressor of Ty 3 homolog (S. cerevisiae) 6p21.1-p12.3 3.7 parous gene body GGNBP2 NM_024835 gametogenetin binding protein 2 17q21.1 2.8 parous gene body DOK6 NM_152721 docking protein 6 18q22.2 3.2 parous gene body KCNS1 NM_002251 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1 20q12 4.1 parous gene body PHOSPHO1 NM_178500 phosphatase, orphan 1 17q21.32 37.7 parous gene body EFR3B NM_014971 EFR3 homolog B (S. cerevisiae) 2p24.1 7.2 parous gene body CPT1A NM_001876 carnitine palmitoyltransferase 1A (liver) 11q13.2 2.7 parous gene body SOX2OT NR_004053 SOX2 overlapping transcript (non-protein coding) 3q26.3- 9.6 parous gene body KIAA1303 NM_020761 NA NA 3.3 parous gene body ZBTB4 NM_001128833 zinc finger and BTB domain containing 4 17p13.2 12 parous gene body MSI1 NM_002442 musashi homolog 1 (Drosophila) 12q24 2.5 parous gene body ACAP1 NM_014716 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 17p13.1 110.4 parous gene body RTN3 NM_006054 reticulon 3 11q13 2.4 parous gene body GTPBP5 NM_015666 GTP binding protein 5 (putative) 20q13.33 2.1 parous gene body NR2E1 NM_003269 nuclear receptor subfamily 2, group E, member 1 6q21 7.3 parous gene body GPC6 NM_005708 glypican 6 13q32 4.2 parous gene body VCX NM_013452 variable charge, X-linked Xp22.31 3.2 parous gene body CLTCL1 NM_007098 dathrin, heavy chain-like 1 22q11.2 5.5 parous gene body IPPK NM_022755 inositol 1,3,4,5,6-pentakisphosphate 2-kinase 9q22.31 2.8 parous gene body SAMHD1 NM_015474 SAM domain and HD domain 1 20pter-q12 6.2 parous gene body KDELR3 NM_016657 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 22q13 2.3 parous gene body RTDR1 NM_014433 rhabdoid tumor deletion region qene 1 22q11.2 7.2 parous gene body MAP3K13 NM_004721 mitogen-activated protein kinase kinase kinase 13 3q27 2.3 parous gene body CD163L1 NM_174941 CD 163 molecule-like 1 12p13.31 288.4 parous gene body SFRS11 NM_004768 splicing factor, arginine/serine-rich 11 1p31.1 5.4 parous gene body CDR2 NM_001802 cerebellar degeneration-related protein 2, 62 kDa 16p13.1- 2.3 parous gene body NFIX NM_002501 nuclear factor I/X (CCAAT-binding transcription factor) 19p13.3 3.2 parous gene body POU2F2 NM_002698 POU class 2 homeobox 2 19q13.2 11 nulliparous gene body SND1 NM_014390 staphylococcal nuclease and tudor domain containing 1 7q31.3 −4.5 nulliparous gene body GTF2IP1 NR_002206 general transcription factor Ili, pseudoqene 1 7q11.23 −2.1 nulliparous gene body LTK NM_002344 leukocyte receptor tyrosine kinase 15q15.1-q21.1 −6.7 nulliparous gene body C7orf50 NM_032350 chromosome 7 open reading frame 50 7p22.3 −4.8 nulliparous gene body LOC100130987 NR_024469 NA NA −17.1 nulliparous gene body A2BP1 NM_018723 NA NA 3.7 nulliparous gene body A2BP1 NM_018723 NA NA −3.5 nulliparous gene body RREB1 NM_001003699 ras responsive element binding protein 1 6p25 −5.4 nulliparous gene body RREB1 NM_001003699 ras responsive element binding protein 1 6p25 3.8 nulliparous gene body CACNA1H NM_021098 calcium channel, voltage-dependent, T type, alpha 1H subunit 16p13.3 −2.7 nulliparous gene body SMG6 NM_017575 Smg-6 homolog, nonsense mediated mRNA decay (actor (C. elegans) 17p13.3 −2.1 nulliparous gene body PEBP4 NM_144962 phosphatidylethanolamine-binding protein 4 8p21.3 −2.7 nulliparous gene body NTNG1 NM_014917 netrin G1 1p13.2-p13.1 −9 nulliparous gene body C12orf51 NM_001109662 chromosome 12 open reading frame 51 12q24.13 −2.4 nulliparous gene body PARD6G NM_032510 par-6 partitioning defective 6 homolog gamma (C. elegans) 18q23 −9 nulliparous gene body CACNA1A NM_001127221 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 19p13 −2.2 nulliparous gene body ARHGEF4 NM_015320 Rho guanine nucleotide exchange factor (GEF) 4 2q22 −2.5 nulliparous gene body SLC5A10 NM_152351 solute carrier family 5 (sodium/glucose cotransporter), member 10 17p11.2 −3.8 nulliparous gene body C12orf59 NM_153022 chromosome 12 open reading frame 59 12p13.2 −8 nulliparous gene body SLC12A5 NM_001134771 solute carrier family 12 (potassium-chloride transporter), member 5 20q13.12 −4.4 nulliparous gene body PCSK2 NM_002594 proprotein convertase subtilisin/kexin type 2 20p11.2 −10 nulliparous gene body LOC283951 NM_001010878 NA NA −2.3 nulliparous gene body ZNF787 NM_001002836 zinc finger protein 787 19q13.42 −2.7 nulliparous gene body SPN NM_001030288 sialophorin 16p11.2 −2.3 nulliparous gene body SPTLC1 NM_006415 serine palmitoyltransferase, long chain base subunit 1 9q22.31 −2.1 nulliparous gene body IRX1 NM_024337 iroquois homeobox 1 5p15.33 −2.3 nulliparous gene body ONECUT1 NM_004498 one cut homeobox 1 15q21.3 −2.4 nulliparous gene body LOC145783 NR_015419 NA NA −3.3 nulliparous gene body ZNF43 NM_003423 zinc finger protein 43 19p13.1-p12 −2.4 nulliparous gene body TSC22D1 NM_183422 TSC22 domain family, member 1 13q14 −5.7 nulliparous gene body KCNAB1 NM_172160 potassium voltage-gated channel, shaker-related subfamily, beta member 1 3q26.1 −3.3 nulliparous gene body KCNAB1 NM_172160 potassium voltage-gated channel, shaker-related subfamily, beta member 1 3q26.1 −2.3 nulliparous gene body LOC100093631 NR_003580 NA NA −2.1 nulliparous gene body SSH2 NM_033389 slingshot homolog 2 (Drosophila) 17q11.2 −2.5 nulliparous gene body OPA3 NM_001017989 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 19q13.2-q13.3 −2.7 nulliparous gene body OCA2 NM_000275 oculocutaneous albinism II 15q11.2- −6 nulliparous gene body GATA6 NM_005257 GATA binding protein 6 18q11-q12 −3.1 nulliparous gene body ADRA1D NM_000678 adrenergic, alpha-1D-, receptor 20p13 −3.1 nulliparous gene body FAM172A NM_032042 family with sequence similarity 172, member A 5q15 −5.1 nulliparous gene body HEPN1 NM_001037558 HEPACAM opposite strand 1 11q24 −3 nulliparous gene body PDXDC1 NM_015027 pyndoxal-dependent decarboxylase domain containing 1 16p13.11 −13.1 nulliparous gene body CALD1 NM_033157 caldesmon 1 7q33 −2.4 nulliparous gene body RFX1 NM_002918 regulatory factor X, 1 (influences HLA class II expression) 19p13.1 −6.4 nulliparous gene body 38238 NM_001113491 NA NA −2.4 nulliparous gene body NR1I2 NM_003889 nuclear receptor subfamily 1, group I, member 2 3q12-q13.3 −3.8 nulliparous gene body RUNX1 NM_001754 runt-related transcription factor 1 21q22.3 −8.1 nulliparous gene body UBC NM_021009 ubiquitin C 12q24.3 −3.2 nulliparous gene body PRRX1 NM_006902 paired related homeobox 1 1q24.3 −2.7 nulliparous gene body KLC3 NM_177417 kinesin light chain 3 19q13 −2.5 nulliparous gene body ATP9B NM_198531 ATPase, class II, type 9B 18q23 −5.9 nulliparous gene body LGR6 NM_001017403 leucine-nch repeat-containing G protein-coupled receptor 6 1q32.1 −2.1 nulliparous gene body ST3GAL2 NM_006927 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 16q22.3 −2.4 nulliparous gene body GLIS1 NM_147193 GLIS family zinc finger 1 1p32.3 −3.1 nulliparous gene body KCNQ1OT1 NR_002728 KCNQ1 overlapping transcript 1 (non-protein coding) 11p15.5 −4.9 nulliparous gene body LOC100192378 NR_024360 NA NA −3.6 nulliparous gene body MDGA1 NM_153487 MAM domain containing glycosylphosphatidylinositol anchor 1 6p21 −2.8 nulliparous gene body BAZ2A NM_013449 bromodomam adjacent to zinc finger domain, 2A 12q13.3 −2.5 nulliparous gene body MNX1 NM_005515 motor neuron and pancreas homeobox 1 7q36 −3.6 nulliparous gene body CHIC2 NM_012110 cysteine-rich hydrophobic domain 2 4q11 −6.4 nulliparous gene body TRAP1 NM_016292 TNF receptor-associated protein 1 16p13.3 −2.7 nulliparous gene body TNRC18 NM_001080495 trinucleotide repeat containing 18 7p22.1 −3.2 nulliparous gene body JUN NM_002228 jun oncogene 1p32-p31 −11.1 nulliparous gene body MEOX1 NM_004527 mesenchyme homeobox 1 17q21.31 −2.6 nulliparous gene body TMEM181 NM_020823 transmembrane protein 181 6q25.3 −3.3 nulliparous gene body AKT1S1 NM_032375 AKT1 substrate 1 (proline-rich) 19q13.33 −4.8 nulliparous gene body PIK3R1 NM_181523 phosphomositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 −2.1 nulliparous gene body DIO3 NM_001362 deiodinase, iodothyronme, type III 14q32 −7.7 nulliparous gene body GRM5 NM_000842 glutamate receptor, metabotropic 5 11q14.3 −2.9 nulliparous gene body KCNIP3 NM_013434 Kv channel interacting protein 3, calsenilin 2q21.1 −5.5 nulliparous gene body TCF4 NM_001083962 transcription (actor 4 18q21.1 −2.4 nulliparous gene body TFR2 NM_003227 transferrin receptor 2 7q22 −3.4 nulliparous gene body TFR2 NM_003227 transferrin receptor 2 7q22 −2.2 nulliparous gene body ITGAM NM_000632 integrin, alpha M (complement component 3 receptor 3 subunit) 16p11.2 −4.8 nulliparous gene body POM121 NM_172020 POM121 membrane glycoprotein (rat) 7q11.23 −6.9 nulliparous gene body KCNK15 NM_022358 potassium channel, subfamily K, member 15 20q13.12 −4 nulliparous gene body NLRP7 NM_139176 NLR family, pyrin domain containing 7 19q13.42 −3.1 nulliparous gene body KCNQ1 NM_000218 potassium voltage-gated channel, KQT-like subfamily, member 1 11p15.5 −4.9 nulliparous gene body KCNQ1 NM_000218 potassium voltage-gated channel, KQT-like subfamily, member 1 11p15.5 −3.3 nulliparous gene body PAX5 NM_016734 pared box 5 9p13.2 −4.3 nulliparous gene body PAX5 NM_016734 paired box 5 9p13.2 64.2 nulliparous gene body CUX1 NM_181552 cut-like homeobox 1 7q22.1 −2.1 nulliparous gene body TP53INP1 NM_001135733 tumor protein p53 inducible nuclear protein 1 8q22 −2.3 nulliparous gene body ZMIZ2 NM_031449 zinc finger, MIZ-type containing 2 7p13 −2.1 nulliparous gene body NELL1 NM_006157 NEL-tike 1 (chicken) 11p15.1 −5.3 nulliparous gene body LMO3 NM_001001395 LIM domain only 3 (rhombotin-like 2) 12p13 −3.7 nulliparous gene body ING1 NM_198217 inhibitor of growth family, member 1 13q34 −2.4 nulliparous gene body ANKRD29 NM_173505 ankyrin repeat domain 29 18q11.2 −2.1 nulliparous gene body ZEB2 NM_014795 zinc finger E-box binding homeobox 2 2q22.3 −2.2 nulliparous gene body UBE2K NM_005339 ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) 4p14 −3.7 nulliparous gene body C1Z1 NM_012127 CDKN1A interacting zinc finger protein 1 9q34.1 −2.9 nulliparous gene body ERLIN2 NM_007175 ER lipid raft associated 2 8p11.2 −3.8 nulliparous gene body FLJ36208 NM_176677 NA NA −7.7 nulliparous gene body HLCS NM_000411 holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase) 21q22.1 −3.4 nulliparous gene body LOC646643 NM_001101401 NA NA −6.4 nulliparous gene body CAMKK2 NM_153500 calcium/calmodulin-dependent protein kinase kinase 2, beta 12q24.2 −2.6 nulliparous gene body FTCD NM_006657 formiminotransferase cyclodeaminase 21q22.3 −2.6 nulliparous gene body HECW1 NM_015052 HECT, C2 and WW doman containing E3 ubiquitin protein ligase 1 7p13 −2.4 nulliparous gene body RBM20 NM_001134363 RNA binding motif protein 20 10q25.3 −4.5 nulliparous gene body SHISA3 NM_001080505 shisa homolog 3 (Xenopus laevis) 4p13 −3.8 nulliparous gene body C10orf47 NM_153256 chromosome 10 open reading frame 47 10p14 −4.9 nulliparous gene body BEST2 NM_017682 bestrophin 2 19p13.2-p13.12 −2.6 nulliparous gene body PRDM8 NM_020226 PR domain containing 8 4q21 −2.1 nulliparous gene body OBSCN NM_052843 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 1q42 −3.8 nulliparous gene body HS3ST3B1 NM_006041 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 17p12 12.5 nulliparous gene body HS3ST3B1 NM_006041 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 17p12 −4 nulliparous gene body RASIP1 NM_017805 Ras interacting protein 1 19q13.33 −3.7 nulliparous gene body SORCS1 NM_052918 sortilin-related VPS 10 domain contaming receptor 1 10q23-q25 −5.6 nulliparous gene body SLC32A1 NM_080552 solute carrier family 32 (GABA vesicular transporter), member 1 20q11 −6.7 nulliparous gene body MYO1D NM_015194 myosin ID 17q11-q12 −4.2 nulliparous gene body TMEM161A NM_017814 transmembrane protein 161A 19p13.11 −2.1 nulliparous gene body LOC285205 NR_015394 NA NA −4.6 nulliparous gene body OLFM1 NM_014279 olfactomedin 1 9q34.3 2.3 nulliparous gene body OLFM1 NM_014279 olfactomedin 1 9q34.3 −2.9 nulliparous gene body ADAMTS12 NM_030955 ADAM metallopeptidase with thrombospondin type 1 motif, 12 5q35 −2.6 nulliparous gene body CTNND2 NM_001332 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 5p15.2 −6.2 nulliparous gene body BBC3 NM_014417 BCL2 binding component 3 19q13.3-q13.4 −2.6 nulliparous gene body PIGY NM_001042616 phosphatidylinositol glycan anchor biosynthesis, class Y 4q22.1 −5.1 nulliparous gene body GRASP NM_181711 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 12q −3 nulliparous gene body IGF2R NM_000876 insulin-like growth factor 2 receptor 6q25-q27 −2.9 nulliparous gene body DOCK11 NM_144658 dedicator of cytokinesis 11 Xq24 −2 nulliparous gene body DOCK11 NM_144658 dedicator of cytokinesis 11 Xq24 −2.5 nulliparous gene body LHFPL2 NM_005779 lipoma HMGIC fusion partner-like 2 5q13 −6 nulliparous gene body GPRC5B NM_016235 G protein-coupled receptor, family C, group 5, member B 16p12 −3.9 nulliparous gene body GREB1 NM_014668 growth regulation by estrogen in breast cancer 1 2p25.1 −3 nulliparous gene body NCOA1 NM_147233 nuclear receptor coactivator 1 2p23 −2.8 nulliparous gene body CCDC108 NM_194302 coiled-coil domain containing 108 2q35 −2.1 nulliparous gene body CBLN2 NM_182511 cerebellin 2 precursor 18q22.3 −3.1 nulliparous gene body PBX3 NM_006195 pre-B-cell leukemia homeobox 3 9q33.3 −2.8 nulliparous gene body PCDHB10 NM_018930 protocadherin beta 10 5q31 −7.1 nulliparous gene body FANCC NM_000136 Fanconi anemia, complementation group C 9q22.3 −2.1 nulliparous gene body CDGAP NM_020754 NA NA −7.1 nulliparous gene body PHIP NM_017934 pleckstrin homology domain interacting protein 6q14 −6.8 nulliparous gene body SLC8A1 NM_001112802 solute carrier family 8 (sodium/calcium exchanger), member 1 2p23-p22 −3.1 nulliparous gene body CYBRD1 NM_024843 cytochrome b reductase 1 2q31 −2.5 nulliparous gene body FGF11 NM_004112 fibroblast growth factor 11 17p13.1 −2.7 nulliparous gene body DLC1 NM_182643 deleted in liver cancer 1 8p22 −2.1 nulliparous gene body RANBP3 NM_007320 RAN binding protein 3 19p13.3 −4.9 nulliparous gene body C1orf150 NM_145278 chromosome 1 open reading frame 150 1q44 −4.1 nulliparous gene body EPB41L3 NM_012307 erythrocyte membrane protein band 4.1-like 3 18p11.32 −2.6 nulliparous gene body H1F0 NM_005318 H1 histone family, member 0 22q13.1 −19.3 nulliparous gene body MINA NM_001042533 MYC induced nuclear antigen 3q22.1 −3.1 nulliparous gene body HDLBP NM_005336 high density lipoprotein binding protein 2q37.3 −2.3 nulliparous gene body PPEF2 NM_006239 protein phosphatase, EF-hand calcium binding domain 2 4q21.21 −73.9 nulliparous gene body EGLN1 NM_022051 egl nine homolog 1 (C. elegans) 1q42.1 −2.8 nulliparous gene body COL5A1 NM_000093 collagen, type V, alpha 1 9q34.2-q34.3 −3 nulliparous gene body SH2B2 NM_020979 SH2B adaptor protein 2 7q22.1 −2.7 nulliparous gene body BCOR NM_017745 BCL6 co-repressor Xp11.4 −5.2 nulliparous gene body GRAMD1C NM_017577 GRAM domain containing 1C 3q13.31 −4 nulliparous gene body GRAMD1B NM_020716 GRAM domain containing 1B 11q24.1 −2.5 nulliparous gene body MAPK8IP1 NM_005456 mitogen-activated protein kinase 8 interacting protein 1 11pi1.2 −14.8 nulliparous gene body GIPR NM_000164 gastric inhibitory polypeptide receptor 19q13.2-q13.3 −3.4 nulliparous gene body GPR153 NM_207370 G protein-coupled receptor 153 1p36.31 −3.8 nulliparous gene body BEGAIN NM_020836 brain-enriched guanylate kinase-associated homolog (rat) 14q32.2 −2.1 nulliparous gene body SGK3 NM_001033578 serum/glucocorticoid regulated kinase family, member 3 8q12 −2.5 nulliparous gene body WNT10A NM_025216 wingless-type MMTV integration site family, member 10A 2q35 −3.2 nulliparous gene body LRP5 NM_002335 low density lipoprotein receptor-related protein 5 11q13.4 −2.9 nulliparous gene body IFI6 NM_002038 interferon, alpha-inducible protein 6 1p35 −2.8 nulliparous gene body ACOX1 NM_007292 acyl-Coenzyme A oxidase 1, palmitoyl 17q25.1 −3 nulliparous gene body LMO4 NM_006769 LIM domain only 4 1p22.3 −5.6 nulliparous gene body TEX14 NM_031272 testis expressed 14 17 −4.1 nulliparous gene body SREBF1 NM_001005291 sterol regulatory element binding transcription factor 1 17p11.2 −3.7 nulliparous gene body RILPL1 NM_178314 Rab interacting lysosomal protein-like 1 12q24.31 −3.2 nulliparous gene body MYO16 NM_015011 myosin XVI 13q33.3 −3.7 nulliparous gene body REEP6 NM_138393 receptor accessory protein 6 19p13.3 −2.3 nulliparous gene body HIVEP2 NM_006734 human immunodeficiency virus type I enhancer binding protein 2 6q23-q24 −17.2 nulliparous gene body GNAS NM_016592 GNAS complex locus 20q13.2-q13.3 −2.6 nulliparous gene body PTH1R NM_000316 parathyroid hormone 1 receptor 3p22-p21.1 −3.3 nulliparous gene body PTH1R NM_000316 parathyroid hormone 1 receptor 3p22-p21.1 −2.2 nulliparous gene body PTH1R NM_000316 parathyroid hormone 1 receptor 3p22-p21.1 −2.2 nulliparous gene body SNTB2 NM_006750 syntrophin, beta 2 (dystrophin-associated protein A1, 59 kDa, basic component 2) 16q22.1 −4.3 nulliparous gene body NEURL NM_004210 neuralized homolog (Drosophila) 10q25.1 −6.4 nulliparous gene body CHMP4B NM_176812 chromatin modifying protein 4B 20q11.22 −3.8 nulliparous gene body PHF19 NM_015651 PHD finger protein 19 9q34.11 −5.3 nulliparous gene body ZNF497 NM_198458 zinc finger protein 497 19q13.43 −2.3 nulliparous gene body SLC5A1 NM_000343 solute carrier family 5 (sodium/glucose cotransporter), member 1 22q12.3 −6.2 nulliparous gene body ODZ4 NM_001098816 odz, odd Oz/ten-m homolog 4 (Drosophila) 11q13 −3.6 nulliparous gene body SMOC2 NM_022138 SPARC related modular calcium binding 2 6q27 −3.3 nulliparous gene body LRRC37B2 NR_015341 leucine rich repeat containing 37, member B2 17q11.2 −3.9 nulliparous gene body SPTBN4 NM_020971 spectrin, beta, non-erythrocytic 4 19q13.13 −2.2 nulliparous gene body SPTBN4 NM_020971 spectrin, beta, non-erythrocytic 4 19q13.13 −3.2 nulliparous gene body FAM83G NM_001039999 family with sequence similarity 83, member G 17p11.2 −3.8 nulliparous gene body FAM83A NM_207006 family with sequence similarity 83, member A 8q24.13 −3.7 nulliparous gene body HIST1H2AC NM_003512 histone cluster 1, H2ac 6p22.1 −8.2 nulliparous gene body ZNF721 NM_133474 zinc finger protein 721 4p16.3 −4.6 nulliparous gene body PNLIPRP2 NM_005396 pancreatic lipase-related protein 2 10q26.12 −3.8 nulliparous gene body SUGT1P NR_003667 suppressor of G2 allele of SKP1 pseudogene (S. cerevisiae) 9p12 −2.1 nulliparous gene body RAB31 NM_006868 RAB31, member RAS oncogene family 18p11.3 −2.3 nulliparous gene body TOB2 NM_016272 transducer of ERBB2, 2 22q13.2 −4.1 nulliparous gene body NETO1 NM_153181 neuropilin (NRP) and tolloid (TLL)-like 1 18q22.2 −3.2 nulliparous gene body SVEP1 NM_153366 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 9q31-q32 −7.5 nulliparous gene body RB1 NM_000321 retinoblastoma 1 13q14.2 −2.4 nulliparous gene body FAM155A NM_001080396 family with sequence similarity 155, member A 13q33.3 −2.8 nulliparous gene body RAI1 NM_030665 retinoic acid induced 1 17p11.2 −2.5 nulliparous gene body RAI1 NM_030665 retinoic acid induced 1 17p11.2 −2.4 nulliparous gene body PDZD4 NM_032512 PDZ domain containing 4 Xq28 −4.5 nulliparous gene body SLIT3 NM_003062 slit homolog 3 (Drosophila) 5q35 −8.9 nulliparous gene body GBE1 NM_000158 glucan (1,4-alpha-), branching enzyme 1 3 −4.7 nulliparous gene body SULF1 NM_015170 sulfatase 1 8q13.1 −4.1 nulliparous gene body CABLES1 NR_023359 Cdk5 and Abl enzyme substrate 1 18q11.2 −3.7 nulliparous gene body PACSIN1 NM_020804 protein kinase C and casein kinase substrate in neurons 1 6p21.3 −3 nulliparous gene body DGKG NM_001080744 diacylglycerol kinase, gamma 90 kDa 3q27-q28 −2.3 nulliparous gene body YWHAE NM_006761 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 17p13 −2.3 nulliparous gene body C13orf33 NM_032849 chromosome 13 open reading frame 33 13q12.3 −3.6 nulliparous gene body PRDM2 NM_015866 PR domain containing 2, with ZNF domain 1p36 −9.1 nulliparous gene body ESRRB NM_004452 estrogen-related receptor beta 14q24.3 −2.7 nulliparous gene body ESRRB NM_004452 estrogen-related receptor beta 14q24.3 4.3 nulliparous gene body TPO NM_175722 thyroid peroxidase 2p25 −5.1 nulliparous gene body DAB2IP NM_032552 DAB2 interacting protein 9q33.1-q33.3 −3.9 nulliparous gene body CHRM5 NM_012125 cholinergic receptor, muscarinic 5 15q26 −3.8 nulliparous gene body NLGN4X NM_020742 neuroliqin 4, X-linked Xp22.33 −7.6 nulliparous gene body TANC1 NM_033394 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 2q24.2 −7.3 nulliparous gene body CHRM2 NM_000739 cholinergic receptor, muscarinic 2 7q35-q36 −6 nulliparous gene body LOC732275 NR_024406 NA NA −5.8 nulliparous gene body PIP5K1C NM_012398 phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 19p13.3 −3.3 nulliparous gene body LRRC55 NM_001005210 leucine rich repeat containing 55 11q12.1 −3 nulliparous gene body LOC389332 NR_024418 NA NA −2.1 nulliparous gene body USP18 NM_017414 ubiquitin specific peptidase 18 22q11.2 −4.1 nulliparous gene body SHANK3 NM_001080420 SH3 and multiple ankyrin repeat domains 3 22q13.3 −3.6 nulliparous gene body HM13 NM_178582 histocompatibility (minor) 13 20q11.21 −3.2 nulliparous gene body CTNNA2 NM_004389 catenin (cadherin-associated protein), alpha 2 2p12-pi1.1 −4.8 nulliparous gene body CTNNA3 NM_001127384 catenin (cadherin-associated protein), alpha 3 10q21 −11.8 nulliparous gene body CACNG3 NM_006539 calcium channel, voltage-dependent, gamma subunit 3 16p12.1 −2.2 nulliparous gene body PACRG NM_152410 PARK2 co-regulated 6q26 −4.7 nulliparous gene body RNU11 NR_004407 RNA, U11 small nuclear 1p35 −2.2 nulliparous gene body MXI1 NM_130439 MAX interactor 1 10q24-q25 −2.5 nulliparous gene body ALCAM NM_001627 activated leukocyte cell adhesion molecule 3q13.1 −4.7 nulliparous gene body CXorf41 NM_173494 chromosome X open reading frame 41 Xq22.3 −2.8 nulliparous gene body C3orf21 NM_152531 chromosome 3 open reading frame 21 3q29 −2.6 nulliparous gene body ANK2 NM_001127493 ankyrin 2, neuronal 4q25-q27 −5 nulliparous gene body PTPRB NM_001109754 protein tyrosine phosphatase, receptor type, B 12q15-q21 −2.2 nulliparous gene body FUT1 NM_000148 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 19q13.1-qter −5.5 nulliparous gene body ALPI NM_001631 alkaline phosphatase, intestinal 2q37.1 −3.2 nulliparous gene body PPP1R13L NM_006663 protein phosphatase 1, regulatory (inhibitor) subunit 13 like 19q13.32 −8.5 nulliparous gene body SLC2A9 NM_020041 solute carrier family 2 (facilitated glucose transporter), member 9 4p16.1 −9.5 nulliparous gene body LIMCH1 NM_001112718 LIM and calponin homology domains 1 4p13 −2.5 nulliparous gene body HEPACAM NM_152722 hepatocyte cell adhesion molecule 11q24.2 −3 nulliparous gene body LOC100188947 NR_024467 NA NA −3.2 nulliparous gene body LIN7B NM_022165 lin-7 homolog B (C. elegans) 19q13.3 −2.8 nulliparous gene body ESPN NM_031475 espin 1p36.31 −11.2 nulliparous gene body SFTPC NM_003018 surfactant protein C 8p21 −6.2 nulliparous gene body ISL1 NM_002202 ISL LIM homeobox 1 5q11.2 −8.9 nulliparous gene body GSC NM_173849 goosecoid homeobox 14q32.13 −2.4 nulliparous gene body TNRC6B NM_015088 trinucleotide repeat containing 6B 22q13 −2.9 nulliparous gene body A2BP1 NM_018723 NA NA −10.5 nulliparous gene body MRC2 NM_006039 mannose receptor, C type 2 17q23 −2.3 nulliparous gene body LHX4 NM_033343 LIM homeobox 4 1q25.3 −6.6 nulliparous gene body FAM110A NM_001042353 family with sequence similarity 110, member A 20p13 −2.3 nulliparous gene body FLII NM_002018 flightless I homolog (Drosophila) 17p11.2 −2.1 nulliparous gene body IRX3 NM_024336 iroquois homeobox 3 16q12.2 −2.9 nulliparous gene body KCNAB1 NM_172160 potassium voltage-gated channel, shaker-related subfamily, beta member 1 3q26.1 −7.7 nulliparous gene body AHRR NM_020731 aryl-hydrocarbon receptor repressor 5p15.33 −2.4 nulliparous gene body OCA2 NM_000275 oculocutaneous albinism II 15q11.2-qi2 −6.8 nulliparous gene body SOCS2 NM_003877 suppressor of cytokine signaling 2 12q −2.8 nulliparous gene body CNN2 NM_004368 calponin 2 19p13.3 −2.5 nulliparous gene body PLEKHA4 NM_020904 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 19q13.33 −9.2 nulliparous gene body RUNX1 NM_001754 runt-related transcription factor 1 21q22.3 −2.5 nulliparous gene body ZNF274 NM_016324 zinc finger protein 274 19q13.43 −6.3 nulliparous gene body MMP15 NM_002428 matrix metallopeptidase 15 (membrane-inserted) 16q13 −15.5 nulliparous gene body PDXK NM_003681 pyridoxal (pyndoxine, vitamin B6) kinase 21q22.3 −4.8 nulliparous gene body ELAVL2 NM_004432 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) 9p21 −3.4 nulliparous gene body HLA-G NM_002127 major histocompatibility complex, class I, G 6p21.3 −3.9 nulliparous gene body TBR1 NM_006593 T-box, brain, 1 2q24.2 −5.7 nulliparous gene body SLC25A37 NM_016612 solute carrier family 25, member 37 8p21.2 −11.3 nulliparous gene body MDGA1 NM_153487 MAM domain containing glycosylphosphatidylinositol anchor 1 6p21 −3.5 nulliparous gene body MAML3 NM_018717 mastermind-like 3 (Drosophila) 4q28 −7.7 nulliparous gene body TNRC18 NM_001080495 trinucleotide repeat containing 18 7p22.1 −14 nulliparous gene body PCDHB6 NM_018939 protocadherin beta 6 5q31 −2.4 nulliparous gene body NINJ2 NM_016533 ninjurin 2 12p13 −4.1 nulliparous gene body FLJ10490 NM_018111 NA NA −2.8 nulliparous gene body HOXB4 NM_024015 homeobox B4 17q21.32 −7.9 nulliparous gene body LRRC37B2 NR_015341 leucine rich repeat containing 37, member B2 17q11.2 −5.2 nulliparous gene body HIST2H3C NM_021059 histone cluster 2, H3c 1q21.2 −3.1 nulliparous gene body HIST2H3A NM_001005464 histone cluster 2, H3a 1q21.2 −3.1 nulliparous gene body COX7A1 NM_001864 cytochrome c oxidase subunit Vila polypeptide 1 (muscle) 19q13.1 −13.8 nulliparous gene body EPS8L2 NM_022772 EPS8-like 2 11p15.5 −2.3 nulliparous gene body GDI1 NM_001493 GDP dissociation inhibitor 1 Xq28 −3.2 nulliparous gene body C10orf140 NM_207371 chromosome 10 open reading frame 140 10p12.31 −2.4 nulliparous gene body UBE2K NM_005339 ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) 4p14 −6.4 nulliparous gene body FLJ36208 NM_176677 NA NA −6 nulliparous gene body ASFMR1 NR_024499 NA NA −2.7 nulliparous gene body SORT1 NM_002959 sortilin 1 1p13.3 −3.1 nulliparous gene body PRDM8 NM_020226 PR domain containing 8 4q21 −2.4 nulliparous gene body CTNND2 NM_001332 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 5p15.2 −4.8 nulliparous gene body ADCYAP1 NM_001099733 adenylate cydase activating polypeptide 1 (pituitary) 18p11 −2.3 nulliparous gene body GPRC5C NM_022036 G protein-coupled receptor, family C, group 5, member C 17q25 −33.1 nulliparous gene body CCDC106 NM_013301 coiled-coil domain containing 106 19q13.42 −5.1 nulliparous gene body ALCAM NM_001627 activated leukocyte cell adhesion molecule 3q13.1 −3.6 nulliparous gene body UNC5CL NM_173561 unc-5 homolog C (C. elegans)-like 6p21.1 −3 nulliparous gene body PCDHB10 NM_018930 protocadherin beta 10 5q31 −5.5 nulliparous gene body CITED1 NM_004143 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 Xq13.1 −2.1 nulliparous gene body HIST2H2AA3 NM_003516 histone cluster 2, H2aa3 1q21.2 −3.1 nulliparous gene body HIST2H2AA4 NM_001040874 histone cluster 2, H2aa4 1q21.2 −3.1 nulliparous gene body FLJ34048 NR_015448 NA NA −3.4 nulliparous gene body LAMP2 NM_002294 lysosomal-associated membrane protein 2 Xq24-q25 −2.5 nulliparous gene body SND1 NM_014390 staphylococcal nuclease and tudor domain containing 1 7q31.3 −3.9 nulliparous gene body FREQ NM_014286 frequenin homolog (Drosophila) 9q34.11 −2.9 nulliparous gene body FRMD4A NM_018027 FERM domain containing 4A 10p14 −2.7 nulliparous gene body ALOX12B NM_001139 arachidonate 12-lipoxygenase, 12R 17p13.1 −2.8 nulliparous gene body ALOX12B NM_001139 arachidonate 12-lipoxygenase, 12R 17p13.1 2.4 nulliparous gene body LMO3 NM_001001395 LIM domain only 3 (rhombotin-like 12p13 −4.9 nulliparous gene body MYO16 NM_015011 myosin XVI 13q33.3 −5.6 nulliparous gene body MYO16 NM_015011 myosin XVI 13q33.3 2.6 nulliparous gene body PTH1R NM_000316 parathyroid hormone 1 receptor 3p22-P21.1 −4.9 nulliparous gene body PTK7 NM_002821 PTK7 protein tyrosine kinase 7 6p21.1-p12.2 −11.6 nulliparous gene body JUNB NM_002229 jun B proto-oncogene 19p13.13 −7.8 nulliparous gene body BIRC2 NM_001166 baculoviral IAP repeat-containing 2 11q22 −9.6 nulliparous gene body ZNF497 NM_198458 zinc finger protein 497 19q13.43 −6.9 nulliparous gene body SLC5A1 NM_000343 solute carrier family 5 (sodium/glucose cotransporter), member 1 22q12.3 −10.1 nulliparous gene body SMOC2 NM_022138 SPARC related modular calcium binding 2 6q27 −3.3 nulliparous gene body HIST1H2AC NM_003512 histone cluster 1, H2ac 6p22.1 −3.6 nulliparous gene body PRICKLE1 NM_153026 prickle homolog 1 (Drosophila) 12p11-q12 −4.3 nulliparous gene body RNU11 NR_004407 RNA, U11 small nuclear 1p35 −3 nulliparous gene body LYPD1 NM_001077427 LY6/PLAUR domain containing 1 2q21.2 −3.4 nulliparous gene body RTBDN NM_031429 retbindin 19p13 −4.1 nulliparous gene body C9orf66 NM_152569 chromosome 9 open reading frame 66 9p24.3 −3.2 nulliparous gene body LOC100130987 NR_024469 NA NA −3.2 nulliparous gene body YWHAE NM_006761 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 17p13 −3.5 nulliparous gene body HEATR1 NM_018072 HEAT repeat containing 1 1q43 −2.8 nulliparous gene body INTS9 NM_018250 integrator complex subunit 9 8p21.1 −14.7 nulliparous gene body EBF1 NM_024007 early B-cell factor 1 5q34 −10.7 nulliparous gene body TLX2 NM_016170 T-cell leukemia homeobox 2 2p13.1 −6.4 nulliparous gene body TSGA13 NM_052933 testis specific, 13 7q32 −2.4 nulliparous gene body BCL9 NM_004326 B-cell CLL/lymphoma 9 1q21 −3.1 nulliparous gene body FOLR2 NM_000803 folate receptor 2 (fetal) 11q13.3-q14.1 −3.6 nulliparous gene body RECQL5 NM_004259 RecQ protein-like 5 17q25 2.1 parous gene body VAV2 NM_003371 vav 2 guanine nucleotide exchange factor 9q34.1 4.2 parous gene body TNFAIP8L3 NM_207381 tumor necrosis factor, alpha-induced protein 8-like 3 15q21.2 2.1 parous gene body C1orf106 NM_018265 chromosome 1 open reading frame 106 1q32.1 6.1 parous gene body ONECUT2 NM_004852 one cut homeobox 2 18q21.31 3.8 parous gene body DIP2C NM_014974 DIP2 disco-interacting protein 2 homolog C (Drosophila) 10p 15.3 2.7 parous gene body ZFHX3 NM_006885 zinc finger homeobox 3 16q22.3 3.8 parous gene body BCL11B NM_022898 B-cell CLL/lymphoma 11B (zinc finger protein) 14q32 3.7 parous gene body TNFRSF14 NM_003820 tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) 1p36.32 4.4 parous gene body ANKRD13B NM_152345 ankyrin repeat domain 13B 17q11.2 2.2 parous gene body B3GAT2 NM_080742 beta-1.3-glucuronyltransferase 2 (qlucuronosyltransferase S) 6q12 2.7 parous gene body BMP8A NM_181809 bone morphogenetic protein 8a 1p35-p32 2.8 parous gene body GAPVD1 NM_015635 GTPase activating protein and VPS9 domains 1 9q34.11 5 parous gene body RARG NM_001042728 retinoic acid receptor, gamma 12q13 2.2 parous gene body KIFC2 NM_145754 kinesin family member C2 8q24.3 3.6 parous gene body THRA NM_199334 thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) 17q21.1 2.7 parous gene body GPR124 NM_032777 G protein-coupled receptor 124 8p11.22 2.2 parous gene body DLGAP4 N M 014902 discs, large (Drosophila) homolog-associated protein 4 20 2.6 parous gene body TTLL12 NM_015140 tubulin tyrosine ligase-like family, member 12 22q13.31 4.9 parous gene body ALOX12B NM_001139 arachidonate 12-lipoxygenase, 12R type 17p13.1 −2.8 parous gene body ALOX12B NM_001139 arachidonate 12-lipoxygenase, 12R type 17p13.1 2.4 parous gene body ARHGEF10 NM_014629 Rho guanine nucleotide exchange factor (GEF) 10 8p23 2.7 parous gene body PHACTR1 NM_030948 phosphatase and actin regulator 1 6p23 2.2 parous gene body CASZ1 NM_001079843 castor zinc finger 1 1p36.22 21.3 parous gene body BMP8B NM_001720 bone morphogenetic protein 8b 1 p35-p32 2.8 parous gene body BRUNOL4 NM_020180 bruno-like 4, RNA binding protein (Drosophila) 18q12 3.9 parous gene body ACAP1 NM_014716 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 17p13.1 28.3 parous gene body FLJ45983 NR_024255 NA NA 2.9 parous gene body LOC643008 NR_024379 NA NA 2.1 parous gene body KIF26B NM_018012 kinesin family member 26B 1q44 2.4 parous gene body CHRNA3 NM_000743 cholinergic receptor, nicotinic, alpha 3 15q24 24.3 parous gene body FMN2 NM_020066 formin 2 1q43 21.9 parous gene body RAB40C NM_021168 RAB40C, member RAS oncogene family 16p13.3 5.2 parous gene body SLC25A42 NM_178526 solute carrier family 25, member 42 19p13.11 2.6 parous gene body MTHFSD NM_022764 methenyltetrahydrofolate synthetase domain containing 16q24.1 16.3 parous gene body EXOC3L NM_178516 exocyst complex component 3-like 16q22.1 6.3 parous gene body ASTN2 NM_198186 astrotactm 2 9q33 2.2 parous gene body ANKFY1 NM_016376 ankyrin repeat and FYVE domain containing 1 17p13.3 4.4 parous gene body LRRN4 NM_152611 leucine rich repeat neuronal 4 20p12.3 2.8 parous gene body ERF NM_006494 Ets2 repressor factor 19q13 4.1 parous gene body ATPGD1 NM_020811 ATP-grasp domain containing 1 11q13.1 2.5 parous gene body FLJ37453 NR_024279 NA NA 3.4 parous gene body MYO16 NM_015011 myosin XVI 13q33.3 −5.6 parous gene body MYO16 NM_015011 myosin XVI 13q33.3 2.6 parous gene body HES7 NM_032580 hairy and enhancer of split 7 (Drosophila) 17p13.1 55.5 nulliparous promoter DUOXA1 NM_144565 dual oxidase maturation factor 1 15q21.1 −4.5 nulliparous promoter HIST1H4G NM_003547 histone cluster 1, H4g 6p22.1 −2.5 nulliparous promoter C17orf76 NM_207387 chromosome 17 open reading frame 76 17p11.2 −2.3 nulliparous promoter PARS2 NM_152268 prolyt-tRNA synthetase 2, mitochondrial (putative) 1p32.2 −4.6 nulliparous promoter KIAA1012 NM_014939 KIAA1012 18q12.1 −2.9 nulliparous promoter OCA2 NM_000275 oculocutaneous albinism II 15q11.2-qi2 −6.8 nulliparous promoter HNRPLL NM_138394 heterogeneous nuclear ribonucleoprotein L-like 2p22 −5.7 nulliparous promoter PCDHB6 NM_018939 protocadherin beta 6 5q31 −2.4 nulliparous promoter N4BP2L1 NM_001079691 NEDD4 binding protein 2-like 1 13q13.1 −3.1 nulliparous promoter GSC NM_173849 goosecoid homeobox 14q32.13 −2.4 nulliparous promoter OAT NM_000274 ornithine aminotransferase (gyrate atrophy) 10q26 −2.6 nulliparous promoter POLS NM_006999 polymerase (DNA directed) sigma 5p15 −4.7 nulliparous promoter SEMA4C NM_017789 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 2q11.2 −3.6 nulliparous promoter SEMA4F NM_004263 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 2p13.1 −3.8 nulliparous promoter ACTG1 NM_001614 actin, gamma 1 17q25 −5.2 nulliparous promoter MRC2 NM_006039 mannose receptor, C type 2 17q23 −2.3 nulliparous promoter KIAA0564 NM_015058 KIAA0564 13q14.11 −4.1 nulliparous promoter DLG5 NM_004747 discs, large homolog 5 (Drosophila) 10q23 −12 nulliparous promoter C6orf120 NM_001029863 chromosome 6 open reading frame 120 6q27 −5.8 nulliparous promoter MBIP NM_016586 MAP3K12 binding inhibitory protein 1 14q13.2 −122.1 nulliparous promoter SAMD11 NM_152486 sterile alpha motif domain contaming 11 1p36.33 −3.5 nulliparous promoter FMNL3 NM_198900 formin-like 3 12q13.12 −4.4 nulliparous promoter BCLAF1 NM_001077440 BCL2-associated transcnption factor 1 6q22-q23 −5.8 nulliparous promoter STAP2 NM_017720 signal transducing adaptor family member 2 19p13.3 −3.3 nulliparous promoter N6AMT2 NM_174928 N-6 adenine-specific DNA methyltransferase 2 (putative) 13q12.11 −2.3 nulliparous promoter ZNF574 NM_022752 zinc finger protein 574 19 −4.7 nulliparous promoter NDUFA11 NM_175614 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7 kDa 19p13.3 −2.5 nulliparous promoter FOXF2 NM_001452 forkhead box F2 6p25.3 −5.6 nulliparous promoter MTMR7 NM_004686 myotubularin related protein 7 8p22 −3 nulliparous promoter MBNL1 NM_021038 muscleblind-like (Drosophila) 3q25 −6 nulliparous promoter HEBP2 NM_014320 heme binding protein 2 6q24 −2.6 nulliparous promoter C14orf151 NM_032714 NA NA −3.3 nulliparous promoter ONECUT1 NM_004498 one cut homeobox 1 15q21.3 −5.3 nulliparous promoter IRX3 NM_024336 iroquots homeobox 3 16q12.2 −2.9 nulliparous promoter ZMPSTE24 NM_005857 zinc metallopeptidase (STE24 homolog, S. cerevisiae) 1p34 −4.5 nulliparous promoter BAI1 NM_001702 brain-specific angiogenests inhibitor 1 8q24 −3.8 nulliparous promoter WRB NM_004627 tryptophan rich basic protein 21q22.3 −2.5 nulliparous promoter FAM19A3 NM_001004440 family with sequence similarity 19 (chemokine (C-C motif)-like), member A3 1p13.2 −17.6 nulliparous promoter PEX26 NM_017929 peroxisomal biogenesis factor 26 22q11.21 −7.8 nulliparous promoter PLD5 NM_152666 phospholipase D family, member 5 1q43 −11.6 nulliparous promoter LRRC4 NM_022143 leucine rich repeat containing 4 7q31 −3.9 nulliparous promoter SP1 NM_138473 Sp1 transcnption factor 12q13.1 −6.8 nulliparous promoter TSC22D3 NM_001015881 TSC22 domain family, member 3 Xq22.3 −2.1 nulliparous promoter SP3 NM_001017371 Sp3 transcnption factor 2q31 −3.3 nulliparous promoter SP4 NM_003112 Sp4 transcnption factor 7p15 −2.2 nulliparous promoter ZNF687 NM_020832 zinc finger protein 687 1q21.2 −34 nulliparous promoter OSTF1 NM_012383 osteoclast stimulating factor 1 9q13-q21.2 −3 nulliparous promoter NKRF NM_017544 NFKB repressing factor Xq24 −2.2 nulliparous promoter STK3 NM_006281 senne/threonine kinase 3 (STE20 homolog, yeast) 8q22.2 −5.9 nulliparous promoter PIN4 NM_006223 protein (peptidyiprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) Xq13.1 −2.2 nulliparous promoter RAE1 NM_003610 RAE1 RNA export 1 homolog (S. pombe) 20 −2.5 nulliparous promoter ARRDC3 NM_020801 arrestm domain containing 3 5q14.3 −4.8 nulliparous promoter TMEM184B NM_012264 transmembrane protein 184B 22q12 −6.4 nulliparous promoter ABHD6 NM_020676 abhydrolase domain containing 6 3p21.2 −3.6 nulliparous promoter CXCL16 NM_022059 chemokine (C-X-C motif) ligand 16 17p13 −2.2 nulliparous promoter SYNCRIP NM_006372 synaptotagmin binding, cytoplasmic RNA interacting protein 6q14-q15 −2.4 nulliparous promoter SYNCRIP NM_006372 synaptotagmin binding, cytoplasmic RNA interacting protein 6q14-q15 2.5 nulliparous promoter ADCYAP1 NM_001099733 adenylate cydase activating polypeptide 1 (pituitary) 18p11 −2.3 nulliparous promoter C19orf50 NM_024069 chromosome 19 open reading frame 50 19p13.11 −4.9 nulliparous promoter TRIOBP NM_138632 TRIO and F-adin binding protein 22q13.1 −2.5 nulliparous promoter BMP1 NM_006128 bone morphogenetic protein 1 8p21 −6.2 nulliparous promoter SLC2A8 NM_014580 solute carrier family 2 (facilitated glucose transporter), member 8 9q33.3 −3.2 nulliparous promoter C1orf31 NM_001012985 chromosome 1 open reading frame 31 1q42.2 −2.8 nulliparous promoter SLC2A4 NM_001042 solute carrier family 2 (facilitated glucose transporter), member 4 17p13 −15.7 nulliparous promoter PPFIA3 NM_003660 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 19 −2.8 nulliparous promoter ZBTB34 NM_001099270 zinc finger and BTB domain containing 34 9q33.3 −3.3 nulliparous promoter TTC14 NM_133462 tetratricopeptide repeat domain 14 3q27.2 −2.8 nulliparous promoter C1orf203 NR_024126 chromosome 1 open reading frame 203 1 p13.1 −3.1 nulliparous promoter RHBDD3 NM_012265 rhomboid domain containing 3 22q12.2 −5.3 nulliparous promoter GFRA3 NM_001496 GDNF family receptor alpha 3 5q31.1-q31.3 −2.9 nulliparous promoter PRR15 NM_175887 prolme rich 15 7p15.1 −2.6 nulliparous promoter YIPF1 NM_018982 Yip1 domain family, member 1 1p33-p32.1 −2.1 nulliparous promoter MTIF3 NM_152912 mitochondrial translational initiation factor 3 13q12.2 −8.6 nulliparous promoter ZNF37A NM_003421 zinc finger protein 37A 10p11.2 −2.5 nulliparous promoter CEP78 NM_032171 centrosomal protein 78 kDa 9q21.2 −2.6 nulliparous promoter EPHB2 NM_004442 EPH receptor B2 1p36.1-P35 −2.2 nulliparous promoter DMRT2 NM_001130865 doublesex and mab-3 related transcnption factor 2 9p24.3 −4.5 nulliparous promoter KCTD18 NM_152387 potassium channel tetramerisation domain containing 18 2q33.1 −10.6 nulliparous promoter OXSR1 NM_005109 oxidative-stress responsive 1 3p22.2 −18.5 nulliparous promoter HSD17B14 NM_016246 hydroxysteroid (17-beta) dehydroqenase 14 19q13.33 −9.2 nulliparous promoter NR3C2 NM_000901 nuclear receptor subfamily 3, group C, member 2 4q31 −4 nulliparous promoter ADORA1 NM_000674 adenosine A1 receptor 1q32.1 −4 nulliparous promoter CSTF3 NM_001033506 cleavage stimulation factor, 3″pre-RNA, subunit 3, 77 kDa 11 pi 3 −2.2 nulliparous promoter NUAK2 NM_030952 NUAK family, SNF1-like kinase, 2 1q32.1 −3.6 nulliparous promoter NFKBIA NM_020529 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 14q13 −3 nulliparous promoter HLA-G NM_002127 major histocompatibility complex, class 1, G 6p21.3 −3.9 nulliparous promoter TBR1 NM_006593 T-box, brain, 1 2q24.2 −5.7 nulliparous promoter DGKD NM_152879 diacylglycerol kinase, delta 130 kDa 2q37 −2.4 nulliparous promoter NAPRT1 NM_145201 nicotinate phosphonbosyltransferase domain containing 1 8q24.3 −3.1 nulliparous promoter C1QL4 NM_001008223 complement component 1, q subcomponent-like 4 12q13.12 −2.6 nulliparous promoter C9orf66 NM_152569 chromosome 9 open reading frame 66 9p24.3 −3.2 nulliparous promoter C9orf66 NM_152569 chromosome 9 open reading frame 66 9p24.3 3.2 nulliparous promoter CEP97 NM_024548 centrosomal protein 97 kDa 3q12.3 −24.9 nulliparous promoter PDHX NM_001135024 pyruvate dehydrogenase complex, component X 11 pi 3 −2.9 nulliparous promoter GUSB NM_000181 glucuronidase, beta 7q11.21 −5.6 nulliparous promoter GFER NM_005262 growth (actor, augmenter of liver regeneration 16p13.3-P13.12 −5.6 nulliparous promoter SUMF1 NM_182760 sulfatase modifying factor 1 3p26.1 −2.9 nulliparous promoter RWDD2A NM_033411 RWD domain containing 2A 6q15 −3.4 nulliparous promoter ATAD3A NM_018188 ATPase family, AAA domain containing 3A 1p36.33 −14 nulliparous promoter LOC284422 NM_001136503 NA NA −2.9 nulliparous promoter U2AF2 NM_007279 U2 small nuclear RNA auxiliary factor 2 19q13.43 −5.1 nulliparous promoter CLDND1 NM_001040200 daudin domain containing 1 3q12.1 −8.2 nulliparous promoter PPM1J NM_005167 protein phosphatase 1J (PP2C domain containing) 1 p13.1 −17.6 nulliparous promoter C17orf68 NM_025099 chromosome 17 open reading frame 68 17p13.1 −2.3 nulliparous promoter ABCA5 NM_172232 ATP-binding cassette, sub-family A (ABC1), member 5 17q21-q25 −7.5 nulliparous promoter DIO1 NM_001039715 deiodinase, iodothyronme, type I 1 p33-p32 −2.1 nulliparous promoter HIST2H2AA4 NM_001040874 histone cluster 2, H2aa4 1q21.2 −3.1 nulliparous promoter FNDC3A NM_001079673 fibronectm type III domain containing 3A 13q14.12 −6.5 nulliparous promoter GPR161 NM_153832 G protein-coupled receptor 161 1q23.3 −4.1 nulliparous promoter NPEPPS NM_006310 aminopeptidase puromycin sensitive 17q12-q21 −3.2 nulliparous promoter PLXDC2 NM_032812 plexin domain containing 2 10p12.33 −3 nulliparous promoter LZTS1 NM_021020 leucine zipper, putative tumor suppressor 1 8p22 −5.1 nulliparous promoter C16orf67 NR_024034 chromosome 16 open reading frame 67 16p11.2 −4.2 nulliparous promoter TCF4 NM_001083962 transcnption factor 4 18q21. −9.5 nulliparous promoter FU10490 NM_018111 NA NA −2.8 nulliparous promoter C1QL3 NM_001010908 complement component 1, q subcomponent-like 3 10p13 −3.2 nulliparous promoter FRAS1 NM_025074 Fraser syndrome 1 4q21 −2.9 nulliparous promoter XPOT NM_007235 exportin, tRNA (nuclear export receptor for tRNAs) 12q14.1 −3.1 nulliparous promoter HOXB3 NM_002146 homeobox B3 17q21.32 −7.9 nulliparous promoter SPATA18 NM_145263 spermatogenesis associated 18 homolog (rat) 4q11 −2.3 nulliparous promoter HOXB4 NM_024015 homeobox B4 17q21.32 −7.9 nulliparous promoter PGM3 NM_015599 phosphoglucomutase 3 6q14.1- −3.4 nulliparous promoter HERC3 NM_014606 hect domain and RLD 3 4q21 −4.4 nulliparous promoter HIST2H3C NM_021059 histone cluster 2, H3c 1q21.2 −3.1 nulliparous promoter HIST2H3A NM_001005464 histone cluster 2, H3a 1q21.2 −3.1 nulliparous promoter HIST1H2BC NM_003526 histone cluster 1, H2bc 6p22.1 −3.6 nulliparous promoter CHST1 NM_003654 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 11 pi 1.2 −3.9 nulliparous promoter COX7A1 NM_001864 cytochrome c oxidase subunit Vila polypeptide 1 (musde) 19q13.1 −13.8 nulliparous promoter LMO3 NM_001001395 LIM domain only 3 (rhombotin-like 2) 12p13 −4.9 nulliparous promoter HIST1H2BH NM_003524 histone cluster 1, H2bh 6p21.3 −2.5 nulliparous promoter GARS NM_002047 glycyl-tRNA synthetase 7p15 −5.3 nulliparous promoter TRIM41 NM_033549 tripartite motif-containing 41 5q35.3 −11.1 nulliparous promoter ZDHHC1 NM_013304 zinc finger, DHHC-type containing 1 16q22.1 −4.1 nulliparous promoter EPAS1 NM_001430 endothelial PAS domain protein 1 2p21-p16 −5.2 nulliparous promoter OLFML2A NM_182487 olfactomedin-like 2A 9q34.11 −10.7 nulliparous promoter SRXN1 NM_080725 sulfiredoxin 1 homolog (S. cerevisiae) 20p13 −3.1 nulliparous promoter FAM50A NM_004699 family with sequence similarity 50, member A Xq28 −3.2 nulliparous promoter PEX6 NM_000287 peroxisomal biogenesis factor 6 6p22-p11 −5 nulliparous promoter CYP881 NM_004391 cytochrome P450, family 8, subfamily B, polypeptide 1 3p22.1 −4.4 nulliparous promoter HLCS NM_000411 holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase) 21q22.1 −3.3 nulliparous promoter ADFP NM_001122 NA NA −5.1 nulliparous promoter INSM1 NM_002196 insulinoma-associated 1 20p11.2 −3 nulliparous promoter FBXO34 NM_152231 F-box protein 34 14q22.1 −22.7 nulliparous promoter HS6ST1 NM_004807 heparan sulfate 6-0-sulfotransferase 1 2q21 −3.6 nulliparous promoter MEF2D NM_005920 myocyte enhancer factor 2D 1q12-q23 −8.8 nulliparous promoter NSD1 NM_022455 nuclear receptor binding SET domain protein 1 5q35 −3.4 nulliparous promoter FLNB NM_001457 filamin B, beta 3p14.3 −2.6 nulliparous promoter SCN5A NM_198056 sodium channel, voltage-gated, tuna V/ alnha ciihnnil 3p21 −2.1 nulliparous promoter AGFG2 NM_006076 ArlGAP with FG repeats 2 7q22.1 −7.1 nulliparous promoter COX15 NM_004376 COX15 homolog, cytochrome c oxidase assembly protein (yeast) 10q24 −2.6 nulliparous promoter PPP2R5B NM_006244 protein phosphatase 2, regulatory subunit B\ beta isoform 11q12 −3.9 nulliparous promoter CYP26C1 NM_183374 cytochrome P450, family 26, subfamily C, polypeptide 1 10q23.33 −9.3 nulliparous promoter MGC33894 NM_152914 NA NA −2.8 nulliparous promoter PKM2 NM_182471 pyruvate kinase, muscle 15q22-qter −2.1 nulliparous promoter VMAC NM_001017921 vimentin-type intermediate filament associated coiled-coil protein 19p13.3 −2.5 nulliparous promoter APIP NM_015957 APAF1 interacting protein 11 pi 3 −2.9 nulliparous promoter CAPZB NM_004930 capping protein (actin filament) muscle Z-lme, beta 1p36.1 −4.4 nulliparous promoter C8orf55 NM_016647 chromosome 8 open reading frame 55 8q24.3 −4.7 nulliparous promoter NOXO1 NM_144603 NADPH oxidase organizer 1 16p13.3 −5.6 nulliparous promoter UFD1L NM_001035247 ubiquitin fusion degradation 1 like 22q11.2 −15.1 nulliparous promoter DHRS3 NM_004753 dehydrogenase/reductase (SDR family) member 3 1p36.1 −5 nulliparous promoter CYP20A1 NM_177538 cytochrome P450, family 20, subfamily A, polypeptide 1 2g33 −4.2 nulliparous promoter ZNF835 NM_001005850 zinc finger protein 835 19g13.43 −2.8 nulliparous promoter PPA2 NM_006903 pyrophosphatase (inorganic) 2 4g25 −3.9 nulliparous promoter REL NM_002908 v-rel reticuloendotheliosis viral oncogene homolog (avian) 2p13-p12 −9.7 nulliparous promoter FBXO7 NM_001033024 F-box protein 7 22q11.2-gter −7.1 nulliparous promoter SNTB2 NM_006750 syntrophin, beta 2 (dystrophin-associated protein A1, 59 kDa, basic component 2) 16g22.1 −2.2 nulliparous promoter GPKOW NM_015698 G patch domain and KOW motifs Xp11.23 −2.6 nulliparous promoter INF2 NM_022489 inverted formin, FH2 and WH2 domain containing 14g32.33 −3.3 nulliparous promoter GPRC5C NM_022036 G protein-coupled receptor, family C, group 5, member C 17g25 −33.1 nulliparous promoter FNIP1 NM_001008738 folliculin interacting protein 1 5g23.3 −5.2 nulliparous promoter FZD2 NM_001466 frizzled homolog 2 (Drosophila) 17g21.1 −2.5 nulliparous promoter SCRIB NM_182706 scribbled homolog (Drosophila) 8g24.3 −2.3 nulliparous promoter NR6A1 NM_033334 nuclear receptor subfamily 6, group A, member 1 9q33.3 −10.7 nulliparous promoter PELI3 NM_001098510 pellino homolog 3 (Drosophila) 11q13.2 −13.1 nulliparous promoter WDR27 NM_182552 WD repeat domain 27 6q27 −5.8 nulliparous promoter FLJ20433 NM_017820 NA NA −2.3 nulliparous promoter ALCAM NM_001627 activated leukocyte cell adhesion molecule 3q13.1 −3.6 nulliparous promoter CUTC NM_015960 cutC copper transporter homolog (E. coli) 10q24.31 −2.6 nulliparous promoter BMP2K NM_017593 BMP2 inducible kinase 4q21.21 −3.1 nulliparous promoter PIK3R2 NM_005027 phosphomositide-3-kinase, regulatory subunit 2 (beta) 19q13.2-q13.4 −3 nulliparous promoter PCDHB11 NM_018931 protocadherin beta 11 5q31 −5.5 nulliparous promoter PCDHB10 NM_018930 protocadherin beta 10 5q31 −5.5 nulliparous promoter PCDHB17 NR_001280 protocadherin beta 17 pseudogene 5q31 −2.4 nulliparous promoter PPP1R12C NM_017607 protein phosphatase 1, regulatory (inhibitor) subunit 12C 19q13.42 −2.1 nulliparous promoter DUSP5 NM_004419 dual specificity phosphatase 5 10q25 −2.3 nulliparous promoter DUSP4 NM_057158 dual specificity phosphatase 4 8p12-p11 −2.8 nulliparous promoter CITED1 NM_004143 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 Xq13.1 −2.1 nulliparous promoter HIST2H2AA3 NM_003516 histone cluster 2, H2aa3 1q21.2 −3.1 nulliparous promoter PENK NM_006211 proenkephalm 8q23-q24 −2.2 nulliparous promoter RAB14 NM_016322 RAB14, member RAS oncogene family 9q32-q34.11 −2.9 nulliparous promoter CLIC4 NM_013943 chloride intracellular channel 4 1p −3.1 nulliparous promoter CEP55 NM_018131 centrosomal protein 55 kDa 10q24.1 −3.2 nulliparous promoter KLHL21 NM_014851 kelch4ike21 (Drosophila) 1p36 −2.7 nulliparous promoter WBSCR16 NM_030798 Williams-Beuren syndrome chromosome region 16 7q11.23 −6.7 nulliparous promoter ASCL2 NM_005170 achaete-scute complex homolog 2 (Drosophila) 11p15.5 −2.1 nulliparous promoter PMP22 NM_153321 peripheral myelin protein 22 17p12 −5 nulliparous promoter DNAJC22 NM_024902 DnaJ (Hsp40) homolog, subfamily C, member 22 12q13.12 −2.6 nulliparous promoter BARX2 NM_003658 BARX homeobox 2 11q24.3 −2.9 nulliparous promoter IRX5 NM_005853 iroquois homeobox 5 16q12.2 −2.1 nulliparous promoter DCTN4 NM_001135644 dynactm 4 (p62) 5q31-q32 −2.5 nulliparous promoter ELMOD2 NM_153702 ELMO/CED-12 domain containing 2 4q31.1 −3.4 nulliparous promoter DTNB NM_021907 dystrobrevin, beta 2p23.2 −3.5 nulliparous promoter PRKAR1A NM_212471 protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 17q23-q24 −6.3 nulliparous promoter IGF2BP1 NM_006546 insulin-like growth factor 2 mRNA binding protein 1 17q21.32 −2.8 nulliparous promoter KCNB2 NM_004770 potassium voltage-gated channel, Shab-related subfamily, member 2 8q13.2 −10.7 nulliparous promoter DUOX1 NM_175940 dual oxidase 1 15q21 −4.5 nulliparous promoter HEY2 NM_012259 hairy/enhancer-of-split related with YRPW motif 2 6q −6.2 nulliparous promoter HNRNPUL1 NM_144732 heterogeneous nuclear ribonucleoprotein U-like 1 19q13.31 −5.7 nulliparous promoter C14orf94 NM_017815 NA NA −2.7 nulliparous promoter ZNF639 NM_016331 zinc finger protein 639 3q27.1 −2.1 nulliparous promoter KIF1B NM_183416 kinesin family member 1B 1 p36.22 −4.5 nulliparous promoter ZNF787 NM_001002836 zinc finger protein 787 19q13.42 −3.1 nulliparous promoter FAM20A NM_017565 family with sequence similarity 20, member A 17q24.3 −2.7 nulliparous promoter GRIK3 NM_000831 glutamate receptor, ionotropic, kainate 3 1p34-p33 −2.5 nulliparous promoter NAB2 NM_005967 NGFI-A binding protein 2 (EGR1 binding protein 2) 12q13.3 −2.2 nulliparous promoter ZFP36 NM_003407 zinc finger protein 36, C3H type, homoloq (mouse) 19q13.1 −2.2 nulliparous promoter NXT1 NM_013248 NTF2-like export factor 1 20p12-pi 1.2 −2.8 nulliparous promoter AATF NM_012138 apoptosis antagonizing transcription factor 17q12 −5.3 nulliparous promoter PFAS NM_012393 phosphor ibosytformylglycinamidine synthase 17p13.1 −2.3 nulliparous promoter NKX3-1 NM_006167 NK3 homeobox 1 8p21.2 −4.7 nulliparous promoter DEM1 NM_022774 defects in morphology 1 homolog (S. cerevisiae) 1p34.2 −3 nulliparous promoter MYL6B NM_002475 myosin, light chain 6B, alkali, smooth muscle and non-muscle 12q13.2 −3.1 nulliparous promoter MAD2L2 NM_006341 MAD2 mitotic arrest deficient-like 2 1p36 −2.8 nulliparous promoter RBM6 NM_005777 RNA binding motif protein 6 3p21.3 −4.8 nulliparous promoter SPHK1 NM_021972 sphingosine kinase 1 17q25.2 −4.2 nulliparous promoter BTRC NM_003939 beta-transdudn repeat containing 10q24.32 −5.9 nulliparous promoter RBM3 NM_006743 RNA binding motif (RNP1, RRM) protein 3 Xp11.2 −3.9 nulliparous promoter EPS8 NM_004447 epidermal growth factor receptor pathway substrate 8 12p12.3 −7.5 nulliparous promoter CD55 NM_001114752 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1q32 −2.4 nulliparous promoter A1BG NM_130786 alpha-1-B glycoprotein 19q −6.9 nulliparous promoter FLJ40125 NM_001080401 NA NA −5.3 nulliparous promoter JUNB NM_002229 jun B proto-oncogene 19p13.13 −7.8 nulliparous promoter SCP2 NM_001007098 sterol earner protein 2 1p32 −5.8 nulliparous promoter CPEB2 NM_182485 cytoplasmic polyadenytation element binding protein 2 4p15.33 −3 nulliparous promoter CBX8 NM_020649 chromobox homolog 8 (Pc class homolog, Drosophila) 17q25.3 −9.4 nulliparous promoter NOXA1 NM_006647 NAD PH oxidase activator 1 9 −2.3 nulliparous promoter PRSS3 NM_007343 protease, serine, 3 9p13 −2.1 nulliparous promoter ZMYND15 NM_001136046 zinc finger, MYND-type containing 15 17p13.3 −2.2 nulliparous promoter MAP7 NM_003980 microtubule-associated protein 7 6q23.2 −2.3 nulliparous promoter WDR82 NM_025222 WD repeat domain 82 3p21.2 −5.6 nulliparous promoter N4BP3 NM_015111 NA NA −4.2 nulliparous promoter ZNF813 NM_001004301 zinc finger protein 813 19q13.41 −2.7 nulliparous promoter DKK3 NM_001018057 dickkopf homolog 3 (Xenopus laevis) 11 p15.3 −2.4 nulliparous promoter B3GNT9 NM_033309 UDP-GlcNAc:betaGal beta-1.3-N-acetylglucosaminyltransferase 9 16q22.1 −6.7 nulliparous promoter UIMC1 NM_016290 ubiquitin interaction motif containing 1 5q35.2 −2.5 nulliparous promoter C1orf187 NM_198545 chromosome 1 open reading frame 187 1p36.22 −4.3 nulliparous promoter ZNF721 NM_133474 zincfinger protein 721 4p16.3 −18.9 nulliparous promoter MEF2C NM_002397 myocyte enhancer factor 2C 5q14 −2.2 nulliparous promoter PTPN21 NM_007039 protein tyrosine phosphatase, non-receptor type 21 14q31 −3.4 nulliparous promoter ERBB4 NM_001042599 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 2q33.3-q34 −2.1 nulliparous promoter INPPL1 NM_001567 inositol polyphosphate phosphatase-like 1 11q23 −3.6 nulliparous promoter LYPD1 NM_001077427 LY6.'PLAUR domain containing 1 2q21.2 −3.4 nulliparous promoter EWSR1 NM_005243 Ewing sarcoma breakpoint region 1 22q12.2 −5.3 nulliparous promoter ODC1 NM_002539 ornithine decarboxylase 1 2p25 −2.5 nulliparous promoter GLI3 NM_000168 GLI family zinc finger 3 7p13 −9.5 nulliparous promoter KIF5C NM_004522 kinesin family member 5C 2q23 −2.6 nulliparous promoter COPG2 NM_012133 coatomer protein complex, subunit gamma 2 7q32 −2.4 nulliparous promoter SGMS1 NM_147156 sphingomyelin synthase 1 10q11.2 −2.3 nulliparous promoter DNAJC10 NM_018981 DnaJ (Hsp40) homolog, subfamily C, member 10 2q32.1 −2.5 nulliparous promoter HOMER1 NM_004272 homer homolog 1 (Drosophila) 5q14.2 −2.7 nulliparous promoter SLC35E2 NM_182838 solute carrier family 35, member E2 1p36.32 −33.6 nulliparous promoter SEMA6A NM_020796 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 5q23 −2.3 nulliparous promoter VISA NM_020746 NA NA −7.6 nulliparous promoter CISD2 NM_001008388 CDGSH iron sulfur domain 2 4q24 −2.6 nulliparous promoter MFSD9 NM_032718 major facilitator supertamily domain containing 9 2q12.1 −2.5 nulliparous promoter MPND NM_032868 MPN domain containing 19p13.3 −3.3 nulliparous promoter CYR61 NM_001554 cysteine-rich, angiogenic inducer, 61 1p22.3 −2.4 nulliparous promoter HIST1H2AC NM_003512 histone cluster 1, H2ac 6p22.1 −3.6 nulliparous promoter PIGG NM_001127178 phosphatidylinositol glycan anchor biosynthesis, class G 4p16.3 −18.9 nulliparous promoter SUPT16H NM_007192 suppressor of Ty 16 homolog (S. cerevisiae) 14q11.1 −2.2 nulliparous promoter TLX2 NM_016170 T-cell leukemia homeobox 2 2p13.1 −6.4 nulliparous promoter CDC42EP1 NM_152243 CDC42 effector protein (Rho GTPase binding) 1 22q13.1 −60.5 nulliparous promoter GLRB NM_000824 glycine receptor, beta 4q31.3 −5.6 nulliparous promoter RTN2 NM_005619 reticulon 2 19q13.2-q13.3 −5.3 nulliparous promoter AP2S1 NM_021575 adaptor-related protein complex 2, sigma 1 subunit 19q13.2-q13.3 −19.7 nulliparous promoter PIGQ NM_148920 phosphatidylinositol glycan anchor biosynthesis, class G 16p13.3 −6 nulliparous promoter POU4F2 NM_004575 POU class 4 homeobox 2 4q31.22 −2.8 nulliparous promoter HIST1H3F NM_021018 histone cluster 1, H3f 6p22.1 −2.5 nulliparous promoter PIGU NM_080476 phosphatidylinositol glycan anchor biosynthesis, class U 20q11.22 −3.2 nulliparous promoter SLK NM_014720 STE20-like kinase (yeast) 10q25.1 −5.9 nulliparous promoter VASP NM_003370 vasodilator-stimulated phosphoprotein 19q13.2-q13.3 −2.5 nulliparous promoter ANKRD34B NM_001004441 ankyrin repeat domain 34B 5q14.1 −2.5 nulliparous promoter MICALL2 NM_182924 MICAL-like 2 7p22.3 −31.6 nulliparous promoter FEZF1 NM_001024613 FEZ family zinc finger 1 7q31.32 −6.2 nulliparous promoter SLC35F5 NM_025181 solute carrier family 35, member F5 2q14.1 −4.6 nulliparous promoter SLC25A22 NM_024698 solute carrier family 25 (mitochondrial carrier:glutamate), member 22 11 −2.9 nulliparous promoter RNU11 NR_004407 RNA, U11 small nuclear 1p35 −3 nulliparous promoter CLP1 NM_006831 CLP1, cleavage and polyadenylation factor 1 subunit, homolog (S. cerevisiae) 11q12 −3.3 nulliparous promoter LGALS8 NM_201544 lectin, galactoside-binding, soluble, 8 1q43 −3.1 nulliparous promoter AARS NM_001605 alanyHRNA synthetase 16q22 −7.5 nulliparous promoter DKK2 NM_014421 dickkopf homolog 2 (Xenopus laevis) 4q25 −7.8 nulliparous promoter AGAP2 NM_001122772 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 12q13.2 −3.1 nulliparous promoter ELA2 NM_001972 NA NA −2.1 nulliparous promoter LOC201229 NM_001076680 NA NA −7.1 nulliparous promoter CREB3L2 NM_194071 cAMP responsive element binding protein 3-like 2 7q34 −3 nulliparous promoter NEDD4L NM_015277 neural precursor cell expressed, developmentally down-regulated 4-like 18q21 −2.1 nulliparous promoter SFRS15 NM_020706 splicing factor, arginine/serine-nch 15 21q22.1 −4.6 nulliparous promoter RND3 NM_005168 Rho family GTPase 3 2q23.3 −2.2 nulliparous promoter PAX9 NM_006194 pared box 9 14q13.3 −2.7 nulliparous promoter ACTL6B NM_016188 actin-like 6B 7q22 −2.5 nulliparous promoter C9orf95 NM_017881 chromosome 9 open reading frame 95 9q21.31 −3 nulliparous promoter CNN2 NM_004368 calponin 2 19p13.3 −2.5 nulliparous promoter CDC45L NM_003504 CDC45 cell division cyde 45-like (S. cerevisiae) 22q11.21 −15.1 nulliparous promoter PICALM NM_001008660 phosphatidylinositol binding dathnn assembly protein 11q14 −2.8 nulliparous promoter C1orf94 NM_001134734 chromosome 1 open reading frame 94 1p34.3 −2.2 nulliparous promoter ASB13 NM_024701 ankyrin repeat and SOCS box-containing 13 10p15.1 2.6 parous promoter CRAMP1L NM_020825 Crm, cramped-like (Drosophila) 16p13.3 2.1 parous promoter HSPA8 NM_006597 heat shock 70 kDa protein 8 11q24.1 4.4 parous promoter CDO1 NM_001801 cysteine dioxygenase, type I 5q23.2 7.7 parous promoter UBAC1 NM_016172 UBA domain containing 1 9q34.3 5 parous promoter ATP2C2 NM_014861 ATPase, Ca++ transporting, type 2C, member 2 16q24.1 3.8 parous promoter PRPF4 NM_004697 PRP4 pre-mRNA processing factor 4 homoloq (yeast) 9q31-q33 2.2 parous promoter SLC30A3 NM_003459 solute carrier family 30 (zinc transporter), member 3 2p23.3 4.2 parous promoter SAMD14 NM_174920 sterile alpha motif domain containing 14 17q21.33 2.9 parous promoter C1orf174 NM_207356 chromosome 1 open reading frame 174 1p36.32 3 parous promoter DSC2 NM_024422 desmocollin 2 18q12.1 2.6 parous promoter NXPH3 NM_007225 neurexophilin 3 17q 2.3 parous promoter WHSC1L1 NM_023034 Wolf-Hirschhorn syndrome candidate 1-like 1 8p11.2 4.8 parous promoter DGCR6 NM_005675 DiGeorge syndrome cntical region qene 6 22q11.21 9.4 parous promoter GUK1 NM_000858 guanylate kinase 1 1q32-q41 3.1 parous promoter SYNCRIP NM_006372 synaptotagmin binding, cytoplasmic RNA interacting protein 6q14-q15 −2.4 parous promoter SYNCRIP NM_006372 synaptotagmin binding, cytoplasmic RNA interacting protein 6q14-q15 2.5 parous promoter IRX2 NM_001134222 iroquois homeobox 2 5p15.33 2.7 parous promoter BRP44 NM_015415 brain protein 44 1q24 5.3 parous promoter ALOXE3 NM_021628 arachidonate lipoxygenase 3 17p13.1 55.5 parous promoter KCTD11 NM_001002914 potassium channel tetramerisation domain containing 11 17p13.2 28.3 parous promoter SCAND1 NM_033630 SCAN domain containing 1 20q11.1-q11.23 4.4 parous promoter SHOX2 NM_003030 short stature homeobox 2 3q25.32 2.1 parous promoter C7orf46 NM_199136 chromosome 7 open reading (rame 46 7p15.3 4.4 parous promoter LIME1 NM_017806 Lck interacting transmembrane adaptor 1 20q13.3 2.2 parous promoter ZNF444 NM_018337 zinc finger protein 444 19q13.43 21.6 parous promoter FAM76B NM_144664 family with sequence similarity 76, member B 11q21 7.5 parous promoter ACCN2 NM_020039 amiloride-sensitive cation channel 2, neuronal 12q12 2.4 parous promoter KCTD14 NM_023930 potassium channel tetramerisation domain containing 14 11q13.4 13.3 parous promoter SYK NM_003177 spleen tyrosine kinase 9q22 4 parous promoter LOC100133 612 NR_024455 NA NA 3 parous promoter PKIG NM_007066 protein kinase (cAMP-dependent, catalytic) inhibitor gamma 20q13.12-q13.13 2.5 parous promoter SHROOM1 NM_133456 shroom family member 1 5q31.1 13.5 parous promoter FBXL7 NM_012304 F-box and leudne-rich repeat protein 7 5p15.1 2.4 parous promoter NPB NM_148896 neuropeptide B 17q25.3 5 parous promoter CCND1 NM_053056 cydin D1 11q13 2.1 parous promoter SNHG1 NR_003098 small nucleolar RNA host gene 1 (non-protein coding) 11q12.3 4.6 parous promoter FAM36A NM_198076 family with sequence similarity 36, member A 1q44 2.9 parous promoter GNA12 NM_007353 guanine nucleotide binding protein (G protein) alpha 12 7p22.3 3.1 parous promoter LOC653319 NM_001040715 NA NA 6.3 parous promoter LGR5 NM_003667 leucine-rich repeat-containing G protein-coupled receptor 5 12q22-q23 3.3 parous promoter ANKRD57 NM_023016 ankyrin repeat domain 57 2q13 2.9 parous promoter CDKN1C NM_000076 cydin-dependent kinase inhibitor 1C (p57, Kip2) 11p15.5 2.3 parous promoter GSTZ1 NM_001513 glutathione transferase zeta 1 14q24.3 2.7 parous promoter SLC7A5 NM_003486 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 16q24.3 2.9 parous promoter KAT2A NM_021078 K(lysine) acetyltransferase 2A 17q12-q21 2.8 parous promoter SERINC2 NM_178865 serine incorporator 2 1p35.1 2.1 parous promoter SNED1 NM_001080437 sushi, nidogen and EGF-like 2q37.3 2.1 parous promoter LPPR4 NM_014839 NA NA 2.7 parous promoter KREMEN2 NM_024507 kringle containing transmembrane protein 2 16p13.11 19.4 parous promoter CTXN1 NM_206833 cortexin 1 19 2.9 parous promoter GPRASP1 NM_014710 G protein-coupled receptor associated sorting protein 1 Xq22.1 5.1 parous promoter NT5M NM_020201 5″,3″-nucleotidase, mitochondrial 17p11.2 5.1 parous promoter USP48 NM_032236 ubiquitin specific peptidase 48 1p36.12 2.3 parous promoter YPEL2 NM_001005404 yippee-like 2 (Drosophila) 17q23 2.9 parous promoter SCD NM_005063 stearoyl-CoA desaturase (delta-9-desaturase) 10q23-q24 35.1 parous promoter PPM1L NM_139245 protein phosphatase 1 (formerly 2C)-like 3q26.1 2.2 parous promoter NCRNA00092 NR_024129 non-protein coding RNA 92 9q22.32 2.8 parous promoter LOC389634 NR_024420 NA NA 3.7 parous promoter IFT122 NM_018262 intraflagellar transport 122 homolog (Chlamydomonas) 3q21 4 parous promoter CCL25 NM_005624 chemokine (C-C motif) ligand 25 19p13.2 3.8 parous promoter EPM2A NM_005670 epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 6q24 2.6 parous promoter SH2D4A NM_022071 SH2 domain containing 4A 8p21 6.3 parous promoter EFS NM_032459 embryonal Fyn-assoaated substrate 14q11.2- 3.3 parous promoter PHRF1 NM_020901 PHD and ring finger domains 1 11p15.5 2.9 parous promoter DDT NM_001084392 D-dopachrome tautomerase 22q11.23 3.9 parous promoter CUX1 NM_181552 cut-like homeobox 1 7q22.1 2.4 parous promoter SFPQ NM_005066 splicing factor proline/glutamine-rich (polypyTimidine tract binding protein associated) 1p34.3 2.2 parous promoter LOC85389 NR_001453 NA NA 4.4 parous promoter CNTFR NM_001842 aliary neurotrophic factor receptor 9p13 2.5 parous promoter TMEM95 NM_198154 transmembrane protein 95 17p13.1 28.3 parous promoter HIST1H2BI NM_003525 histone cluster 1, H2bi 6p22.1 2.2 parous promoter SEMA5B NM_001031702 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and 3q21.1 11.2 short cytoplasmic domain, (semaphorin) 5B parous promoter VASH1 NM_014909 vasohibin 1 14q24.3 2.5 parous promoter SLC3A2 NM_001012663 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 11q12-q22 4.6 parous promoter CDC26 NM_139286 cell division cyde 26 homolog (S. cerevisiae) 9q32 2.2 parous promoter SPOCK1 NM_004598 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 5q31.2 2.3 parous promoter SLC18A3 NM_003055 solute carrier family 18 (vesicular acetylcholine), member 3 10q11.2 4.7 parous promoter ZNF114 NM_153608 zinc finger protein 114 19q13.32 2.4 parous promoter POMT2 NM_013382 protein-O-mannosyltransferase 2 14q24 2.7 parous promoter LCORL NM_153686 ligand dependent nudear receptor corepressor-like 4p15.32 3.8 parous promoter HES7 NM_032580 hairy and enhancer of split 7 (Drosophila) 17p13.1 55.5 parous promoter GIGYF1 NM_022574 GRB10 interacting GYF protein 1 7q22 11.1 parous promoter CCDC48 NM_024768 coiled-coil domain containing 48 3q21.3 2.1 parous promoter HOXA13 NM_000522 homeobox A13 7p15.2 3.3 parous promoter PAPD5 NM_001040284 PAP associated domain containing 5 16q12.1 3.6 parous promoter LETM2 NM_144652 leucine zipper-EF-hand containing transmembrane protein 2 8p12 4.8 parous promoter LOC85391 NR_003125 NA NA 4.4 parous promoter SMPD4 NM_017751 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) 2q21.1 6.2 parous promoter FBXO2 NM_012168 F-box protein 2 1p36.21 4.6 parous promoter ADAMTS15 NM_139055 ADAM metallopeptidase with thrombospondin type 1 motif, 15 11q25 16.9 parous promoter CHAT NM_020549 choline acetyltransferase 10q11.2 4.7 parous promoter LHFPL4 NM_198560 lipoma HMGIC fusion partner-like 4 3p25.3 2.5 parous promoter PANX2 NM_052839 pannexin 2 22q13.33 5 parous promoter LOC85390 NR_001454 NA NA 4.4 parous promoter FLT3 NM_004119 fms-related tyrosine kinase 3 13q12 2.3 parous promoter PODN NM_153703 podocan 1p32.3 2.9 parous promoter SBK1 NM_001024401 SH3-binding domain kinase 1 16p11.2 2.8 parous promoter GAD1 NM_013445 glutamate decarboxylase 1 (brain, 67 kDa) 2q31 2.4 parous promoter FAM54B NM_001099625 family with sequence similarity 54, member B 1 p36.11 20.9 parous promoter CDT1 NM_030928 chromatin licensing and ONA replication factor 1 16q24.3 3.6 parous promoter ZNF28 NM_006969 zinc finger protein 28 19q13.41 2.2 parous promoter PCBD2 NM_032151 pterin-4 alpha-carbinolamine dehydratase/d imenzation cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 5q31.1 3.2 parous promoter RIMS4 NM_182970 regulating synaptic membrane exocytosis 4 20q13.12 2.3 parous promoter FBX044 NM_183412 F-box protein 44 1p36.21 4.6 parous promoter GPRIN1 NM_052899 G protein regulated inducer of neurite outgrowth 1 5q35.2 2.4 parous promoter C5orf38 NM_178569 chromosome 5 open reading frame 38 5p15.33 2.7 parous promoter MAP6 NM_033063 microtubule-associated protein 6 11q13.5 2.6 parous promoter PAQR4 NM_152341 progestin and adipoQ receptor family member IV 16p13 19.4 parous promoter ASGR1 NM_001671 asialoglycoprotein receptor 1 17p13-p11 3.8 parous promoter TPD52L2 NM_003288 tumor protein D52-like 2 20q13.2-q13.3 2.6 parous promoter PRKAR1B NM_002735 protein kinase, cAMP-dependent, regulatory, type I, beta 7pter-p22 2.3 parous promoter CHRNA3 NM_000743 cholinergic receptor, nicotinic, alpha 3 15q24 24.3 parous promoter GHSR NM_198407 growth hormone secretagogue receptor 3q26.31 2.4 parous promoter FMN2 NM_020066 formin 2 1q43 21.9 parous promoter TRAFD1 NM_006700 TRAF-type zinc finger domain containing 1 12q 17.3 parous promoter KIF1A NM_004321 kinesin family member 1A 2q37.2 2.5 parous promoter SGK1 NM_005627 serum/glucocorticoid regulated kinase 1 6q23 2.6 parous promoter RAB11FIP4 NM_032932 RAB11 family interacting protein 4 (class II) 17q11.2 6.1 parous promoter ATP6V1E1 NM_001696 ATPase, H+ transporting, lysosomal 31 kDa, V1 subunit E1 22pter-q11.2 2.4 parous promoter DDX51 NM_175066 DEAD (Asp-Glu-AJa-Asp) box polypeptide 51 12q24.33 6.3 parous promoter PLXNA4 NM_001105543 plexin A4 7q32.3 3.5 parous promoter FAM128B NM_025029 (amity with sequence similarity 128, member B 2q21.1 6.2 parous promoter TMTC4 NM_001079669 transmembrane and tetratricopeptide repeat containing 4 13q32.3 3.8 parous promoter EMP2 NM_001424 epithelial membrane protein 2 16p13.2 2.6 parous promoter DDTL NM_001084393 D-dopachrome tautomerase-like 22q11.23 3.9 parous promoter PDE4A NM_001111307 phosphodiesterase 4A, cAMP-spedfic (phosphodiesterase E2 dunce homolog, Drosophila) 19p13.2 3.1 parous promoter LOC729375 NR_024252 NA NA 5.4 parous promoter AGGF1 NM_018046 angiogenic (actor with G patch and FHA domains 1 5q13.3 3.1 parous promoter AKR1CL2 NM_001040177 NA NA 5.2 parous promoter FLJ10661 NR_024362 NA NA 7.3 parous promoter CEP57 NM_014679 centrosomal protein 57 kDa 11q21 7.5 parous promoter DIP2C NM_014974 DIP2 disco-interacting protein 2 homolog C (Drosophila) 10p 15.3 2.8 parous promoter IGSF3 NM_001007237 immunoglobulin supertamily, member 3 1p13 2.7 parous promoter LRRC27 NM_030626 leucine rich repeat containing 27 10 6 parous promoter ERF NM_006494 Ets2 repressor (actor 19q13 4.1 parous promoter PRELID1 NM_013237 PRELI domain containing 1 5q35.3 2.1 parous promoter EZR NM_003379 eznn 6q25.3 2.6 parous promoter BMP6 NM_001718 bone morphogenetic protein 6 6p24-p23 3 parous promoter NOC4L NM_024078 nucleolar complex associated 4 homolog (S. cerevisiae) 12q24.33 6.3 parous promoter SEC31B NM_015490 SEC31 homolog B (S. cerevisiae) 10q24.32 2.4 parous promoter GPR135 NM_022571 G protein-coupled receptor 135 14q23.1 2.7 parous promoter UCKL1 N M 017859 uridine-cytidine kinase 1-like 1 20 2.4 parous promoter SNORD22 NR_000008 small nucleolar RNA, C/D box 22 11q13 4.6 parous promoter SNORD25 NR_002565 small nucleolar RNA, C/D box 25 11q13 4.6 parous promoter SNORD27 NR_002563 small nucleolar RNA, C/D box 27 11q12.3 4.6 parous promoter SNORD26 NR_002564 small nucleolar RNA, C/D box 26 11q12.3 4.6 parous promoter SNORD29 NR_002559 small nucleolar RNA, C/D box 29 11q12.3 4.6 parous promoter IQWD1 NM_001017977 NA NA 5.3 parous promoter SLC9A3R1 NM_004252 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 17q25.1 2.8 parous promoter SCAMP1 NM_004866 secretory earner membrane protein 1 5q14.1 2.4 parous promoter TERC NR_001566 telomerase RNA component 3q26.2 2.7 parous promoter FOXRED2 NM_024955 FAD-dependent oxidoreductase domain containing 2 22q12.3 3.7 parous promoter TMEM55B NM_001100814 transmembrane protein 55B 14q11.1 2.8 parous promoter C9orf66 NM_152569 chromosome 9 open reading frame 66 9p24.3 −3.2 parous promoter C9orf66 NM_152569 chromosome 9 open reading frame 66 9p24.3 3.2 parous promoter MSX1 NM_002448 msh homeobox 1 4p16.2 2.7 parous promoter MSX1 NM_002448 msh homeobox 1 4p16.2 2 parous promoter 38239 NM_144710 NA NA 2.9 parous promoter ULK1 NM_003565 unc-51-like kinase 1 (C. elegans) 12q24.3 5.4 parous promoter MAT2A NM_005911 methionine adenosyltransferase II, alpha 2p11.2 4.1 parous promoter CARD10 NM_014550 caspase recruitment domain family, member 10 22q13.1 4.8 parous promoter MMD2 NM_001100600 monocyte to macrophage differentiation-associated 2 7p22 2.5 parous promoter HSPB9 NM_033194 heat shock protein, alpha-crystallin-related, B9 17q21 2.8 parous promoter CRLS1 NM_019095 cardiolipin synthase 1 20p13-p12.3 7.4 parous promoter PRICKLE3 NM_006150 prickle homolog 3 (Drosophila) Xp11.23 2.2 parous promoter HIST1H3G NM_003534 histone cluster 1, H3g 6p22.1 2.2 parous promoter SLC7A5P1 NR_002593 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 1 16p11.2 2.6 parous promoter TMBIM1 NM_022152 transmembrane BAX inhibitor motif contaming 1 2q35 2.6 parous promoter RAB24 NM_130781 RAB24, member RAS oncogene family 5q35.3 2.1 parous promoter FAM43A NM_153690 family with sequence similarity 43, member A 3q29 2.2 parous promoter SNORD30 NR_002561 small nucleolar RNA, C/D box 30 11q12.3 4.6 parous promoter SNORD31 NR_002560 small nucleolar RNA, C/D box 31 11q12.3 4.6 parous promoter SLC2A4RG NM_020062 SLC2A4 regulator 20q13.33 2.2 parous promoter MBD4 NM_003925 methyl-CpG binding domain protein 4 3q21.3 4 parous promoter REC8 NM_005132 REC8 homolog (yeast) 14q11.2- 2.2 parous promoter CREB3L1 NM_052854 cAMP responsive element binding protein 34 ike 1 11q11 2.2 parous promoter SCN1B NM_199037 sodium channel, voltage-gated, type I, beta 19 3.8 parous promoter ADARB2 NM_018702 adenosine deaminase, RNA-specific, B2 (RED2 homolog rat) 10p 15.3 3.3 parous promoter SNORD28 NR_002562 small nucleolar RNA, C/D box 28 11q12.3 4.6 parous promoter ATP6V1C2 NM_144583 ATPase, H+ transporting, lysosomal 42 kDa, V1 subunit C2 2p25.1 3.1 parous promoter BZW1 NM_014670 basic leuane zipper and W2 domains 1 2q33 3.9 CD44+ CD44+ CD44+ CD44+ CD44+ CD44+ Distance log2 Ration NCC N35 N48 N37 N39 N40 BssHll region from TSS 4.07643837 94.7 32 16.7 1 3 4.5 chr14:30744891-30746974 508 −1.2390492 164.3 197.4 123 489.2 320.9 334 chr13:27439454-27440249 1466 1.13421154 543.1 636.8 431 340.8 287.1 106 chr13:27441173-27442153 −346 2.13832149 794.7 742.5 368.2 211.2 138.8 82.8 chr14:94855880-94856921 −402 2.17130096 316.7 243.3 384.1 97 58.1 54.5 chr13:45858089-45859877 653 2.45929043 211.6 104.3 195 33.1 38.6 21.2 chr5:140711147-140713193 2159 1.4263989 296 300.3 143.1 97.5 91.3 86.3 chr15:73923552-73924210 1027 2.60178012 56.2 32 32.6 4.9 2.4 12.6 chr1:1554278-1555040 −2763 1.86545184 953.1 878.7 789.2 200.8 420.6 97.9 chr5:140756239-140758980 −269 1.89932454 982.7 675.7 1927 185.5 594.3 181.2 chr9:137992213-137993082 400 2.33723389 1707.8 1532.2 2029 432.8 522 87.8 chr8:23622667-23624110 −3521 2.11442989 59.2 37.5 41 17.3 5.9 8.6 chr5:160905809-160906316 1646 1.71920847 381.8 314.2 644.4 99.4 272.9 34.8 chr2:27340087-27341044 −1101 4.33038967 26.6 12.5 29.3 1 2.4 0 chr16:3108224-3110264 −3644 2.20389436 6868.2 4561.9 4474 416 2939 96.9 chr17:2153131-2155320 −406 2.20389436 6868.2 4561.9 4474 416 2939 96.9 chr17:2153131-2155320 −406 0.39645801 642.3 481.1 512.2 432.3 415.2 395.1 chr11:64402210-64403371 −23 4.47638918 185 159.9 40.2 5.4 1.8 10.1 chr19:41397170-41398384 434 0.94337798 1907.6 1704.6 1577 1491 881.4 326 chr11:550320-551402 −82 1.43517748 5065.7 3905.6 3787 963.6 3564 190.7 chr4:7094697-7096949 −194 2.90197131 668.9 743.9 138.9 64.3 101.4 41.9 chr3:64646344-64647962 1252 0.43262445 396.6 344.8 378.3 311.6 288.9 229.1 chr1:12598746-12602700 −316 2.54457606 1851.3 869 1232 90.5 578.3 8.6 chr22:17273887-17274766 591 1.21171866 674.8 748 417.6 379.4 330.4 84.8 chr19:14044297-14045121 −111 1.26728908 959 638.2 610.1 250.3 443.7 223 chr13:49595808-49596680 1434 1.65526095 282.7 172.4 179.9 79.6 77.1 44.9 chr7:86618712-86620894 −56 2.54946382 219 201.6 534.8 27.2 116.3 19.7 chr16:52879366-52881357 −2482 3.26086657 646.7 399 124.7 48.5 53.4 20.2 chr15:76517345-76518795 498 2.00727717 142.1 118.2 57.7 20.3 39.1 19.7 chr19:49972190-49972604 −568 2.19682886 1476.9 1608.7 619.3 354.2 356.5 97.4 chr19:61344489-61345629 692 1.81184951 1553.9 1733.8 1020 283.4 736.7 206.9 chr19:1156511-1157912 414 1.41955645 760.7 780 718.9 444.2 269.3 131.2 chr17:26445310-26446012 −459 2.48307962 1589.4 1001.1 1426 315.1 307.9 95.4 chr20:1822037-1824093 253 1.74188805 2687.5 2205.2 2604 327 1654 259.9 chr11:95161234-95165177 −603 2.60142588 4319.8 3431.5 3107 314.1 1383 92.3 chr17:7965768-7968799 −4698 0.83682891 87.3 98.7 97.1 66.3 29.1 63.1 chr17:68700084-68700700 −375 1.96903854 2299.8 1878.4 2202 318.1 1237 74.2 chr19:54006815-54008403 −1496 2.41026826 396.6 386.5 183.3 72.7 85.4 23.7 chr2:176656409-176657300 82 3.44955599 393.7 267 678.7 21.3 77.1 24.2 chr8:88955805-88956373 −677 3.28141294 25.2 16.7 84.5 4 6.5 2.5 chr7:6019617-6020056 −4573 3.10582705 358.1 162.7 60.3 18.3 42.1 7.1 chr4:13159045-13160580 −1266 1.16376931 825.8 838.4 639.4 453.1 340.5 234.6 chr10:134451511-134452709 −2583 2.0801188 2514.3 1914.6 1249 377.4 841.7 123.6 chr15:83326397-83327052 516 1.37066821 62.2 57 56.9 32.2 10.7 25.2 chr8:26778401-26778599 339 1.91900676 739.9 818.9 231.8 203.8 188 81.7 chr8:26779893-26781465 −1840 0.96933569 338.9 357.3 379.1 221.6 112.1 215.5 chr6:86409192-86410070 115 2.12151029 3809.3 2601.4 2759 440.8 1310 356.2 chr17:7195418-7196997 276 0.43072969 334.5 390.7 393.3 307.2 296 226.6 chr19:13877921-13878604 −353 1.05428863 74 62.6 142.3 43.5 43.9 46.9 chr11:46895205-46896504 798 2.75798674 77 34.8 97.9 6.4 19 5.6 chr6:11222075-11222398 −2291 1.89986521 3087.1 2073.1 3106 431.9 1628 154.9 chr14:104332624-104334290 −2474 4.73164059 930.9 731.3 104.6 28.2 26.7 11.6 chr19:56766276-56767122 357 1.21744745 68.1 73.7 91.2 32.2 19.6 48.4 chr11:124239737-124240683 −281 0.88849082 467.6 511.7 395.8 322 287.1 133.7 chr5:150612381-150613406 88 2.52531788 3386 1886.8 2763 415 824.5 156.4 chr16:73365348-73366152 472 1.67023079 204.2 189.1 263.6 72.2 64.1 70.1 chr1:114498910-114500564 −1742 1.68455752 2589.8 1473.8 2362 504.6 1387 107.5 chr7:106596535-106597485 315 0.77552029 541.6 574.2 610.9 358.1 497.7 152.9 chr18:12691943-12692545 459 2.08205672 1589.4 1255.5 964.1 84.1 676.2 139.3 chr8:4836951-4839344 1589 1.9452437 1531.7 679.9 1702 338.9 437.2 240.2 chr3:130323020-130324063 −232 1.2444307 229.4 169.6 157.3 88.5 118 28.3 chr12:68038974-68040548 −37 2.09287369 920.5 545 1146 152.4 328 131.7 chr5:52810539-52812441 −861 4.47638918 185 159.9 40.2 5.4 1.8 10.1 chr19:41397170-41398384 49 1.41749963 156.9 154.3 333.9 48 106.2 87.3 chr12:75796608-75797339 −43 1.84665312 500.2 424.1 320.5 133.6 138.8 73.7 chr16:65774170-65776940 −171 1.18099437 692.6 709.1 672 440.8 328 145.8 chr2:95055264-95056998 926 1.87751599 85.8 86.2 159.8 38.1 28.5 23.7 chr4:145785057-145785855 −1166 −2.2871291 41.4 50.1 13.4 180.1 93.7 238.2 chr6:108689120-108689745 −276 1.86049551 423.3 408.8 215.9 89 147.1 52.5 chr6:108689869-108690628 −1092 2.18080261 620.1 560.3 197.5 161.8 83.6 58.5 chr16:56616536-56617374 173 1.44405639 50.3 50.1 53.6 25.2 3.6 27.8 chr4:185982474-185984829 558 2.60178012 56.2 32 32.6 4.9 2.4 12.6 chr1:1554278-1555040 −3362 0.75611816 133.2 162.7 143.9 97.9 57.5 105 chr11:118443496-118444178 135 2.84251816 1472.5 1494.7 297.1 156.8 199.9 98.4 chr11:69601192-69602727 −96 0.94337798 1907.6 1704.6 1577 1491 881.4 326 chr11:550320-551402 −588 1.94914997 1561.3 1026.1 1633 152.4 851.2 89.3 chr1:238322032-238324042 1230 2.51182312 152.4 93.2 106.3 25.7 17.8 18.2 chr4:158111268-158113397 −336 0.43072969 334.5 390.7 393.3 307.2 296 226.6 chr19:13877921-13878604 211 1.9699138 4327.2 2620.9 3886 494.2 2065 205.9 chr16:2954093-2955587 623 1.81899389 37 51.4 48.5 16.8 8.9 13.1 chr12:27823552-27824530 −412 2.09111406 312.3 216.9 212.6 29.7 132.3 12.1 chr11:67649906-67650014 −4526 1.82624974 2844.4 960.8 1552 499.6 688.1 322.9 chr22:49368074-49369099 −326 1.4556739 833.2 816.2 564.9 195.4 482.2 129.7 chr2:27485791-27486387 −89 1.07298049 951.6 948.2 697.1 526.8 447.2 260.4 chr17:72045217-72046115 −289 0.72977221 762.1 720.2 1005 669.3 642.4 188.2 chr3:127906124-127906929 719 0.85005869 307.8 283.6 318.9 212.7 170.2 122.1 chr7:150554475-150555913 56 1.21194376 189.4 201.6 127.2 87.6 86.6 49.5 chr6:100069122-100069785 520 2.48581949 2394.5 1847.8 1270 110.8 768.7 104.5 chr10:102096092-102098450 510 1.43517748 5065.7 3905.6 3787 963.6 3564 190.7 chr4:7094697-7096949 −233 1.31740081 119.9 139 313.8 108.8 74.1 46.9 chr1:59021217-59022365 582 1.57311192 828.7 617.3 615.1 236.9 268.1 187.7 chr8:73149260-73150642 422 −3.9093338 10.4 1.4 0 24.2 35 118.1 chr10:72638544-72639616 −3223 2.76749439 288.6 173.8 230.1 20.8 61.7 19.2 chr10:72642748-72644383 1262 2.85613216 1127.7 666 1326 143.5 204 83.3 chr18:19420303-19421136 −251 0.86385674 611.2 731.3 528.9 397.7 272.3 358.3 chr22:18687509-18688666 −479 2.44791366 220.5 222.5 249.4 79.1 26.1 21.7 chr1:225572365-225573595 −531 0.77552029 541.6 574.2 610.9 358.1 497.7 152.9 chr18:12691943-12692545 −819 0.91407792 404 447.7 360.7 312.1 231.9 99.4 chr14:73775715-73776242 51 2.28586402 2064.5 1619.8 1471 285.4 681 90.8 chr14:73776242-73777614 1001 1.54977719 1508 1466.9 828.5 385.4 718.9 194.8 chr4:5940892-5942077 −268 1.24569492 537.2 479.7 524.7 380.4 207.6 62.1 chr9:114552251-114553102 −278 2.10586792 330 339.3 358.2 81.6 122.8 34.3 chr5:38881231-38882812 129 2.98682461 79.9 50.1 44.4 14.8 4.7 2.5 chr21:44598675-44599100 976 1.13670774 987.1 818.9 731.4 583.2 399.2 171.6 chr11:63808414-63810217 −591 2.78000667 449.9 439.4 323 126.6 29.7 20.2 chr17:44051262-44052535 −4598 2.54731521 167.2 84.8 69.5 16.8 13 25.2 chr16:23755091-23755635 563 2.04626173 266.4 168.2 154.8 38.1 65.2 39.4 chr18:55039466-55040756 1732 2.77760758 362.6 148.8 467.8 54.4 51.6 36.8 chr17:43975912-43977270 801 −1.9068906 20.7 43.1 31.8 86.6 74.1 197.8 chr9:132803789-132804431 −52 1.06518919 1314.1 1337.6 1214 745.5 872.5 229.6 chr9:132804431-132805826 −1070 2.28391404 668.9 421.3 775 162.3 170.2 50.5 chr16:88516590-88518518 309 2.12151029 3809.3 2601.4 2759 440.8 1310 356.2 chr17:7195418-7196997 −3013 2.12681161 661.5 707.7 198.3 136 124 98.9 chr1:42617768-42619192 −574 2.47373108 171.7 175.2 53.6 25.7 13.6 32.8 chr6:26306989-26307765 −388 1.86545184 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33 chr5:115179218-115179883 754 1.38755196 619 422 848 337 171 214 chr9:137992213-137993082 400 0.81096618 164 194 142 83 95 107 chr16:82959484-82959722 −30 0.82579527 118 133 123 63 51 97 chr9:115077683-115077844 −31 1.15121881 210 203 200 151 93 32 chr2:27340087-27341044 −1101 3.36074734 83 38 105 22 0 0 chr17:45562776-45563694 −1069 0.98325674 82 73 102 38 41 51 chr1:3807324-3807550 −728 1.00998409 113 108 69 47 51 46 chr18:26935930-26936675 84 0.75647825 140 138 119 96 62 77 chr17:45008485-45009430 480 0.97182933 281 362 422 205 119 219 chr8:38363348-38363624 −4539 1.74768476 1160 653 1159 495 227 163 chr22:17273887-17274766 591 0.61397095 131 149 147 80 98 101 chr1:226394543-226395184 259 −0.5027242 120 130 129 160 174 203 chr6:86408184-86408678 1315 0.78700628 371 390 295 256 167 189 chr6:86409192-86410070 115 0.67807191 121 175 120 94 74 92 chr5:2804525-2805526 −256 1.48112669 60 85 56 21 22 29 chr1:166171964-166172050 −150 1.28149092 992 1112 1027 522 406 360 chr17:7965768-7968799 −4698 1.0957324 1200 1064 929 612 434 448 chr17:7195418-7196997 276 0.64341784 198 216 203 125 121 149 chr20:34005027-34005915 371 1.63941028 21 21 39 3 13 10 chr3:159304591-159304760 −1155 1.5360529 89 154 105 26 58 36 chr7:23686138-23687515 553 0.63148678 189 264 193 153 102 162 chr20:61838942-61839996 1048 0.97239134 615 653 647 384 257 335 chr19:61344489-61345629 692 0.60550736 1005 844 1086 571 665 693 chr11:95161234-95165177 −603 0.79970135 177 192 148 102 72 123 chr12:48737132-48737875 −250 1.67377177 315 189 166 54 69 87 chr11:77411177-77411941 409 0.70143916 132 117 112 78 73 71 chr9:92603631 -92603791 −121 0.98325674 82 73 102 38 41 51 chr1:3807324-3807550 610 NA 9 4 5 0 0 0 chr20:42590341 -42591024 −3167 2.15959364 143 122 222 42 16 51 chr5:132193549-132194720 −4233 1.38082178 44 48 33 11 15 22 chr5:15552531-15553771 −153 1.52256596 72 57 52 26 9 28 chr17:77453183-77453445 −131 0.53859254 66 69 64 40 50 47 chr11:69165352-69165427 336 1.30753187 129 127 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145 127 86 39 33 68 chr1:21982035-21982304 106 0.85626452 68 76 66 34 35 47 chr17:54763227-54764337 −52 1.22831726 647 545 516 263 201 265 chr10:102096092-102098450 510 0.70948486 80 102 78 47 50 62 chr3:161955885-161956835 −329 2.60203601 19 44 22 3 2 9 chr9:97824691 -97825096 −1035 0.88896869 102 114 84 56 48 58 chr12:8434349-8434620 131 1.34169135 43 43 61 16 19 23 chr3:130641694-130641738 59 1.48377268 263 145 115 82 60 45 chr19:8020835-8021781 −2625 0.85895612 202 171 182 106 60 140 chr6:146097340-146098325 852 1.84799691 53 60 49 5 18 22 chr8:19216086-19216897 1005 0.7695792 456 664 416 293 248 360 chr14:22904148-22905560 −172 1.08861439 156 204 110 83 68 70 chr11:566245-567005 140 0.65284497 261 234 310 145 185 182 chr22:22645930-22646097 667 1.02126862 66 76 63 20 34 47 chr7:101244064-101245314 −2912 0.71318821 118 128 95 61 70 77 chr1:35431494-35432145 −489 1.09085343 70 71 72 15 43 42 chr11:122437240-122438400 −2430 0.85333035 80 87 104 40 50 60 chr9:34579477-34579803 82 1.0957324 1200 1064 929 612 434 448 chr17:7195418-7196997 −3013 0.47212669 570 466 562 418 417 317 chr6:26379249-26381182 −967 0.83338977 726 606 653 439 245 430 chr3:124228291 -124230592 −175 0.86302613 438 522 526 388 198 231 chr14:76297922-76298830 389 1.30753187 129 127 93 59 30 52 chr11:62380031-62380122 −17 0.82579527 118 133 123 63 51 97 chr9:115077683-115077844 −73 1.12066253 197 180 134 110 43 82 chr5:136861747-136863131 478 0.89649542 131 122 110 71 49 75 chr10:50488433-50488647 188 0.61470984 168 215 156 129 94 129 chr19:53466041-53467145 128 1.10433666 60 46 66 26 30 24 chr14:76857390-76857632 −533 0.82554922 250 268 260 198 126 115 chr4:17632329-17633100 −231 1.28149092 992 1112 1027 522 406 360 chr17:7965768-7968799 844 1.34934686 384 379 804 250 157 208 chr7:100126892-100128257 −2768 0.81665448 130 176 122 101 53 89 chr3:130228831 -130229098 −3017 1.78849589 22 26 28 3 11 8 chr7:27208596-27209003 −2549 1.59500617 415 418 176 136 80 118 chr16:48744364-48745279 −747 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38 27 47 chr5:134268268-134268809 −170 1.45768184 232 250 136 63 49 113 chr20:42871701-42872255 348 1.90399265 486 481 152 106 82 111 chr1:11635345-11637981 −355 0.75942044 86 93 80 50 41 62 chr5:175969265-175969468 371 0.67807191 121 175 120 94 74 92 chr5:2804525-2805526 −236 1.08530731 157 156 105 81 60 56 chr11:75055973-75057060 611 0.98326483 1348 1198 1568 875 761 445 chr16:2954093-2955587 −4502 1.0340932 438 248 256 195 107 158 chr17:7021767-7022604 1422 0.63173319 240 241 193 161 117 157 chr20:61966516-61966776 −387 0.44170545 159 140 156 113 116 106 chr7:717666-718276 688 1.04663109 823 641 674 384 302 349 chr15:76698191 -76700189 1187 1.00826762 76 50 49 30 22 35 chr3:173647786-173648259 875 1.08934257 548 590 494 297 211 259 chr1:238322032-238324042 1230 1.51402659 508 326 297 164 89 143 chr12:111047454-111049040 484 1.4150375 95 128 65 39 21 48 chr2:241408252-241409207 −432 0.79851813 1004 931 954 853 434 374 chr6:134540935-134541770 −3625 0.82515472 411 518 437 318 167 286 chr17:26741966-26743420 −74 0.79585928 89 82 79 59 24 61 chr22:16490793-16491191 596 1.07613107 130 170 128 62 59 82 chr12:131194792-131194986 −56 0.79501826 98 77 87 49 50 52 chr7:131912984-131913173 −1215 0.69168818 462 363 346 264 207 254 chr2:130655386-130656106 −426 0.93920832 126 132 137 62 53 91 chr13:100124784-100125592 −84 0.43568181 220 193 197 145 147 159 chr16:10581752-10582511 −91 0.65284497 261 234 310 145 185 182 chr22:22639606-22639773 664 0.62890585 142 143 165 95 86 110 chr19:10392320-10392440 48 1.0850361 114 97 86 45 42 53 chr3:131312631-131313003 149 0.74639501 99 112 96 62 50 71 chr5:76362205-76362347 289 1.43942166 60 68 51 25 27 14 chr10:4859083-4859340 810 1.27665402 114 95 89 39 36 48 chr8:8123536-8123907 220 0.60550736 1005 844 1086 571 665 693 chr11:95161234-95165177 −84 1.06667104 59 50 46 25 18 31 chr10:724666-725492 529 0.91600991 213 342 179 133 107 149 chr1:117010995-117012037 321 0.90098999 221 271 240 96 160 136 chr10:133994726-133995657 −502 0.95015145 1638 1315 1655 1181 669 535 chr19:47448945-47450989 1182 0.53546054 162 184 141 109 108 119 chr5:176662893-176663422 −283 0.9090915 86 86 74 40 35 56 chr6:159159334-159159497 −87 1.28010792 148 119 73 34 53 53 chr6:7673027-7673366 1187 1.07613107 130 170 128 62 59 82 chr12:131194792-131194986 −56 1.91358525 73 55 34 22 6 15 chr10:102269034-102270305 −84 0.57678857 135 161 144 92 95 108 chr14:59000690-59000819 1058 1.01088832 52 41 40 20 19 27 chr20:62058167-62058211 23 1.30753187 129 127 93 59 30 52 chr11:62380031 -62380122 −2993 1.30753187 129 127 93 59 30 52 chr11:62380031 -62380122 −397 1.30753187 129 127 93 59 30 52 chr11:62380031 -62380122 −945 1.30753187 129 127 93 59 30 52 chr11:62380031 -62380122 −662 1.30753187 129 127 93 59 30 52 chr11:62380031-62380122 −2060 1.48112669 60 85 56 21 22 29 chr1:166171964-166172050 −524 0.66209197 146 125 142 94 70 97 chr17:70255807-70257051 51 1.13573804 126 237 127 68 54 101 chr5:77692103-77692718 316 0.84883593 123 122 99 75 47 69 chr3:170965093-170965688 152 0.79097263 334 379 294 240 114 228 chr22:35232041-35233363 334 0.57044208 106 138 102 77 80 76 chr14:19999322-19999533 50 −1.1953476 60 86 54 118 151 189 chr9:203667-204892 1614 0.92218047 156 135 124 77 46 96 chr9:204976-205591 610 2.14886339 39 41 22 5 12 6 chr4:4906635-4908946 −4502 1.19264508 88 84 52 30 40 28 chr4:4911756-4912477 −176 0.84036477 226 244 171 125 94 139 chr2:109728691 -109729896 −221 1.09153355 155 164 169 67 55 107 chr12:130944720-130945499 −122 1.52606881 73 85 58 24 16 35 chr2:85620259-85620455 559 0.92599942 100 85 81 49 40 51 chr22:36245151-36245781 −310 0.95750792 648 466 1094 348 375 414 chr7:4965186-4966721 −583 0.80346101 174 219 162 100 86 132 chr17:37526311-37526846 −1816 1.30975338 87 125 83 37 38 44 chr20:5934892-5935798 607 1.07528813 36 49 33 18 15 23 chrX:48929692-48929843 −47 0.47212669 570 466 562 418 417 317 chr6:26379249-26381182 −624 1.55393561 112 103 61 38 12 44 chr16:29532460-29532749 −65 0.87382289 133 143 96 65 64 74 chr2:218865083-218865357 304 0.53546054 162 184 141 109 108 119 chr5:176662893-176663422 193 0.88308225 89 118 101 42 54 71 chr3:195889201 -195889393 1387 1.30753187 129 127 93 59 30 52 chr11:62380031 -62380122 −2296 1.30753187 129 127 93 59 30 52 chr11:62380031 -62380122 −2635 0.63148678 189 264 193 153 102 162 chr20:61838942-61839996 −2185 1.34169135 43 43 61 16 19 23 chr3:130641694-130641738 −174 3.20013961 287 241 51 37 7 19 chr14:23710566-23712370 395 0.5071557 121 143 124 78 100 95 chr11:46255944-46256479 408 0.78407526 498 541 1005 336 429 422 chr19:40212455-40213564 −364 1.6891735 93 129 65 27 18 44 chr10:1769176-1769342 459 1.30753187 129 127 93 59 30 52 chr11:62380031 -62380122 −1333 1.17241455 185 146 104 77 48 68 chr2:10778819-10779497 −67 0.80252177 366 403 274 221 168 209 chr2:201384119-201384455 −604

TABLE 15 Genes that Are Differentially Methylated between Nulliparous and Parous CD44+ Breast Epithelial Cells SAGE-seq ChIP-seq MSDK-seq Nuliiparous (NP) Parous (P) NP P NP P NP P expression Fold log10 CD44+ CD44+ CD44+ CD44+ CD44+ CD44+ CD44+ CD44+ GeneBody GeneBody Pro-motor Pro-moter Gene Symbol pattern Change p-value (p-val.) Ranking N48 N58 N43 N37 N39 N40 N74 N66 NP Met Met Met Met LOC100128822 high in NP −4.9 0.049995909 −1.3 12766 2 6 14 2 2 2 NA NA N N N N PEX19 high in NP −2.3 0.049982271 −1.3 12767 48 60 40 28 14 14 N N N N N N HOPX high in NP −3.9 0.049959768 −1.3 12768 350 49 39 7 8 33 N N N N N N MSH6 high in NP −2.2 0.049939311 −1.3 12769 24 83 45 19 15 19 N N N N N N TNPO1 high in NP −3.2 0.049926355 −1.3 12770 76 325 209 85 79 78 N N N N P N PACRGL high in NP −4.8 0.04989226 −1.3 12771 8 20 23 8 8 8 N N N N N N ITGA7 high in NP −3.1 0.049863621 −1.3 12772 288 207 86 58 35 64 N N N N N N GTPBP8 high in NP −4.9 0.04979134 −1.3 12773 4 8 20 4 4 4 N P N N N N ATG4A high in NP −2.6 0.049777702 −1.3 12774 12 16 19 6 8 6 N N N N N N CHRDL1 high in NP −3.3 0.049734061 −1.3 12775 152 172 75 36 20 67 P P N N N N DDB2 high in NP −2.4 0.04962223 −1.3 12776 42 33 17 8 8 13 N N N N N N SBDSP high in NP −2.9 0.049466758 −1.3 12777 NA NA NA NA NA NA N N N N P N WAPAL high in NP −4.5 0.049459939 −1.3 12778 38 231 180 35 38 51 N N N N N N AHSA2 high in NP −2.8 0.04945312 −1.3 12779 7 38 76 7 7 10 N N N N N N KRAS high in NP −2.7 0.049425162 −1.3 12780 121 288 262 85 104 96 N N N N N N IRX6 high in NP −5.4 0.049380839 −1.3 12781 3 11 6 3 3 3 P N N N N N CHRAC1 high in NP −2.1 0.049366519 −1.3 12782 153 251 208 105 68 88 N N N N N N EEPD1 high in NP −2.5 0.049341971 −1.3 12783 92 26 47 11 16 14 N N N N N N CDC42BPB high in NP −2.2 0.049289465 −1.3 12784 209 188 261 138 100 85 N N N N N N TTC33 high in NP −2.9 0.049224003 −1.3 12785 9 58 24 9 9 9 N N N N N N GAB1 high in NP −1.9 0.049181043 −1.3 12786 28 47 43 24 21 21 N N N N N N FAM46B high in NP −2.6 0.049159223 −1.3 12787 131 142 333 45 81 50 N N N N N N MBTPS1 high in NP −2.8 0.049152404 −1.3 12788 65 154 106 71 26 26 N N N N N N SBNO1 high in NP −3.2 0.049106035 −1.3 12789 19 71 56 15 13 21 N N N N N N RNF152 high in NP −2.3 0.049099216 −1.3 12790 47 68 94 29 17 25 N N N N N N PPIA high in NP −2.5 0.049065803 −1.3 12791 193 430 326 141 152 106 N N N N N N SLC25A39 high in NP −2.9 0.048991476 −1.3 12792 14 61 31 12 8 8 N N N N N N SSNA1 high in NP −2.2 0.048975793 −1.3 12793 148 128 160 68 60 22 N N N N N N RPH3AL high in NP −3.0 0.048954654 −1.3 12794 7 17 23 7 7 7 N N N N N N PPM1K high in NP −2.6 0.048915786 −1.3 12795 9 40 38 9 9 12 N N N N N N TCF15 high in NP −3.3 0.048903512 −1.3 12796 281 24 46 18 8 10 P P N N N N CPVL high in NP −3.2 0.048881691 −1.3 12797 3 53 11 3 3 3 P N N N N N TMEM38A high in NP −5.1 0.048874872 −1.3 12798 4 8 16 4 4 4 N N N N N N CLDN8 high in NP −5.2 0.048861916 −1.3 12799 2 7 11 2 2 2 N N N N N N ZNF281 high in NP −4.2 0.048855097 −1.3 12800 24 55 88 23 13 16 N N N N N N HDGFRP3 high in NP −4.9 0.048844869 −1.3 12801 19 63 66 12 11 6 N N N N N N DDX50 high in NP −1.9 0.04883805 −1.3 12802 13 32 20 6 6 6 N N N N N N MRPS24 high in NP −3.0 0.048831231 −1.3 12803 308 708 1048 234 223 171 N N N N N N MLST8 high in NP −2.7 0.048812138 −1.3 12804 18 19 23 10 6 6 NA NA N N N N PIGK high in NP −3.9 0.048793045 −1.3 12805 284 112 38 24 25 24 N N N N N N PLTP high in NP −2.4 0.04877327 −1.3 12806 1046 595 986 294 358 411 N N N N N N EIF2S1 high in NP −3.6 0.048743948 −1.3 12807 55 294 220 61 64 38 N N N N N N GBP1 high in NP −3.0 0.048678486 −1.3 12808 106 148 166 24 40 73 N N N N N N ZNF292 high in NP −2.1 0.04866553 −1.3 12809 110 77 119 41 35 53 N N N N N N SSPN high in NP −2.6 0.048652574 −1.3 12810 295 47 43 15 18 21 N N N N N N ABCC1 high in NP −3.2 0.048638936 −1.3 12811 88 296 213 69 84 52 N N N N N N WDR45L high in NP −2.9 0.048632117 −1.3 12812 317 637 899 288 194 214 N N N N N N C18orf8 high in NP −6.5 0.048606205 −1.3 12813 7 148 53 7 12 7 N N N N N N CMTM3 high in NP −3.2 0.048555063 −1.3 12814 693 472 235 99 221 131 N N N N P N UTP14C high in NP −5.2 0.048527105 −1.3 12815 9 14 19 9 9 9 N N N N N N ALOX5 high in NP −5.1 0.048427549 −1.3 12816 5 31 44 5 8 5 N P N N N N CDC42EP4 high in NP −2.5 0.048347085 −1.3 12817 1049 687 621 412 220 460 N N N N N N ATRX high in NP −2.3 0.048254347 −1.3 12818 163 123 138 101 54 59 N N N N N N FAM176A high in NP −3.1 0.048210024 −1.3 12819 6 20 16 6 6 6 N N N N N N DCAF11 high in NP −2.7 0.048177293 −1.3 12820 83 67 71 45 23 21 NA NA N N N N CNNM2 high in NP −1.9 0.048170474 −1.3 12821 225 207 229 104 92 93 N N N N N N PRKD3 high in NP −2.3 0.048123423 −1.3 12822 78 106 76 28 30 42 N N N N N N CEACAM6 high in NP −5.4 0.048021821 −1.3 12823 6 10 14 6 6 6 P P N N N N UQCRQ high in NP −7.6 0.047956359 −1.3 12824 27 290 225 30 18 13 N N N N N N PSMB4 high in NP −4.2 0.0479209 −1.3 12825 345 1407 1730 396 301 128 N N N N N N SPIN3 high in NP −5.2 0.047889533 −1.3 12826 12 30 15 12 12 12 N P N N N N LPL high in NP −2.6 0.047869076 −1.3 12827 187 93 145 71 24 47 N N N N N N KIAA2013 high in NP −2.0 0.047767474 −1.3 12828 324 185 190 87 92 73 N N N N N N OXSR1 high in NP −7.0 0.04774088 −1.3 12829 13 119 87 19 16 13 N N N N P N FAM49A high in NP −4.9 0.047624275 −1.3 12830 3 21 14 3 3 3 N N N N N N LSM6 high in NP −8.4 0.047617457 −1.3 12831 2 51 55 5 2 2 N N N N N N TNFSF12 high in NP −3.3 0.047599727 −1.3 12832 25 16 8 2 2 8 N N N N N N FAM76A high in NP −3.0 0.047565632 −1.3 12833 21 58 33 17 9 9 N N N N N N ELF3 high in NP −5.9 0.047499489 −1.3 12834 39 269 499 31 91 27 N N N N N N ZNF99 high in NP −5.2 0.047485851 −1.3 12835 1 5 18 1 1 1 N N N N N N MAML1 high in NP −2.4 0.047464712 −1.3 12836 34 135 82 28 38 34 N N N N N N SCAMP1 high in NP −2.7 0.047394477 −1.3 12837 105 85 65 24 24 40 N N N P N N EXOC3 high in NP −2.8 0.047384248 −1.3 12838 55 109 129 44 38 16 N N N N N N STARD4 high in NP −2.6 0.047350835 −1.3 12839 18 16 10 9 6 6 N N N N N N MCFD2 high in NP −3.2 0.047306512 −1.3 12840 64 176 183 56 39 51 N N N N N N C19orf20 high in NP −3.3 0.047256052 −1.3 12841 45 42 49 26 10 2 N N N N N N RPPH1 high in NP −5.2 0.0471224 −1.3 12842 34 7 14 10 2 2 N N N N N N TNFAIP1 high in NP −3.2 0.047101262 −1.3 12843 31 68 99 23 23 27 N N N N N N POLR2C high in NP −3.3 0.047094443 −1.3 12844 33 135 114 31 17 11 N N N N N N SLU7 high in NP −2.6 0.047080805 −1.3 12845 79 163 153 67 41 49 N N N N P N UCHL5 high in NP −2.0 0.047022844 −1.3 12846 13 15 24 7 7 7 N N N N N N EARS2 high in NP −2.0 0.046947835 −1.3 12847 30 22 24 13 11 8 N N N N N N YY1 high in NP −3.4 0.046941016 −1.3 12848 94 245 370 45 55 96 N N N N N N RPL22L1 high in NP −5.1 0.046854415 −1.3 12849 2 18 13 2 2 2 N N N N N N LTV1 high in NP −8.6 0.046787589 −1.3 12850 3 53 55 3 6 3 N N N N N N GNL3 high in NP −5.4 0.046757586 −1.3 12851 97 707 383 67 102 65 N N N N N N C15orf28 high in NP −5.1 0.046724855 −1.3 12852 6 44 33 9 6 6 NA NA N N N N ZXDB high in NP −3.5 0.046660075 −1.3 12853 130 393 328 89 79 110 N N N N N N CCL7 high in NP −5.4 0.046653256 −1.3 12854 2 7 18 2 2 2 N N N N N N MST1P2 high in NP −5.4 0.046598023 −1.3 12855 1 5 20 1 1 1 NA NA N N N N EHBP1 high in NP −2.5 0.046542789 −1.3 12856 35 62 49 15 13 24 N N N N N N ROR1 high in NP −2.2 0.046529151 −1.3 12857 148 120 124 40 54 67 N N N N N N OSBPL9 high in NP −5.4 0.046500511 −1.3 12858 17 99 74 14 15 10 N N N N N N BMP4 high in NP −2.8 0.046486874 −1.3 12859 220 144 66 22 22 67 N P N N N N MGC2752 high in NP −2.6 0.046456188 −1.3 12860 41 143 106 59 25 22 NA NA N N N N SELPLG high in NP −4.1 0.046443914 −1.3 12861 27 50 15 11 11 14 N N N N N N RMND5A high in NP −2.4 0.046430276 −1.3 12862 111 179 220 50 62 99 N N N N N N ITGAE high in NP −2.5 0.046387317 −1.3 12863 8 28 36 8 8 8 N N N N N N RB1CC1 high in NP −3.9 0.046377088 −1.3 12864 20 160 117 32 26 28 N N N N P N ZNF181 high in NP −3.1 0.046357995 −1.3 12865 4 22 27 4 4 4 N N N N N N IMMT high in NP −2.8 0.046342994 −1.3 12866 20 67 53 20 12 12 N N N N N N UBE2A high in NP −5.9 0.046320491 −1.3 12867 16 123 76 18 19 19 N N N N N N APLP2 high in NP −2.7 0.046313672 −1.3 12868 7339 5798 3008 2381 1592 1704 N N N N N N MAPKAPK5 high in NP −5.4 0.046291169 −1.3 12869 8 127 58 10 8 11 N N N N N N HNRNPR high in NP −4.8 0.046250256 −1.3 12870 23 128 101 24 24 17 N N N N N N STAP2 high in NP −12.5 0.046174565 −1.3 12871 4 51 44 4 7 4 N N N N N N GOLGA6D high in NP −6.4 0.046143198 −1.3 12872 1 7 7 1 1 1 NA NA N N N N DIABLO high in NP −2.5 0.04612956 −1.3 12873 107 206 142 76 43 40 N N N N N N MBD1 high in NP −3.2 0.046081827 −1.3 12874 9 62 71 18 9 9 N N N N N N ENY2 high in NP −11.5 0.046075009 −1.3 12875 2 79 47 2 2 5 N N N N N N EDIL3 high in NP −1.9 0.046027276 −1.3 12876 15 17 14 9 9 9 P N N N N N AIM1L high in NP −6.6 0.045922946 −1.3 12877 6 13 11 6 6 6 N N N N N N EGR4 high in NP −6.4 0.045916127 −1.3 12878 2 10 7 2 2 2 P P N N P N MIER2 high in NP −4.9 0.045893624 −1.3 12879 30 62 107 13 21 24 N N N N N N SULT1A2 high in NP −5.6 0.045880668 −1.3 12880 3 29 7 3 3 3 N N N N N N S100A10 high in NP −3.9 0.045765428 −1.3 12881 355 2442 2149 163 534 194 N N N N N N SAT1 high in NP −2.8 0.045703375 −1.3 12882 3018 7687 6420 1966 1802 2366 N N N N N N MBD2 high in NP −10.6 0.045696556 −1.3 12883 40 377 403 27 27 34 N N N N N N FMO5 high in NP −4.3 0.045689737 −1.3 12884 13 52 74 7 14 7 N N N N N N KLHL9 high in NP −2.0 0.0456761 −1.3 12885 17 35 42 16 11 11 N N N N N N LIN37 high in NP −5.3 0.045650188 −1.3 12886 4 24 16 4 4 4 N N N N N N TOR1AIP2 high in NP −2.0 0.045643369 −1.3 12887 25 39 59 17 17 17 N N N N N N WDR89 high in NP −3.2 0.045618138 −1.3 12888 8 35 15 8 8 8 N N N N N N TNIP1 high in NP −2.2 0.045590863 −1.3 12889 498 570 740 387 265 145 N N N N N N FASTKD1 high in NP −4.9 0.045584044 −1.3 12890 7 36 38 9 7 7 N N N N N N RHBDF1 high in NP −2.2 0.045471531 −1.3 12891 93 108 173 51 43 33 N N N N N N NINJ2 high in NP −1.9 0.045447665 −1.3 12892 9 6 6 3 3 3 N N N N N N EMP3 high in NP −3.3 0.045434027 −1.3 12893 501 1325 1502 410 364 337 N N N N N N METAP1 high in NP −2.1 0.045337879 −1.3 12894 68 125 85 46 42 34 N N N N N N FAM160A2 high in NP −2.7 0.045211047 −1.3 12895 32 70 60 26 21 21 N N N N N N KLK1 high in NP −6.5 0.04516536 −1.3 12896 162 173 262 10 19 150 N P N N N N RAB25 high in NP −6.3 0.045103307 −1.3 12897 4 9 12 4 4 4 N N N N N N SPATS2L high in NP −2.4 0.045096488 −1.3 12898 103 357 195 70 79 72 NA NA N N N N HAND2 high in NP −2.0 0.044981248 −1.3 12899 22 21 18 6 8 9 N N N N N N STAC high in NP −3.5 0.044878282 −1.3 12900 31 11 19 5 13 5 N N N N N N CTTNBP2NL high in NP −2.4 0.044718718 −1.3 12901 17 48 59 17 20 17 N N N N N N CNOT6L high in NP −2.8 0.044686669 −1.3 12902 124 194 117 48 47 92 N N N N N N ARL6IP1 high in NP −3.2 0.04467985 −1.3 12903 651 1075 974 217 294 554 N N N N N N BLOC1S3 high in NP −2.1 0.044657347 −1.4 12904 90 109 110 51 37 27 N N N N N N BRF2 high in NP −3.6 0.044650528 −1.4 12905 15 47 78 15 4 4 N N N N N P RICTOR high in NP −1.9 0.044614388 −1.4 12906 27 45 58 25 20 20 N P N N N N TMEM206 high in NP −5.5 0.044561882 −1.4 12907 6 27 19 6 6 6 N N N N N N PSMA4 high in NP −4.4 0.044512104 −1.4 12908 58 268 208 53 35 22 N N N N N N EML1 high in NP −2.0 0.044478691 −1.4 12909 24 30 37 16 11 11 N N N N N N C7orf64 high in NP −3.1 0.044465053 −1.4 12910 6 28 41 6 6 6 N N N N N N BNIP3L high in NP −4.3 0.044458234 −1.4 12911 140 882 881 247 57 94 N N N N N N ZNF585A high in NP −2.0 0.044416638 −1.4 12912 10 8 8 4 4 4 N N N N N N C2orf79 high in NP −2.5 0.044409819 −1.4 12913 24 57 52 7 8 17 N N N N N N FAM58A high in NP −7.1 0.044371633 −1.4 12914 6 121 31 6 6 9 N N N N N N PAAF1 high in NP −1.9 0.044364814 −1.4 12915 12 8 7 6 6 6 N N N N N N SERPINB13 high in NP −6.4 0.044263894 −1.4 12916 6 17 11 6 6 6 N N N N N N ISM1 high in NP −4.0 0.044257075 −1.4 12917 23 24 9 7 7 7 NA NA N N N N MAP3K13 high in NP −3.4 0.044241391 −1.4 12918 9 19 44 9 9 9 N N N P N N FOXA1 high in NP −2.9 0.044178657 −1.4 12919 14 24 39 10 8 8 P P N N N N FAM181B high in NP −3.3 0.044165019 −1.4 12920 17 3 9 3 4 1 N N N N N N ARL6IP5 high in NP −2.3 0.044150699 −1.4 12921 414 264 223 107 145 147 N N N N N N ATP1B2 high in NP −3.5 0.044112513 −1.4 12922 421 139 88 67 19 53 N N N N N N TMEM135 high in NP −2.5 0.044063416 −1.4 12923 9 31 31 9 9 9 N N N N N N WDR6 high in NP −3.6 0.044047733 −1.4 12924 74 257 202 69 51 57 N N N N N N GPX2 high in NP −7.3 0.043925673 −1.4 12925 2 9 8 2 2 2 N N N N N N BRAF high in NP −3.0 0.04390658 −1.4 12926 7 19 19 7 7 7 N N N N N N BRD7 high in NP −3.0 0.043899761 −1.4 12927 14 74 34 10 11 8 N N N N N N C10orf57 high in NP −6.1 0.043860211 −1.4 12928 5 20 18 5 5 5 N N N N N N TOLLIP high in NP −2.4 0.043833617 −1.4 12929 197 341 319 117 143 129 N N N N N N CHCHD5 high in NP −2.1 0.043826798 −1.4 12930 38 28 55 13 11 10 N N N N N N KIAA1826 high in NP −6.4 0.043749062 −1.4 12931 6 17 10 6 6 6 N N N N N N FLOT1 high in NP −2.1 0.043724514 −1.4 12932 362 257 237 128 116 95 N N N N N N CASP3 high in NP −3.3 0.043657006 −1.4 12933 9 30 23 9 9 9 N N N N N N GIPC1 high in NP −2.7 0.04363655 −1.4 12934 142 137 194 56 88 27 N N N N N N THAP1 high in NP −5.3 0.043629731 −1.4 12935 2 35 14 2 2 2 N N N N N N SAR1B high in NP −3.3 0.043614047 −1.4 12936 6 33 22 6 6 6 N N N N N N ACER3 high in NP −2.1 0.043584726 −1.4 12937 53 87 74 26 36 33 NA NA N N N N CRLS1 high in NP −4.0 0.043571088 −1.4 12938 18 121 66 22 15 12 N N N N N N CENPV high in NP −5.3 0.04355745 −1.4 12939 4 44 16 4 4 4 N N N N N N FAM108B1 high in NP −2.6 0.043536311 −1.4 12940 153 276 374 76 75 117 N N N N N N FAM164A high in NP −2.0 0.043494715 −1.4 12941 29 16 13 8 8 8 N N N N N N CCNG2 high in NP −2.9 0.043475622 −1.4 12942 255 162 142 52 39 100 N N N N N N HSP90AA1 high in NP −3.1 0.043468803 −1.4 12943 1908 7636 1864 929 722 1560 N N N N N N ATAD1 high in NP −2.6 0.043453802 −1.4 12944 135 109 104 72 38 32 N N N N N N SELENBP1 high in NP −3.4 0.043419707 −1.4 12945 323 68 78 17 28 37 N N N N N N BBX high in NP −2.3 0.043412888 −1.4 12946 156 112 115 74 52 65 N P N N N N SAA4 high in NP −6.3 0.043402659 −1.4 12947 3 8 16 3 3 3 N N N N N N OPN1SW high in NP −6.3 0.043402659 −1.4 12948 4 9 17 4 4 4 N N N N N N PAPD7 high in NP −3.0 0.043321514 −1.4 12949 110 337 194 42 74 99 NA NA N N N N UBE2D1 high in NP −4.1 0.043300375 −1.4 12950 86 279 367 38 44 79 N N N N N N TMEM167B high in NP −2.1 0.043237641 −1.4 12951 71 112 110 47 31 27 N N N N N N SERPINB3 high in NP −6.4 0.043230822 −1.4 12952 1 7 13 1 1 1 N N N N N N TXNL4A high in NP −4.8 0.043224003 −1.4 12953 35 225 130 29 22 17 N N N N P N C9orf86 high in NP −2.4 0.043202182 −1.4 12954 347 365 468 279 154 68 N N N N N N ADAMTS6 high in NP −6.9 0.043171497 −1.4 12955 4 14 9 4 4 4 N N N N N N BRP44L high in NP −5.4 0.043164678 −1.4 12956 6 51 19 6 6 6 N N N N N N FZD1 high in NP −3.0 0.043157859 −1.4 12957 134 135 98 34 42 68 N N N N P N ASS1 high in NP −2.6 0.04315104 −1.4 12958 147 151 274 65 96 16 N N N N N N USP43 high in NP −3.1 0.043123082 −1.4 12959 10 22 22 10 10 10 N P N N P N MEST high in NP −4.2 0.043103989 −1.4 12960 257 191 88 18 86 38 N N N N N N TNNT3 high in NP −6.0 0.042986703 −1.4 12961 32 91 50 6 11 26 N N N N N N BIK high in NP −6.3 0.042951926 −1.4 12962 6 11 22 6 6 6 N P N N N N TPBG high in NP −2.5 0.042930788 −1.4 12963 605 958 635 267 264 471 N N N N N N FAM109B high in NP −2.3 0.042845551 −1.4 12964 97 60 44 23 18 20 N N N N N N CCDC51 high in NP −7.0 0.042818275 −1.4 12965 3 10 11 3 3 3 N N N N N N LOC389033 high in NP −6.4 0.042712581 −1.4 12966 1 7 17 1 1 1 NA NA N N N N CBX3 high in NP −5.0 0.042698943 −1.4 12967 71 258 314 35 60 43 N N N N N N FAM165B high in NP −2.6 0.042655302 −1.4 12968 91 235 139 44 33 57 N N N N N N ZC3HC1 high in NP −5.6 0.042484828 −1.4 12969 5 37 17 5 5 5 N N N N N N FLJ30679 high in NP −5.7 0.042451415 −1.4 12970 4 30 17 4 4 4 NA NA N N N N PBRM1 high in NP −2.1 0.042411865 −1.4 12971 79 94 63 47 29 29 N N N N N N NUDT16L1 high in NP −2.9 0.042384589 −1.4 12972 16 20 20 7 5 8 N N N N N N H2AFY high in NP −2.6 0.042348449 −1.4 12973 528 718 709 306 402 141 N N N N N N CBX4 high in NP −3.7 0.042237982 −1.4 12974 123 124 137 16 27 77 N N N N N N RGL1 high in NP −2.3 0.042225707 −1.4 12975 79 63 52 28 30 21 N N N N N N BATF3 high in NP −2.8 0.042218889 −1.4 12976 14 27 23 3 8 3 N N N N N N ARNTL high in NP −10.4 0.04218343 −1.4 12977 12 96 114 12 15 15 N N N N N N BOD1 high in NP −3.2 0.042176611 −1.4 12978 18 115 61 17 15 15 NA NA N N N N NKRF high in NP −3.6 0.042162973 −1.4 12979 63 85 65 14 17 41 N N N N N N TRIM47 high in NP −2.8 0.041991135 −1.4 12980 62 186 186 59 27 32 N N N N N N RNPS1 high in NP −6.5 0.041972042 −1.4 12981 31 283 278 24 29 35 N N N N N N NPHP3 high in NP −2.1 0.041956359 −1.4 12982 15 47 59 15 18 15 N N N N N N ELOVL3 high in NP −7.0 0.04194954 −1.4 12983 4 10 14 4 4 4 N N N N N P TOP3B high in NP −3.5 0.041920218 −1.4 12984 13 25 30 13 13 13 N N N N N N SNX3 high in NP −19.9 0.041883396 −1.4 12985 12 436 258 14 8 12 N N N N P P KLHL12 high in NP −3.2 0.041869076 −1.4 12986 13 39 37 11 7 7 N N N N N N ATF4 high in NP −2.7 0.041862257 −1.4 12987 1515 3348 3543 607 1265 944 N N N N N N KIAA0114 high in NP −17.6 0.041855438 −1.4 12988 3 124 178 7 3 3 N N N N N N MTERFD1 high in NP −7.7 0.041811797 −1.4 12989 2 12 10 2 2 2 N N N N N N CARD16 high in NP −7.5 0.041804978 −1.4 12990 2 9 11 2 2 2 N N N N N N CCDC126 high in NP −3.6 0.041768155 −1.4 12991 6 22 18 6 6 6 N N N N N N PIK3CD high in NP −3.9 0.041708831 −1.4 12992 45 116 147 39 28 28 N N N N N N ARHGAP10 high in NP −3.5 0.041669962 −1.4 12993 14 62 32 14 14 14 N N N N N N RILPL2 high in NP −4.0 0.04164746 −1.4 12994 14 119 42 7 2 8 N N N N N N TTC14 high in NP −5.6 0.041640641 −1.4 12995 9 44 47 11 9 9 N P N N P N C2orf18 high in NP −3.3 0.041463348 −1.4 12996 88 261 184 85 47 34 N N N N N N MMD high in NP −2.3 0.041456529 −1.4 12997 21 48 46 18 9 9 N N N N N N DYNC1LI2 high in NP −2.3 0.041420389 −1.4 12998 851 910 821 629 454 254 N N N N N N SGPP1 high in NP −2.3 0.041380839 −1.4 12999 21 87 25 9 9 13 N N N N N N USP14 high in NP −8.0 0.041341289 −1.4 13000 36 337 303 41 38 22 N N N N N N HTATIP2 high in NP −3.3 0.041319468 −1.4 13001 6 33 57 6 6 6 N P N N N N RIOK2 high in NP −3.5 0.041274463 −1.4 13002 9 44 26 9 9 9 N N N N N N GNAQ high in NP −2.4 0.041260825 −1.4 13003 26 25 31 12 12 15 N N N N N N C16orf89 high in NP −7.4 0.041238323 −1.4 13004 5 17 11 5 5 5 N N N N N N PKDCC high in NP −3.3 0.041231504 −1.4 13005 274 85 202 49 27 51 NA NA N N N N PPPDE2 high in NP −6.9 0.041224685 −1.4 13006 1 17 6 1 1 1 NA NA N N N N MSH3 high in NP −2.4 0.041196727 −1.4 13007 16 49 42 16 9 9 N N N N N N MYBPC1 high in NP −7.0 0.041158541 −1.4 13008 6 13 20 6 6 6 N N N N N N SPAST high in NP −2.0 0.041151722 −1.4 13009 18 53 31 14 12 12 N N N N N P LPAR4 high in NP −2.1 0.041131265 −1.4 13010 12 10 16 6 6 6 N N N N N N MIER1 high in NP −2.5 0.041099898 −1.4 13011 18 66 64 20 24 18 N N N N N N KTN1 high in NP −3.2 0.041079441 −1.4 13012 49 145 135 53 44 34 N N N N N N ZNF75D high in NP −2.2 0.041046028 −1.4 13013 10 9 21 4 4 4 N N N N N N FAM45B high in NP −4.8 0.041004432 −1.4 13014 22 6 3 5 1 1 N N N N N N RBM11 high in NP −2.0 0.040853051 −1.4 13015 13 20 14 7 7 7 P N N N N N XPOT high in NP −2.7 0.040831913 −1.4 13016 140 223 156 96 51 25 N N N N N N TRIM69 high in NP −7.8 0.040825094 −1.4 13017 4 12 14 4 4 4 N N N N N N XCL2 high in NP −6.9 0.040810774 −1.4 13018 1 22 6 1 1 1 N N N N N N TCEAL4 high in NP −4.8 0.04079509 −1.4 13019 20 75 108 12 10 13 N N N N N N NOB1 high in NP −2.3 0.04074463 −1.4 13020 57 92 63 28 33 21 N N N N N N TEX10 high in NP −3.3 0.040715309 −1.4 13021 129 323 459 37 80 97 N N N N N N C6orf26 high in NP −3.9 0.040652574 −1.4 13022 9 15 15 3 3 6 N N N N N N LY6E high in NP −2.9 0.040589158 −1.4 13023 1377 640 674 266 445 203 N N N N N N LOC729176 high in NP −7.0 0.04057552 −1.4 13024 1 7 18 1 1 1 N N N N N N PCYOX1L high in NP −7.4 0.040568701 −1.4 13025 3 11 14 3 3 3 N N N N N N PPCS high in NP −6.7 0.040550972 −1.4 13026 3 19 22 3 3 3 N N N N N N TTC28 high in NP −2.3 0.040522332 −1.4 13027 78 84 162 50 51 44 NA NA N N N N SCHIP1 high in NP −3.4 0.04050733 −1.4 13028 114 123 119 35 76 24 N N N N N N TSPYL4 high in NP −2.9 0.040457552 −1.4 13029 17 38 31 11 11 14 N N N N N N NECAB1 high in NP −3.5 0.040396181 −1.4 13030 10 36 38 10 10 10 N N N N N N ANKRD12 high in NP −2.3 0.04033822 −1.4 13031 52 135 112 56 47 51 N N N N N N MGC42105 high in NP −7.1 0.040322537 −1.4 13032 1 8 18 1 1 1 N N N N N N FCN3 high in NP −2.0 0.040257075 −1.4 13033 9 5 6 3 3 3 N N N N N N DPYD high in NP −3.1 0.040250256 −1.4 13034 55 39 72 13 18 26 N N N N N N PPA1 high in NP −4.8 0.040210024 −1.4 13035 71 682 250 49 45 44 N N N N N N ANXA7 high in NP −3.8 0.040102284 −1.4 13036 99 264 226 93 38 20 N N N N N N RPP38 high in NP −6.6 0.040084555 −1.4 13037 2 27 16 2 2 2 N N N N N N ASCC2 high in NP −2.9 0.040054552 −1.4 13038 26 70 33 13 17 13 N N N N N N GOLGA8B high in NP −7.3 0.040047733 −1.4 13039 3 21 9 3 3 3 N N N N N N RND3 high in NP −3.3 0.04002864 −1.4 13040 284 535 641 194 193 208 N N N N P N RPA3 high in NP −6.4 0.039970678 −1.4 13041 3 20 29 3 3 3 N N N N N N TRA2A high in NP −4.1 0.039927719 −1.4 13042 146 478 410 88 71 121 N N N N N N LEPROT high in NP −2.9 0.039902489 −1.4 13043 405 351 255 244 122 93 N N N N N N LOC728758 high in NP −8.8 0.039822707 −1.4 13044 2 11 11 2 2 2 N N N N N N HAT1 high in NP −7.1 0.039783157 −1.4 13045 8 29 27 8 8 8 N N N N N N RDX high in NP −2.6 0.039714286 −1.4 13046 66 198 115 55 37 30 N N N N N N RAB2A high in NP −2.4 0.039707467 −1.4 13047 96 94 60 37 31 17 N N N N N N ACVR1 high in NP −3.2 0.039685646 −1.4 13048 398 272 489 211 112 70 N N N N N N MRPL15 high in NP −23.4 0.039673372 −1.4 13049 3 99 58 6 3 3 N N N N N N OAT high in NP −2.2 0.039666553 −1.4 13050 456 685 675 242 287 256 N N N N N N FAM119B high in NP −2.2 0.039624275 −1.4 13051 173 243 264 89 109 97 P P N N N N CHORDC1 high in NP −3.8 0.039617457 −1.4 13052 5 19 34 5 5 5 N N N N N N CCBL2 high in NP −7.3 0.039610638 −1.4 13053 3 29 9 3 3 3 N N N N P N CLK1 high in NP −2.3 0.039548585 −1.4 13054 543 1104 833 263 264 512 N N N N N N DNAJC7 high in NP −6.3 0.039521309 −1.4 13055 27 194 199 20 19 30 N N N N N N EPB41L2 high in NP −2.7 0.039466076 −1.4 13056 84 219 143 48 25 65 N N N N N N CCND1 high in NP −3.7 0.039442891 −1.4 13057 1140 390 139 121 125 65 N N N N N N SLCO4C1 high in NP −2.2 0.039430617 −1.4 13058 11 8 13 5 5 5 N N N N N N COTL1 high in NP −8.9 0.039414934 −1.4 13059 76 1066 888 41 106 59 N N N N N N TRIAP1 high in NP −6.5 0.039389703 −1.4 13060 5 40 21 5 5 5 N N N N N N ACSS1 high in NP −3.2 0.039332424 −1.4 13061 24 26 58 8 13 11 P N N N N N NLK high in NP −2.4 0.039325605 −1.4 13062 9 33 39 9 9 9 N N N N N N PHF6 high in NP −3.1 0.039318786 −1.4 13063 13 56 52 18 13 13 N N N N P N THUMPD1 high in NP −6.4 0.039286055 −1.4 13064 14 95 75 18 14 14 N N N N N N ZNF300 high in NP −7.7 0.039272417 −1.4 13065 5 22 12 5 5 5 N N N N N N MRPL51 high in NP −18.4 0.039230822 −1.4 13066 2 75 72 5 2 2 N N N N N N C3orf21 high in NP −4.4 0.039196045 −1.4 13067 68 57 20 12 9 9 N N P N N N DOLPP1 high in NP −2.7 0.039052847 −1.4 13068 29 37 41 16 8 3 N N N N N N FAM134C high in NP −2.9 0.03901807 −1.4 13069 266 556 676 208 120 185 N N N N N N GPRASP1 high in NP −3.9 0.039011251 −1.4 13070 13 35 27 13 13 13 N N N N N N APTX high in NP −2.6 0.039004432 −1.4 13071 13 29 38 9 7 7 N N N N N N APPL2 high in NP −5.5 0.038960791 −1.4 13072 14 72 67 12 11 8 N N N N N N GK high in NP −3.9 0.03894238 −1.4 13073 4 31 15 4 4 4 N N N N N N GRINA high in NP −3.1 0.038935561 −1.4 13074 562 566 519 392 147 165 N N N N N N CSRP2BP high in NP −2.2 0.038786908 −1.4 13075 18 12 10 6 6 6 N N N N N N PRRX1 high in NP −2.6 0.038780089 −1.4 13076 2155 1970 1032 1096 488 479 N N P N N N ARAP3 high in NP −3.6 0.038745312 −1.4 13077 16 47 64 16 16 16 N N N N N N FAM133B high in NP −9.0 0.038717354 −1.4 13078 6 19 15 6 6 6 N N N N N N CKS1B high in NP −6.0 0.038632117 −1.4 13079 6 69 53 6 6 9 N N N N N N TRMT11 high in NP −3.9 0.038574838 −1.4 13080 6 23 18 6 6 6 N N N N N N RNF114 high in NP −2.4 0.0385612 −1.4 13081 153 317 215 72 81 112 N N N N N N NSMCE2 high in NP −7.2 0.038535288 −1.4 13082 3 21 27 3 3 3 N N N N N N C1orf123 high in NP −2.6 0.03850733 −1.4 13083 48 41 38 10 4 17 N N N N P N PDCD6 high in NP −8.4 0.038389362 −1.4 13084 8 126 90 10 11 8 N N N N N N CDH4 high in NP −4.4 0.038379134 −1.4 13085 23 9 7 6 6 6 P P N N N N IL1RAP high in NP −3.9 0.038360041 −1.4 13086 16 53 48 16 16 16 N N N N N N RNF6 high in NP −3.9 0.038339584 −1.4 13087 9 33 46 9 9 9 P N N N N N GTF3C6 high in NP −3.7 0.038321855 −1.4 13088 5 20 18 5 5 5 N N N N N N CTBS high in NP −2.2 0.038315036 −1.4 13089 55 54 83 26 19 20 N N N N N N COMMD3 high in NP −9.5 0.03827344 −1.4 13090 2 14 11 2 2 2 N N N N N N PRR3 high in NP −2.9 0.038210706 −1.4 13091 28 50 21 13 7 7 N N N N N N CA12 high in NP −3.5 0.038156154 −1.4 13092 208 199 419 110 104 35 N N N N N N COL5A2 high in NP −3.5 0.038133652 −1.4 13093 1309 160 215 67 53 140 N N N N N N STAT3 high in NP −2.2 0.038121377 −1.4 13094 416 473 442 193 285 221 N N N N N N FIGF high in NP −12.0 0.038103648 −1.4 13095 406 137 19 8 8 21 N P N N N N NFAT5 high in NP −2.2 0.038096829 −1.4 13096 528 545 431 241 308 324 N N N N N N PTTG1IP high in NP −3.4 0.038083873 −1.4 13097 84 232 121 59 43 24 N N N N N N PSMB10 high in NP −6.4 0.038042278 −1.4 13098 9 21 60 5 2 2 N N N N N N FAM129B high in NP −5.4 0.038007501 −1.4 13099 131 569 776 108 156 56 N N N N N N UGP2 high in NP −2.4 0.038000682 −1.4 13100 107 360 123 55 44 36 N N N N N N NUP153 high in NP −3.2 0.037980225 −1.4 13101 255 733 569 126 147 228 N N N N N N KHDRBS1 high in NP −2.8 0.037916127 −1.4 13102 291 577 531 186 183 181 N N N N N N FANCF high in NP −7.2 0.037909308 −1.4 13103 5 23 33 5 5 5 N N N N N N CPNE8 high in NP −3.8 0.037889533 −1.4 13104 11 52 37 11 11 11 N N N N N N ZNF211 high in NP −8.8 0.03787044 −1.4 13105 3 18 11 3 3 3 N N N N N N HSF2 high in NP −2.9 0.037815888 −1.4 13106 6 37 34 6 6 6 N N N N N N PAIP1 high in NP −4.8 0.037787249 −1.4 13107 25 174 95 16 19 11 N N N N N N TMED4 high in NP −2.3 0.037762018 −1.4 13108 71 74 43 26 17 15 N N N N N N TAF7 high in NP −2.8 0.037674736 −1.4 13109 58 90 67 32 25 10 N N N N N N C4orf43 high in NP −7.5 0.037641323 −1.4 13110 4 33 20 4 4 4 N N N N N N C8orf59 high in NP −14.8 0.037598363 −1.4 13111 9 142 150 7 5 2 N N N N N N ADAM9 high in NP −2.2 0.037494033 −1.4 13112 157 185 204 96 89 43 N N N N N N C17orf48 high in NP −8.4 0.037487214 −1.4 13113 3 26 11 3 3 3 N N N N N N TMCO1 high in NP −3.0 0.037473577 −1.4 13114 53 183 97 33 30 17 N N N N P N AP1S2 high in NP −3.0 0.037466758 −1.4 13115 32 75 75 25 12 14 N N N N N N OLFML1 high in NP −9.9 0.037459939 −1.4 13116 434 96 11 6 6 6 N N N N N N CLIC4 high in NP −2.4 0.037393113 −1.4 13117 680 1264 843 519 354 411 N N N N N N OBFC2A high in NP −2.5 0.037371292 −1.4 13118 22 68 61 18 19 21 N N N N N N FAM192A high in NP −4.9 0.037349472 −1.4 13119 16 70 87 12 15 13 NA NA N N N N ELOVL7 high in NP −2.6 0.037272417 −1.4 13120 37 38 23 15 11 11 N N N N N N BHLHE41 high in NP −4.0 0.037248551 −1.4 13121 38 195 91 21 20 21 NA NA N N N N MRPL40 high in NP −2.2 0.037181043 −1.4 13122 10 20 9 4 4 4 N N N N N N GLS high in NP −2.5 0.037157859 −1.4 13123 74 165 155 42 36 67 N N N N N N TMEM131 high in NP −4.1 0.037095124 −1.4 13124 17 74 72 21 17 17 N N N N N N PALLD high in NP −2.7 0.037051483 −1.4 13125 1282 844 676 347 532 257 N N N N N N WSB1 high in NP −4.1 0.037034436 −1.4 13126 10 60 33 10 10 10 N N N N N N SLC9A7 high in NP −8.6 0.037005114 −1.4 13127 7 16 33 7 7 7 N N N N N N VAT1 high in NP −2.8 0.03693897 −1.4 13128 1131 523 1096 435 228 300 N N N N N N C19orf42 high in NP −2.3 0.036926014 −1.4 13129 68 66 74 27 23 10 N N N N N N CREB3L2 high in NP −3.8 0.036833958 −1.4 13130 226 1038 694 251 98 193 N N N N N N CTTN high in NP −2.6 0.036818275 −1.4 13131 628 1211 888 367 455 245 N N N N N N TSPAN1 high in NP −8.8 0.036788953 −1.4 13132 4 14 26 4 4 4 N N N N N N FJX1 high in NP −3.4 0.036782134 −1.4 13133 74 139 65 13 34 27 N 4 N N N N N CES1 high in NP −9.8 0.036775315 −1.4 13134 6 17 19 6 6 6 P N N N N N PPPDE1 high in NP −4.6 0.036728946 −1.4 13135 20 122 97 23 20 17 NA NA N N N N FGB high in NP −9.9 0.036709171 −1.4 13136 1 12 14 1 1 1 P N N N N N POMC high in NP −9.1 0.036677804 −1.4 13137 3 14 21 3 3 3 P P N N N N NGFRAP1 high in NP −2.4 0.036645755 −1.4 13138 17 13 18 6 8 6 N P N N N N TGFBR1 high in NP −2.4 0.036623935 −1.4 13139 117 231 131 61 48 77 N N N N N N GTF2H2D high in NP −8.8 0.036617116 −1.4 13140 1 11 27 1 1 1 NA NA N N N N FAM83A high in NP −7.9 0.036570747 −1.4 13141 5 27 37 5 5 5 N N P N N N SLC16A1 high in NP −3.2 0.036531197 −1.4 13142 28 106 75 29 22 28 N N N N N N INPP1 high in NP −3.1 0.036490965 −1.4 13143 73 29 35 6 18 11 N N N N N N ANKRD30A high in NP −9.9 0.036470508 −1.4 13144 6 17 21 6 6 6 N N N N N N B4GALT3 high in NP −2.3 0.036435049 −1.4 13145 254 382 370 149 76 140 N N N N N N SUPT7L high in NP −2.3 0.036424821 −1.4 13146 67 87 81 37 29 36 N N N N N N EDC3 high in NP −3.1 0.036418002 −1.4 13147 31 61 72 9 22 12 N N N N N N S100P high in NP −9.1 0.036405728 −1.4 13148 2 13 24 2 2 2 N N N N N N CDK5RAP3 high in NP −7.0 0.036398909 −1.4 13149 6 60 70 6 6 9 N N N N N N USP6NL high in NP −2.2 0.036369587 −1.4 13150 26 42 23 15 15 15 N N N N N N C12orf53 high in NP −9.8 0.036325946 −1.4 13151 4 15 20 4 4 4 P N N N N N ABCE1 high in NP −2.2 0.036253665 −1.4 13152 111 306 108 55 46 43 N N N N N N OPN3 high in NP −4.0 0.036246846 −1.4 13153 27 125 87 9 24 14 N N N N N N SFRS4 high in NP −5.9 0.036234572 −1.4 13154 165 1000 739 95 107 156 N N N N N N ZNF117 high in NP −2.7 0.03620866 −1.4 13155 29 34 32 19 13 13 N N N N N N TXNDC5 high in NP −2.7 0.036151381 −1.4 13156 149 558 128 56 65 53 N N N N N N RNF111 high in NP −3.6 0.036144562 −1.4 13157 23 106 105 29 26 29 N N N N N N PA2G4 high in NP −4.3 0.036130924 −1.4 13158 11 68 36 11 11 11 N N N N N N CHD1L high in NP −2.5 0.03611865 −1.4 13159 13 44 24 7 7 7 N N N N N N CSTB high in NP −3.0 0.036106376 −1.4 13160 305 656 822 205 193 123 N N N N N N C10orf78 high in NP −3.3 0.036085919 −1.4 13161 30 18 11 2 2 8 N N N N P N UBE2N high in NP −3.6 0.036019775 −1.4 13162 59 199 123 29 42 36 N N N N N N C1orf128 high in NP −2.3 0.035976816 −1.4 13163 262 676 387 154 111 148 N N N N N N RAB3GAP1 high in NP −2.1 0.035954995 −1.4 13164 168 179 183 71 90 76 N N N N N N OSBPL5 high in NP −2.7 0.03593181 −1.4 13165 192 307 166 113 66 55 N N N N N N PARK7 high in NP −4.9 0.035900443 −1.4 13166 58 104 95 39 16 8 N N N N N N CPNE1 high in NP −2.5 0.035879986 −1.4 13167 2143 1246 1567 890 586 666 N N N N N N DNAJB6 high in NP −3.7 0.035873167 −1.4 13168 600 1501 2032 309 436 558 N N N N N N EMP2 high in NP −2.4 0.035866348 −1.4 13169 454 550 603 264 178 332 N N N N N N CRMP1 high in NP −3.6 0.035830208 −1.4 13170 99 28 26 7 7 15 P P N N N P TBC1D24 high in NP −4.4 0.035815206 −1.4 13171 7 24 33 7 7 7 N N N N N N PRR23A high in NP −3.0 0.035808387 −1.4 13172 276 346 411 67 90 167 NA NA N N N N EIF4A1 high in NP −14.6 0.035781793 −1.4 13173 126 3866 2103 124 147 147 N N N N N N TP53TG1 high in NP −5.4 0.035753836 −1.4 13174 42 13 4 1 8 1 N N N N N N CCDC90B high in NP −7.4 0.035740198 −1.4 13175 32 41 30 21 6 6 N N N N N N MTUS1 high in NP −3.0 0.03569792 −1.4 13176 207 219 439 40 76 150 N N N N N N RAD23B high in NP −2.4 0.035685646 −1.4 13177 264 420 360 153 203 128 N N N N N N HOMER1 high in NP −3.8 0.035678827 −1.4 13178 20 85 68 23 20 24 N N N N N N MGAT2 high in NP −4.2 0.035672008 −1.4 13179 6 56 36 6 6 6 N N N N N N ASB13 high in NP −11.4 0.035645414 −1.4 13180 8 21 20 8 8 8 N N N N P N LOXL1 high in NP −3.0 0.035622912 −1.4 13181 766 252 148 74 56 77 N N N N N N GSDMD high in NP −2.5 0.035572451 −1.4 13182 95 89 72 31 33 20 N N N N N N PRMT5 high in NP −8.6 0.035473577 −1.5 13183 46 397 459 50 28 23 N N N N N N NCRNA00095 high in NP −4.3 0.035431981 −1.5 13184 138 507 509 107 80 102 N N N N N N C12orf75 high in NP −5.0 0.035419707 −1.5 13185 6 84 21 6 6 6 NA NA N N N N IPO8 high in NP −4.7 0.035397204 −1.5 13186 13 62 29 13 13 13 N N N N N N CES8 high in NP −8.4 0.035386976 −1.5 13187 6 29 43 6 6 6 NA NA N N N N PPP1R2P3 high in NP −10.2 0.035369928 −1.5 13188 1 13 19 1 1 1 N P N N N N CBX6 high in NP −2.6 0.035363109 −1.5 13189 35 75 56 24 14 11 N N N N N N RWDD1 high in NP −2.4 0.035340607 −1.5 13190 378 474 291 133 177 105 N N N N N N CAMK2D high in NP −2.7 0.03530583 −1.5 13191 198 289 291 123 51 133 N N N N N N TTC7B high in NP −3.5 0.035292192 −1.5 13192 17 52 42 10 13 10 N N N N N N HTRA2 high in NP −2.3 0.035281964 −1.5 13193 66 120 88 38 28 34 N P N N N N SLC26A3 high in NP −10.1 0.035275145 −1.5 13194 2 15 22 2 2 2 N N N N N N SH3YL1 high in NP −7.5 0.035262871 −1.5 13195 6 63 74 6 8 6 N N N N N N RSAD2 high in NP −3.1 0.035236959 −1.5 13196 46 134 87 24 20 26 N N N N N N RAB6C high in NP −44.0 0.035224685 −1.5 13197 1 183 78 3 1 1 N P N N N N PSMB1 high in NP −2.8 0.035206955 −1.5 13198 136 1494 170 71 49 43 N N N N N N NPDC1 high in NP −2.9 0.035200136 −1.5 13199 448 167 292 81 84 83 N N N N N N ZNF148 high in NP −2.2 0.035193317 −1.5 13200 61 87 61 34 34 29 N N N N N N C14orf132 high in NP −2.3 0.035146267 −1.5 13201 53 43 51 20 20 20 N N N N N N MYOF high in NP −2.0 0.035139448 −1.5 13202 37 57 49 30 29 26 NA NA N N N N LOC96610 high in NP −4.6 0.03512581 −1.5 13203 6 30 23 6 6 6 NA NA N N N N RBM7 high in NP −3.1 0.035118991 −1.5 13204 90 118 166 32 17 56 N N N N N N AGAP1 high in NP −2.4 0.035083532 −1.5 13205 104 127 80 47 38 38 N N N N N N MRPL35 high in NP −4.7 0.034998295 −1.5 13206 6 20 41 6 6 6 N N N N N N HMGB1 high in NP −6.3 0.034991476 −1.5 13207 23 140 90 21 22 17 N N N N N N SRGN high in NP −5.3 0.034984657 −1.5 13208 144 1955 132 69 23 52 N N N N N N KEAP1 high in NP −9.3 0.034965564 −1.5 13209 21 211 315 23 24 18 N N N N N N DSTN high in NP −6.6 0.034872145 −1.5 13210 104 599 386 66 98 53 N N N N N N COX6A1 high in NP −21.3 0.034828503 −1.5 13211 8 398 218 12 8 11 N N N N N N TMEM35 high in NP −2.5 0.034801909 −1.5 13212 10 11 7 4 4 4 N N N N N N NBL1 high in NP −3.6 0.034754177 −1.5 13213 113 388 146 101 30 34 N N N N N N WDR82 high in NP −2.8 0.034698943 −1.5 13214 177 484 317 116 112 126 N N N N P N MAGED1 high in NP −8.6 0.034678486 −1.5 13215 6 72 25 6 6 6 P P N N N N ARPC4 high in NP −2.8 0.034655984 −1.5 13216 1102 705 580 450 263 94 N N N N N N ARRDC3 high in NP −3.5 0.034634163 −1.5 13217 475 1104 1574 220 290 524 N N N N N N DEF6 high in NP −4.2 0.034612342 −1.5 13218 21 59 50 7 12 10 N N N N N N RASA1 high in NP −2.6 0.034578929 −1.5 13219 79 54 84 33 27 24 N N N N N N SHFM1 high in NP −28.2 0.034538698 −1.5 13220 2 224 94 2 4 2 N P N N N N RAB37 high in NP −2.3 0.03452506 −1.5 13221 9 7 5 3 3 3 P P N N N N H6PD high in NP −2.6 0.034511422 −1.5 13222 146 176 92 72 39 30 N N N N N N FAM101B high in NP −2.7 0.034504603 −1.5 13223 99 173 67 42 32 21 N N N N N N STX18 high in NP −4.8 0.03447119 −1.5 13224 8 25 32 8 8 8 N N N N N N ZNF137 high in NP −2.5 0.034446642 −1.5 13225 9 12 6 3 3 3 N N N N N N MRPL50 high in NP −10.5 0.034439823 −1.5 13226 3 28 14 3 3 3 N N N N N N RIN2 high in NP −3.5 0.034426185 −1.5 13227 15 43 54 15 15 15 N N N N N N PRKAA1 high in NP −2.4 0.034419366 −1.5 13228 21 39 49 17 15 15 N N N N N N TSPO high in NP −8.6 0.034396863 −1.5 13229 7 162 123 7 7 13 N N N N N N LOC100216001 high in NP −11.6 0.034373679 −1.5 13230 3 23 16 3 3 3 N N N N N N EPHX2 high in NP −5.6 0.034342994 −1.5 13231 110 26 50 8 18 19 N N N N N N CCL28 high in NP −8.8 0.034313672 −1.5 13232 5 29 52 5 5 5 N N N N N N DIAPH1 high in NP −3.4 0.034300034 −1.5 13233 489 620 576 187 377 132 N N N N N N TSPAN4 high in NP −3.3 0.034280941 −1.5 13234 243 143 143 60 16 64 N N N N N N CLU high in NP −4.6 0.034265257 −1.5 13235 118 586 105 23 71 41 N N N N N N BBS10 high in NP −2.7 0.034247528 −1.5 13236 30 37 45 16 13 11 N N N N N N TIFA high in NP −2.2 0.034240709 −1.5 13237 15 42 26 9 9 9 N N N N N N C1orf210 high in NP −4.8 0.03423389 −1.5 13238 8 24 34 8 8 8 N N N N N N ALDH7A1 high in NP −3.3 0.034223662 −1.5 13239 77 74 41 25 27 22 N N N N N N B4GALT4 high in NP −4.9 0.03419775 −1.5 13240 6 47 22 6 6 6 N N N N N N C11orf1 high in NP −11.6 0.034170474 −1.5 13241 3 17 21 3 3 3 N N N N N N HELLS high in NP −4.5 0.034147971 −1.5 13242 8 29 29 8 8 8 N N N N N N C7orf30 high in NP −2.8 0.034117286 −1.5 13243 70 93 110 34 24 10 N N N N N N MYH10 high in NP −2.7 0.034076372 −1.5 13244 72 42 59 26 30 23 N N N N N N TRIM4 high in NP −2.5 0.034064098 −1.5 13245 25 56 55 13 16 19 N N N N N N TUBB high in NP −3.6 0.034049096 −1.5 13246 8275 2815 3566 1963 1018 916 N N N N N N PUF60 high in NP −2.2 0.034015684 −1.5 13247 367 358 433 191 178 119 N N N N N N WBP5 high in NP −8.5 0.033961132 −1.5 13248 56 249 334 31 35 33 N N N N N N ABT1 high in NP −2.9 0.033794749 −1.5 13249 75 138 170 51 39 14 N P N N N N PLEKHF2 high in NP −4.2 0.03376611 −1.5 13250 28 71 116 19 17 7 N N N N N N MAGEH1 high in NP −3.5 0.033759291 −1.5 13251 50 77 63 26 3 14 N N N N N N MT1F high in NP −5.1 0.033684964 −1.5 13252 7 233 4 1 1 1 N N N N N N LIMA1 high in NP −3.8 0.033664507 −1.5 13253 65 221 59 21 40 21 N N N N N N FKBP7 high in NP −3.5 0.033616093 −1.5 13254 237 107 84 20 20 59 N N N N N N SMARCD1 high in NP −3.5 0.033576543 −1.5 13255 16 63 77 9 17 9 N N N N N N GLUD2 high in NP −11.9 0.033547903 −1.5 13256 2 25 15 2 2 2 N N N N N N DST high in NP −3.4 0.03347835 −1.5 13257 157 451 372 138 201 153 N N N N N N PKN1 high in NP −3.3 0.033464712 −1.5 13258 243 121 187 85 20 51 N N N N N N TWSG1 high in NP −5.4 0.033449028 −1.5 13259 31 220 112 16 23 21 N N N N N N CNOT10 high in NP −3.6 0.033442209 −1.5 13260 14 27 28 10 8 8 N N N N N N NAA50 high in NP −8.4 0.033428571 −1.5 13261 63 540 450 53 38 64 NA NA N N N N HPS3 high in NP −5.0 0.033414934 −1.5 13262 10 31 25 10 10 10 N N N N N N OBFC1 high in NP −2.6 0.033401296 −1.5 13263 63 76 92 40 25 22 N N N N N N CLEC3B high in NP −4.8 0.033394477 −1.5 13264 751 796 2609 120 323 473 N N N N N N ROBO1 high in NP −3.1 0.033387658 −1.5 13265 22 76 48 16 16 19 N N N N N N EFEMP2 high in NP −4.0 0.03337061 −1.5 13266 1118 236 400 187 71 84 N N N N N N PHKG2 high in NP −10.1 0.033316741 −1.5 13267 7 46 35 7 7 7 N N N N N N SHMT2 high in NP −6.7 0.033309922 −1.5 13268 31 310 171 37 20 16 N N N N N N C16orf63 high in NP −7.9 0.033297647 −1.5 13269 6 71 77 9 6 6 N N N N N N ATF6 high in NP −5.0 0.033271735 −1.5 13270 9 51 38 9 9 9 N N N N N N SLBP high in NP −8.2 0.033264916 −1.5 13271 25 228 189 13 16 22 N N N N N N TMEM158 high in NP −2.2 0.033237641 −1.5 13272 164 182 198 80 42 76 N N N N N N NRAS high in NP −3.3 0.033192636 −1.5 13273 285 174 136 83 74 25 N N N N N N LDLRAD3 high in NP −3.2 0.033164678 −1.5 13274 117 364 71 36 38 23 N N N N N N DNALI1 high in NP −5.7 0.033157859 −1.5 13275 32 20 38 15 6 6 N N N N N N YEATS4 high in NP −11.2 0.033109444 −1.5 13276 3 38 33 3 3 3 N N N N N P NUCB1 high in NP −3.1 0.033096488 −1.5 13277 371 249 122 66 53 64 N N N N N N MPV17 high in NP −3.1 0.033089669 −1.5 13278 41 60 100 21 11 14 N N N N N N BAX high in NP −7.8 0.033076713 −1.5 13279 17 86 101 6 13 9 N N N N N N FSCN1 high in NP −3.6 0.033037163 −1.5 13280 870 275 369 70 111 197 N N N N N N GCLM high in NP −4.2 0.033024889 −1.5 13281 190 479 710 110 147 111 N N N N P N C13orf37 high in NP −4.8 0.03301807 −1.5 13282 8 29 29 8 8 8 N N N N N N NEK6 high in NP −2.3 0.033011251 −1.5 13283 15 25 27 9 9 9 N N N N N N SYNGR2 high in NP −2.7 0.032988749 −1.5 13284 377 374 243 154 128 44 N N N N N N RUSC2 high in NP −3.0 0.032975111 −1.5 13285 71 172 175 49 34 49 N N N N N N TIMM10 high in NP −2.7 0.032968292 −1.5 13286 126 146 220 43 69 26 N N N N N N SLC7A6OS high in NP −12.7 0.03295329 −1.5 13287 4 28 19 4 4 4 N N N N N N ZFR high in NP −4.2 0.032867371 −1.5 13288 85 215 240 62 43 43 N N N N N N SART3 high in NP −4.3 0.032830549 −1.5 13289 29 166 162 22 26 30 N N N N P N MAGI1 high in NP −2.7 0.032803955 −1.5 13290 99 58 61 32 33 24 N N N N N N KRR1 high in NP −3.2 0.032790317 −1.5 13291 65 115 138 30 37 34 N N N N N N PRINS high in NP −3.0 0.032773952 −1.5 13292 49 37 64 13 21 14 N N N N N N C11orf2 high in NP −3.8 0.032711899 −1.5 13293 7 57 71 7 7 10 N N N N N N ZMYM2 high in NP −2.2 0.032698261 −1.5 13294 21 47 56 19 15 15 N N N N N N FBXO28 high in NP −2.5 0.03267985 −1.5 13295 201 202 137 92 81 52 N N N N N N LETMD1 high in NP −5.3 0.032673031 −1.5 13296 11 33 33 11 11 11 N N N N N N PSMD10 high in NP −4.9 0.032666212 −1.5 13297 5 27 25 5 5 5 N N N N N N CNIH high in NP −3.2 0.032659393 −1.5 13298 24 65 44 16 12 15 N N N N N N COQ2 high in NP −4.5 0.032652574 −1.5 13299 23 14 4 7 2 2 N N N N N N RADIL high in NP −3.4 0.032645755 −1.5 13300 80 41 55 19 8 18 N N N N N N CSTA high in NP −14.4 0.032632117 −1.5 13301 2 22 18 2 2 2 N N N N N N SERPINA3 high in NP −9.7 0.032613024 −1.5 13302 88 1601 2333 30 235 38 P N N N N N B9D1 high in NP −5.7 0.032606205 −1.5 13303 9 18 21 6 3 3 N N N N N N MRPL13 high in NP −12.3 0.032593249 −1.5 13304 4 41 18 4 4 4 N N N N N N KLF3 high in NP −2.4 0.032511422 −1.5 13305 226 273 277 151 61 112 N N N N N N API5 high in NP −7.8 0.032487555 −1.5 13306 12 97 147 12 12 18 N N N N N N SNX17 high in NP −2.8 0.032424821 −1.5 13307 21 81 74 22 10 10 N N N N N N C3orf17 high in NP −2.2 0.032403 −1.5 13308 60 118 83 41 35 32 N N N N N N ZNF770 high in NP −2.6 0.032396181 −1.5 13309 127 169 255 71 59 82 N N N N N N AHR high in NP −3.1 0.032375043 −1.5 13310 343 852 662 267 225 240 N N N N N N RAB33B high in NP −2.2 0.032368224 −1.5 13311 34 46 57 20 21 21 N N N N P N PLEKHA9 high in NP −14.3 0.03235254 −1.5 13312 4 23 25 4 4 4 N N N N N N RAB23 high in NP −12.0 0.032336856 −1.5 13313 4 42 39 4 4 4 N N N N N N LRRC8A high in NP −2.4 0.032323219 −1.5 13314 1195 1025 1232 443 497 669 N N N N N N ACTB high in NP −2.7 0.032309581 −1.5 13315 148 267 186 71 114 38 N N N N N N BOLA1 high in NP −2.5 0.032302762 −1.5 13316 9 11 6 3 3 3 N N N N N N LGALS3 high in NP −14.4 0.032295943 −1.5 13317 33 786 526 29 28 36 N N N N N N MED21 high in NP −5.6 0.03227344 −1.5 13318 9 46 52 9 9 9 N N N N N N RPS19 high in NP −13.9 0.032232526 −1.5 13319 202 5679 2849 150 203 179 N N N N N N AGK high in NP −14.3 0.032204569 −1.5 13320 6 24 29 6 6 6 N N N N N N UXT high in NP −3.2 0.032190931 −1.5 13321 163 426 324 114 55 75 N N N N N N PMVK high in NP −7.4 0.032158882 −1.5 13322 13 54 35 7 10 7 N N N N N N NFIA high in NP −3.9 0.032120696 −1.5 13323 1042 358 244 256 70 134 N N N N N N C1orf103 high in NP −3.6 0.032098875 −1.5 13324 13 47 13 6 6 6 N P N N N N HOOK2 high in NP −5.7 0.032071599 −1.5 13325 11 47 48 11 11 11 N N N N N N RHOT1 high in NP −2.9 0.032045687 −1.5 13326 52 43 47 22 12 12 N N N N N N CCNT1 high in NP −2.6 0.032038868 −1.5 13327 24 45 21 8 11 8 N N N N P N LOC388796 high in NP −8.5 0.032018411 −1.5 13328 44 545 399 18 50 24 N N N N N N ACSL3 high in NP −6.2 0.032003409 −1.5 13329 51 273 268 27 47 37 N N N N N N PLEKHH2 high in NP −4.8 0.031980907 −1.5 13330 53 353 247 43 42 41 N N N N N N ZNF71 high in NP −3.1 0.031974088 −1.5 13331 29 18 16 10 6 6 P N N N N N IFNGR1 high in NP −2.9 0.031967269 −1.5 13332 47 120 102 39 26 22 N N N N N N TMEM144 high in NP −2.9 0.031911354 −1.5 13333 13 12 23 7 7 7 N N N N N N SEC24A high in NP −3.3 0.0318418 −1.5 13334 146 441 340 71 101 114 N N N N N N SH3BP5 high in NP −3.9 0.031794749 −1.5 13335 105 329 248 66 47 66 N N N N N N FSTL1 high in NP −2.9 0.031784521 −1.5 13336 15169 5551 5318 2198 1792 3168 N N N N N N FAM162A high in NP −16.9 0.031756563 −1.5 13337 11 151 115 5 8 8 N N N N N N N4BP2L1 high in NP −3.0 0.031723832 −1.5 13338 48 26 42 15 11 14 N N N N N N JAK1 high in NP −3.5 0.031717013 −1.5 13339 134 349 190 83 52 108 N N N N N N STAT1 high in NP −3.0 0.03170133 −1.5 13340 212 190 215 121 62 53 N N N N P N PRKACB high in NP −2.6 0.031625639 −1.5 13341 123 35 44 15 11 11 N N N N N N DUSP5 high in NP −2.6 0.031605182 −1.5 13342 595 723 563 227 239 355 N N N N P N COX5A high in NP −6.3 0.031556768 −1.5 13343 43 211 281 20 31 25 N N N N N N C11orf24 high in NP −3.7 0.031522673 −1.5 13344 52 152 68 34 16 9 N N N N N N EFNA4 high in NP −14.3 0.031505626 −1.5 13345 5 23 33 5 5 5 N N N N N P TMEM130 high in NP −5.6 0.031493352 −1.5 13346 256 27 20 7 7 15 N N N N N N LIMCH1 high in NP −3.7 0.031428571 −1.5 13347 59 96 111 24 29 48 N N P N N N SFPQ high in NP −3.3 0.031382203 −1.5 13348 359 775 858 230 289 222 N N N N N N SLC9A3R2 high in NP −2.9 0.031354245 −1.5 13349 67 40 35 14 16 5 N N N N N N LPHN3 high in NP −4.6 0.031347426 −1.5 13350 173 25 12 8 8 8 N N N N N N CKAP4 high in NP −3.7 0.031340607 −1.5 13351 2102 1398 1743 1022 408 350 N N N N N N CYP7B1 high in NP −15.1 0.031302421 −1.5 13352 3 32 20 3 3 3 N N N N N N MBOAT1 high in NP −3.6 0.031275145 −1.5 13353 17 113 82 17 19 20 N N N N N N SPCS1 high in NP −2.7 0.031268326 −1.5 13354 673 458 441 259 169 69 N N N N N N LMNA high in NP −3.3 0.031261507 −1.5 13355 6193 4679 5860 1655 1468 3323 N N N N N N LOC100233209 high in NP −2.7 0.031205592 −1.5 13356 180 381 320 111 74 109 NA NA N N N N ECHDC3 high in NP −11.7 0.031198773 −1.5 13357 6 75 39 6 6 6 N N N N N N CAPNS1 high in NP −2.4 0.031148312 −1.5 13358 705 547 550 243 296 135 N N N N N N PSPC1 high in NP −2.8 0.031117627 −1.5 13359 22 53 37 9 15 9 N N N N N N DERL2 high in NP −16.5 0.03109717 −1.5 13360 5 195 166 7 5 8 N N N N N N GSTP1 high in NP −2.3 0.031081487 −1.5 13361 1608 1681 1873 816 683 282 N N N N N N SLCO4A1 high in NP −2.9 0.031015343 −1.5 13362 46 100 115 22 16 29 N N N N N N ZSWIM4 high in NP −6.8 0.031001705 −1.5 13363 13 149 157 16 21 13 N N N N N N DEPDC6 high in NP −2.7 0.030979884 −1.5 13364 17 18 28 10 10 10 N N N N N N ERRFI1 high in NP −7.2 0.030973065 −1.5 13365 291 3460 2684 168 132 483 N N N N N N PDGFB high in NP −2.3 0.030951926 −1.5 13366 49 26 25 13 10 10 N P N N N N RYK high in NP −2.3 0.030938288 −1.5 13367 227 135 161 74 71 52 N N N N N N RBBP5 high in NP −5.9 0.030916468 −1.5 13368 9 46 30 9 9 9 N N N N N N SUDS3 high in NP −2.4 0.030909649 −1.5 13369 61 85 66 29 36 18 N N N N N N ARL6IP4 high in NP −2.7 0.030880327 −1.5 13370 187 404 367 145 73 73 N N N N N N TMEM51 high in NP −3.1 0.030873508 −1.5 13371 86 235 178 28 44 53 N N N N N N POLR1D high in NP −4.5 0.030845551 −1.5 13372 79 518 257 53 47 41 N N N N N N C17orf81 high in NP −2.8 0.030816229 −1.5 13373 37 68 65 18 20 17 N N N N N N MOBKL3 high in NP −6.2 0.030774633 −1.5 13374 7 49 44 7 7 7 N N N N N N GNPNAT1 high in NP −4.1 0.030748721 −1.5 13375 20 153 51 13 16 13 N N N N N N SLC25A28 high in NP −2.9 0.030707126 −1.5 13376 74 278 139 47 38 38 N N N N N N SUMO3 high in NP −2.8 0.030636891 −1.5 13377 440 357 300 201 123 80 N N N N N N ENSA high in NP −2.7 0.030614388 −1.5 13378 85 122 166 67 36 40 N N N N N N SRP68 high in NP −5.4 0.030607569 −1.5 13379 27 160 149 28 9 13 P N N N N N SGCE high in NP −3.2 0.030565292 −1.5 13380 212 332 108 35 35 88 N N N N N N SSBP1 high in NP −8.2 0.030524378 −1.5 13381 11 60 40 5 5 8 N N N N N N PPP1R15B high in NP −2.8 0.03051074 −1.5 13382 2506 2264 1780 695 676 1261 N N N N N N PSMC4 high in NP −8.7 0.030497102 −1.5 13383 97 904 840 83 87 44 N N N N N N DCP1A high in NP −2.3 0.030460961 −1.5 13384 102 135 96 57 46 50 N N N N N N STK32B high in NP −2.7 0.030385953 −1.5 13385 16 29 32 9 9 9 N N N N N N PLN high in NP −3.1 0.030372315 −1.5 13386 9 18 8 3 3 3 N N N N N N SRPK1 high in NP −3.4 0.030365496 −1.5 13387 83 173 241 46 52 26 N N N N N N BGN high in NP −4.6 0.030351858 −1.5 13388 2295 3136 344 107 70 601 N N N N N N MAL2 high in NP −3.5 0.030285032 −1.5 13389 9 53 96 9 9 9 P P N N N N MSTO1 high in NP −2.6 0.030232526 −1.5 13390 8 8 2 2 2 2 N N N N N N EIF3E high in NP −2.8 0.030225707 −1.5 13391 56 94 105 23 31 29 N N N N P N NEK5 high in NP −3.1 0.030196386 −1.5 13392 60 260 81 25 20 15 N N N N N N E2F5 high in NP −16.7 0.030182748 −1.5 13393 6 29 39 6 6 6 N N N N N N SSR4 high in NP −2.8 0.030152063 −1.5 13394 408 775 461 265 145 113 N N N N N N AXL high in NP −2.4 0.030145244 −1.5 13395 1940 2302 2209 927 616 1143 N N N N N N GYG1 high in NP −4.1 0.030138425 −1.5 13396 253 286 84 55 47 23 N N N N N N NDUFA11 high in NP −3.3 0.030084555 −1.5 13397 412 444 278 171 114 53 N N N N P N EHD4 high in NP −2.9 0.029987044 −1.5 13398 27 71 45 17 17 14 N N N N P N WASL high in NP −3.8 0.029937266 −1.5 13399 64 230 159 66 26 35 N N N N N N KRT6B high in NP −14.1 0.029890215 −1.5 13400 120 1046 469 34 198 21 N N N N N N TAF6 high in NP −5.9 0.029862257 −1.5 13401 34 56 50 25 8 8 N N N N N N LIMS1 high in NP −14.1 0.029855438 −1.5 13402 3 62 40 3 3 3 N N N N N N ATP1A1 high in NP −2.4 0.029848619 −1.5 13403 1318 1974 2693 774 681 767 N N N N N N S100A4 high in NP −8.1 0.029813161 −1.5 13404 18 476 92 10 9 9 N N N N N N TXNIP high in NP −6.1 0.029767474 −1.5 13405 109 609 489 86 44 91 N N N N N N CAV1 high in NP −3.9 0.029760655 −1.5 13406 2594 2548 859 712 707 240 N N N N N N CBLC high in NP −6.7 0.029747017 −1.5 13407 6 32 74 6 6 6 N N N N N P ARMCX1 high in NP −3.6 0.029674054 −1.5 13408 89 153 243 33 26 52 N N N N N N RPS15A high in NP −3.0 0.029625639 −1.5 13409 837 1379 1512 230 409 531 N N N N N N SLC35B3 high in NP −3.8 0.029588817 −1.5 13410 41 18 39 11 5 8 N N N N N N C1orf86 high in NP −2.4 0.029545176 −1.5 13411 98 114 211 37 34 36 N N N N N N C1orf77 high in NP −6.8 0.029538357 −1.5 13412 16 96 104 9 5 10 N N N N N N ZNF165 high in NP −2.9 0.029522673 −1.5 13413 12 13 29 6 6 6 N N N N N N RGS5 high in NP −6.2 0.029457211 −1.5 13414 3925 1963 543 619 235 278 N N N N N N COMMD10 high in NP −2.6 0.029419025 −1.5 13415 9 4 8 3 3 3 N N N N N N SDHAF2 high in NP −2.7 0.029393113 −1.5 13416 110 206 222 77 49 35 NA NA N N N N MRPS30 high in NP −3.3 0.029363109 −1.5 13417 81 96 86 20 36 18 N N N N N N EHD2 high in NP −3.8 0.02935629 −1.5 13418 7734 2327 1103 998 589 329 N N N N N N GJC2 high in NP −2.5 0.029342653 −1.5 13419 43 30 50 15 14 15 N N N N N N SUGT1 high in NP −5.4 0.029301057 −1.5 13420 23 109 73 13 14 9 N N N N N N CYC1 high in NP −3.7 0.029271054 −1.5 13421 14 69 71 8 13 8 N N N N N N CASP7 high in NP −3.8 0.029156495 −1.5 13422 34 85 56 29 13 13 N N N N N N AHNAK high in NP −2.4 0.029133992 −1.5 13423 218 236 282 112 158 122 N N N N N N GTF3C1 high in NP −2.4 0.029079441 −1.5 13424 204 195 271 99 106 70 N N N N N N SPINT1 high in NP −5.7 0.02904671 −1.5 13425 75 398 507 38 77 13 N N N N N N INPP5E high in NP −2.6 0.029031026 −1.5 13426 24 42 32 10 14 8 N N N N N N GNG5 high in NP −9.3 0.028986021 −1.5 13427 50 366 435 37 24 19 N N N N N N GGT5 high in NP −3.8 0.028911013 −1.5 13428 1542 337 163 71 53 77 N N N N N N C9orf21 high in NP −3.3 0.028904194 −1.5 13429 433 520 232 133 106 112 N N N N N N BLMH high in NP −2.8 0.02889192 −1.5 13430 107 157 66 38 20 34 N N N N N N PPP2R1A high in NP −3.1 0.028833958 −1.5 13431 1087 724 748 377 369 183 N N N N N N MAP1B high in NP −2.5 0.028813502 −1.5 13432 1050 1094 1416 742 511 330 N N N N N N UBE2Q2 high in NP −6.6 0.028792363 −1.5 13433 6 110 60 6 6 6 N N N N N P POMP high in NP −3.0 0.028785544 −1.5 13434 620 962 1226 417 301 135 N N N N N N FHL1 high in NP −3.6 0.028778725 −1.5 13435 203 352 102 59 26 62 N N N N N N HSPA5 high in NP −4.1 0.028763041 −1.5 13436 1055 4599 5027 1252 423 352 N N N N N N C7orf23 high in NP −17.4 0.028756222 −1.5 13437 6 57 62 6 6 6 N N N N N N DUSP4 high in NP −4.5 0.028749403 −1.5 13438 33 153 119 16 33 19 P P N N N N TIGD3 high in NP −3.0 0.028742584 −1.5 13439 10 14 8 4 4 4 N P N N N N TFF1 high in NP −14.7 0.028722128 −1.5 13440 55 59 101 6 42 3 P P N N N N SIK1 high in NP −2.6 0.028701671 −1.5 13441 2391 3190 3111 1005 1266 1641 NA NA N N N N MRPL9 high in NP −4.0 0.028608251 −1.5 13442 9 40 11 3 3 3 N N N N N N HBA1 high in NP −65.8 0.02852506 −1.5 13443 28 14210 1814 20 13 19 P P N N N N LOC100190939 high in NP −2.3 0.028500511 −1.5 13444 165 168 209 63 81 59 N N N N N N PM20D2 high in NP −3.0 0.028493692 −1.5 13445 29 62 75 18 14 17 N N N N N N ARIH2 high in NP −2.5 0.028467099 −1.5 13446 217 367 320 132 153 96 N N N N N N HTRA1 high in NP −4.2 0.02846028 −1.5 13447 62 469 52 17 14 22 N N N N N N RPLP1 high in NP −18.6 0.028453461 −1.5 13448 97 3274 1202 62 55 82 N N N N N N DCAF12 high in NP −3.8 0.028411865 −1.5 13449 70 215 145 26 33 50 NA NA N N N N NUP133 high in NP −3.5 0.028405046 −1.5 13450 20 48 53 16 13 13 N N N N N N C1orf198 high in NP −2.6 0.028391408 −1.5 13451 2204 1219 1098 513 476 707 N N N N N N HIATL1 high in NP −2.7 0.028301398 −1.5 13452 142 371 238 82 59 83 N N N N N N RGS2 high in NP −3.8 0.028289124 −1.5 13453 59 62 54 9 14 28 N N N N N N PDGFC high in NP −2.8 0.0282373 −1.5 13454 18 36 37 9 7 10 N N N N N P ARAP1 high in NP −2.5 0.028230481 −1.5 13455 49 94 67 27 22 28 N N N N N N MRFAP1 high in NP −13.5 0.028195704 −1.5 13456 12 224 106 14 12 12 N N N N N N MRPL36 high in NP −21.1 0.028188885 −1.5 13457 5 52 31 5 5 5 N N N N N N SCNN1B high in NP −3.4 0.028182066 −1.6 13458 13 13 23 6 6 6 P P N N N N IL33 high in NP −4.4 0.028175247 −1.6 13459 62 137 40 24 9 9 N N N N N N KLHL13 high in NP −3.6 0.028147971 −1.6 13460 16 61 28 9 9 9 N N N N N N TC2N high in NP −3.9 0.02811524 −1.6 13461 19 62 85 13 18 13 N N N N P N EEF1E1 high in NP −18.6 0.028108421 −1.6 13462 2 58 65 2 2 2 N P N N N N EMP1 high in NP −3.2 0.028063416 −1.6 13463 2727 5901 5107 823 1578 1842 N N N N N N RC3H1 high in NP −3.3 0.028043641 −1.6 13464 119 311 308 60 73 100 N N N N N N FAM107B high in NP −2.5 0.028036822 −1.6 13465 247 408 267 96 141 120 N N N N N N ZNF706 high in NP −2.6 0.028023184 −1.6 13466 186 316 317 84 89 108 N N N N N N SRPRB high in NP −10.6 0.028010228 −1.6 13467 41 429 249 30 21 20 N P N N N N SNHG6 high in NP −4.8 0.027996591 −1.6 13468 196 780 748 84 101 144 N N N N N N EREG high in NP −4.2 0.027984316 −1.6 13469 17 105 75 14 13 13 P P N N N N SURF1 high in NP −18.3 0.027977497 −1.6 13470 2 69 55 2 2 2 N N N N N N NAAA high in NP −4.0 0.027957041 −1.6 13471 31 36 24 15 9 9 N N N N N N C3orf31 high in NP −2.7 0.027916809 −1.6 13472 11 6 9 5 5 5 N N N N N N ARL8B high in NP −4.8 0.027869758 −1.6 13473 188 544 672 106 127 139 N N N N N N RBM9 high in NP −3.0 0.027862939 −1.6 13474 889 610 582 377 201 331 N N N N N N PPP1R2 high in NP −3.3 0.027833617 −1.6 13475 50 113 92 25 26 15 N N N N N N C6orf108 high in NP −3.6 0.027794068 −1.6 13476 96 39 73 21 15 6 N N N N N N ZWINT high in NP −3.0 0.027755199 −1.6 13477 9 9 11 3 3 3 N N N N N N CMPK2 high in NP −3.3 0.027728606 −1.6 13478 47 48 17 13 8 10 N N N N N N FAM198B high in NP −2.6 0.027721787 −1.6 13479 249 405 186 67 87 99 NA NA N N N N C20orf30 high in NP −3.0 0.027686328 −1.6 13480 606 398 396 239 116 85 N N N N N N GUK1 high in NP −2.4 0.027668599 −1.6 13481 328 512 388 144 139 169 N N N N N N UROD high in NP −4.2 0.027649506 −1.6 13482 52 74 84 33 13 16 N N N N N N SCAMP5 high in NP −4.6 0.027628367 −1.6 13483 57 17 25 15 10 10 N P N N N N FLNC high in NP −3.2 0.027621548 −1.6 13484 101 149 258 29 37 78 N N N N N N CCDC83 high in NP −8.3 0.027579952 −1.6 13485 9 33 26 2 5 2 N N N N N N SMARCD2 high in NP −2.8 0.02755745 −1.6 13486 112 95 145 46 21 42 N N N N N N UBTD2 high in NP −5.2 0.027544494 −1.6 13487 141 590 554 78 61 120 N N N N N N SIKE1 high in NP −2.9 0.027537675 −1.6 13488 21 44 47 14 12 9 NA NA N N N N SETD3 high in NP −3.0 0.027530856 −1.6 13489 66 54 35 17 19 12 N N N N N N TMEM205 high in NP −3.6 0.027524037 −1.6 13490 58 224 108 35 22 14 N N N N N N AQP1 high in NP −5.1 0.027508353 −1.6 13491 200 599 79 30 57 39 N N N N N N TNFRSF14 high in NP −2.5 0.027485851 −1.6 13492 161 67 84 32 23 31 N P N N N N ZNF217 high in NP −7.4 0.027438118 −1.6 13493 71 389 428 48 30 51 N N N N N N DNTTIP1 high in NP −20.6 0.027337197 −1.6 13494 5 71 72 5 5 5 N N N N N N COL21A1 high in NP −2.2 0.027324923 −1.6 13495 20 23 26 9 9 9 N N N N N N LIF high in NP −5.0 0.027295602 −1.6 13496 479 2636 1933 423 453 184 N N N N N N PTGDS high in NP −5.5 0.027268326 −1.6 13497 93 487 337 47 24 76 N N N N N N FNTA high in NP −2.8 0.027254688 −1.6 13498 268 282 432 123 121 82 N N N N N N GBP2 high in NP −4.7 0.027220593 −1.6 13499 38 105 143 14 15 25 N N N N N N GSPT1 high in NP −3.6 0.027213774 −1.6 13500 128 439 235 71 117 65 N N N N N N HERC3 high in NP −2.6 0.027162632 −1.6 13501 30 64 46 16 16 19 N N N N P N TCEB2 high in NP −3.7 0.02714013 −1.6 13502 141 354 282 93 77 31 N N N N N N JOSD1 high in NP −2.5 0.027133311 −1.6 13503 302 513 476 126 142 192 N N N N P N ARPC5L high in NP −4.0 0.02711149 −1.6 13504 85 217 177 39 34 47 N N N N N N SLC25A34 high in NP −3.3 0.027104671 −1.6 13505 68 212 151 44 27 45 N N N N N N TMEM184A high in NP −4.8 0.02708626 −1.6 13506 57 197 230 18 48 29 N N N N N N CEBPZ high in NP −3.9 0.027065803 −1.6 13507 61 166 124 30 50 12 N N N N P N SERPINE1 high in NP −4.4 0.027031708 −1.6 13508 1133 2415 2172 950 280 520 N N N N N N ZAK high in NP −4.2 0.026982612 −1.6 13509 948 497 270 223 149 131 N N N N N N RAB5C high in NP −3.4 0.026965564 −1.6 13510 229 568 444 125 110 108 N N N N N N MAP4K5 high in NP −4.4 0.026958745 −1.6 13511 152 473 429 87 99 110 N N N N N N PGLS high in NP −3.3 0.026923969 −1.6 13512 228 102 178 44 52 27 N N N N N N FAM168B high in NP −2.7 0.026910331 −1.6 13513 76 157 135 63 44 31 N N N N N N PCBP2 high in NP −5.1 0.026903512 −1.6 13514 735 3085 2305 550 603 503 N N N N N N EDEM2 high in NP −2.9 0.026889874 −1.6 13515 30 22 35 11 9 9 N N N N N N GBAS high in NP −9.2 0.026850324 −1.6 13516 9 69 70 9 9 9 N N N N N N MLL5 high in NP −2.5 0.026843505 −1.6 13517 239 207 213 103 67 127 N N N N N N BDKRB2 high in NP −4.5 0.026836686 −1.6 13518 32 49 82 22 14 14 N N N N N N FLRT2 high in NP −3.3 0.026824412 −1.6 13519 164 103 81 31 49 40 N N N N N N C20orf199 high in NP −2.7 0.026810774 −1.6 13520 869 906 1455 324 394 430 N N N N N N WDR12 high in NP −2.9 0.026782816 −1.6 13521 23 27 20 12 15 12 N N N N N N PGD high in NP −8.7 0.026775997 −1.6 13522 128 826 1295 123 64 76 N N N N N N KIAA1522 high in NP −4.7 0.026749403 −1.6 13523 72 246 353 27 67 35 N N N N N N SLC2A3 high in NP −4.2 0.026663484 −1.6 13524 5354 1714 1792 500 431 1246 N N N N N N EPS8 high in NP −4.8 0.026649847 −1.6 13525 98 468 251 75 45 41 N N N N P N SEC22C high in NP −3.6 0.026563246 −1.6 13526 40 80 47 24 8 11 N N N N N N VIM high in NP −4.9 0.02652165 −1.6 13527 8396 44363 4535 1550 1493 3364 N N N N N N ZBTB41 high in NP −3.5 0.026505967 −1.6 13528 59 47 48 14 23 12 N N N N N N CCNY high in NP −3.3 0.026464371 −1.6 13529 386 414 196 150 103 90 N N N N N N C14orf126 high in NP −2.8 0.026457552 −1.6 13530 13 13 18 6 6 6 N N N N N N S100A8 high in NP −8.9 0.026403682 −1.6 13531 3 66 117 3 3 3 P P N N N N DPM1 high in NP −8.3 0.026370951 −1.6 13532 3 44 41 3 3 3 N N N N N N ANKRD46 high in NP −3.0 0.026358677 −1.6 13533 58 45 29 13 13 6 N N N N N N EGR1 high in NP −3.1 0.026330038 −1.6 13534 17527 9490 11906 4125 3306 6159 N N N N P N CHCHD3 high in NP −2.8 0.02623389 −1.6 13535 97 136 83 43 27 18 N N N N N N SSH1 high in NP −2.7 0.026227071 −1.6 13536 313 422 310 196 134 91 N N N N N N MAP3K7 high in NP −2.2 0.026199795 −1.6 13537 34 40 34 16 15 12 N N N N N N EN1 high in NP −2.6 0.026162291 −1.6 13538 35 58 35 10 10 10 P N N N N N TIMP3 high in NP −3.6 0.026121377 −1.6 13539 2051 2961 869 917 376 545 N N N N N N ZNF92 high in NP −3.3 0.026097511 −1.6 13540 11 14 26 5 5 5 N N N N N N ZNF32 high in NP −3.9 0.026090692 −1.6 13541 64 90 42 23 12 5 N N N N N N ADSS high in NP −3.9 0.026063416 −1.6 13542 31 64 104 15 12 17 N N N N N N NEIL1 high in NP −4.2 0.026051142 −1.6 13543 11 31 72 5 5 5 N N N N N N KRT10 high in NP −34.6 0.02602864 −1.6 13544 2 54 50 2 2 2 N N N N N N C19orf10 high in NP −7.3 0.026021821 −1.6 13545 116 576 867 113 58 25 N N N N N N NAA30 high in NP −3.3 0.025917491 −1.6 13546 20 63 38 13 13 13 NA NA N N N N EGLN1 high in NP −9.0 0.025875895 −1.6 13547 101 647 829 74 37 93 N N P N N N C16orf57 high in NP −4.5 0.025847937 −1.6 13548 35 135 128 24 15 14 N N N N N N BDKRB1 high in NP −3.3 0.02576611 −1.6 13549 785 238 239 120 65 55 N N N N N N KCNE4 high in NP −4.1 0.025759291 −1.6 13550 643 2445 1211 315 317 481 N N N N N N DCTN3 high in NP −3.5 0.025740198 −1.6 13551 143 127 85 27 45 10 P P N N N N IDH1 high in NP −3.4 0.025719741 −1.6 13552 89 43 36 11 16 18 N N N N N N PPAP2A high in NP −3.5 0.025712922 −1.6 13553 110 176 67 30 26 35 N N N N N N FLJ43663 high in NP −3.7 0.025676781 −1.6 13554 16 44 26 9 9 9 N N N N N N DCUN1D3 high in NP −4.6 0.025664507 −1.6 13555 349 532 394 79 45 247 N N N N N N NUPL1 high in NP −5.1 0.025588135 −1.6 13556 56 265 190 46 33 21 N N N N N N C18orf32 high in NP −11.1 0.025558132 −1.6 13557 14 115 83 7 2 5 N N N N N N MORC3 high in NP −3.9 0.025533583 −1.6 13558 64 202 132 47 23 24 N N N N N N DCAF8 high in NP −5.0 0.025491306 −1.6 13559 114 188 225 30 22 84 NA NA N N N N OSBPL8 high in NP −3.7 0.025445619 −1.6 13560 62 228 145 48 33 39 N N N N N N FUCA2 high in NP −2.6 0.025411524 −1.6 13561 41 117 44 15 14 9 N N N N N N DAB2 high in NP −5.8 0.025397886 −1.6 13562 278 1277 1424 177 181 260 N N N N N N ITGB1 high in NP −3.0 0.025385612 −1.6 13563 4287 6996 2650 1351 1541 820 N N N N N N UBA2 high in NP −5.3 0.025378793 −1.6 13564 79 308 239 43 43 30 N N N N N N CXCL13 high in NP −4.8 0.025366519 −1.6 13565 86 94 189 6 28 28 N N N N N N HNRPDL high in NP −5.2 0.0253597 −1.6 13566 88 413 270 41 51 53 N N N N N N ZNF775 high in NP −3.3 0.025352881 −1.6 13567 8 10 3 2 2 2 N N N N N N PFDN5 high in NP −8.5 0.025346062 −1.6 13568 183 1523 960 98 108 138 N N N N N N SFRS12IP1 high in NP −2.8 0.025339243 −1.6 13569 172 305 167 94 79 54 N N N N N N ISCA1 high in NP −38.0 0.02532015 −1.6 13570 3 68 57 3 3 3 N N N N P N TMEM45A high in NP −10.5 0.025306512 −1.6 13571 6 62 48 6 6 6 N N N N N N SLC36A4 high in NP −2.4 0.025299693 −1.6 13572 24 32 40 8 11 8 N N N N N N ACPL2 high in NP −5.1 0.025275145 −1.6 13573 13 51 10 7 7 7 N N N N N N ZBTB2 high in NP −2.9 0.025268326 −1.6 13574 100 131 75 29 20 39 N N N N N N MYL6 high in NP −2.7 0.025214456 −1.6 13575 2264 3915 2757 1071 1264 717 N N N N N N TCF7L1 high in NP −2.7 0.025191954 −1.6 13576 243 228 331 75 88 129 N N N N N P HIC1 high in NP −4.5 0.025178316 −1.6 13577 2715 195 359 69 72 92 N N N N N N IMMP1L high in NP −2.7 0.025144221 −1.6 13578 19 20 22 7 5 5 N N N N N N NDNL2 high in NP −4.6 0.02510808 −1.6 13579 36 128 106 22 12 13 N N N N N N RPL22 high in NP −2.6 0.025101262 −1.6 13580 2063 3138 2503 843 910 1194 N N N N N N ERMAP high in NP −2.6 0.025094443 −1.6 13581 29 20 30 8 11 8 N N N N N N TPCN1 high in NP −3.0 0.02506103 −1.6 13582 67 100 135 28 29 43 N N N N N N NOTCH1 high in NP −3.7 0.025047392 −1.6 13583 245 263 153 47 54 112 N N N N N N PLIN3 high in NP −2.7 0.025024889 −1.6 13584 409 679 627 230 155 245 NA NA N N N N ASPH high in NP −4.0 0.02501807 −1.6 13585 2267 1205 995 498 565 254 N N N N P N ABCC9 high in NP −2.3 0.024866008 −1.6 13586 54 117 74 26 25 21 N N N N N N RBP1 high in NP −3.0 0.024859189 −1.6 13587 75 54 33 15 16 12 N N N N N N GPR89A high in NP −38.5 0.02485237 −1.6 13588 2 85 56 2 2 2 N N N N P N TNFRSF10B high in NP −2.9 0.024845551 −1.6 13589 222 877 254 80 78 108 N N N N N N FBLN2 high in NP −2.4 0.024786908 −1.6 13590 85 92 107 32 31 40 N N N N N N SCCPDH high in NP −2.7 0.024780089 −1.6 13591 43 37 41 11 15 9 N N N N N N RAB1A high in NP −10.0 0.02473372 −1.6 13592 111 1178 768 78 77 79 N N N N N N VEGFA high in NP −4.4 0.024720082 −1.6 13593 9787 4027 3474 934 1283 2484 N N N N N N IARS2 high in NP −10.1 0.024703034 −1.6 13594 11 66 66 11 11 11 N N N N N N FOSL2 high in NP −3.0 0.02466894 −1.6 13595 1420 537 592 234 198 345 N N N N N N RB1 high in NP −2.4 0.024649847 −1.6 13596 25 36 51 13 13 13 N N P N N N LPXN high in NP −2.7 0.024585066 −1.6 13597 67 86 71 16 22 30 N N N N N N RNF103 high in NP −5.8 0.024578248 −1.6 13598 31 180 167 12 17 25 N N N N N N PLRG1 high in NP −7.3 0.024525742 −1.6 13599 25 127 91 9 14 10 N N N N P N S1PR3 high in NP −4.1 0.024512104 −1.6 13600 43 167 109 33 15 23 N N N N N N GHITM high in NP −3.9 0.024491647 −1.6 13601 46 181 188 50 16 20 N N N N N N FLNB high in NP −4.1 0.024478009 −1.6 13602 64 171 253 42 71 40 N N N N P N KIAA1430 high in NP −3.2 0.02447119 −1.6 13603 54 97 121 38 26 15 N N N N N N RANBP3 high in NP −6.0 0.024460961 −1.6 13604 35 182 159 30 25 20 N N P N N N C16orf72 high in NP −3.6 0.024448687 −1.6 13605 627 606 508 107 184 328 N N N N N N UBE2G1 high in NP −3.6 0.024405046 −1.6 13606 43 139 125 28 26 31 N N N N N N PCNP high in NP −24.2 0.024398227 −1.6 13607 8 225 218 8 8 11 N N N N N N FPGS high in NP −3.3 0.024383225 −1.6 13608 80 172 216 55 37 25 N N N N N N TBC1D9 high in NP −2.5 0.024330719 −1.6 13609 259 191 162 85 62 68 N N N N N N CPEB2 high in NP −3.9 0.0243239 −1.6 13610 194 647 168 43 47 99 N N N N N N MFHAS1 high in NP −3.3 0.024317081 −1.6 13611 149 124 73 32 31 39 N N N N N N FAM36A high in NP −3.8 0.024310263 −1.6 13612 76 225 195 32 52 30 N N N N P N ARFIP1 high in NP −4.7 0.024289806 −1.6 13613 36 109 132 21 21 13 N N N N N N WISP2 high in NP −9.9 0.024255029 −1.6 13614 25 329 245 9 16 25 N N N N N N FAM82A2 high in NP −5.3 0.02424821 −1.6 13615 41 73 54 9 26 9 N N N N N N SNRNP27 high in NP −16.3 0.024225707 −1.6 13616 16 213 271 9 12 5 N N N N N N CLPP high in NP −4.1 0.024203205 −1.6 13617 52 101 122 28 24 10 N N N N N N PRPS2 high in NP −6.7 0.024162291 −1.6 13618 18 105 56 7 12 7 N P N N N N WDR83 high in NP −2.6 0.02411865 −1.6 13619 17 19 41 6 6 6 NA NA N N N N MRPL49 high in NP −3.0 0.024089328 −1.6 13620 322 257 304 155 93 62 N N N N N N C4orf46 high in NP −4.1 0.024082509 −1.6 13621 197 243 116 41 30 82 N N N N N N SLC25A32 high in NP −10.9 0.024060007 −1.6 13622 24 281 137 15 12 6 N N N N N N MPZL1 high in NP −3.0 0.02402523 −1.6 13623 1347 1477 1131 808 525 307 N N N N P N BTG1 high in NP −3.8 0.024006137 −1.6 13624 1867 2722 3041 622 517 1355 N N N N N N SGMS2 high in NP −3.2 0.023999318 −1.6 13625 187 403 157 51 78 68 N N N N N N 8-Mar high in NP −11.7 0.023964541 −1.6 13626 8 149 147 10 8 8 NA NA N N N N MTCH2 high in NP −4.1 0.023957722 −1.6 13627 16 48 41 9 9 9 N N N N N N EBPL high in NP −11.5 0.023942039 −1.6 13628 3 60 62 3 3 3 N N N N N N FAM60A high in NP −3.3 0.023832254 −1.6 13629 643 495 417 191 325 98 N N N N N N CRIP1 high in NP −3.7 0.023768837 −1.6 13630 24 412 31 8 8 8 N N N N N N KCNS3 high in NP −4.0 0.023753154 −1.6 13631 13 16 16 6 6 6 N N N N N N C6orf106 high in NP −4.5 0.023746335 −1.6 13632 163 571 702 139 128 81 N N N N N N PRKCDBP high in NP −5.1 0.023723832 −1.6 13633 213 43 24 13 6 3 N N N N N N MYEOV2 high in NP −46.6 0.023717013 −1.6 13634 5 131 71 5 5 5 N N N N N N CAP1 high in NP −2.9 0.023675418 −1.6 13635 881 1085 702 386 360 165 N N N N N N CAPZA2 high in NP −6.9 0.023656325 −1.6 13636 46 329 209 20 41 18 N N N N P N C11orf58 high in NP −3.0 0.02364405 −1.6 13637 409 472 700 299 194 115 N N N N N N FOSB high in NP −4.0 0.023618138 −1.6 13638 38850 13869 11723 2769 3514 7274 N N N N N N FTO high in NP −3.8 0.023592226 −1.6 13639 154 143 84 54 17 30 N N N N N N CAB39 high in NP −5.4 0.023559495 −1.6 13640 48 204 229 18 37 29 N N N N N N MATR3 high in NP −3.6 0.023552676 −1.6 13641 257 531 422 135 109 166 N N N N P N LSM2 high in NP −2.9 0.023519945 −1.6 13642 178 110 167 60 29 25 N N N N N N TMEM101 high in NP −4.0 0.023493352 −1.6 13643 118 114 133 60 22 11 N N N N N N PHF2 high in NP −2.6 0.02344971 −1.6 13644 214 287 316 133 98 94 N N N N N N HIGD2A high in NP −3.9 0.023414252 −1.6 13645 83 180 230 40 29 36 N N N N N N YWHAG high in NP −3.1 0.02338493 −1.6 13646 1721 3410 2920 675 1007 1228 N N N N N N ZMYND19 high in NP −13.7 0.023371292 −1.6 13647 6 62 71 6 6 6 N N N N N N NDRG4 high in NP −2.2 0.023364473 −1.6 13648 24 31 26 13 13 13 N P N N N N LOC550643 high in NP −7.1 0.023357654 −1.6 13649 16 89 61 11 5 5 N N N N N N METTL9 high in NP −4.4 0.023350835 −1.6 13650 15 199 69 9 9 9 N N N N N N MGMT high in NP −7.9 0.023290147 −1.6 13651 19 43 55 11 6 3 N N N N N N SRP19 high in NP −58.4 0.023283328 −1.6 13652 3 92 94 3 3 3 N N N N N N SLC39A14 high in NP −3.4 0.023276509 −1.6 13653 501 1815 838 312 270 256 N N N N N N C5orf62 high in NP −5.9 0.023243778 −1.6 13654 170 1039 211 76 27 78 NA NA N N N N ADAMTS1 high in NP −3.2 0.023191954 −1.6 13655 236 537 367 154 79 140 N N N N N N RIOK3 high in NP −6.3 0.023160586 −1.6 13656 26 167 137 22 23 26 N N N N N N GOLM1 high in NP −3.6 0.023153767 −1.6 13657 322 213 159 35 65 70 N N N N N N GLTSCR2 high in NP −5.8 0.023127855 −1.6 13658 50 136 158 50 50 50 N N N N N N FAT1 high in NP −4.8 0.023121036 −1.6 13659 208 947 695 92 198 135 N N N N N N COPS7A high in NP −2.9 0.023114218 −1.6 13660 30 79 46 19 12 9 N N N N N N C18orf10 high in NP −2.5 0.023107399 −1.6 13661 39 51 67 20 14 14 N N N N N N PXMP2 high in NP −3.0 0.023095124 −1.6 13662 9 5 6 3 3 3 N N N N N N SCPEP1 high in NP −4.2 0.023088305 −1.6 13663 23 167 26 12 12 12 N N N N N N NAP1L1 high in NP −3.5 0.023069212 −1.6 13664 538 1309 1005 296 240 400 N N N N N N PIM2 high in NP −5.4 0.023062393 −1.6 13665 68 218 58 17 9 25 N N N N N N CSRP1 high in NP −3.6 0.023026253 −1.6 13666 3555 1728 2726 429 1061 517 N N N N N N TMEM189 high in NP −7.3 0.022976475 −1.6 13667 57 391 172 45 19 6 N N N N N N BMI1 high in NP −6.1 0.022969656 −1.6 13668 15 128 80 9 9 12 N N N N N N NDUFAB1 high in NP −8.1 0.022941698 −1.6 13669 23 159 87 15 11 6 N N N N N N BACH1 high in NP −3.4 0.022912376 −1.6 13670 85 210 213 43 45 66 N N N N N N SAE1 high in NP −3.4 0.022898738 −1.6 13671 268 258 235 119 51 61 N N N N N N ZFX high in NP −3.3 0.022876236 −1.6 13672 80 181 133 48 36 38 N N N N N N AQP7P3 high in NP −2.7 0.022869417 −1.6 13673 8 3 3 2 2 2 NA NA N N N N COX6C high in NP −14.8 0.022846914 −1.6 13674 14 258 247 6 3 11 N N N N N N PCMTD2 high in NP −2.7 0.022840095 −1.6 13675 90 64 64 30 18 14 N N N N N N CSNK1G2 high in NP −2.7 0.022796454 −1.6 13676 128 115 192 41 48 53 N N N N N N SNX7 high in NP −5.6 0.022782816 −1.6 13677 14 85 42 6 6 3 N N N N N N TMED10 high in NP −2.9 0.02274463 −1.6 13678 56 39 30 15 7 7 N N N N N N JUP high in NP −4.1 0.022718718 −1.6 13679 406 886 950 130 376 93 N N N N N N LHFPL2 high in NP −2.4 0.022696215 −1.6 13680 1757 2199 1963 867 770 992 N N P N N N MPRIP high in NP −2.6 0.022689397 −1.6 13681 403 477 452 142 217 157 N N N N N N HSPA1B high in NP −8.3 0.022668258 −1.6 13682 520 3199 3241 62 148 706 N N N N N N C7orf68 high in NP −9.5 0.022661439 −1.6 13683 5 111 207 5 5 5 NA NA N N N N TMOD4 high in NP −2.9 0.02265462 −1.6 13684 9 5 5 3 3 3 N N N N N N SOCS4 high in NP −4.2 0.022647801 −1.6 13685 18 101 81 18 18 18 N N N N N N COL7A1 high in NP −2.7 0.022623253 −1.6 13686 30 42 64 13 16 13 N N N N N N COPZ2 high in NP −3.3 0.022610979 −1.6 13687 231 56 47 15 18 13 N N N N N N MYL12A high in NP −2.9 0.022569383 −1.6 13688 1380 1540 1774 481 677 218 NA NA N N N N CCDC80 high in NP −4.3 0.022515513 −1.6 13689 2054 1160 1700 275 294 810 N N N N N N ISPD high in NP −3.0 0.022486192 −1.6 13690 15 10 11 9 9 9 NA NA N N N N COX17 high in NP −71.3 0.022472554 −1.6 13691 1 137 104 1 1 1 N N N N N N MTMR11 high in NP −5.1 0.022378452 −1.7 13692 141 42 46 25 11 14 N N N N N N TMEM138 high in NP −4.8 0.022357995 −1.7 13693 38 57 61 23 14 11 N N N N N N NUDT4P1 high in NP −40.9 0.022299352 −1.7 13694 14 475 166 5 2 8 N N N N N N TFCP2L1 high in NP −3.3 0.022247528 −1.7 13695 25 89 146 25 25 25 P P N N N N GSTK1 high in NP −4.0 0.02218343 −1.7 13696 90 173 249 16 53 33 N N N N N N CRYZL1 high in NP −5.5 0.022155472 −1.7 13697 13 36 19 6 6 6 N N N N N N PRNP high in NP −3.6 0.022148653 −1.7 13698 606 1403 743 182 288 355 N N N N N N GULP1 high in NP −8.7 0.022057961 −1.7 13699 8 111 195 8 8 8 N N N N N N EFCAB4A high in NP −6.2 0.022051142 −1.7 13700 15 21 54 4 4 7 N N N N N N EIF4EBP2 high in NP −2.5 0.022031367 −1.7 13701 462 659 526 301 243 245 N N N N P N C11orf95 high in NP −3.1 0.022018411 −1.7 13702 112 92 71 19 19 34 NA NA N N N N STRAP high in NP −5.2 0.022006137 −1.7 13703 265 978 816 111 123 165 N N N N N N PIGN high in NP −2.2 0.021978179 −1.7 13704 21 40 39 13 10 10 N N N N N N DR1 high in NP −2.7 0.021944085 −1.7 13705 138 205 118 46 37 54 N N N N N N GPN1 high in NP −3.7 0.021937266 −1.7 13706 23 24 11 7 7 7 N N N N N N KRTAP4-12 high in NP −84.0 0.021930447 −1.7 13707 1 171 125 1 1 1 N N N N N N TMX1 high in NP −3.2 0.021916809 −1.7 13708 92 93 133 25 21 42 NA NA N N N N PTPRG high in NP −2.6 0.02190999 −1.7 13709 102 125 134 57 40 36 N N N N N N SLC17A5 high in NP −3.7 0.021897716 −1.7 13710 64 135 70 26 27 14 N N N N N N AMIGO2 high in NP −8.7 0.021849301 −1.7 13711 100 175 262 33 69 24 N N N N N P RASSF2 high in NP −4.8 0.021835663 −1.7 13712 175 158 79 29 9 45 N N N N N N ZBTB8A high in NP −2.6 0.021797477 −1.7 13713 742 1120 1227 352 322 420 NA NA N N N N MICAL2 high in NP −5.6 0.021754518 −1.7 13714 80 177 84 18 48 17 N N N N N N IQCK high in NP −3.9 0.021747699 −1.7 13715 12 19 24 6 6 6 N N N N N N PMP22 high in NP −4.1 0.021734061 −1.7 13716 1687 2053 753 320 378 428 N N N N N N CD200 high in NP −2.7 0.02166178 −1.7 13717 29 69 30 10 10 10 N N N N N N CYFIP2 high in NP −4.2 0.021654961 −1.7 13718 37 50 26 8 6 14 N N N N N N RWDD2B high in NP −3.8 0.021648142 −1.7 13719 34 18 21 10 6 6 N N N N N N LRP1 high in NP −3.6 0.021641323 −1.7 13720 4343 2104 3277 958 532 1202 N N N N N N TMEM127 high in NP −3.2 0.021590863 −1.7 13721 495 832 551 351 192 151 N N N N N N ZNF264 high in NP −3.0 0.021577225 −1.7 13722 184 326 228 76 89 112 N N N N N N FOXJ3 high in NP −3.2 0.021510399 −1.7 13723 100 180 122 65 43 32 N N N N N N TPM1 high in NP −6.0 0.02150358 −1.7 13724 109 333 233 42 98 33 N N N N N P C7orf42 high in NP −2.5 0.021496761 −1.7 13725 2114 2218 1624 908 924 744 N N N N N N NCOA7 high in NP −4.3 0.021483123 −1.7 13726 184 408 494 90 104 115 N N N N N N HMGCS1 high in NP −3.5 0.021449028 −1.7 13727 69 122 151 43 30 27 N N N N N N NDUFV2 high in NP −4.3 0.021442209 −1.7 13728 90 242 228 49 44 29 N N N N N N SRP14 high in NP −3.1 0.02143539 −1.7 13729 76 118 89 36 8 20 N N N N N N YWHAE high in NP −17.3 0.021428571 −1.7 13730 49 943 552 28 29 39 N N P N N N ANKRA2 high in NP −5.4 0.021405387 −1.7 13731 11 16 19 5 5 5 N N N N N N EDF1 high in NP −3.9 0.021363791 −1.7 13732 327 584 737 180 160 63 N N N N N N DARC high in NP −6.9 0.021344698 −1.7 13733 806 71 62 6 9 27 N N N N N N RFC2 high in NP −6.0 0.021337879 −1.7 13734 13 22 37 6 6 6 N N N N N N C11orf73 high in NP −3.5 0.021292192 −1.7 13735 55 56 26 15 12 9 N N N N N N CNNM4 high in NP −3.6 0.021251279 −1.7 13736 56 104 91 20 18 37 N N N N N N NGFR high in NP −6.1 0.021237641 −1.7 13737 2061 339 266 42 134 71 N N N N N N NTRK2 high in NP −3.1 0.021183089 −1.7 13738 110 166 97 49 61 52 N N N N N N SMAD5 high in NP −2.7 0.02117627 −1.7 13739 36 97 82 28 26 27 N N N N N N F5 high in NP −2.6 0.021162632 −1.7 13740 211 364 290 76 87 90 N P N N N N RPS6KA1 high in NP −6.0 0.021142175 −1.7 13741 17 64 67 11 11 11 N N N N N N ZNF549 high in NP −4.9 0.021128537 −1.7 13742 26 60 33 12 9 16 N N N N N N B4GALT1 high in NP −2.7 0.021095124 −1.7 13743 1180 1749 1244 438 528 622 N N N N N N ZCCHC7 high in NP −2.6 0.021075349 −1.7 13744 34 33 30 11 12 7 N N N N N N ZNF805 high in NP −2.5 0.021060348 −1.7 13745 43 119 84 29 28 28 NA NA N N N N EMILIN2 high in NP −3.7 0.020972383 −1.7 13746 64 151 127 30 27 27 N N N N P N CRIM1 high in NP −7.2 0.0209567 −1.7 13747 32 256 131 25 27 21 N N N N N N TMED7 high in NP −10.8 0.020911695 −1.7 13748 81 1043 355 71 22 30 N N N N N N PPP1R1A high in NP −6.0 0.020904876 −1.7 13749 13 22 31 6 6 6 N N N N N N RBM15 high in NP −6.1 0.020878282 −1.7 13750 21 97 46 9 9 12 N N N N N N NDUFB11 high in NP −2.6 0.020871463 −1.7 13751 156 157 141 59 41 41 N N N N N N FMO1 high in NP −5.5 0.020772588 −1.7 13752 488 37 55 6 9 17 N N N N N N DPCD high in NP −7.9 0.020765769 −1.7 13753 20 24 16 4 4 10 NA NA N N N N SEC61B high in NP −127.1 0.020753495 −1.7 13754 2 257 195 2 2 2 N N N N N N CTSB high in NP −4.1 0.020746676 −1.7 13755 926 1537 2749 732 344 316 N N N N N N ADAM12 high in NP −4.2 0.020720764 −1.7 13756 385 131 115 26 41 55 N N N N N N PLOD2 high in NP −5.1 0.020683259 −1.7 13757 14 118 214 14 14 17 N N N N N N LMCD1 high in NP −4.3 0.020658711 −1.7 13758 339 258 115 47 64 33 N N N N N N SYTL2 high in NP −2.8 0.020636209 −1.7 13759 107 41 39 20 17 17 N N N N N N KIAA0090 high in NP −3.1 0.020620525 −1.7 13760 36 86 64 13 19 18 N N N N N N RALA high in NP −3.5 0.020613706 −1.7 13761 187 316 341 88 102 86 N N N N N N TNFRSF10D high in NP −5.6 0.020578248 −1.7 13762 33 142 149 21 19 25 N N N N N N NFU1 high in NP −4.9 0.020571429 −1.7 13763 56 64 48 24 9 7 N N N N N N CCDC120 high in NP −3.2 0.020524378 −1.7 13764 156 318 290 80 88 43 N N N N N N EI24 high in NP −3.4 0.020501875 −1.7 13765 263 528 333 168 100 63 N N N N N N HNRNPA1 high in NP −42.0 0.020468462 −1.7 13766 11 484 241 9 5 5 N N N N N N CTBP1 high in NP −2.8 0.020461643 −1.7 13767 545 695 447 255 224 152 N N N N N N TACSTD2 high in NP −8.6 0.020403682 −1.7 13768 256 2584 3391 88 394 51 P N N N P N TRAM1 high in NP −4.4 0.020279577 −1.7 13769 608 620 427 257 128 73 N N N N N N TRAPPC6B high in NP −2.9 0.020272758 −1.7 13770 25 53 37 13 13 13 N N N N N N TFPI high in NP −4.9 0.020250256 −1.7 13771 473 3035 2259 665 115 156 N N N N N N MRPL54 high in NP −5.7 0.020236618 −1.7 13772 19 68 58 9 6 6 N N N N N N MRPL21 high in NP −7.5 0.020214797 −1.7 13773 16 61 43 9 5 5 N N N N N N RAB5B high in NP −2.5 0.020171838 −1.7 13774 757 649 637 318 214 269 N N N N N N QARS high in NP −3.6 0.020096147 −1.7 13775 34 142 68 15 14 10 N N N N N N TP53INP1 high in NP −3.6 0.020075009 −1.7 13776 49 75 110 28 13 21 N N P N P N ERH high in NP −56.1 0.020043641 −1.7 13777 12 391 188 8 6 6 N N N N N N RHOA high in NP −2.6 0.020023184 −1.7 13778 3667 2648 3340 1373 1050 990 N N N N N N RTN2 high in NP −3.7 0.019966587 −1.7 13779 39 19 15 7 5 2 N N N N N P ATP5F1 high in NP −6.3 0.01989226 −1.7 13780 101 402 205 42 14 54 N N N N N N THY1 high in NP −4.8 0.019885442 −1.7 13781 491 444 150 45 71 89 N N N N P N TMEM30A high in NP −4.2 0.019849301 −1.7 13782 263 746 766 222 142 116 N N N N N N PSMD8 high in NP −5.0 0.019734743 −1.7 13783 366 1385 1008 256 205 88 N N N N N N MAF high in NP −4.9 0.019727924 −1.7 13784 1210 579 740 190 143 502 N N N N N N SLC39A9 high in NP −2.8 0.019721105 −1.7 13785 154 177 186 81 40 54 N N N N N N ZC3H4 high in NP −2.9 0.019700648 −1.7 13786 105 139 187 42 48 53 N N N N N N ELF2 high in NP −2.7 0.019693829 −1.7 13787 72 75 67 26 24 29 N N N N N N EFR3A high in NP −2.9 0.01968701 −1.7 13788 45 70 71 22 23 13 N N N N N N C17orf85 high in NP −4.7 0.019641323 −1.7 13789 28 107 76 14 20 12 N N N N N N PNP high in NP −3.3 0.019592226 −1.7 13790 992 644 677 258 295 140 NA NA N N N N TOMM22 high in NP −6.8 0.019533583 −1.7 13791 115 875 333 84 41 35 N N N N N N AKR1B1 high in NP −12.3 0.019494033 −1.7 13792 27 519 489 35 11 14 N N N N N N CHRNB1 high in NP −2.7 0.019487214 −1.7 13793 36 36 41 11 5 10 N N N N P N TPM4 high in NP −4.9 0.019428571 −1.7 13794 252 1358 655 171 159 76 N N N N N N LZTFL1 high in NP −7.9 0.019421752 −1.7 13795 11 40 25 5 5 5 N P N N N N HBP1 high in NP −13.9 0.019401296 −1.7 13796 21 424 396 23 15 21 N N N N N P TBC1D10B high in NP −2.8 0.019387658 −1.7 13797 105 181 136 57 39 51 N N N N N P LAMP1 high in NP −3.5 0.019366519 −1.7 13798 858 1284 727 493 216 214 N N N N N N NDUFA12 high in NP −5.1 0.019307876 −1.7 13799 26 68 66 9 8 3 N N N N N N TFPI2 high in NP −2.8 0.019264916 −1.7 13800 44 99 38 15 11 13 N N N N N N NDUFA4 high in NP −13.4 0.019258098 −1.7 13801 51 439 322 15 24 16 N N N N N N F11R high in NP −5.1 0.01924446 −1.7 13802 68 260 223 39 47 29 N N N N N N WEE1 high in NP −2.9 0.019216502 −1.7 13803 474 713 783 204 286 206 N N N N N N ZHX2 high in NP −2.9 0.019209683 −1.7 13804 85 123 90 37 32 21 N N N N N N NEK3 high in NP −3.7 0.019196045 −1.7 13805 20 6 8 4 4 4 N N N N P N IRAK2 high in NP −4.1 0.019182407 −1.7 13806 255 585 189 122 41 55 N N N N N N RFC3 high in NP −8.3 0.019142857 −1.7 13807 13 29 27 6 6 6 N P N N N N C10orf75 high in NP −3.3 0.019136038 −1.7 13808 41 28 34 9 5 10 NA NA N N N N EFEMP1 high in NP −5.4 0.01911149 −1.7 13809 43 545 97 13 20 13 N N N N N N SFRS2B high in NP −3.2 0.019091033 −1.7 13810 65 161 102 39 20 26 N N N N N N ITM2B high in NP −4.1 0.01907194 −1.7 13811 2315 2259 962 487 430 554 N N N N N N SLC25A17 high in NP −6.7 0.019065121 −1.7 13812 13 64 30 6 6 6 N N N N N N VPS37A high in NP −7.2 0.019042618 −1.7 13813 20 187 100 14 14 14 N N N N N N NCRNA00116 high in NP −4.9 0.0190358 −1.7 13814 18 100 53 9 6 6 NA NA N N N N SFRS2 high in NP −4.4 0.019028981 −1.7 13815 894 2681 2304 357 584 511 N N N N N N PLK2 high in NP −4.9 0.019016025 −1.7 13816 43 198 144 19 19 34 N N N N N N TACR1 high in NP −8.5 0.0189642 −1.7 13817 17 35 42 11 11 11 N N N N N N SLC39A1 high in NP −5.1 0.018951926 −1.7 13818 124 402 329 78 55 19 N N N N N N SOX17 high in NP −4.9 0.018938288 −1.7 13819 238 54 35 15 7 7 P P N N P N HERC4 high in NP −3.0 0.018882373 −1.7 13820 24 53 61 15 13 13 N N N N N N SH3BGR high in NP −8.8 0.018875554 −1.7 13821 11 31 29 5 5 5 N N N N N N TUBA1C high in NP −17.3 0.01882032 −1.7 13822 118 2213 986 49 83 39 N N N N N N ZFP36L2 high in NP −3.6 0.018806683 −1.7 13823 3559 4435 3293 924 996 1902 N N N N N N SCMH1 high in NP −3.1 0.018799864 −1.7 13824 28 51 58 18 12 12 N N N N N N PELI1 high in NP −3.1 0.018775997 −1.7 13825 992 833 914 224 319 437 N N N N N N PICALM high in NP −4.7 0.018762359 −1.7 13826 212 677 455 88 127 83 N N N N N N SPAG7 high in NP −2.9 0.01875554 −1.7 13827 138 249 182 43 64 41 N N N N N N C1orf43 high in NP −13.3 0.018748721 −1.7 13828 23 223 211 15 11 6 N N N N N N TAP1 high in NP −4.2 0.018728265 −1.7 13829 309 318 151 63 33 76 N N N N N N TWF2 high in NP −3.8 0.018713945 −1.7 13830 86 30 66 15 9 6 N N N N N N NFYC high in NP −3.9 0.018707126 −1.7 13831 57 106 135 24 19 31 N N N N N N PLEKHB2 high in NP −3.0 0.018686669 −1.7 13832 512 797 720 274 261 280 N N N N N N CPEB3 high in NP −4.3 0.018660757 −1.7 13833 22 51 70 13 11 11 N N N N N N XRN2 high in NP −5.3 0.018653938 −1.7 13834 118 479 344 80 52 52 N N N N N N SLC25A6 high in NP −2.9 0.018647119 −1.7 13835 4226 3665 5231 1143 1763 1464 N N N N N N TAC1 high in NP −12.0 0.0186403 −1.7 13836 21 221 260 9 9 18 P N N N N N SPOCK1 high in NP −4.2 0.018606205 −1.7 13837 187 78 42 20 15 10 N N N N N N SLIT3 high in NP −4.4 0.018592567 −1.7 13838 297 199 80 39 20 31 N N P N N N PDK3 high in NP −4.9 0.018554381 −1.7 13839 17 48 36 8 6 6 N N N N N N SHOC2 high in NP −2.6 0.018542107 −1.7 13840 150 198 161 52 65 54 N N N N N N UPP1 high in NP −4.6 0.018455506 −1.7 13841 1882 723 2318 465 311 269 N N N N N N APPL1 high in NP −2.9 0.018441868 −1.7 13842 132 194 110 50 57 44 N N N N N N GNPTG high in NP −3.3 0.018435049 −1.7 13843 25 34 43 10 7 7 N N N N N N STS high in NP −2.7 0.018409137 −1.7 13844 37 29 33 11 11 11 N P N N N N CASC4 high in NP −3.3 0.018351176 −1.7 13845 1068 680 507 281 185 191 N N N N N P FCGRT high in NP −2.7 0.018344357 −1.7 13846 601 504 394 183 127 164 N N N N N N THBS2 high in NP −5.5 0.018282987 −1.7 13847 483 1965 1667 372 187 282 N N N N N N SFRS3 high in NP −3.9 0.018276168 −1.7 13848 794 1941 1398 536 377 383 N N N N N N RAP2B high in NP −4.2 0.018260484 −1.7 13849 326 933 920 113 235 144 N N N N N N IGFBP7 high in NP −5.4 0.018253665 −1.7 13850 543 2495 203 119 41 92 N N N N N N SLC5A3 high in NP −3.4 0.018246846 −1.7 13851 75 144 129 31 33 50 N N N N N N MKRN2 high in NP −5.6 0.018212751 −1.7 13852 30 105 116 20 17 17 N N N N N N RDH14 high in NP −2.5 0.018205932 −1.7 13853 73 68 73 23 23 14 N N N N N N MFF high in NP −3.1 0.018175247 −1.7 13854 23 45 59 10 6 6 N N N N N N C1orf122 high in NP −4.0 0.018168428 −1.7 13855 49 133 83 10 16 18 N N N N P N SKP1 high in NP −6.2 0.018161609 −1.7 13856 522 2190 2070 269 324 256 N N N N N N RHOB high in NP −6.8 0.018149335 −1.7 13857 484 2430 1527 369 228 220 N N N N N N TIAL1 high in NP −7.7 0.018142516 −1.7 13858 62 257 246 34 31 30 N N N N N N PTGES3 high in NP −11.9 0.018102284 −1.7 13859 374 3535 3437 229 169 287 N N N N N N RRP1B high in NP −3.2 0.018095465 −1.7 13860 68 266 142 24 35 34 N N N N N N HECTD1 high in NP −4.6 0.018061371 −1.7 13861 46 176 199 41 30 42 N N N N N P SNX25 high in NP −11.1 0.018037504 −1.7 13862 13 42 39 7 7 7 N N N N N N GNAS high in NP −11.9 0.017954995 −1.7 13863 419 3537 3082 244 270 230 P N P N N N DSC2 high in NP −7.6 0.017948176 −1.7 13864 62 206 409 23 50 26 N P N N N N SMAD7 high in NP −4.2 0.017929083 −1.7 13865 111 513 148 34 30 48 N N N N N N HEXIM1 high in NP −3.8 0.017901807 −1.7 13866 209 400 193 46 52 101 N N N N N N PAN3 high in NP −3.2 0.01788135 −1.7 13867 180 337 348 80 110 63 N N N N N N NAPA high in NP −3.0 0.017865667 −1.7 13868 899 484 596 239 181 162 N N N N N N TMX2 high in NP −5.1 0.017852029 −1.7 13869 58 237 163 28 28 21 NA NA N N N N RCN1 high in NP −4.3 0.017838391 −1.7 13870 325 889 691 184 151 135 N N N N N N GMCL1 high in NP −2.8 0.017823389 −1.7 13871 15 5 6 2 2 2 N N N N N N RBBP4 high in NP −3.2 0.017802932 −1.7 13872 256 399 540 151 130 149 N N N N N N ANTXR2 high in NP −3.5 0.017774974 −1.8 13873 115 92 117 27 29 39 N N N N N N ANTXR1 high in NP −3.9 0.01774088 −1.8 13874 354 180 121 45 47 59 N N N N N N TMEM167A high in NP −2.7 0.01770133 −1.8 13875 127 205 173 69 45 40 N N N N N N KIAA1467 high in NP −6.5 0.017667235 −1.8 13876 15 40 35 9 9 9 N N N N N N RCOR3 high in NP −3.1 0.017637913 −1.8 13877 66 60 47 17 20 24 N N N N N N PGAP2 high in NP −2.8 0.017609956 −1.8 13878 28 29 60 12 12 12 NA NA N N N N BET1 high in NP −13.1 0.017569724 −1.8 13879 11 43 66 5 5 5 N N N N N N C2orf40 high in NP −9.6 0.017526764 −1.8 13880 759 435 73 18 69 16 N N N N N N MLF1 high in NP −5.7 0.017519945 −1.8 13881 19 120 50 6 6 6 N N N N N N CXCL6 high in NP −17.7 0.017513126 −1.8 13882 81 982 1002 42 21 47 N N N N N N SLC41A2 high in NP −4.0 0.017506308 −1.8 13883 42 12 11 6 4 4 N N N N N N TMEM69 high in NP −9.4 0.017465394 −1.8 13884 39 28 29 13 3 3 N N N N N N SMG7 high in NP −2.8 0.017450392 −1.8 13885 64 69 63 32 19 20 N N N N P N IMP3 high in NP −5.0 0.017443573 −1.8 13886 106 283 195 52 41 21 N N N N N N COL15A1 high in NP −4.4 0.017436754 −1.8 13887 531 172 158 75 54 35 N N N N N N OS9 high in NP −4.7 0.017363109 −1.8 13888 89 228 134 14 33 31 N N N N N N FBLN1 high in NP −4.2 0.017335152 −1.8 13889 4078 4088 1501 506 752 912 N N N N N N DYNLT3 high in NP −4.7 0.017318104 −1.8 13890 57 214 163 42 12 15 N P N N N N PREB high in NP −3.1 0.017266962 −1.8 13891 49 58 108 20 15 14 N N N N N N PARVA high in NP −3.0 0.017253324 −1.8 13892 182 117 167 53 44 54 N N N N N N ARPP19 high in NP −3.0 0.017230822 −1.8 13893 790 1291 852 491 371 259 NA NA N N N N LMAN1 high in NP −4.1 0.017203546 −1.8 13894 48 141 154 43 20 24 N N N N N N WIPF2 high in NP −2.7 0.017196727 −1.8 13895 263 262 256 138 90 83 N N N N N N RPL14 high in NP −2.9 0.01717627 −1.8 13896 1652 2715 2418 638 781 804 N N N N N N PSMD4 high in NP −3.7 0.017146949 −1.8 13897 178 253 230 84 36 38 N N N N N N CD59 high in NP −3.5 0.01712581 −1.8 13898 1515 2640 4337 876 892 859 N N N N N N NUMBL high in NP −2.5 0.017027617 −1.8 13899 86 91 102 34 29 35 N N N N N N INSIG2 high in NP −4.5 0.017020798 −1.8 13900 83 96 143 43 17 13 N N N N N N TIMELESS high in NP −3.0 0.016998295 −1.8 13901 31 23 39 7 8 8 N N N N N N SCN4B high in NP −3.6 0.016923287 −1.8 13902 359 106 109 38 26 26 N N N P N N CMC1 high in NP −5.4 0.016869417 −1.8 13903 9 7 6 2 2 2 N N N N N N GHDC high in NP −3.2 0.016855779 −1.8 13904 66 32 43 10 8 11 N N N N N N ZBTB38 high in NP −3.1 0.016842141 −1.8 13905 67 72 105 37 22 22 N N N N N N POTEE high in NP −5.6 0.016806001 −1.8 13906 7 7 5 1 1 1 NA NA N N N N TOB1 high in NP −3.5 0.016799182 −1.8 13907 395 1057 476 140 136 196 N N N N P N EIF1 high in NP −8.4 0.016778043 −1.8 13908 701 5034 3840 251 302 532 N N N N N N VPS35 high in NP −5.1 0.016737129 −1.8 13909 88 173 270 37 42 24 N N N N N N TUBA1B high in NP −39.8 0.016703716 −1.8 13910 92 3226 2641 45 54 48 N N N N N N EFNA3 high in NP −7.7 0.016623253 −1.8 13911 17 31 18 11 11 11 N N N N N N CAT high in NP −3.4 0.01660075 −1.8 13912 95 74 55 25 12 18 N N N N N N PPP3R1 high in NP −7.6 0.016587112 −1.8 13913 50 248 209 22 29 35 N N N N N N LOC728661 high in NP −4.2 0.016559154 −1.8 13914 NA NA NA NA NA NA N N N N N N PITRM1 high in NP −10.3 0.016552335 −1.8 13915 29 121 167 17 20 17 N N N N N N C7orf70 high in NP −7.9 0.016545517 −1.8 13916 20 15 29 8 4 4 NA NA N N N N CXCL12 high in NP −7.3 0.016505967 −1.8 13917 3763 1378 637 150 166 503 N N N N N N MYL12B high in NP −4.4 0.016492329 −1.8 13918 1035 2175 1877 393 567 198 NA NA N N N N DPAGT1 high in NP −4.0 0.016463689 −1.8 13919 24 67 61 10 13 8 N N N N N N C10orf46 high in NP −3.0 0.016390044 −1.8 13920 109 155 136 54 55 34 N N N N N N ZNF581 high in NP −4.2 0.016376406 −1.8 13921 62 131 167 22 16 26 N N N N P N CCDC111 high in NP −7.8 0.016353904 −1.8 13922 13 15 22 6 6 6 N N N N N N ACLY high in NP −3.4 0.016340266 −1.8 13923 32 74 64 21 21 21 N N N N N P ATG7 high in NP −3.4 0.016300716 −1.8 13924 41 82 91 25 13 13 N N N N P N PON2 high in NP −8.1 0.016293897 −1.8 13925 18 84 58 6 6 9 N N N N N N SIX4 high in NP −3.2 0.016278213 −1.8 13926 47 72 55 21 21 27 N N N N N N TMEM93 high in NP −19.2 0.016256393 −1.8 13927 13 159 194 6 2 2 N N N N N N CORO1C high in NP −5.4 0.016241391 −1.8 13928 41 182 148 32 30 36 N N N N N N CNN3 high in NP −3.2 0.016234572 −1.8 13929 4139 2027 2375 790 772 1019 N N N N N N IFFO2 high in NP −4.4 0.016214115 −1.8 13930 327 375 419 68 176 81 N N N N N N RAB28 high in NP −6.9 0.016164337 −1.8 13931 10 10 9 4 4 4 N N N N N N PTP4A3 high in NP −5.6 0.01606819 −1.8 13932 329 91 74 14 34 12 N N N N P N RAB10 high in NP −12.9 0.016061371 −1.8 13933 53 585 579 31 35 32 N N N N N N HERPUD1 high in NP −7.0 0.016004773 −1.8 13934 174 765 660 110 83 45 N N N N N N PRKAR1A high in NP −8.7 0.01598909 −1.8 13935 823 4123 4704 606 296 464 N N N N N N PARD3 high in NP −3.4 0.015975452 −1.8 13936 26 41 37 15 15 15 N N N N N N TAOK1 high in NP −2.8 0.015947494 −1.8 13937 36 53 69 21 19 19 N N N N N N CAP2 high in NP −3.9 0.015907944 −1.8 13938 37 19 14 8 8 8 N N N N N N BANF1 high in NP −4.9 0.015879304 −1.8 13939 987 445 334 155 105 52 N N N N N N LSM1 high in NP −3.0 0.015872486 −1.8 13940 49 58 88 14 14 13 N N N N N N BMPR2 high in NP −3.6 0.015829526 −1.8 13941 206 174 127 59 53 56 N N N N P N C2orf28 high in NP −4.0 0.015800205 −1.8 13942 234 174 138 49 43 15 N N N N N N MRPL22 high in NP −5.3 0.015786567 −1.8 13943 24 28 13 7 3 3 N N N N N N CEBPG high in NP −3.3 0.015764064 −1.8 13944 101 259 159 34 49 42 N N N N N N LOC339788 high in NP −4.8 0.015757245 −1.8 13945 18 2 4 2 2 2 N N N N N N CDKN2C high in NP −3.6 0.015714286 −1.8 13946 37 44 65 9 5 13 N N N N N N C11orf59 high in NP −4.4 0.015688374 −1.8 13947 57 171 115 29 13 7 N N N N N N CMTM8 high in NP −4.8 0.01567269 −1.8 13948 152 50 68 12 20 8 N N N N N N SELK high in NP −5.9 0.015659052 −1.8 13949 320 1031 1037 171 119 138 N P N N N N ZBED3 high in NP −9.2 0.015630413 −1.8 13950 115 18 36 12 7 4 N N N N N N AFAP1 high in NP −2.7 0.015574497 −1.8 13951 110 118 97 36 32 39 N N N N N N TSPAN13 high in NP −12.5 0.015545176 −1.8 13952 18 99 130 7 10 7 N N N N N N COL5A1 high in NP −4.5 0.015516536 −1.8 13953 3609 539 493 143 130 235 N N P N N N BTG2 high in NP −4.6 0.015455847 −1.8 13954 2157 911 450 205 138 230 N N N N N N LEPR high in NP −3.1 0.015429935 −1.8 13955 452 693 518 160 141 204 N N N N N N HSD17B14 high in NP −2.9 0.015423116 −1.8 13956 66 36 43 15 14 13 N N N P N N FGFBP2 high in NP −4.9 0.015409478 −1.8 13957 20 57 11 4 4 7 N N N N N N TNFSF9 high in NP −4.3 0.015402659 −1.8 13958 231 153 104 29 11 46 N P N N N N SH3GL1 high in NP −3.2 0.01539584 −1.8 13959 341 450 545 179 134 70 N N N N N N TSC22D1 high in NP −3.5 0.015367883 −1.8 13960 823 1620 1324 263 286 486 N N P N N N IFI6 high in NP −3.5 0.015346744 −1.8 13961 2617 1107 1497 505 303 431 N N P N N N IL13RA1 high in NP −3.1 0.015314013 −1.8 13962 196 207 155 43 73 46 N N N N N N EGFL6 high in NP −8.8 0.015307194 −1.8 13963 175 14 8 4 4 7 P P N N N N MFAP5 high in NP −5.8 0.015293556 −1.8 13964 345 383 93 15 27 54 N N N N N N RNF2 high in NP −3.7 0.015279918 −1.8 13965 128 208 93 20 31 33 N N N N N N BBS1 high in NP −3.2 0.015253324 −1.8 13966 34 34 55 13 16 13 N N N N N N DUSP10 high in NP −6.8 0.015239686 −1.8 13967 19 57 52 10 8 8 N N N N N N ZHX1 high in NP −3.2 0.015148994 −1.8 13968 92 86 65 27 14 25 N N N N P N TMED3 high in NP −4.1 0.01510058 −1.8 13969 194 198 116 52 19 32 N P N N N N CBR1 high in NP −3.2 0.015093761 −1.8 13970 130 129 143 49 30 30 N N N N N N SEC62 high in NP −3.4 0.015086942 −1.8 13971 279 667 395 179 139 102 N N N N N N NFIL3 high in NP −4.3 0.015012615 −1.8 13972 215 659 628 64 43 127 N N N N N N MPST high in NP −3.4 0.014971701 −1.8 13973 79 118 132 35 19 23 N N N N N N SETD7 high in NP −3.6 0.014956018 −1.8 13974 33 110 92 23 20 20 N N N N P N ZDHHC4 high in NP −4.5 0.014949199 −1.8 13975 99 65 44 20 10 13 N N N N N N MUSTN1 high in NP −3.3 0.014933515 −1.8 13976 23 36 25 4 4 7 N N N N N N AMIGO1 high in NP −3.8 0.014926696 −1.8 13977 15 5 10 4 4 4 N N N N N N CBX1 high in NP −3.5 0.014911695 −1.8 13978 90 152 278 23 35 31 N N N N N N PROS1 high in NP −3.0 0.01489942 −1.8 13979 55 126 43 18 17 17 N N N N N N DAB2IP high in NP −3.8 0.014885782 −1.8 13980 66 105 99 17 35 24 N N P N N N PRDX2 high in NP −3.4 0.014868735 −1.8 13981 157 226 140 55 34 18 N N N N N N CIR1 high in NP −2.6 0.014861916 −1.8 13982 36 41 54 14 12 13 NA NA N N N N A2M high in NP −5.3 0.014836004 −1.8 13983 576 817 246 85 109 106 N N N N N N ZFAND1 high in NP −3.2 0.014771906 −1.8 13984 57 88 49 21 17 14 N N N N N N RFK high in NP −3.1 0.014758268 −1.8 13985 19 27 22 8 8 8 N N N N N N GADD45B high in NP −8.2 0.014751449 −1.8 13986 11200 3350 3907 380 1063 1319 N N N N N N SH3BGRL3 high in NP −4.2 0.01474463 −1.8 13987 587 875 1248 243 287 89 N N N N N N EIF3G high in NP −4.0 0.014660757 −1.8 13988 182 492 345 89 75 53 N N N N N N CFDP1 high in NP −8.9 0.014620525 −1.8 13989 26 74 123 10 7 4 N N N N N N C7orf60 high in NP −6.0 0.014590522 −1.8 13990 30 102 104 11 14 15 N N N N N N CHMP2A high in NP −8.0 0.0145612 −1.8 13991 81 359 436 39 19 37 N N N N N N RPN2 high in NP −5.6 0.014527787 −1.8 13992 131 493 400 78 41 27 N N N N N N PITPNA high in NP −3.8 0.014520968 −1.8 13993 98 160 195 48 34 32 N N N N N N PDZRN3 high in NP −4.3 0.014443914 −1.8 13994 71 228 83 20 19 30 N N N N N N ADD3 high in NP −3.7 0.014423457 −1.8 13995 88 117 63 20 21 30 N N N N N N C1S high in NP −5.2 0.014370269 −1.8 13996 331 1210 781 116 105 214 N N N N N N C20orf11 high in NP −4.4 0.01436345 −1.8 13997 186 405 405 99 72 71 N N N N N N ECH1 high in NP −4.3 0.014328674 −1.8 13998 132 87 68 17 29 17 N N N N N N KLF4 high in NP −5.3 0.014321855 −1.8 13999 346 1183 436 83 83 200 N N N N N N DPH5 high in NP −3.9 0.014308899 −1.8 14000 86 40 86 9 18 13 N N N N N N SPRED2 high in NP −2.8 0.01430208 −1.8 14001 73 134 100 32 25 31 N N N N N N COBRA1 high in NP −3.2 0.014248892 −1.8 14002 152 101 133 40 31 23 N N N N N N MRPS34 high in NP −3.2 0.014235254 −1.8 14003 140 145 107 42 35 23 N N N N N N RPS5 high in NP −4.8 0.014216161 −1.8 14004 3846 10762 6994 1457 1975 1442 N N N N N N RNF146 high in NP −3.1 0.014171156 −1.8 14005 113 158 174 40 28 44 N N N N N N NFKBIL1 high in NP −4.1 0.014157518 −1.8 14006 50 59 78 19 16 9 N N N N N N IFT52 high in NP −5.3 0.014096829 −1.9 14007 43 28 31 13 6 6 N N N N N N KLHL21 high in NP −6.2 0.01409001 −1.9 14008 889 2638 1696 121 265 562 N N N N N N SAMD4B high in NP −2.8 0.014077054 −1.9 14009 158 208 160 75 56 50 N N N N N N DGCR2 high in NP −3.6 0.014035459 −1.9 14010 112 186 198 61 40 21 N N N N N N PMPCA high in NP −6.4 0.01402864 −1.9 14011 72 229 235 34 36 21 N N N N N N FAM110B high in NP −2.9 0.014021821 −1.9 14012 49 71 54 23 15 13 N N N N P N CCL26 high in NP −5.3 0.014015002 −1.9 14013 13 19 20 2 2 5 N N N N N N C6orf168 high in NP −3.6 0.014001364 −1.9 14014 36 46 48 24 24 24 N N N N N N RHOJ high in NP −3.6 0.013939993 −1.9 14015 60 32 49 7 10 13 N N N N N N SERPINF1 high in NP −4.9 0.013926355 −1.9 14016 138 1183 174 31 26 46 N N N N N N RPL30 high in NP −2.8 0.013855438 −1.9 14017 9523 12544 9949 3084 3239 3833 N N N N N N PLSCR3 high in NP −3.6 0.013848619 −1.9 14018 185 139 172 50 36 14 N N N N P N FAM20A high in NP −3.0 0.0138418 −1.9 14019 83 113 72 33 24 28 N N N N N N CDH1 high in NP −7.6 0.013815888 −1.9 14020 432 935 1498 76 331 56 P N N N N N FBXL5 high in NP −4.1 0.013772247 −1.9 14021 34 118 48 17 17 17 N N N N N N HOXC6 high in NP −6.4 0.013759973 −1.9 14022 34 42 23 5 2 10 N N N N N N PAIP2 high in NP −4.3 0.013753154 −1.9 14023 358 804 240 109 70 72 N N N N N N SMAD1 high in NP −3.3 0.013746335 −1.9 14024 165 142 92 38 35 28 N N N N N N SLFN11 high in NP −5.7 0.013721105 −1.9 14025 100 141 42 15 10 18 N N N N N N LARP4 high in NP −3.7 0.013710876 −1.9 14026 36 103 64 22 20 20 N N N N N N SLC25A5 high in NP −5.0 0.013704057 −1.9 14027 521 1408 1509 191 274 236 N N N N N N UBAC1 high in NP −30.2 0.013663144 −1.9 14028 13 68 47 6 6 6 N N N N N P PGM1 high in NP −4.9 0.013650869 −1.9 14029 63 145 150 28 28 17 N N N N N N ANXA3 high in NP −33.6 0.013624275 −1.9 14030 17 59 87 11 11 11 N N N N N N GNG11 high in NP −12.2 0.013591544 −1.9 14031 114 136 80 29 8 3 N N N N N N PABPC1 high in NP −9.3 0.013584726 −1.9 14032 491 2907 2340 219 257 279 N N N N N N GIMAP1 high in NP −3.8 0.013564269 −1.9 14033 14 3 4 2 2 2 N N N N N N USMG5 high in NP −12.3 0.01355745 −1.9 14034 70 573 437 25 32 12 N N N N N N UBE2E2 high in NP −4.3 0.013540402 −1.9 14035 304 204 121 69 23 23 N N N N P N FAF2 high in NP −4.2 0.013533583 −1.9 14036 47 122 91 29 18 15 N N N N N N H2AFX high in NP −3.4 0.013526764 −1.9 14037 178 245 378 53 63 75 N N N N N N BCL6B high in NP −2.8 0.01351449 −1.9 14038 18 15 16 6 6 6 N N N N N N CFL1 high in NP −3.7 0.013466076 −1.9 14039 6197 7615 6422 1768 2567 1265 N N N N N N CHST14 high in NP −3.5 0.013411524 −1.9 14040 70 56 40 11 12 7 N N N N N N ANP32B high in NP −3.8 0.013369247 −1.9 14041 252 457 469 137 101 98 N N N N N N ZFP36L1 high in NP −7.7 0.01334879 −1.9 14042 10556 7441 2836 1317 413 1470 N N N N N N PC high in NP −4.9 0.013336516 −1.9 14043 29 38 42 17 13 13 N N N N N N SOD1 high in NP −9.4 0.013322878 −1.9 14044 115 697 556 54 40 50 N N N N N N DBC1 high in NP −5.7 0.01330924 −1.9 14045 44 46 36 12 19 12 P N N N N N COL12A1 high in NP −3.7 0.013259461 −1.9 14046 135 343 276 50 46 83 N N N N N N REST high in NP −6.0 0.013236959 −1.9 14047 98 46 75 14 10 25 N N N N N N CBX8 high in NP −4.0 0.013213774 −1.9 14048 21 23 26 7 8 5 P P N N P N LOC728640 high in NP −55.9 0.013206955 −1.9 14049 7 86 81 1 1 1 NA NA N N N N EEF1B2 high in NP −3.4 0.013172861 −1.9 14050 83 119 99 31 18 22 N N N N N N SPIN1 high in NP −3.9 0.013159223 −1.9 14051 207 187 159 77 38 51 N N N N P N C2CD2 high in NP −3.7 0.013137402 −1.9 14052 124 270 175 65 51 34 N N N N N N TRMT112 high in NP −7.0 0.013124446 −1.9 14053 147 810 474 81 60 23 NA NA N N N N TRPT1 high in NP −4.8 0.013110808 −1.9 14054 25 49 63 10 7 4 N N N N N N CYP51A1 high in NP −5.8 0.013084896 −1.9 14055 128 444 310 74 38 28 N N N N N N GNS high in NP −4.1 0.013067849 −1.9 14056 644 865 439 217 73 161 N N N N N N MPDU1 high in NP −5.3 0.01306103 −1.9 14057 21 60 26 3 6 3 N N N N N N ATP6AP2 high in NP −5.7 0.013040573 −1.9 14058 119 142 67 35 9 9 N N N N N N UBQLN2 high in NP −3.2 0.013020116 −1.9 14059 284 443 328 119 100 79 N P N N N N C13orf15 high in NP −6.5 0.013006478 −1.9 14060 36 467 63 9 8 8 N N N N N N C17orf95 high in NP −7.9 0.012972383 −1.9 14061 19 51 50 9 3 3 N N N N N N KCNH6 high in NP −9.2 0.012965564 −1.9 14062 116 492 872 52 20 46 N N N N N N PDE4A high in NP −4.8 0.012915786 −1.9 14063 118 113 50 22 13 19 P P N N N N THBS4 high in NP −8.8 0.012908967 −1.9 14064 1860 407 130 38 40 38 P P N N P N ARF4 high in NP −2.9 0.012883055 −1.9 14065 1164 2043 1164 399 418 445 N N N N N N IER2 high in NP −3.1 0.012872826 −1.9 14066 4844 4819 5864 1356 1990 1543 N N N N N N RNF166 high in NP −8.5 0.012853733 −1.9 14067 41 35 25 3 3 12 N N N N N N RPS27L high in NP −4.5 0.012829185 −1.9 14068 332 470 430 164 73 61 N N N N N N EIF4H high in NP −3.5 0.012822366 −1.9 14069 2014 4235 3090 927 963 785 N N N N N N TAGLN2 high in NP −5.5 0.012815547 −1.9 14070 666 2439 1584 387 279 261 N N N N N N MFAP3 high in NP −4.6 0.012801909 −1.9 14071 410 218 209 87 55 39 N N N N N N SMAD4 high in NP −3.4 0.012751449 −1.9 14072 86 134 137 56 33 25 N N N N N N DBI high in NP −7.7 0.012724173 −1.9 14073 81 298 299 26 23 30 N N N N N N GIMAP6 high in NP −3.5 0.012717354 −1.9 14074 34 37 19 12 12 12 N N N N N N SFRP2 high in NP −6.4 0.012710535 −1.9 14075 613 157 71 19 15 17 P N N N N N CANX high in NP −5.2 0.012646437 −1.9 14076 1909 2894 2716 1178 547 421 N N N N N N ARHGEF7 high in NP −4.8 0.012632799 −1.9 14077 151 385 344 73 63 69 N N N N N N FAM102A high in NP −3.2 0.01262598 −1.9 14078 993 699 744 224 242 331 N N N N N N NDUFAF1 high in NP −8.0 0.012599386 −1.9 14079 15 33 20 4 7 4 N N N N N N DCX high in NP −6.8 0.012585748 −1.9 14080 508 77 123 14 14 28 N N N N N N SLC2A4RG high in NP −4.0 0.01257211 −1.9 14081 183 92 98 18 26 29 N N N N N N ZNF773 high in NP −6.2 0.012565292 −1.9 14082 12 20 21 3 1 1 N N N N N N GPX7 high in NP −5.4 0.012544835 −1.9 14083 57 61 33 17 8 8 N N N N N N MFN2 high in NP −7.7 0.012505285 −1.9 14084 49 193 160 29 28 25 N N N N N N SLC2A1 high in NP −4.4 0.012484146 −1.9 14085 1314 1254 2322 450 491 247 N N N N N N CHN1 high in NP −5.9 0.012418002 −1.9 14086 30 79 57 14 4 4 N N N N N N ITPA high in NP −14.7 0.012411183 −1.9 14087 21 174 116 8 4 4 N N N N N N ELOVL5 high in NP −3.6 0.01239209 −1.9 14088 757 1647 1317 231 217 408 N N N N N N GMPR high in NP −4.6 0.01235254 −1.9 14089 19 30 22 6 6 3 N N N N N N NIPSNAP1 high in NP −6.4 0.012323219 −1.9 14090 91 40 36 10 9 4 N N N N N N WDR25 high in NP −4.2 0.012288442 −1.9 14091 40 23 27 8 7 4 N N N N N N CD46 high in NP −6.8 0.012281623 −1.9 14092 117 372 403 53 45 45 N N N N N N ARID5B high in NP −6.8 0.012233208 −1.9 14093 308 1593 1647 138 97 266 N N N N N N LOC139201 high in NP −8.7 0.012226389 −1.9 14094 12 22 31 1 4 1 NA NA N N N N SFRP4 high in NP −5.3 0.01221957 −1.9 14095 7279 2348 1578 674 404 394 N N N N N N C19orf43 high in NP −3.2 0.012212751 −1.9 14096 1346 1279 1530 320 413 483 N N N N N N STT3A high in NP −6.3 0.012199114 −1.9 14097 192 272 271 92 37 27 N N N N P N DNAJC14 high in NP −5.0 0.012178657 −1.9 14098 33 108 71 10 10 13 N N N N N N IGFBP2 high in NP −5.4 0.012171838 −1.9 14099 546 434 234 112 74 40 N N N N N N APP high in NP −3.1 0.012117968 −1.9 14100 2685 2995 3185 829 1181 899 N N N N N N RSU1 high in NP −3.9 0.012111149 −1.9 14101 221 161 119 39 48 24 N N N N N N C11orf60 high in NP −3.2 0.01210433 −1.9 14102 NA NA NA NA NA NA N N N N N N RPL32 high in NP −5.1 0.011986362 −1.9 14103 6867 16324 16728 1996 2473 3092 N N N N P N RARB high in NP −3.6 0.011979543 −1.9 14104 37 96 49 14 12 9 N N N N N N PCDHB5 high in NP −3.3 0.011965905 −1.9 14105 14 15 11 2 2 2 N N N N N N DKK3 high in NP −5.7 0.011959086 −1.9 14106 59 533 106 17 22 17 N N N N N N CPNE3 high in NP −3.8 0.011952267 −1.9 14107 95 107 62 17 29 15 N N N N N N PIK3R2 high in NP −3.7 0.01193181 −1.9 14108 69 52 63 13 18 18 N N N N N N GOLGA4 high in NP −3.2 0.011918173 −1.9 14109 49 93 77 27 27 30 N N N N N N COPB2 high in NP −5.3 0.011856802 −1.9 14110 85 188 265 45 27 21 N N N N N N AKR1C3 high in NP −5.5 0.011824071 −1.9 14111 479 644 1148 218 95 40 N N N N N N FAM10A4 high in NP −38.1 0.011803614 −1.9 14112 27 528 503 9 4 6 N N N N N N TRIM52 high in NP −7.9 0.011796795 −1.9 14113 280 939 1080 106 108 102 N N N N N N C5orf32 high in NP −3.6 0.011783157 −1.9 14114 405 659 662 183 157 143 N N N N N N RRAS2 high in NP −10.0 0.0117627 −1.9 14115 59 373 220 23 24 21 N N N N N N PGCP high in NP −8.7 0.011742243 −1.9 14116 68 135 27 6 6 13 N N N N N N RAB40B high in NP −5.9 0.011735424 −1.9 14117 64 82 88 8 23 14 N N N N N N MAPK1IP1L high in NP −2.8 0.011712922 −1.9 14118 280 374 390 131 154 118 N N N N N N CTNND1 high in NP −5.4 0.011706103 −1.9 14119 208 495 581 68 111 82 N N N N N N DDAH1 high in NP −4.7 0.011689056 −1.9 14120 309 186 103 35 31 22 N N N N N N HNRNPAB high in NP −8.9 0.011682237 −1.9 14121 348 2505 1517 123 157 146 N N N N N N SH2B3 high in NP −5.0 0.011675418 −1.9 14122 865 566 336 194 81 81 N N N N N N ZNF669 high in NP −3.8 0.011668599 −1.9 14123 71 100 62 9 16 15 N N N N N N TMED2 high in NP −4.9 0.011629731 −1.9 14124 773 2213 1733 449 325 194 N N N N N N INSR high in NP −4.1 0.011616093 −1.9 14125 63 193 166 46 34 32 N N N N N P CHRNE high in NP −5.8 0.011581998 −1.9 14126 73 34 29 11 6 6 N N N N N N SNRPD2 high in NP −7.5 0.011548585 −1.9 14127 236 932 819 115 74 60 N N N N N N HP1BP3 high in NP −3.2 0.011483805 −1.9 14128 622 637 678 215 199 282 N N N N N N NAALADL2 high in NP −2.8 0.011476986 −1.9 14129 21 22 21 10 10 10 N N N N N N CS high in NP −2.9 0.011463348 −1.9 14130 992 1179 900 450 405 353 N N N N P N TBCB high in NP −5.6 0.01144971 −1.9 14131 37 163 78 13 11 6 N N N N N N MED28 high in NP −12.2 0.011418343 −1.9 14132 27 165 148 6 8 13 N N N N N N NR2F2 high in NP −8.9 0.011411524 −1.9 14133 1866 898 554 353 32 94 N N N N N N CDCA4 high in NP −4.7 0.011404705 −1.9 14134 72 40 48 18 9 13 N N N N N N TMEM173 high in NP −7.9 0.011397886 −1.9 14135 41 57 9 4 4 4 N N N N N N RBM24 high in NP −3.6 0.011362428 −1.9 14136 28 34 26 8 8 6 N P N N P N B3GALNT1 high in NP −3.7 0.011341971 −1.9 14137 18 22 22 6 6 6 N N N N N P YBX1 high in NP −40.2 0.011321514 −1.9 14138 69 1383 1243 29 26 21 N N N N P N DDIT4 high in NP −4.9 0.011189908 −2.0 14139 224 52 44 6 9 10 N N N N N N DNAJB9 high in NP −9.2 0.011115581 −2.0 14140 95 633 394 40 19 37 N N N N N N GLUL high in NP −5.6 0.011101943 −2.0 14141 401 1383 868 181 139 216 N N N N N N FLJ36031 high in NP −4.4 0.011095124 −2.0 14142 94 403 72 15 19 17 N N N N N N PPFIBP1 high in NP −4.4 0.01107194 −2.0 14143 137 360 161 38 59 39 N N N N N N UGDH high in NP −18.4 0.011051483 −2.0 14144 193 3085 1322 79 69 76 N N N N N N NCL high in NP −4.3 0.011024207 −2.0 14145 651 1635 676 169 236 236 N N N N N N PFKFB3 high in NP −4.0 0.011010569 −2.0 14146 1852 2138 1264 344 411 611 N N N N N N ABHD14B high in NP −6.2 0.010996931 −2.0 14147 432 164 158 43 24 48 N N N N N N AK3 high in NP −4.1 0.010950563 −2.0 14148 208 153 115 51 25 34 N N N N N N PCOLCE high in NP −6.0 0.010931469 −2.0 14149 189 523 203 27 28 73 N N N N N N DDB1 high in NP −4.8 0.010911013 −2.0 14150 449 924 974 222 174 92 N N N N N N SF3B14 high in NP −8.0 0.010895329 −2.0 14151 108 361 408 25 39 36 N N N N N N CMBL high in NP −3.4 0.010872826 −2.0 14152 19 14 23 8 8 8 N N N N N N FXYD1 high in NP −6.9 0.010866008 −2.0 14153 45 144 31 6 4 10 N N N N N N PSME1 high in NP −4.0 0.010859189 −2.0 14154 918 778 638 304 144 145 N N N N N N RPL31 high in NP −7.4 0.010845551 −2.0 14155 1549 5906 6703 410 701 670 N N N N N N EIF3D high in NP −3.5 0.010831913 −2.0 14156 669 859 1159 281 277 190 N N N N N N FGF13 high in NP −4.2 0.010803273 −2.0 14157 28 9 14 6 6 6 N P N N N N ARL1 high in NP −5.5 0.010772588 −2.0 14158 152 149 109 46 23 12 N N N N N N DFNA5 high in NP −5.6 0.010720082 −2.0 14159 75 6 7 3 3 3 N N N N N N REEP5 high in NP −8.4 0.010706444 −2.0 14160 198 997 760 61 82 89 N N N N N N NCBP2 high in NP −7.0 0.010674395 −2.0 14161 73 369 203 26 26 16 N N N N N N AGRN high in NP −4.7 0.010660757 −2.0 14162 117 167 238 26 55 29 N N N N N N FBN1 high in NP −4.3 0.010631435 −2.0 14163 487 358 366 78 71 133 N N N N N N PUM2 high in NP −3.9 0.010624616 −2.0 14164 193 308 357 56 67 97 N N N N N N TMC7 high in NP −3.6 0.010617797 −2.0 14165 97 222 153 37 27 30 N P N N N N HK2 high in NP −6.5 0.010576202 −2.0 14166 292 847 1054 107 179 114 N P N N P N SET high in NP −3.5 0.010555745 −2.0 14167 1054 1595 1521 407 490 471 N N N N N N TBC1D2B high in NP −3.2 0.010516195 −2.0 14168 259 228 238 71 50 83 N N N N N N SGK1 high in NP −10.1 0.010503921 −2.0 14169 190 1156 895 58 84 79 N N N N N N CSNK1A1 high in NP −3.5 0.01042073 −2.0 14170 663 637 656 226 314 205 N N N N N N PAM high in NP −4.6 0.010389362 −2.0 14171 116 313 267 58 32 33 N N N N N N HSD17B11 high in NP −6.6 0.010333447 −2.0 14172 426 398 137 60 27 52 N N N N N N ETS2 high in NP −5.1 0.010326628 −2.0 14173 420 1548 468 185 83 100 N N N N N N RBBP7 high in NP −5.5 0.01031299 −2.0 14174 98 189 281 30 30 34 N N N N N N DOPEY2 high in NP −4.4 0.010287078 −2.0 14175 218 413 496 85 45 86 N N N N N N C15orf44 high in NP −6.1 0.010267985 −2.0 14176 46 134 140 21 17 9 N N N N N N RRBP1 high in NP −3.4 0.010248892 −2.0 14177 144 166 213 42 36 53 N N N N N N NADSYN1 high in NP −5.6 0.010242073 −2.0 14178 23 40 36 12 12 12 N N N N N N PPP2R2A high in NP −12.5 0.010228435 −2.0 14179 59 456 325 19 24 24 N N N N N N PPP1R14A high in NP −9.2 0.010150699 −2.0 14180 123 31 12 6 6 6 N N N N N N DDOST high in NP −12.0 0.010138425 −2.0 14181 45 332 222 23 10 7 N N N N N N UBE2NL high in NP −39.2 0.010088646 −2.0 14182 72 1269 56 1 8 9 N N N N N N PVRL4 high in NP −6.2 0.010081827 −2.0 14183 59 74 133 12 25 12 P N N N N N RPL26 high in NP −28.0 0.01006819 −2.0 14184 378 6791 4171 123 133 155 N N N N N N HBB high in NP −142.1 0.010018411 −2.0 14185 378 193410 14939 181 82 70 N N N N N N LARGE high in NP −3.6 0.010006137 −2.0 14186 61 118 67 20 17 17 N N N N N N HSD3B7 high in NP −5.0 0.009999318 −2.0 14187 183 391 108 39 35 28 N N N N N N ADCY3 high in NP −4.3 0.009972042 −2.0 14188 156 535 213 61 46 39 N N N N N N TRMT5 high in NP −39.7 0.009927037 −2.0 14189 36 960 947 10 10 21 N N N N N N TJP2 high in NP −5.9 0.009920218 −2.0 14190 61 144 161 27 21 22 N N N N N N ADAMTS4 high in NP −6.8 0.009913399 −2.0 14191 4978 23897 2598 795 542 762 N N N N N N B4GALT5 high in NP −4.7 0.009874531 −2.0 14192 367 1034 587 130 134 172 N N N N N N CXCL14 high in NP −10.2 0.009800886 −2.0 14193 461 1855 187 32 77 73 N N N N P N TSC22D2 high in NP −5.4 0.009759973 −2.0 14194 310 448 196 34 49 88 N N N N N N ATF1 high in NP −3.9 0.009732697 −2.0 14195 89 67 101 18 21 9 N N N N N N MOBKL2A high in NP −6.5 0.00971224 −2.0 14196 156 482 275 59 49 17 N N N N N N EGLN3 high in NP −4.8 0.009626321 −2.0 14197 49 49 87 9 6 14 N N N N N N MTDH high in NP −5.5 0.009612683 −2.0 14198 114 495 224 54 58 42 N N N N N N SLC2A14 high in NP −17.4 0.009605864 −2.0 14199 336 74 85 14 2 13 P N N N N N CAMK2N1 high in NP −8.5 0.009566314 −2.0 14200 140 428 233 44 17 47 N N N N N N SERPINH1 high in NP −4.4 0.009559495 −2.0 14201 5457 6708 4077 1167 715 1627 N N N N N N SERPINF2 high in NP −3.0 0.009524719 −2.0 14202 25 18 16 7 7 7 N N N N N N GADD45A high in NP −20.5 0.009498807 −2.0 14203 64 727 407 10 20 27 N N N N N N CSRP2 high in NP −13.3 0.009491988 −2.0 14204 16 93 43 5 5 5 N N N N N P YES1 high in NP −2.9 0.009450392 −2.0 14205 277 247 262 90 110 88 N N N N N N F3 high in NP −13.4 0.009443573 −2.0 14206 63 396 300 22 30 21 N N N N N N C4orf3 high in NP −3.6 0.009401296 −2.0 14207 1260 1013 949 389 295 163 NA NA N N N N ANO7 high in NP −4.0 0.009394477 −2.0 14208 111 174 199 31 36 28 N N N N N N LRRN4CL high in NP −4.0 0.009346062 −2.0 14209 47 75 55 9 14 12 N N N N N N CDYL high in NP −4.1 0.009332424 −2.0 14210 62 111 78 23 14 12 N N N N N N CCDC47 high in NP −3.8 0.009318786 −2.0 14211 345 737 380 104 138 106 N N N N N N TSPAN6 high in NP −4.9 0.00930583 −2.0 14212 21 42 46 7 5 5 N P N N N N TES high in NP −7.3 0.009293556 −2.0 14213 594 1410 1183 155 352 92 N N N N N N SALL2 high in NP −4.6 0.009243778 −2.0 14214 62 38 48 11 11 6 N P N N N N AR high in NP −5.5 0.00922673 −2.0 14215 94 40 33 11 10 7 N N N N N N TANC1 high in NP −4.3 0.009213092 −2.0 14216 105 204 154 34 44 35 N N P N N N HIBADH high in NP −4.8 0.009166723 −2.0 14217 130 39 27 9 9 6 N N N N N N RAB7A high in NP −6.3 0.009159905 −2.0 14218 1174 3607 2499 429 529 380 P N N N N N ABLIM1 high in NP −4.6 0.009121718 −2.0 14219 208 341 177 61 74 42 N N N N N N NR3C1 high in NP −3.5 0.00910808 −2.0 14220 165 201 156 52 31 56 N N N N N N CHGA high in NP −3.8 0.009066485 −2.0 14221 14 4 5 2 2 2 N N N N N N PHF23 high in NP −6.6 0.009046028 −2.0 14222 57 160 160 18 17 21 N N N N N N TMEM64 high in NP −6.4 0.009039209 −2.0 14223 288 780 392 65 63 136 N N N N N N MAP2K4 high in NP −12.4 0.009023525 −2.0 14224 26 110 131 7 8 8 N N N N N N EPAS1 high in NP −8.3 0.009016706 −2.0 14225 2124 3770 796 495 265 200 N N N N N N BRD7P3 high in NP −12.4 0.009009887 −2.0 14226 25 148 62 4 11 4 N N N N N N C4orf34 high in NP −3.1 0.008982612 −2.0 14227 21 16 11 4 4 4 N N N N N N RPL15 high in NP −6.1 0.008923287 −2.0 14228 1898 6251 4413 804 704 777 N N N N N N DPYSL2 high in NP −4.3 0.008896011 −2.1 14229 693 656 470 191 59 163 N N N N N N SLC35B2 high in NP −6.4 0.00885987 −2.1 14230 98 183 232 21 8 33 N N N N N N FKBP1A high in NP −7.6 0.008825776 −2.1 14231 647 2942 2492 382 168 173 N P N N N N C9orf16 high in NP −6.6 0.008785544 −2.1 14232 97 148 133 15 31 10 N N N N N N RPS29 high in NP −57.7 0.00874463 −2.1 14233 192 7469 5361 32 44 96 N N N N N N NME7 high in NP −5.7 0.008730992 −2.1 14234 56 60 58 15 9 7 N N N N N N RPS8 high in NP −14.4 0.008683259 −2.1 14235 591 3818 4459 143 232 256 N N N N N N ATP1B1 high in NP −18.7 0.008668258 −2.1 14236 56 387 474 17 25 20 N N N N N N RAB8B high in NP −8.5 0.008661439 −2.1 14237 107 397 420 46 19 39 N N N N N N AZIN1 high in NP −8.7 0.008613706 −2.1 14238 171 665 552 65 59 52 N N N N N N COX5B high in NP −6.9 0.008598023 −2.1 14239 51 225 67 14 7 7 N N N N N N PSMA6 high in NP −5.3 0.008509376 −2.1 14240 238 613 634 112 42 38 N N N N N N CYB5B high in NP −4.5 0.0084821 −2.1 14241 126 196 150 39 41 16 N N N N N N PROP high in NP −4.7 0.008454824 −2.1 14242 113 85 78 22 17 10 N N N N N N HDAC11 high in NP −5.2 0.008425503 −2.1 14243 74 42 40 14 8 8 N N N N N N FAM96A high in NP −8.4 0.008418684 −2.1 14244 14 27 36 3 3 3 N N N N N N CLIC1 high in NP −5.1 0.008398227 −2.1 14245 562 1275 1142 229 212 205 N N N N N N ZFYVE9 high in NP −4.2 0.00836345 −2.1 14246 50 39 36 16 13 16 N N N N N N RPL13AP5 high in NP −3.8 0.008349812 −2.1 14247 236 429 315 64 67 65 NA NA N N N N GNAI3 high in NP −11.4 0.008322537 −2.1 14248 98 360 368 35 31 27 N N N N N N ARSB high in NP −3.9 0.008295261 −2.1 14249 83 146 73 22 20 17 N N N N N N PJA2 high in NP −3.6 0.008288442 −2.1 14250 344 300 300 112 65 73 N N N N N N USP33 high in NP −4.6 0.008274804 −2.1 14251 83 198 156 40 22 25 N N N N N N RPL10A high in NP −3.9 0.008252983 −2.1 14252 9210 8776 13610 1809 2581 2461 N N N N N N TRIP10 high in NP −3.8 0.008218889 −2.1 14253 148 204 169 26 43 35 N N N N N N LPPR2 high in NP −3.3 0.00821207 −2.1 14254 428 377 491 131 116 119 N N N N N N CPZ high in NP −8.9 0.008205251 −2.1 14255 475 184 70 14 16 8 P N N N N N NEK7 high in NP −3.9 0.008198432 −2.1 14256 206 294 307 66 64 72 N N N N N N ZFP91 high in NP −3.6 0.008171156 −2.1 14257 779 889 849 318 149 276 N N N N N N IL6 high in NP −8.9 0.008164337 −2.1 14258 47342 37086 11728 3886 2766 3724 N N N N N N RCAN1 high in NP −5.9 0.008148653 −2.1 14259 46 210 86 17 15 18 N N N N N N RRP7A high in NP −10.6 0.008141834 −2.1 14260 23 110 43 7 2 2 N N N N N N PSAP high in NP −4.2 0.008135015 −2.1 14261 1010 2332 1722 423 278 404 N N N N N N CBFB high in NP −5.0 0.008121377 −2.1 14262 241 601 369 69 58 84 N N N N N N SHQ1 high in NP −5.4 0.00810774 −2.1 14263 25 42 40 7 7 7 N N N N N N RPL27 high in NP −14.1 0.008066826 −2.1 14264 461 3529 2353 155 140 146 N N N N N N KIAA0247 high in NP −6.4 0.008060007 −2.1 14265 1542 1082 579 322 197 124 N N N N N N TBC1D20 high in NP −5.2 0.00803955 −2.1 14266 316 615 622 143 99 107 N N N N N N CD8B high in NP −5.9 0.008032731 −2.1 14267 72 29 18 6 6 6 N N N N N N HCFC1 high in NP −3.1 0.008019093 −2.1 14268 338 415 424 139 126 138 N N N N N N CHP high in NP −4.3 0.008012274 −2.1 14269 1113 1027 633 229 220 199 N N N N N N RBPJ high in NP −6.5 0.007982953 −2.1 14270 50 183 68 18 16 16 N N N N N N GPM6B high in NP −5.2 0.007976134 −2.1 14271 113 154 175 42 29 18 N N N N N N SCAND1 high in NP −5.3 0.007955677 −2.1 14272 141 220 289 41 40 19 N N N N N N CNKSR3 high in NP −7.3 0.007948858 −2.1 14273 39 107 66 13 14 14 N N N N N N LRP12 high in NP −9.0 0.007942039 −2.1 14274 33 135 69 12 12 15 N N N N N N BACE2 high in NP −6.8 0.007916127 −2.1 14275 38 90 112 10 15 10 N N N N N N HOXD8 high in NP −7.4 0.007902489 −2.1 14276 29 59 32 2 2 8 N N N N N N NUPR1 high in NP −3.5 0.00789567 −2.1 14277 497 569 643 193 141 133 N N N N N N ARF3 high in NP −4.4 0.007869758 −2.1 14278 1107 795 821 285 252 138 N N N N N N GABARAPL2 high in NP −5.1 0.007837027 −2.1 14279 69 124 117 13 21 9 N N N N N N SPIN4 high in NP −4.1 0.00781657 −2.1 14280 25 31 27 7 7 7 N P N N N N PIK3IP1 high in NP −5.6 0.007809751 −2.1 14281 59 119 84 18 13 14 N N N N N N SS18 high in NP −4.5 0.007789294 −2.1 14282 288 428 480 126 57 63 N N N N N N TRAPPC3 high in NP −6.8 0.007762018 −2.1 14283 81 132 188 23 14 5 N N N N N N SERPING1 high in NP −4.2 0.007727924 −2.1 14284 214 522 191 47 44 50 N N N N N N ARL5B high in NP −6.4 0.007721105 −2.1 14285 134 93 83 9 9 22 N N N N N N NGRN high in NP −16.1 0.007707467 −2.1 14286 43 297 264 12 14 9 N N N N N N C16orf42 high in NP −4.9 0.007700648 −2.1 14287 70 157 148 22 15 10 N N N N N N STOM high in NP −5.9 0.00768701 −2.1 14288 13672 6612 3593 1315 817 937 N N N N N N NDRG1 high in NP −5.2 0.007660416 −2.1 14289 4859 3253 4736 876 422 1070 N N N N N N CD2AP high in NP −4.8 0.007643369 −2.1 14290 44 75 69 19 19 17 N N N N N N UBAC2 high in NP −4.6 0.00763655 −2.1 14291 33 19 30 10 10 10 N N N N N N TNN high in NP −4.8 0.007584726 −2.1 14292 529 430 395 29 78 110 N N N N N N IGFBP4 high in NP −4.4 0.007533583 −2.1 14293 1613 2106 1570 415 267 557 N N N N N N SLC15A4 high in NP −4.2 0.007526764 −2.1 14294 70 116 81 23 21 13 N N N N N N ETV5 high in NP −4.8 0.007511763 −2.1 14295 152 149 245 35 25 49 N N N N N P CHMP2B high in NP −9.1 0.007504944 −2.1 14296 53 254 240 10 10 21 N N N N N N SCOC high in NP −4.6 0.007460621 −2.1 14297 28 36 66 6 6 6 N N N N N N FN1 high in NP −8.0 0.007446983 −2.1 14298 1397 2181 568 93 168 226 N N N N N N TMEM66 high in NP −17.8 0.007440164 −2.1 14299 79 698 346 14 8 27 N N N N N N SLC27A1 high in NP −4.0 0.007406069 −2.1 14300 155 147 161 37 37 17 N N N N N N CCDC82 high in NP −6.3 0.007390385 −2.1 14301 23 71 45 7 7 7 N N N N P N ELL high in NP −4.9 0.007383566 −2.1 14302 939 1042 1023 196 210 364 N N N N N N PI16 high in NP −10.0 0.007369928 −2.1 14303 452 903 234 14 39 82 N N N N N N ISG15 high in NP −8.3 0.007363109 −2.1 14304 305 57 122 14 10 8 N N N N N N FBXO7 high in NP −16.8 0.007349472 −2.1 14305 43 259 223 17 13 10 N N N N P N C8orf58 high in NP −4.3 0.007329697 −2.1 14306 18 16 15 7 7 7 N N N N N N EIF6 high in NP −9.5 0.007322878 −2.1 14307 194 759 741 69 66 31 N N N N N N LILRB3 high in NP −11.4 0.007316059 −2.1 14308 76 359 269 22 18 8 N N N N N N CMPK1 high in NP −6.4 0.007246505 −2.1 14309 385 896 589 142 116 44 N N N N N N COLEC12 high in NP −4.4 0.007226048 −2.1 14310 37 72 76 9 9 13 N N N N N N NCOA4 high in NP −3.9 0.007198773 −2.1 14311 499 553 398 133 140 92 N N N N N N VASP high in NP −12.0 0.007183089 −2.1 14312 114 423 180 33 40 21 N N N N N N RBM14 high in NP −5.9 0.00717627 −2.1 14313 172 527 341 68 52 57 N N N N N N SF1 high in NP −4.5 0.007152404 −2.1 14314 2366 4624 3661 776 1102 993 N N N N N N CCNI high in NP −11.6 0.007145585 −2.1 14315 271 2899 854 93 33 65 N N N N N N C10orf116 high in NP −6.5 0.007131947 −2.1 14316 788 906 374 59 119 105 N N N N N N CHSY1 high in NP −4.1 0.007118309 −2.1 14317 1292 1106 782 311 269 352 N N N N N N LRRC61 high in NP −8.5 0.00711149 −2.1 14318 54 28 32 2 5 8 N N N N P N EIF3H high in NP −4.6 0.007104671 −2.1 14319 387 646 870 86 130 119 N N N N N N MXRA7 high in NP −5.2 0.007082168 −2.1 14320 1185 1265 582 278 210 205 N N N N N N FAM150B high in NP −4.1 0.007075349 −2.2 14321 14 11 12 3 3 3 N P N N N N CHMP5 high in NP −17.5 0.007048074 −2.2 14322 88 364 425 22 5 18 N N N N N N KCNMB4 high in NP −15.4 0.007020798 −2.2 14323 99 9 20 5 2 2 N N N N N N SPTLC1 high in NP −7.1 0.007013979 −2.2 14324 49 119 137 17 17 15 P N P N N N YIPF5 high in NP −4.1 0.006993522 −2.2 14325 118 166 148 38 28 32 N N N N N N PRPF31 high in NP −6.6 0.006966246 −2.2 14326 27 85 55 8 8 6 N N N N N N KIAA1715 high in NP −3.4 0.006945789 −2.2 14327 144 133 140 43 34 29 N N N N N N SC4MOL high in NP −13.5 0.006932151 −2.2 14328 112 656 587 45 30 16 N N N N N N MXRA5 high in NP −6.8 0.006906239 −2.2 14329 490 177 165 33 27 48 N N N N N N SPARCL1 high in NP −7.2 0.006858507 −2.2 14330 281 1115 184 39 42 33 N N N N N N C22orf13 high in NP −5.3 0.006843505 −2.2 14331 448 643 567 187 98 78 N N N N N N CDK9 high in NP −3.2 0.006788953 −2.2 14332 482 580 570 164 171 173 N N N N N N FUS high in NP −13.0 0.006782134 −2.2 14333 309 1898 1354 138 74 82 N N N N N N OLFML2A high in NP −7.3 0.006768496 −2.2 14334 419 340 148 25 22 49 N N N N N N GPAA1 high in NP −4.2 0.006728265 −2.2 14335 216 161 206 51 35 36 N N N N N N LOC552889 high in NP −3.8 0.006721446 −2.2 14336 NA NA NA NA NA NA N N N N N N MYO1B high in NP −4.0 0.006709171 −2.2 14337 207 258 304 86 67 59 N N N N N N CCL2 high in NP −7.6 0.006695534 −2.2 14338 6445 2848 1112 366 385 244 N N N N N N CDIPT high in NP −6.5 0.006668258 −2.2 14339 169 295 283 56 12 31 N N N N N N PIN1 high in NP −4.8 0.006661439 −2.2 14340 142 93 105 26 12 15 N N N N N N HES1 high in NP −8.0 0.006642346 −2.2 14341 215 338 447 84 23 35 N N N N N N PRSS23 high in NP −7.0 0.006563928 −2.2 14342 193 291 102 36 15 18 N N N N N N TGIF2 high in NP −8.2 0.006543471 −2.2 14343 1156 604 330 60 51 127 N N N N N N SPP1 high in NP −3.7 0.006536652 −2.2 14344 37 49 57 11 14 11 N N N N N N GEM high in NP −12.3 0.006529833 −2.2 14345 433 1496 1034 38 71 207 N N N N N N FBXL20 high in NP −4.2 0.006461643 −2.2 14346 27 32 23 8 6 6 N N N P N N FEN1 high in NP −8.5 0.006454824 −2.2 14347 22 62 65 6 6 6 N N N N N N ID4 high in NP −11.4 0.006434368 −2.2 14348 58 542 119 17 15 15 N N N N N N PTPRS high in NP −5.6 0.00642073 −2.2 14349 817 374 551 116 62 116 N N N N N N THBS1 high in NP −9.4 0.006398227 −2.2 14350 1332 3715 4223 136 534 440 N N N N N N TMEM50A high in NP −4.2 0.006383225 −2.2 14351 69 93 94 24 14 17 N N N N N N LOC653566 high in NP −32.0 0.006362768 −2.2 14352 48 397 451 9 1 9 NA NA N N N N CLDND1 high in NP −3.6 0.006342312 −2.2 14353 875 841 774 195 217 251 N N N N N N PPP2CA high in NP −4.5 0.006308217 −2.2 14354 542 957 926 165 192 205 N N N N N N RPL10 high in NP −3.8 0.006301398 −2.2 14355 25828 21030 26439 4688 6158 5983 N N N N P N CAPN6 high in NP −8.0 0.006294579 −2.2 14356 333 66 79 8 8 14 P P N N N N HIF1A high in NP −6.2 0.00628776 −2.2 14357 1200 1311 746 331 135 117 N N N N N N TMEM11 high in NP −41.4 0.006268667 −2.2 14358 15 131 63 4 4 4 N N N N N N CYBA high in NP −3.8 0.00624821 −2.2 14359 176 225 210 44 51 36 N N N N N N KCTD9 high in NP −16.6 0.006234572 −2.2 14360 124 654 725 28 22 40 N N N N N N MGAT4B high in NP −4.7 0.006220934 −2.2 14361 235 327 438 82 60 59 N N N N N N RAP2A high in NP −6.0 0.006200477 −2.2 14362 137 243 243 40 15 39 N N N N N N DUSP16 high in NP −6.8 0.006186839 −2.2 14363 20 51 52 4 4 4 N N N N N N PKIG high in NP −6.5 0.00618002 −2.2 14364 1246 792 687 246 86 105 N N N N N N TMEM106B high in NP −4.5 0.006152745 −2.2 14365 79 124 177 24 19 20 N N N N N N MBNL2 high in NP −5.8 0.006139107 −2.2 14366 268 544 258 46 49 83 N N N N N N YIF1A high in NP −7.8 0.006117286 −2.2 14367 297 198 268 54 25 9 N P N N N N USP22 high in NP −4.9 0.006103648 −2.2 14368 757 1575 1297 330 227 242 N N N N N N YAP1 high in NP −7.1 0.006091374 −2.2 14369 298 1016 679 118 87 97 N N N N N N OLFML3 high in NP −7.2 0.006077054 −2.2 14370 159 179 55 10 10 22 N N N N N N COL14A1 high in NP −6.2 0.006070235 −2.2 14371 1086 437 260 47 67 71 N N N N N N PLAT high in NP −5.0 0.006063416 −2.2 14372 110 387 149 32 23 25 N N N N N N LATS2 high in NP −7.4 0.006034095 −2.2 14373 444 1053 1673 111 141 163 N N N N N N PSMA2 high in NP −13.1 0.006013638 −2.2 14374 166 746 719 49 42 32 N N N N N N STK10 high in NP −4.1 0.005986362 −2.2 14375 115 196 203 34 45 36 N N N N N N NCRNA00188 high in NP −68.7 0.00593181 −2.2 14376 125 3915 2656 33 24 33 NA NA N N N N SFRS9 high in NP −13.7 0.005863621 −2.2 14377 287 1266 1442 86 83 63 N N N N N N SNAPC3 high in NP −5.1 0.005853392 −2.2 14378 55 42 96 13 12 9 N N N N N N MAP2K3 high in NP −5.4 0.005839755 −2.2 14379 3194 4138 3236 360 1009 606 N N N N N N TPT1 high in NP −26.0 0.005819298 −2.2 14380 615 6782 4709 116 161 217 N N N N N N C6orf62 high in NP −8.7 0.00580566 −2.2 14381 262 856 626 92 50 68 N N N N N N RNF130 high in NP −9.3 0.005798841 −2.2 14382 48 104 64 10 6 11 N N N N N N SLC39A7 high in NP −6.9 0.005792022 −2.2 14383 152 399 278 53 35 18 N N N N N N RPL35 high in NP −5.6 0.005785203 −2.2 14384 4546 7634 9373 1123 1453 1034 N N N N N N OTUD1 high in NP −9.4 0.005778384 −2.2 14385 82 385 153 16 9 23 NA NA N N N N AZGP1 high in NP −19.2 0.005771565 −2.2 14386 65 238 444 20 30 18 P P N N N N DCAKD high in NP −6.8 0.005751108 −2.2 14387 59 55 32 7 12 10 N N N N N N NAMPT high in NP −10.4 0.005744289 −2.2 14388 359 1604 980 144 86 72 N N N N N N TRA2B high in NP −5.8 0.005730651 −2.2 14389 151 257 313 56 30 34 NA NA N N N N HABP4 high in NP −4.3 0.005723832 −2.2 14390 44 49 34 10 8 11 N N N N N N GYPC high in NP −8.9 0.005682919 −2.2 14391 544 522 285 101 37 27 N N N N N N ATXN10 high in NP −8.4 0.005669281 −2.2 14392 65 189 190 19 14 10 N N N N N N LAPTM4B high in NP −11.7 0.005662462 −2.2 14393 142 595 525 46 38 38 N N N N N N ARAF high in NP −4.0 0.005643369 −2.2 14394 39 74 56 15 13 13 N N N N N N MRC2 high in NP −9.0 0.005610638 −2.3 14395 1897 1494 979 70 133 322 N N N N N N SH3KBP1 high in NP −5.9 0.005603819 −2.3 14396 156 117 168 35 13 11 N N N N N N RPL27A high in NP −58.0 0.005597 −2.3 14397 252 6766 5664 46 49 92 N N N N N N C14orf1 high in NP −5.1 0.005590181 −2.3 14398 35 21 37 6 4 4 N N N N N N SPTBN1 high in NP −5.3 0.005583362 −2.3 14399 996 574 533 189 106 143 N N N N N N TM9SF3 high in NP −6.1 0.005576543 −2.3 14400 538 1128 1217 223 188 107 N N N N P N ELK3 high in NP −4.4 0.005569724 −2.3 14401 110 115 78 20 20 12 N N N N N N AP1AR high in NP −7.0 0.00552881 −2.3 14402 75 175 196 17 18 26 NA NA N N N N PPME1 high in NP −6.5 0.005463348 −2.3 14403 112 202 346 40 27 28 N N N N N N NAB2 high in NP −5.0 0.005456529 −2.3 14404 125 76 68 11 14 14 N N N N P N LOXL2 high in NP −8.6 0.005436072 −2.3 14405 357 311 421 103 28 32 N N N N N N STC1 high in NP −8.3 0.00541016 −2.3 14406 6046 894 733 174 117 89 P P N N N N LGMN high in NP −4.4 0.005396522 −2.3 14407 290 471 366 75 54 88 N N N N N N SUB1 high in NP −7.7 0.005382884 −2.3 14408 113 281 238 41 23 13 N N N N N N PPP1CB high in NP −5.0 0.005367201 −2.3 14409 698 1411 979 287 247 188 N N N N N N STAU1 high in NP −5.0 0.005318786 −2.3 14410 169 267 256 34 56 44 N N N N N N C14orf129 high in NP −7.9 0.005279918 −2.3 14411 23 23 18 6 6 9 N N N N N N YPEL2 high in NP −6.1 0.005273099 −2.3 14412 381 612 366 91 36 92 N N N N N N CD44 high in NP −4.4 0.005239004 −2.3 14413 5212 9345 5153 1493 1191 1330 N N N N N N TNPO2 high in NP −4.3 0.005196045 −2.3 14414 391 382 477 109 75 116 N N N N N N GPR124 high in NP −6.6 0.005168769 −2.3 14415 369 164 104 17 19 22 N N N N N N LAPTM4A high in NP −6.9 0.005155131 −2.3 14416 5692 9698 4858 1531 613 762 N N N N N N RPS18 high in NP −15.2 0.005148312 −2.3 14417 4106 21524 17358 795 1250 1049 N N N N N N DYRK1A high in NP −4.5 0.005127855 −2.3 14418 452 894 653 172 152 136 N N N N N N TMEM8B high in NP −4.9 0.005121036 −2.3 14419 43 58 37 9 9 13 NA NA N N N N MARCKSL1 high in NP −4.7 0.00510058 −2.3 14420 435 526 440 64 117 94 N N N N N N CXor38 high in NP −3.8 0.005031708 −2.3 14421 14 6 6 3 3 3 N N N N N N INSIG1 high in NP −7.3 0.004990794 −2.3 14422 344 214 245 30 27 69 N N N N N N IRF2BP2 high in NP −7.0 0.004983975 −2.3 14423 532 1543 1120 130 108 227 N N N N N N CCS high in NP −4.1 0.0049567 −2.3 14424 31 18 19 5 5 5 N N N N N N CTSK high in NP −5.9 0.004936243 −2.3 14425 37 101 42 8 8 6 N N N N N N DYNLRB1 high in NP −8.2 0.004915786 −2.3 14426 173 357 265 47 23 10 N N N N N N ETV6 high in NP −6.4 0.004908967 −2.3 14427 252 242 241 41 72 38 N N N N N N ARF6 high in NP −9.6 0.004881691 −2.3 14428 976 3467 2706 165 279 331 N N N N N N PCDH18 high in NP −6.1 0.004868053 −2.3 14429 207 149 248 23 20 45 N N N N N N C3orf58 high in NP −3.7 0.004840777 −2.3 14430 57 70 67 15 18 13 N N N N N N MRPL44 high in NP −19.6 0.004808046 −2.3 14431 140 773 835 27 20 34 N N N N N N GPNMB high in NP −7.9 0.004801227 −2.3 14432 1330 1214 583 63 134 162 N N N N N N DLK1 high in NP −6.9 0.004773952 −2.3 14433 32 53 69 5 8 5 N N N N N N VEGFB high in NP −7.0 0.004760314 −2.3 14434 404 250 239 68 30 27 N N N N N N CLEC11A high in NP −8.2 0.004739857 −2.3 14435 81 68 26 5 10 5 N N N N N N RNF19B high in NP −5.6 0.0047194 −2.3 14436 171 322 266 29 47 43 N N N N N N FBLN7 high in NP −4.8 0.004705762 −2.3 14437 105 79 84 21 11 14 N N N N N N C19orf56 high in NP −7.8 0.004666212 −2.3 14438 254 722 511 74 47 54 N N N N N N HNRNPUL1 high in NP −12.6 0.004659393 −2.3 14439 172 785 558 44 27 47 N N N N P N LOXL3 high in NP −9.8 0.004645755 −2.3 14440 73 37 34 10 6 6 N N N N N N PCDHB14 high in NP −8.8 0.004638936 −2.3 14441 26 26 13 5 5 8 N N N N N N TPM3 high in NP −3.6 0.004618479 −2.3 14442 907 1029 794 303 255 289 N N N N N N H3F3C high in NP −12.7 0.00461166 −2.3 14443 322 1555 959 97 44 51 NA NA N N N N MFGE8 high in NP −4.3 0.004577566 −2.3 14444 2411 2004 2087 536 582 417 N N N N N N PHLDA3 high in NP −8.6 0.004570747 −2.3 14445 28 98 64 7 7 7 N N N N N N FBXO21 high in NP −4.5 0.004543471 −2.3 14446 136 218 181 42 29 29 N N N N N N CAMLG high in NP −10.6 0.004529833 −2.3 14447 58 184 285 11 14 14 N N N N N N H1FX high in NP −16.9 0.004523014 −2.3 14448 549 1309 2068 199 27 56 N N N N N N ZC3H11A high in NP −7.3 0.004516195 −2.3 14449 224 565 446 78 40 52 N N N N N N C14orf147 high in NP −16.2 0.004488919 −2.3 14450 284 1313 1364 61 73 79 N N N N N N LOC154761 high in NP −8.6 0.0044821 −2.3 14451 83 28 50 6 9 6 N N N N N N HHAT high in NP −4.9 0.004468462 −2.3 14452 31 21 15 9 9 9 N N N N N N CCPG1 high in NP −4.5 0.004461643 −2.4 14453 82 79 89 21 19 25 N N N N N N CCDC53 high in NP −9.6 0.004448005 −2.4 14454 45 59 29 7 3 3 N N N N P N PGF high in NP −4.3 0.004441186 −2.4 14455 49 63 51 15 13 16 N N N N N N CTDSP1 high in NP −6.3 0.004411865 −2.4 14456 1205 890 567 188 75 77 N N N N N N ST8SIA2 high in NP −10.3 0.004370951 −2.4 14457 73 117 39 17 19 17 P P N N N N GBE1 high in NP −10.9 0.004364132 −2.4 14458 53 156 175 18 15 12 N N P N N N CSRNP2 high in NP −8.2 0.004357313 −2.4 14459 101 320 141 24 16 24 NA NA N N N N DYRK3 high in NP −8.8 0.004343675 −2.4 14460 33 146 40 7 7 7 N N N N N N AKIRIN1 high in NP −4.2 0.004323219 −2.4 14461 463 427 354 101 86 99 N N N N N N TMED9 high in NP −5.3 0.004304125 −2.4 14462 33 50 36 9 6 6 N N N N N N C1orf55 high in NP −11.3 0.004290488 −2.4 14463 192 1257 427 44 41 40 N N N N N N PHC2 high in NP −5.8 0.004283669 −2.4 14464 1407 2009 1359 431 256 183 N N N N N N MRPL24 high in NP −6.3 0.004256393 −2.4 14465 81 102 125 13 14 5 N N N N N N PLP1 high in NP −6.3 0.004246164 −2.4 14466 60 31 50 8 8 8 P N N N N N MXRA8 high in NP −11.1 0.004218889 −2.4 14467 2351 992 1337 59 100 273 N N N N N N PFN2 high in NP −4.6 0.004184794 −2.4 14468 311 365 395 99 58 56 N N N N P N GNAI2 high in NP −6.6 0.004171156 −2.4 14469 1154 824 446 157 78 122 N N N N N N BMP3 high in NP −10.6 0.004152063 −2.4 14470 52 192 158 8 11 11 P P N N N N MRPS11 high in NP −7.9 0.004145244 −2.4 14471 20 21 29 4 7 4 N N N N N N TMEM185A high in NP −6.8 0.00413297 −2.4 14472 138 134 109 32 20 16 P P N N N N LUC7L2 high in NP −4.7 0.004098875 −2.4 14473 239 344 333 73 66 60 N N N N N N C10orf32 high in NP −4.8 0.004085237 −2.4 14474 95 135 113 26 15 17 N N N N N N DAP high in NP −15.3 0.004071599 −2.4 14475 96 588 272 21 9 9 N N N N N N ARL4D high in NP −6.5 0.004051142 −2.4 14476 96 116 65 9 3 11 N N N N N N SLC38A5 high in NP −20.4 0.004044323 −2.4 14477 99 376 626 16 24 17 N N N N N N STOML2 high in NP −7.7 0.003989772 −2.4 14478 296 671 664 90 44 32 N N N N N N CDC42 high in NP −4.6 0.003982953 −2.4 14479 1502 1911 1939 592 436 370 N N N N N N PHLPP1 high in NP −7.5 0.003976134 −2.4 14480 103 227 204 27 29 20 NA NA N N N N DUSP6 high in NP −9.6 0.003969315 −2.4 14481 224 571 630 59 56 47 N N N N N N C7orf50 high in NP −7.6 0.003948858 −2.4 14482 51 35 45 8 4 4 N N P N N N TMEM176B high in NP −7.7 0.003914081 −2.4 14483 523 482 236 39 48 54 N N N N N N GTF2H5 high in NP −6.1 0.003907262 −2.4 14484 158 307 199 53 30 35 N N N N P N C2or76 high in NP −9.0 0.003893624 −2.4 14485 13 15 11 2 2 2 N N N N N N EID1 high in NP −7.0 0.003886805 −2.4 14486 315 473 344 47 16 56 N N N N N N PPP1CA high in NP −21.9 0.003864985 −2.4 14487 56 340 398 18 9 9 P N N N N N RPLP2 high in NP −10.8 0.003851347 −2.4 14488 10732 34769 28806 2330 2613 2517 N N N N N N IMPDH2 high in NP −8.1 0.003844528 −2.4 14489 229 530 597 47 54 53 N N N N N N APH1A high in NP −8.3 0.003817252 −2.4 14490 281 668 834 74 65 44 N N N N N N KDM5B high in NP −7.2 0.003810433 −2.4 14491 44 75 81 18 18 18 NA NA N N N N CHST15 high in NP −7.2 0.003803614 −2.4 14492 698 895 787 121 88 212 NA NA N N N N MMGT1 high in NP −10.0 0.003776338 −2.4 14493 77 250 159 22 13 13 NA NA N N N N PMAIP1 high in NP −25.2 0.0037627 −2.4 14494 34 162 171 6 9 6 P P N N N N ELF1 high in NP −7.0 0.003755881 −2.4 14495 294 436 316 43 27 71 N N N N N N FAH high in NP −5.0 0.003742243 −2.4 14496 57 47 68 12 12 9 N N N N N N RAB32 high in NP −22.5 0.003728606 −2.4 14497 43 218 265 11 10 7 N N N N N N SLC7A3 high in NP −12.8 0.00366178 −2.4 14498 86 20 8 4 4 4 N P N N N N WDR33 high in NP −7.8 0.003654961 −2.4 14499 140 330 401 46 48 51 N N N N N N IGFBP3 high in NP −4.6 0.003641323 −2.4 14500 309 337 279 88 58 58 N N N N N N HEBP1 high in NP −6.5 0.003605182 −2.4 14501 24 58 47 3 3 3 N N N N N N KDELR2 high in NP −7.2 0.003586089 −2.4 14502 1015 2478 1834 367 208 194 N N N N N N ORAI3 high in NP −6.3 0.003558814 −2.4 14503 78 76 48 13 9 6 N N N N N N ALKBH7 high in NP −5.3 0.003545176 −2.5 14504 264 183 271 37 37 37 N N N N N N SAR1A high in NP −7.6 0.003538357 −2.5 14505 411 1104 762 120 64 98 N N N N N N RPS27 high in NP −10.6 0.003510399 −2.5 14506 10291 32526 25541 1523 1776 2899 N N N N N N GLT8D2 high in NP −23.2 0.003496761 −2.5 14507 117 181 118 6 6 22 N N N N N N C7orf55 high in NP −10.6 0.003489942 −2.5 14508 20 44 36 6 4 4 NA NA N N N N HADH high in NP −5.7 0.003476304 −2.5 14509 105 76 154 18 16 17 N N N N N N GNB2L1 high in NP −8.6 0.003469485 −2.5 14510 2477 6443 6171 623 618 684 N N N N N N MARCKS high in NP −8.8 0.003408115 −2.5 14511 4872 3429 2529 789 216 404 N N N N N N KCNA6 high in NP −5.0 0.003380839 2.5 14512 21 18 31 5 5 5 P N N N N N RNF138P1 high in NP −6.3 0.003324241 −2.5 14513 60 159 82 13 9 12 N N N N N N BBS9 high in NP −6.3 0.003310603 −2.5 14514 18 12 13 6 6 6 N N N N N N SDCBP high in NP −6.7 0.003243096 −2.5 14515 1011 2122 2036 283 202 266 N N N N N N RPL11 high in NP −9.1 0.003236277 −2.5 14516 4755 9919 12311 937 1017 1290 N N N N N N TP53 high in NP −8.7 0.003229458 −2.5 14517 106 202 180 22 24 12 N N N N N N COL1A1 high in NP −40.5 0.003196045 −2.5 14518 19342 4514 2059 61 183 422 N N N N N N GLT25D1 high in NP −6.7 0.003168769 −2.5 14519 149 328 293 45 37 36 N N N N N N LDHA high in NP −14.6 0.003155131 −2.5 14520 901 4676 2750 179 240 132 N N N N N N LOC93622 high in NP −6.9 0.003134674 −2.5 14521 132 256 184 21 13 28 NA NA N N N N MFAP2 high in NP −6.1 0.003121036 −2.5 14522 45 28 47 4 4 4 N N N N N N EIF2S3 high in NP −9.0 0.003086942 −2.5 14523 359 856 798 101 90 72 N N N N N N HSPC159 high in NP −6.1 0.003025571 −2.5 14524 27 50 26 6 6 6 N N N N N N ACAT1 high in NP −6.6 0.003018752 −2.5 14525 54 118 71 11 10 7 N N N N N N KHSRP high in NP −12.3 0.003011933 −2.5 14526 417 1834 1182 77 98 82 N N N N N N CUTA high in NP −5.3 0.002991476 −2.5 14527 455 482 664 75 103 80 N N N N N N MSX1 high in NP −12.1 0.0029642 −2.5 14528 1505 1619 869 61 100 209 P N N N N P SH3BGRL high in NP −8.8 0.002957382 −2.5 14529 105 236 91 10 15 16 N N N N N N MMP14 high in NP −6.6 0.002950563 −2.5 14530 490 272 318 72 38 41 N N N N N N EIF3K high in NP −7.6 0.002916468 −2.5 14531 407 853 826 88 83 90 N N N N N N LGALS3BP high in NP −9.6 0.002909649 −2.5 14532 179 316 107 29 32 28 N N N N N N RPL13 high in NP −5.8 0.00285987 −2.5 14533 13811 27322 19338 2730 2989 3131 N N N N P N ITPRIPL2 high in NP −10.1 0.002803273 −2.6 14534 402 1321 772 116 83 83 N N N N N N TGFBI high in NP −7.7 0.002780771 −2.6 14535 673 858 392 66 43 100 N N N N N N PYGO2 high in NP −4.5 0.002746676 −2.6 14536 109 107 125 26 20 21 N N N N N N YWHAH high in NP −5.9 0.0027194 −2.6 14537 620 1120 999 129 173 98 N N N N N N TBL1XR1 high in NP −5.6 0.002705762 −2.6 14538 439 378 296 73 63 88 N N N N N N PTPLAD2 high in NP −9.2 0.002652574 −2.6 14539 19 44 28 3 3 3 N N N N N N RAB13 high in NP −13.1 0.002613024 −2.6 14540 131 436 360 28 6 12 N N N N N N IL28RA high in NP −9.3 0.002599386 −2.6 14541 26 36 51 10 10 10 N N N N N N TMEM59 high in NP −4.2 0.002592567 −2.6 14542 2296 2116 2083 530 464 494 N N N N N N GALT high in NP −8.0 0.002558473 −2.6 14543 46 47 23 12 12 13 N N N N N N VAPA high in NP −5.5 0.002551654 −2.6 14544 372 530 557 100 104 86 N N N N N N EEF1A1 high in NP −10.7 0.002515513 −2.6 14545 405 1066 1126 86 52 98 N N N N N N DULLARD high in NP −8.1 0.002488237 −2.6 14546 153 310 225 33 16 21 N N N N N N DCN high in NP −16.3 0.002474599 −2.6 14547 2533 15623 4229 288 269 501 N N N N N N ANKRD10 high in NP −7.6 0.002461643 −2.6 14548 308 432 598 75 35 58 N N N N N N PCBP1 high in NP −31.4 0.002454824 −2.6 14549 365 2451 2638 59 46 64 N N N N N N GABARAP high in NP −25.7 0.002434368 −2.6 14550 161 989 1046 35 14 18 N N N N N N RPSAP58 high in NP −11.4 0.002415274 −2.6 14551 3040 9770 7188 454 552 725 NA NA N N N N RPL37 high in NP −25.7 0.002392772 −2.6 14552 1487 9047 8412 132 256 294 N N N N N N PPP6C high in NP −15.3 0.002358677 −2.6 14553 191 702 617 44 40 23 N N N N N N DLC1 high in NP −6.4 0.002331401 −2.6 14554 100 152 145 23 23 26 N N P N N N RAC1 high in NP −5.3 0.002324582 −2.6 14555 2983 3756 2825 669 558 391 N N N N N N PUM1 high in NP −5.3 0.00230208 −2.6 14556 211 285 316 63 65 59 N N N N N N FGFR1OP2 high in NP −8.1 0.002288442 −2.6 14557 64 100 130 7 7 13 N N N N N N CD9 high in NP −46.3 0.002207296 −2.7 14558 112 1072 681 16 13 11 N N N N N N CSTF1 high in NP −16.5 0.002166383 −2.7 14559 27 42 68 6 8 6 N N N N N N HEPH high in NP −9.7 0.002152745 −2.7 14560 141 57 49 18 18 18 N N N N N N PPP1CC high in NP −9.4 0.002139107 −2.7 14561 357 787 458 39 73 52 N N N N N N TMSB10 high in NP −17.9 0.002125469 −2.7 14562 1375 5031 5667 142 280 239 N N N N P N CD164 high in NP −9.3 0.002106376 −2.7 14563 203 382 412 42 30 35 N N N N N N GJA1 high in NP −9.0 0.002085919 −2.7 14564 4604 4973 6353 280 535 828 N N N N N N TMEM9 high in NP −6.6 0.002051824 −2.7 14565 46 64 68 7 7 7 N N N N N N CCNG1 high in NP −13.4 0.002038186 −2.7 14566 70 182 178 9 12 6 N N N N N N ISCU high in NP −10.2 0.002017729 −2.7 14567 103 211 273 15 15 15 N N N N P N VKORC1 high in NP −12.8 0.00201091 −2.7 14568 72 269 92 9 5 5 N N N N N N CDK2AP1 high in NP −9.4 0.001956359 −2.7 14569 696 1067 1112 157 103 49 N N N N N N COL3A1 high in NP −71.2 0.001935902 −2.7 14570 49181 3991 3601 55 155 254 N N N N N N EPHB4 high in NP −4.7 0.001873849 −2.7 14571 136 158 133 28 28 25 N N N N N N SCP2 high in NP −5.4 0.001860211 −2.7 14572 58 57 61 11 14 11 N N N N N N PPT2 high in NP −8.6 0.001832936 −2.7 14573 46 71 33 10 10 10 N N N N N N VEZT high in NP −9.5 0.001826117 −2.7 14574 88 207 179 13 14 14 N N N N N N SEMA3G high in NP −5.4 0.00180566 −2.7 14575 135 108 128 22 20 18 N N N N N N LUM high in NP −38.6 0.001785203 −2.7 14576 604 9203 1447 31 20 68 N N N N N N TUBA1A high in NP −13.9 0.001771565 −2.8 14577 329 1079 846 21 59 30 N N N N N N C17orf106 high in NP −6.9 0.001764746 −2.8 14578 25 35 39 4 4 4 NA NA N N N N COL1A2 high in NP −16.5 0.00172656 −2.8 14579 14735 3963 2750 265 162 391 N N N N N N PAPSS1 high in NP −9.9 0.001719741 −2.8 14580 149 105 82 14 15 9 N N N N N N ATPIF1 high in NP −13.4 0.001692465 −2.8 14581 71 193 163 13 11 11 N N N N N N HSP90AB1 high in NP −14.9 0.001672008 −2.8 14582 7016 20056 18444 771 1175 1102 N N N N N N LASP1 high in NP −12.5 0.00165837 −2.8 14583 357 558 341 27 17 52 N N N N N N P4HA2 high in NP −11.7 0.001651551 −2.8 14584 33 56 71 7 7 7 N N N N N N KDELR1 high in NP −7.1 0.001603819 −2.8 14585 1036 1838 1303 256 181 171 N N N N N N TIMP2 high in NP −12.3 0.001569724 −2.8 14586 5246 8059 2692 249 230 553 N N N N N N HSPA2 high in NP −29.4 0.00152881 −2.8 14587 59 126 69 12 8 8 N N N N N N MYL9 high in NP −21.2 0.001481077 −2.8 14588 735 1281 298 26 51 18 N N N N N N RBM3 high in NP −15.7 0.001467439 −2.8 14589 462 1306 1466 80 76 37 N N N N N N AP2A1 high in NP −8.7 0.001453802 −2.8 14590 143 334 254 30 16 13 N N N N N N BMS1P5 high in NP −18.8 0.001433345 −2.8 14591 27 41 72 3 1 1 N N N N N N PLSCR4 high in NP −8.5 0.001406069 −2.9 14592 124 206 209 19 19 22 N N N N N N NCSTN high in NP −13.4 0.001392431 −2.9 14593 132 334 122 15 9 15 N N N N N N RPL7 high in NP −30.6 0.001385612 −2.9 14594 1545 8408 8184 141 231 201 N N N N N N LGALS1 high in NP −10.3 0.001365155 −2.9 14595 2501 2584 1259 231 160 222 N N N N N N PVRL2 high in NP −9.9 0.001281282 −2.9 14596 892 447 787 75 87 58 N N N N P N FOS high in NP −17.8 0.001260825 −2.9 14597 2439 8583 9563 192 298 556 N N N N N N PTGS2 high in NP −13.9 0.001254006 −2.9 14598 760 1829 2139 61 61 153 N N N N N N SPARC high in NP −16.8 0.001219911 −2.9 14599 7437 8035 2291 376 343 462 N N N N N N GOLPH3 high in NP −8.0 0.001213092 −2.9 14600 783 908 820 171 76 102 N N N N N N IGFBP6 high in NP −6.6 0.001185817 −2.9 14601 624 589 455 83 56 80 N N N N N N C19orf40 high in NP −6.4 0.001138084 −2.9 14602 446 495 509 84 49 61 N N N N N N C3orf14 high in NP −8.8 0.001124446 −2.9 14603 19 13 28 3 3 3 N N N N P N PTP4A2 high in NP −14.0 0.001117627 −3.0 14604 715 2541 1707 118 93 112 N N N N N N MRPS33 high in NP −11.1 0.001083532 −3.0 14605 23 49 33 2 2 2 N P N N N N ZDHHC1 high in NP −6.5 0.001049437 −3.0 14606 64 49 65 9 7 7 N N N N P N VCL high in NP −7.8 0.0010358 −3.0 14607 1484 1251 927 154 186 128 N N N N P N NDUFB4 high in NP −40.5 0.001015343 −3.0 14608 172 678 872 19 9 5 N N N N N N SCARA5 high in NP −7.8 0.001008524 −3.0 14609 168 274 160 21 14 20 N N N N N N INS-IGF2 high in NP −24.8 0.000994886 −3.0 14610 1220 562 534 14 14 57 N N N N N N ITPKB high in NP −7.3 0.000919877 −3.0 14611 135 236 173 24 18 21 N N N N N N CPE high in NP −12.7 0.000913058 −3.0 14612 475 846 357 42 26 52 N N N N N N NPC2 high in NP −7.7 0.000872145 −3.1 14613 685 901 669 65 101 101 N N N N N N PNRC1 high in NP −21.8 0.000858507 −3.1 14614 1377 4940 4447 226 91 188 N N N N N N POSTN high in NP −8.3 0.000778043 −3.1 14615 147 249 139 19 19 19 N N N N N N COL6A1 high in NP −9.7 0.000771224 −3.1 14616 1969 3021 1328 268 184 222 N N N N N N CENPH high in NP −13.8 0.000737129 −3.1 14617 119 289 215 10 10 5 N N N N N N LY96 high in NP −12.4 0.000723491 −3.1 14618 59 18 12 2 2 2 N N N N N N LOC649330 high in NP −7.1 0.000682578 −3.2 14619 268 370 291 31 27 35 NA NA N N N N PPP1R15A high in NP −14.3 0.000675759 −3.2 14620 798 2037 1813 86 115 137 N N N N N N RCN2 high in NP −25.1 0.000613706 −3.2 14621 62 167 135 12 9 9 N N N N N N ERO1L high in NP −20.6 0.000568701 −3.2 14622 254 698 701 32 23 16 N N N N N N TMEM14C high in NP −23.9 0.000555063 −3.3 14623 95 303 159 8 5 5 N N N N N N COX8A high in NP −11.1 0.000534606 −3.3 14624 592 1150 1065 89 68 69 P N N N N N EEF1G high in NP −22.0 0.000520968 −3.3 14625 4404 12125 13529 351 565 447 N N N N N N XPNPEP2 high in NP −7.7 0.000458234 −3.3 14626 27 29 26 6 6 6 N N N N N N RPS20 high in NP −14.8 0.000437777 −3.4 14627 2467 7995 3850 234 281 250 N N N N N N C5orf13 high in NP −15.9 0.000430958 −3.4 14628 541 174 183 9 9 9 N N N N P N TCN2 high in NP −26.6 0.000390044 −3.4 14629 76 51 45 9 9 13 N N N N N N HNRNPA0 high in NP −10.6 0.000369587 −3.4 14630 1350 2790 1614 180 140 169 N N N N N N SCARB2 high in NP −11.1 0.000330038 −3.5 14631 307 523 360 37 23 26 N N N N N N C11orf10 high in NP −13.6 0.0003164 −3.5 14632 1250 1290 1456 138 85 68 N N N N N N CDKN1B high in NP −14.6 0.000295943 −3.5 14633 148 158 164 10 8 14 N N N N N N SEPP1 high in NP −18.3 0.00024821 −3.6 14634 471 524 572 11 21 28 N N N N N N HMGCL high in NP −16.8 0.000200477 −3.7 14635 35 16 25 3 3 3 N N N P N N LRRC41 high in NP −14.9 0.000186839 −3.7 14636 1046 2170 1490 90 102 68 N N N N N N ALKBH5 high in NP −28.8 0.000167064 −3.8 14637 934 2589 2079 93 53 48 N N N N N N CUL4B high in NP −16.8 0.000153427 −3.8 14638 117 123 85 17 15 15 N N N N N N SEP2 high in NP −27.3 0.000146608 −3.8 14639 1162 1330 1283 93 44 39 NA NA N N N N ITM2A high in NP −50.4 0.000139789 −3.9 14640 1640 3240 2971 27 35 102 N N N N N N LITAF high in NP −17.1 0.000126151 −3.9 14641 1397 3139 1979 107 115 119 N N N N N N ACTG1 high in NP −22.7 0.000112513 −3.9 14642 16540 18348 12824 607 948 494 N N N N N N KLK3 high in NP −28.6 7.16E−05 −4.1 14643 50 43 51 3 3 3 P P N N N N SS18L2 high in P 28.4 7.84E−05 4.1 1 127 108 170 3241 3173 4378 N N N N N N PUS7L high in P 22.1 8.52E−05 4.1 2 7 7 7 24 32 35 N N N N N N INTS12 high in P 15.9 9.21E−05 4.0 3 23 18 15 278 357 220 N N N N N N CCT2 high in P 16.1 9.89E−05 4.0 4 905 888 1060 14970 19937 15800 N N N N N N CECR6 high in P 16.7 0.000105694 4.0 5 7 7 8 24 23 35 N N N N N N LEAP2 high in P 12.6 0.000119332 3.9 6 1 1 1 14 14 18 N N N N N N NME2P1 high in P 24.0 0.000160245 3.8 7 2 2 3 48 69 77 N N N N N N QRSL1 high in P 22.9 0.000173883 3.8 8 44 25 46 648 939 700 N N N N N N RAB39 high in P 18.8 0.000207296 3.7 9 2 2 3 27 29 15 N N N N N N PRICKLE3 high in P 14.7 0.000214115 3.7 10 7 17 23 241 316 388 N N N N N N AIPL1 high in P 20.5 0.000220934 3.7 11 9 2 3 54 47 43 P P N N N N ZNF93 high in P 21.1 0.000227753 3.6 12 4 7 6 106 70 136 N N N N N N HPVC1 high in P 11.1 0.000234572 3.6 13 2 2 3 14 14 18 N N N N N N MAP1S high in P 16.1 0.000241391 3.6 14 277 158 375 4509 5657 4396 N N N N N N LRRC10 high in P 13.5 0.000255029 3.6 15 5 5 5 16 27 20 N N N N N N ACTR5 high in P 19.0 0.000261848 3.6 16 16 32 43 649 698 502 P P N N N N CCDC13 high in P 14.3 0.000268667 3.6 17 2 2 2 16 25 13 N N N P N N C12orf59 high in P 20.5 0.000275486 3.6 18 11 5 6 40 50 61 P N P N N N RGPD1 high in P 23.9 0.000282305 3.5 19 5 7 5 131 162 111 N N N N N N ZNF692 high in P 17.0 0.000289124 3.5 20 37 17 34 433 479 618 N N N N N N DCXR high in P 29.4 0.000302762 3.5 21 87 92 268 3532 4763 2673 N N N N N N GPATCH2 high in P 17.9 0.000323219 3.5 22 10 15 18 111 219 225 N N N N N N C15orf48 high in P 43.5 0.000336856 3.5 23 14 9 3 151 295 230 N N N N N N POLR3E high in P 11.8 0.000349131 3.5 24 28 47 57 367 557 610 N N N N N N PPP4R1L high in P 19.9 0.00035595 3.4 25 4 4 4 36 27 27 N N N N N N PRO0628 high in P 28.4 0.000362768 3.4 26 9 2 4 76 65 110 N N N N N N ZNF619 high in P 26.7 0.000376406 3.4 27 NA NA NA NA NA NA N N N N N N ACCN3 high in P 19.3 0.000383225 3.4 28 7 8 18 171 258 323 N N N N N N MESTIT1 high in P 18.8 0.000396863 3.4 29 20 9 20 266 215 408 N N N N N N C5orf60 high in P 12.2 0.000403682 3.4 30 2 2 3 32 14 15 NA NA N N N N PTPN23 high in P 21.8 0.000410501 3.4 31 197 112 294 4663 4370 2429 N N N N N N SLC45A4 high in P 14.2 0.000424139 3.4 32 19 25 25 224 311 262 N N N N N N BCL2L12 high in P 14.2 0.000444596 3.4 33 31 27 54 391 380 416 N N N N N N MAGI2 high in P 10.2 0.000451415 3.3 34 32 32 46 266 224 300 N N N N N N XRCC6 high in P 11.2 0.000465053 3.3 35 1742 1343 2659 21489 22306 18279 N N N N N N SMURF1 high in P 18.4 0.000471872 3.3 36 303 101 394 5495 6799 5795 N N N N P N KRBA1 high in P 22.9 0.000478691 3.3 37 16 20 33 405 554 205 N N N N N N KCNK3 high in P 14.8 0.00048551 3.3 38 9 13 11 256 94 69 P P N N N N RINT1 high in P 16.2 0.000492329 3.3 39 23 13 27 321 235 152 N N N N N N C21orf88 high in P 8.6 0.000499148 3.3 40 99 77 99 665 728 848 NA NA N N N N SLC16A13 high in P 12.3 0.000514149 3.3 41 1 1 1 12 17 9 N N N N N N CFP high in P 12.5 0.000527787 3.3 42 24 9 9 147 113 175 N N N N N N ANAPC1 high in P 14.9 0.000541425 3.3 43 70 25 48 663 682 702 N N N N N N RMND5B high in P 16.5 0.000548244 3.3 44 47 20 26 733 511 296 N N N N N N GPR37L1 high in P 15.2 0.000561882 3.3 45 14 9 22 147 228 289 N N N N N N LOC493754 high in P 15.1 0.00057552 3.2 46 370 202 458 3476 4487 6672 N N N N N N ZNF836 high in P 14.0 0.000582339 3.2 47 2 2 4 56 34 36 N N N N N N CD101 high in P 43.6 0.000589158 3.2 48 7 7 9 50 208 240 NA NA N N N N PLAC8L1 high in P 15.3 0.000620525 3.2 49 1 1 1 16 19 28 N N N N N N SKA1 high in P 7.5 0.000627344 3.2 50 3 3 3 9 10 14 NA NA N N N N METTL2B high in P 29.8 0.000634163 3.2 51 2 2 4 42 61 39 N N N N N N CASP8 high in P 11.7 0.000640982 3.2 52 39 28 42 287 462 510 N N N N N N ADRB3 high in P 8.0 0.000647801 3.2 53 29 30 25 198 157 211 P N N N N N NASP high in P 11.8 0.00065462 3.2 54 148 184 330 1941 2047 2985 N N N N N N FAM83E high in P 14.4 0.00066894 3.2 55 41 14 37 349 376 493 N N N N N N RAGE high in P 15.9 0.000689397 3.2 56 15 20 30 240 299 281 N N N N N N SDR39U1 high in P 10.3 0.000696215 3.2 57 228 207 364 2331 1969 2789 NA NA N N N N SNORA21 high in P 19.4 0.000703034 3.2 58 1 1 2 22 27 33 N N N N N N TIMM17B high in P 9.2 0.000709853 3.1 59 39 30 50 453 346 261 N N N N N N ZSCAN20 high in P 9.3 0.000716672 3.1 60 3 3 4 13 17 11 N N N N N N TSEN54 high in P 14.0 0.00073031 3.1 61 48 22 45 337 576 384 N N N N N N HPDL high in P 52.9 0.000743948 3.1 62 1 1 6 118 205 65 N N N N N N DPH3B high in P 7.4 0.000750767 3.1 63 2 3 3 18 25 15 NA NA N N N N MTERFD2 high in P 7.0 0.000764405 3.1 64 16 24 19 203 116 121 N N N N N N LOC642313 high in P 20.5 0.000784862 3.1 65 9 3 5 46 48 70 NA NA N N N N BCAN high in P 15.8 0.000791681 3.1 66 22 8 23 245 180 312 P N N N N N FCER1G high in P 38.4 0.0007985 3.1 67 2 2 2 74 12 45 N N N N N N PECR high in P 26.1 0.000805319 3.1 68 2 2 4 52 29 45 N N N N N N C17orf67 high in P 27.3 0.000812138 3.1 69 13 2 9 146 136 224 N N N N N N C9orf45 high in P 14.7 0.000818957 3.1 70 6 6 7 18 22 61 NA NA N N N N ZNF33A high in P 12.5 0.000825776 3.1 71 13 16 20 123 220 118 N N N N N N LRWD1 high in P 9.2 0.000832595 3.1 72 11 20 17 158 160 113 N N N N N N COX18 high in P 20.8 0.000839414 3.1 73 21 11 13 183 164 210 N N N N P N ZNF767 high in P 14.8 0.000865326 3.1 74 28 14 34 272 331 276 N N N N N N ATP6V1B1 high in P 13.8 0.000878964 3.1 75 15 6 11 74 169 75 N N N N N N NCF4 high in P 12.8 0.000885782 3.1 76 3 9 15 80 199 201 P N N N N N SNORD22 high in P 15.5 0.000892601 3.0 77 22 5 21 156 311 230 N N N N N N NRBP1 high in P 7.1 0.00089942 3.0 78 384 413 351 3673 2470 2225 N N N N N N ATP6V0B high in P 7.3 0.000906239 3.0 79 386 487 514 4121 2580 3346 N N N N N N ZNF570 high in P 15.4 0.000926696 3.0 80 2 2 4 39 27 59 N N N N N N PIK3CG high in P 14.2 0.000933515 3.0 81 6 6 6 22 22 22 N N N N N N HLA-DOB high in P 10.9 0.000947153 3.0 82 6 6 6 22 34 24 N N N N N N NPB high in P 12 6 0.000953972 3.0 83 1 2 1 14 21 24 N N N N N N B3GNT3 high in P 7.3 0.000974429 3.0 84 23 18 29 137 160 175 N N N N N N ZIK1 high in P 26.2 0.000981248 3.0 85 2 2 2 30 33 10 N N N N N N C8orf86 high in P 16.9 0.000988067 3.0 86 39 32 91 674 949 498 NA NA N N N N NOC4L high in P 11.8 0.001001705 3.0 87 93 64 129 1166 1499 720 N N N N N N SHARPIN high in P 13.2 0.001022162 3.0 88 116 41 72 1090 898 532 N N N N N N TCP11L1 high in P 7.7 0.001028981 3.0 89 57 49 44 466 395 280 N N N N N N METTL2A high in P 8.1 0.001042618 3.0 90 32 37 22 155 224 245 N N N N N N FAM166B high in P 6.9 0.001056256 3.0 91 4 4 4 10 9 12 N N N N N N TMEM213 high in P 11.1 0.001063075 3.0 92 44 25 20 208 239 340 P P N N N N ZSCAN16 high in P 16.5 0.001076713 3.0 93 2 2 2 56 28 15 N N N N N N ZNF844 high in P 16.7 0.001090351 3.0 94 3 3 4 43 19 51 N N N N N N PHB high in P 9.4 0.00109717 3.0 95 24 18 13 89 203 99 N N N N N N CTPS high in P 10.4 0.001103989 3.0 96 47 78 31 640 710 478 N N N N N N PLEKHM1P high in P 87.8 0.001110808 3.0 97 2 3 25 330 360 349 NA NA N N N N NRN1L high in P 26.1 0.001131265 2.9 98 11 5 8 82 41 64 N N N N N N SPSB2 high in P 34.1 0.001144903 2.9 99 1 1 4 130 40 51 N N N N N N SNX5 high in P 8.0 0.001151722 2.9 100 191 97 176 1110 1440 1306 N N N N N N C9orf142 high in P 11.9 0.001158541 2.9 101 31 16 37 230 270 183 N N N N N N PHKG1 high in P 12.5 0.00116536 2.9 102 6 6 6 17 38 40 N N N N N N INHA high in P 10.8 0.001172179 2.9 103 3 3 3 42 12 14 N N N N N N FAM153B high in P 8.5 0.001178998 2.9 104 15 22 18 126 157 136 N N N N N N TMCO7 high in P 8.1 0.001192636 2.9 105 13 17 22 115 114 100 N N N N N N SMARCA4 high in P 16.8 0.001199454 2.9 106 99 155 365 2609 3972 2048 N N N N N N LOC100288730 high in P 9.0 0.001206273 2.9 107 9 4 8 75 56 83 NA NA N N N N POLG high in P 7.5 0.00122673 2.9 108 278 275 404 1883 1908 2851 N N N N N N C1orf51 high in P 19.7 0.001233549 2.9 109 20 35 67 406 646 653 N N N N N N SIN3A high in P 11.5 0.001240368 2.9 110 354 213 239 2699 2038 4280 N N N N N N SECISBP2 high in P 13.2 0.001247187 2.9 111 128 36 87 1504 1084 816 N N N N N N AMZ1 high in P 6.0 0.001267644 2.9 112 20 19 16 90 74 68 N N N N N N RBM19 high in P 9.5 0.001274463 2.9 113 64 48 84 619 781 478 N N N N N N DDX51 high in P 8.1 0.001296966 2.9 114 50 31 50 417 482 395 N N N N N N USP45 high in P 10.2 0.001303785 2.9 115 44 27 30 193 187 335 N N N N N P ZBTB7B high in P 11.2 0.001310603 2.9 116 106 46 70 736 868 554 N N N N N N SCNM1 high in P 13.3 0.001317422 2.9 117 2 13 7 174 103 91 N N N N N N ACOX3 high in P 14.3 0.001324241 2.9 118 9 20 25 160 188 230 N N N N N N ZNF554 high in P 7.4 0.00133106 2.9 119 26 20 35 217 192 212 N N N N N N SPC25 high in P 10.8 0.001337879 2.9 120 2 2 2 13 9 22 N N N N N N KIAA0562 high in P 8.9 0.001344698 2.9 121 91 52 68 558 584 444 N N N N N N TDGF1 high in P 12.3 0.001351517 2.9 122 4 4 4 15 32 12 N N N N N N CSNK2A1P high in P 9.8 0.001358336 2.9 123 177 58 144 1383 1587 1165 N N N N N N SPEG high in P 22.9 0.001371974 2.9 124 23 17 17 78 294 116 N N N P N N DEXI high in P 12.0 0.001378793 2.9 125 542 163 440 5214 4984 3872 N N N N N N CCBP2 high in P 9.1 0.00139925 2.9 126 26 33 63 272 350 298 N N N N N N ZNF384 high in P 12.2 0.001412888 2.8 127 219 81 108 1288 1373 1238 P N N N N N CYB5R2 high in P 11.3 0.001419707 2.8 128 40 36 83 664 783 342 N N N N N N LOC100128640 high in P 6.3 0.001426526 2.8 129 8 11 16 62 49 71 NA NA N N N N SLC23A3 high in P 28.8 0.001440164 2.8 130 6 6 6 29 40 211 N N N N N N CTU2 high in P 8.4 0.001446983 2.8 131 53 40 65 368 492 320 NA NA N N N N FAM32A high in P 4.9 0.001460621 2.8 132 208 239 227 1273 1068 1077 N N N N N N MRPL34 high in P 14.5 0.001474258 2.8 133 142 38 120 2032 1512 957 N N N N N N NOL6 high in P 24.8 0.001487896 2.8 134 29 20 45 305 955 521 N N N N N N SMCR8 high in P 8.8 0.001494715 2.8 135 105 69 103 847 551 840 N N N N N N RAB34 high in P 13.9 0.001501534 2.8 136 825 248 469 10393 6267 4575 N N N N N N G6PD high in P 17.2 0.001508353 2.8 137 227 174 569 7318 4141 2816 N N N N N N ACSL4 high in P 5.5 0.001515172 2.8 138 76 79 96 523 451 411 P P N N N N ANKRD34C high in P 25.1 0.001521991 2.8 139 2 2 3 33 60 32 NA NA N N N N TCHP high in P 11.1 0.001535629 2.8 140 30 12 20 203 233 222 N N N N N N UPK3B high in P 43.2 0.001542448 2.8 141 12 6 33 250 204 309 N N N N N N ST7L high in P 9.8 0.001549267 2.8 142 12 14 20 103 106 68 N N N N N N FADS6 high in P 7.9 0.001556086 2.8 143 5 5 5 20 23 22 P P N N N N ATP2A3 high in P 7.7 0.001562905 2.8 144 49 30 29 333 203 292 N N N N N N IL2RA high in P 8.0 0.001576543 2.8 145 112 58 99 670 641 903 N N N N N N LOC401127 high in P 10.9 0.001583362 2.8 146 15 7 12 72 76 152 NA NA N N N N FGFR2 high in P 7.9 0.001590181 2.8 147 67 64 82 348 498 684 N P N N N N KAT2A high in P 10.8 0.001610638 2.8 148 111 103 203 1060 964 2006 N N N N P N ATP1B4 high in P 6.3 0.001620866 2.8 149 2 2 2 9 7 7 P P N N N N XKR6 high in P 6.3 0.001620866 2.8 150 6 6 6 13 11 11 P P N N N N NUDT12 high in P 17.0 0.001631094 2.8 151 3 3 4 24 46 21 N N N N N N PAPL high in P 7.7 0.001637913 2.8 152 176 112 246 1339 1246 1774 NA NA N N N N PRKDC high in P 11.3 0.001644732 2.8 153 151 104 242 2180 1746 1086 N N N N N N LGSN high in P 12.3 0.001665189 2.8 154 7 7 8 19 34 25 N N N N N N RECQL4 high in P 14.2 0.001678827 2.8 155 14 15 25 93 160 282 N N N N N N FAM73B high in P 5.4 0.001685646 2.8 156 56 48 72 319 295 295 N N N N N N DECR2 high in P 19.1 0.001699284 2.8 157 15 30 74 334 543 519 N N N N P N PRDM11 high in P 14.7 0.001706103 2.8 158 3 3 4 9 19 28 N N N N N N NHLRC1 high in P 9.6 0.001733379 2.8 159 3 3 4 28 32 33 N N N N N N PGS1 high in P 17.4 0.001745653 2.8 160 83 16 44 1055 708 465 N N N N N N CYP2D6 high in P 10.3 0.001757927 2.8 161 2 2 2 15 13 7 N N N N N N KLC2 high in P 9.8 0.001778384 2.7 162 101 46 143 1023 1093 874 N N N N N N DUSP9 high in P 8.9 0.001792022 2.7 163 10 4 4 12 17 15 P N N N N N ZFP41 high in P 9.2 0.001798841 2.7 164 21 7 13 126 107 88 N N N N N N MGC16384 high in P 22.3 0.001812479 2.7 165 5 8 5 33 37 43 NA NA N N N N FBXO27 high in P 10.7 0.001819298 2.7 166 61 21 38 276 357 377 N N N N N N PRDX6 high in P 7.0 0.001839755 2.7 167 1633 1342 1357 14135 7418 9299 N N N N N N CHST9 high in P 7.9 0.001846573 2.7 168 12 13 13 33 38 35 P P N N N N DNAH12 high in P 6.9 0.001853392 2.7 169 13 14 15 64 78 68 NA NA N N N N FAM127A high in P 6.1 0.00186703 2.7 170 13 8 10 45 38 37 N N N N N N ERP27 high in P 8.8 0.001880668 2.7 171 2 2 3 27 16 18 N N N N N N TTC32 high in P 6.5 0.001887487 2.7 172 30 13 16 139 88 98 N N N N N N KDM5C high in P 10.9 0.001894306 2.7 173 137 58 81 815 854 807 NA NA N N N N MAK high in P 14.5 0.00190658 2.7 174 11 11 12 61 54 48 N N N N N N DCLRE1C high in P 11.5 0.001913399 2.7 175 42 22 23 275 192 278 N N N N N N TBC1D26 high in P 12.3 0.001920218 2.7 176 2 2 3 14 41 39 N N N N N N SIRPB2 high in P 72.0 0.001942721 2.7 177 3 5 26 302 154 308 N P N N N N C14orf73 high in P 7.8 0.00194954 2.7 178 2 2 3 20 29 38 N N N N N N VPS16 high in P 5.6 0.001963178 2.7 179 38 45 40 314 197 174 N N N N N N RDH16 high in P 12.2 0.001969997 2.7 180 1 1 1 25 12 6 N N N N N N TMEM222 high in P 6.8 0.001976816 2.7 181 272 171 176 1912 1709 1124 N N N N N N TSPYL2 high in P 11.4 0.001983635 2.7 182 1299 724 1755 16874 7957 24816 N N N N N N RGS12 high in P 12.9 0.001990453 2.7 183 69 34 94 543 1017 1179 N N N N N N GPR83 high in P 9.0 0.001997272 2.7 184 6 7 10 58 53 94 P P N N N N SPHK2 high in P 7.5 0.002004091 2.7 185 61 31 63 469 336 332 N N N N N N TMEM169 high in P 11.5 0.002024548 2.7 186 5 5 5 40 16 30 N N N N N N TMEM212 high in P 7.0 0.002031367 2.7 187 67 52 66 345 471 742 NA NA N N N N YIF1B high in P 6.1 0.002045005 2.7 188 13 17 17 61 76 44 N N N N N N NHLH1 high in P 8.6 0.002058643 2.7 189 4 5 6 25 51 34 N N N N N N TNFRSF4 high in P 16.1 0.002065462 2.7 190 94 19 74 924 557 1415 N N N N N N LRRC27 high in P 8.1 0.0020791 2.7 191 90 51 102 525 721 792 N N N N N N CACNB1 high in P 15.4 0.002099557 2.7 192 46 35 121 539 769 1139 N N N N N N MRTO4 high in P 10.2 0.00211865 2.7 193 88 96 206 1211 1926 938 N N N N N N YJEFN3 high in P 7.2 0.002132288 2.7 194 11 13 13 37 31 48 N N N N N N HNRNPU high in P 6.6 0.002145926 2.7 195 667 766 1090 4497 6277 7157 N N N N N N KRT27 high in P 5.4 0.002159564 2.7 196 1 1 1 7 6 6 P P N N N N PLK1S1 high in P 12.3 0.002173202 2.7 197 6 9 7 27 20 39 NA NA N N N N ANKRD45 high in P 8.9 0.002186839 2.7 198 13 6 8 54 44 51 N P N N N N CYP2R1 high in P 7.0 0.002193658 2.7 199 20 18 19 74 151 86 N N N N N N C18orf25 high in P 6.5 0.002200477 2.7 200 79 61 59 376 450 587 N N N N N N C5orf44 high in P 9.3 0.002214115 2.7 201 16 15 26 113 82 161 N N N N N N LOC729799 high in P 9.5 0.002220934 2.7 202 4 4 4 32 11 15 NA NA N N N N RPAP2 high in P 10.5 0.002227753 2.7 203 5 8 6 82 94 31 N N N N N N ANKRD11 high in P 7.4 0.002234572 2.7 204 212 224 410 1624 2078 1867 N N N N N N NONO high in P 6.3 0.002241391 2.6 205 332 393 437 2236 3456 2119 N N N N N N VN1R2 high in P 6.9 0.00224821 2.6 206 3 4 5 25 29 22 N P N N N N INVS high in P 9.3 0.002267985 2.6 207 5 5 5 15 14 22 N N N N N N ZWILCH high in P 14.6 0.002274804 2.6 208 13 6 7 78 27 42 N N N N N N FLJ25006 high in P 7.6 0.002281623 2.6 209 3 6 8 50 31 60 N N N N N N EVPL high in P 28.2 0.002317763 2.6 210 8 9 12 44 220 58 N N N N N N MTMR15 high in P 12.3 0.00233822 2.6 211 11 11 13 51 87 39 N N N N N N SLC1A5 high in P 21.8 0.002345039 2.6 212 1032 599 3953 24288 32600 22375 N N N N N N SLC37A1 high in P 8.8 0.002365496 2.6 213 40 17 59 315 426 331 N N N N N N LAT high in P 19.0 0.002379134 2.6 214 35 10 47 346 302 865 N N N N N N DRG1 high in P 37.4 0.002385953 2.6 215 2 6 36 331 275 167 N N N N N N YPEL1 high in P 6.3 0.002422093 2.6 216 16 28 28 118 195 151 N N N N P N TNFAIP8L1 high in P 5.4 0.002441186 2.6 217 195 130 198 930 1026 1042 N N N N N N IDO1 high in P 15.0 0.002495056 2.6 218 3 4 4 20 36 105 NA NA N N N N IKBKB high in P 4.9 0.002508694 2.6 219 47 63 78 325 344 419 N N N N N N KIAA0406 high in P 7.5 0.002529151 2.6 220 18 27 10 126 164 109 N N N N N N GATSL3 high in P 7.0 0.002544835 2.6 221 32 26 38 131 163 235 NA NA N N N N C7orf43 high in P 6.8 0.002585748 2.6 222 47 111 63 370 432 464 N N N N N N TRIP4 high in P 8.8 0.002606205 2.6 223 49 19 23 348 231 133 N N N N N N SNORD36C high in P 15.3 0.002619843 2.6 224 134 94 397 1362 3410 3114 N N N N N N HCCS high in P 5.5 0.002626662 2.6 225 70 60 83 492 373 308 N N N N N N ANAPC2 high in P 12.6 0.002633481 2.6 226 51 24 18 326 175 329 N N N N N N SQLE high in P 5.8 0.002645755 2.6 227 13 13 16 87 55 65 N N N N N N NHEJ1 high in P 5.8 0.002659393 2.6 228 65 44 87 371 390 365 N N N N N N CYP2B7P1 high in P 10.1 0.002666212 2.6 229 4 4 4 31 13 15 N P N N N N ZBTB5 high in P 8.0 0.002673031 2.6 230 36 24 40 207 156 266 N N N N N N LSM10 high in P 5.1 0.002685305 2.6 231 39 24 36 202 166 139 N N N N N N TSPAN31 high in P 5.2 0.002692124 2.6 232 51 47 48 240 166 265 N N N N N N CYP27C1 high in P 6.8 0.002698943 2.6 233 38 22 35 219 193 214 N N N N N N HTR7P high in P 8.6 0.002712581 2.6 234 NA NA NA NA NA NA N N N N N N CEP192 high in P 8.6 0.002726219 2.6 235 21 10 15 42 46 53 N N N N N N HAX1 high in P 7.7 0.002733038 2.6 236 295 143 139 1295 1359 1078 N N N N N N GZF1 high in P 9.1 0.002739857 2.6 237 40 19 55 300 272 368 N N N N N N RABL3 high in P 11.9 0.002753495 2.6 238 58 23 74 815 601 293 N N N N N N ACHE high in P 6.3 0.002760314 2.6 239 13 10 8 48 58 49 P N N N N N FAM115A high in P 7.9 0.002767133 2.6 240 148 92 162 703 1203 1616 N N N N P N NUDT16 high in P 6.2 0.002773952 2.6 241 23 23 17 164 74 83 N N N N N N C21orf99 high in P 7.9 0.002787589 2.6 242 2 2 2 15 18 10 NA NA N N N N LOC100216545 high in P 10.2 0.002810092 2.6 243 20 6 15 132 87 179 NA NA N N N N TCEA2 high in P 7.7 0.002825776 2.5 244 106 46 88 624 582 966 N N N N N N SFRS8 high in P 7.7 0.002832595 2.5 245 127 232 126 1023 1013 1065 N N N N N N CXorf15 high in P 13.6 0.002839414 2.5 246 NA NA NA NA NA NA N N N N N N RFPL3S high in P 10.1 0.002846233 2.5 247 3 8 4 38 40 51 N N N N N N ZNF274 high in P 6.3 0.002853051 2.5 248 75 45 73 531 418 268 N N N N N N NXNL2 high in P 7.8 0.002866689 2.5 249 11 9 17 92 65 72 N N N N P N MFSD7 high in P 14.9 0.002873508 2.5 250 35 16 66 361 345 279 N N N N N N UTP6 high in P 5.9 0.002880327 2.5 251 59 81 42 290 409 320 N N N N N N MXD3 high in P 9.4 0.002887146 2.5 252 28 11 23 166 238 141 N N N N N N BNIP2 high in P 4.3 0.00290283 2.5 253 71 62 67 296 295 234 N N N N N N KPTN high in P 10.1 0.002923287 2.5 254 73 25 64 293 507 607 N N N N N N DBF4B high in P 5.8 0.002930106 2.5 255 272 190 229 1009 1214 1531 N N N N N N RBBP9 high in P 11.9 0.002936925 2.5 256 23 18 37 128 194 113 N P N N N N DOCK9 high in P 14.5 0.002943744 2.5 257 56 28 24 260 214 307 N N N N N N NEDD4 high in P 5.4 0.002971019 2.5 258 12 13 15 52 53 42 N N N N N N ASF1A high in P 5.1 0.002977838 2.5 259 68 57 88 353 342 400 N N N N N N KCNRG high in P 6.8 0.002984657 2.5 260 2 2 3 18 12 18 N N N N N N REEP4 high in P 7.0 0.002998295 2.5 261 46 16 40 278 285 183 N N N N N N WFDC8 high in P 10.4 0.003005114 2.5 262 9 3 6 39 23 30 N N N N N N SLFN13 high in P 6.6 0.00303239 2.5 263 18 22 32 143 140 190 N N N N N N SPPL2B high in P 10.1 0.003039209 2.5 264 175 41 146 1181 1465 1668 N N N N N N FGF5 high in P 6.8 0.003052847 2.5 265 33 21 37 165 126 215 P P N N P N EXTL3 high in P 17.4 0.003059666 2.5 266 107 33 78 2127 1033 482 N N N N N N SNORA57 high in P 16.9 0.003066485 2.5 267 7 5 1 24 33 104 N N N N N N JRK high in P 5.4 0.003073304 2.5 268 34 36 32 150 135 166 N N N N N N DDHD2 high in P 7.0 0.003080123 2.5 269 25 25 20 136 123 99 N N N N N N CCNJ high in P 5.2 0.003093761 2.5 270 15 21 23 92 64 61 N N N N N N KIAA1161 high in P 9.6 0.00310058 2.5 271 11 17 37 128 159 189 N N N N N N DHX8 high in P 9.2 0.003107399 2.5 272 92 23 77 586 806 640 N N N N N N NPW high in P 18.2 0.003114218 2.5 273 1 3 8 46 134 67 N N N N N N USP54 high in P 5.6 0.003127855 2.5 274 45 35 54 208 217 153 N N N N N N C5orf56 high in P 8.9 0.003141493 2.5 275 8 8 8 29 27 39 NA NA N N N N TYMP high in P 8.0 0.003148312 2.5 276 701 552 696 17914 4646 4081 N N N N N N LRCH4 high in P 10.4 0.00316195 2.5 277 141 50 208 1038 1520 1674 N N N N N N BRF1 high in P 8.8 0.003175588 2.5 278 98 28 78 678 603 748 N N N N N N SETD8 high in P 8.6 0.003182407 2.5 279 277 181 476 1698 2329 2560 N N N N N N WDR45 high in P 6.4 0.003189226 2.5 280 279 149 248 1854 1275 1196 N N N N N N NCAPD3 high in P 8.9 0.003209001 2.5 281 10 25 12 89 114 70 N N N N N N MOCS3 high in P 4.9 0.00321582 2.5 282 20 15 17 57 45 70 N N N N N N RPL9 high in P 5.2 0.003222639 2.5 283 8530 8736 11346 47216 64079 39995 N N N N N N CDH24 high in P 10.4 0.003249915 2.5 284 17 7 21 79 148 116 N N N N P N C12orf10 high in P 6.3 0.003256734 2.5 285 301 196 185 1843 1213 1120 N N N N N N RNF208 high in P 6.1 0.003263553 2.5 286 3 9 6 53 37 27 N N N N N N DNM1L high in P 4.6 0.003270372 2.5 287 73 122 131 644 606 547 N N N N N N LAMP3 high in P 6.5 0.003277191 2.5 288 9 14 11 44 67 75 P N N N N N METT11D1 high in P 7.9 0.003290147 2.5 289 208 102 163 1185 1293 705 N N N N N N DGKZ high in P 6.7 0.003296966 2.5 290 56 39 53 222 354 415 N N N N N N PHF5A high in P 4.5 0.003303785 2.5 291 97 96 126 583 521 385 N N N N N N PPIF high in P 5.4 0.003317422 2.5 292 285 360 532 1764 2404 1966 N N N N N N POM121 high in P 5.6 0.00333106 2.5 293 38 24 27 118 148 144 N N P N N N SLC14A1 high in P 10.3 0.003346744 2.5 294 43 22 69 249 443 447 N P N N N N IL1RL1 high in P 10.2 0.003353563 2.5 295 91 445 245 2681 3356 2140 N P N N N N ZFAND2B high in P 8.8 0.003360382 2.5 296 20 26 51 221 161 211 N N N N N N DDX39 high in P 6.6 0.003367201 2.5 297 479 279 704 3368 2639 4105 N N N N N N TIPIN high in P 5.0 0.00337402 2.5 298 14 5 8 38 35 30 N N N N N N KREMEN1 high in P 4.9 0.003387658 2.5 299 33 36 51 203 204 227 N N N N N N MPHOSPH6 high in P 10.2 0.003394477 2.5 300 23 52 49 325 543 246 P N N N N N MZF1 high in P 6.5 0.003401296 2.5 301 46 46 78 267 308 274 N N N N N N TRIM14 high in P 6.8 0.003414934 2.5 302 33 24 20 81 123 150 N N N N N N MTHFR high in P 9.2 0.003428571 2.5 303 190 75 141 1324 912 2174 N N N N N N RNASEH2C high in P 10.9 0.00343539 2.5 304 10 10 13 104 56 31 N N N N N P DAXX high in P 6.5 0.003442209 2.5 305 544 237 515 2686 3549 2728 N N N N N N HHIPL1 high in P 12.4 0.003449028 2.5 306 23 7 10 168 98 98 N N N N N N SNX22 high in P 6.2 0.003455847 2.5 307 25 37 47 172 212 326 N N N N N N SLC25A1 high in P 11.6 0.003462666 2.5 308 211 69 97 1390 1139 726 N N N N N N HOXB6 high in P 6.5 0.003483123 2.5 309 17 4 9 74 40 49 P P N P N N KRBA2 high in P 6.1 0.003524719 2.5 310 161 65 119 697 709 718 N N N N N N PARP8 high in P 4.6 0.003531538 2.5 311 18 24 18 70 65 86 N N N N N N LMAN2L high in P 9.5 0.003551995 2.4 312 124 27 63 491 585 561 N N N N N N PNLDC1 high in P 5.2 0.003565632 2.4 313 19 7 10 49 31 53 N N N N N N ITGA10 high in P 5.8 0.003572451 2.4 314 13 44 43 141 163 209 N N N N N N SCRIB high in P 12.1 0.00357927 2.4 315 104 30 133 1078 1323 998 N N N N N N CBLL1 high in P 5.1 0.003598363 2.4 316 99 68 78 393 407 344 N N N N N N IRF3 high in P 9.2 0.003612001 2.4 317 51 18 26 224 209 238 N N N N N N CHMP6 high in P 10.4 0.003648142 2.4 318 48 14 35 384 316 139 N N N N N N HOXC11 high in P 19.4 0.003668599 2.4 319 2 2 2 23 8 55 P P N N N N C2orf15 high in P 5.5 0.003675418 2.4 320 170 100 143 629 767 880 N N N N N N PRC1 high in P 11.3 0.003682237 2.4 321 17 6 8 59 30 54 N N N N N N TNFRSF1B high in P 8.8 0.003694511 2.4 322 696 154 745 4534 5317 6637 N N N N N N FLVCR1 high in P 9.4 0.00370133 2.4 323 13 25 14 59 124 122 N N N N N N DNAJC8 high in P 6.7 0.003708149 2.4 324 224 195 415 1951 1473 1411 N N N N N N RASSF4 high in P 10.4 0.003714968 2.4 325 76 14 64 534 393 742 N N N N P N STEAP3 high in P 9.9 0.003721787 2.4 326 10 12 14 65 250 51 N N N N N N RPS19BP1 high in P 9.4 0.003735424 2.4 327 79 25 24 431 467 185 N N N N P N EFHC1 high in P 4.4 0.003749062 2.4 328 45 50 46 192 261 261 N N N N N N RASSF7 high in P 11.4 0.003769519 2.4 329 23 23 58 151 599 503 N N N N N P DDA1 high in P 5.7 0.003783157 2.4 330 586 379 610 3335 4052 2377 N N N N N N GFER high in P 8.8 0.003789976 2.4 331 85 38 47 480 293 370 N N N N N N SFRS14 high in P 6.5 0.003796795 2.4 332 56 35 47 229 377 255 N N N N N N MNAT1 high in P 14.1 0.003824071 2.4 333 47 8 21 470 325 139 N N N N N N MGC12982 high in P 17.8 0.00383089 2.4 334 3 3 5 82 15 86 NA NA N N N N C19orf76 high in P 13.5 0.003837709 2.4 335 47 28 63 192 584 801 NA NA N N N N YTHDF2 high in P 5.0 0.003858166 2.4 336 869 448 932 3988 4335 4175 N N N N N N FBXW5 high in P 11.7 0.003879986 2.4 337 497 141 417 6147 3497 2061 N N N N N N ZNF169 high in P 7.2 0.003900443 2.4 338 4 4 4 23 15 12 N N N N N N EIF4ENIF1 high in P 5.5 0.0039209 2.4 339 69 41 57 229 328 276 N N N N N N APPBP2 high in P 4.6 0.003927719 2.4 340 46 54 61 229 215 331 N N N N N N LOC100170939 high in P 8.6 0.003942039 2.4 341 8 2 2 22 15 22 N N N N N N ADORA3 high in P 8.8 0.003955677 2.4 342 3 3 4 20 10 26 N N N N N N ITGB7 high in P 18.5 0.004003409 2.4 343 28 10 12 55 176 492 N N N N N N MRPL32 high in P 5.8 0.004010228 2.4 344 599 396 366 1948 2932 2223 N N N N N N SMUG1 high in P 4.6 0.004017047 2.4 345 20 19 21 76 82 59 N N N N N N MYO19 high in P 4.6 0.004023866 2.4 346 37 51 67 252 322 178 N N N N N N CCDC127 high in P 12.5 0.004030685 2.4 347 15 33 87 416 518 381 N N N N N N ADC high in P 11.4 0.004037504 2.4 348 37 31 47 143 396 492 N N N N N N RPL23AP82 high in P 7.9 0.004057961 2.4 349 2 2 2 10 10 13 NA NA N N N N SRRD high in P 6.0 0.00406478 2.4 350 52 26 26 159 217 111 N N N N N N INSL3 high in P 11.5 0.004078418 2.4 351 2 2 3 14 16 41 P N N N N N GCHFR high in P 12.5 0.004092056 2.4 352 2 11 14 135 87 133 N N N N N N RNF26 high in P 5.6 0.004105694 2.4 353 115 50 103 651 497 435 N N N N N N KIAA1919 high in P 9.3 0.004112513 2.4 354 28 8 17 92 118 107 N N N N N N RRN3P3 high in P 5.1 0.004119332 2.4 355 442 266 585 2623 2245 2282 NA NA N N N N MRPL14 high in P 6.7 0.004126151 2.4 356 406 267 144 1647 2323 1514 N N N N N N UPF3B high in P 4.6 0.004158882 2.4 357 62 30 50 219 250 218 N N N N N N AFG3L1 high in P 6.0 0.004177975 2.4 358 25 18 41 203 129 129 N N N N P N PSMG4 high in P 5.1 0.004191613 2.4 359 53 34 32 159 253 258 N N N N N N NDOR1 high in P 4.6 0.004198432 2.4 360 56 33 59 272 244 246 N N N N N N PLXNB1 high in P 6.7 0.00421207 2.4 361 116 126 180 892 1702 545 N N N N N N C6orf145 high in P 7.0 0.004225707 2.4 362 1195 970 2144 9400 6242 14625 N N N N N N FBXL8 high in P 13.1 0.004239345 2.4 363 23 2 5 130 76 77 N N N N N N SLC39A13 high in P 9.0 0.004263212 2.4 364 429 142 217 1818 2212 1575 N N N N N N DNAJC9 high in P 4.8 0.004270031 2.4 365 15 11 9 45 50 32 N N N N N N NSMCE1 high in P 16.0 0.00427685 2.4 366 29 8 16 200 200 83 N N N N N N NCOR2 high in P 10.6 0.004297307 2.4 367 218 128 102 1276 875 1658 N N N N N N FLJ14107 high in P 8.8 0.004310944 2.4 368 4 4 4 21 29 10 NA NA N N N N MECR high in P 4.4 0.004330038 2.4 369 27 32 45 160 147 107 N N N N N N CCDC61 high in P 7.7 0.004336856 2.4 370 3 4 8 71 40 24 N N N N N N ZSCAN5A high in P 12.3 0.004350494 2.4 371 4 4 5 34 17 17 N N N N N N C19orf77 high in P 8.2 0.00437777 2.4 372 3 3 4 15 26 11 NA NA N N N N GIGYF1 high in P 5.1 0.004384589 2.4 373 173 146 267 1066 956 989 N N N N N N NOL12 high in P 5.3 0.004391408 2.4 374 44 23 27 167 134 126 N N N P N N NCAPH high in P 6.3 0.004398227 2.4 375 13 6 6 16 14 12 N N N N P N TMEM229B high in P 10.1 0.004405046 2.4 376 6 6 6 34 22 12 NA NA N N N N SURF2 high in P 8.5 0.004434368 2.4 377 2 2 3 23 19 8 N N N N N N C9orf80 high in P 5.8 0.004454824 2.4 378 57 18 43 253 246 232 N N N N N N CYP8B1 high in P 8.4 0.004475281 2.3 379 3 6 6 35 30 51 N N N N N N COPS7B high in P 7.2 0.004495738 2.3 380 10 8 10 64 24 66 N N N N N N WDR43 high in P 5.9 0.004502557 2.3 381 228 242 207 890 1956 1366 N N N N N N POM121L8P high in P 5.2 0.004509376 2.3 382 24 26 20 82 82 112 NA NA N N N N FUT5 high in P 7.1 0.004536652 2.3 383 16 6 7 33 40 73 N N N N N N COLQ high in P 5.8 0.00455029 2.3 384 8 18 20 55 55 92 N N N N N N LRRC37A3 high in P 14.8 0.004557109 2.3 385 28 2 4 85 93 164 N N N N N N ABCB4 high in P 17.7 0.004563928 2.3 386 2 4 9 25 83 61 N N N N N N ABCC13 high in P 4.0 0.004584385 2.3 387 24 14 14 63 60 67 P P N N N N UCN high in P 14.5 0.004591204 2.3 388 2 8 3 55 39 23 N P N N N N LAMC3 high in P 8.6 0.004598023 2.3 389 187 101 173 901 1369 3215 N N N N N N NOL7 high in P 25.9 0.004604841 2.3 390 9 9 9 96 74 15 N N N N N N SLC13A3 high in P 5.8 0.004625298 2.3 391 9 14 10 41 52 42 N N N N N N THPO high in P 7.1 0.004632117 2.3 392 2 3 6 35 20 32 N N N N N N ARL16 high in P 7.4 0.004652574 2.3 393 191 111 232 920 1629 828 N N N N N N KCNH3 high in P 7.7 0.004673031 2.3 394 21 13 22 68 122 53 N N N N N N SETDB1 high in P 7.4 0.00467985 2.3 395 17 26 47 171 164 110 N N N N N N GPR137 high in P 6.8 0.004686669 2.3 396 87 45 157 768 567 539 N N N N N P PLCH2 high in P 12.3 0.004712581 2.3 397 17 17 17 23 52 30 P N N N N N TRABD high in P 3.6 0.004726219 2.3 398 167 225 198 687 760 772 N N N N N N KIAA0664 high in P 8.7 0.004733038 2.3 399 105 187 51 811 1477 1065 N N N N N N SFI1 high in P 6.9 0.004746676 2.3 400 17 14 26 81 120 66 N N N N N N MTFMT high in P 4.1 0.004753495 2.3 401 19 13 11 60 51 37 N N N N N N STEAP1 high in P 7.0 0.004767133 2.3 402 68 32 49 898 328 209 N N N N N N DDR2 high in P 11.8 0.004780771 2.3 403 113 28 35 889 467 312 N N N N N N TMCO2 high in P 7.1 0.004787589 2.3 404 1 1 1 7 6 24 N N N N N N C15orf57 high in P 4.6 0.004794408 2.3 405 42 27 28 144 190 120 N N N N N N MYNN high in P 4.1 0.00482032 2.3 406 47 39 48 211 139 175 N N N N N N IL17RA high in P 4.1 0.004827139 2.3 407 47 44 57 207 207 164 N N N N N N HN1L high in P 5.3 0.004833958 2.3 408 347 225 352 1285 2190 1566 N N N N N N ZNF18 high in P 15.5 0.004847596 2.3 409 6 7 9 122 28 36 N N N N N N CAPG high in P 5.0 0.004854415 2.3 410 133 105 182 599 616 857 N N N N N N KDM2A high in P 4.8 0.004861234 2.3 411 591 391 578 3097 2242 2961 NA NA N N N N LOC442421 high in P 9.2 0.004874872 2.3 412 9 9 9 59 27 37 P P N N N N PI4K2A high in P 6.6 0.00488851 2.3 413 754 746 1594 4234 6022 9886 N N N N N N RAB4B high in P 6.0 0.004895329 2.3 414 14 12 11 43 41 24 N N N N N N CHMP1A high in P 5.6 0.004902148 2.3 415 502 276 449 2803 2664 1708 N N N N N N ALDOC high in P 3.9 0.004922605 2.3 416 31 40 35 107 122 136 N N N N N N ARPM1 high in P 5.7 0.004929424 2.3 417 6 6 6 13 19 13 N N N N N N LETM2 high in P 7.2 0.004943062 2.3 418 3 4 9 22 36 38 N N N N N N RNF123 high in P 5.0 0.004963519 2.3 419 83 54 59 447 322 237 N N N N N N PYCRL high in P 6.0 0.004970338 2.3 420 39 21 31 102 166 148 N N N N N N ZNF425 high in P 8.1 0.004977156 2.3 421 98 26 36 320 310 405 N N N N N N WDR81 high in P 11.7 0.004997613 2.3 422 75 58 102 2165 321 964 NA NA N N N N SULT1A4 high in P 10.2 0.005004432 2.3 423 27 72 96 339 713 780 N N N N N N TEP1 high in P 5.3 0.005011251 2.3 424 60 50 75 312 360 199 N N N N N N FAM164C high in P 5.9 0.00501807 2.3 425 4 4 5 17 24 20 N N N N N N SRRT high in P 6.0 0.005024889 2.3 426 435 261 746 2548 3421 2779 NA NA N N N N ERLIN1 high in P 7.5 0.005038527 2.3 427 251 55 298 1917 1424 1856 N N N N N N WDR90 high in P 4.3 0.005045346 2.3 428 16 24 21 79 60 52 N N N N N N BTN2A2 high in P 15.5 0.005052165 2.3 429 32 6 10 143 68 161 N N N N N N NXF1 high in P 6.3 0.005065803 2.3 430 1779 992 1695 5615 10060 12393 N N N N N N TMEM63A high in P 7.2 0.005072622 2.3 431 31 18 27 203 167 156 N N N N N N SF3B2 high in P 5.3 0.005093761 2.3 432 269 245 261 1743 1448 872 P N N N N N ZNF592 high in P 4.5 0.005107399 2.3 433 90 87 128 568 417 608 N N N N N N C8orf33 high in P 3.9 0.005114218 2.3 434 129 183 205 894 745 775 N N N N N N C15orf61 high in P 6.9 0.005134674 2.3 435 99 23 60 375 417 387 NA NA N N N N CROCCL1 high in P 8.0 0.005141493 2.3 436 44 40 12 337 154 283 NA NA N N N N GTF2IRD1 high in P 6.4 0.00516195 2.3 437 63 68 123 378 503 334 N N N P N N VHL high in P 4.6 0.005175588 2.3 438 228 138 256 1150 824 923 N N N N N N FBXL14 high in P 5.5 0.005182407 2.3 439 13 7 8 22 22 55 N N N N N N AKNA high in P 9.4 0.005189226 2.3 440 376 102 721 2930 3808 6079 N N N N N N C9orf41 high in P 8.3 0.005202864 2.3 441 28 8 29 132 168 268 N N N N N N ZNF493 high in P 4.6 0.005218548 2.3 442 194 150 188 766 651 1007 N N N N N N NLE1 high in P 7.5 0.005232185 2.3 443 127 59 98 470 915 414 N N N N N N CHST6 high in P 5.6 0.005245823 2.3 444 85 71 49 339 392 463 N N N N N N RPS6KB2 high in P 5.3 0.005252642 2.3 445 7 12 14 39 71 32 N N N N N N RRP7B high in P 7.6 0.005259461 2.3 446 13 11 15 39 116 87 N N N N P N ZNF77 high in P 9.1 0.00526628 2.3 447 12 13 6 33 36 28 N N N N N N SHF high in P 5.9 0.005290147 2.3 448 98 34 72 332 363 532 N N N N N N C16orf54 high in P 4.1 0.005296966 2.3 449 12 23 17 63 58 65 N N N N N N SHKBP1 high in P 5.8 0.005311967 2.3 450 80 77 112 1082 410 386 N N N N N N CYP2B6 high in P 5.2 0.005339925 2.3 451 6 7 8 29 27 30 N P N N N N MYOM1 high in P 11.0 0.005346744 2.3 452 17 11 13 35 75 126 N N N N N N C10orf118 high in P 5.5 0.005360382 2.3 453 31 43 62 174 183 212 N N N N N N PIK3R1 high in P 6.5 0.005389703 2.3 454 341 201 160 2483 1648 991 N N P N N N FBXO40 high in P 5.7 0.005403341 2.3 455 5 5 5 15 12 18 N N N N N N POP4 high in P 8.9 0.005416979 2.3 456 11 5 8 79 45 25 N N N N N N CACNA1G high in P 26.5 0.005423798 2.3 457 219 54 169 1317 1261 9394 N N N N N N LOC440944 high in P 4.0 0.00544971 2.3 458 40 56 72 208 214 266 NA NA N N N N ZNF321 high in P 5.7 0.005475622 2.3 459 125 111 223 604 759 938 N N N N N N SGK269 high in P 13.1 0.005482441 2.3 460 140 104 254 745 2411 3389 N N N N N N KCNK6 high in P 5.6 0.00548926 2.3 461 12 15 17 50 55 86 N N N N N N XPO5 high in P 5.3 0.005496079 2.3 462 42 68 63 293 292 152 N N N N N N MON1A high in P 4.8 0.005502898 2.3 463 19 19 13 41 43 42 N N N N N N ST7OT1 high in P 5.1 0.005515172 2.3 464 38 15 16 131 93 72 N N N N N N ADCK5 high in P 11.8 0.005521991 2.3 465 32 6 16 213 121 164 N N N N N N RNMTL1 high in P 4.4 0.005535629 2.3 466 44 56 29 231 170 166 N N N N N N FOXP3 high in P 8.0 0.005542448 2.3 467 3 3 3 16 22 16 P N N N N N PCMT1 8 high in P 5.4 0.005549267 2.3 468 572 329 316 2368 1849 1651 N N N N N N FAM41C high in P 9.0 0.005556086 2.3 469 34 18 66 201 350 259 NA NA N N N N KLHDC9 high in P 8.9 0.005562905 2.3 470 1 1 2 9 27 33 N N N N N N BTG3 high in P 14.6 0.005617457 2.3 471 55 11 17 268 192 185 N N N N N N OSTF1 high in P 11.4 0.005629731 2.2 472 259 58 60 1097 646 1305 N N N N N N MGC3771 high in P 6.3 0.00563655 2.2 473 3 3 3 11 9 14 N N N N N P HIP1R high in P 10.3 0.005650188 2.2 474 125 56 180 537 2207 1277 N N N N N N NCS1 high in P 4.0 0.0056761 2.2 475 594 425 569 2061 2661 2177 NA NA N N N N APOL1 high in P 5.9 0.005689737 2.2 476 8 9 8 21 19 25 N N N N N N PARP10 high in P 8.8 0.005696556 2.2 477 128 20 93 682 597 1108 N N N N N N CXCL1 high in P 6.0 0.005703375 2.2 478 158 305 384 1067 1886 1701 N N N N N N ZNF530 high in P 3.9 0.005710194 2.2 479 6 7 9 19 22 26 N N N N N N MDH1 high in P 4.1 0.005717013 2.2 480 242 221 203 1028 863 682 N N N N N N PTPRCAP high in P 9.6 0.00573747 2.2 481 19 11 33 117 83 315 N N N N N N SCFD2 high in P 5.2 0.005757927 2.2 482 9 16 9 54 54 62 P P N N N N PAOX high in P 6.5 0.005812479 2.2 483 4 4 4 17 11 10 N N N N N N TIPRL high in P 4.9 0.005826117 2.2 484 105 109 72 609 412 385 N N N N N N STX1A high in P 6.6 0.005832936 2.2 485 20 30 58 114 270 240 N N N N N N AATK high in P 12.6 0.005846573 2.2 486 7 8 10 26 35 23 N N N N N N MBD4 high in P 3.9 0.005877259 2.2 487 308 195 258 1028 996 1023 N N N N N N USF1 high in P 6.8 0.005884078 2.2 488 4 4 7 33 25 48 P N N N N N CSTF3 high in P 5.4 0.005890897 2.2 489 19 12 9 45 62 85 N N N N N N TAF10 high in P 5.7 0.005904535 2.2 490 435 144 294 1564 1828 1506 N N N N N N SNAI3 high in P 11.9 0.005911354 2.2 491 3 3 5 26 56 510 N N N N N N TAF1C high in P 9.3 0.005918173 2.2 492 40 61 161 525 505 583 N N N N N N GFM1 high in P 5.7 0.005924991 2.2 493 55 53 41 300 340 147 N N N N N N DPF2 high in P 5.7 0.005938629 2.2 494 66 38 106 381 360 404 N N N N N N MPHOSPH10 high in P 4.2 0.005959086 2.2 495 100 120 164 614 629 399 N N N N N N FAM3A high in P 7.0 0.005965905 2.2 496 77 99 222 1227 626 599 N N N N N N PVT1 high in P 12.9 0.005972724 2.2 497 138 85 87 511 4208 1098 N N N N N N CENPA high in P 6.3 0.005993181 2.2 498 4 4 5 14 11 10 N N N N N N C9orf78 high in P 5.1 0.006 2.2 499 118 198 131 831 605 653 N N N N N N TKTL1 high in P 18.6 0.006027276 2.2 500 3 5 16 73 36 117 N N N N N N ZNF394 high in P 5.6 0.006049778 2.2 501 4 5 6 20 22 15 N N N N N N SLC35B1 high in P 7.1 0.006056597 2.2 502 220 132 275 2799 1586 766 N N N N N N SCT high in P 12.9 0.006110467 2.2 503 2 2 3 8 20 45 N N N N N N TRMT61B high in P 4.9 0.006132288 2.2 504 17 17 7 54 67 50 NA NA N N N N RPL18 high in P 4.8 0.006145926 2.2 505 3490 2432 5137 16900 16128 21500 N N N N N N STOML1 high in P 7.7 0.006159564 2.2 506 19 8 14 41 61 38 N N N N N N ISOC2 high in P 4.9 0.006166383 2.2 507 86 81 113 536 490 270 N N N N N N SLC43A2 high in P 7.7 0.006173202 2.2 508 204 103 78 873 538 725 N N N N N N LOC285456 high in P 6.0 0.006193658 2.2 509 3 5 7 20 21 31 NA NA N N N N C4orf52 high in P 6.1 0.006207296 2.2 510 5 5 7 20 16 30 NA NA N N N N UCKL1 high in P 6.1 0.006214115 2.2 511 238 83 217 1423 1035 806 N N N N N N LOC100133991 high in P 4.7 0.006227753 2.2 512 9 7 4 18 20 32 N N N N N N CCDC71 high in P 5.1 0.006241391 2.2 513 65 32 56 256 218 143 N N N N N N MED11 high in P 5.8 0.006255029 2.2 514 55 25 20 247 214 89 N N N N N N INPP5K high in P 6.3 0.006275486 2.2 515 20 39 30 167 91 269 N N N N N N ZGPAT high in P 8.3 0.006315036 2.2 516 36 11 20 149 134 150 N N N N P N C1orf84 high in P 6.0 0.006321855 2.2 517 25 5 20 118 83 124 N N N N N N CAPZB high in P 7.7 0.006328674 2.2 518 2249 597 1035 14132 7767 6290 N N N N N P ZNF845 high in P 8.4 0.006335493 2.2 519 2 2 2 33 15 10 P P N N N N HTATSF1 high in P 3.8 0.006349131 2.2 520 8 14 14 44 49 54 P P N N N N CRCP high in P 5.4 0.00635595 2.2 521 39 29 28 98 158 198 NA NA N N N N FLJ39582 high in P 6.3 0.006369587 2.2 522 36 7 28 179 123 125 NA NA N N N N RHOD high in P 6.8 0.006408456 2.2 523 55 23 39 244 694 147 N N N N N N ZNF397OS high in P 4.8 0.006427549 2.2 524 18 13 26 75 68 107 N N N N N N MTAP high in P 3.3 0.006441186 2.2 525 49 55 63 150 166 148 N P N N N N PARD6A high in P 7.0 0.006468462 2.2 526 6 6 6 19 11 23 N N N N P N SNRPA high in P 5.6 0.0064821 2.2 527 438 168 407 2663 1438 1924 N N N N N N LOC643008 high in P 7.1 0.006488919 2.2 528 15 10 13 63 49 73 N N N N N N LOC146880 high in P 7.9 0.006495738 2.2 529 4 5 18 49 82 43 NA NA N N N N FANCB high in P 44.2 0.006502557 2.2 530 28 2 2 55 53 68 N N N N N N DPP3 high in P 6.0 0.006509376 2.2 531 23 23 29 172 121 63 N N N N N N S100A13 high in P 8.9 0.006516195 2.2 532 10 10 12 18 28 28 N N N N N N C6orf59 high in P 6.8 0.006523014 2.2 533 9 3 3 9 8 16 NA NA N N N N C19orf24 high in P 5.4 0.00655029 2.2 534 21 32 15 110 156 80 N N N N N N CD79A high in P 8.6 0.006557109 2.2 535 3 3 4 11 17 35 N N N N N N DMXL1 high in P 7.8 0.006579611 2.2 536 63 34 37 311 158 173 N N N N N N GPRIN1 high in P 7.0 0.00658643 2.2 537 5 10 17 65 66 59 P N N N N N PSMB2 high in P 7.6 0.006593249 2.2 538 409 522 458 3924 3308 1423 N P N N N N KPNA5 high in P 4.6 0.006600068 2.2 539 6 11 14 29 39 59 N N N N N N OXT high in P 14.3 0.006606887 2.2 540 1 1 4 14 19 26 P N N N N N MYLPF high in P 8.2 0.006613706 2.2 541 1 5 2 24 46 16 N N N N N P GRID1 high in P 17.4 0.006623935 2.2 542 128 23 29 738 307 384 N N N N N N C6orf136 high in P 4.2 0.00665462 2.2 543 29 28 42 128 113 113 N N N N N N ZSCAN21 high in P 4.5 0.006675077 2.2 544 5 11 17 68 59 33 N N N N N N LOC283314 high in P 6.5 0.006681896 2.2 545 45 32 38 159 197 211 NA NA N N N N C8orf75 high in P 5.2 0.006688715 2.2 546 9 2 3 7 12 10 NA NA N N N N FBXL15 high in P 5.1 0.006702353 2.2 547 68 41 90 460 244 264 N N N N N N TULP2 high in P 13.2 0.006741221 2.2 548 15 4 4 34 17 79 N N N N N N C20orf4 high in P 7.8 0.006754859 2.2 549 6 60 51 432 469 298 N N N N N N SLC25A10 high in P 3.7 0.006761677 2.2 550 12 12 10 45 32 29 N N N N N N PKP4 high in P 7.0 0.006775315 2.2 551 444 219 359 1551 3685 1578 N N N N N N EEF1A2 high in P 8.5 0.006795772 2.2 552 7 13 30 193 247 52 N P N N N N FAM50B high in P 14.6 0.006802591 2.2 553 32 6 8 98 79 92 N N N N N N FGFRL1 high in P 6.1 0.00680941 2.2 554 71 129 158 476 1357 812 N N N N N N SLC25A22 high in P 4.7 0.006823048 2.2 555 18 9 16 61 76 52 N N N N N N DGKE high in P 4.5 0.006829867 2.2 556 94 93 128 402 459 672 N N N N N N IDH3G high in P 4.7 0.006836686 2.2 557 97 82 60 451 402 250 N N N N N N FANCC high in P 8.5 0.006865326 2.2 558 24 18 43 96 218 273 N N P N N N PHB2 high in P 5.4 0.006872145 2.2 559 2195 780 3065 13187 13962 9947 N N N N N N ATP5J2 high in P 4.7 0.006878964 2.2 560 35 26 22 118 173 71 N N N N P N NSFL1C high in P 5.9 0.006885782 2.2 561 297 376 642 3476 3640 1508 N N N N N N CSF3R high in P 10.1 0.006892601 2.2 562 9 9 12 28 47 214 P N N N N N TAF3 high in P 9.0 0.00689942 2.2 563 148 50 42 475 390 467 P P N N N N PLIN5 high in P 6.5 0.006918513 2.2 564 22 9 25 81 166 99 NA NA N N N N SART1 high in P 4.5 0.006925332 2.2 565 257 171 327 1136 1350 829 N P N N N N ZNF500 high in P 5.1 0.00693897 2.2 566 18 11 19 63 91 53 N N N N N N CHTF18 high in P 10.2 0.006959427 2.2 567 94 22 41 277 390 863 N N N N N N TYMS high in P 10.6 0.006973065 2.2 568 12 6 6 29 57 28 N N N N N N HSD11B1 high in P 13.7 0.006986703 2.2 569 31 56 187 766 515 715 N N N N N N GGT8P high in P 6.4 0.00700716 2.2 570 15 4 5 30 15 24 N P N N N N TBRG4 high in P 7.1 0.007027617 2.2 571 119 179 411 1675 1805 827 N N N N N N DNHD1 high in P 9.8 0.007034436 2.2 572 49 32 43 305 185 208 N N N N N N DPY19L2P2 high in P 7.5 0.007041255 2.2 573 28 12 12 49 49 40 N N N N N N FBXO10 high in P 16.5 0.007054893 2.2 574 59 13 20 204 188 272 N N N N N N HMOX2 high in P 7.0 0.007061712 2.2 575 350 106 285 1877 2048 1043 N N N N N N AES high in P 6.4 0.007068531 2.2 576 3213 806 1852 10796 11526 11735 N N N N N N GSC high in P 6.9 0.007088987 2.1 577 49 14 50 341 132 275 N N N N N N MDM4 high in P 4.1 0.007138766 2.1 578 69 85 143 697 534 468 N N N N N N GP5 high in P 6.4 0.007159223 2.1 579 6 6 6 17 11 26 N N N P N P SLAMF6 high in P 6.1 0.007166042 2.1 580 5 5 5 11 10 14 N N N N N N SBF1 high in P 6.3 0.007205592 2.1 581 26 38 109 309 423 425 N N N N N N CNGB1 high in P 5.6 0.007212411 2.1 582 17 11 12 21 24 31 N N N N N N SLED1 high in P 15.1 0.007219229 2.1 583 2 3 12 29 49 169 N N N N N N PANK4 high in P 9.6 0.007232867 2.1 584 109 86 348 880 1066 1039 N P N N N N LOC654433 high in P 16.2 0.007239686 2.1 585 11 12 14 126 271 27 N N N N N N SLC7A5P2 high in P 5.0 0.007260143 2.1 586 13 27 35 85 80 127 NA NA N N N N INPP5D high in P 7.3 0.007290147 2.1 587 16 12 17 51 61 294 N N N N N N GPC2 high in P 7.8 0.007302421 2.1 588 5 5 5 18 19 15 N N N N N N ABCD1 high in P 5.1 0.00730924 2.1 589 59 43 58 178 166 296 N N N N N N USP13 high in P 3.4 0.007342653 2.1 590 76 75 76 269 321 255 N N N N N N UNC13D high in P 5.5 0.00735629 2.1 591 18 32 56 121 143 283 N N N N N N B3GAT1 high in P 17.7 0.007412888 2.1 592 9 9 9 17 148 45 P P N N N N DUOX2 high in P 9.3 0.007419707 2.1 593 7 9 8 17 73 25 P P N N N N AVPI1 high in P 5.6 0.007426526 2.1 594 60 20 26 144 129 220 N N N N N N DNASE1 high in P 3.4 0.007433345 2.1 595 30 34 36 98 92 102 N N N N N N NDUFV3 high in P 6.7 0.007467439 2.1 596 164 56 72 1182 1005 334 N N N N N N LXN high in P 8.8 0.007474258 2.1 597 9 17 6 68 40 56 N N N N N N RBM15B high in P 4.3 0.007481077 2.1 598 117 199 118 765 647 571 N N N N N N TRMT2A high in P 4.2 0.007487896 2.1 599 9 44 25 122 133 94 N N N N N N PSMD1 high in P 5.9 0.007494715 2.1 600 282 460 664 5035 2790 1741 N N N N N N LOC344967 high in P 7.5 0.007540402 2.1 601 169 51 69 425 517 480 NA NA N N N N THAP4 high in P 6.9 0.007547221 2.1 602 409 135 235 1542 1652 997 N N N N N N PSKH1 high in P 4.4 0.00755404 2.1 603 11 30 23 69 73 82 N N N N N N ERCC8 high in P 5.3 0.007569042 2.1 604 6 6 6 15 23 18 N N N N N N ZNF623 high in P 6.3 0.007609274 2.1 605 21 7 9 53 37 69 N N N N N N SNX8 high in P 8.0 0.007616093 2.1 606 45 65 150 629 511 317 N N N N N N LOC284578 high in P 8.0 0.007629731 2.1 607 13 15 15 133 39 47 NA NA N N N N PRRG2 high in P 10.3 0.007653597 2.1 608 2 8 19 42 114 80 N N N N N N TUBB2C high in P 5.8 0.007693829 2.1 609 1698 2331 2731 6216 13417 15417 N N N N N N CKB high in P 8.1 0.007714286 2.1 610 664 255 829 2078 5123 6352 N N N N N N C14orf182 high in P 9.9 0.007734743 2.1 611 12 6 6 19 44 24 NA NA N N N N NCRNA00085 high in P 5.1 0.00774838 2.1 612 21 12 11 23 38 42 N N N N N N TSG101 high in P 5.8 0.007755199 2.1 613 319 177 338 4256 1757 935 N N N N N N HPS6 high in P 4.1 0.007768837 2.1 614 32 34 29 191 106 76 N N N N N N ADAT3 high in P 5.8 0.007775656 2.1 615 109 27 118 484 642 600 N N N N N N C6orf1 high in P 4.4 0.007782475 2.1 616 50 32 41 246 208 110 N N N N N N EDNRB high in P 4.6 0.007802932 2.1 617 3549 2410 3053 30925 10365 12704 N N N N N N ATP6V0D2 high in P 3.9 0.007823389 2.1 618 114 65 126 378 387 377 N N N N N N DISP1 high in P 3.1 0.007843846 2.1 619 49 44 47 127 141 131 N N N N N N C15orf17 high in P 4.1 0.007862939 2.1 620 132 86 90 347 531 439 N N N N N N PPP1R3F high in P 6.3 0.007888851 2.1 621 98 35 50 452 220 284 P P N N N N PLD6 high in P 8.3 0.007909308 2.1 622 36 15 15 114 116 142 N N N N N N NELF high in P 4.8 0.007962496 2.1 623 235 282 496 1365 1751 1114 N N N N N N SGIP1 high in P 4.8 0.007969315 2.1 624 20 19 9 73 44 71 N N N N N N HMX3 high in P 6.9 0.007989772 2.1 625 7 1 2 25 14 9 P P N N N N GPR25 high in P 5.3 0.007996591 2.1 626 22 6 12 34 65 83 P P N N N N PPM1D high in P 8.8 0.008025912 2.1 627 48 22 15 138 123 419 N N N N N N KPNB1 high in P 3.6 0.008046369 2.1 628 476 474 585 1483 2171 1740 N N N N N N EIF2B4 high in P 3.5 0.008073645 2.1 629 95 137 99 458 412 323 N N N N N N C17orf63 high in P 5.0 0.008080464 2.1 630 92 90 118 604 675 310 N N N N N N CHEK1 high in P 4.7 0.008100921 2.1 631 29 16 25 62 107 75 N N N N N N TM2D2 high in P 4.7 0.008114558 2.1 632 51 33 54 262 191 137 N N N N N N PIGL high in P 4.6 0.008128196 2.1 633 41 15 26 110 86 110 N N N N P N POP1 high in P 10.7 0.008177975 2.1 634 13 13 14 47 81 42 N N N N N N SLC4A3 high in P 10.5 0.008184794 2.1 635 70 18 17 119 330 189 N N N N N N FAAH high in P 7.0 0.008191613 2.1 636 17 16 28 56 70 59 N N N N N N RBM39 high in P 6.4 0.008225707 2.1 637 667 997 697 4293 2312 6218 N N N N N N RFXANK high in P 4.8 0.008232526 2.1 638 151 62 97 729 447 371 N N N N N N PROCA1 high in P 5.4 0.008239345 2.1 639 3 3 4 15 8 14 N N N N N N LOC283663 high in P 10.6 0.008246164 2.1 640 6 7 37 149 87 268 N N N N N N LAMA4 high in P 5.2 0.008281623 2.1 641 1660 465 1265 7394 4865 6145 N N N N N N MAP7D1 high in P 5.0 0.00830208 2.1 642 1285 606 2301 6853 9335 6496 N N N N N N ARHGAP11A high in P 4.3 0.008308899 2.1 643 8 13 10 44 29 26 N N N N N N MAGEA1 high in P 4.7 0.008315718 2.1 644 2 2 2 6 7 5 P P N N N N C2orf52 high in P 7.5 0.008329356 2.1 645 4 8 10 52 51 27 N N N N N N CUL2 high in P 3.5 0.008336175 2.1 646 74 56 68 187 212 207 N N N N N N TP53I13 high in P 5.0 0.008391408 2.1 647 132 57 203 978 548 639 N N N N N N IRF2BP1 high in P 5.1 0.008411865 2.1 648 114 37 83 422 457 317 N N N N N N DDN high in P 7.1 0.008432322 2.1 649 3 3 4 9 21 28 P N N P N P MMP17 high in P 6.4 0.008448005 2.1 650 6 10 31 95 65 77 N N N N N N ZDHHC14 high in P 3.8 0.008461643 2.1 651 168 139 116 418 618 529 N N N N N N MMEL1 high in P 7.6 0.008468462 2.1 652 4 4 7 25 41 15 P P N N N N TUBE1 high in P 5.2 0.008475281 2.1 653 25 36 39 262 186 92 N N N N N N VILL high in P 5.8 0.008488919 2.1 654 39 17 21 98 67 142 N N N N N N PBX4 high in P 9.0 0.008495738 2.1 655 92 27 34 695 160 910 N N N N N N REPIN1 high in P 12.7 0.008502557 2.1 656 439 76 117 1578 1633 922 N N N N N N OVGP1 high in P 8.7 0.008516195 2.1 657 17 15 13 23 62 57 N P N N N N PELI3 high in P 5.9 0.008523014 2.1 658 38 20 32 212 102 87 N N N N N N APOL3 high in P 6.8 0.008529833 2.1 659 136 32 104 998 509 443 N N N N N N SCARF1 high in P 8.8 0.008536652 2.1 660 19 8 12 47 76 79 N N N N N N PPP2CB high in P 3.9 0.008543471 2.1 661 1814 2047 2552 5778 7211 9626 N N N N N N HEBP2 high in P 5.0 0.008557109 2.1 662 44 25 29 211 196 82 N N N N P N MUDENG high in P 4.1 0.008563928 2.1 663 12 18 10 59 43 41 NA NA N N N N ZNF496 high in P 4.0 0.008570747 2.1 664 57 23 35 145 133 169 N N N N N N FOXD1 high in P 6.8 0.008584385 2.1 665 9 6 3 32 14 80 P P N N N N GVIN1 high in P 5.8 0.008591204 2.1 666 6 6 6 10 11 17 N N N N N N PNCK high in P 7.9 0.008620525 2.1 667 4 4 4 8 11 31 N P N N N N SEC31A high in P 5.3 0.008627344 2.1 668 1213 514 656 4684 3455 3076 N N N N P N HIRA high in P 4.6 0.008634163 2.1 669 69 50 51 184 311 224 N N N N N N C11orf84 high in P 8.9 0.008640982 2.1 670 104 55 112 900 285 2057 N N N N N N ENDOG high in P 4.1 0.00865462 2.1 671 107 62 83 329 362 228 N N N N N N TIMM17A high in P 4.2 0.008690078 2.1 672 576 391 569 2474 2770 1589 N N N N N N DGCR8 high in P 4.2 0.008696897 2.1 673 89 92 105 436 641 270 N N N N N N VMO1 high in P 10.7 0.008724173 2.1 674 2 3 7 59 13 72 P N N N N N LRCH1 high in P 4.8 0.008737811 2.1 675 362 204 285 986 1175 1939 N N N N N N PREX2 high in P 6.6 0.008751449 2.1 676 13 13 17 38 34 67 N N N N N N GSDMA high in P 3.0 0.008758268 2.1 677 56 49 53 134 119 138 N N N N N N PSORS1C3 high in P 5.5 0.008765087 2.1 678 13 2 3 11 22 14 NA NA N N N N C4orf42 high in P 3.9 0.008771906 2.1 679 NA NA NA NA NA NA N N N N N N SP4 high in P 4.9 0.008778725 2.1 680 46 35 24 136 125 243 N N N N N N BAZ1B high in P 4.4 0.008792363 2.1 681 134 134 245 694 858 1033 N N N N N N RDH5 high in P 5.1 0.008799182 2.1 682 76 17 43 232 178 200 N N N N N N EIF4G3 high in P 3.8 0.008818957 2.1 683 30 46 40 99 111 140 N N N N N N MRPS18C high in P 9.4 0.008832595 2.1 684 4 33 11 153 106 79 N N N N N N MAP4K4 high in P 3.9 0.008853051 2.1 685 370 575 757 2458 2288 3270 N N N N N N FOXD2 high in P 8.8 0.008875554 2.1 686 3 4 6 38 12 56 P N N N N N ANKFY1 high in P 9.3 0.008882373 2.1 687 137 38 58 564 465 411 N N N N N N LOC728606 high in P 4.7 0.008889192 2.1 688 7 20 19 51 62 83 N P N N N N LOC652276 high in P 4.2 0.00890283 2.1 689 17 22 12 67 55 71 N N N N N N FRG2 high in P 4.5 0.008916468 2.0 690 3 4 3 13 8 11 P P N N N N REL high in P 6.3 0.008930106 2.0 691 498 190 216 1543 1167 3314 N N N N N N ZNF563 high in P 5.3 0.00894238 2.0 692 19 9 9 21 24 42 N N N N N N UTS2D high in P 4.7 0.008949199 2.0 693 7 10 17 52 25 55 N N N N N N SEC31B high in P 5.9 0.008956018 2.0 694 33 22 28 101 95 124 N N N N N N LOC100128675 high in P 5.2 0.008968974 2.0 695 11 12 19 54 39 52 NA NA N N N N COG1 high in P 4.9 0.008975793 2.0 696 85 29 47 324 193 188 N N N N N P KIAA1984 high in P 8.2 0.008989431 2.0 697 6 8 16 28 58 40 N P N N N N SP9 high in P 8.6 0.00899625 2.0 698 8 3 10 26 22 72 NA NA N N N N PEX16 high in P 5.1 0.009003069 2.0 699 61 59 94 558 389 212 N N N N N N TMEM53 high in P 5.5 0.009059666 2.0 700 69 20 94 385 464 339 N N N N N N SCAND2 high in P 3.8 0.009082168 2.0 701 37 43 66 192 234 203 N N N N N N CCDC24 high in P 6.0 0.009094443 2.0 702 14 4 6 39 59 15 N N N N N N NAP1L4 high in P 6.8 0.009101262 2.0 703 723 350 1703 3828 6504 4906 N N N N N N INCENP high in P 4.5 0.009114899 2.0 704 18 9 10 35 54 39 N N N N N N C16orf68 high in P 5.8 0.009128537 2.0 705 52 38 98 363 305 188 N N N N N N TMOD1 high in P 7.2 0.009135356 2.0 706 29 27 41 491 246 95 N N N N N N OSBPL7 high in P 6.7 0.00914763 2.0 707 36 11 26 126 116 282 N N N N N N RBM41 high in P 7.1 0.009173542 2.0 708 2 2 2 8 12 5 P P N N N N MS4A7 high in P 4.1 0.009180361 2.0 709 35 33 57 153 117 136 N N N N N N CD40 high in P 7.3 0.009192636 2.0 710 237 118 40 1319 606 872 N N N N N N GMFG high in P 12.5 0.009199454 2.0 711 34 2 54 509 205 340 N N N N N N ALPP high in P 4.6 0.009206273 2.0 712 324 178 315 827 1185 1490 N P N N N N ZNF765 high in P 4.5 0.009219911 2.0 713 46 40 56 161 329 126 N N N N N N RNH1 high in P 5.3 0.009233549 2.0 714 1167 601 809 7645 4037 2701 N N N N N N ALKBH6 high in P 4.6 0.009250597 2.0 715 27 15 12 66 68 42 N N N N N N RASA2 high in P 5.1 0.009257416 2.0 716 6 6 6 16 16 24 N N N N P N APOA1 high in P 9.9 0.009267644 2.0 717 22 5 7 24 92 136 N N N N N N CIB2 high in P 9.5 0.009325605 2.0 718 129 9 45 431 381 665 N N N N N N BEGAIN high in P 6.8 0.009352881 2.0 719 39 50 55 125 373 327 N N P N N N UBE4B high in P 4.0 0.009368565 2.0 720 366 159 307 1089 1487 1212 N N N N N N ARF1 high in P 4.0 0.009380839 2.0 721 7338 4258 7770 37639 23386 20252 N N N N N N GNAL high in P 7.9 0.009387658 2.0 722 6 6 7 14 14 45 N N N P N N MVK high in P 5.2 0.009429935 2.0 723 27 23 55 199 138 93 N N N N N N REXO2 high in P 2.9 0.009436754 2.0 724 389 322 373 1093 1081 979 N N N N N N TNFRSF6B high in P 6.0 0.009457211 2.0 725 76 18 64 362 402 170 N N N N N N DIO3 high in P 8.0 0.009472895 2.0 726 11 5 6 16 18 37 N N P N P N EPR1 high in P 16.2 0.009479714 2.0 727 34 3 23 57 325 446 N N N N N N MCM7 high in P 4.6 0.009505626 2.0 728 160 136 199 470 749 1183 N N N N N P PPP2R3B high in P 5.2 0.0095179 2.0 729 23 8 24 55 72 102 N N N N N N FAM178A high in P 3.8 0.009542448 2.0 730 28 30 32 95 61 95 N N N N N N SFRS13B high in P 4.9 0.009573133 2.0 731 6 6 7 28 22 21 NA NA N N N N ZBTB39 high in P 4.3 0.009579952 2.0 732 14 20 23 94 60 51 N N N N N N HTR3B high in P 11.0 0.009586771 2.0 733 114 6 31 288 339 430 P P N N N N B3GAT3 high in P 7.2 0.00959359 2.0 734 144 47 58 490 548 330 N N N N N N NES high in P 8.1 0.009638595 2.0 735 653 204 560 1452 5263 5161 N N N N N N TGFB1I1 high in P 10.4 0.009645414 2.0 736 1179 125 587 6602 5731 3015 N N N N N N NFE2L1 high in P 10.5 0.009652233 2.0 737 766 156 524 8888 2921 2172 N N N N N N ZNF208 high in P 3.2 0.009659052 2.0 738 19 29 30 66 73 53 N N N N N N GPATCH3 high in P 11.1 0.009665871 2.0 739 23 25 96 289 256 195 N N N N N N ZNF579 high in P 3.3 0.00967269 2.0 740 43 55 48 133 171 145 N N N N N N SIDT2 high in P 4.8 0.009679509 2.0 741 129 61 78 377 320 582 N N N N N N SGTA high in P 11.9 0.009686328 2.0 742 339 24 792 2996 3949 7198 N N N N N N TFIP11 high in P 3.5 0.009698602 2.0 743 102 173 132 455 421 363 N N N N P N CARD6 high in P 3.1 0.009705421 2.0 744 391 319 442 1218 1048 1230 N N N N N N ZNF525 high in P 3.8 0.009719059 2.0 745 31 26 27 73 132 86 N N N N N N CCDC57 high in P 4.5 0.009725878 2.0 746 59 43 73 171 278 171 N N N N N N C3orf42 high in P 6.6 0.009739516 2.0 747 3 8 35 55 94 113 NA NA N N N N TTC21A high in P 7.1 0.009766792 2.0 748 4 4 6 10 17 24 N N N N N N TECR high in P 5.9 0.009773611 2.0 749 640 200 286 1675 1849 1641 NA NA N N N N SPSB3 high in P 13.2 0.00978043 2.0 750 345 96 10 1258 976 2140 N N N N N N ALKBH4 high in P 6.4 0.009787249 2.0 751 441 89 214 1510 1261 1329 N N N N N N TMEM176A high in P 5.3 0.009815888 2.0 752 6 8 6 26 22 45 N N N N N N DAZAP2 high in P 4.4 0.009822707 2.0 753 1770 1069 1239 9567 4655 4250 N N N N N N CCDC146 high in P 3.8 0.009829526 2.0 754 6 8 15 39 27 31 N N N N N N PQLC2 high in P 7.2 0.00984521 2.0 755 2 2 6 21 27 13 N N N N N N SESN1 high in P 6.3 0.009852029 2.0 756 140 79 46 613 261 626 N N N N N N TTL high in P 3.9 0.009858848 2.0 757 97 43 89 344 326 300 N N N N N N GABBR1 high in P 4.2 0.009888169 2.0 758 203 141 248 730 608 893 N N N N N N ZNF70 high in P 4.1 0.009898398 2.0 759 6 11 8 24 32 21 N N N N N N SNORD34 high in P 13.5 0.00994954 2.0 760 2 3 10 17 53 56 N N N N N N BCL2L11 high in P 4.7 0.009965223 2.0 761 467 286 539 1701 1423 2633 N N N N N N MBOAT2 high in P 4.2 0.009978861 2.0 762 75 46 39 182 190 171 N N N N N N RNF217 high in P 9.5 0.00998568 2.0 763 4 7 5 12 53 52 N N N N N N TBP high in P 4.5 0.009992499 2.0 764 33 29 55 213 194 122 N N N N N N C6orf120 high in P 8.5 0.01002523 2.0 765 119 33 45 361 382 377 N N N N N N TRPV1 high in P 4.4 0.010040914 2.0 766 6 7 9 17 34 26 N N N N N N KHNYN high in P 4.3 0.010047733 2.0 767 171 93 266 776 1049 881 NA NA N N N N PRELID1 high in P 4.2 0.010054552 2.0 768 85 92 100 347 407 205 N N N N N N RPS11 high in P 6.8 0.010075009 2.0 769 32527 10403 13181 193390 127672 78612 N N N N N N CCDC55 high in P 3.2 0.010095465 2.0 770 181 216 221 638 696 902 N N N N N N ZNF335 high in P 4.8 0.010115922 2.0 771 89 76 187 444 509 429 N N N N N N LYSMD2 high in P 4.9 0.010131606 2.0 772 25 19 19 86 117 42 N N N N N N KIAA0467 high in P 3.5 0.010166383 2.0 773 47 43 55 147 114 108 N N N N N N ERAL1 high in P 5.2 0.01018002 2.0 774 24 45 31 336 150 90 N N N N N N PDE4D high in P 4.0 0.010193658 2.0 775 51 92 65 351 215 419 N N N N N N TIMM13 high in P 5.5 0.010200477 2.0 776 321 231 610 1775 3123 1348 N N N N N N COMMD2 high in P 4.8 0.010235254 2.0 777 14 5 6 29 28 14 N N N N N N MPPE1 high in P 5.8 0.010255711 2.0 778 24 13 39 84 128 132 N N N N P N SLC22A9 high in P 15.4 0.010274804 2.0 779 3 3 3 6 21 19 N N N N N N PHF20 high in P 4.7 0.010293897 2.0 780 147 108 65 710 504 471 N N N N N N IQCE high in P 9.0 0.010345721 2.0 781 43 18 21 117 126 116 N N N N N N C2orf14 high in P 6.7 0.01035254 2.0 782 8 23 28 104 138 156 N N N N N N MCM2 high in P 5.9 0.010366178 2.0 783 45 15 34 189 118 78 N N N N N N RC3H2 high in P 4.3 0.010405046 2.0 784 23 60 87 262 203 301 N N N N N N SYNGR3 high in P 8.5 0.010434368 2.0 785 3 4 6 15 17 49 N N N N N N SLC2A8 high in P 5.9 0.010456188 2.0 786 47 12 23 113 146 108 N N N N P N PAPPA high in P 7.0 0.010463007 2.0 787 120 293 121 4321 1168 762 N N N N N N SLC6A7 high in P 4.9 0.010469826 2.0 788 6 6 7 10 18 14 N N N N N N ATRIP high in P 5.1 0.010476645 2.0 789 53 10 35 165 216 117 N N N N N N WDHD1 high in P 7.2 0.010483464 2.0 790 8 8 8 27 11 21 N N N N N N E2F4 high in P 4.8 0.010490283 2.0 791 4 9 18 59 100 36 N N N N N N SHROOM2 high in P 5.6 0.010497102 2.0 792 6 7 9 22 33 17 P P N N N N PARG high in P 4.4 0.010528469 2.0 793 20 23 17 87 44 96 N N N N N N MFSD5 high in P 3.2 0.010535288 2.0 794 91 82 85 354 257 212 N N N N N P SNRNP25 high in P 6.3 0.010542107 2.0 795 46 9 14 76 96 66 N N N N N N FLJ10213 high in P 5.7 0.010562564 2.0 796 3 3 3 16 6 16 N N N N N N LTB4R high in P 6.4 0.010569383 2.0 797 13 16 22 87 70 29 N N N N N N GYS1 high in P 7.1 0.010583021 2.0 798 50 75 218 1095 681 356 N N N N N N UGGT2 high in P 6.1 0.010647119 2.0 799 29 21 44 249 161 60 NA NA N N N N TRAF4 high in P 5.0 0.010667576 2.0 800 1125 559 1098 2791 8537 5085 N N N N N N ST20 high in P 5.2 0.010681214 2.0 801 2 2 2 6 9 12 N N N N N N LOC283731 high in P 8.3 0.010688033 2.0 802 8 2 4 9 18 34 NA NA N N N N KLC1 high in P 6.7 0.010713263 2.0 803 454 235 889 3478 3374 2015 N N N N N N PTRH1 high in P 5.3 0.010741221 2.0 804 42 70 113 448 523 192 N N N N N N WDR5 high in P 4.6 0.010765769 2.0 805 17 37 28 127 150 61 N N N N N N FIBP high in P 4.2 0.010784862 2.0 806 119 44 150 616 455 388 N N N N N N ZC3H12B high in P 5.6 0.010838732 2.0 807 9 11 11 32 21 62 N P N N N N C19orf44 high in P 4.0 0.01085237 2.0 808 20 15 23 72 41 57 N N N N N N USP35 high in P 3.2 0.01088851 2.0 809 6 8 9 20 16 24 N N N N N N MRPL12 high in P 6.3 0.010917832 2.0 810 204 157 144 1101 1159 371 N N N N N N MCOLN2 high in P 8.9 0.010924651 2.0 811 63 20 49 177 222 636 N P N N N N DNER high in P 4.5 0.010938288 2.0 812 7 17 35 108 68 64 P P N N N N ALG3 high in P 4.2 0.010957382 2.0 813 229 115 137 1015 905 425 N N N N N N MKLN1 high in P 3.9 0.0109642 2.0 814 229 165 271 713 936 1341 N N N N N N ZGLP1 high in P 4.4 0.010976475 2.0 815 10 5 6 12 17 25 NA NA N N N N IDUA high in P 5.2 0.010983294 2.0 816 141 68 101 307 510 1063 N N N N N N RAB17 high in P 3.7 0.010990113 2.0 817 6 8 10 22 28 21 N N N N N N WFIKKN1 high in P 6.8 0.01100375 2.0 818 5 8 7 15 40 69 N N N N N N CCDC93 high in P 3.4 0.011017388 2.0 819 24 35 38 84 102 102 N N N N N N CD58 high in P 3.7 0.011037845 2.0 820 16 23 15 56 43 79 N N N N N N COG2 high in P 6.2 0.011044664 2.0 821 27 15 21 144 105 38 N P N N N N DKFZp761E198 high in P 4.0 0.011058302 2.0 822 101 125 176 1155 519 501 N P N N N N ACP1 high in P 6.0 0.011065121 2.0 823 60 34 80 395 620 157 N N N N N N ZC3H7B high in P 6.1 0.011088305 2.0 824 77 43 51 290 208 183 N N N N N N NCRNA00169 high in P 5.4 0.011127855 2.0 825 6 8 11 22 23 35 NA NA N N N N CDKN2A high in P 6.5 0.011143539 2.0 826 122 31 43 431 208 256 P P N N N N ZC3H18 high in P 3.3 0.011150358 2.0 827 74 40 53 166 165 200 N N N N N N HSPBP1 high in P 4.5 0.011157177 2.0 828 126 88 84 1031 322 353 N N N N N N OPLAH high in P 3.9 0.011169451 2.0 829 112 47 110 386 372 302 N N N N N N QPCTL high in P 5.6 0.011183089 2.0 830 3 3 4 34 13 11 N N N N N N DDTL high in P 6.1 0.011196727 2.0 831 9 18 35 74 140 78 N N N N N N SNORA24 high in P 5.4 0.011206955 2.0 832 1 1 1 3 6 9 N N N N N N PLB1 high in P 5.4 0.011206955 2.0 833 7 7 7 9 12 15 N N N N N N CBS high in P 10.0 0.011226048 1.9 834 34 26 9 235 320 52 P N N N N N WAS high in P 7.5 0.011232867 1.9 835 3 9 6 24 22 142 P P N N N N SNORA80B high in P 7.9 0.011239686 1.9 836 1 4 1 12 23 9 NA NA N N N N POLA1 high in P 6.2 0.011246505 1.9 837 9 9 11 69 19 27 N N N N N N ZNF484 high in P 4.9 0.011260143 1.9 838 4 4 4 15 11 7 N N N N N N TTLL4 high in P 4.6 0.011266962 1.9 839 46 110 184 463 678 433 N N N N N N C7orf63 high in P 5.3 0.011273781 1.9 840 13 16 25 70 40 44 N N N N N N RAB2B high in P 3.6 0.0112806 1.9 841 35 25 37 115 88 119 N N N N N N ZNF490 high in P 5.7 0.011287419 1.9 842 28 17 22 74 133 146 N N N N N N HUWE1 high in P 2.8 0.011294238 1.9 843 176 222 204 576 602 627 N N N N N N NNT high in P 3.3 0.011301057 1.9 844 9 10 12 28 23 20 N N N N N N FRG1 high in P 4.6 0.011328333 1.9 845 29 46 18 147 132 71 N N N N N N CARS high in P 6.7 0.011335152 1.9 846 294 172 318 2088 1976 642 N N N N N N C2orf60 high in P 5.2 0.01134879 1.9 847 37 20 19 101 66 78 N N N N N N YRDC high in P 3.5 0.011355609 1.9 848 83 44 68 251 205 156 N N N N P N PSENEN high in P 4.0 0.011369247 1.9 849 189 189 142 817 697 396 N N N N N N CES3 high in P 5.8 0.011384248 1.9 850 10 15 11 27 56 67 N N N N N N SCN11A high in P 4.9 0.011391067 1.9 851 40 18 22 101 86 63 N N N N N N PMS2 high in P 3.6 0.011442891 1.9 852 39 36 53 114 164 106 N N N N N P APOBEC3G high in P 5.9 0.011456529 1.9 853 19 17 10 35 86 201 N N N N N N FZD5 high in P 5.3 0.011521309 1.9 854 75 70 123 251 447 768 N N N N N N SPATA5L1 high in P 4.3 0.011533583 1.9 855 23 15 28 51 85 57 N N N N N N CRTC2 high in P 4.3 0.011555404 1.9 856 45 96 137 421 347 594 N N N N N N ITGB5 high in P 6.7 0.011562223 1.9 857 2795 822 2029 18375 12811 5593 N N N N N N BET1L high in P 4.2 0.011575179 1.9 858 34 28 32 200 82 96 N N N N N N BMS1 high in P 4.3 0.011588817 1.9 859 57 43 85 240 287 196 N P N N N N REV1 high in P 3.7 0.011595636 1.9 860 76 74 72 198 344 330 N N N N N N FCHSD1 high in P 3.9 0.011609274 1.9 861 7 13 18 60 40 84 N N N N N N CHMP4A high in P 4.5 0.011622912 1.9 862 69 24 57 299 169 175 N N N N N N SHROOM1 high in P 6.7 0.01163655 1.9 863 52 15 29 178 170 98 N N N N N N MRPL41 high in P 8.8 0.011650188 1.9 864 129 63 349 1125 1043 599 N N N N N N C20orf200 high in P 8.4 0.011699284 1.9 865 NA NA NA NA NA NA P P N N N N APOOL high in P 3.7 0.011728606 1.9 866 66 41 55 178 110 201 N N N N N N APEH high in P 7.0 0.011749062 1.9 867 262 48 133 1195 892 507 N N N N N N RBM44 high in P 7.6 0.011755881 1.9 868 7 14 7 28 35 20 N N N N N N ALG13 high in P 6.0 0.011769519 1.9 869 3 7 17 40 67 28 N N N N N N C9orf114 high in P 5.1 0.011776338 1.9 870 8 14 18 102 60 31 N N N N N N TRIM26 high in P 3.6 0.011810433 1.9 871 342 190 392 940 1189 1328 N N N N N N MYO10 high in P 5.7 0.011817252 1.9 872 265 127 152 625 864 864 N N N N N N C1orf163 high in P 4.2 0.011836345 1.9 873 6 18 24 67 80 52 N N N N N N WDR54 high in P 6.9 0.011843164 1.9 874 26 7 14 161 47 51 N N N N N N HLA-B high in P 4.2 0.011849983 1.9 875 14413 5271 7525 49708 27420 32526 N N N N N N S100A7 high in P 8.7 0.011863621 1.9 876 1 14 37 143 264 94 N N N N N N SLC25A38 high in P 3.5 0.011877259 1.9 877 148 125 63 419 506 368 N P N N N N ANKMY1 high in P 8.0 0.011884078 1.9 878 20 13 16 94 65 24 N N N N N N MUC16 high in P 10.1 0.011890897 1.9 879 51 55 51 74 232 104 P N N N N N DNAI2 high in P 8.9 0.011897716 1.9 880 3 3 4 11 12 201 N N N N N N BCKDK high in P 4.5 0.011911354 1.9 881 285 173 304 1815 1012 730 N N N N N N LOC100130776 high in P 6.6 0.011924991 1.9 882 9 14 27 92 83 55 NA NA N N N N KIAA0368 high in P 4.1 0.011945448 1.9 883 297 392 715 1427 1730 2335 N N N N N N INCA1 high in P 7.3 0.011972724 1.9 884 14 3 4 9 32 24 N N N N N N ISM2 high in P 5.8 0.011993181 1.9 885 9 2 3 7 19 23 NA NA N N N N PDHA1 high in P 3.2 0.012 1.9 886 182 170 170 751 599 453 N N N N N N LOC286467 high in P 5.6 0.012006819 1.9 887 6 22 34 73 115 109 NA NA N N N N BLOC1S1 high in P 5.2 0.012013638 1.9 888 350 168 326 1765 1085 781 N N N N N N TMED10P high in P 4.5 0.012020457 1.9 889 NA NA NA NA NA NA N N N N N N GPR133 high in P 5.3 0.012027276 1.9 890 24 24 46 226 84 160 N N N N N N C8orf80 high in P 3.5 0.012034095 1.9 891 16 35 32 106 66 94 N P N N N N RPS6KA4 high in P 4.9 0.012040914 1.9 892 102 55 203 489 691 436 N N N N N N QTRT1 high in P 4.5 0.012047733 1.9 893 114 79 226 581 478 674 N N N N N N PNPLA2 high in P 4.0 0.012054552 1.9 894 493 237 313 1152 1839 1399 N N N N N N MRPL20 high in P 4.2 0.012090692 1.9 895 22 72 43 210 298 144 N N N N N N AP4S1 high in P 4.3 0.012097511 1.9 896 171 218 173 484 715 1440 N N N N N N C22orf30 high in P 5.1 0.012151381 1.9 897 20 28 36 177 108 53 N N N P N N C1orf135 high in P 5.4 0.0121582 1.9 898 903 597 1820 4926 5020 3504 N N N N N N SLC17A9 high in P 4.5 0.012165019 1.9 899 9 11 12 31 37 25 NA NA N N N N SIRT3 high in P 3.3 0.012192295 1.9 900 1164 705 1455 3839 4001 3212 N N N N N N PTPN6 high in P 12.5 0.012205932 1.9 901 54 9 14 79 127 207 N N N N N N CWF19L1 high in P 4.9 0.012240027 1.9 902 26 15 13 99 70 47 N N N N N N ERI3 high in P 5.7 0.012304125 1.9 903 242 87 206 1360 954 475 NA NA N N N N CEACAM5 high in P 3.4 0.012310944 1.9 904 241 146 283 697 696 895 P P N N N N KRTCAP3 high in P 5.0 0.012330038 1.9 905 8 7 2 14 49 19 N N N N N N APEX2 high in P 7.4 0.012336856 1.9 906 74 16 35 270 222 103 P N N N N N PDDC1 high in P 3.7 0.012359359 1.9 907 16 28 30 88 98 131 N N N N N N BIRC5 high in P 7.9 0.012375043 1.9 908 7 7 9 13 40 57 N N N N N N ZNF662 high in P 3.0 0.012433686 1.9 909 18 24 16 47 46 51 N N N N N N INO80 high in P 3.7 0.012461643 1.9 910 107 76 134 472 301 338 N N N N N N UBE3C high in P 4.3 0.012468462 1.9 911 271 167 250 1035 1299 585 N N N N N P MAST2 high in P 5.8 0.012520968 1.9 912 288 144 510 1118 1302 3016 N N N N N N SETMAR high in P 3.6 0.012527787 1.9 913 16 26 24 63 70 48 N N N N N N MLH1 high in P 4.6 0.012534606 1.9 914 21 8 8 62 23 39 N N N N N N IKZF2 high in P 4.0 0.012551654 1.9 915 19 33 23 53 68 135 N N N N N N LILRB1 high in P 3.6 0.012558473 1.9 916 55 35 49 120 111 164 N N N N N N DDX19A high in P 4.3 0.012578929 1.9 917 6 7 7 17 11 21 N N N N N N FKBPL high in P 6.4 0.012592567 1.9 918 42 11 10 55 81 120 N N N N N N XPC high in P 5.6 0.012613024 1.9 919 123 47 54 627 233 263 N N N N N N KDM4D high in P 9.5 0.012639618 1.9 920 24 6 7 35 22 47 NA NA N N N N GIT1 high in P 6.3 0.012670985 1.9 921 72 18 47 245 271 279 N N N N N N TPRKB high in P 4.3 0.012683259 1.9 922 57 49 81 345 236 136 N N N N N N ERMP1 high in P 11.8 0.012690078 1.9 923 31 15 17 75 89 49 N N N N P N MFSD9 high in P 11.4 0.012696897 1.9 924 13 13 13 50 40 16 N N N N N N FAU high in P 3.0 0.012703716 1.9 925 9780 6709 12149 27418 30489 27432 N N N N N N NXPH4 high in P 5.6 0.012730992 1.9 926 11 6 10 20 36 18 N P N N N N NCRNA00105 high in P 13.2 0.012737811 1.9 927 17 12 19 28 193 220 NA NA N N N N FOXF2 high in P 5.0 0.012767133 1.9 928 146 119 149 721 319 1167 P N N N N N PMF1 high in P 5.4 0.012773952 1.9 929 198 84 79 474 513 392 N N N N N N UBE2J1 high in P 3.9 0.012780771 1.9 930 506 308 304 2581 1384 1282 N N N N N N FOXC2 high in P 4.2 0.012808728 1.9 931 20 17 50 160 189 66 P P N N N N KCTD2 high in P 2.7 0.012846914 1.9 932 112 103 111 303 314 261 N N N N N N UBA5 high in P 3.7 0.012860552 1.9 933 117 74 74 440 316 212 N N N N N N TAT high in P 5.0 0.012889874 1.9 934 163 39 76 371 361 402 N N N N N N SCNN1D high in P 5.9 0.012902148 1.9 935 31 11 18 38 91 125 N N N N N N DOT1L high in P 4.9 0.012922605 1.9 936 572 321 1116 3072 3245 2614 N N N N N N KRTAP2-4 high in P 7.9 0.012929424 1.9 937 1 1 1 3 21 9 N P N N N N TMUB1 high in P 4.8 0.012945107 1.9 938 160 38 239 1040 765 579 N N N N N N BPNT1 high in P 3.5 0.012951926 1.9 939 2506 1758 1852 8708 5450 5960 N N N N N N FKSG83 high in P 5.2 0.012979202 1.9 940 2 2 2 6 4 12 N P N N N N CDK16 high in P 3.7 0.012986021 1.9 941 977 315 750 3024 3235 2814 NA NA N N N N PDE4C high in P 8.8 0.01299284 1.9 942 17 17 19 108 72 137 P P N N N N LDLR high in P 6.7 0.013026935 1.9 943 2243 594 1273 9193 10636 3798 N N N P N N RAB11FIP5 high in P 3.6 0.013033754 1.9 944 35 30 32 132 89 157 N N N N N N TCEB3 high in P 3.6 0.013047392 1.9 945 217 302 354 789 1561 1147 N N N N N P PLAGL2 high in P 3.3 0.013054211 1.9 946 189 284 184 648 923 692 N N N N N N WWTR1 high in P 6.3 0.013074668 1.9 947 519 196 411 1023 2585 4943 N N N N N N TMEM184B high in P 3.1 0.013091715 1.9 948 154 118 178 591 516 423 N N N N N N USP8 high in P 2.9 0.013103989 1.9 949 90 76 68 270 194 210 N N N N P N ACTL7B high in P 4.7 0.013117627 1.9 950 1 1 1 9 6 4 N N N N N N ANKLE1 high in P 3.8 0.013166042 1.9 951 46 56 32 155 96 184 N N N N N N CD3E high in P 21.5 0.01317968 1.9 952 59 2 4 63 123 680 N P N N N N ORC2L high in P 3.3 0.013186498 1.9 953 6 8 13 47 36 41 N N N N N N C17orf69 high in P 6.8 0.013200136 1.9 954 9 9 9 21 24 23 NA NA N N N N LOC644669 high in P 7.2 0.01326628 1.9 955 1 6 22 51 54 106 NA NA N N N N ECD high in P 3.8 0.013281964 1.9 956 156 135 261 521 586 619 N N N N N N IL10 high in P 5.1 0.013288783 1.9 957 97 31 54 196 227 469 N N N N N N SH2B2 high in P 4.8 0.013295602 1.9 958 50 13 41 108 166 232 N N P N N N MCM5 high in P 6.8 0.013302421 1.9 959 225 43 98 643 468 594 N N N N N N CECR7 high in P 4.0 0.013316059 1.9 960 9 12 16 27 27 57 N P N N N N TDRD7 high in P 4.0 0.013329697 1.9 961 15 13 12 50 23 37 P P N N N N ABI1 high in P 3.4 0.013355609 1.9 962 243 314 404 905 1404 1244 N N N N N N DOM3Z high in P 4.5 0.013362428 1.9 963 49 41 85 210 172 147 N N N N N N HDAC3 high in P 2.9 0.013376065 1.9 964 13 27 23 64 51 48 N N N N N N POLH high in P 2.8 0.013418343 1.9 965 74 136 109 376 336 453 N N N N N N PRDM7 high in P 6.3 0.013431981 1.9 966 8 8 8 18 21 24 N N N N N N RHCG high in P 4.1 0.0134388 1.9 967 6 22 11 79 28 67 P N N N N N ZNF167 high in P 11.1 0.013452438 1.9 968 12 6 6 28 26 9 P P N N N N AP1S1 high in P 6.0 0.013459257 1.9 969 79 21 21 296 129 104 P P N N N N DGCR11 high in P 4.3 0.013481077 1.9 970 6 7 10 28 15 23 N N N N N N RNPC3 high in P 3.3 0.013493352 1.9 971 7 14 17 43 38 38 N N N N N N GDAP1 high in P 6.3 0.013547221 1.9 972 30 14 9 62 54 43 N P N N P N RDBP high in P 6.2 0.013571088 1.9 973 281 136 74 1370 961 498 N N N N N N NCBP1 high in P 4.8 0.013577907 1.9 974 35 21 24 51 131 87 N N N N N N POU3F1 high in P 5.5 0.013598363 1.9 975 21 13 21 48 71 241 N P N N N N ATP6V0C high in P 4.1 0.013608592 1.9 976 2651 2197 4251 9050 12301 11753 N N N N N N C10orf140 high in P 7.6 0.013637232 1.9 977 10 10 11 53 26 51 N N N N N N DGKA high in P 4.5 0.01364405 1.9 978 83 19 55 181 202 264 N N N N N N TNFSF10 high in P 3.5 0.013669962 1.9 979 816 329 588 2004 1899 2455 N N N N N N PDLIM4 high in P 4.5 0.0136836 1.9 980 1187 899 1788 3993 9631 3740 N N N N P N EXOC6B high in P 4.5 0.013690419 1.9 981 8 8 8 18 11 14 N N N N N N IGSF21 high in P 15.0 0.013697238 1.9 982 2 2 3 19 7 85 P P N N N N RHBDL3 high in P 6.6 0.013779066 1.9 983 11 13 21 66 80 256 N N N N N N FST high in P 6.4 0.013809069 1.9 984 759 484 994 6757 5599 1692 N N N N N P S100A3 high in P 7.5 0.013822707 1.9 985 33 7 8 71 228 36 N N N N N N GOLGB1 high in P 3.5 0.013829526 1.9 986 136 141 191 737 366 732 N N N N N N DNAJB13 high in P 3.5 0.013862257 1.9 987 4 5 6 17 29 12 N N N P N N KTELC1 high in P 4.2 0.013869076 1.9 988 95 42 49 314 223 166 N N N N N N FERMT1 high in P 12.3 0.013875895 1.9 989 6 6 6 18 107 9 N N N N N N UPP2 high in P 5.6 0.013891579 1.9 990 5 34 44 86 166 170 N N N N N N TPRG1L high in P 4.2 0.013898398 1.9 991 317 151 257 1429 854 785 N N N N N N MIIP high in P 6.0 0.013905217 1.9 992 81 24 15 139 184 134 NA NA N N N N SPHK1 high in P 3.9 0.013919536 1.9 993 735 795 1581 2517 5576 4815 N N N N N N HAPLN2 high in P 4.7 0.013933174 1.9 994 1 1 1 11 6 4 N P N N N N OFD1 high in P 3.5 0.013953631 1.9 995 88 96 109 254 459 432 N N N N N N C20orf29 high in P 3.8 0.01396045 1.9 996 21 19 15 174 60 39 N N N N N N RUNDC2C high in P 4.2 0.013980907 1.9 997 23 26 29 43 92 96 N N N N N N VPS25 high in P 4.5 0.013987726 1.9 998 145 93 118 1134 508 285 N N N N N N SHOX2 high in P 4.6 0.013994545 1.9 999 141 89 91 516 274 844 N N N N N N ZFAT high in P 4.7 0.014008183 1.9 1000 19 19 16 81 31 51 N N N N N N E2F2 high in P 3.5 0.014057961 1.9 1001 6 7 10 31 20 19 N N N N N N SIRPB1 high in P 12.2 0.01406478 1.9 1002 19 2 3 18 31 35 N P N N N N DHX9 high in P 3.0 0.014103648 1.9 1003 223 315 362 810 787 985 N N N N N N USP32 high in P 4.7 0.014137061 1.8 1004 14 16 16 24 34 50 N N N N N N HAVCR2 high in P 6.3 0.01414388 1.8 1005 20 4 11 62 27 95 N N N N N N ILF3 high in P 3.8 0.014177975 1.8 1006 302 284 236 869 1389 1795 N N N N P N HIST1H1C high in P 29.7 0.014188203 1.8 1007 7 1 1 87 48 4 N N N N N N SRGAP2 high in P 4.3 0.014209342 1.8 1008 122 76 132 504 293 841 N N N N N N ZBTB40 high in P 4.3 0.01422298 1.8 1009 125 83 141 365 499 780 N N N N N N UNC45A high in P 4.1 0.014255711 1.8 1010 255 112 186 1091 566 579 N N N N N N KLHDC4 high in P 3.2 0.014295261 1.8 1011 13 13 18 29 54 34 N N N N N N CD22 high in P 4.2 0.014340948 1.8 1012 3 7 5 15 13 32 N N N N N N PEBP4 high in P 4.8 0.014377088 1.8 1013 18 2 8 28 36 45 N N P N N N CCDC86 high in P 3.2 0.014397545 1.8 1014 204 262 201 589 1219 634 N N N N N N AKT1 high in P 3.9 0.014409819 1.8 1015 578 302 602 2393 1652 1548 N N N N N P HDAC6 high in P 4.5 0.014430276 1.8 1016 86 44 84 220 219 411 P P N N N N MLXIPL high in P 3.4 0.014437095 1.8 1017 24 35 39 69 86 130 N N N N N N ALG12 high in P 4.6 0.014468462 1.8 1018 55 32 45 291 193 90 N N N N N N PSPH high in P 17.4 0.014490965 1.8 1019 27 6 6 45 47 31 N N N N P N RAVER2 high in P 6.0 0.014514149 1.8 1020 22 11 12 30 62 31 N N N N N N PCBD2 high in P 6.3 0.014541425 1.8 1021 58 22 26 167 143 190 N N N N N N CHD3 high in P 4.9 0.014548244 1.8 1022 473 128 284 1509 1028 2421 N N N N N N LOC100272228 high in P 4.7 0.014571429 1.8 1023 6 6 6 9 11 17 NA NA N N N N C10orf111 high in P 4.7 0.014571429 1.8 1024 4 4 4 6 9 15 N N N N N N MLX high in P 5.2 0.014606205 1.8 1025 249 76 97 823 755 365 N N N N N N RAD52 high in P 5.5 0.014633481 1.8 1026 13 6 7 14 18 36 N N N N N N DCTN2 high in P 4.0 0.0146403 1.8 1027 673 383 497 2806 2148 1227 N N N N N N CLDND2 high in P 7.1 0.014647119 1.8 1028 3 3 5 9 12 16 P P N N N N RHBDL1 high in P 4.2 0.014653938 1.8 1029 6 18 11 30 30 56 N N N N N N NMUR1 high in P 3.5 0.014667576 1.8 1030 15 15 22 45 73 61 N N N N N N TBC1D10C high in P 4.3 0.014704398 1.8 1031 6 7 7 15 15 56 P N N N N N LOC150381 high in P 3.7 0.014737811 1.8 1032 44 14 37 117 124 71 NA NA N N N N NT5DC3 high in P 5.7 0.014765087 1.8 1033 195 201 112 380 1578 965 N N N N P N TCIRG1 high in P 3.9 0.014794408 1.8 1034 251 117 226 1072 581 713 N N N N N N C11orf53 high in P 5.6 0.01480941 1.8 1035 4 12 16 64 49 34 N N N N N N ZC3H6 high in P 3.6 0.014816229 1.8 1036 161 166 362 775 874 718 N N N N N N CEP250 high in P 5.8 0.014823048 1.8 1037 50 24 27 143 64 107 N N N N N N OR52R1 high in P 4.0 0.014848278 1.8 1038 2 2 3 17 9 10 N P N N N N C12orf76 high in P 3.9 0.014855097 1.8 1039 25 16 8 49 29 54 NA NA N N N N C9orf23 high in P 3.1 0.014892601 1.8 1040 61 18 57 163 142 148 N N N N N N GINS1 high in P 6.0 0.014985339 1.8 1041 14 10 13 19 67 65 N N N N N N DYNLL1 high in P 5.0 0.014992158 1.8 1042 1669 758 1854 3758 5898 9528 N N N N N N ZDHHC19 high in P 4.7 0.015002387 1.8 1043 2 2 2 7 5 13 N N N N N N FAM186B high in P 4.7 0.015002387 1.8 1044 5 5 5 9 8 15 N N N N N N DZIP1L high in P 5.9 0.015028299 1.8 1045 24 12 41 56 119 99 N N N N N N MRPL48 high in P 6.2 0.015052847 1.8 1046 55 10 20 143 120 60 N N N N N N RABL2B high in P 5.7 0.015066485 1.8 1047 5 5 5 7 10 18 N N N N N N TROVE2 high in P 3.2 0.015073304 1.8 1048 172 165 245 633 631 748 N N N N N N YTHDC1 high in P 4.0 0.015112854 1.8 1049 814 477 850 2560 1926 3847 N N N N N N GALNT6 high in P 3.5 0.015119673 1.8 1050 24 31 28 74 91 43 P P N N N N PRPF4 high in P 3.3 0.015126492 1.8 1051 70 76 109 336 236 208 N N N N N N MRPS25 high in P 4.7 0.015167405 1.8 1052 124 81 93 292 476 1230 N N N N N N CHST2 high in P 3.8 0.015193317 1.8 1053 18 19 39 141 52 91 N N N N N N CRX high in P 4.4 0.015205592 1.8 1054 17 24 46 103 108 74 N P N N N N ACOT7 high in P 5.9 0.015226048 1.8 1055 346 52 255 721 1515 1434 N N N N N N MCF2L high in P 5.2 0.015232867 1.8 1056 50 24 25 198 95 92 N P N N N N DUS1L high in P 4.8 0.015273099 1.8 1057 134 80 226 715 897 367 N N N N N N ZNF709 high in P 2.9 0.015333788 1.8 1058 27 14 23 49 46 50 N N N N N N DHX34 high in P 3.6 0.015374702 1.8 1059 14 18 28 55 91 76 N N N N N N OGFOD2 high in P 4.7 0.015389021 1.8 1060 30 18 51 134 112 72 N N N N N N H2AFZ high in P 4.5 0.015416297 1.8 1061 1735 1197 3300 4751 8710 13578 N N N N P N FAM185A high in P 5.0 0.015436754 1.8 1062 4 4 4 8 22 15 NA NA N N N N MBLAC1 high in P 3.2 0.015462666 1.8 1063 14 8 12 23 25 23 NA NA N N N N ABCF1 high in P 3.7 0.01547835 1.8 1064 169 166 342 831 991 585 N N N N N N RIC8B high in P 3.7 0.015485169 1.8 1065 67 47 65 155 162 298 N N N N N N LOC284551 high in P 17.2 0.015500852 1.8 1066 2 15 2 21 27 23 NA NA N N N N WDR19 high in P 3.9 0.015523355 1.8 1067 9 48 32 118 80 97 N N N N N N SOX5 high in P 11.3 0.015538357 1.8 1068 36 9 10 52 29 160 N N N N N N ZNF296 high in P 5.6 0.015560859 1.8 1069 35 9 20 59 91 84 N N N N N N EIF3J high in P 4.6 0.015594954 1.8 1070 276 370 600 1013 2819 2233 N N N N N N GUF1 high in P 3.9 0.015616775 1.8 1071 26 29 12 94 95 56 N N N N N N CCR7 high in P 7.7 0.015623594 1.8 1072 6 33 23 166 47 645 N N N N N N WIPI1 high in P 3.8 0.01564405 1.8 1073 18 25 45 130 81 96 N N N N P N CREB3 high in P 3.7 0.015665871 1.8 1074 122 136 232 699 644 423 N N N N N N PPP2R5B high in P 4.5 0.015700648 1.8 1075 175 65 81 510 449 285 N N N N N N KIAA0355 high in P 2.9 0.015707467 1.8 1076 279 139 280 921 822 764 N N N N N N SAPS1 high in P 4.5 0.015721105 1.8 1077 321 192 629 1444 1529 1296 N N N N N N PPIL5 high in P 4.7 0.015736788 1.8 1078 8 13 11 53 55 19 N N N N N N CNTN4 high in P 8.6 0.015743607 1.8 1079 26 10 11 23 35 79 N N N N N N PIWIL4 high in P 4.6 0.015750426 1.8 1080 4 4 5 10 13 31 N N N N N N PPOX high in P 4.1 0.015770883 1.8 1081 4 5 5 12 20 20 N N N N N N PYCR1 high in P 7.0 0.015793386 1.8 1082 290 58 178 1175 1278 435 N N N N N N NEURL2 high in P 5.7 0.015807024 1.8 1083 35 6 8 43 44 130 N N N N N N RACGAP1 high in P 4.3 0.01584521 1.8 1084 31 38 41 78 104 225 N N N N N N ARFGAP1 high in P 4.7 0.015852029 1.8 1085 8 11 25 133 86 38 N N N N N N N4BP1 high in P 4.0 0.015858848 1.8 1086 57 38 42 196 187 110 N N N N N N UBE2G2 high in P 3.1 0.015865667 1.8 1087 237 363 509 1060 1302 1112 N N N N N N PAK1 high in P 3.9 0.015892942 1.8 1088 23 57 64 126 198 223 N N N N N N HSD17B10 high in P 4.2 0.015927037 1.8 1089 302 130 246 1261 1177 490 N N N N N N CEP57 high in P 4.1 0.015933856 1.8 1090 74 32 44 163 131 191 N N N N N P SNHG10 high in P 4.9 0.015940675 1.8 1091 6 20 18 59 31 79 N N N N N N CABLES1 high in P 7.3 0.015982271 1.8 1092 34 14 16 67 55 91 N N P N N N TRPM7 high in P 2.9 0.016023866 1.8 1093 65 89 93 210 187 286 N N N N N N BCAM high in P 22.3 0.016047733 1.8 1094 307 23 29 342 2658 522 N N N N N N FBXL6 high in P 4.0 0.016054552 1.8 1095 29 17 10 58 47 42 N N N N N N SLC26A6 high in P 6.8 0.016075009 1.8 1096 84 15 47 266 115 444 N N N N N N TRIM16 high in P 3.6 0.016081827 1.8 1097 536 264 839 1757 2228 1935 N N N N N N TMPRSS11B high in P 3.4 0.016088646 1.8 1098 23 25 23 66 43 91 N N N N N N REC8 high in P 5.3 0.016110467 1.8 1099 26 34 45 70 159 325 N N N N N P SPG7 high in P 3.7 0.016128196 1.8 1100 274 124 187 576 667 996 N N N N N N C12orf48 high in P 3.4 0.016135015 1.8 1101 3 4 11 24 32 19 N N N N N N DMRTA1 high in P 5.1 0.016150699 1.8 1102 14 2 3 10 10 23 N N N N N N KCTD17 high in P 4.7 0.016171156 1.8 1103 5 12 5 43 25 20 N N N N N N PLSCR2 high in P 3.3 0.016184794 1.8 1104 14 7 9 21 24 54 N N N N N N POMT2 high in P 3.5 0.016191613 1.8 1105 74 71 93 356 273 165 N N N N N N GSS high in P 4.7 0.016198432 1.8 1106 107 26 74 410 312 188 N N N N N N ANKS3 high in P 3.7 0.016220934 1.8 1107 31 33 63 131 145 87 N N N N N N ABCD4 high in P 2.7 0.016227753 1.8 1108 8 13 16 32 24 28 N N N N N N C17orf73 high in P 3.7 0.016307535 1.8 1109 55 33 74 153 178 163 NA NA N N N N HSF4 high in P 5.2 0.016326628 1.8 1110 18 9 19 26 56 139 N N N N N N CYP46A1 high in P 4.7 0.016347085 1.8 1111 3 3 4 6 8 14 N N N N N N ABHD8 high in P 9.6 0.016360723 1.8 1112 88 13 22 250 151 127 N N N N N N FPR3 high in P 5.8 0.016383225 1.8 1113 3 3 3 7 6 21 N P N N N N RPS6 high in P 5.7 0.016396863 1.8 1114 20377 9556 36974 127693 193466 64100 N N N N N N RIPK1 high in P 6.7 0.016403682 1.8 1115 237 64 60 704 544 400 N N N N N N C6orf129 high in P 9.1 0.01645687 1.8 1116 3 22 59 260 177 103 N N N N N N KLF8 high in P 3.4 0.016478691 1.8 1117 40 62 34 152 95 178 P N N N N N SLC23A2 high in P 5.9 0.01648551 1.8 1118 86 39 42 198 231 183 N N N N N N TBX2 high in P 23.4 0.016499148 1.8 1119 572 89 16 2600 690 1962 N N N N N N KIF9 high in P 4.2 0.016512786 1.8 1120 12 30 15 44 59 40 N N N N N N PPP4C high in P 3.2 0.016519605 1.8 1121 49 35 39 125 121 89 N N N N N N SNORA8 high in P 3.2 0.016531879 1.8 1122 17 6 12 24 29 28 N N N N N N ANXA5 high in P 3.1 0.016580293 1.8 1123 140 252 253 908 675 716 N N N N P N BFAR high in P 2.8 0.016593931 1.8 1124 40 23 34 94 71 93 N N N N N N C17orf68 high in P 2.7 0.016607569 1.8 1125 24 37 47 101 90 111 N N N N N N LOC388588 high in P 4.5 0.01665462 1.8 1126 14 3 6 18 16 32 N N N N N N INTU high in P 8.3 0.016681214 1.8 1127 19 9 12 16 43 74 N N N N N N ASAP2 high in P 3.4 0.016696897 1.8 1128 49 42 41 131 111 123 N N N N N N DTNBP1 high in P 3.8 0.016710535 1.8 1129 43 11 60 145 129 171 N N N N N N C14orf105 high in P 4.2 0.016723491 1.8 1130 5 5 5 15 13 8 N N N N N N MGC70857 high in P 4.9 0.016757586 1.8 1131 147 17 104 651 494 293 N N N N N N PATL1 high in P 3.6 0.016764405 1.8 1132 398 204 179 1233 603 1457 N N N N N N REEP1 high in P 4.6 0.016771224 1.8 1133 7 7 7 13 21 13 P P N N N N KIF1A high in P 10.1 0.01681282 1.8 1134 21 35 34 49 292 83 P N N N N N LOC286359 high in P 3.1 0.016823048 1.8 1135 14 15 12 39 22 34 NA NA N N N N STK11 high in P 3.1 0.016829867 1.8 1136 102 50 108 282 288 368 N N N N N P LRRC57 high in P 5.6 0.016862598 1.8 1137 23 7 11 52 43 71 N N N N N N PRPSAP2 high in P 6.1 0.016876236 1.8 1138 179 54 35 920 202 447 N N N P N N SHE high in P 5.9 0.016883055 1.8 1139 17 23 20 99 93 143 N N N N N N ZC3H3 high in P 3.5 0.016898738 1.8 1140 107 57 159 409 476 280 N N N N N N MIF4GD high in P 3.2 0.016930106 1.8 1141 36 37 18 75 62 93 N N N N N N PQLC1 high in P 4.2 0.016936925 1.8 1142 761 367 759 1578 2492 4201 N N N N N N LOC284232 high in P 3.3 0.016943744 1.8 1143 233 155 179 614 651 846 NA NA N N N N TCTEX1D4 high in P 5.3 0.016950563 1.8 1144 3 3 4 19 8 9 N N N N N N LLGL2 high in P 4.5 0.016957382 1.8 1145 14 21 49 79 200 77 N N N N N N CLPB high in P 5.1 0.016972383 1.8 1146 11 11 12 46 20 19 N N N N N N SCO1 high in P 3.9 0.016985339 1.8 1147 65 45 26 167 170 102 N N N N N N ZNF589 high in P 4.3 0.017013979 1.8 1148 33 13 27 64 39 106 N N N N N N VPS72 high in P 5.1 0.017041937 1.8 1149 191 46 156 770 772 324 N N N N N N DHX38 high in P 7.6 0.01705762 1.8 1150 234 68 44 828 304 1060 N N N N P N PLEKHF1 high in P 3.6 0.017069894 1.8 1151 181 99 153 337 668 484 N N N N N N POLR2I high in P 3.7 0.017096488 1.8 1152 51 54 69 220 234 98 N N N N N N RHBDD3 high in P 3.4 0.017112172 1.8 1153 64 29 43 132 127 113 N N N N P N NR5A2 high in P 4.4 0.017118991 1.8 1154 30 18 13 63 64 81 P P N N N N NUP214 high in P 3.5 0.017169451 1.8 1155 51 104 60 195 192 220 N N N N P N CCR6 high in P 3.8 0.017183089 1.8 1156 16 8 19 22 52 59 N P N N N N C19orf21 high in P 9.5 0.017218548 1.8 1157 6 11 16 39 132 26 N N N N N N SUV420H2 high in P 3.6 0.017246505 1.8 1158 23 25 33 77 70 277 N N N N N N PLCD4 high in P 4.4 0.017273781 1.8 1159 11 11 6 15 18 30 N N N N N N SCN4A high in P 7.1 0.0172806 1.8 1160 37 27 154 247 247 365 N N N N N N ZNF251 high in P 5.0 0.017324923 1.8 1161 17 21 6 56 40 53 N N N N N N AHNAK2 high in P 6.9 0.017341971 1.8 1162 46 22 24 49 112 259 N N N N N N PPARD high in P 4.1 0.017386976 1.8 1163 390 66 279 940 1655 1132 N N N N N N SLC10A7 high in P 9.1 0.017400614 1.8 1164 26 10 11 38 28 40 N N N N N N C8orf46 high in P 4.6 0.017407433 1.8 1165 27 12 8 40 40 36 N N N N N N ZXDC high in P 3.1 0.017421071 1.8 1166 188 115 163 736 474 473 N N N N N N SDHAP2 high in P 5.7 0.017487214 1.8 1167 14 17 46 91 61 216 NA NA N N N N IYD high in P 9.5 0.017494033 1.8 1168 29 8 10 56 31 67 N N N N N N RAPGEFL1 high in P 6.0 0.017533583 1.8 1169 44 13 24 189 115 56 N N N N N N ASAP3 high in P 8.4 0.017540402 1.8 1170 30 13 14 58 30 95 N N N N N N WHSC1 high in P 3.4 0.017576543 1.8 1171 70 88 59 279 314 270 N N N N N N PJA1 high in P 15.5 0.017590181 1.8 1172 158 14 21 336 265 282 N N N N N N ZNF7 high in P 5.1 0.017625639 1.8 1173 4 4 5 25 11 15 N N N N N N ILK high in P 3.9 0.017644732 1.8 1174 1034 222 660 2486 2454 2712 N N N N N N CCDC117 high in P 2.9 0.017660416 1.8 1175 58 80 56 224 137 221 N N N N N N GTF2B high in P 4.1 0.017679509 1.8 1176 120 123 253 489 468 588 N N N N N N CDK2AP2 high in P 5.7 0.017686328 1.8 1177 229 115 358 2279 616 841 N N N N N N CHCHD6 high in P 5.4 0.017711558 1.8 1178 79 16 40 195 183 106 N N N N N P DCPS high in P 6.7 0.017725196 1.8 1179 68 4 25 224 168 88 N N N N N N DFFA high in P 3.3 0.017747699 1.8 1180 29 32 41 110 167 60 N N N N N N LOC283174 high in P 5.5 0.017761337 1.8 1181 12 17 15 25 95 62 N N N N N N SULT2B1 high in P 7.4 0.017768155 1.8 1182 4 4 4 17 137 7 N P N N N N ACAP1 high in P 3.8 0.017781793 1.8 1183 12 17 24 55 48 286 P P N P N N ZNF625 high in P 4.9 0.017809751 1.7 1184 16 12 28 63 46 37 N N N N N N RNF216 high in P 2.9 0.01781657 1.7 1185 57 59 99 251 280 201 N N N P N N OSTC high in P 3.9 0.01784521 1.7 1186 5 5 5 11 12 13 NA NA N N N N KIAA0649 high in P 7.9 0.017888169 1.7 1187 53 15 15 85 85 60 N N N N N N DNAJB7 high in P 5.5 0.017894988 1.7 1188 5 5 7 22 23 10 N N N N N N RBM23 high in P 3.2 0.017908626 1.7 1189 255 87 204 825 566 526 N N N N N N SLC27A5 high in P 5.0 0.017969997 1.7 1190 43 11 41 111 178 75 N N N N N N DAK high in P 8.3 0.017976816 1.7 1191 150 28 38 287 410 213 N N N N N N KAT5 high in P 6.6 0.017983635 1.7 1192 58 53 12 376 145 112 N N N N N N L2HGDH high in P 2.9 0.017990453 1.7 1193 45 112 94 264 286 316 N N N N N N MRPS7 high in P 3.9 0.018002728 1.7 1194 196 85 132 614 621 316 N N N N N N ZNF814 high in P 3.9 0.018015002 1.7 1195 20 22 26 55 76 41 NA NA N N N N CCHCR1 high in P 3.7 0.018030685 1.7 1196 35 17 17 69 29 61 N N N N N N DRAM1 high in P 3.1 0.01806819 1.7 1197 69 104 91 281 185 310 NA NA N N N N LOC92659 high in P 3.2 0.018088646 1.7 1198 124 62 111 265 265 359 N N N N N N PDPK1 high in P 4.1 0.018182066 1.7 1199 106 64 58 269 225 326 N N N N P N ACADS high in P 3.7 0.018188885 1.7 1200 45 32 32 179 67 86 N N N N N N WWOX high in P 2.8 0.018233208 1.7 1201 18 17 21 51 33 31 N N N N N N CNPY3 high in P 4.3 0.018240027 1.7 1202 273 65 268 1144 893 537 N N N N N N ARPC3 high in P 4.7 0.018306853 1.7 1203 3 6 7 48 26 11 N N N N N N PRPSAP1 high in P 4.3 0.0183239 1.7 1204 82 30 37 104 367 376 N N N N N N PRR12 high in P 6.8 0.018395499 1.7 1205 99 29 40 343 166 201 N N N N N N NUFIP1 high in P 4.4 0.018402318 1.7 1206 20 26 37 165 102 50 N N N N N N STK32C high in P 3.8 0.018415956 1.7 1207 17 8 21 33 36 40 N N N N N N EPS8L1 high in P 5.2 0.01842823 1.7 1208 20 11 10 33 153 22 P N N N N N ADNP high in P 3.1 0.018448687 1.7 1209 58 106 129 305 246 391 N N N N N N ST6GALNAC4 high in P 6.0 0.018462325 1.7 1210 276 51 170 1730 755 448 N N N N N N DGKQ high in P 6.4 0.018487555 1.7 1211 51 13 22 87 125 75 N N N P N N BAT2L1 high in P 2.8 0.018494374 1.7 1212 1182 809 1508 3109 3508 3735 NA NA N N N N LMTK2 high in P 2.9 0.018514831 1.7 1213 138 178 206 520 613 631 N N N N N N USP40 high in P 5.3 0.01852165 1.7 1214 134 35 60 308 282 281 N N N N N N C3orf62 high in P 3.6 0.018528469 1.7 1215 44 25 36 97 106 144 N N N N N N ABCF3 high in P 3.1 0.018535288 1.7 1216 68 73 116 201 240 214 N N N N N N PANX2 high in P 2.8 0.0185612 1.7 1217 12 28 41 103 71 80 N N N N N N SHISA4 high in P 6.5 0.018585748 1.7 1218 77 15 22 152 92 134 N N N N N N TBKBP1 high in P 3.2 0.018626662 1.7 1219 20 15 22 42 44 37 N N N N N N FZR1 high in P 2.7 0.018633481 1.7 1220 58 45 62 148 163 173 N N N N N N DUS3L high in P 5.3 0.018667576 1.7 1221 99 57 228 600 897 293 N N N N N N OBSCN high in P 5.2 0.018674395 1.7 1222 108 79 126 193 436 535 N N P N N N CLEC17A high in P 4.5 0.018693488 1.7 1223 4 8 4 14 11 24 N N N N N N OGDH high in P 4.9 0.018700307 1.7 1224 319 107 176 977 854 515 N N N N N N C2orf68 high in P 2.9 0.018741902 1.7 1225 111 91 48 364 265 256 N N N N N N RPS10 high in P 6.8 0.018769178 1.7 1226 9 9 9 23 30 21 N N N N N N CTDP1 high in P 3.0 0.018789635 1.7 1227 91 49 75 199 245 151 N N N N N P KIF21B high in P 10.0 0.018813502 1.7 1228 48 16 18 45 111 142 N N N N N N GRM2 high in P 4.9 0.018841459 1.7 1229 2 2 2 13 4 24 N N N N N N CLDN4 high in P 10.6 0.018855097 1.7 1230 157 59 32 462 401 263 N N N N N N TMEM86B high in P 4.9 0.018926014 1.7 1231 7 11 8 38 17 71 N N N N N N CENPT high in P 3.8 0.018945107 1.7 1232 106 131 249 425 596 424 N N N N N N ATR high in P 3.8 0.018977838 1.7 1233 36 25 39 108 113 54 N N N N N N CENPM high in P 4.1 0.018984657 1.7 1234 2 5 6 12 27 13 N N N N N N CCDC41 high in P 2.7 0.018991476 1.7 1235 6 12 12 27 47 23 N N N N N N XRCC2 high in P 3.6 0.019009206 1.7 1236 674 476 971 2481 1625 2383 N N N N N N AFMID high in P 2.7 0.019049437 1.7 1237 9 22 18 38 44 72 N N N N N N PAK6 high in P 9.5 0.019078759 1.7 1238 9 14 14 42 158 19 N N N N N N PTCD3 high in P 3.1 0.019149676 1.7 1239 74 91 100 201 405 281 N N N N N N METTL11A high in P 3.2 0.019156495 1.7 1240 263 190 111 620 547 515 N N N N N N PDCD11 high in P 3.1 0.019166723 1.7 1241 56 97 66 177 253 171 N N N N N N HAUS5 high in P 4.4 0.019202864 1.7 1242 71 24 45 162 183 174 NA NA N N N N TMC8 high in P 5.8 0.019223321 1.7 1243 17 5 11 14 42 134 N N N N N N TUBGCP5 high in P 5.5 0.019251279 1.7 1244 43 21 27 120 62 111 N N N N P N SLC29A1 high in P 4.3 0.019285373 1.7 1245 645 183 394 1556 1980 1082 N N N N N N SEC16A high in P 3.5 0.019292192 1.7 1246 220 162 378 840 1045 645 N N N N N N GATS high in P 21.9 0.019314695 1.7 1247 88 9 12 235 74 174 N N N N N N LYPD3 high in P 4.2 0.019321514 1.7 1248 47 59 84 152 711 182 N N N N N N PLOD3 high in P 3.9 0.019350835 1.7 1249 275 121 178 667 731 464 N N N P N N APOO high in P 5.7 0.019394477 1.7 1250 2 9 2 23 12 15 N N N N N N DHRS12 high in P 4.2 0.019414934 1.7 1251 43 12 23 84 63 140 N N N N N N TFRC high in P 3.0 0.019441527 1.7 1252 188 265 276 528 1069 743 N N N N N N NINL high in P 3.2 0.019448346 1.7 1253 8 9 9 16 13 21 NA NA N N N N FAM48A high in P 3.0 0.019480395 1.7 1254 9 37 34 105 73 68 N N N N N N TNIK high in P 3.1 0.019500852 1.7 1255 15 17 24 26 38 42 N N N N P N TTC38 high in P 2.6 0.019507671 1.7 1256 29 26 21 83 61 58 N N N N N N CHST5 high in P 8.2 0.019521309 1.7 1257 23 6 7 31 42 22 N N N N N N HIVEP3 high in P 6.2 0.019540402 1.7 1258 124 108 129 237 690 954 N N N N P N ZSWIM7 high in P 3.1 0.019555404 1.7 1259 12 9 18 49 53 33 N N N N N N RNF112 high in P 7.1 0.019562223 1.7 1260 23 6 8 43 18 79 N N N N N N DYRK1B high in P 2.4 0.019602455 1.7 1261 36 46 44 77 85 82 N N N N N N ITCH high in P 2.7 0.019614729 1.7 1262 35 48 41 150 103 84 N N N N N N GCDH high in P 3.5 0.019634504 1.7 1263 65 35 44 201 149 110 N N N N N N EIF2B5 high in P 4.4 0.019653597 1.7 1264 99 108 309 594 833 414 N N N N N N FASN high in P 2.7 0.019660416 1.7 1265 89 127 183 355 477 433 N N N N N N SNAPC4 high in P 3.6 0.019667235 1.7 1266 23 32 58 95 148 88 N N N N N N C16orf46 high in P 2.9 0.019680191 1.7 1267 4 6 5 14 11 10 N N N N N N RUFY1 high in P 3.9 0.019707467 1.7 1268 105 43 60 250 202 179 N N N N N N EIF4G1 high in P 3.2 0.019714286 1.7 1269 196 139 237 645 783 423 N N N N N N ZNF544 high in P 3.3 0.019741562 1.7 1270 22 21 32 89 113 50 N N N N N N SMG6 high in P 4.8 0.019757245 1.7 1271 327 53 157 674 655 863 N N P N N P HES6 high in P 4.5 0.019769519 1.7 1272 69 13 29 170 101 121 N N N N N N FAM70B high in P 5.7 0.019785203 1.7 1273 27 1 4 52 33 24 P N N N N N GALNTL2 high in P 2.5 0.019800886 1.7 1274 24 64 58 149 157 151 N N N N N N ZNF792 high in P 10.8 0.01981657 1.7 1275 21 5 5 26 16 15 N N N N N N CCDC154 high in P 4.5 0.019835663 1.7 1276 2 9 14 39 20 37 NA NA N N N N RAB4A high in P 3.2 0.01985612 1.7 1277 119 109 82 209 395 332 N N N N N N SV2A high in P 4.5 0.019871804 1.7 1278 64 48 32 495 179 82 N N N N N N SUV420H1 high in P 3.0 0.019913399 1.7 1279 30 33 25 54 75 100 N N N N N N PLCD3 high in P 2.8 0.019925673 1.7 1280 434 334 465 952 988 1233 N N N N N N ATG4B high in P 3.0 0.019932492 1.7 1281 238 120 259 674 584 764 N N N N N N TMEM43 high in P 3.4 0.019939311 1.7 1282 385 209 316 1056 1470 766 N N N N N N PDIA3 high in P 3.4 0.019982271 1.7 1283 49 28 38 142 73 82 N N N N N N SMC1A high in P 3.1 0.019995909 1.7 1284 63 93 82 291 241 155 N N N N N N RPS17 high in P 2.6 0.020002728 1.7 1285 7393 6281 7884 19271 16888 16116 N N N N N N SRP72 high in P 5.3 0.020030003 1.7 1286 259 176 82 1331 474 513 N N N N N N CHDH high in P 2.4 0.020036822 1.7 1287 33 28 37 69 72 59 N N N N N N FRY high in P 3.3 0.02005046 1.7 1288 49 37 23 96 88 69 N N N N N N LRG1 high in P 9.9 0.020111831 1.7 1289 51 8 49 51 466 453 N N N N N N HSF1 high in P 3.7 0.02011865 1.7 1290 461 337 787 1559 2711 1261 N N N N N N ADPRHL1 high in P 6.8 0.020125469 1.7 1291 7 7 8 27 19 30 N N N N N N SLC25A26 high in P 3.0 0.020141152 1.7 1292 196 130 108 328 502 412 N N N N N N C21orf2 high in P 5.8 0.020165019 1.7 1293 282 26 118 890 760 502 N N N N N N SLC24A2 high in P 4.0 0.020178657 1.7 1294 2 2 2 8 5 5 N P N N N N COX10 high in P 2.8 0.020185476 1.7 1295 11 16 13 30 37 24 N N N N P N ITK high in P 5.7 0.020192295 1.7 1296 15 10 5 14 29 152 P N N N N N GDH high in P 9.0 0.020207978 1.7 1297 260 40 61 547 406 516 N N N N N N SNORD100 high in P 3.9 0.020243437 1.7 1298 9 15 22 32 81 48 N N N N N N ADAMTS2 high in P 2.7 0.020265939 1.7 1299 23 30 27 68 62 53 N N N N N N TOM1 high in P 6.0 0.020324582 1.7 1300 189 176 53 1261 398 481 N N N N N N FMNL3 high in P 4.5 0.020331401 1.7 1301 259 100 96 790 432 1332 N N N N N N DPP9 high in P 4.3 0.020396863 1.7 1302 293 125 280 1486 1002 488 N N N N N N MRPL4 high in P 2.9 0.020422093 1.7 1303 33 96 97 258 290 273 N N N N N N IL1B high in P 8.2 0.020441186 1.7 1304 97 43 38 323 96 920 N P N N N N SULT1B1 high in P 2.7 0.020448005 1.7 1305 1 1 1 3 4 6 N N N N N N ODF3B high in P 3.7 0.0204821 1.7 1306 100 77 179 287 408 337 N N N N N N GGNBP2 high in P 3.3 0.020517559 1.7 1307 214 179 350 651 796 1079 N N N P N N PLAU high in P 5.9 0.02066553 1.7 1308 1131 323 467 6871 3924 1175 N N N N N N ARHGAP27 high in P 4.1 0.020707126 1.7 1309 46 20 90 172 238 140 N N N N N N SUSD5 high in P 2.7 0.020713945 1.7 1310 20 24 23 62 48 40 N N N N N N SPHAR high in P 4.4 0.020739857 1.7 1311 14 5 2 16 19 8 N N N N N N TEX264 high in P 3.7 0.020795772 1.7 1312 297 62 184 862 542 620 N N N N N N PPFIA4 high in P 3.6 0.02080941 1.7 1313 26 10 10 52 20 31 N N N N N N GPT2 high in P 4.9 0.020838732 1.7 1314 42 18 21 72 320 49 N N N N N N HYAL3 high in P 3.3 0.020859189 1.7 1315 4 4 5 10 18 10 N N N N N N TMEM81 high in P 5.6 0.020885101 1.7 1316 2 3 4 7 14 41 N N N N N N CLIC6 high in P 3.9 0.020939652 1.7 1317 8 8 8 10 13 11 P P N N N N POLB high in P 3.9 0.020939652 1.7 1318 6 6 6 8 11 9 N N N N N N ZNF414 high in P 3.4 0.020979202 1.7 1319 6 16 12 76 31 19 N N N N N N KDM6B high in P 4.1 0.020986021 1.7 1320 3244 2398 4696 8013 13700 27971 NA NA N N N N CDH13 high in P 2.9 0.020998295 1.7 1321 43 36 29 63 88 80 P P N N N N MPP6 high in P 3.3 0.021013297 1.7 1322 27 14 12 27 55 54 N N N N N N TSC1 high in P 2.7 0.021020116 1.7 1323 32 52 50 100 92 132 N N N N N N APOBEC3H high in P 3.9 0.021026935 1.7 1324 2 2 3 5 8 16 N N N N N N SLC5A5 high in P 3.9 0.021045346 1.7 1325 34 60 78 154 137 289 N P N N N N FGFR3 high in P 4.9 0.021101943 1.7 1326 41 24 39 58 151 458 N N N N N N NIPAL1 high in P 3.1 0.021114899 1.7 1327 17 7 15 25 24 36 NA NA N N N N AAAS high in P 3.1 0.021121718 1.7 1328 63 39 43 192 123 91 N N N N N N CUL9 high in P 4.0 0.021135356 1.7 1329 75 25 51 126 147 253 NA NA N N N N GPAT2 high in P 5.3 0.021155813 1.7 1330 41 10 18 211 88 35 NA NA N N N N KDM1B high in P 3.6 0.021189908 1.7 1331 7 7 8 11 10 15 NA NA N N N N PIGP high in P 3.7 0.021224003 1.7 1332 78 27 29 155 86 118 N N N N P N HPX high in P 4.8 0.02124446 1.7 1333 9 12 19 31 22 39 N N N N N N PRRT1 high in P 8.5 0.021285373 1.7 1334 52 6 10 63 72 115 N N N N N N ATG2B high in P 3.1 0.021304466 1.7 1335 41 52 52 134 79 124 N N N N N N CCDC149 high in P 3.2 0.021311285 1.7 1336 15 20 25 42 43 79 N N N N N N CST7 high in P 6.0 0.021318104 1.7 1337 82 94 25 242 142 548 N N N N N N SAPS2 high in P 2.3 0.02133106 1.7 1338 38 49 54 109 93 101 N N N N N N TRAF6 high in P 2.5 0.021351517 1.7 1339 9 13 14 25 21 32 N N N N N N ARGFX high in P 5.3 0.021376065 1.7 1340 14 16 17 55 41 39 N N N N N N C21orf94 high in P 3.7 0.021391749 1.7 1341 3 6 3 7 17 11 NA NA N N N N FIP1L1 high in P 3.3 0.021398568 1.7 1342 16 10 27 40 79 54 N N N N N N ANKRD13B high in P 3.4 0.021415615 1.7 1343 60 75 82 137 269 242 N N N N N N CTRC high in P 8.4 0.021455847 1.7 1344 29 3 6 26 66 49 N N N N N N STK39 high in P 4.6 0.021470167 1.7 1345 135 13 62 284 509 249 N N N N P N TATDN3 high in P 3.5 0.021489942 1.7 1346 9 20 31 94 62 42 N N N N N N CTSS high in P 2.8 0.021526083 1.7 1347 23 27 17 63 54 40 N N N N N N MARS high in P 5.2 0.021532901 1.7 1348 579 490 370 3447 2426 858 N N N N N N AARSD1 high in P 2.7 0.021560177 1.7 1349 22 34 35 70 51 77 N N N N N N ZFPM1 high in P 3.9 0.021570406 1.7 1350 59 23 30 121 182 74 N N N N N N RIMS1 high in P 4.2 0.021584044 1.7 1351 13 13 14 23 19 16 N N N N N N MRPS15 high in P 3.0 0.021597682 1.7 1352 84 47 38 215 183 93 N N N N N N LOC100271831 high in P 5.7 0.021604501 1.7 1353 7 2 9 48 12 14 NA NA N N N N POLR3D high in P 2.5 0.021616775 1.7 1354 18 17 18 34 32 48 N N N N N N ABCF2 high in P 2.3 0.021634504 1.7 1355 625 504 713 1590 1536 1440 N N N N N P TRIM11 high in P 2.2 0.021668599 1.7 1356 91 82 76 193 170 189 N N N N N N NICN1 high in P 5.3 0.021686328 1.7 1357 34 15 22 65 79 104 N N N N N N SFXN2 high in P 2.4 0.021702012 1.7 1358 12 9 10 20 17 21 N N N N N N NUDT22 high in P 4.8 0.02174088 1.7 1359 16 20 12 132 62 23 N N N N N N TSSC1 high in P 4.9 0.021769519 1.7 1360 16 8 6 53 40 13 N N N N P N C19orf6 high in P 3.4 0.021804296 1.7 1361 924 306 1515 3355 3483 2937 N N N N N N CARD10 high in P 7.3 0.021842482 1.7 1362 79 24 31 116 574 99 N N N N N N ZNF737 high in P 3.2 0.021923628 1.7 1363 41 28 43 90 120 140 NA NA N N N N RBM5 high in P 3.5 0.021956359 1.7 1364 104 196 398 689 640 1281 N N N N N N TNFRSF9 high in P 3.6 0.02197136 1.7 1365 10 15 7 38 23 60 P P N N N N NFIC high in P 5.6 0.022038186 1.7 1366 830 183 238 2526 1203 1265 N N N N N N HSPA1L high in P 6.0 0.022113877 1.7 1367 4 6 14 28 15 186 N N N N N N BAIAP2L1 high in P 5.3 0.022134333 1.7 1368 159 70 136 376 2406 400 N N N N N N DKFZp686O24166 high in P 2.9 0.022214115 1.7 1369 12 17 14 29 22 31 NA NA N N N N RPS6KL1 high in P 3.7 0.022220934 1.7 1370 17 13 16 53 53 21 N N N N N N TRPV4 high in P 5.8 0.022259802 1.7 1371 10 4 4 14 29 7 N N N N N N SIRT7 high in P 3.7 0.02227344 1.7 1372 31 71 53 105 180 170 N N N N P N RHEBL1 high in P 5.4 0.022315036 1.7 1373 10 29 6 34 41 72 N N N N N N CLEC4E high in P 4.1 0.022332083 1.7 1374 4 12 14 49 20 208 N N N N N N SPRYD4 high in P 6.0 0.022338902 1.7 1375 59 15 16 107 81 78 N N N N N N BMS1P1 high in P 4.0 0.022364814 1.7 1376 2 5 9 20 15 34 NA NA N N N N MPND high in P 2.5 0.02239209 1.6 1377 30 15 25 49 53 42 N N N N N N PATE4 high in P 5.3 0.022413229 1.6 1378 5 27 9 46 50 39 NA NA N N N N ANKRD9 high in P 2.8 0.022420048 1.6 1379 163 67 113 365 304 298 N N N N N N XRCC3 high in P 3.3 0.022435049 1.6 1380 6 7 10 27 25 14 N N N N N N RNF125 high in P 5.3 0.02245687 1.6 1381 33 18 15 70 58 75 N N N N N N C4orf14 high in P 4.6 0.022479373 1.6 1382 193 32 74 303 473 311 N N N N N N UNC50 high in P 2.7 0.022501875 1.6 1383 105 70 61 233 174 161 N N N N N N SLMAP high in P 4.1 0.022508694 1.6 1384 30 49 90 192 177 138 N N N N N N DPP7 high in P 2.6 0.022531197 1.6 1385 176 96 201 443 454 435 N N N N N N B3GALT4 high in P 3.3 0.022541425 1.6 1386 3 11 13 29 34 28 N N N N N N SDF4 high in P 4.4 0.022555745 1.6 1387 1254 406 650 3664 2755 1754 N N N N N N LRRC56 high in P 6.8 0.022576202 1.6 1388 24 9 9 35 35 108 N N N N N N CXCL17 high in P 7.0 0.022588476 1.6 1389 3 15 13 55 113 21 N N N N N N TMEM149 high in P 5.4 0.022595295 1.6 1390 29 2 9 51 31 50 N N N N N N FAM55C high in P 6.7 0.022635527 1.6 1391 149 50 38 234 271 365 N N N N N N HSPB1 high in P 9.8 0.022703034 1.6 1392 105 23 376 390 630 3417 N N N N N N C5AR1 high in P 3.6 0.022725537 1.6 1393 13 9 8 22 14 36 N N N N N N NAIP high in P 3.0 0.022732356 1.6 1394 30 35 50 82 71 156 N N N N N N MUC2 high in P 2.7 0.022754859 1.6 1395 3 3 3 6 6 11 N N N N N N NAPSA high in P 2.7 0.022754859 1.6 1396 1 1 1 3 4 9 N N N N N N AATF high in P 2.9 0.022862598 1.6 1397 28 92 76 224 208 171 P P N N N N MAP3K4 high in P 2.6 0.022883055 1.6 1398 31 86 83 202 163 193 N N N N N N CNTD2 high in P 7.1 0.022953972 1.6 1399 66 10 34 62 210 546 P N N N N N UBE3B high in P 2.8 0.022988749 1.6 1400 21 29 24 81 50 63 N N N N N N CACNA2D3 high in P 3.9 0.023010569 1.6 1401 14 8 8 10 17 16 N P N N N N RASA4P high in P 4.4 0.023039891 1.6 1402 128 36 72 254 183 540 N N N N N N RFPL1S high in P 3.7 0.023081487 1.6 1403 44 15 21 64 77 46 N N N N N N WDR44 high in P 2.8 0.023134674 1.6 1404 61 43 59 117 129 237 N N N N N N CLDN15 high in P 3.3 0.023207637 1.6 1405 9 21 22 44 55 54 N N N N N N PPAPDC2 high in P 8.7 0.023221275 1.6 1406 24 12 12 59 47 29 N N N N N N MYST3 high in P 3.0 0.023236959 1.6 1407 519 241 500 1164 1396 1829 N N N N N N XPO4 high in P 2.5 0.023257416 1.6 1408 20 38 30 80 90 54 N N N N N N PIGS high in P 4.3 0.02326969 1.6 1409 192 68 81 578 319 296 N N N N N N LOC646851 high in P 4.7 0.023296966 1.6 1410 133 62 66 249 317 262 NA NA N N N N ZFP28 high in P 2.9 0.023303785 1.6 1411 19 12 10 27 17 27 N N N N N N BID high in P 2.6 0.023310603 1.6 1412 79 143 158 309 409 355 N N N N N N ZNF121 high in P 2.6 0.023378111 1.6 1413 7 11 11 32 30 18 N P N N N N ZFYVE26 high in P 4.0 0.023400614 1.6 1414 17 20 19 59 36 48 N N N N N N CLPTM1 high in P 2.3 0.023407433 1.6 1415 339 373 402 902 854 726 N N N N N N HEATR2 high in P 7.3 0.023434027 1.6 1416 26 12 9 36 50 50 N N N N N N SOCS7 high in P 3.3 0.023585407 1.6 1417 9 3 4 7 15 11 N N N N N N MOSPD3 high in P 4.0 0.023599045 1.6 1418 25 6 20 87 56 25 N N N N P N MT1L high in P 6.2 0.023624957 1.6 1419 14 44 47 71 130 278 N N N N N N MARK4 high in P 3.2 0.023663144 1.6 1420 176 115 130 355 658 342 N N N N N N C17orf77 high in P 4.2 0.023691101 1.6 1421 5 5 5 9 10 16 P P N N N N CDKN2BAS high in P 3.9 0.023704739 1.6 1422 7 8 7 9 12 18 NA NA N N N N PURA high in P 2.7 0.023730651 1.6 1423 28 31 31 85 72 50 N N N N N N ZNF143 high in P 2.5 0.02379134 1.6 1424 27 49 45 80 99 84 N N N N N N KIAA1530 high in P 3.0 0.023818616 1.6 1425 56 36 52 111 127 136 N N N N N N C13orf34 high in P 3.2 0.023825435 1.6 1426 5 8 14 35 18 32 N N N N N N THUMPD3 high in P 5.0 0.023890215 1.6 1427 10 12 10 30 40 13 N N N N N N SF3B4 high in P 3.2 0.02393522 1.6 1428 584 477 335 1990 1275 1085 N N N N N N OTX2OS1 high in P 2.6 0.023992499 1.6 1429 6 7 10 23 20 28 NA NA N N N N NLRX1 high in P 8.1 0.024032049 1.6 1430 41 9 11 64 40 34 N N N N N N CNTFR high in P 6.2 0.024053188 1.6 1431 100 14 30 162 110 230 N N N N P N PARN high in P 3.2 0.024066826 1.6 1432 98 77 79 386 212 145 N N N N N N FGF17 high in P 3.8 0.024096147 1.6 1433 3 8 10 13 19 33 P P N N N N GJB2 high in P 3.7 0.024111831 1.6 1434 3 8 8 29 47 14 N P N N N N ZNF516 high in P 3.3 0.024181384 1.6 1435 48 45 72 237 103 262 N N N N N N IFI30 high in P 4.6 0.024210024 1.6 1436 32 85 52 120 150 467 N N N N N N DUS2L high in P 5.5 0.024261848 1.6 1437 3 10 7 45 48 11 N N N N N N PIH1D1 high in P 2.6 0.024282987 1.6 1438 155 158 138 854 314 370 N N N N N N PPAN high in P 3.4 0.024303444 1.6 1439 107 47 92 173 328 213 N N N N N N KIAA1875 high in P 2.6 0.024369587 1.6 1440 959 531 1294 2535 2665 2467 N N N N N N LRRC4B high in P 6.1 0.024376406 1.6 1441 43 8 19 168 33 93 N N N N N N RNASEH1 high in P 4.5 0.02442073 1.6 1442 84 26 29 294 110 92 N N N N N N ARRB2 high in P 3.1 0.024441868 1.6 1443 18 17 11 42 28 59 N N N N N N IRX1 high in P 3.7 0.024484828 1.6 1444 71 96 132 307 1693 202 N P P N N N DLG4 high in P 2.8 0.024498466 1.6 1445 16 30 39 77 51 87 N N N N N N TMEM63B high in P 3.3 0.024571429 1.6 1446 106 102 253 332 564 530 N N N N N N KCNE1L high in P 5.3 0.024598704 1.6 1447 2 2 3 5 16 18 N P N N N N INTS9 high in P 3.2 0.024643028 1.6 1448 46 24 33 66 94 53 N N N N N N TRIM38 high in P 2.6 0.024662121 1.6 1449 16 29 24 43 48 66 N N N N N N NME4 high in P 3.3 0.024675759 1.6 1450 128 84 170 450 363 260 N N N N P N HADHA high in P 3.6 0.024682578 1.6 1451 793 351 438 1739 1722 1233 N N N N N N POLL high in P 5.2 0.024689397 1.6 1452 69 10 28 137 109 116 N N N N N N RPS6KA5 high in P 3.2 0.024696215 1.6 1453 34 47 28 57 74 95 N N N N N N ORC6L high in P 3.1 0.024709853 1.6 1454 50 37 48 142 66 126 N N N N N N SLC9A5 high in P 3.1 0.024726901 1.6 1455 21 17 13 33 38 32 N N N N N N C17orf55 high in P 5.3 0.024757586 1.6 1456 6 7 11 49 12 81 N N N N N N AGGF1 high in P 3.2 0.02477327 1.6 1457 14 13 10 43 29 31 P N N N N N LIG4 high in P 5.2 0.024816911 1.6 1458 13 38 30 149 103 41 N N N N N N MURC high in P 3.5 0.024890556 1.6 1459 7 10 11 21 21 72 N N N N N N MEFV high in P 4.0 0.024897375 1.6 1460 5 5 6 9 8 18 N P N N N N STAT4 high in P 8.7 0.024904194 1.6 1461 66 8 9 82 54 270 N N N N N N NTN5 high in P 3.8 0.024911013 1.6 1462 5 5 7 13 10 22 NA NA N N N N ZNF134 high in P 3.0 0.024924651 1.6 1463 7 11 8 23 12 18 N N N N N N GLO1 high in P 3.6 0.024938288 1.6 1464 1633 586 842 5786 4437 1892 N N N N N N SYNRG high in P 3.1 0.024945107 1.6 1465 33 39 61 88 110 202 NA NA N N N N LOC55908 high in P 4.0 0.024972383 1.6 1466 3 3 4 7 6 14 N N N N N N TARBP2 high in P 3.2 0.025011251 1.6 1467 24 37 29 106 53 52 N N N N N N ADCY2 high in P 4.5 0.025031708 1.6 1468 46 21 45 77 93 196 N N N N N N SMYD4 high in P 5.8 0.025054211 1.6 1469 142 24 41 203 199 286 N N N N N N MTPAP high in P 3.2 0.025067849 1.6 1470 571 493 996 1851 2042 1905 NA NA N N N N ZC3H8 high in P 3.6 0.025087624 1.6 1471 4 14 5 20 32 20 N N N N N N SLC35C2 high in P 4.1 0.025114899 1.6 1472 123 58 100 730 252 202 N N N N N N TCAM1 high in P 4.0 0.025121718 1.6 1473 NA NA NA NA NA NA N N N N N N DONSON high in P 3.0 0.025128537 1.6 1474 12 11 9 17 34 23 N N N N N N DLGAP3 high in P 3.2 0.02515104 1.6 1475 4 4 5 17 9 10 P P N P N N HSCB high in P 2.6 0.025164678 1.6 1476 51 59 81 158 142 211 N N N N N N ADRA2C high in P 4.0 0.025185135 1.6 1477 97 84 85 2125 321 182 N P N N N N ACY1 high in P 3.3 0.025207637 1.6 1478 118 40 88 240 355 168 N N N N N N RBAK high in P 3.0 0.025233549 1.6 1479 15 25 29 56 40 104 N N N N N N BAT3 high in P 3.6 0.025240368 1.6 1480 1574 652 814 4512 3260 2233 N N N N N N FLJ13197 high in P 4.4 0.025256052 1.6 1481 6 6 6 11 13 22 NA NA N N N N SRRM3 high in P 5.0 0.025326969 1.6 1482 6 7 17 21 19 42 NA NA N N N N ZMIZ2 high in P 3.4 0.025425844 1.6 1483 201 86 310 576 820 720 N N P N N N FLJ25363 high in P 3.1 0.025466758 1.6 1484 9 17 9 25 23 30 NA NA N N N N ATMIN high in P 3.3 0.025484487 1.6 1485 102 45 72 306 227 188 N N N N N N ALPK3 high in P 2.7 0.02550358 1.6 1486 20 24 37 83 52 54 N N N N N N OTUD4 high in P 3.4 0.025510399 1.6 1487 970 765 790 1647 3026 3983 N N N N N N NBEAL2 high in P 3.9 0.025551313 1.6 1488 77 51 108 146 297 383 N N N N N N ELP2P high in P 3.9 0.025619502 1.6 1489 6 6 6 8 14 24 N N N N N N RP1-177G6.2 high in P 2.9 0.025635186 1.6 1490 27 18 25 57 32 69 N P N N N N LOC642587 high in P 4.8 0.025645414 1.6 1491 307 126 98 525 3189 432 N N N N N N ZBTB32 high in P 8.6 0.025657688 1.6 1492 2 2 3 5 14 30 N N N N N N SERPINC1 high in P 2.9 0.025691783 1.6 1493 3 11 4 15 15 24 N N N N N N RAI1 high in P 3.0 0.025698602 1.6 1494 305 195 258 519 782 973 N N P N N N TAF1D high in P 2.6 0.025733379 1.6 1495 311 270 392 708 730 951 N N N N N N SLC12A3 high in P 2.8 0.02579134 1.6 1496 5 6 7 13 16 10 N N N N N N FLJ45445 high in P 5.3 0.025806342 1.6 1497 243 106 6 545 497 495 NA NA N N N N MCRS1 high in P 3.2 0.02581998 1.6 1498 61 41 33 208 105 78 N N N N N N TRIM68 high in P 4.5 0.025897034 1.6 1499 12 6 6 22 11 26 N N N N N N LSG1 high in P 3.9 0.025903853 1.6 1500 28 13 17 42 48 68 N N N N N N ATP5S high in P 4.8 0.025910672 1.6 1501 6 8 14 20 18 22 N N N N N N LOC400043 high in P 5.4 0.025942039 1.6 1502 370 98 111 608 545 681 NA NA N N N N UBXN11 high in P 3.1 0.025976816 1.6 1503 33 27 53 63 115 100 N N N N N N CCDC17 high in P 3.8 0.025983635 1.6 1504 12 7 8 21 19 52 N N N N N N MYH14 high in P 3.4 0.026035459 1.6 1505 21 29 40 68 415 63 N P N N N N C11orf92 high in P 4.0 0.026184112 1.6 1506 10 10 10 13 13 35 NA NA N N N N STX4 high in P 3.1 0.026263212 1.6 1507 541 460 915 1650 1365 2331 N N N N N N CLDN14 high in P 2.6 0.026270031 1.6 1508 4 12 7 14 23 17 P P N N N N FAM189B high in P 3.4 0.026288442 1.6 1509 73 55 142 299 228 196 NA NA N N N N SERTAD3 high in P 2.9 0.026308899 1.6 1510 33 16 29 45 63 78 N N N N N P RAD1 high in P 2.6 0.026345721 1.6 1511 40 38 25 92 123 89 N N N N N N PCNT high in P 3.0 0.026435049 1.6 1512 95 39 151 348 277 411 N N N N N N CASP9 high in P 3.3 0.026441868 1.6 1513 84 11 62 157 181 254 N N N N N N ADSSL1 high in P 5.6 0.026570065 1.6 1514 40 9 6 32 45 177 N N N N N N KIAA1949 high in P 7.6 0.026576884 1.6 1515 6446 953 888 7209 7145 18747 N N N N N N MAPKSP1 high in P 2.8 0.02662939 1.6 1516 72 191 176 374 522 413 N N N N N N ATP2A1 high in P 5.4 0.026656666 1.6 1517 5 9 5 26 10 13 N N N N N N WDR4 high in P 3.5 0.026670303 1.6 1518 40 31 25 54 120 143 N N N N N N TEAD4 high in P 2.8 0.026756222 1.6 1519 124 144 204 281 536 473 N N N N N N FAM116B high in P 3.2 0.026763041 1.6 1520 34 12 23 44 77 40 N N N N N N DHX37 high in P 3.2 0.026857143 1.6 1521 39 64 117 204 361 160 N N N N N N LOC348926 high in P 4.2 0.026863962 1.6 1522 6 6 6 22 11 9 N N N N N N RNF215 high in P 3.2 0.02691715 1.6 1523 55 11 25 116 69 65 N N N N N N FGR high in P 4.6 0.026939652 1.6 1524 18 6 18 36 20 68 N N N N N N CD300C high in P 4.2 0.026975793 1.6 1525 2 2 5 14 8 30 P N N N N N RRAGD high in P 2.9 0.027003069 1.6 1526 49 84 43 191 180 97 N N N N N N MCCC2 high in P 3.7 0.027058984 1.6 1527 183 72 90 420 406 233 N N N N N N LOC401093 high in P 2.8 0.027079441 1.6 1528 49 36 34 67 81 94 NA NA N N N N MED19 high in P 2.9 0.027118309 1.6 1529 220 181 87 672 401 535 N N N N N N CCDC22 high in P 3.4 0.027184453 1.6 1530 55 22 30 156 83 74 N N N N N N ZNF323 high in P 3.9 0.027198091 1.6 1531 6 6 6 8 8 9 N N N N N N NDUFB1 high in P 3.9 0.027198091 1.6 1532 4 4 4 6 7 7 N N N N N N SLC19A1 high in P 3.2 0.027239686 1.6 1533 56 35 35 102 131 87 N N N N N N LOC283856 high in P 2.8 0.027281964 1.6 1534 26 38 65 102 101 140 NA NA N N N N NPM3 high in P 3.6 0.027288783 1.6 1535 347 101 167 600 855 486 N N N N N N THAP7 high in P 3.4 0.027318104 1.6 1536 86 150 21 422 283 202 N N N N N N RRAGA high in P 3.4 0.027384248 1.6 1537 896 382 461 2747 1546 1357 N N N N N N EXD2 high in P 5.4 0.027431299 1.6 1538 84 18 18 165 121 69 NA NA N N N N ISLR2 high in P 2.7 0.027444937 1.6 1539 48 32 28 93 61 75 N N N N P P RANBP2 high in P 3.0 0.027451756 1.6 1540 39 50 41 91 86 136 N N N N N N RHOF high in P 5.0 0.027586771 1.6 1541 15 13 17 21 101 84 N N N N N N C6orf203 high in P 7.9 0.027599045 1.6 1542 19 2 2 18 14 10 N N N N N N ZNF558 high in P 3.3 0.027635186 1.6 1543 3 27 18 78 46 40 N N N N N N APBB3 high in P 6.5 0.027693147 1.6 1544 61 14 15 64 52 117 N N N N N N LOC254559 high in P 6.0 0.027699966 1.6 1545 19 8 8 120 13 33 P P N N N N MYLK3 high in P 3.3 0.027741562 1.6 1546 36 26 27 78 58 96 P N N N N N DDX46 high in P 2.2 0.02774838 1.6 1547 72 97 86 215 201 159 N N N N N N POMGNT1 high in P 3.9 0.02778043 1.6 1548 139 53 86 451 319 163 N N N N N N MTA3 high in P 2.7 0.02781998 1.6 1549 169 62 127 272 316 396 N N N N N N KIAA0101 high in P 2.9 0.027826798 1.6 1550 3 3 3 6 21 6 N N N N N N WDR27 high in P 5.3 0.027903171 1.6 1551 9 14 9 55 14 65 N N N N N N RAB3A high in P 8.7 0.028003409 1.6 1552 101 14 7 76 119 364 N N N N N N IDH3A high in P 2.5 0.028030003 1.6 1553 46 87 71 175 148 126 N N N N N N RGS14 high in P 3.7 0.02805046 1.6 1554 62 15 17 45 142 153 N N N N N N DENND1A high in P 3.8 0.028127514 1.6 1555 182 39 91 755 322 271 N N N N N N KCTD13 high in P 3.0 0.028141152 1.6 1556 112 60 81 282 248 173 N N N N N N FAM40B high in P 3.2 0.028160245 1.6 1557 28 17 23 37 59 57 N N N N P N PARP16 high in P 3.6 0.028223662 1.5 1558 58 9 22 64 59 142 N N N N N N DPYSL4 high in P 3.7 0.028275486 1.5 1559 95 36 58 125 195 244 P N N N N N C19orf47 high in P 2.9 0.028282305 1.5 1560 18 15 30 38 41 57 N N N N N N LOC339047 high in P 3.9 0.028351858 1.5 1561 8 21 30 32 57 87 N N N N N N RPTOR high in P 3.5 0.028418684 1.5 1562 77 30 93 203 290 148 NA NA N N N N RHD high in P 2.9 0.028555063 1.5 1563 75 63 107 190 172 185 N N N N N N KIAA1755 high in P 3.0 0.028580293 1.5 1564 28 20 23 50 46 39 N N N N N N C8orf73 high in P 10.2 0.028601432 1.5 1565 43 8 8 42 56 74 N N N N N N MDK high in P 7.1 0.02861507 1.5 1566 650 86 233 641 1531 1894 N N N N N N CCNL1 high in P 2.5 0.028630753 1.5 1567 542 393 581 1127 1415 2121 N N N N N N POLD1 high in P 3.7 0.028637572 1.5 1568 36 12 28 84 73 63 N N N N N N EHMT2 high in P 4.9 0.028644391 1.5 1569 176 25 61 492 222 250 N N N N N N SLAMF1 high in P 3.0 0.02870849 1.5 1570 27 18 24 61 40 121 N N N N N N SYN2 high in P 4.1 0.028715309 1.5 1571 25 13 19 32 64 53 P P N N N N ASF1B high in P 4.5 0.028728946 1.5 1572 3 3 4 7 21 6 N N N N N N HUNK high in P 3.5 0.028735765 1.5 1573 95 30 57 194 150 159 N N N N N N FLJ42627 high in P 3.7 0.02882032 1.5 1574 42 40 52 104 119 128 N N N N N N PPP1R9B high in P 5.2 0.028827139 1.5 1575 573 85 219 705 1045 1592 N N N N N N FTSJ3 high in P 2.7 0.028840777 1.5 1576 66 116 98 284 189 284 N N N N N N GDAP2 high in P 5.2 0.028941016 1.5 1577 52 27 35 104 119 93 N N N N N N NHEDC2 high in P 4.4 0.02895329 1.5 1578 122 30 45 234 178 173 N N N N N N NCOR1 high in P 2.6 0.028960109 1.5 1579 127 75 116 314 258 269 N N N N P N AKIRIN2 high in P 2.3 0.028979202 1.5 1580 653 571 659 1341 1380 1964 N N N N N N INPP5F high in P 2.4 0.029008524 1.5 1581 72 54 57 141 94 128 N N N N N N IQCC high in P 2.7 0.029015343 1.5 1582 19 25 25 34 43 47 N N N N N N SFRS16 high in P 3.7 0.029072622 1.5 1583 70 42 125 252 245 177 N N N N N N PAFAH1B3 high in P 2.6 0.029095124 1.5 1584 25 14 24 47 49 34 N N N N N N CYP2E1 high in P 3.1 0.029101943 1.5 1585 10 4 4 6 9 10 N P N N N N GGA3 high in P 3.0 0.029140811 1.5 1586 12 24 41 71 78 50 N N N N N N ASH1L high in P 2.7 0.029168769 1.5 1587 110 84 116 317 219 419 N N N N N N UBE2Q1 high in P 2.6 0.029182407 1.5 1588 114 70 70 296 308 148 N N N N N N SLC4A2 high in P 2.8 0.029221957 1.5 1589 65 115 62 311 172 184 N N N N N N HM13 high in P 3.2 0.029237641 1.5 1590 206 110 145 758 493 299 N N P N N N ADNP2 high in P 2.5 0.029253324 1.5 1591 80 73 109 217 197 240 N N N N N N SLC22A23 high in P 3.8 0.029307876 1.5 1592 145 64 94 646 228 247 N N N N N N POLN high in P 2.9 0.029329697 1.5 1593 5 5 5 9 10 8 N N N N N N GPCPD1 high in P 2.5 0.029349472 1.5 1594 32 64 48 99 100 127 NA NA N N N N CNBP high in P 3.1 0.029403341 1.5 1595 567 268 269 1039 975 1519 N N N N N N RNF121 high in P 3.1 0.029425844 1.5 1596 9 14 11 41 23 19 N N N N N N C3orf74 high in P 5.5 0.029441527 1.5 1597 18 7 8 29 21 18 N N N N N N RELB high in P 2.8 0.029472895 1.5 1598 516 262 707 1596 1136 1560 N N N N N N RANBP9 high in P 4.6 0.029551995 1.5 1599 471 128 192 917 575 1214 N N N N N N DEF8 high in P 2.4 0.029573133 1.5 1600 139 142 158 376 284 435 N N N N N N XIRP1 high in P 6.4 0.029601091 1.5 1601 16 40 55 46 213 306 N N N N N N MRE11A high in P 4.2 0.029613365 1.5 1602 8 8 8 16 13 11 N N N N N N SFRS2IP high in P 2.2 0.029687692 1.5 1603 32 84 94 196 178 198 N N N N N N LAS1L high in P 2.5 0.029694511 1.5 1604 128 115 175 323 370 244 N P N N N N FSD1 high in P 42.9 0.02972315 1.5 1605 5 5 5 56 5 61 N N N N N N PPP1R13L high in P 3.2 0.029826798 1.5 1606 158 252 375 531 1985 765 N N P N N N ZNF740 high in P 3.8 0.029924991 1.5 1607 19 15 14 43 29 24 N N N N N N HNRNPH3 high in P 3.7 0.029993863 1.5 1608 587 413 560 1967 877 4395 N N N N N N BTBD3 high in P 2.8 0.030000682 1.5 1609 14 9 12 29 24 18 N N N N N N C20orf12 high in P 2.8 0.030077736 1.5 1610 7 13 8 28 21 18 N N N N N N MLEC high in P 3.6 0.030105694 1.5 1611 777 295 303 1309 1113 1854 N N N N N N FHL3 high in P 3.5 0.030112513 1.5 1612 400 78 258 662 935 865 N N N N N N TNKS2 high in P 3.4 0.030189567 1.5 1613 101 103 105 184 417 387 N N N N N N USP20 high in P 3.1 0.030203205 1.5 1614 20 51 37 105 61 111 N N N N N N LIME1 high in P 3.7 0.030210024 1.5 1615 30 9 46 64 53 105 N N N N N N BTBD10 high in P 2.3 0.030291851 1.5 1616 94 39 69 161 158 146 N N N N N N DGKD high in P 3.2 0.030305489 1.5 1617 114 85 143 252 511 275 N N N N P N TUFM high in P 3.5 0.030312308 1.5 1618 574 607 102 2098 1196 1408 N N N N N N ZNF248 high in P 3.7 0.030333447 1.5 1619 13 16 36 57 38 133 N N N N N N ATAD3A high in P 4.2 0.030358677 1.5 1620 45 51 119 212 248 147 N N N N P N MLL4 high in P 3.1 0.030379134 1.5 1621 137 73 123 269 455 356 N N N N N N LOH12CR2 high in P 2.9 0.030398227 1.5 1622 15 5 9 33 30 20 N N N N N N APOD high in P 2.6 0.030405046 1.5 1623 19469 15851 20460 37057 50152 194951 N N N N N N UBL4A high in P 4.2 0.030411865 1.5 1624 182 19 70 480 265 226 N N N N N N GPATCH8 high in P 2.7 0.030447324 1.5 1625 22 34 40 91 94 99 N N N N N N SLC13A4 high in P 3.3 0.030454143 1.5 1626 9 22 11 22 29 41 N N N N N N LONP2 high in P 2.4 0.03046778 1.5 1627 55 60 74 114 121 157 N N N N N N SEPX1 high in P 3.5 0.030474599 1.5 1628 52 44 31 242 133 57 N N N N N N USH1G high in P 3.0 0.030503921 1.5 1629 9 13 19 22 45 35 P P N N N N POU2F2 high in P 4.7 0.030531197 1.5 1630 11 32 23 145 35 193 P N N P N N FAM110A high in P 3.5 0.030543471 1.5 1631 39 16 45 75 142 65 N N N N N N ABHD3 high in P 4.1 0.030578929 1.5 1632 6 29 12 27 45 93 N N N N N N LAYN high in P 2.8 0.03060075 1.5 1633 21 25 14 40 51 29 N N N N N N RNF40 high in P 3.6 0.030621207 1.5 1634 34 23 28 107 71 69 N N N N N N CSK high in P 2.6 0.03064371 1.5 1635 429 356 454 1212 1277 849 N N N N N N FAM184B high in P 3.3 0.030656666 1.5 1636 442 330 625 993 1024 1933 P N N N N N NFXL1 high in P 3.9 0.030713945 1.5 1637 10 15 19 48 48 18 N N N N N N POLR2A high in P 4.3 0.030741902 1.5 1638 1476 600 466 3089 2098 2598 N N N N N N THAP3 high in P 3.0 0.030767815 1.5 1639 5 22 35 63 92 43 N N N N N N MRPS16 high in P 2.4 0.03080941 1.5 1640 129 112 158 312 410 319 N N N N N N LOC284276 high in P 2.9 0.030831913 1.5 1641 4 4 4 15 7 13 N N N N N N MAD2L1BP high in P 4.4 0.03085987 1.5 1642 43 11 48 250 58 152 N N N N N N TMEM63C high in P 3.7 0.030866689 1.5 1643 6 6 8 11 27 14 P N N N N N PCYOX1 high in P 8.7 0.03090283 1.5 1644 127 27 21 215 163 148 N N N N N N HSPBAP1 high in P 4.7 0.030923287 1.5 1645 8 21 52 86 75 60 N N N N N N PSPN high in P 3.4 0.030945107 1.5 1646 2 5 11 17 15 36 N N N N N N TELO2 high in P 2.7 0.031008524 1.5 1647 27 35 55 139 92 64 N N N N N N INPP4A high in P 2.8 0.031074668 1.5 1648 95 63 99 178 268 418 N N N N N N MTMR10 high in P 2.9 0.031110808 1.5 1649 203 63 145 457 336 397 N N N N N N HAPLN4 high in P 5.3 0.031124446 1.5 1650 7 7 7 33 28 7 N P N N N N ALDOA high in P 2.7 0.031155131 1.5 1651 4194 3317 6045 16150 12581 8407 N N N N N N TAF1A high in P 3.4 0.031248551 1.5 1652 13 10 5 35 15 14 N N N N P N LIPE high in P 4.8 0.031289465 1.5 1653 25 13 17 53 43 21 N N N N N N AGFG2 high in P 2.3 0.031318104 1.5 1654 25 19 23 57 41 42 N N N N N N DENND5A high in P 2.8 0.031333788 1.5 1655 580 367 235 1092 922 1561 N N N N N N LOC440335 high in P 6.8 0.031366519 1.5 1656 19 31 93 121 839 87 NA NA N N N N C1orf9 high in P 2.5 0.031440846 1.5 1657 30 59 57 142 104 79 N N N N N N PRRX2 high in P 3.3 0.03145312 1.5 1658 777 168 515 1487 1086 2633 N N N N P N FXYD2 high in P 4.2 0.031459939 1.5 1659 19 9 13 70 47 24 N N N N N N CYTH2 high in P 3.0 0.031466758 1.5 1660 610 349 304 1076 1304 1002 N N N N N N CINP high in P 3.1 0.031486533 1.5 1661 60 18 28 80 151 60 N N N N N N KIAA0892 high in P 2.4 0.031529492 1.5 1662 209 166 190 734 528 379 N N N N N N LPAR2 high in P 3.1 0.03154313 1.5 1663 51 42 34 117 110 74 N N N N N N QPRT high in P 3.1 0.03161882 1.5 1664 52 19 16 97 51 90 N N N N N N BAIAP2 high in P 3.6 0.031641323 1.5 1665 233 314 546 732 1388 2118 N N N N N N WDR77 high in P 2.4 0.031749744 1.5 1666 103 85 103 231 489 187 N N N N N N RNF207 high in P 4.2 0.031801568 1.5 1667 17 17 13 49 23 68 N N N N N N CHIC1 high in P 2.8 0.031828162 1.5 1668 19 26 18 31 54 47 N N N N N N EXOSC2 high in P 2.8 0.031834981 1.5 1669 51 98 66 141 151 153 N N N N N N PKLR high in P 4.7 0.031918173 1.5 1670 4 4 5 6 15 10 N N N N N N TRAPPC2 high in P 3.4 0.03196045 1.5 1671 17 12 12 20 33 51 N N N N N N TMBIM1 high in P 3.0 0.031996591 1.5 1672 1506 931 2171 6123 3645 3117 N N N N N N ESRP2 high in P 3.1 0.03202523 1.5 1673 12 18 31 37 275 59 NA NA N N N N EP400 high in P 2.4 0.032059325 1.5 1674 120 124 83 226 246 293 N N N N N N CENPBD1 high in P 3.2 0.032078418 1.5 1675 9 9 13 15 18 22 NA NA N N N N PTAR1 high in P 2.1 0.032092056 1.5 1676 114 117 122 274 217 260 N N N N N N SSR2 high in P 3.0 0.032105694 1.5 1677 1275 506 735 3714 2036 1816 N N N N N N HIVEP1 high in P 3.2 0.032136379 1.5 1678 66 45 26 102 81 176 N N N N N N RRP15 high in P 2.2 0.032143198 1.5 1679 51 50 49 110 122 103 N N N N N N ZNF222 high in P 6.4 0.032177293 1.5 1680 2 14 2 22 18 12 N P N N N N SBF1P1 high in P 2.5 0.03219775 1.5 1681 252 96 186 415 522 413 NA NA N N N N ZNF614 high in P 4.2 0.03225162 1.5 1682 13 45 17 59 73 53 N N N N N N TRAF7 high in P 3.3 0.032289124 1.5 1683 707 247 274 1630 1509 859 N N N N N N WDR34 high in P 4.4 0.032418002 1.5 1684 73 15 40 155 160 69 N N N N N N LOC100128239 high in P 2.8 0.03243164 1.5 1685 5 5 5 13 8 15 NA NA N N N N PCDHB19P high in P 8.4 0.032446642 1.5 1686 24 8 8 28 24 34 N N N N N N GCET2 high in P 3.9 0.032497784 1.5 1687 8 8 8 10 24 11 N P N N N N UMPS high in P 3.2 0.032504603 1.5 1688 5 41 20 54 81 83 N N N N N N SDS high in P 8.8 0.032540061 1.5 1689 3 13 8 26 12 161 P N N N N N PBX3 high in P 5.0 0.032555745 1.5 1690 36 27 12 40 93 109 N N P N N N ANKS4B high in P 3.0 0.03258643 1.5 1691 282 238 490 856 1072 637 N N N N N N SLC43A1 high in P 3.5 0.032638936 1.5 1692 47 31 67 145 80 212 N N N N N N DIO3OS high in P 4.6 0.03270508 1.5 1693 3 3 7 24 6 32 N N N N N N PTBP1 high in P 5.8 0.032730992 1.5 1694 1454 212 327 2014 2158 2010 N N N N N N VEZF1 high in P 2.3 0.032737811 1.5 1695 250 219 221 517 567 817 N N N N N N PDK1 high in P 2.2 0.032760314 1.5 1696 70 58 72 155 123 104 N N N N P N MINA high in P 3.3 0.032767133 1.5 1697 103 63 29 185 167 183 N N P N N N PPP3CC high in P 3.4 0.032797136 1.5 1698 270 117 140 639 439 357 N N N N N N TAF11 high in P 2.6 0.032842823 1.5 1699 165 169 92 394 252 395 N N N N N N SH2D3A high in P 2.9 0.032895329 1.5 1700 25 34 27 44 81 109 N P N N N N UBE2Q2P3 high in P 6.2 0.032902148 1.5 1701 NA NA NA NA NA NA NA NA N N N N SRFBP1 high in P 2.7 0.03298193 1.5 1702 17 30 19 53 67 43 N N N N N N CTNS high in P 4.5 0.033004432 1.5 1703 71 22 29 152 123 69 N N N N N N THG1L high in P 3.2 0.033043982 1.5 1704 14 15 18 81 45 21 N N N N N N CADPS2 high in P 4.0 0.033138084 1.5 1705 17 16 12 26 37 46 N N N N N N MAN1A1 high in P 3.4 0.03315104 1.5 1706 104 39 51 177 146 255 N N N N N N MOV10L1 high in P 2.7 0.033171497 1.5 1707 1 1 1 3 14 4 P N N N N N C6orf173 high in P 3.3 0.033178316 1.5 1708 NA NA NA NA NA NA N N N N N N NPHP4 high in P 3.0 0.033323559 1.5 1709 31 17 37 57 50 76 N N N N N N SERPINB6 high in P 2.9 0.033490624 1.5 1710 489 144 391 1450 778 864 N N N N N N ARHGEF2 high in P 2.4 0.03353222 1.5 1711 127 130 204 333 358 481 N N N N N N ALOXE3 high in P 2.8 0.033562905 1.5 1712 9 9 10 12 12 15 N N N N N P PRDX3 high in P 3.9 0.033569724 1.5 1713 460 136 224 2080 859 496 N N N N N N PPP1R16B high in P 6.1 0.033643369 1.5 1714 61 15 19 57 58 382 P N N N P N UHRF1 high in P 3.2 0.033678145 1.5 1715 35 17 37 46 79 104 N N N N N N CR1 high in P 3.7 0.033691783 1.5 1716 5 6 8 31 14 10 P N N N N N SLC15A2 high in P 3.5 0.03378793 1.5 1717 13 15 18 41 25 38 N N N N N N IVD high in P 2.8 0.033837709 1.5 1718 35 36 45 128 95 76 N N N N N N SEC22B high in P 2.8 0.033869076 1.5 1719 207 78 137 617 354 295 P N N N P N BCAT2 high in P 3.1 0.033897034 1.5 1720 181 79 207 365 350 590 N N N N N P ATP5L2 high in P 3.9 0.033978861 1.5 1721 9 2 3 8 10 5 NA NA N N N N 10-Sep high in P 2.9 0.03398568 1.5 1722 3583 1238 2858 10496 7420 4915 NA NA N N N N HELB high in P 5.0 0.034042278 1.5 1723 14 8 8 16 29 18 N P N N N N TCEA3 high in P 2.8 0.034083191 1.5 1724 6 13 16 22 26 38 N N N N N N UBL7 high in P 3.2 0.034110467 1.5 1725 87 29 73 272 140 124 N N N N N N DFFB high in P 3.4 0.034124105 1.5 1726 6 24 8 39 22 31 N N N N N N RAI14 high in P 4.1 0.034216843 1.5 1727 367 91 125 741 926 353 N N N N N N C17orf80 high in P 4.2 0.03428776 1.5 1728 40 11 18 33 50 55 N N N N N N KLHL26 high in P 2.8 0.034306853 1.5 1729 25 35 47 84 60 222 N N N N N N ALDH1L2 high in P 3.2 0.034336175 1.5 1730 52 25 31 70 83 72 N N N N N N KLB high in P 4.9 0.034357995 1.5 1731 9 11 16 17 33 86 N N N N N N C14orf79 high in P 3.7 0.034412547 1.5 1732 21 11 6 52 32 15 N N N N N N FCGBP high in P 5.3 0.034433004 1.5 1733 8 8 21 34 15 109 N P N N N N SSSCA1 high in P 2.7 0.034488919 1.5 1734 102 105 200 479 521 210 N N N N N N CRBN high in P 2.1 0.034585748 1.5 1735 36 48 46 84 74 100 N N N N N N TULP4 high in P 2.7 0.034627344 1.5 1736 67 59 94 151 240 164 N N N N N N MEGF8 high in P 3.7 0.03477327 1.5 1737 53 36 43 151 113 81 N N N N N N IL23A high in P 4.9 0.034786226 1.5 1738 11 23 43 96 40 100 N N N N N N C15orf63 high in P 2.7 0.034814183 1.5 1739 121 301 185 420 654 478 NA NA N N N N KIAA2018 high in P 4.6 0.034884419 1.5 1740 190 87 42 418 260 326 N N N N N N ZNF276 high in P 3.1 0.034951926 1.5 1741 54 40 51 95 141 166 N N N N N N ASB16 high in P 4.0 0.034958745 1.5 1742 10 5 8 43 35 10 N P N N N N ARID3B high in P 2.8 0.034977838 1.5 1743 9 11 13 26 23 17 N N N N N N STARD5 high in P 4.3 0.035016706 1.5 1744 51 5 15 52 41 127 N N N N N N C1orf21 high in P 2.8 0.035045346 1.5 1745 423 228 241 682 725 854 N N N N N N FAM159A high in P 4.5 0.035058984 1.5 1746 2 2 3 7 5 39 N N N N N N NCRNA00114 high in P 6.5 0.035071258 1.5 1747 18 2 2 36 26 7 NA NA N N N N FBXL18 high in P 4.0 0.035112172 1.5 1748 39 39 38 91 95 147 N N N N N N MFSD11 high in P 5.2 0.035132629 1.5 1749 146 26 42 215 170 209 N N N N N N TUSC4 high in P 2.8 0.035256052 1.5 1750 NA NA NA NA NA NA N N N N N N ZNF668 high in P 4.0 0.035299011 1.5 1751 35 29 92 122 115 117 N N N N N N NDUFA3 high in P 3.6 0.035324923 1.5 1752 301 99 145 1062 766 258 N N N N N N C10orf67 high in P 3.2 0.035347426 1.5 1753 9 9 9 29 14 12 N N N N N N USF2 high in P 4.0 0.0354388 1.5 1754 205 62 73 397 236 309 N N N N N N ABRA high in P 4.4 0.035466758 1.5 1755 28 3 22 22 89 72 N N N N N N ZBTB8OS high in P 5.2 0.035487214 1.4 1756 11 19 14 83 37 18 N N N N N N LOC100133957 high in P 3.4 0.035511763 1.4 1757 69 19 34 132 72 100 NA NA N N N N PCYT1A high in P 2.8 0.035565632 1.4 1758 5 5 6 9 10 30 N N N N N N BRSK2 high in P 3.6 0.035610638 1.4 1759 4 4 5 31 15 7 P N N N N N HARS high in P 2.6 0.035629731 1.4 1760 131 85 171 297 421 244 N N N N N N MRPS26 high in P 2.7 0.035652233 1.4 1761 288 288 177 569 737 451 N N N N N N CLASP1 high in P 2.5 0.035659052 1.4 1762 63 69 96 313 153 184 N N N N N N TAF8 high in P 3.1 0.035801568 1.4 1763 20 54 25 87 65 71 N N N N N N BBS4 high in P 2.4 0.035837027 1.4 1764 21 14 19 38 23 28 N N N N N N MSH5 high in P 2.8 0.035843846 1.4 1765 7 7 8 14 10 18 N N N N N N NFYA high in P 3.3 0.035907262 1.4 1766 342 129 177 645 500 773 N N N N P N FAM125A high in P 3.3 0.035938629 1.4 1767 59 33 73 236 112 89 N N N N N N PPIL2 high in P 2.8 0.035969997 1.4 1768 80 36 102 238 208 121 N P N N N N ZDHHC11 high in P 3.0 0.035983635 1.4 1769 6 17 13 27 18 36 P N N N N N CLIC2 high in P 2.4 0.035990453 1.4 1770 84 78 92 211 163 572 N N N N N N SLAMF7 high in P 3.8 0.036006137 1.4 1771 4 4 6 21 7 20 N P N N N N SLC34A2 high in P 5.5 0.036026594 1.4 1772 13 70 126 259 2106 129 P P N N N N PPEF2 high in P 3.2 0.036033413 1.4 1773 4 12 5 14 13 22 N N P N N N PSCA high in P 8.4 0.036062734 1.4 1774 4 4 4 4 46 12 N N N N N N CUL4A high in P 3.4 0.036092738 1.4 1775 206 159 458 631 910 943 N N N N N N ASZ1 high in P 3.5 0.036099557 1.4 1776 20 15 40 61 53 47 N N N N N N HOXC8 high in P 3.5 0.036137743 1.4 1777 194 51 38 654 102 550 N N N N N N TAOK2 high in P 2.5 0.036260484 1.4 1778 113 80 137 243 366 280 N N N N N N C4orf10 high in P 3.7 0.03645687 1.4 1779 53 18 21 80 48 96 N N N N N N TMC5 high in P 2.6 0.036477327 1.4 1780 34 36 60 85 94 82 P P N N N N HCN2 high in P 2.9 0.036497784 1.4 1781 7 8 10 11 19 83 P P N N N N XAF1 high in P 4.0 0.036563928 1.4 1782 36 22 25 46 46 133 N N N N N N BRSK1 high in P 3.1 0.036610297 1.4 1783 43 20 22 141 41 86 N N N N N N IRF5 high in P 2.7 0.036638936 1.4 1784 194 88 123 319 348 299 N N N N N N RHBDF2 high in P 2.8 0.036664848 1.4 1785 9 12 16 23 53 22 N N N N N N KRT80 high in P 3.9 0.036702353 1.4 1786 25 50 90 100 445 164 N N N N N N NCRNA00174 high in P 3.2 0.036722128 1.4 1787 13 14 14 22 20 31 NA NA N N N N TLN2 high in P 2.7 0.036768496 1.4 1788 25 39 27 88 47 96 N N N N N N PELP1 high in P 2.5 0.036869417 1.4 1789 368 347 234 828 1113 553 N N N N N N ABCA7 high in P 2.7 0.036975793 1.4 1790 28 32 37 66 56 62 N N N N N N HNRPLL high in P 2.2 0.036982612 1.4 1791 126 98 109 256 221 401 N N N N P N FAM38A high in P 2.9 0.036998295 1.4 1792 155 283 513 672 976 1109 NA NA N N N N NLRP1 high in P 4.3 0.037011933 1.4 1793 39 17 17 60 58 93 N N N N N N SPATA2 high in P 2.2 0.037041255 1.4 1794 161 134 105 340 286 296 N N N N N N FLJ44635 high in P 3.1 0.037110808 1.4 1795 6 9 11 14 20 22 P N N N N N RNF145 high in P 2.4 0.037131947 1.4 1796 368 507 318 814 958 1316 N N N N N N TBCD high in P 2.6 0.037138766 1.4 1797 13 21 30 55 35 71 N N N N N N PSMB7 high in P 3.2 0.037284691 1.4 1798 445 850 264 2201 945 1448 N N N N N N TMEM104 high in P 3.1 0.037306512 1.4 1799 32 25 35 134 81 38 N N N N N N FAM100A high in P 3.4 0.03732015 1.4 1800 98 168 368 415 630 935 N N N N N N NLRP12 high in P 2.4 0.037326969 1.4 1801 31 27 38 58 55 78 N N N N N N MANBA high in P 4.7 0.037333788 1.4 1802 7 7 7 15 7 18 N N N N N N PER1 high in P 3.1 0.037364473 1.4 1803 960 691 2345 5071 2194 5545 N N N N N N CCDC136 high in P 2.8 0.03745312 1.4 1804 31 20 27 34 33 61 N N N N N N CSPP1 high in P 3.5 0.037480395 1.4 1805 17 58 52 63 164 161 N N N N N N LRRC33 high in P 4.0 0.037569724 1.4 1806 3 3 4 9 6 24 N N N N N N PLCB3 high in P 5.1 0.037617457 1.4 1807 24 8 9 38 17 28 N N N N N N ZBTB7C high in P 6.0 0.037648142 1.4 1808 97 22 18 50 138 201 N N N N N N VAMP1 high in P 2.7 0.037699284 1.4 1809 22 20 15 34 24 45 N N N N N N LOC349196 high in P 2.9 0.037739516 1.4 1810 59 38 36 90 83 309 NA NA N N N N NOL11 high in P 3.3 0.037800205 1.4 1811 33 19 50 82 100 45 N N N N N N TTC39A high in P 4.3 0.037939993 1.4 1812 6 6 6 11 15 6 N N N N N N TIE1 high in P 6.5 0.037946812 1.4 1813 246 13 58 424 256 306 N N N N N N PORCN high in P 4.0 0.037987044 1.4 1814 40 25 17 165 33 77 P N N N N N NUAK2 high in P 2.9 0.038035459 1.4 1815 6 12 7 22 18 12 N N N N N N MACC1 high in P 3.7 0.038057961 1.4 1816 34 27 32 64 64 59 N N N N N N EMR1 high in P 8.6 0.03806478 1.4 1817 2 2 2 10 2 117 N P N N N N C7orf40 high in P 2.1 0.038071599 1.4 1818 792 646 751 1278 1693 1595 N N N N N N R3HDM1 high in P 3.7 0.038162973 1.4 1819 17 11 12 20 40 18 N N N N N N SLC25A3 high in P 3.2 0.038169792 1.4 1820 275 90 155 539 477 338 N N N N N N DOCK7 high in P 2.5 0.038176611 1.4 1821 26 39 52 66 91 73 N N N N N N THTPA high in P 3.9 0.038226389 1.4 1822 30 6 10 82 35 20 N N N N P N DYSFIP1 high in P 4.7 0.038280259 1.4 1823 2 2 3 7 4 17 N N N N N N GPN2 high in P 3.2 0.038295943 1.4 1824 17 34 29 52 93 46 N N N N N N PCDHB15 high in P 3.0 0.038308217 1.4 1825 32 7 5 41 17 47 N N N N N N POLR2L high in P 2.5 0.038346403 1.4 1826 365 447 599 1928 959 937 N N N N N N SLC25A25 high in P 3.4 0.03836686 1.4 1827 1108 418 451 1421 1426 3004 N N N N N N IPP high in P 3.7 0.038396181 1.4 1828 35 15 18 64 46 50 N N N N N N HOOK1 high in P 3.8 0.038451415 1.4 1829 29 32 17 39 75 33 P P N N N N C16orf67 high in P 3.4 0.038542107 1.4 1830 6 21 15 41 54 21 N N N N N N RIC8A high in P 2.8 0.038548926 1.4 1831 170 95 154 504 330 242 N N N N N N FOXO1 high in P 2.9 0.038625298 1.4 1832 412 396 267 1630 635 1297 N N N N N N POLE3 high in P 2.4 0.038645755 1.4 1833 30 31 41 73 67 101 N N N N N N MCM4 high in P 2.2 0.038710535 1.4 1834 18 29 29 50 62 36 N N N N N N RASSF6 high in P 3.2 0.038733038 1.4 1835 84 37 50 142 129 86 N P N N N N RPF1 high in P 3.3 0.038793727 1.4 1836 44 48 121 202 135 168 NA NA N N N N CC2D1A high in P 4.2 0.038821684 1.4 1837 16 18 19 66 57 21 N N N N N P MUS81 high in P 2.7 0.038833958 1.4 1838 78 88 161 271 252 190 N N N N N N FAM173A high in P 4.2 0.038908967 1.4 1839 105 33 26 113 120 127 N N N N N N LTA high in P 3.6 0.038990794 1.4 1840 4 4 5 6 7 12 N N N N N N ILF2 high in P 2.2 0.039141493 1.4 1841 786 1076 929 1586 2312 1984 N N N N N N TRMU high in P 2.6 0.039169451 1.4 1842 25 33 16 56 43 38 N N N N N N LASS1 high in P 6.4 0.039208319 1.4 1843 7 1 2 3 19 28 N N N N N N PTDSS2 high in P 3.8 0.039215138 1.4 1844 132 57 45 247 144 187 N N N N N N GMPS high in P 2.4 0.039404705 1.4 1845 139 86 87 322 324 153 N N N N N N FAM189A2 high in P 3.8 0.039459257 1.4 1846 28 13 11 27 127 18 NA NA N N N N POM121L10P high in P 3.3 0.03951449 1.4 1847 24 21 25 38 63 62 NA NA N N N N PIAS3 high in P 2.3 0.039534947 1.4 1848 151 81 115 379 234 229 N N N N N N ATOX1 high in P 4.4 0.039560859 1.4 1849 377 84 162 843 755 332 N N N N N N AP2S1 high in P 4.0 0.039590863 1.4 1850 765 175 307 3204 1354 655 N N N N P N ADAT2 high in P 6.4 0.039603819 1.4 1851 50 16 17 48 63 77 N N N N N N CDK5R1 high in P 2.3 0.039692465 1.4 1852 21 28 32 50 46 58 N N N N N N SHROOM3 high in P 2.8 0.039729969 1.4 1853 91 93 154 252 897 219 N N N N N N CASKIN1 high in P 2.4 0.03974838 1.4 1854 102 80 116 302 237 171 N N N N N N LOX high in P 3.3 0.039760655 1.4 1855 184 80 163 732 556 222 N N N N N N DPY19L3 high in P 2.8 0.039776338 1.4 1856 13 25 43 129 54 46 N N N N N N SRCRB4D high in P 3.5 0.03980225 1.4 1857 9 5 9 8 27 15 N N N N N N RSL1D1 high in P 2.3 0.039912717 1.4 1858 66 116 91 202 214 299 N N N N N N ACRBP high in P 15.4 0.03998568 1.4 1859 2 2 2 21 2 18 N N N N N N IPO13 high in P 2.9 0.040009547 1.4 1860 28 27 52 50 104 116 N N N N N N MT1A high in P 3.0 0.040035459 1.4 1861 88 75 277 187 610 747 N N N N N N IRX4 high in P 4.2 0.040131606 1.4 1862 7 36 50 98 186 39 N N N N N N NCRNA00115 high in P 7.6 0.040216843 1.4 1863 2 3 5 24 4 61 N N N N N N SAPS3 high in P 2.2 0.040484828 1.4 1864 299 246 270 633 509 966 N N N N N N RPL21P44 high in P 3.9 0.040582339 1.4 1865 9 11 15 14 37 39 NA NA N N N N PAQR7 high in P 2.7 0.040606887 1.4 1866 386 97 240 656 672 594 N N N N N N PPAP2B high in P 3.3 0.040619161 1.4 1867 2532 2360 1241 14204 4339 4068 N N N N N N FARS2 high in P 4.1 0.040751449 1.4 1868 36 11 29 114 43 39 N N N N N N C19orf25 high in P 2.7 0.040777361 1.4 1869 62 31 60 152 157 75 N N N N N N PPP1R14B high in P 2.3 0.04085987 1.4 1870 2 4 5 8 19 8 N N N N N N TRIM8 high in P 3.0 0.040878964 1.4 1871 1254 707 440 2605 1370 3539 N N N N N N MIR132 high in P 4.7 0.040934197 1.4 1872 1 1 2 3 6 31 NA NA N N N N OSBPL3 high in P 3.9 0.040941016 1.4 1873 24 35 42 43 107 135 N N N N N N TMC4 high in P 3.8 0.041011251 1.4 1874 94 32 108 106 621 309 N N N N N N PHF1 high in P 3.6 0.041039209 1.4 1875 565 381 781 2151 931 3180 N N N N N N TGFB2 high in P 5.3 0.041052847 1.4 1876 142 149 157 208 899 1230 N N N N P N PLAG1 high in P 4.7 0.041115581 1.4 1877 6 6 6 11 6 16 P P N N N N C20orf96 high in P 4.4 0.041144903 1.4 1878 93 19 33 87 125 124 N N N N N N FAM118A high in P 2.7 0.04116536 1.4 1879 30 18 23 46 38 47 N N N N N N RELL2 high in P 8.6 0.041267644 1.4 1880 4 4 4 54 4 20 N N N N N N SERHL high in P 3.8 0.041286737 1.4 1881 8 2 12 13 20 14 N N N N N N LGR5 high in P 6.5 0.04130583 1.4 1882 4 4 4 4 24 10 N P N N N N ADAMTS10 high in P 3.6 0.041312649 1.4 1883 223 39 102 235 357 726 N N N N N N TTF2 high in P 2.0 0.0413597 1.4 1884 18 24 28 47 37 38 N N N N N N TUBGCP6 high in P 2.4 0.04141357 1.4 1885 70 70 136 212 218 186 N N N N N N GRB7 high in P 4.3 0.041442891 1.4 1886 35 87 142 251 865 120 P N N N N N SH3RF2 high in P 2.7 0.04144971 1.4 1887 20 16 22 32 80 29 N N N N N N PODNL1 high in P 4.5 0.041524719 1.4 1888 9 9 9 15 14 22 N N N N N N LOC400891 high in P 3.3 0.041536993 1.4 1889 12 12 13 18 18 21 NA NA N N N N TUBGCP2 high in P 3.4 0.041570406 1.4 1890 247 70 169 898 464 273 N N N N N N GNAZ high in P 3.5 0.041605182 1.4 1891 24 39 30 55 204 49 N N N P N N METTL14 high in P 2.8 0.041663144 1.4 1892 11 6 7 24 10 13 NA NA N N N N MGAT5B high in P 3.1 0.041676781 1.4 1893 6 8 7 10 20 34 P N N N N N TAOK3 high in P 2.5 0.041721105 1.4 1894 58 134 112 302 202 286 N N N N N N LDHC high in P 5.7 0.041774974 1.4 1895 3 3 3 3 18 9 N N N N N N ACVRL1 high in P 3.5 0.041798159 1.4 1896 192 57 66 573 181 322 N N N N N N C10orf35 high in P 5.3 0.042049096 1.4 1897 9 19 21 85 224 14 P N N N N N BCL2L1 high in P 2.8 0.042070235 1.4 1898 617 329 573 2313 1358 857 N N N N N N TOPORS high in P 3.1 0.042098875 1.4 1899 32 95 69 131 144 277 N N N N N N GPRC5C high in P 3.0 0.042119332 1.4 1900 65 34 116 215 171 138 N N N N N N ARAP2 high in P 4.8 0.042169792 1.4 1901 28 12 14 18 90 35 N N N N N N FAM122B high in P 2.8 0.04221207 1.4 1902 43 28 21 123 58 50 N N N N N N DHCR7 high in P 2.6 0.042244801 1.4 1903 95 47 50 276 233 85 N N N N N N HEATR1 high in P 2.7 0.042281623 1.4 1904 66 135 79 171 374 182 N N N N N N GRPEL1 high in P 2.5 0.042294579 1.4 1905 296 479 220 684 1071 1003 N N N N N N ADAM32 high in P 4.9 0.042310263 1.4 1906 5 5 5 5 16 10 N N N N N N PIGZ high in P 2.3 0.042317081 1.4 1907 26 27 26 35 45 47 N N N N P N PIPOX high in P 3.5 0.042330038 1.4 1908 12 13 7 11 22 26 P N N N N N AHCTF1 high in P 2.1 0.04237777 1.4 1909 62 78 59 129 123 99 N N N N N N PHPT1 high in P 2.6 0.042418684 1.4 1910 520 305 481 1387 1276 685 N N N N N N ADAM15 high in P 3.7 0.042553017 1.4 1911 43 96 148 143 470 377 N N N P N N LOC440896 high in P 2.9 0.042569383 1.4 1912 16 34 70 183 71 80 N N N N N N ACADVL high in P 3.7 0.042636209 1.4 1913 1194 1064 3511 6572 4787 3742 N N N N N N MICALL1 high in P 3.6 0.042643028 1.4 1914 109 38 117 339 423 128 N N N N N N SNF8 high in P 3.0 0.042724855 1.4 1915 155 93 253 742 368 302 N N N N N N RGL3 high in P 3.8 0.042731674 1.4 1916 13 16 18 62 47 17 N N N N N N ACTR8 high in P 2.5 0.042750767 1.4 1917 37 28 27 85 46 48 N N N N N N HGS high in P 2.4 0.042763723 1.4 1918 450 425 580 2221 1169 818 N N N N N N ERC1 high in P 2.4 0.042788953 1.4 1919 151 129 179 418 324 281 N N N N N N VSTM2L high in P 2.2 0.042795772 1.4 1920 4 4 4 6 7 7 N N N N P N AP1G2 high in P 2.3 0.04285237 1.4 1921 27 50 67 88 131 85 N N N N N N RAC3 high in P 2.6 0.042864644 1.4 1922 16 4 4 11 17 9 N N N N N N TBK1 high in P 2.2 0.042937607 1.4 1923 13 33 44 100 57 63 N N N N N N EML3 high in P 2.6 0.043279918 1.4 1924 186 48 113 486 240 265 N N N N N N GLG1 high in P 4.3 0.043429935 1.4 1925 1397 245 491 3377 1452 2422 N N N N N N CD96 high in P 3.1 0.043440164 1.4 1926 19 11 9 16 18 33 N N N N N N TRIM3 high in P 2.8 0.043446983 1.4 1927 69 57 157 241 193 243 N N N N N N DUSP2 high in P 3.2 0.043564269 1.4 1928 583 209 188 401 1841 1780 N N N N N N ZCCHC10 high in P 2.8 0.043591544 1.4 1929 17 23 11 30 30 23 N N N N N N TMEM132E high in P 4.7 0.043643369 1.4 1930 3 6 8 28 8 35 P P N N N N PCNA high in P 2.6 0.043650188 1.4 1931 243 123 168 404 418 311 N N N N N N C21orf91 high in P 6.2 0.043681555 1.4 1932 157 25 33 198 194 186 N N N N N N NUBP2 high in P 2.9 0.043705421 1.4 1933 6 30 9 41 39 22 N N N N N N STMN1 high in P 2.8 0.043717695 1.4 1934 201 123 282 379 588 750 N N N N N N SMC3 high in P 2.4 0.043755881 1.4 1935 45 93 54 190 135 106 N P N N N N EMILIN3 high in P 3.0 0.0437627 1.4 1936 18 7 8 20 11 24 N N N N N N DGKI high in P 3.4 0.043804296 1.4 1937 5 5 5 9 12 5 P N N N N N MSI2 high in P 2.2 0.04386703 1.4 1938 56 46 32 79 75 99 N N N N P N RANGAP1 high in P 2.0 0.043913399 1.4 1939 276 366 362 653 747 813 N N N N N N NDE1 high in P 3.2 0.043932492 1.4 1940 51 34 20 87 57 86 N N N N N N ZNF329 high in P 3.0 0.043939311 1.4 1941 41 23 16 48 68 40 N N N N N N LEPRE1 high in P 2.7 0.043982953 1.4 1942 15 20 11 46 33 37 N N N N N N C8orf41 high in P 2.9 0.044019775 1.4 1943 11 27 52 151 54 64 N N N N N N NOG high in P 6.2 0.044032049 1.4 1944 13 11 7 9 91 49 P N N N N N STRN4 high in P 2.5 0.044077736 1.4 1945 328 143 498 735 1004 872 N N N N N N KLRC3 high in P 6.6 0.044091374 1.4 1946 2 2 4 5 10 39 N N N N N N KCNMB1 high in P 4.9 0.044098193 1.4 1947 26 15 9 27 84 20 N N N N N N LRRC1 high in P 3.1 0.04414388 1.4 1948 10 11 18 23 80 22 N N N N P N AP1M1 high in P 3.5 0.044270713 1.4 1949 513 163 226 1856 960 420 N N N N N N ARHGDIA high in P 3.2 0.04429867 1.4 1950 2110 889 2731 6672 7314 3065 N N N N N N UGT2B10 high in P 12.2 0.044333788 1.4 1951 2 2 2 16 14 2 N N N N N N XIST high in P 2.0 0.044381862 1.4 1952 468 545 637 1243 1242 1420 N N N N N N NAT10 high in P 2.4 0.044437777 1.4 1953 100 185 109 269 388 236 N N N N N N AKR7A3 high in P 2.1 0.044444596 1.4 1954 19 8 11 19 20 15 N N N N N N TGDS high in P 4.5 0.044451415 1.4 1955 4 14 6 67 24 10 N N N N N N C12orf5 high in P 3.1 0.044579611 1.4 1956 72 52 36 114 121 117 N N N N N N MSL3 high in P 2.8 0.04460075 1.4 1957 78 35 40 105 99 186 N N N N N N RARRES3 high in P 3.6 0.044630072 1.4 1958 157 50 81 120 447 533 N N N N N N LOC284100 high in P 2.8 0.044699625 1.3 1959 4 9 10 23 20 12 N N N N N N EBF4 high in P 3.8 0.044711899 1.3 1960 147 45 66 210 255 176 N N N N N N RXRB high in P 2.4 0.044778725 1.3 1961 175 149 274 423 390 549 N N N N N N LOC90784 high in P 3.5 0.044893965 1.3 1962 26 33 24 90 157 28 NA NA N N N N PYGO1 high in P 7.1 0.044900784 1.3 1963 3 3 4 3 21 70 N N N N N N NKTR high in P 2.2 0.044914422 1.3 1964 122 130 189 624 315 328 N N N N N N C2orf54 high in P 4.7 0.044994886 1.3 1965 66 32 18 41 319 104 N N N N N N C1orf216 high in P 3.8 0.045181043 1.3 1966 108 36 34 139 114 137 N N N N N N CD55 high in P 2.7 0.045260143 1.3 1967 209 522 315 1022 763 882 N N N N P N SGSM2 high in P 2.7 0.045457893 1.3 1968 135 77 229 294 571 327 N N N N N N IL10RA high in P 3.9 0.045498125 1.3 1969 49 19 10 68 41 158 P N N N N N DNAJC22 high in P 2.0 0.045561541 1.3 1970 110 93 105 170 164 230 N P N N N N GMPPB high in P 3.8 0.04556836 1.3 1971 58 34 39 292 131 47 N N N N N N RRP9 high in P 2.9 0.045657006 1.3 1972 43 115 272 307 663 271 N N N N N N MRPL16 high in P 4.8 0.045663825 1.3 1973 148 21 23 296 192 87 N N N N N N CLCN5 high in P 2.7 0.045682919 1.3 1974 44 30 33 82 56 59 N P N N N N PRIC285 high in P 2.9 0.045719059 1.3 1975 21 21 38 50 75 79 N N N N N N CENPL high in P 2.5 0.045789976 1.3 1976 9 15 21 25 26 22 N N N N N N CCT4 high in P 2.2 0.045841118 1.3 1977 39 19 25 50 68 49 N N N N N N CCNF high in P 2.5 0.045966587 1.3 1978 31 14 31 41 70 47 N N N N N N PPFIA1 high in P 1.9 0.046034095 1.3 1979 221 227 241 453 569 404 N N N N P N SP140L high in P 2.4 0.046040914 1.3 1980 134 37 109 258 237 207 N N N N N N RBM43 high in P 3.3 0.046094102 1.3 1981 20 13 9 47 20 26 N N N N N N PITPNM3 high in P 4.2 0.046297988 1.3 1982 36 12 20 34 62 63 P N N N N N TSEN2 high in P 2.2 0.04632731 1.3 1983 8 9 9 12 13 17 N N N N N N MTL5 high in P 2.1 0.046370269 1.3 1984 11 15 24 44 34 29 N N N N N N C9orf9 high in P 4.3 0.046423457 1.3 1985 34 2 4 16 19 48 N N N N N N PLA2G4C high in P 2.7 0.046471872 1.3 1986 39 46 76 114 82 177 N N N N N N TNRC18 high in P 4.2 0.04650733 1.3 1987 453 80 157 981 442 606 N N P N N N C6orf41 high in P 3.1 0.046572792 1.3 1988 2 15 9 29 33 14 NA NA N N N N C9orf95 high in P 2.6 0.046579611 1.3 1989 39 11 8 62 20 53 N N N N N N FAM50A high in P 2.9 0.046622571 1.3 1990 102 97 227 471 256 332 N N N N N N NAA10 high in P 2.9 0.046666894 1.3 1991 350 152 335 1248 911 392 NA NA N N N N ZSWIM1 high in P 3.2 0.046794408 1.3 1992 13 19 34 38 35 84 N N N N N N ATL1 high in P 3.2 0.046826458 1.3 1993 21 11 12 21 23 22 N N N N N N SLC24A6 high in P 3.3 0.046867371 1.3 1994 68 110 248 337 339 326 N N N N N N LTC4S high in P 5.4 0.046901466 1.3 1995 29 3 3 16 27 20 N N N N N N DCAF15 high in P 3.7 0.046927378 1.3 1996 13 6 10 39 27 9 NA NA N N N N E4F1 high in P 5.3 0.046934197 1.3 1997 10 10 11 33 29 22 N N N N N N STAG3L1 high in P 2.2 0.04699284 1.3 1998 18 28 19 70 31 40 N N N N N N CLN6 high in P 3.4 0.047060348 1.3 1999 33 55 154 177 295 170 N N N N N N TMEM91 high in P 3.2 0.047073986 1.3 2000 42 19 20 39 57 130 N N N N N N CEBPD high in P 2.8 0.047087624 1.3 2001 2787 4101 5050 5651 11363 15003 N N N N N N MASTL high in P 2.7 0.047434708 1.3 2002 41 52 21 87 55 121 N N N N P N HBS1L high in P 3.9 0.047441527 1.3 2003 65 32 34 99 82 104 N N N N N N MFSD10 high in P 2.6 0.047549949 1.3 2004 834 312 745 1795 2196 1034 N N N N N N KIAA0495 high in P 2.4 0.047572451 1.3 2005 29 30 20 81 46 43 P N N N N N PTMS high in P 3.0 0.04764746 1.3 2006 2526 693 1383 3896 3356 3972 N N N N N N ZC3H10 high in P 2.8 0.047718377 1.3 2007 17 6 6 22 11 11 N N N N N N SNX32 high in P 2.6 0.047747699 1.3 2008 4 4 4 8 9 4 N N N N N N C1orf174 high in P 2.6 0.04781657 1.3 2009 6 7 7 18 14 9 N N N N N N LRRC20 high in P 3.3 0.047829526 1.3 2010 50 5 15 33 52 127 N N N N N N WDR67 high in P 3.0 0.047875895 1.3 2011 7 7 7 13 7 13 N N N N N N RNF167 high in P 3.9 0.047882714 1.3 2012 501 119 184 802 690 556 N N N N N N MAP2K5 high in P 2.4 0.047896352 1.3 2013 58 20 58 109 67 115 N N N N N N TRAT1 high in P 5.8 0.047914081 1.3 2014 2 2 2 6 2 93 N N N N N N EFNB3 high in P 6.2 0.04802864 1.3 2015 190 38 18 153 202 278 N N N N N N WDR20 high in P 2.2 0.048062734 1.3 2016 31 48 43 77 67 90 N N N N N N FOXE3 high in P 12.8 0.048160586 1.3 2017 1 1 1 18 19 1 P N N N N N FITM1 high in P 3.8 0.048291851 1.3 2018 10 5 13 12 17 17 NA NA N N N N CLDN10 high in P 3.7 0.0483164 1.3 2019 5 6 7 7 21 15 N N N N N N C14orf176 high in P 4.2 0.048331401 1.3 2020 4 8 4 6 23 84 NA NA N N N N FNIP1 high in P 2.1 0.048372315 1.3 2021 124 192 195 538 366 515 N N N N N N APLN high in P 3.3 0.048393454 1.3 2022 17 10 13 40 31 13 N P N N N N ANKRD42 high in P 4.3 0.048461643 1.3 2023 18 7 8 23 12 28 N N N N N N LOC100129550 high in P 2.6 0.048488237 1.3 2024 14 17 22 48 36 22 N N N N N N CHMP7 high in P 2.1 0.048508012 1.3 2025 9 18 11 27 23 20 N N N N N N ATP6V0A1 high in P 3.1 0.048570747 1.3 2026 152 84 307 610 349 724 N N N N N N POLD2 high in P 2.6 0.048577566 1.3 2027 50 111 70 378 186 105 N N N N N N ZNF529 high in P 4.4 0.048613024 1.3 2028 33 37 29 50 98 90 N N N N N N SFRS6 high in P 2.0 0.048750767 1.3 2029 253 152 298 584 563 624 N N N N N N LOC100190938 high in P 3.1 0.048766451 1.3 2030 18 32 14 42 30 40 N N N N N N MAST3 high in P 5.4 0.048805319 1.3 2031 112 24 12 260 41 348 N P N N N N HCST high in P 5.4 0.049029662 1.3 2032 13 7 14 9 38 113 N N N N N N C1orf144 high in P 2.1 0.049112854 1.3 2033 143 208 194 579 500 355 N N N N N N UBE2M high in P 2.7 0.049187862 1.3 2034 11 15 19 38 43 18 N N N N N N CEP135 high in P 3.5 0.049210365 1.3 2035 11 11 11 27 19 11 N N N N N N C19orf39 high in P 2.4 0.049217184 1.3 2036 6 29 21 42 30 40 N N N N N N NPAT high in P 2.6 0.049515854 1.3 2037 14 40 17 38 55 77 N N N N N N UBE2Z high in P 2.4 0.049556086 1.3 2038 1184 956 853 2981 1542 2744 N N N N N N VARS2 high in P 2.2 0.049608592 1.3 2039 66 65 90 126 123 108 N N N N N N FLII high in P 3.3 0.049629049 1.3 2040 204 335 65 892 804 344 N N N N N N SNCG high in P 3.4 0.04964405 1.3 2041 56 13 19 37 117 57 N N N N N N ARSD high in P 2.1 0.049650869 1.3 2042 143 175 155 359 276 403 N N N N N N RBM10 high in P 2.3 0.049691101 1.3 2043 489 307 369 865 680 1119 N N N N N N POT1 high in P 3.0 0.049723832 1.3 2044 9 9 10 11 21 17 N N N N N N IFFO1 high in P 3.3 0.049753836 1.3 2045 171 21 72 245 166 418 N N N N N N EN2 high in P 2.9 0.049784521 1.3 2046 17 55 38 56 91 166 P P N N N N LOC374443 high in P 3.4 0.049812479 1.3 2047 6 12 7 12 11 39 N N N N N N SNHG12 high in P 2.9 0.049905898 1.3 2048 5 12 15 16 29 35 N N N N N N C1orf59 high in P 2.9 0.049919536 1.3 2049 5 6 5 15 8 13 N N N N N N MICA high in P 2.5 0.04994613 1.3 2050 113 133 84 280 140 422 N N N N N N

TABLE 16 Genes that Are Differentially Methylated between Nulliparous and Parous CD24+ Breast Epithelial Cells SAGE−seq ChIP-seq MSDK-seq log10 Nuliiparous (NP) Parous (P) NP P NP P NP P expression Fold (P- CD24+ CD24+ CD24+ CD24+ CD24+ CD24+ CD24+ CD24+ GeneBody GeneBody Pro-moter Pro-moter Gene Symbol pattern Change p-value val.) Rank-ing N48 N58 N43 N37 N39 N40 N74 N66 NP Met Met Met C9orf16 high in NP −2.4 0.0499928 −1.3 13183 168 86 177 33 66 91 N N N N N N TRIM56 high in NP −2.0 0.049894062 −1.3 13184 31 84 34 26 17 24 N N N N N N MED25 high in NP −1.7 0.049887891 −1.3 13185 135 87 56 47 49 33 N N N N N N ENOSF1 high in NP −2.0 0.049828922 −1.3 13186 126 229 161 104 115 66 N N N N N N LPPR3 high in NP −1.8 0.049768582 −1.3 13187 6 17 17 6 6 6 NA NA N N N N NDUFA9 high in NP −1.8 0.049752811 −1.3 13188 478 586 575 316 424 217 N N N N N N LOC151162 high in NP −1.7 0.04972607 −1.3 13189 49 63 43 30 31 33 N N N N N N NAT15 high in NP −2.1 0.049577276 −1.3 13190 57 198 82 30 46 49 N N N N N N TTYH1 high in NP −3.4 0.049514194 −1.3 13191 247 132 545 37 88 151 N N N N N N SLC25A5 high in NP −2.6 0.049416827 −1.3 13192 799 594 383 146 329 340 N N N N N N ERCC1 high in NP −2.0 0.049267348 −1.3 13193 333 672 373 197 201 304 N N N N N N INPP5E high in NP −2.2 0.049237863 −1.3 13194 16 38 27 8 8 19 N N N N N N ABCB8 high in NP −1.8 0.049168609 −1.3 13195 102 112 76 65 52 50 N N N N N N ROBO3 high in NP −2.1 0.049137068 −1.3 13196 135 158 228 63 91 110 P P N N N N COX6C high in NP −2.7 0.04912404 −1.3 13197 91 35 34 11 31 16 N N N N N N CCDC9 high in NP −1.8 0.049100041 −1.3 13198 94 72 129 37 58 49 N N N N N N ISCU high in NP −2.1 0.048993075 −1.3 13199 60 63 30 27 24 29 N N N N N N NIT1 high in NP −1.7 0.048807255 −1.3 13200 30 35 21 16 16 15 N N N N N N BAD high in NP −2.5 0.048801083 −1.3 13201 97 174 280 92 69 58 N N N N N N SCO2 high in NP −2.6 0.048753771 −1.3 13202 261 456 127 99 115 112 N N N N N N GOLM1 high in NP −2.4 0.0487476 −1.3 13203 398 604 216 192 192 137 N N N N N N HINT1 high in NP −1.6 0.048741429 −1.3 13204 99 108 83 70 43 59 N N N N N N ANTXR1 high in NP −2.0 0.048635148 −1.3 13205 30 52 28 21 24 21 N N N N N N RP9P high in NP −2.0 0.048583722 −1.3 13206 6 13 11 6 6 6 N N N N N N RHBDL2 high in NP −1.6 0.048535038 −1.3 13207 623 856 816 441 537 474 N N N N N N NACC1 high in NP −1.7 0.048389674 −1.3 13208 181 232 203 123 162 81 N N N N N N APH1A high in NP −1.7 0.048331391 −1.3 13209 134 322 197 120 95 113 N N N N N N MAGED2 high in NP −2.3 0.048278593 −1.3 13210 799 1109 453 412 360 378 N N N N N N CCT8 high in NP −2.2 0.04796455 −1.3 13211 471 1414 829 402 346 457 N N N N N N VASP high in NP −2.8 0.047947408 −1.3 13212 53 132 152 40 53 55 N N N N P N C9orf86 high in NP −2.3 0.047941237 −1.3 13213 222 940 480 226 226 178 N N N N N N NDST2 high in NP −4.2 0.04788364 −1.3 13214 45 174 205 41 59 36 N N N N N N PGAP2 high in NP −1.6 0.047821242 −1.3 13215 67 34 31 18 15 15 NA NA N N N N SLC22A17 high in NP −2.0 0.04778353 −1.3 13216 242 255 330 108 141 213 N N N N N N CDIPT high in NP −1.6 0.047701934 −1.3 13217 60 64 47 33 40 31 N N N N N N TNKS1BP1 high in NP −2.3 0.047627194 −1.3 13218 612 1585 1185 432 455 710 N N N N N N KIAA0652 high in NP −2.4 0.047621023 −1.3 13219 116 115 53 44 32 42 N N N N N N C19orf22 high in NP −1.9 0.047589482 −1.3 13220 1430 2004 3103 803 1192 1270 N N N N N N C14orf28 high in NP −2.3 0.047535998 −1.3 13221 15 24 16 14 6 6 N N N N N N MBIP high in NP −1.7 0.047476344 −1.3 13222 62 55 36 29 28 26 N N N N P N PRKCI high in NP −1.7 0.047448917 −1.3 13223 93 121 107 34 64 71 N N N N N N SMG1 high in NP −2.4 0.047395433 −1.3 13224 244 208 132 88 82 134 N N N N N N H6PD high in NP −1.6 0.047362521 −1.3 13225 51 118 64 43 44 36 N N N N N N RBM42 high in NP −2.0 0.04735155 −1.3 13226 93 98 75 15 56 38 N N N N N N NCRNA00095 high in NP −3.4 0.047328922 −1.3 13227 468 455 148 117 112 158 N N N N N N ZNF134 high in NP −1.6 0.047296695 −1.3 13228 42 25 19 17 17 18 N N N N N N SFRS17A high in NP −3.8 0.047290524 −1.3 13229 245 77 142 49 83 45 N N N N N N CTBP2 high in NP −1.5 0.047233612 −1.3 13230 71 58 57 37 42 39 N N N N N N KCTD5 high in NP −1.9 0.047144473 −1.3 13231 10 18 12 10 6 6 N N N N N N SLC7A8 high in NP −1.9 0.04713076 −1.3 13232 120 203 172 96 118 64 N N N N N N LOC100190939 high in NP −2.2 0.046869515 −1.3 13233 512 313 184 85 156 168 N N N N N N ATF6 high in NP −1.8 0.046625411 −1.3 13234 17 22 13 9 9 12 N N N N N N LOC100144603 high in NP −4.1 0.046612383 −1.3 13235 1 3 5 1 1 1 N N N N N N HEXIM2 high in NP −1.8 0.046516388 −1.3 13236 7 6 4 5 2 2 N N N N N N WDR6 high in NP −1.9 0.046505417 −1.3 13237 157 170 150 54 84 120 N N N N N N ADAM11 high in NP −1.8 0.046479361 −1.3 13238 14 12 14 9 9 9 P P N N N N TGM4 high in NP −4.3 0.046466333 −1.3 13239 1 4 4 1 1 1 N N N N N N PYGM high in NP −2.7 0.046403936 −1.3 13240 24 23 34 12 12 23 N N N N N N AURKAIP1 high in NP −4.1 0.046323025 −1.3 13241 200 756 848 192 235 147 N N N N N N LOC642361 high in NP −5.8 0.046170118 −1.3 13242 4 18 33 4 4 4 NA NA N N N N EPHA10 high in NP −1.6 0.046128291 −1.3 13243 14 25 16 9 9 9 P P N N N N UPK3A high in NP −9.1 0.045874589 −1.3 13244 2 73 35 5 2 2 N N N N N N CDCA4 high in NP −2.2 0.045861561 −1.3 13245 50 74 33 17 17 38 N N N N N N SRPR high in NP −2.1 0.045784078 −1.3 13246 448 827 350 290 338 243 N N N N N N PHLDA3 high in NP −1.9 0.045772422 −1.3 13247 27 17 18 13 10 10 N N N N N N TRAF5 high in NP −1.9 0.045642828 −1.3 13248 35 34 27 16 25 16 N N N N N N USP53 high in NP −2.0 0.045610601 −1.3 13249 795 378 324 216 273 206 N N N N N N CCDC89 high in NP −4.3 0.045502263 −1.3 13250 2 5 8 2 2 2 N N N N N N C9orf21 high in NP −2.7 0.045443294 −1.3 13251 113 185 118 45 35 105 N N N N N N PLIN3 high in NP −1.8 0.045416552 −1.3 13252 675 1578 777 470 447 563 NA NA N N N N YPEL3 high in NP −1.7 0.045295187 −1.3 13253 194 361 270 169 146 175 N N N N N N TMC6 high in NP −2.0 0.045275302 −1.3 13254 106 231 198 105 84 96 N N N N N N NDUFB2 high in NP −1.7 0.045207419 −1.3 13255 311 484 389 238 278 153 N N N N N N AP1B1 high in NP −1.6 0.045161478 −1.3 13256 147 155 157 113 101 54 N N N N N N ATP6V1C2 high in NP −3.2 0.045051769 −1.3 13257 113 62 24 18 26 20 N P N N N P GBAS high in NP −2.9 0.044963316 −1.3 13258 48 35 13 9 9 9 N N N N N N PALLD high in NP −1.9 0.044903662 −1.3 13259 1425 1438 1244 664 845 1049 N N N N N N CHRNA10 high in NP −4.6 0.044835093 −1.3 13260 4 8 7 4 4 4 N N N N N N VPS28 high in NP −2.2 0.044828922 −1.3 13261 623 1258 1394 586 560 408 N N N N N N CCNY high in NP −1.7 0.044809037 −1.3 13262 145 171 130 108 81 89 N N N N N N TM9SF3 high in NP −2.0 0.044709613 −1.3 13263 257 634 228 163 146 159 N N N N N N GGT5 high in NP −2.1 0.04466093 −1.4 13264 41 58 76 38 30 23 N N N N N N NUP93 high in NP −4.4 0.044574534 −1.4 13265 30 201 172 16 47 28 N N N N N N TMEM168 high in NP −1.9 0.044532021 −1.4 13266 47 79 54 38 23 35 N N N N N N CCDC90A high in NP −1.8 0.044501166 −1.4 13267 13 11 25 7 5 8 N N N N N N CCDC157 high in NP −3.6 0.044371572 −1.4 13268 13 40 68 8 15 11 NA NA N N N N PACS2 high in NP −2.3 0.044331116 −1.4 13269 411 349 757 231 349 204 N N N N N N C14orf2 high in NP −2.7 0.04425432 −1.4 13270 199 115 66 27 64 52 N N N N N N API5 high in NP −2.0 0.044216607 −1.4 13271 35 59 29 18 20 26 N N N N N N KIAA0753 high in NP −2.5 0.044203579 −1.4 13272 17 26 22 9 19 9 N N N N N N THBS3 high in NP −2.8 0.044188494 −1.4 13273 170 102 310 85 61 74 N N N N N N ATP6V0E2 high in NP −1.9 0.044063014 −1.4 13274 87 118 128 80 32 54 N N N N N N EEF2 high in NP −1.9 0.043843596 −1.4 13275 27618 57739 47767 17418 23556 24703 N N N N N N SOX13 high in NP −1.6 0.043715373 −1.4 13276 31 55 58 29 29 27 N N N N N N ZNF454 high in NP −1.9 0.043567951 −1.4 13277 48 91 78 29 26 48 N N N N N N PARVB high in NP −2.2 0.043487041 −1.4 13278 100 168 120 54 101 46 N N N N N N MMP11 high in NP −4.6 0.043477441 −1.4 13279 6 13 9 6 6 6 N N N N N N FAM20A high in NP −2.4 0.043464413 −1.4 13280 58 55 31 21 27 30 N N N N P N S100A2 high in NP −2.8 0.0434363 −1.4 13281 125 302 291 34 110 123 N N N N N N RPPH1 high in NP −3.1 0.043421901 −1.4 13282 14 4 4 5 2 6 N N N N N N IER5 high in NP −2.6 0.043349904 −1.4 13283 1101 3072 2147 688 736 1221 N N N N N N VAPA high in NP −2.0 0.043213453 −1.4 13284 279 262 171 93 86 167 N N N N N N KIF1C high in NP −2.0 0.043176426 −1.4 13285 191 329 411 141 229 118 N N N N N N HIF1A high in NP −2.0 0.043046146 −1.4 13286 312 613 258 243 141 176 N N N N N N C21orf34 high in NP −5.9 0.042984435 −1.4 13287 53 10 32 9 14 12 N N N N N N POLR2D high in NP −2.3 0.042930952 −1.4 13288 45 100 121 39 35 39 N N N N N N LHPP high in NP −1.9 0.04290901 −1.4 13289 72 59 100 32 45 41 N N N N N N KLF13 high in NP −1.7 0.042888439 −1.4 13290 288 256 198 153 154 130 N N N N N N RAB13 high in NP −2.2 0.042875411 −1.4 13291 58 121 37 32 24 28 N N N N N N KCNAB3 high in NP −3.1 0.042769816 −1.4 13292 28 58 44 13 29 7 N N N N N N SRPRB high in NP −5.2 0.042707419 −1.4 13293 25 214 89 22 12 33 N N N N N N LOC390595 high in NP −5.6 0.042656679 −1.4 13294 6 35 57 6 8 6 NA NA N N N N GSTA1 high in NP −4.7 0.042650507 −1.4 13295 13 43 25 1 14 7 N N N N N N MAGOH high in NP −2.8 0.04262308 −1.4 13296 260 207 839 70 160 140 N N N N N N FAM128A high in NP −3.5 0.042546284 −1.4 13297 13 3 15 1 8 1 N N N N N N ZNF250 high in NP −2.3 0.042455088 −1.4 13298 135 90 88 38 38 74 N N N N N N BRD2 high in NP −2.0 0.042412575 −1.4 13299 1208 1023 650 568 460 577 N N N N N N HDAC10 high in NP −2.6 0.042392691 −1.4 13300 249 121 307 82 125 59 N N N N N N NR1H2 high in NP −2.1 0.042354292 −1.4 13301 672 1349 1383 572 654 360 N N N N N N DSP high in NP −2.4 0.042328922 −1.4 13302 1087 560 541 261 374 403 N N N N N N NDEL1 high in NP −1.6 0.042307666 −1.4 13303 35 33 37 23 17 18 N N N N N N PHF12 high in NP −1.6 0.04225624 −1.4 13304 252 336 234 156 177 183 N N N N N N GPX4 high in NP −1.9 0.042203442 −1.4 13305 6044 4408 7181 2246 3535 3302 N N N N N N CA13 high in NP −1.8 0.042173958 −1.4 13306 93 94 82 36 42 63 N N N N N N F5 high in NP −3.0 0.042158873 −1.4 13307 303 821 153 117 83 154 N N N N N N RABGEF1 high in NP −1.8 0.042079334 −1.4 13308 325 436 843 207 287 239 N N N N N N CYP51A1 high in NP −2.5 0.042003223 −1.4 13309 262 151 88 94 59 39 N N N N N N FAM116B high in NP −1.8 0.041983338 −1.4 13310 88 110 204 56 68 53 N N N N N N NDUFS6 high in NP −2.7 0.041942197 −1.4 13311 353 1089 760 308 347 279 N N N N N N ANAPC11 high in NP −2.2 0.041901742 −1.4 13312 669 1092 1482 567 605 331 N N N N N N DNAJC30 high in NP −1.8 0.041864715 −1.4 13313 72 114 101 62 62 41 N N N N N N YEATS4 high in NP −2.6 0.041851001 −1.4 13314 11 25 6 3 6 3 N N N N N N LRRC16B high in NP −3.9 0.041810546 −1.4 13315 11 45 20 12 6 6 N N N N N N FAM167B high in NP −5.3 0.041796832 −1.4 13316 2 6 6 2 2 2 N N N N N N RPN2 high in NP −2.3 0.041765291 −1.4 13317 141 200 94 72 90 65 N N N N N N UBE3A high in NP −2.1 0.04175912 −1.4 13318 98 241 180 60 65 125 N N N N N N PLXNB2 high in NP −2.1 0.041752948 −1.4 13319 1037 1963 1846 861 904 870 N N N N N N NUMBL high in NP −3.0 0.041734435 −1.4 13320 64 43 122 19 17 41 N N N N N N TRIO high in NP −1.5 0.041707008 −1.4 13321 493 851 626 417 422 391 N N N N N N CDK5RAP3 high in NP −2.6 0.041674095 −1.4 13322 153 51 27 12 17 26 N N N N N N SLAMF8 high in NP −1.9 0.041626783 −1.4 13323 40 18 21 12 12 11 N N N N N N CNOT4 high in NP −2.1 0.041537644 −1.4 13324 98 102 59 28 47 55 N N N N N N TNFSF14 high in NP −2.9 0.041495132 −1.4 13325 1660 1447 597 470 436 595 N N N N N N IRAK1 high in NP −2.7 0.041485532 −1.4 13326 322 1019 747 275 399 211 N P N N N N PKN1 high in NP −2.5 0.041465647 −1.4 13327 114 281 209 125 84 52 N N N N N N STK32C high in NP −2.1 0.04144302 −1.4 13328 48 88 135 29 38 38 N N N N N N FSD1L high in NP −1.8 0.041332625 −1.4 13329 13 12 14 8 11 8 N N N N N N DVL1 high in NP −2.1 0.04130314 −1.4 13330 123 81 143 36 50 62 N N N N N N NDUFAB1 high in NP −4.2 0.041258571 −1.4 13331 15 81 42 13 14 12 N N N N N N LOC643719 high in NP −5.3 0.041245543 −1.4 13332 1 6 5 1 1 1 NA NA N N N N CWC25 high in NP −1.7 0.041235943 −1.4 13333 58 46 38 28 22 28 NA NA N N N N MAML3 high in NP −2.6 0.041176975 −1.4 13334 17 65 52 21 19 17 N N P N N N CS high in NP −2.8 0.041170804 −1.4 13335 1222 1933 665 458 550 645 N N N N N N MRPL21 high in NP −3.4 0.041164632 −1.4 13336 36 20 10 5 10 14 N N N N N N NUP85 high in NP −3.1 0.041070008 −1.4 13337 34 100 50 12 31 27 N N N N N N PI15 high in NP −1.5 0.041008297 −1.4 13338 32 37 33 28 28 28 N N N N N N C1QTNF6 high in NP −1.7 0.040925329 −1.4 13339 24 28 27 12 15 15 N N N N N N MAP2K3 high in NP −2.6 0.040842704 −1.4 13340 2453 4001 1526 934 1100 1486 N N N N N N MAOA high in NP −2.9 0.040826591 −1.4 13341 50 27 20 19 11 17 N P N N N N SH3BGRL high in NP −2.8 0.04082042 −1.4 13342 99 98 40 19 36 29 N N N N N N DYRK4 high in NP −2.2 0.040814248 −1.4 13343 13 33 33 9 15 8 N N N N N N INTS7 high in NP −3.0 0.04075528 −1.4 13344 290 398 125 100 59 141 N N N N N N C1orf210 high in NP −2.5 0.040734709 −1.4 13345 52 34 31 10 23 19 N N N N N N LATS2 high in NP −2.3 0.040670941 −1.4 13346 218 231 127 56 85 119 N N N N N N LRPAP1 high in NP −2.8 0.040652427 −1.4 13347 19 44 27 12 18 16 N N N N N N FBRSL1 high in NP −2.6 0.040593459 −1.4 13348 209 448 514 145 231 178 NA NA N N N N SH2B1 high in NP −2.2 0.040535176 −1.4 13349 48 133 116 42 25 53 N N N N N N ING3 high in NP −2.1 0.040483064 −1.4 13350 30 55 65 25 14 26 N N N N N N RAD51L3 high in NP −1.9 0.040406267 −1.4 13351 24 21 21 10 10 16 N N N N N N MPPED2 high in NP −2.1 0.040356212 −1.4 13352 29 23 19 13 19 13 N N N N N N NEIL1 high in NP −4.4 0.040350041 −1.4 13353 144 34 35 7 22 23 N N N N N N RUSC2 high in NP −1.9 0.040212219 −1.4 13354 58 53 64 26 38 31 N N N N N N PDE4A high in NP −3.3 0.040199877 −1.4 13355 13 70 36 13 16 13 P P N N N P TMEM66 high in NP −2.3 0.040184106 −1.4 13356 228 99 68 31 45 55 N N N N N N ZFYVE27 high in NP −3.0 0.040171078 −1.4 13357 20 82 59 23 19 18 N N N N N N PFKFB3 high in NP −1.8 0.040153936 −1.4 13358 463 254 204 171 128 143 N N N N N N HABP4 high in NP −1.9 0.040125137 −1.4 13359 13 46 17 10 8 8 N N N N N N CCDC106 high in NP −2.5 0.040065483 −1.4 13360 17 52 47 11 8 21 N N P N N N HGD high in NP −4.6 0.040041484 −1.4 13361 17 6 4 1 8 1 N N N N N N C12orf45 high in NP −2.4 0.040035313 −1.4 13362 119 76 129 23 60 58 N N N N N N MAPK8 high in NP −1.8 0.039977715 −1.4 13363 10 14 11 6 6 9 N N N N N N ANXA11 high in NP −1.6 0.039771325 −1.4 13364 835 1315 937 620 706 610 N N N N N N DNAJC17 high in NP −3.2 0.039728812 −1.4 13365 41 118 232 19 37 35 N N N N N N C6orf72 high in NP −2.3 0.039698642 −1.4 13366 39 67 44 6 24 27 N N N N N N RPL28 high in NP −4.9 0.039619789 −1.4 13367 11337 15308 2908 2169 2333 3339 N N N N N N TOM1L2 high in NP −2.0 0.039613618 −1.4 13368 137 124 189 64 86 81 N N N N N N WBSCR26 high in NP −3.9 0.039586876 −1.4 13369 22 15 45 11 9 2 NA NA N N N N CTNNBL1 high in NP −2.0 0.039573848 −1.4 13370 81 225 111 57 45 71 N P N N N N MSRA high in NP −3.0 0.039499794 −1.4 13371 30 100 65 30 26 18 N N N N N N NUDC high in NP −2.3 0.039493623 −1.4 13372 941 1960 3253 639 825 824 N N N N N N CARKD high in NP −1.8 0.039455911 −1.4 13373 42 117 66 35 36 35 N N N N N N HLA-DOA high in NP −2.6 0.039295461 −1.4 13374 19 12 20 10 10 10 P N N N N N CDK7 high in NP −1.8 0.039263234 −1.4 13375 44 53 29 19 23 29 N N N N N N RICS high in NP −1.7 0.039206322 −1.4 13376 NA NA NA NA NA NA N N N N N N MTMR14 high in NP −2.3 0.039017759 −1.4 13377 45 42 23 9 21 18 N N N N N N OSCP1 high in NP −1.5 0.038966333 −1.4 13378 63 59 53 37 40 36 NA NA N N N N PCBP1 high in NP −1.9 0.038800398 −1.4 13379 356 203 138 81 106 103 N N N N N N CLIP1 high in NP −2.0 0.038720173 −1.4 13380 191 175 108 64 86 84 N N N N N N CXorf21 high in NP −2.3 0.038710573 −1.4 13381 41 35 25 25 14 13 N N N N N N IARS high in NP −2.5 0.038605664 −1.4 13382 646 604 292 248 257 223 N N N N N N ZNF773 high in NP −6.2 0.038599493 −1.4 13383 1 12 7 1 1 1 N N N N N N FAM174A high in NP −2.3 0.038546009 −1.4 13384 119 156 257 99 87 58 N N N N N N DIAPH1 high in NP −2.1 0.038327962 −1.4 13385 525 1507 539 286 320 405 N N N N N N CHERP high in NP −2.5 0.038179169 −1.4 13386 217 393 590 142 166 224 N N N N N N BOK high in NP −3.8 0.038061917 −1.4 13387 52 183 253 44 50 49 N N N N N N RELA high in NP −2.3 0.038018719 −1.4 13388 794 641 466 322 301 415 N N N N N N RCE1 high in NP −4.6 0.037842499 −1.4 13389 34 254 141 33 31 24 N N N N N N SIPA1L1 high in NP −1.8 0.037830156 −1.4 13390 153 231 149 124 94 82 N N N N N N TSPAN9 high in NP −2.5 0.037692334 −1.4 13391 35 39 69 28 21 15 N N N N N N FAM114A2 high in NP −1.6 0.03761828 −1.4 13392 10 10 8 6 6 6 N N N N N N PSME1 high in NP −2.0 0.037566854 −1.4 13393 768 651 439 311 338 348 N N N N N N CES2 high in NP −2.5 0.037560683 −1.4 13394 43 116 70 47 34 18 N N N N N N LOC113230 high in NP −6.7 0.037531884 −1.4 13395 1 7 8 1 1 1 N N N N N N SMPDL3B high in NP −3.6 0.03745783 −1.4 13396 18 30 25 16 12 6 N N N N N N GPX7 high in NP −2.7 0.037451659 −1.4 13397 21 28 33 5 19 11 N N N N N N VLDLR high in NP −2.1 0.037404347 −1.4 13398 19 34 29 15 17 7 N N N N N N B9D2 high in NP −2.3 0.037238412 −1.4 13399 22 24 21 17 8 9 N N N N N N ZFP91 high in NP −2.7 0.037197957 −1.4 13400 358 578 257 173 143 243 N N N N N N SETD1A high in NP −2.1 0.037012137 −1.4 13401 31 67 58 17 28 28 N N N N N N LOC644165 high in NP −7.4 0.036979909 −1.4 13402 2 22 8 2 2 2 N N N N N N CRIP1 high in NP −2.1 0.036855801 −1.4 13403 13 31 9 8 8 8 N N N N N N HLA-F high in NP −3.3 0.036804375 −1.4 13404 5725 11712 14618 5609 3587 727 N N N N N N GRTP1 high in NP −2.6 0.036745406 −1.4 13405 41 20 50 17 12 16 N N N N N N CYP4F11 high in NP −2.2 0.03672895 −1.4 13406 73 48 29 22 24 28 P N N N N N USP33 high in NP −1.7 0.036698094 −1.4 13407 60 131 65 49 38 39 N N N N N N CYB561D2 high in NP −2.7 0.036624726 −1.4 13408 44 114 47 29 32 16 N N N N N N CALY high in NP −7.4 0.036506788 −1.4 13409 3 13 10 3 3 3 P P N N N N ST5 high in NP −2.4 0.036500617 −1.4 13410 231 613 405 280 151 187 N N N N N N SEMA3G high in NP −3.2 0.036487589 −1.4 13411 81 33 37 13 13 31 N N N N N N GNMT high in NP −3.4 0.036436163 −1.4 13412 53 14 26 3 11 14 N N N N N N MLST8 high in NP −2.1 0.036421078 −1.4 13413 37 61 82 33 26 27 NA NA N N N N ZFX high in NP −2.7 0.036355252 −1.4 13414 52 77 32 28 32 17 N N N N N N MMP10 high in NP −3.0 0.03633331 −1.4 13415 6 17 16 6 6 6 N N N N N N CDK4 high in NP −1.7 0.036301083 −1.4 13416 29 42 33 13 22 23 N N N N N N CCDC130 high in NP −3.0 0.036274342 −1.4 13417 117 350 274 92 117 76 N N N N N N CPB1 high in NP −7.4 0.0362428 −1.4 13418 1 14 7 1 1 1 N N N N N N CDK10 high in NP −3.8 0.036139948 −1.4 13419 16 58 92 12 16 17 N N N N N N SIGIRR high in NP −2.5 0.036098121 −1.4 13420 128 346 220 93 97 103 N N N N N N CXorf26 high in NP −1.8 0.035991155 −1.4 13421 9 10 6 4 4 4 N N N N N N GALNT3 high in NP −1.7 0.035930129 −1.4 13422 100 72 58 40 38 46 N N N N N N C7orf36 high in NP −8.1 0.035626371 −1.4 13423 2 12 9 2 2 2 N N N N N N PRKCD high in NP −2.3 0.035467293 −1.5 13424 295 211 214 46 103 163 N N N N N N TRAPPC3 high in NP −1.7 0.035461122 −1.5 13425 85 112 105 38 59 67 N N N N N N KDELR1 high in NP −2.0 0.03544398 −1.5 13426 434 567 333 278 237 238 P P N N N N C18orf21 high in NP −2.3 0.035424095 −1.5 13427 16 21 11 4 11 7 N N N N N N ZNHIT2 high in NP −2.4 0.035417924 −1.5 13428 35 42 33 20 3 16 N N N N N N F11R high in NP −2.6 0.035386382 −1.5 13429 402 375 212 188 108 166 N N N N N N INTS1 high in NP −2.1 0.03537404 −1.5 13430 542 486 868 251 403 280 N N N N N N FTO high in NP −1.9 0.035329471 −1.5 13431 97 70 64 47 33 31 N N N N N N USP36 high in NP −2.6 0.035299986 −1.5 13432 233 344 390 91 150 218 N N N N N N GNL3 high in NP −2.4 0.035260217 −1.5 13433 135 200 113 50 63 106 N N N N N N RNASET2 high in NP −3.1 0.035128566 −1.5 13434 438 407 1950 138 238 270 N N N N N N XRCC1 high in NP −2.2 0.035017485 −1.5 13435 31 76 60 30 16 20 N N N N N N UBAP2 high in NP −1.7 0.035011314 −1.5 13436 23 56 49 19 25 18 N N N N N N C19orf42 high in NP −2.1 0.034990058 −1.5 13437 108 115 93 63 55 16 N N N N N N 40790 high in NP −5.1 0.034983886 −1.5 13438 58 19 101 8 13 24 NA NA N N N N SUCLG1 high in NP −1.8 0.034920804 −1.5 13439 584 445 417 250 274 309 N N N N N N PLRG1 high in NP −1.8 0.034822751 −1.5 13440 34 46 25 19 22 15 N N N N N N TRAF3 high in NP −1.8 0.03478641 −1.5 13441 39 67 45 27 25 34 N N N N N N NCBP2 high in NP −2.1 0.034667101 −1.5 13442 38 80 47 20 25 34 N N N N N N TACO1 high in NP −5.8 0.034610189 −1.5 13443 20 99 97 13 20 12 NA NA N N N N ZCCHC7 high in NP −3.2 0.034604018 −1.5 13444 15 45 17 7 7 15 N N N N N N MAST4 high in NP −2.2 0.034572477 −1.5 13445 164 439 287 131 140 172 N N N N N N NRAS high in NP −2.7 0.034524479 −1.5 13446 134 481 144 110 60 63 N N N N N N UFC1 high in NP −1.9 0.034518308 −1.5 13447 1525 1119 1526 777 737 805 N N N N N N G6PC high in NP −4.2 0.034512137 −1.5 13448 28 55 81 21 22 4 N N N N N N KIAA0895 high in NP −2.3 0.03430506 −1.5 13449 33 51 62 10 19 29 N N N N N N BACE2 high in NP −1.8 0.034276947 −1.5 13450 27 52 24 18 16 10 N N N N N N TUT1 high in NP −2.4 0.034244035 −1.5 13451 12 11 19 6 9 4 N N N N N N COMMD9 high in NP −1.9 0.034101413 −1.5 13452 144 114 132 79 87 56 N N N N N N ZNF211 high in NP −9.7 0.034095241 −1.5 13453 3 30 12 3 3 3 N N N N N N UXT high in NP −2.9 0.033989646 −1.5 13454 544 292 197 75 140 163 N P N N N N KDM1A high in NP −3.2 0.033918335 −1.5 13455 136 166 57 50 48 41 NA NA N N N N TAF5L high in NP −1.9 0.033905307 −1.5 13456 57 81 48 38 29 36 N N N N N N FBXO7 high in NP −2.6 0.033899136 −1.5 13457 26 54 27 25 10 13 N N N N P N NLRP8 high in NP −1.8 0.033797655 −1.5 13458 434 401 293 227 173 237 N N N N N N C11orf59 high in NP −3.0 0.033775713 −1.5 13459 40 95 47 27 28 14 N N N N N N ATP1A1 high in NP −2.3 0.033769542 −1.5 13460 1457 3000 1085 687 553 923 N N N N N N CMPK2 high in NP −2.2 0.033763371 −1.5 13461 17 33 26 13 15 11 N N N N N N KIAA0922 high in NP −2.9 0.033652976 −1.5 13462 72 39 22 16 19 22 N N N N N N CCL28 high in NP −2.2 0.033633091 −1.5 13463 37 35 16 7 18 11 N N N N N N EFCAB4A high in NP −4.4 0.033563151 −1.5 13464 423 112 224 22 42 131 N N N N N N PINX1 high in NP −9.8 0.033454813 −1.5 13465 3 23 13 3 3 3 N N N N N N STAT6 high in NP −2.5 0.03336636 −1.5 13466 499 1316 966 420 400 466 N N N N N N FBXO36 high in NP −1.7 0.033316991 −1.5 13467 39 42 28 22 24 21 N N N N N N ATP5F1 high in NP −4.0 0.03331082 −1.5 13468 249 239 71 66 36 66 N N N N N N ESRRA high in NP −4.0 0.033304649 −1.5 13469 219 728 755 203 220 169 N N N N N N RAB17 high in NP −2.6 0.033268308 −1.5 13470 144 284 338 172 64 59 N N N N N N CMAH high in NP −2.5 0.033239509 −1.5 13471 26 19 11 6 13 6 N N N N N N RDH13 high in NP −2.3 0.033114715 −1.5 13472 86 60 71 24 39 40 N N N N N N PTGES2 high in NP −1.7 0.033101001 −1.5 13473 12 19 21 9 10 7 N N N N N N CCDC112 high in NP −1.8 0.033085916 −1.5 13474 10 11 7 5 5 5 N N N N N N FGFR1OP2 high in NP −2.5 0.033042032 −1.5 13475 15 37 10 9 7 10 N N N N N N ARMC6 high in NP −3.6 0.033015976 −1.5 13476 63 169 242 41 48 64 N N N N N N SLC1A4 high in NP −1.8 0.032957693 −1.5 13477 36 79 51 34 26 16 N N N N N N BMP7 high in NP −2.2 0.032865126 −1.5 13478 323 211 361 165 124 159 P P N N N N SNRPD2 high in NP −2.9 0.032747189 −1.5 13479 546 288 285 88 164 207 N N N N N N RMND5A high in NP −1.6 0.032741018 −1.5 13480 87 111 119 72 77 60 N N N N N N ZNF20 high in NP −1.9 0.032673821 −1.5 13481 24 18 13 12 7 10 N N N N N N C11orf60 high in NP −2.1 0.032646393 −1.5 13482 NA NA NA NA NA NA N N N N N N HSD3B7 high in NP −3.6 0.032559312 −1.5 13483 36 149 136 40 31 29 N N N N N N PXN high in NP −2.0 0.032546284 −1.5 13484 148 110 106 54 67 75 N N N N N N IMPDH1 high in NP −1.8 0.032459888 −1.5 13485 298 413 666 190 228 237 N N N N N N VSIG2 high in NP −2.4 0.032441374 −1.5 13486 25 114 42 18 18 13 P P N N N N PMCHL2 high in NP −2.1 0.032348807 −1.5 13487 7 5 3 2 2 2 N N N N N N WDFY2 high in NP −2.0 0.032339207 −1.5 13488 93 73 95 46 48 49 N N N N N N NDUFAF3 high in NP −2.0 0.032237726 −1.5 13489 62 156 95 45 48 51 NA NA N N N N TMEM160 high in NP −2.6 0.032195214 −1.5 13490 78 144 252 71 53 40 N N N N N N CUL4B high in NP −2.2 0.032130074 −1.5 13491 44 43 27 15 25 21 N N N N N N MCL1 high in NP −2.2 0.032060134 −1.5 13492 2162 1719 1318 625 752 1172 N N N N N N C6orf154 high in NP −12.4 0.032053963 −1.5 13493 2 19 15 2 2 2 N N N N N N ROPN1 high in NP −2.5 0.031975795 −1.5 13494 9 2 6 1 4 4 N N N N N N CD276 high in NP −2.7 0.031957282 −1.5 13495 223 538 495 190 178 197 N N N N N N FAF2 high in NP −2.0 0.03193534 −1.5 13496 52 65 36 28 22 18 N N N N N N SLC2A4RG high in NP −2.2 0.031857858 −1.5 13497 40 67 47 20 36 14 N N N N N P METTL9 high in NP −2.3 0.031820831 −1.5 13498 53 32 17 9 14 14 N N N N N N LEMD2 high in NP −2.2 0.031805746 −1.5 13499 120 261 182 87 82 113 P N N N N N NR3C2 high in NP −2.0 0.031765976 −1.5 13500 36 47 27 18 19 22 N N N N P N TSC22D4 high in NP −2.2 0.031726207 −1.5 13501 116 235 178 102 50 80 N N N N N N HOOK2 high in NP −1.8 0.03168918 −1.5 13502 56 49 65 23 26 33 N N N N N N SSNA1 high in NP −5.0 0.03165421 −1.5 13503 100 456 565 98 113 37 N N N N N N MRPL55 high in NP −2.1 0.031630211 −1.5 13504 369 316 583 176 246 189 N N N N N N ATP10A high in NP −1.9 0.03159387 −1.5 13505 40 99 45 26 30 24 N N N N N N UBE2E2 high in NP −2.9 0.031587699 −1.5 13506 122 133 53 41 43 43 N N N N N N ARHGEF5 high in NP −2.5 0.031574671 −1.5 13507 435 474 957 202 223 365 N N N N N N TMEM110 high in NP −13.4 0.03153833 −1.5 13508 4 22 18 4 4 4 N N N N N N RETSAT high in NP −1.7 0.031485532 −1.5 13509 220 193 223 122 136 121 N N N N N N MRPS12 high in NP −3.9 0.031456733 −1.5 13510 44 265 107 31 41 25 N N N N N N DBNDD1 high in NP −3.0 0.031450562 −1.5 13511 113 383 341 129 85 58 N N N N N N CASZ1 high in NP −1.5 0.031402564 −1.5 13512 1006 901 1063 725 748 745 N N N P N N LOC100302652 high in NP −2.4 0.031396393 −1.5 13513 13 5 5 5 4 1 NA NA N N N N SAP30BP high in NP −3.2 0.031275713 −1.5 13514 138 408 297 95 107 136 N N N N N N UPF3A high in NP −2.3 0.031233886 −1.5 13515 88 121 63 51 46 24 N N N N N N C11orf66 high in NP −2.0 0.031134462 −1.5 13516 22 32 56 15 15 11 N N N N N N PRR23A high in NP −4.8 0.031100178 −1.5 13517 1071 366 214 41 85 243 NA NA N N N N DSC2 high in NP −3.7 0.031041895 −1.5 13518 859 733 306 195 239 287 N N N N N P CDC42BPG high in NP −1.6 0.031013782 −1.5 13519 15 20 22 12 10 10 N N N N N N UQCR11 high in NP −2.5 0.030998012 −1.5 13520 494 359 1337 221 288 223 NA NA N N N N RAP1GAP high in NP −3.1 0.03097127 −1.5 13521 139 83 201 32 53 69 N N N N N N LIN7B high in NP −3.4 0.030911615 −1.5 13522 14 34 49 9 9 10 N N P N N N FCH01 high in NP −2.0 0.030864989 −1.5 13523 17 10 16 6 11 6 N N N N N N MYH9 high in NP −1.7 0.030840304 −1.5 13524 3281 2568 4229 2052 2271 1716 N N N N N N SF1 high in NP −2.0 0.030818363 −1.5 13525 1199 1595 1232 648 835 949 N N N N N N PPP1R1A high in NP −2.6 0.030778593 −1.5 13526 46 23 37 14 18 15 N N N N N N ALOXE3 high in NP −2.0 0.030741566 −1.5 13527 78 124 111 44 43 71 N P N N N P CCNE2 high in NP −2.5 0.030668884 −1.5 13528 11 7 4 3 3 3 N N N N N N CABP5 high in NP −4.7 0.030639399 −1.5 13529 22 15 7 9 5 2 P P N N N N ABCC8 high in NP −2.0 0.030618829 −1.5 13530 19 20 41 11 10 7 N P N N N N IPO5 high in NP −2.1 0.030518719 −1.5 13531 388 256 211 115 125 158 N N N N N N TCTN3 high in NP −2.3 0.03050912 −1.5 13532 51 98 68 27 50 25 N N N N N N ARIH2 high in NP −1.8 0.030446037 −1.5 13533 183 255 197 102 134 141 N N N N N N ZNF600 high in NP 4.6 0.030419295 −1.5 13534 9 6 4 1 6 1 N N N N N N APEX1 high in NP −2.2 0.030365812 −1.5 13535 56 20 15 8 9 12 N N N N N N OTUB1 high in NP −3.6 0.03021359 −1.5 13536 116 595 297 107 93 82 N N N N N N RPL27A high in NP −4.3 0.030207419 −1.5 13537 1260 255 368 98 102 234 N N N N N N LOC100131496 high in NP −1.6 0.030151193 −1.5 13538 67 73 54 36 38 45 NA NA N N N N FAM86B2 high in NP −15.4 0.030145022 −1.5 13539 1 31 18 1 1 1 N N N N N N DCAF8 high in NP −2.8 0.030026399 −1.5 13540 150 200 128 31 64 100 NA NA N N N N ANKK1 high in NP −2.5 0.029940688 −1.5 13541 237 218 120 86 89 95 N N N N N N PPP1R8 high in NP −1.9 0.029896119 −1.5 13542 32 60 29 19 22 17 N N N N N N ARGLU1 high in NP −3.1 0.029854978 −1.5 13543 186 113 71 35 36 75 N N N N N N FGL1 high in NP −2.9 0.029789838 −1.5 13544 40 5 5 2 5 2 N N N N N N HIGD2A high in NP −2.7 0.029743212 −1.5 13545 188 110 224 79 62 94 N N N N N N CYBA high in NP −2.2 0.029720584 −1.5 13546 132 214 274 95 114 72 N N N N N N TMED2 high in NP −3.5 0.029710985 −1.5 13547 965 1415 417 347 303 337 N N N N N N NTRK3 high in NP −1.8 0.029533393 −1.5 13548 20 22 24 15 15 18 P P N N N N PAPSS1 high in NP −2.7 0.029359915 −1.5 13549 71 110 39 40 23 25 N N N N N N IL11 high in NP −2.8 0.029320145 −1.5 13550 19 22 39 13 7 13 P P N N N N HS1BP3 high in NP −2.4 0.02927489 −1.5 13551 22 44 19 13 14 6 N N N N N N ADPRHL2 high in NP −2.1 0.029235806 −1.5 13552 32 77 40 19 27 23 N N N N N N STUB1 high in NP −2.7 0.029071928 −1.5 13553 42 171 76 31 29 37 N N N N N N FER1L4 high in NP −2.0 0.029007474 −1.5 13554 21 35 45 16 16 19 N N N N N N BAHCC1 high in NP −2.1 0.028988961 −1.5 13555 34 76 55 33 27 23 N N N N N N TNF high in NP −2.8 0.028959476 −1.5 13556 2902 1444 3897 862 1260 1087 N N N N N N LOC400927 high in NP −2.8 0.028944391 −1.5 13557 9 9 6 3 6 1 N N N N N N SAP130 high in NP −2.5 0.028863481 −1.5 13558 48 66 28 28 18 21 N N N N N N SHCBP1 high in NP −3.7 0.028827825 −1.5 13559 417 698 197 115 131 192 N N N N N N CHMP4B high in NP −1.9 0.028739372 −1.5 13560 527 532 456 214 297 352 N N N N N N ENGASE high in NP −2.4 0.028710573 −1.5 13561 92 193 373 47 79 77 NA NA N N N N AKAP8L high in NP −2.2 0.028690003 −1.5 13562 249 483 423 181 224 187 N N N N N N TRAFD1 high in NP −2.8 0.028651604 −1.5 13563 676 680 319 271 219 224 N N N N N P ARFRP1 high in NP −4.1 0.028639262 −1.5 13564 32 207 85 24 20 33 N N N N N N CFL1 high in NP −2.2 0.02862692 −1.5 13565 7586 8998 7159 3350 5608 2876 N N N N N N TNIP2 high in NP −2.1 0.028613892 −1.5 13566 26 52 30 21 12 15 N N N N N N NCSTN high in NP −2.0 0.028580979 −1.5 13567 45 95 43 30 31 23 N N N N N N VARS2 high in NP −2.7 0.028574808 −1.5 13568 149 352 328 113 136 120 N N N N N N CLDN3 high in NP −2.7 0.02855218 −1.5 13569 4115 1290 2238 865 918 770 N N N N N N FAM108A1 high in NP −3.7 0.028413673 −1.5 13570 204 533 854 163 235 130 N N N N N N PTHLH high in NP 5.2 0.028407501 −1.5 13571 284 1123 956 198 308 34 P P N N N N C7orf63 high in NP −2.3 0.028314248 −1.5 13572 77 65 33 28 21 27 N N N N N N WAPAL high in NP −2.3 0.028279964 −1.5 13573 63 116 82 30 42 57 N N N N N N ORMDL2 high in NP −2.3 0.028264879 −1.5 13574 93 168 183 46 88 49 N N N N N N ZFP57 high in NP −4.2 0.028205911 −1.5 13575 27 50 114 21 17 6 N N N N N N MRPS34 high in NP −2.7 0.028182597 −1.6 13576 68 260 118 68 47 30 N N N N N N OSGEP high in NP −2.6 0.028144885 −1.6 13577 22 34 28 14 5 14 N N N N N N CCDC142 high in NP −2.0 0.028106487 −1.6 13578 46 28 24 17 15 18 N N N N N N LAGE3 high in NP −2.5 0.028048204 −1.6 13579 17 11 6 5 5 5 N N N N N N RPL7L1 high in NP −1.6 0.027885697 −1.6 13580 14 9 8 6 6 6 N N N N N N NWD1 high in NP −4.0 0.027769131 −1.6 13581 20 14 16 6 6 15 N N N N N N OBFC1 high in NP −1.9 0.027699877 −1.6 13582 123 230 115 78 86 62 N N N N N N OASL high in NP −4.4 0.027653936 −1.6 13583 26 12 3 2 2 2 N N N N N N LYPLAL1 high in NP −2.2 0.027647765 −1.6 13584 13 13 7 5 5 5 N N N N N N AQP3 high in NP −3.3 0.02763268 −1.6 13585 95 726 178 47 57 75 N N N N N N GTF2H4 high in NP −3.4 0.027479087 −1.6 13586 63 121 257 30 56 33 N N N N N N C19orf60 high in NP −1.7 0.027392691 −1.6 13587 94 113 191 66 64 56 N N N N N N SLC9A8 high in NP −2.2 0.027386519 −1.6 13588 61 148 97 65 43 34 N N N N N N FLJ45079 high in NP −3.2 0.027348121 −1.6 13589 57 40 30 9 28 11 N P N N N N PPP1R1B high in NP −3.4 0.027314523 −1.6 13590 159 69 122 18 27 65 N N N N N N C14orf179 high in NP −3.7 0.027254183 −1.6 13591 18 9 3 2 2 2 N N N N N N YIPF1 high in NP −2.5 0.027219213 −1.6 13592 15 22 9 7 7 7 N N N N P N KIAA0240 high in NP −1.8 0.027178758 −1.6 13593 46 54 41 32 25 22 N N N N N N RBMX high in NP −2.1 0.02716093 −1.6 13594 15 10 15 9 7 7 N N N N N N KCNH6 high in NP −4.8 0.02715133 −1.6 13595 130 164 64 30 9 61 N N N N N N RBM14 high in NP −2.1 0.027097847 −1.6 13596 70 143 150 51 50 71 N N N N N N C19orf63 high in NP −3.7 0.027041621 −1.6 13597 367 1198 1124 350 300 289 N N N N N N TSPAN4 high in NP −2.4 0.026943568 −1.6 13598 58 73 154 31 31 42 N N N N N N OR7E156P high in NP −2.6 0.026903799 −1.6 13599 12 11 51 4 7 4 N N N N N N GAS2L1 high in NP −2.1 0.026845516 −1.6 13600 75 98 81 43 31 60 N N N N N N CHD2 high in NP −2.3 0.02675912 −1.6 13601 3611 2845 2773 907 1322 2122 N N N N N N PEBP1 high in NP −2.0 0.026747463 −1.6 13602 1170 2263 1162 631 794 620 N N N N N N STCML2 high in NP −2.8 0.026737863 −1.6 13603 163 807 230 91 79 133 N N N N N N ALOX15B high in NP −3.0 0.026584956 −1.6 13604 611 262 484 239 121 169 N N N N N N RPL37 high in NP −4.8 0.026548615 −1.6 13605 7054 1501 1587 338 791 926 N N N N N N SUDS3 high in NP −2.3 0.026532159 −1.6 13606 56 92 42 30 28 25 N N N N N N TTC27 high in NP −1.8 0.026519131 −1.6 13607 47 40 32 19 25 17 N N N N N N PABPC4 high in NP −2.7 0.02647319 −1.6 13608 221 612 268 101 150 163 N N N N N N PSME2 high in NP −2.9 0.026453991 −1.6 13609 135 400 227 58 134 89 N N N N N N KIAA0247 high in NP −2.4 0.026379937 −1.6 13610 492 614 379 229 251 313 N N N N N N C7orf20 high in NP −2.1 0.026237315 −1.6 13611 NA NA NA NA NA NA N N N N N N HBXIP high in NP −2.2 0.026187946 −1.6 13612 495 499 313 153 248 233 N N N N N N TMEM9 high in NP −2.5 0.026137891 −1.6 13613 47 46 25 21 15 7 N N N N N N GPR160 high in NP −3.3 0.026094007 −1.6 13614 11 9 3 2 2 2 N N N N N N PPL high in NP −1.9 0.026080979 −1.6 13615 60 113 66 35 41 40 N N N N N N ZSWIM4 high in NP −2.0 0.025940414 −1.6 13616 80 95 56 29 33 43 N N N N N N CSNK2B high in NP −1.8 0.025927386 −1.6 13617 946 2011 1094 639 632 551 N N N N N N SF4 high in NP −2.8 0.025881445 −1.6 13618 21 45 22 7 15 13 N N N N N N C17orf81 high in NP −1.7 0.025792307 −1.6 13619 35 38 39 19 24 18 N N N N N N EEPD1 high in NP −2.7 0.025732652 −1.6 13620 45 20 34 11 12 20 N N N N N N STX18 high in NP −2.2 0.025683969 −1.6 13621 25 14 14 10 11 14 N N N N N N DNTTIP2 high in NP −1.6 0.025672312 −1.6 13622 147 143 147 86 102 82 N N N N N N MMP24 high in NP −2.9 0.02565517 −1.6 13623 17 22 30 8 8 16 N N N N N N ACSL3 high in NP −2.5 0.025611972 −1.6 13624 167 133 77 35 61 54 N N N N N N CTR9 high in NP −2.5 0.025601001 −1.6 13625 93 149 65 40 42 52 N N N N N N C11orf68 high in NP −3.2 0.02555506 −1.6 13626 611 290 703 116 217 228 N N N N N N SNAPC5 high in NP −1.8 0.025548889 −1.6 13627 10 8 18 5 5 5 N N N N N N UQCRC1 high in NP −1.8 0.025533118 −1.6 13628 718 897 674 530 422 376 N N N N N N DHPS high in NP −2.1 0.025518719 −1.6 13629 59 65 61 17 31 38 N N N N N N CLDND1 high in NP −2.3 0.025427523 −1.6 13630 309 558 335 128 176 241 N N N N P N ZNF408 high in NP −2.9 0.025382268 −1.6 13631 50 95 244 37 33 23 N N N N N N ATAD3B high in NP −3.6 0.02534387 −1.6 13632 51 69 133 19 34 38 N N N N N N ARRB2 high in NP −1.9 0.025286958 −1.6 13633 50 67 111 34 31 32 N N N N N N B3GALT6 high in NP −2.8 0.025232104 −1.6 13634 93 217 193 81 73 63 N N N N N N FANK1 high in NP −2.2 0.025221133 −1.6 13635 18 28 23 11 12 5 N N N N N N B3GALNT2 high in NP −1.9 0.025195762 −1.6 13636 63 165 89 44 47 45 N N N N N N RNF126 high in NP −1.8 0.025106624 −1.6 13637 58 78 108 43 40 34 N N N N N N GJC2 high in NP −2.5 0.025033941 −1.6 13638 15 19 31 9 7 13 N N N N N N CENPT high in NP −2.2 0.025018856 −1.6 13639 602 1020 1139 446 445 463 N N N N N N CEACAM19 high in NP −2.9 0.024979087 −1.6 13640 97 236 352 43 86 83 N N N N N N C1orf126 high in NP −2.3 0.024934517 −1.6 13641 67 89 52 38 33 34 NA NA N N N N TMEM93 high in NP −3.3 0.024928346 −1.6 13642 22 22 17 2 7 13 N N N N N N CD3EAP high in NP −2.1 0.024922175 −1.6 13643 76 131 156 45 65 60 N N N N N N ATG16L2 high in NP −3.5 0.024855664 −1.6 13644 47 76 161 24 14 34 N N N N N N HNRNPAO high in NP −2.6 0.024831665 −1.6 13645 270 606 258 114 151 187 N N N N N N PLAT high in NP −2.3 0.024796009 −1.6 13646 142 390 243 121 110 67 N N N N N N PSMD7 high in NP −2.1 0.024785038 −1.6 13647 173 278 143 96 108 94 N N N N N N SCYL1 high in NP −2.6 0.024763782 −1.6 13648 1119 1027 3637 477 681 475 N N N N N N ZNF32 high in NP −3.0 0.024736355 −1.6 13649 30 72 64 17 16 26 N N N N N N SLC16A5 high in NP −2.6 0.024730184 −1.6 13650 27 62 33 22 15 10 N N N N N N PLK1 high in NP −1.8 0.024683557 −1.6 13651 11 20 11 7 6 6 N N N N N N ZNF117 high in NP −1.9 0.024551906 −1.6 13652 33 32 26 21 16 13 N N N N N N GPR89A high in NP −2.5 0.024466882 −1.6 13653 22 18 6 4 9 5 N N N N N N KLHL17 high in NP −2.6 0.02446071 −1.6 13654 39 38 101 18 12 23 N N N N N N RPS15A high in NP −3.6 0.024412713 −1.6 13655 4216 1142 1767 332 758 751 N N N N N N GGT7 high in NP −2.8 0.024285861 −1.6 13656 90 150 183 34 62 72 N N N N N N SENP3 high in NP −2.1 0.024228264 −1.6 13657 45 74 95 32 34 40 N N N N N N SEC14L2 high in NP −2.1 0.024200837 −1.6 13658 315 434 370 226 209 88 N N N N N N LOC93622 high in NP −2.6 0.024157639 −1.6 13659 21 61 51 20 13 11 NA NA N N N N PUF60 high in NP −3.1 0.024140496 −1.6 13660 222 557 529 134 201 189 N N N N N N FAM108C1 high in NP −2.1 0.023846338 −1.6 13661 38 77 42 27 27 20 N N N N N N CHRNB1 high in NP −2.0 0.023788741 −1.6 13662 30 40 40 20 11 18 N N N N N N TPD52 high in NP −2.5 0.023721544 −1.6 13663 283 143 100 67 54 55 N N N N N N TESK2 high in NP −2.1 0.023660518 −1.6 13664 45 21 19 12 9 9 N N N N N N DCUN1D2 high in NP −2.2 0.023635834 −1.6 13665 42 45 88 24 28 20 N N N N N N DHRS13 high in NP −2.3 0.023629663 −1.6 13666 104 47 53 24 29 22 N N N N N N PKIA high in NP −5.5 0.023580293 −1.6 13667 18 14 2 2 2 2 N P N N N N C1orf170 high in NP −2.1 0.023570694 −1.6 13668 7 4 5 4 2 2 NA NA N N N N PIK3R2 high in NP −3.1 0.023558352 −1.6 13669 52 140 27 13 23 21 N N N N P N LUC7L2 high in NP −3.7 0.023528867 −1.6 13670 67 203 174 44 63 52 N N N N N N PPIH high in NP −2.5 0.023510354 −1.6 13671 24 8 6 4 4 4 N N N N N N NKIRAS2 high in NP −2.1 0.023500754 −1.6 13672 102 180 92 72 48 57 N N N N N N SLC39A6 high in NP −2.3 0.023417101 −1.6 13673 116 261 126 62 63 83 N N N N N N MRPL45 high in NP −1.8 0.023398587 −1.6 13674 221 308 245 142 177 132 N N N N N N GPLD1 high in NP −2.3 0.02335059 −1.6 13675 16 28 15 12 8 8 N N N N N N ARL4D high in NP −1.8 0.023263508 −1.6 13676 15 21 10 7 8 6 N N N N N N SLC37A3 high in NP −2.5 0.023237452 −1.6 13677 139 191 92 40 38 85 N N N N N N BMP3 high in NP −2.2 0.023218939 −1.6 13678 41 29 19 15 8 12 N P N N N N ARL4A high in NP −3.0 0.023171626 −1.6 13679 55 27 43 24 18 21 N N N N N N RFC2 high in NP −2.1 0.023140771 −1.6 13680 11 17 8 6 6 6 N N N N N N TMEM30A high in NP −1.9 0.023067403 −1.6 13681 374 701 447 261 257 307 N N N N N N FAM36A high in NP −2.3 0.023020776 −1.6 13682 131 110 70 48 41 41 N N N N N P SNORD10 high in NP −5.5 0.022974835 −1.6 13683 48 9 17 5 1 9 N N N N N N FXN high in NP −1.9 0.02295975 −1.6 13684 118 119 134 68 72 53 N N N N N N KRI high in NP −2.3 0.022946037 −1.6 13685 25 37 16 9 14 9 N N N N N N SMTN high in NP −3.8 0.022930952 −1.6 13686 1357 592 1975 236 336 562 N N N N N N FLJ35220 high in NP −2.2 0.022917924 −1.6 13687 17 49 33 9 9 17 N N N N N N MRPS24 high in NP −1.9 0.022897353 −1.6 13688 742 1195 891 467 463 590 N N N N N N PRSS22 high in NP −2.8 0.022887754 −1.6 13689 556 1047 1400 276 415 525 N N N N N N PDGFB high in NP −1.9 0.022881583 −1.6 13690 26 28 28 12 19 13 N N N N N N CCNDBP1 high in NP −1.9 0.022875411 −1.6 13691 26 29 17 14 14 15 N N N N N N ATP5D high in NP −2.3 0.022806843 −1.6 13692 676 1158 1153 566 528 318 N N N N N N BTBD1 high in NP −2.3 0.022791072 −1.6 13693 42 88 51 24 36 19 N N N N N N CIB1 high in NP −490.3 0.022732789 −1.6 13694 8 1577 2030 8 8 8 N N N N N N DUSP19 high in NP −2.0 0.022726618 −1.6 13695 328 395 329 187 157 239 N N N N N N PSMC4 high in NP −2.5 0.022669021 −1.6 13696 110 292 100 45 70 57 N N N N N N RARA high in NP −2.3 0.022644336 −1.6 13697 746 457 773 241 322 406 N N N N N N LMNA high in NP −3.0 0.022638165 −1.6 13698 11730 10406 10785 3647 3091 7906 N N N N N N SFRS9 high in NP −1.8 0.022616223 −1.6 13699 179 299 171 98 109 114 N N N N N N LPHN3 high in NP −1.7 0.022610052 −1.6 13700 13 24 14 8 8 8 N N N N N N MKI67IP high in NP −3.2 0.022540112 −1.6 13701 49 116 119 20 45 29 N N N N N N ABCE1 high in NP −2.9 0.022525027 −1.6 13702 105 208 89 33 61 54 N N N N N N TULP3 high in NP −1.9 0.02242766 −1.6 13703 134 162 127 46 79 78 N N N N N N LPCAT3 high in NP 4.8 0.022398176 −1.6 13704 112 376 394 101 83 74 N N N N N N EPCAM high in NP −2.9 0.022350178 −1.7 13705 147 85 111 25 56 54 NA NA N N N N RPL26L1 high in NP −2.2 0.022309723 −1.7 13706 59 75 63 22 44 31 N N N N N N PRCP high in NP −3.0 0.022279553 −1.7 13707 19 52 34 18 13 10 N N N N N N PDRG1 high in NP −2.2 0.022267211 −1.7 13708 59 70 65 20 31 41 P P N N N N ITPR2 high in NP −2.2 0.022223327 −1.7 13709 186 269 220 159 95 99 N N N N N N CTTN high in NP −2.7 0.022110189 −1.7 13710 716 1707 1306 511 489 606 N N N N N N ZNF585A high in NP −1.8 0.022072477 −1.7 13711 9 13 9 6 4 4 N N N N N N MAP1LC3B high in NP −2.1 0.022017622 −1.7 13712 646 336 346 228 183 179 N N N N N N FLJ36031 high in NP −2.0 0.021946997 −1.7 13713 22 32 19 9 12 14 N N N N N N ANXA4 high in NP −1.8 0.021927112 −1.7 13714 93 167 83 51 57 54 N N N N N N FANCL high in NP −2.2 0.021908598 −1.7 13715 7 10 6 2 5 2 N N N N N N C20orf54 high in NP −2.5 0.021902427 −1.7 13716 13 38 29 5 10 11 N N N N N N P2RX4 high in NP −3.3 0.021859229 −1.7 13717 241 220 522 67 122 142 N N N N N N MFGE8 high in NP −3.0 0.021853058 −1.7 13718 4419 2442 11624 982 1616 1964 N N N N N N PTP4A2 high in NP −4.1 0.021818088 −1.7 13719 345 709 178 108 100 155 N N N N N N DUSP15 high in NP −2.3 0.021775576 −1.7 13720 7 11 6 2 2 6 N N N N N N FOXH1 high in NP −2.0 0.021760491 −1.7 13721 9 11 21 4 4 4 N N N N N N USP7 high in NP −2.5 0.021715922 −1.7 13722 394 892 798 208 272 407 N N N N N N FAM40A high in NP −3.3 0.02170975 −1.7 13723 43 77 33 11 26 22 N N N N N N EXOC7 high in NP −2.9 0.021678895 −1.7 13724 272 499 867 201 251 158 N N N N N N ELF3 high in NP −3.0 0.021634325 −1.7 13725 1303 1051 622 331 365 521 N N N N N N SLC39A4 high in NP −3.3 0.021509531 −1.7 13726 55 65 103 17 34 34 N N N N N N TTC33 high in NP −1.8 0.02150336 −1.7 13727 14 18 12 9 9 9 N N N N N N REST high in NP −2.9 0.021476618 −1.7 13728 22 59 22 16 10 13 N N N N N N LRRK1 high in NP −1.9 0.021446448 −1.7 13729 50 62 59 18 29 32 N N N N N N FAM129B high in NP −2.0 0.021395022 −1.7 13730 392 406 723 237 333 214 N N N N N N PPP1R15A high in NP −3.0 0.021344967 −1.7 13731 376 258 288 75 116 198 N N N N N N MPG high in NP −2.5 0.021338796 −1.7 13732 216 373 543 150 174 125 N N N N N N FAM83A high in NP −1.8 0.021332625 −1.7 13733 10 22 10 5 5 5 N N N N N N SAPS2 high in NP −2.1 0.021326454 −1.7 13734 144 192 288 82 108 107 N N N N N N PRKCZ high in NP −3.0 0.021303826 −1.7 13735 73 143 194 47 62 43 N N N N N N C1orf152 high in NP −1.9 0.021297655 −1.7 13736 8 7 15 3 3 3 N N N N N N RNF149 high in NP −2.0 0.021246914 −1.7 13737 261 192 168 88 98 118 N N N N N N SERPINA1 high in NP −6.7 0.021131034 −1.7 13738 397 389 74 42 72 31 N N N N N N CCDC85C high in NP −2.3 0.021104292 −1.7 13739 198 238 190 42 104 121 NA NA N N N N MYBBP1A high in NP −2.4 0.02105218 −1.7 13740 93 262 166 51 75 77 N N N N N N C18or26 high in NP −2.3 0.021035038 −1.7 13741 20 28 16 13 8 10 N N N N N N C14orf1 high in NP −3.2 0.020893102 −1.7 13742 16 34 12 10 7 4 N N N N N N VCP high in NP −2.1 0.020877331 −1.7 13743 336 494 600 289 256 196 N N N N N N GINS2 high in NP −2.1 0.020854704 −1.7 13744 9 9 10 4 4 7 N N N N N N FAM192A high in NP −2.0 0.020747737 −1.7 13745 39 36 26 14 15 18 NA NA N N N N RPL17 high in NP −2.2 0.020716196 −1.7 13746 18736 32515 26257 12765 12776 15180 N N N N N N NDUFV2 high in NP −2.4 0.020703854 −1.7 13747 227 674 189 104 104 112 N N N N N N GSTP1 high in NP −2.5 0.020646942 −1.7 13748 1062 3853 1765 726 753 576 P N N N N N CD14 high in NP −5.7 0.0206298 −1.7 13749 131 477 627 92 58 121 N N N N N N ZBTB47 high in NP −2.6 0.020550261 −1.7 13750 31 93 65 27 28 18 N N N N N N PIP high in NP −2.7 0.020544089 −1.7 13751 23 5 3 2 2 2 N N N N N N BEND2 high in NP −2.6 0.020505005 −1.7 13752 44 51 93 28 26 20 N N N N N N C22orf28 high in NP −2.8 0.020484435 −1.7 13753 182 100 59 27 44 31 P N N N N N MIA high in NP −3.1 0.020472093 −1.7 13754 118 117 184 26 70 59 N N N N N N ZNF777 high in NP −3.6 0.020461122 −1.7 13755 31 88 92 15 25 25 N N N N N N THOC4 high in NP −2.2 0.020454951 −1.7 13756 22 22 22 10 17 10 N N N N N N ZW10 high in NP −2.9 0.020417924 −1.7 13757 26 76 57 16 14 22 N N N N N N C1orf86 high in NP −2.6 0.020411753 −1.7 13758 128 183 209 47 103 66 N N N N N N CYFIP2 high in NP −3.0 0.020321242 −1.7 13759 29 14 10 6 8 6 N N N N N N MAP1B high in NP −2.8 0.020289015 −1.7 13760 351 712 390 268 261 157 N N N N N N VEGFB high in NP −2.5 0.020243075 −1.7 13761 99 92 58 43 18 38 N N N N N N BTBD19 high in NP −5.3 0.020230732 −1.7 13762 11 11 7 2 2 8 NA NA N N N N MND1 high in NP −3.0 0.02016285 −1.7 13763 6 2 2 3 1 1 N N N N N N ZNF138 high in NP −1.8 0.020142965 −1.7 13764 12 6 6 4 4 4 N N N N N N TMX1 high in NP −2.0 0.020126509 −1.7 13765 42 93 37 23 20 23 NA NA N N N N TIA1 high in NP −1.7 0.020079882 −1.7 13766 30 43 35 16 22 17 N N N N N N CSNK1G2 high in NP −2.3 0.020044912 −1.7 13767 92 122 105 49 45 70 N N N N N N PSMD2 high in NP −2.4 0.019985943 −1.7 13768 384 825 653 321 296 262 N N N N N N NAA25 high in NP −2.3 0.019979772 −1.7 13769 346 233 243 113 143 155 NA NA N N N N TFEB high in NP −2.0 0.019939317 −1.7 13770 30 41 39 22 24 26 N N N N N N UBA1 high in NP −2.2 0.01991189 −1.7 13771 598 484 791 314 287 375 P N N N N N STX3 high in NP −3.4 0.019895433 −1.7 13772 226 188 98 59 62 77 N N N N N N RPL7 high in NP −3.7 0.019882405 −1.7 13773 3008 1081 756 232 417 524 N N N N N N RRBP1 high in NP −3.1 0.019795324 −1.7 13774 163 305 101 59 66 57 N N N N N N ATP1B1 high in NP −3.8 0.019763782 −1.7 13775 430 426 176 142 117 101 N N N N N N CDK5RAP2 high in NP −2.5 0.019757611 −1.7 13776 83 89 136 52 33 48 N N N N N N SNRPB high in NP −2.3 0.019742526 −1.7 13777 2153 4645 2298 1028 1113 1430 N N N N N N HMG20B high in NP −2.3 0.019736355 −1.7 13778 320 333 282 153 112 204 N N N N N N LMX1B high in NP −2.1 0.019656816 −1.7 13779 59 101 87 44 48 26 N N N N N N ANOS high in NP −3.2 0.019647216 −1.7 13780 45 156 143 27 26 43 N N N N N N ENO1 high in NP −2.2 0.019455S11 −1.7 13781 1523 2303 1550 961 1030 704 N N N N N N SNRNP200 high in NP −2.2 0.019421626 −1.7 13782 305 252 249 107 126 177 N N N N N N COMMD6 high in NP −2.4 0.019398313 −1.7 13783 1043 519 565 215 277 349 N N N N N N GLI4 high in NP −3.2 0.019392142 −1.7 13784 29 18 35 4 11 13 N N N N N N STX5 high in NP −3.0 0.019385971 −1.7 13785 1171 722 1696 442 432 505 N N N N N N PSMA2 high in NP −3.4 0.019345516 −1.7 13786 196 153 71 28 59 42 N N N N N N IRS1 high in NP −2.0 0.019324259 −1.7 13787 64 61 65 32 30 28 N N N N N N DUSP16 high in NP −3.6 0.019318088 −1.7 13788 39 21 11 10 4 4 N N N N N N ETNK2 high in NP −2.9 0.019297518 −1.7 13789 158 54 33 20 21 19 N N N N N N DYNLRB1 high in NP −5.1 0.019275576 −1.7 13790 57 324 155 35 38 46 N N N N N N TXNDC11 high in NP −3.1 0.019085642 −1.7 13791 51 53 21 19 12 13 N N N N N N C12orf57 high in NP −1.8 0.019067128 −1.7 13792 1991 1687 1757 1016 967 1158 N N N N N N NDUFB3 high in NP −2.9 0.019046558 −1.7 13793 7 8 11 2 5 2 N N N N N N ECH1 high in NP −2.2 0.01903353 −1.7 13794 102 91 68 32 42 50 N N N N N N FAM160A2 high in NP −5.8 0.019010902 −1.7 13795 37 178 187 20 29 34 N N N N N N HSD11B1L high in NP −2.1 0.018996503 −1.7 13796 54 47 70 29 22 27 N N N N N N ARSJ high in NP −2.2 0.018951248 −1.7 13797 44 67 78 25 32 34 N N N N N N RIF1 high in NP −2.2 0.01886828 −1.7 13798 61 111 57 31 39 34 N N N N N N SLC17A5 high in NP −2.3 0.01882234 −1.7 13799 35 74 28 17 19 17 N N N N N N PPEF2 high in NP −2.2 0.018816168 −1.7 13800 24 16 23 10 11 15 N N N N N N CDT1 high in NP −2.2 0.01880314 −1.7 13801 16 12 17 6 6 6 N N N N N P DOPEY2 high in NP −2.5 0.01878257 −1.7 13802 203 387 141 74 100 92 N N N N N N LOC374491 high in NP −3.4 0.018776399 −1.7 13803 35 10 7 6 4 4 N N N N N N MPHOSPH8 high in NP −2.4 0.018754457 −1.7 13804 124 223 239 103 75 102 N N N N N N RPL27 high in NP −2.8 0.018699602 −1.7 13805 911 894 426 224 240 379 N N N N N N RTN2 high in NP −6.5 0.01866189 −1.7 13806 22 71 198 10 17 8 N N N N P N TP53 high in NP −2.3 0.018572751 −1.7 13807 51 131 53 26 31 31 N N N N N N SLA2 high in NP −3.0 0.018557666 −1.7 13808 9 9 6 4 4 7 N N N N N N INO80B high in NP −2.9 0.018525439 −1.7 13809 105 50 110 18 41 29 N N N N N N HNRNPUL1 high in NP −2.9 0.018513097 −1.7 13810 149 156 77 42 63 45 N N N N P N KIAA0427 high in NP −3.3 0.018467841 −1.7 13811 181 398 558 130 159 144 N N N N N N LIPH high in NP −3.2 0.018438357 −1.7 13812 26 22 20 5 15 5 N N N N N N RBMXL1 high in NP −1.7 0.018391045 −1.7 13813 20 18 14 8 8 8 NA NA N N N N PHF23 high in NP −2.9 0.018375274 −1.7 13814 51 89 72 20 23 44 N N N N N N ICA1 high in NP −2.7 0.018365675 −1.7 13815 429 482 911 216 324 175 N N N N N N CUEDC1 high in NP −3.0 0.018349904 −1.7 13816 22 59 17 6 12 6 N N N N N N ALDH2 high in NP −1.7 0.018334819 −1.7 13817 183 170 178 95 115 99 N N N N N N GART high in NP −2.0 0.018276536 −1.7 13818 58 85 90 32 49 34 N N N N N N IER2 high in NP −2.0 0.018225795 −1.7 13819 4591 4675 7169 2562 2260 3110 N N N N N N MRPL42 high in NP −2.9 0.018212767 −1.7 13820 257 337 150 120 97 91 N N N N N N DYNC1LI2 high in NP −2.4 0.018203168 −1.7 13821 994 1233 783 560 445 504 N N N N N N PABPC1L high in NP −3.7 0.018162713 −1.7 13822 128 77 79 21 40 44 N N N N N N DTWD1 high in NP −2.2 0.018103058 −1.7 13823 15 21 12 7 7 10 N N N N N N SALL2 high in NP −4.0 0.018057117 −1.7 13824 10 15 14 8 8 6 P P N N N N ZBTB8A high in NP −2.3 0.018050946 −1.7 13825 1070 725 755 282 359 520 NA NA N N N N CLPP high in NP −3.4 0.018037918 −1.7 13826 42 113 159 31 26 34 N N N N N N ALKBH5 high in NP −2.6 0.018002948 −1.7 13827 132 177 91 44 48 78 N N N N N N YBX1 high in NP −4.7 0.017986492 −1.7 13828 93 247 102 12 64 39 N N N N N N HPCAL1 high in NP −3.0 0.017915867 −1.7 13829 1424 853 1808 521 617 471 N N N N N N LOC100294362 high in NP −2.6 0.017861698 −1.7 13830 451 349 441 186 134 245 NA NA N N N N DYNC2LI1 high in NP −3.4 0.017841127 −1.7 13831 21 21 15 12 5 8 N N N N N N MKRN2 high in NP −3.1 0.017828785 −1.7 13832 30 80 46 14 17 27 N N N N N N ARHGAP30 high in NP −2.1 0.017793815 −1.7 13833 94 78 60 28 45 32 N N N N N N GRASP high in NP −3.3 0.017736903 −1.8 13834 31 50 102 21 19 10 N N N N N N MCAT high in NP −2.8 0.017714962 −1.8 13835 87 170 225 74 57 48 N N N N N N RPS15 high in NP −3.7 0.017679992 −1.8 13836 166 78 183 42 57 45 N N N N N N PYGB high in NP −2.2 0.017550398 −1.8 13837 595 603 416 272 282 293 N N N N N N FKBP11 high in NP −3.1 0.017499657 −1.8 13838 334 707 818 266 248 260 N N N N N N SFPQ high in NP −2.8 0.017486629 −1.8 13839 263 837 464 132 182 205 N N N N N P PICK1 high in NP −2.2 0.017429717 −1.8 13840 240 233 441 102 120 144 N N N N N N ZBTB48 high in NP −3.6 0.017400233 −1.8 13841 45 152 112 25 32 35 N N N N N N ORMDL1 high in NP −2.7 0.017385148 −1.8 13842 83 89 43 25 32 27 N N N N N N C14orf101 high in NP −1.7 0.017378977 −1.8 13843 20 26 26 14 12 15 N N N N N N LRRC4 high in NP −1.7 0.017358406 −1.8 13844 53 71 57 30 35 34 N N N N P N SPEN high in NP −2.9 0.017323437 −1.8 13845 488 585 476 196 242 352 N N N N N N DGCR2 high in NP −3.0 0.017296009 −1.8 13846 84 250 171 66 73 49 N N N N N N FAM3D high in NP −7.9 0.017271325 −1.8 13847 13 19 8 1 1 9 N N N N N N XRN2 high in NP −4.1 0.017265154 −1.8 13848 214 285 101 63 80 61 N N N N N N DECR1 high in NP −2.4 0.017258982 −1.8 13849 115 143 82 66 53 35 N N N N N N ENTPD4 high in NP −2.5 0.017230184 −1.8 13850 21 33 18 12 14 8 N N N N N N PHGR1 high in NP −10.3 0.017167101 −1.8 13851 274 47 330 31 33 16 NA NA N N N N GPR108 high in NP −3.1 0.01716093 −1.8 13852 200 420 497 149 162 132 N N N N N N CASP6 high in NP −2.1 0.017154759 −1.8 13853 28 37 32 17 18 11 N N N N N N RRP7A high in NP −8.9 0.017148587 −1.8 13854 22 25 11 2 2 13 N N N N N N SPAG16 high in NP −2.2 0.017137617 −1.8 13855 119 80 88 48 43 35 N N N N N N CHCHD2 high in NP −2.8 0.01707042 −1.8 13856 3382 5073 11130 1730 2347 1631 N N N N N N DMAP1 high in NP −3.2 0.017023793 −1.8 13857 135 200 331 109 61 57 N N N N N N NAA50 high in NP −2.0 0.016986081 −1.8 13858 86 120 98 50 51 65 NA NA N N N N SDHAP1 high in NP −1.6 0.016967567 −1.8 13859 9 7 6 4 4 4 NA NA N N N N RPS20 high in NP −6.7 0.016961396 −1.8 13860 2154 3077 556 267 373 494 N N N N N N FBP1 high in NP −2.6 0.016945625 −1.8 13861 132 115 86 63 40 26 N N N N N N LRRC41 high in NP −8.0 0.01691477 −1.8 13862 130 1186 516 63 84 116 N N N N N N TIMM44 high in NP −1.8 0.01680506 −1.8 13863 355 428 424 199 237 257 N N N N N N LOC728640 high in NP −5.1 0.016798889 −1.8 13864 43 45 12 3 8 14 NA NA N N N N ERCC2 high in NP −3.1 0.01677489 −1.8 13865 47 28 47 16 9 9 N N N N N N PGR high in NP −1.8 0.016629526 −1.8 13866 31 44 42 27 23 26 N N N N N N CHAD high in NP −2.9 0.016623354 −1.8 13867 69 17 15 5 6 3 N N N N N N ZNF12 high in NP −2.7 0.016613755 −1.8 13868 87 105 61 33 30 52 N P N N N N ELF2 high in NP −2.7 0.016547244 −1.8 13869 50 82 37 16 13 29 N N N N N N FAM102A high in NP −2.6 0.016527359 −1.8 13870 1589 3416 1192 798 560 706 N N N N N N CBY1 high in NP −2.6 0.016515016 −1.8 13871 99 202 141 73 57 56 N N N N N N PITPNM1 high in NP −1.8 0.016504046 −1.8 13872 92 101 108 52 56 62 N N N N N N RING1 high in NP −2.5 0.016469076 −1.8 13873 1050 780 697 297 440 431 N N N N N N UBE2R2 high in NP −2.0 0.016417649 −1.8 13874 2313 1818 1756 912 991 1191 N N N N N N RUNX1 high in NP −2.1 0.01637788 −1.8 13875 1630 1478 1997 983 995 1265 N N P N N N ACAD8 high in NP −3.4 0.016371709 −1.8 13876 55 72 25 14 19 16 N N N N N N ING5 high in NP −2.4 0.016345653 −1.8 13877 56 71 69 21 41 25 N N N N N N NME7 high in NP −3.4 0.016339482 −1.8 13878 147 120 50 26 42 34 N N N N N N NOB1 high in NP −2.2 0.01633331 −1.8 13879 41 50 64 27 29 22 N N N N N N ABCB9 high in NP −2.3 0.016203716 −1.8 13880 32 31 19 13 11 11 N N N N N N PRMT5 high in NP −2.5 0.016152976 −1.8 13881 32 71 45 15 29 18 N N N N N N GFOD2 high in NP −1.9 0.016127606 −1.8 13882 268 313 372 179 177 203 N N N N N N TMX2 high in NP −2.8 0.016090579 −1.8 13883 60 167 44 26 27 16 NA NA N N N N METTL12 high in NP −2.4 0.016064523 −1.8 13884 27 14 19 9 8 11 NA NA N N N N HDAC11 high in NP −2.5 0.016058352 −1.8 13885 35 39 32 23 13 14 N N N N N N MAPKBP1 high in NP −3.1 0.01605218 −1.8 13886 267 150 332 66 73 125 N N N N N N TIMM50 high in NP −2.4 0.016009668 −1.8 13887 162 402 162 76 100 73 N N N N N N AGR2 high in NP −3.6 0.01599664 −1.8 13888 21 160 26 5 10 5 N N N N N N NKRF high in NP −2.3 0.015965784 −1.8 13889 38 46 29 22 13 19 N N N N P N COQ4 high in NP −2.2 0.015947271 −1.8 13890 321 501 526 171 240 226 N N N N N N GLIPR1 high in NP −2.3 0.015926015 −1.8 13891 1023 934 1112 321 516 589 N N N N N N RPS18 high in NP −3.1 0.01584579 −1.8 13892 9710 9856 5270 1741 3155 3905 N N N N N N NOP14 high in NP −2.7 0.015779964 −1.8 13893 79 114 126 24 42 59 N N N N N N AIMP1 high in NP −2.3 0.015696311 −1.8 13894 171 241 161 56 87 102 NA NA N N N N AP2A1 high in NP −2.7 0.01569014 −1.8 13895 22 55 45 20 16 17 N N N N N N PPIA high in NP −2.4 0.015648313 −1.8 13896 405 282 236 157 115 124 N N N N N N PLD2 high in NP −2.1 0.015635971 −1.8 13897 82 112 127 51 37 59 N N N N N N HNRNPUL2 high in NP −2.7 0.015601687 −1.8 13898 26 55 49 19 20 15 N N N N N N GLT25D1 high in NP −2.6 0.015586602 −1.8 13899 80 276 109 38 41 52 N N N N N N DDR1 high in NP −2.4 0.015543404 −1.8 13900 1958 4923 1938 859 922 1162 N N N N N N STBD1 high in NP −2.5 0.01549472 −1.8 13901 60 87 84 22 29 46 N N N N N N CDC37 high in NP −1.9 0.01540901 −1.8 13902 1616 2114 2014 822 1093 1156 P N N N N N VAMP8 high in NP −2.8 0.015367869 −1.8 13903 407 1480 350 159 163 181 N N N N N N PEX14 high in NP −2.2 0.015330156 −1.8 13904 45 56 42 18 28 21 N N N N N N TFE3 high in NP −1.9 0.015323985 −1.8 13905 110 116 149 58 69 70 N N N N N N FGF13 high in NP −2.4 0.015317814 −1.8 13906 27 18 20 8 13 9 P P N N N N SNORD36A high in NP 5.3 0.01528353 −1.8 13907 9 11 8 1 1 7 N N N N N N NUP88 high in NP −3.7 0.015159421 −1.8 13908 193 194 78 48 61 52 N N N N N N C21orf49 high in NP −2.1 0.015126509 −1.8 13909 108 96 109 57 61 42 NA NA N N N N STK10 high in NP −2.4 0.015080568 −1.8 13910 54 172 97 33 41 39 N N N N N N RCVRN high in NP −2.9 0.015062054 −1.8 13911 10 16 14 5 8 5 P P N N N N ARRDC2 high in NP −3.3 0.014957145 −1.8 13912 80 161 82 22 39 48 N N N N N N HSPB8 high in NP −3.4 0.014892005 −1.8 13913 57 155 151 38 31 54 N N N N N N ILVBL high in NP −2.6 0.014862521 −1.8 13914 84 45 46 15 26 16 N N N N N N LGALS8 high in NP −2.1 0.014721956 −1.8 13915 115 100 113 54 57 50 N N N N P N DALRD3 high in NP −2.4 0.014693157 −1.8 13916 264 475 235 133 125 146 N N N N N N EEF1D high in NP −2.6 0.014633502 −1.8 13917 2745 6312 6667 1183 1490 2313 N N N N N N SLC38A10 high in NP −2.2 0.014612246 −1.8 13918 80 147 100 66 47 44 N N N N N N POLR2G high in NP −2.9 0.014589619 −1.8 13919 146 228 90 70 59 45 N N N N N N ATAD1 high in NP −2.2 0.014512137 −1.8 13920 147 113 81 42 50 45 N N N N N N CPLX1 high in NP −4.2 0.014466196 −1.8 13921 187 96 218 49 63 19 P P N N N N CCNG1 high in NP −4.2 0.014456596 −1.8 13922 95 79 27 16 14 21 N N N N N N P4HB high in NP −3.1 0.014422998 −1.8 13923 2979 4808 1866 1478 1091 760 N N N N N N MIB2 high in NP −3.2 0.014393513 −1.8 13924 287 211 842 111 93 106 N N N N N N CDC42BPB high in NP −3.3 0.0143654 −1.8 13925 171 458 292 87 99 160 N N N N N N RECQL5 high in NP −2.6 0.014350315 −1.8 13926 651 647 389 253 241 277 N N N P N N HDAC2 high in NP −2.3 0.014340716 −1.8 13927 133 111 126 46 59 67 N N N N N N KCNMA1 high in NP −2.0 0.014313974 −1.8 13928 125 174 173 89 95 57 N P N N N N RBM12 high in NP −2.8 0.014307803 −1.8 13929 215 300 186 49 116 102 N N N N N N GYLTL1B high in NP −3.4 0.014298204 −1.8 13930 26 19 44 9 9 13 N N N N N N LMF2 high in NP −4.3 0.014191237 −1.8 13931 162 492 471 94 99 121 N N N N N N CHKB high in NP −3.3 0.014185066 −1.8 13932 83 140 98 19 33 59 N N N N N N DYRK3 high in NP −2.1 0.014178895 −1.8 13933 15 11 10 9 7 7 N N N N N N EPB41L5 high in NP −2.1 0.014162438 −1.8 13934 21 46 32 16 16 16 N N N N N N CAD high in NP −2.8 0.014156267 −1.8 13935 134 157 475 71 59 53 N N N N N N IGFBP2 high in NP −4.0 0.014117183 −1.9 13936 74 125 85 31 25 59 N N N N N N IL13RA1 high in NP −5.2 0.014101413 −1.9 13937 111 527 348 84 85 57 N N N N N N EHBP1L1 high in NP −2.2 0.014030787 −1.9 13938 82 152 147 67 55 51 N N N N N N ALDH4A1 high in NP −3.2 0.013997189 −1.9 13939 88 109 323 40 49 28 N N N N N N GRK6 high in NP −2.4 0.013975247 −1.9 13940 134 204 324 77 83 87 N N N N N N CBX6 high in NP −2.7 0.013965647 −1.9 13941 37 51 37 15 27 11 N N N N N N PRAGMIN high in NP −2.2 0.013887479 −1.9 13942 NA NA NA NA NA NA N N N N N N NCAPH2 high in NP −2.9 0.013874451 −1.9 13943 314 297 465 71 123 187 N N N N N N TTRAP high in NP −3.4 0.01386828 −1.9 13944 22 24 14 12 6 10 N N N N N N TOLLIP high in NP −2.1 0.01380794 −1.9 13945 198 376 295 120 154 147 N N N N N N CTDSP1 high in NP −5.0 0.013728401 −1.9 13946 155 804 331 118 78 72 N N N N N N RPL29 high in NP −2.8 0.013716059 −1.9 13947 188 81 116 41 43 36 N N N N N N MAPK8IP1 high in NP −2.3 0.01363172 −1.9 13948 19 9 6 3 3 3 N N N N N N DHX29 high in NP −2.0 0.013558352 −1.9 13949 34 40 27 18 13 19 N N N N N N C7orf53 high in NP −2.7 0.013548752 −1.9 13950 39 26 22 8 8 14 N N N N N N Clorf77 high in NP −5.0 0.013526125 −1.9 13951 85 86 25 11 5 23 N N N N N N CFDP1 high in NP −3.7 0.013481555 −1.9 13952 47 41 50 10 12 28 N N N N N N RPSAP58 high in NP −3.2 0.013468527 −1.9 13953 6862 4967 3444 738 1582 2047 NA NA N N N N ZDHHC4 high in NP −3.7 0.013448642 −1.9 13954 192 104 88 28 61 20 N N N N N N IFRD2 high in NP −7.4 0.013442471 −1.9 13955 95 439 480 36 75 70 N N N N N N IMPS high in NP −2.9 0.01338076 −1.9 13956 66 175 61 36 35 26 N N N N N N CD1D high in NP −1.8 0.013362246 −1.9 13957 9 9 6 4 4 4 P P N N N N SCAMP4 high in NP −1.9 0.013343047 −1.9 13958 70 107 81 46 44 37 N N N N N N ARAF high in NP −5.4 0.013331391 −1.9 13959 40 201 110 20 38 13 N N N N N N MC1R high in NP −3.8 0.013295049 −1.9 13960 21 71 40 11 12 17 N N N N N N TCEB2 high in NP −2.1 0.013276536 −1.9 13961 188 250 379 123 102 116 N N N N N N STRC high in NP −2.6 0.013233338 −1.9 13962 23 22 13 7 7 10 N N N N N N TOP1MT high in NP −4.4 0.013227167 −1.9 13963 23 22 6 5 5 2 N N N N N N ADRM1 high in NP −3.8 0.013181226 −1.9 13964 358 1024 804 248 296 223 N N N N N N PROCA1 high in NP −3.0 0.013063289 −1.9 13965 8 5 7 5 3 3 N N N N N N SPTAN1 high in NP −2.5 0.013006377 −1.9 13966 146 193 184 80 61 105 N N N N N N THAP9 high in NP −2.1 0.012974835 −1.9 13967 14 15 11 8 8 6 N N N N N N HCFC1 high in NP −3.2 0.012962493 −1.9 13968 179 523 353 123 107 143 N N N N N N WDR18 high in NP −2.6 0.012942608 −1.9 13969 69 142 136 46 54 28 N N N N N N NFKBIL1 high in NP −2.8 0.012931637 −1.9 13970 56 55 70 22 22 35 N N N N N N GAK high in NP −2.4 0.012916552 −1.9 13971 972 1302 1555 458 679 573 N N N N N N TMEM51 high in NP −3.0 0.012901467 −1.9 13972 173 220 108 63 40 75 N N N N N N TRPM4 high in NP −1.7 0.01288364 −1.9 13973 34 52 46 23 21 22 N N N N N N NAT14 high in NP −4.5 0.012868555 −1.9 13974 37 56 103 19 20 7 N N N N N N NQ01 high in NP −1.9 0.012825357 −1.9 13975 61 85 59 37 43 30 N N N N N N PLA2G2A high in NP −2.6 0.012782159 −1.9 13976 12 12 6 6 4 4 N P N N N N SLC35A4 high in NP −5.3 0.012767074 −1.9 13977 74 390 193 57 42 38 N N N N N N CD2AP high in NP −3.4 0.012750617 −1.9 13978 107 85 47 34 27 28 N N N N N N SIGLEC8 high in NP −2.9 0.012738275 −1.9 13979 106 78 78 24 27 48 P P N N N N PSPC1 high in NP −2.8 0.012719761 −1.9 13980 30 70 22 12 12 9 N N N N N N ATN1 high in NP −1.8 0.012705362 −1.9 13981 865 1042 1404 696 678 659 N N N N N N DOST high in NP −3.3 0.01268342 −1.9 13982 55 208 61 24 17 28 N N N N N N SFT2D1 high in NP −3.5 0.012677249 −1.9 13983 58 57 42 15 31 10 N N N N N N ESRP1 high in NP −2.3 0.012671078 −1.9 13984 78 45 43 19 18 12 NA NA N N N N C19orf40 high in NP −3.2 0.01264845 −1.9 13985 229 273 101 41 43 86 N N N N N N RAD9A high in NP −2.7 0.012642279 −1.9 13986 131 179 94 38 53 68 N N N N N N PILRB high in NP −3.5 0.012600453 −1.9 13987 84 232 180 40 58 64 N N N N N N EIF3D high in NP −3.8 0.01258811 −1.9 13988 592 1768 1012 299 309 458 N N N N N N SEMA3B high in NP −3.7 0.01256754 −1.9 13989 3043 2995 7471 817 1890 1088 N N N N N N BAP1 high in NP −3.4 0.012483886 −1.9 13990 205 519 392 129 156 124 N N N N N N PKN3 high in NP −3.5 0.012474287 −1.9 13991 63 87 82 43 24 12 N N N N N N MAP3K11 high in NP −3.9 0.012456459 −1.9 13992 130 385 386 107 80 61 N N N N N N SDHAF2 high in NP −4.4 0.01244206 −1.9 13993 96 303 277 50 76 43 NA NA N N N N YIF1A high in NP −6.1 0.012406404 −1.9 13994 95 274 528 33 77 48 P N N N N N CAPN8 high in NP −3.4 0.012387891 −1.9 13995 521 1912 525 216 284 172 NA NA N N N N FAH high in NP −2.2 0.012376234 −1.9 13996 30 55 23 15 15 15 N N N N N N ITPA high in NP −2.9 0.012363206 −1.9 13997 40 39 21 8 18 10 N N N N N N RBM3 high in NP −4.0 0.012344693 −1.9 13998 402 444 245 55 129 161 N N N N P N SCPEP1 high in NP −2.3 0.01231178 −1.9 13999 20 25 17 14 12 12 N N N N N N ZC3HC1 high in NP −1.8 0.012299438 −1.9 14000 10 13 8 5 5 5 N N N N N N MAD1L1 high in NP −4.3 0.012269953 −1.9 14001 43 129 155 29 31 22 N N N N N N MCM9 high in NP −3.0 0.012256925 −1.9 14002 9 10 9 4 4 7 N N N N N N MIDN high in NP −2.2 0.012224013 −1.9 14003 1673 2081 1830 871 730 1160 N N N N N N MED22 high in NP −2.5 0.012206185 −1.9 14004 51 89 91 23 40 31 N N N N N N PLA2G2D high in NP −2.4 0.0121911 −1.9 14005 281 261 165 94 108 111 N N N N N N CXCL5 high in NP −5.1 0.012171215 −1.9 14006 35 92 39 8 24 4 N N N N N N TMEM88 high in NP −3.7 0.01212116 −1.9 14007 136 80 132 16 46 41 N N N N N N LRP5 high in NP −2.1 0.012114989 −1.9 14008 65 84 65 21 34 32 N N N N N N ABT1 high in NP −2.6 0.012108818 −1.9 14009 66 197 92 36 32 39 P P N N N N SMAD3 high in NP −2.6 0.012064248 −1.9 14010 707 1532 1124 367 511 510 N N N N N N WDR59 high in NP −2.7 0.012042307 −1.9 14011 97 114 62 25 41 37 N N N N N N SNRNP70 high in NP −4.3 0.012007337 −1.9 14012 514 1907 1717 223 251 461 N N N N N N ARL8A high in NP −2.6 0.011957282 −1.9 14013 625 1388 921 365 389 437 N N N N N N AR high in NP −2.4 0.011951111 −1.9 14014 19 40 16 9 7 10 P P N N N N MAPK8IP3 high in NP −3.1 0.011883914 −1.9 14015 394 659 952 258 234 307 N N N N N N SH3D20 high in NP −4.5 0.011845516 −1.9 14016 32 31 47 10 1 9 NA NA N N N N TXNDC16 high in NP −2.6 0.011827002 −1.9 14017 37 42 22 16 16 22 N N N N N N C8orf58 high in NP −2.3 0.011765291 −1.9 14018 19 26 27 13 7 10 N N N N N N XPOT high in NP −2.2 0.01170975 −1.9 14019 104 148 105 61 69 43 N N N N P N SYCE1 high in NP −3.9 0.011686437 −1.9 14020 51 27 20 4 7 15 P P N N N N ADIPOR1 high in NP −2.4 0.011665867 −1.9 14021 277 343 214 106 152 145 N N N N N N CAPN1 high in NP −3.1 0.011647353 −1.9 14022 565 1932 760 387 284 226 N N N N N N SCMH1 high in NP −2.7 0.011641182 −1.9 14023 32 57 44 12 17 23 N N N N N N C22orf13 high in NP −3.4 0.011554786 −1.9 14024 198 745 398 146 123 96 N N N N N N CES8 high in NP −4.2 0.011467019 −1.9 14025 54 24 38 6 6 20 NA NA N N N N R3HCC1 high in NP −4.4 0.011453991 −1.9 14026 129 234 376 53 97 53 N N N N N N WDR13 high in NP −2.2 0.011438906 −1.9 14027 302 337 439 156 175 198 N N N N N N ZNF625 high in NP −1.9 0.011426563 −1.9 14028 40 56 46 20 27 21 N N N N N N CCND1 high in NP −2.9 0.01139845 −1.9 14029 421 1118 445 200 242 159 N N N N N P SETD3 high in NP −4.3 0.011319597 −1.9 14030 48 80 36 12 15 29 N N N N N N AMFR high in NP −3.1 0.011313426 −1.9 14031 182 433 410 160 74 96 N N N N N N RPL36 high in NP −2.4 0.011255828 −1.9 14032 47455 30557 28913 13016 13760 16986 N N N N N N ZNF667 high in NP −2.3 0.011229087 −1.9 14033 26 20 18 9 12 9 N N N N N N FAM65A high in NP −3.1 0.011222916 −1.9 14034 295 915 524 185 199 207 N N N N N N ACSF3 high in NP −2.6 0.011199602 −2.0 14035 93 138 224 60 54 42 P P N N N N RASSF3 high in NP −2.7 0.01115709 −2.0 14036 10 24 13 5 5 5 N N N N N N DEF6 high in NP −3.4 0.011072065 −2.0 14037 40 38 30 11 21 13 N N N N N N CYTSA high in NP −2.2 0.01102681 −2.0 14038 196 323 295 136 152 112 NA NA N N N N TSC2 high in NP −2.2 0.010989098 −2.0 14039 151 259 233 137 109 102 N N N N N N CCS high in NP −5.2 0.010899959 −2.0 14040 21 66 83 15 8 11 N N N N N N GIPC1 high in NP −2.9 0.010801221 −2.0 14041 544 970 413 156 272 209 N N N N N N PRDM2 high in NP −2.7 0.010779279 −2.0 14042 242 263 169 94 104 110 N N N N N N SDHAF1 high in NP −3.9 0.010753223 −2.0 14043 20 52 51 10 11 12 NA NA N N N N LRRC8A high in NP −2.4 0.010734709 −2.0 14044 751 823 1035 405 321 556 N N N N N N GCN1L1 high in NP −2.5 0.010723738 −2.0 14045 155 221 198 50 104 71 N N N N N N SPAG7 high in NP −3.8 0.010676426 −2.0 14046 205 154 326 52 102 40 N N N N N N SND1 high in NP −2.1 0.010670255 −2.0 14047 668 981 993 418 466 434 N N P N N N SERPINA3 high in NP −4.1 0.010631857 −2.0 14048 2963 7386 1626 512 863 922 N N N N N N C17orf101 high in NP −4.2 0.010591402 −2.0 14049 17 54 49 7 8 13 NA NA N N N N LGALS1 high in NP −2.7 0.01058523 −2.0 14050 349 197 164 96 72 86 N N N N N N MIF high in NP −2.1 0.010547518 −2.0 14051 2533 3575 4063 1762 1621 1290 N N N N N N E2F1 high in NP −2.4 0.010541347 −2.0 14052 17 19 21 7 10 11 N N N N N N HAGHL high in NP −3.0 0.010510491 −2.0 14053 10 21 23 5 5 5 N N N N N N NHS high in NP −2.1 0.010496092 −2.0 14054 41 41 43 21 28 26 P P N N N N RHOT2 high in NP −5.4 0.010459065 −2.0 14055 149 436 589 97 96 80 N N N N N N IL17RD high in NP −3.1 0.010452894 −2.0 14056 64 120 75 39 53 41 N N N N N N NDUFB7 high in NP −2.7 0.010416552 −2.0 14057 113 165 167 62 79 36 N N N N N N ACADM high in NP −2.8 0.010403524 −2.0 14058 67 63 95 39 24 26 N N N N N N TMC7 high in NP −2.8 0.010397353 −2.0 14059 98 170 72 44 37 35 N N N N N N PLA2G15 high in NP −4.7 0.010378154 −2.0 14060 38 98 159 25 20 16 N N N N N N HOXB2 high in NP −5.6 0.010371983 −2.0 14061 33 18 7 6 2 5 N N N N N N ZNF512B high in NP −3.9 0.010362383 −2.0 14062 130 298 370 78 106 67 N N N N N N CYB5RL high in NP −2.4 0.010356212 −2.0 14063 163 143 98 59 48 67 NA NA N N N N PSMD8 high in NP −2.1 0.010339756 −2.0 14064 366 689 462 228 206 222 N N N N N N GADD45B high in NP −4.8 0.01019302 −2.0 14065 5166 2141 3205 432 672 1515 N N N N N N TMEM134 high in NP −3.5 0.010173821 −2.0 14066 152 196 436 67 88 49 N N N N N N KRTAP1-1 high in NP −3.0 0.010161478 −2.0 14067 7 5 5 4 2 2 N N N N N N DAZAP1 high in NP −3.6 0.010083996 −2.0 14068 551 1425 1052 318 386 307 N N N N N N TCEAL4 high in NP −5.0 0.010077825 −2.0 14069 54 69 47 12 4 25 N N N N N N MAP2K2 high in NP −2.4 0.010071654 −2.0 14070 879 1322 1143 499 599 389 N N N N N N CIAO1 high in NP −2.8 0.010065483 −2.0 14071 254 254 157 79 71 107 N N N N N N CSTF1 high in NP −5.7 0.010055883 −2.0 14072 41 66 49 10 26 6 N N N N N N ANKRD30A high in NP −2.7 0.01004217 −2.0 14073 19 81 20 6 6 6 N N N N N N DCAF11 high in NP −3.0 0.010022285 −2.0 14074 141 93 110 53 38 36 NA NA N N N N TSPAN13 high in NP −5.1 0.009989372 −2.0 14075 78 85 24 7 12 19 N N N N N N C1orf122 high in NP −6.4 0.009924232 −2.0 14076 83 200 67 14 39 6 N N N N N N ATM high in NP −2.0 0.009896119 −2.0 14077 56 61 49 31 28 34 N N N N N N SF3B14 high in NP −2.4 0.009883777 −2.0 14078 128 211 107 48 57 69 N N N N N N GHDC high in NP −3.6 0.009871434 −2.0 14079 20 62 50 8 15 11 N N N N N N TTLL3 high in NP −2.4 0.009856349 −2.0 14080 303 269 297 89 147 149 N N N N N N GFOD1 high in NP −3.3 0.009817951 −2.0 14081 109 57 48 26 26 20 N N N N N N PEX1 high in NP −2.2 0.009770639 −2.0 14082 32 55 36 18 21 14 N N N N N N GRINA high in NP −2.8 0.009649273 −2.0 14083 331 708 570 218 225 228 N N N N N N EIF4EBP1 high in NP −2.8 0.009643102 −2.0 14084 388 603 305 212 165 132 N N N N N N TARSL2 high in NP −4.6 0.009636931 −2.0 14085 12 35 24 7 7 7 N N N N N N EID1 high in NP −2.1 0.009623903 −2.0 14086 122 90 79 40 43 41 N N N N N N C11orf31 high in NP −1.9 0.009611561 −2.0 14087 345 315 307 181 186 157 N N N N N N UGDH high in NP −4.6 0.009575219 −2.0 14088 307 228 120 57 76 49 N N N N N N GTPBP6 high in NP −2.0 0.009489509 −2.0 14089 185 171 167 95 84 108 N N N N N N CAPS high in NP −2.8 0.009479909 −2.0 14090 22 54 35 11 8 14 N N N N N N ARL6IP4 high in NP −2.2 0.009464824 −2.0 14091 220 358 217 139 120 122 N N N N N N THAP1 high in NP −3.4 0.009440826 −2.0 14092 7 20 7 2 2 2 N N N N N N CD9 high in NP −4.9 0.009418884 −2.0 14093 336 272 117 74 29 59 N N N N N N HOMER2 high in NP −5.1 0.009412713 −2.0 14094 118 453 297 32 67 76 N N N N N N SH3GLB2 high in NP −2.2 0.009372257 −2.0 14095 746 1141 1051 503 398 495 N N N N N N STAP2 high in NP −4.4 0.009337287 −2.0 14096 92 56 119 6 30 20 N N N N P N FAM22A high in NP −5.5 0.009315346 −2.0 14097 12 29 32 4 4 10 N N N N N N MLPH high in NP −3.8 0.009309174 −2.0 14098 106 73 42 26 15 16 N N N N N N SVOPL high in NP −2.7 0.009281747 −2.0 14099 11 7 9 3 6 3 N N N N N N PPP2R1A high in NP −3.4 0.009246777 −2.0 14100 613 2051 986 380 333 278 N N N N N N MOSC1 high in NP −2.5 0.009211122 −2.0 14101 10 9 14 6 6 6 N N N N N N ALDH5A1 high in NP −2.3 0.009165181 −2.0 14102 29 35 27 15 13 18 N N N N N N PTPRF high in NP −3.0 0.009111012 −2.0 14103 924 1221 1470 515 350 660 N N N N N N ARRDC1 high in NP −4.5 0.009072614 −2.0 14104 246 718 590 142 170 121 N N N N N N TTC18 high in NP −2.4 0.009066443 −2.0 14105 15 15 13 7 10 7 N N N N N N SBF1P1 high in NP −3.2 0.009060272 −2.0 14106 1280 727 1037 230 428 347 NA NA N N N N KIAA1683 high in NP −2.8 0.009011588 −2.0 14107 32 26 31 16 16 16 N N N N N N TMEM184A high in NP −2.7 0.009005417 −2.0 14108 196 179 377 85 83 78 N N N N N N CHSY1 high in NP −3.3 0.008999246 −2.0 14109 188 231 182 79 51 105 N N N N N N KRT10 high in NP −4.7 0.008993075 −2.0 14110 22 83 36 8 12 11 N N N N N N TP53TG1 high in NP −3.2 0.008986903 −2.0 14111 70 62 52 23 19 7 N N N N N N VEZT high in NP −3.7 0.008969761 −2.0 14112 98 214 58 24 33 30 N N N N N N ZER1 high in NP −2.3 0.008935477 −2.0 14113 334 454 568 216 231 171 N N N N N N DTX2 high in NP −3.1 0.008895708 −2.1 14114 143 271 161 48 93 56 N N N N N N PUM1 high in NP −3.1 0.008831253 −2.1 14115 157 394 156 68 75 86 N N N N N N NARFL high in NP −3.3 0.008818911 −2.1 14116 17 62 37 11 9 9 N N N N N N SEMG2 high in NP −3.2 0.008790798 −2.1 14117 21 2 2 1 1 1 N N N N N N OUTA high in NP −3.9 0.00877297 −2.1 14118 822 346 410 93 143 178 N N N N N N BLOC1S3 high in NP −2.2 0.008751714 −2.1 14119 32 44 30 14 17 11 N N N N N N ACAD11 high in NP −3.7 0.008738686 −2.1 14120 185 97 173 56 47 42 N N N N N N TWF2 high in NP −5.4 0.008703031 −2.1 14121 50 186 152 33 24 16 N N N N N N PSMAG high in NP −2.6 0.00869686 −2.1 14122 303 637 269 118 146 145 N N N N N N UQCRH high in NP −2.3 0.008671489 −2.1 14123 2207 2263 1610 912 830 1058 N N N N N N MAPK7 high in NP −2.4 0.008659147 −2.1 14124 117 123 132 54 62 31 N N N N N N ANO10 high in NP −2.7 0.008646119 −2.1 14125 111 175 181 75 64 38 N N N N N N C10orf57 high in NP −2.0 0.008585779 −2.1 14126 13 14 10 5 5 5 N N N N N N CDK2 high in NP −3.0 0.008548066 −2.1 14127 96 126 147 27 49 54 N N N N N N COPB2 high in NP −3.5 0.008511039 −2.1 14128 122 145 60 41 28 22 N N N N N N RNF166 high in NP −8.2 0.008467156 −2.1 14129 11 48 50 7 3 3 N N N N N N NUCB2 high in NP −3.4 0.008439043 −2.1 14130 188 377 123 64 61 58 N N N N N N ZDHHC8P high in NP −2.1 0.008407501 −2.1 14131 NA NA NA NA NA NA N N N N N N TRIM45 high in NP −3.7 0.00830602 −2.1 14132 22 13 24 6 12 6 N N N N N N SLU7 high in NP −2.3 0.008293678 −2.1 14133 136 211 134 65 81 68 N N N N N N MST1P2 high in NP −7.5 0.008243623 −2.1 14134 62 40 56 1 14 9 NA NA N N N N ZNF506 high in NP −2.5 0.008229224 −2.1 14135 13 11 13 5 8 5 N N N N N N GGA1 high in NP −3.4 0.008198368 −2.1 14136 323 301 521 194 96 97 N N N N N N RNASEK high in NP −2.7 0.00818534 −2.1 14137 1604 2599 3311 957 982 708 N N N N N N LOC139201 high in NP −3.3 0.008166827 −2.1 14138 55 38 28 7 19 12 NA NA N N N N ZNF44 high in NP −3.7 0.008140085 −2.1 14139 52 63 36 12 26 14 N N N N N N TMEM101 high in NP −2.9 0.008103744 −2.1 14140 114 213 183 44 81 45 N N N N N N TNPO2 high in NP −2.7 0.008059174 −2.1 14141 148 425 196 89 82 68 N N N N N N GUK1 high in NP −3.3 0.008027633 −2.1 14142 810 709 393 170 227 236 N N N N N P STK36 high in NP −2.6 0.008021462 −2.1 14143 38 45 25 12 13 16 N N N N N N RRAGC high in NP −2.4 0.00800912 −2.1 14144 337 283 266 133 107 157 N N N N N N PCBP4 high in NP −5.3 0.008002948 −2.1 14145 112 68 194 39 21 25 N N N N N N EGFL8 high in NP −2.8 0.007996777 −2.1 14146 32 37 62 14 15 18 N N N N N N RAD54L2 high in NP −2.3 0.007949465 −2.1 14147 72 153 100 47 44 41 N N N N N N METRN high in NP −3.5 0.00793438 −2.1 14148 117 283 232 58 59 46 P P N N N N RPL41 high in NP −1.9 0.007928209 −2.1 14149 127927 78691 78650 47221 47238 47213 N N N N N N STAC3 high in NP −3.0 0.007889125 −2.1 14150 7 3 6 2 2 2 N N N N N N MAP2K7 high in NP −2.1 0.007882954 −2.1 14151 481 483 564 292 279 322 N N N N N N U2AF2 high in NP −3.7 0.007876783 −2.1 14152 605 696 1291 199 331 300 N N N N P N ZNF124 high in NP −2.5 0.007847984 −2.1 14153 11 9 9 2 5 2 N N N N N N RAB15 high in NP −2.2 0.007793815 −2.1 14154 132 164 167 70 75 92 N N N N N N PPFIBP2 high in NP −2.7 0.007787644 −2.1 14155 47 47 30 18 13 21 N N N N N N BRMS1 high in NP −3.7 0.007781473 −2.1 14156 32 41 19 13 9 14 N N N N N N ZNF771 high in NP −4.6 0.007775302 −2.1 14157 40 25 49 9 14 5 N N N N N N MAFK high in NP −4.1 0.007769131 −2.1 14158 2443 1607 4697 410 648 869 N N N N N N FAM63B high in NP −2.5 0.007756788 −2.1 14159 53 71 73 39 28 30 N N N N N N RPL13AP5 high in NP −4.3 0.007735532 −2.1 14160 400 203 295 44 66 122 NA NA N N N N MAPT high in NP −3.6 0.007647765 −2.1 14161 302 137 133 59 51 38 N P N N N N BRD9 high in NP −4.1 0.007636794 −2.1 14162 125 239 283 37 74 67 N N N N N N TCTN2 high in NP −4.0 0.007630623 −2.1 14163 72 43 98 12 9 24 N N N N N N TRPT1 high in NP −3.0 0.007624451 −2.1 14164 24 16 15 8 4 4 N N N N N N SMARCD2 high in NP −2.8 0.007613481 −2.1 14165 106 182 178 71 60 44 N N N N N N SAFB high in NP −2.5 0.007577825 −2.1 14166 60 93 55 28 26 33 N N N N N N CSRP1 high in NP −4.3 0.007565483 −2.1 14167 10059 5673 10812 1130 2470 3089 N N N N N N MLH3 high in NP −1.9 0.007550398 −2.1 14168 48 62 55 26 29 30 N N N N N N EIF2C2 high in NP −3.0 0.007535313 −2.1 14169 181 220 231 69 77 113 N N N N N N PKIG high in NP −4.1 0.007501714 −2.1 14170 121 188 99 47 49 17 N N N N N P AMBP high in NP −2.1 0.007495543 −2.1 14171 7 6 4 2 2 2 N N N N N N FLJ23867 high in NP −2.3 0.007475658 −2.1 14172 69 102 73 44 34 29 NA NA N N N N NTAN1 high in NP −4.0 0.007469487 −2.1 14173 11 28 10 3 3 6 N N N N N N ZNF689 high in NP −3.5 0.007454402 −2.1 14174 15 28 14 5 8 3 N N N N N N ANKRD52 high in NP −3.3 0.007420804 −2.1 14175 183 433 358 136 106 113 N N N N N N FEZ2 high in NP −2.9 0.007414632 −2.1 14176 140 218 175 49 89 68 N N N N N N GDPD3 high in NP −3.0 0.007382405 −2.1 14177 58 59 132 19 22 25 N N N N N N KATNAL2 high in NP −3.2 0.007376234 −2.1 14178 12 6 5 4 4 4 N N N N N N LRRFIP2 high in NP −3.3 0.007341264 −2.1 14179 2058 1702 1957 505 662 1021 N N N N N N RILPL2 high in NP −3.3 0.007335093 −2.1 14180 27 21 11 2 2 8 N N N N N N LOC100130872 high in NP −2.0 0.007215099 −2.1 14181 16 17 18 11 11 11 NA NA N N N N TBC1D10B high in NP −3.1 0.007208928 −2.1 14182 84 107 126 29 57 35 N N N N N N PPM1G high in NP −2.7 0.007202756 −2.1 14183 854 1240 1749 550 566 462 N N N N N N ABHD14A high in NP −2.7 0.00715133 −2.1 14184 15 22 18 9 9 10 N N N N N N SRP19 high in NP −3.0 0.007132131 −2.1 14185 8 7 4 3 3 3 N N N N N N IMPDH2 high in NP −3.9 0.00712596 −2.1 14186 383 368 200 56 106 110 N N N N N N MRPS33 high in NP −9.6 0.007119789 −2.1 14187 64 49 42 4 23 5 N N N N N N MMP14 high in NP −3.1 0.007105389 −2.1 14188 49 109 84 36 29 25 N N N N N N AKIRIN1 high in NP −4.5 0.007099218 −2.1 14189 453 347 267 75 76 168 N N N N N N LNX2 high in NP −2.9 0.00708619 −2.1 14190 30 81 44 17 12 15 N N N N N N PNP high in NP −2.9 0.007018308 −2.2 14191 626 494 529 179 193 292 NA NA N N N N EBPL high in NP −2.7 0.00699568 −2.2 14192 23 12 11 8 6 6 N N N N N N LENG9 high in NP −5.1 0.006948368 −2.2 14193 298 205 228 43 49 111 N N N N N N MYO9B high in NP −3.3 0.006908598 −2.2 14194 296 184 307 76 95 84 N N N N N N KDM4B high in NP −2.4 0.006877743 −2.2 14195 74 72 54 23 28 26 NA NA N N N N PHRF1 high in NP −2.8 0.006871572 −2.2 14196 294 433 596 166 191 164 N N N N N P PHC2 high in NP −5.3 0.006856487 −2.2 14197 214 1141 431 84 110 116 N N N N N N UQCRQ high in NP −3.2 0.006840716 −2.2 14198 143 159 99 33 66 44 N N N N N N CHI3L2 high in NP −4.2 0.006834545 −2.2 14199 980 2894 1117 474 371 261 N N N N N N ASH2L high in NP −4.7 0.00681946 −2.2 14200 26 104 50 13 11 6 N N N N N N FCGRT high in NP −2.8 0.006813289 −2.2 14201 214 359 247 83 101 127 N N N N N N C14orf93 high in NP −2.3 0.006774205 −2.2 14202 13 11 14 8 8 8 N N N N N N SCUBE2 high in NP −6.3 0.006768033 −2.2 14203 182 99 65 22 14 37 N N N N N N KRT18 high in NP −3.9 0.006761862 −2.2 14204 54 52 74 11 25 10 N N N N N N RHOG high in NP −2.4 0.00669398 −2.2 14205 340 469 319 137 197 165 N N N N N N ARTN high in NP −6.2 0.006687809 −2.2 14206 68 51 333 7 15 11 N N N N N N PPP1CC high in NP −3.6 0.006676152 −2.2 14207 113 303 156 41 57 64 N N N N N N H1FX high in NP −4.7 0.00661924 −2.2 14208 1398 525 516 256 173 132 N N N N N N CUL7 high in NP −2.8 0.006591813 −2.2 14209 60 110 103 32 37 37 N N N N N N SF3A2 high in NP −2.8 0.006550672 −2.2 14210 468 590 773 211 243 302 N N N N N N EMID1 high in NP −4.1 0.006544501 −2.2 14211 85 44 58 14 21 11 N N N N N N ZC3H11A high in NP −4.0 0.006486218 −2.2 14212 91 286 150 55 41 49 N N N N N N SLC25A6 high in NP −2.8 0.006471133 −2.2 14213 5807 4314 4211 1404 2138 2115 N N N N N N NEDD4L high in NP −2.9 0.006450562 −2.2 14214 1435 1120 1047 374 514 599 N N N N P N C3orf49 high in NP −4.6 0.006444391 −2.2 14215 9 4 4 1 1 4 NA NA N N N N TRIM28 high in NP −2.6 0.00643822 −2.2 14216 1807 2423 3631 758 942 1055 N N N N N N HSD17B3 high in NP −3.0 0.006413535 −2.2 14217 7 7 11 2 2 2 N N N N N N BUD31 high in NP −2.8 0.006407364 −2.2 14218 37 68 34 15 17 20 N N N N N N ASCC2 high in NP −5.7 0.006359366 −2.2 14219 26 78 82 14 16 13 N N N N N N TPX2 high in NP −8.8 0.006309312 −2.2 14220 45 25 44 5 14 2 N N N N N N ENSA high in NP −2.5 0.006224973 −2.2 14221 204 179 147 56 70 72 N N N N N N LIG1 high in NP −3.0 0.006218801 −2.2 14222 36 46 57 18 12 18 N N N N N N DAP high in NP −3.4 0.00621263 −2.2 14223 105 80 49 19 25 15 N N N N N N TINF2 high in NP −2.3 0.006199602 −2.2 14224 22 38 23 11 12 12 N N N N N N PLXND1 high in NP −4.3 0.006183832 −2.2 14225 74 189 180 52 42 30 N N N N N N INPP5J high in NP −3.4 0.006164632 −2.2 14226 33 57 81 20 16 19 N N N N N N TMEM38A high in NP −2.4 0.006155033 −2.2 14227 9 12 10 4 4 4 N N N N N N IFI27L1 high in NP −2.1 0.006148862 −2.2 14228 8 6 5 3 3 3 N N N N N N 40788 high in NP −4.3 0.006129663 −2.2 14229 284 437 178 65 84 98 NA NA N N N N DDB1 high in NP −2.9 0.006076865 −2.2 14230 297 517 517 158 188 189 N N N N N N MGAT4B high in NP −6.1 0.006070694 −2.2 14231 215 770 458 93 93 130 N N N N N N FBX021 high in NP −4.5 0.006064523 −2.2 14232 76 324 128 32 37 27 N N N N N N B3GALNT1 high in NP −2.8 0.006038467 −2.2 14233 19 23 12 8 8 6 N N N N N N C17orf70 high in NP −3.9 0.006022696 −2.2 14234 NA NA NA NA NA NA N N N N N N DUSP4 high in NP −3.8 0.006016525 −2.2 14235 246 203 121 59 63 66 N N N N P N COX4NB high in NP −2.1 0.005983612 −2.2 14236 154 200 209 109 98 86 N N N N N N CILP2 high in NP −3.7 0.005945214 −2.2 14237 14 24 27 6 8 6 N N N N N N SUSD2 high in NP −2.9 0.005939043 −2.2 14238 35 48 77 15 18 14 N N N N N N FAM82A2 high in NP −4.7 0.005917101 −2.2 14239 46 154 100 21 27 24 N N N N N N EPN1 high in NP −6.6 0.005902016 −2.2 14240 132 411 514 82 73 66 N N N N N N CENPH high in NP −4.4 0.005874589 −2.2 14241 83 85 28 19 8 11 N N N N N N CDH1 high in NP −2.7 0.005848533 −2.2 14242 3398 3140 2082 923 1211 1161 N N N N N N ATAD2 high in NP −2.6 0.005763508 −2.2 14243 54 42 39 24 18 20 N N N N N N URM1 high in NP −2.2 0.005757337 −2.2 14244 33 55 41 19 17 16 N N N N N N JOSD1 high in NP −2.4 0.005746366 −2.2 14245 418 334 442 154 149 198 N N N N N N COBRA1 high in NP −10.7 0.00569014 −2.2 14246 86 487 379 41 53 24 N N N N N N ABHD14B high in NP −4.5 0.005658598 −2.2 14247 271 184 303 37 75 90 N N N N N N CEP290 high in NP −3.0 0.005652427 −2.2 14248 24 23 22 10 14 8 N N N N N N ZNF775 high in NP −7.2 0.005637342 −2.2 14249 7 9 26 2 2 2 N N N N N N CEBPG high in NP −2.4 0.005607172 −2.3 14250 95 130 82 42 47 45 N N N N N N PDK2 high in NP −2.6 0.005590716 −2.3 14251 37 44 52 22 18 13 N N N N N N EEF1A1 high in NP −5.5 0.005584545 −2.3 14252 518 589 362 85 126 212 N N N N N N SLC25A14 high in NP −2.5 0.005544089 −2.3 14253 17 15 11 6 6 6 N N N N N N PM20D2 high in NP −2.5 0.005531747 −2.3 14254 48 80 44 25 22 18 N N N N N N CCNB2 high in NP −4.6 0.005525576 −2.3 14255 13 5 8 5 5 5 N N N N N N ACBD4 high in NP −5.3 0.005519405 −2.3 14256 26 52 83 11 6 11 N N N N N N ANXA3 high in NP −5.1 0.005507063 −2.3 14257 137 234 191 86 49 30 N N N N N N PRDX2 high in NP −2.7 0.00549472 −2.3 14258 270 278 191 88 116 77 N N N N N N PHYHD1 high in NP −2.8 0.005479635 −2.3 14259 86 86 114 33 31 43 N N N N N N SNX17 high in NP −3.3 0.005452208 −2.3 14260 42 38 60 17 21 16 N N N N N N NUP188 high in NP −5.3 0.005430266 −2.3 14261 101 361 232 53 49 59 N N N N N N NIT2 high in NP −2.8 0.005424095 −2.3 14262 182 279 221 58 99 88 N N N N N N FGFBP3 high in NP −2.2 0.005401467 −2.3 14263 13 10 10 5 5 5 N N N N N N LOC643763 high in NP −2.1 0.005374726 −2.3 14264 19 25 19 11 9 9 NA NA N N N N CRYZL1 high in NP −2.9 0.005352784 −2.3 14265 15 36 15 6 6 6 N N N N N N CMTM3 high in NP −3.1 0.005346613 −2.3 14266 325 538 401 121 173 188 N N N N N N FAM195B high in NP −4.6 0.005313014 −2.3 14267 481 845 1610 137 197 244 NA NA N N N N ZNF682 high in NP −2.1 0.005306843 −2.3 14268 12 9 10 7 7 7 N N N N N N PLCB4 high in NP −3.5 0.005300672 −2.3 14269 75 46 36 21 17 17 N N N N N N CCDC53 high in NP −3.8 0.005294501 −2.3 14270 27 23 14 5 3 9 N N N N N N DDAH2 high in NP −2.7 0.005275987 −2.3 14271 1276 1195 2113 577 474 519 N N N N N N MTMR11 high in NP −3.5 0.005269816 −2.3 14272 75 95 63 36 25 19 N N N N N N EIF3K high in NP −5.0 0.005249931 −2.3 14273 750 356 465 66 113 174 N N N N N N SNRNP35 high in NP −2.9 0.005214276 −2.3 14274 25 43 40 13 14 8 N N N N N N HSD17B8 high in NP −3.9 0.005201934 −2.3 14275 31 27 25 4 7 12 N N N N N N E2F5 high in NP −3.6 0.005195762 −2.3 14276 22 27 15 6 12 6 N N N N N N VAV3 high in NP −8.6 0.005165592 −2.3 14277 105 381 444 32 51 55 N N N N N N LRRC48 high in NP −5.3 0.005159421 −2.3 14278 32 16 35 8 8 11 N N N N N N POLR1E high in NP −3.3 0.005091539 −2.3 14279 196 147 117 39 53 60 N N N N N N RPS9 high in NP −4.5 0.005085368 −2.3 14280 5630 9393 13402 1601 1939 2952 N N N N N N EEF1G high in NP −5.1 0.005047655 −2.3 14281 8602 4514 3281 679 1112 1547 N N N N N N GTPBP2 high in NP −3.7 0.005035313 −2.3 14282 349 418 196 87 77 109 N N N N N N FAM76A high in NP −2.8 0.00497703 −2.3 14283 31 30 22 12 15 9 N N N N N N MOGS high in NP −2.8 0.004944117 −2.3 14284 77 124 132 28 40 38 NA NA N N N N CYP2J2 high in NP −2.0 0.004937946 −2.3 14285 8 9 7 3 3 3 N N N N N N PMPCA high in NP −11.3 0.004931775 −2.3 14286 81 298 431 22 21 53 N N N N N N ACTN4 high in NP −2.4 0.004925603 −2.3 14287 3166 4447 4144 1575 2055 1480 N N N N N N PPP2R5C high in NP −3.1 0.004913261 −2.3 14288 219 151 195 64 84 72 N N N N N N NAPA high in NP −3.1 0.004900919 −2.3 14289 458 1075 432 187 174 148 N N N N N N ZHX1 high in NP −2.5 0.004885834 −2.3 14290 46 54 38 20 19 17 N N N N N N MPST high in NP −5.4 0.004879663 −2.3 14291 208 247 593 83 82 46 N N N N N N CTSB high in NP −2.4 0.004844693 −2.3 14292 1749 2528 2027 1001 1070 854 N N N N N N DIS3L high in NP −2.7 0.004833722 −2.3 14293 927 922 621 315 307 376 N N N N N N INPPL1 high in NP −2.7 0.004815894 −2.3 14294 419 825 439 216 183 186 N N N N P N AHSA2 high in NP −5.6 0.004794638 −2.3 14295 76 39 32 9 7 18 N N N N N N C17orf28 high in NP −2.5 0.004778867 −2.3 14296 462 573 698 288 305 192 N N N N N N HINT2 high in NP −4.7 0.004766525 −2.3 14297 82 96 118 37 20 13 N N N N N N C12orf11 high in NP −6.8 0.004755554 −2.3 14298 108 109 91 20 49 22 N N N N N N GSTZ1 high in NP −5.2 0.004727441 −2.3 14299 29 41 66 12 14 6 N N N N N P WDR33 high in NP −2.6 0.00472127 −2.3 14300 125 153 117 47 51 56 N N N N N N BARD1 high in NP −3.2 0.004702756 −2.3 14301 18 14 9 5 5 5 N N N N N N SLC37A4 high in NP −3.6 0.004696585 −2.3 14302 16 36 26 10 8 8 N N N N N N PLSCR3 high in NP −4.8 0.004679443 −2.3 14303 111 368 211 49 41 54 N N N N N N FTSJD2 high in NP −5.6 0.004656816 −2.3 14304 117 286 312 47 66 50 N N N N N N TMEM214 high in NP −2.6 0.004650645 −2.3 14305 241 386 337 118 155 122 N N N N N N ACAD10 high in NP −3.1 0.00463556 −2.3 14306 55 48 62 18 12 21 N N N N N N SFRS2 high in NP −3.4 0.004609504 −2.3 14307 1371 1662 1336 331 499 662 N N N N N N CCDC101 high in NP −8.2 0.004567677 −2.3 14308 70 149 182 11 38 19 N N N N N N S100A14 high in NP −3.3 0.004561506 −2.3 14309 7828 11973 13611 3256 4411 2385 N N N N N N COX5B high in NP −3.5 0.004555335 −2.3 14310 66 103 53 21 27 13 N N N N N N C2orf81 high in NP −5.8 0.004549163 −2.3 14311 36 19 17 5 5 11 NA NA N N N N TRIP6 high in NP −3.3 0.004542992 −2.3 14312 543 799 1227 261 297 220 N N N N N N CYP2D7P1 high in NP −5.0 0.004515565 −2.3 14313 10 14 14 4 2 5 N N N N N N APOBEC3C high in NP −2.5 0.004498423 −2.3 14314 39 39 36 15 14 20 N N N N N N KATNB1 high in NP −5.0 0.004455225 −2.4 14315 112 173 243 53 44 23 N N N N N N PMAIP1 high in NP −5.8 0.004433969 −2.4 14316 295 189 140 22 34 66 N N N N N N SIN3B high in NP −4.1 0.004386657 −2.4 14317 319 847 500 144 181 129 N N N N N N EREG high in NP −9.6 0.004377057 −2.4 14318 113 210 45 25 10 10 P P N N N N RHPN1 high in NP −3.2 0.004358544 −2.4 14319 223 197 347 68 93 76 N N N N N N ZNF580 high in NP −3.4 0.00434003 −2.4 14320 99 99 81 42 30 20 N N N N N N NDUFA11 high in NP −4.5 0.004308489 −2.4 14321 355 881 472 157 179 98 N N N N P N DULLARD high in NP −3.9 0.004298889 −2.4 14322 59 130 60 14 23 21 N N N N N N AUH high in NP −2.6 0.004286547 −2.4 14323 24 20 21 11 8 9 N N N N N N JOSD2 high in NP −6.1 0.004274205 −2.4 14324 58 138 216 24 22 22 N N N N N N CRB3 high in NP −9.2 0.004261862 −2.4 14325 62 216 266 24 20 27 N N N N N N GSDMD high in NP −6.8 0.004255691 −2.4 14326 70 236 250 27 42 22 N N N N N N ACSF2 high in NP −2.7 0.00424952 −2.4 14327 129 158 182 65 73 53 N N N N N N COL9A2 high in NP −3.6 0.004243349 −2.4 14328 54 86 126 21 17 28 N N N N N N PFKL high in NP −2.7 0.004223464 −2.4 14329 1203 1359 1963 502 571 588 N N N N N N NFRKB high in NP −2.8 0.004217293 −2.4 14330 210 308 339 109 137 124 N N N N N N ZNF385B high in NP −6.0 0.004211122 −2.4 14331 31 9 23 3 3 3 N N N N N N UBAC2 high in NP −3.2 0.004158324 −2.4 14332 30 33 19 10 10 10 N N N N N N VPS37D high in NP −5.6 0.004130897 −2.4 14333 35 31 40 13 7 7 N N N N N N ZDHHC7 high in NP −2.5 0.004110326 −2.4 14334 686 927 739 309 397 307 N N N N N N CDK9 high in NP −5.1 0.004096613 −2.4 14335 280 695 620 120 153 148 N N N N N N H2AFX high in NP −3.4 0.004059586 −2.4 14336 144 194 138 35 58 68 N N N N N N FXYD3 high in NP −2.3 0.004047244 −2.4 14337 2773 2341 3264 1340 1097 1167 N N N N N N C19orf20 high in NP −3.6 0.004041072 −2.4 14338 34 57 61 10 17 14 N N N N N N APH1B high in NP −3.0 0.00402873 −2.4 14339 61 115 109 37 28 24 N N N N N N NUP160 high in NP −3.2 0.004006103 −2.4 14340 35 64 52 17 22 20 N N N N N N LGALS3BP high in NP −3.0 0.003999931 −2.4 14341 76 156 99 42 45 35 N N N N N N ATP6AP1 high in NP −2.6 0.00399376 −2.4 14342 180 265 265 80 110 79 N N N N N N POM121L1P high in NP −6.1 0.003944391 −2.4 14343 36 3 6 1 1 1 NA NA N N N N ECHS1 high in NP −2.9 0.003925878 −2.4 14344 70 59 79 25 30 22 N N N N N N SLC27A1 high in NP −2.6 0.003888165 −2.4 14345 85 92 67 30 37 25 N N N N N N COPE high in NP −3.4 0.003869652 −2.4 14346 337 703 459 166 179 127 N N N N N N TMEM5 high in NP −2.7 0.003863481 −2.4 14347 45 42 37 12 19 16 N N N N N N GLTPD2 high in NP −6.0 0.00380794 −2.4 14348 6 6 14 1 1 1 N N N N N N ULK3 high in NP −2.5 0.003764742 −2.4 14349 60 69 47 26 26 25 N N N N N N LOC646999 high in NP −8.9 0.003733886 −2.4 14350 22 34 46 6 8 11 N N N N N N C8orf45 high in NP −3.3 0.003713316 −2.4 14351 18 20 15 12 9 9 N N N N N N CRIP2 high in NP −3.3 0.003697545 −2.4 14352 674 625 527 132 250 221 N N N N N N TSPAN1 high in NP −4.8 0.003683832 −2.4 14353 56 96 57 21 11 4 N N N N N N RPL35 high in NP −5.8 0.00367766 −2.4 14354 10276 5563 14219 1073 1743 2477 N N N N N N BANF1 high in NP −3.1 0.003671489 −2.4 14355 265 441 390 148 140 139 N N N N N N SYNGR2 high in NP −4.6 0.003609092 −2.4 14356 1017 2699 819 288 323 242 N N N N N N KHSRP high in NP −3.2 0.003585093 −2.4 14357 294 265 200 92 93 101 N N N N N N SF3B5 high in NP −3.0 0.003534353 −2.5 14358 1081 1294 1247 375 572 430 N N N N N N TICAM1 high in NP −3.1 0.003506925 −2.5 14359 328 375 253 111 95 133 N N N N N N NR2E3 high in NP −3.3 0.003484298 −2.5 14360 11 16 13 2 2 6 N N N N N N TAGLN2 high in NP −3.3 0.003478127 −2.5 14361 1278 1373 915 515 465 421 N N N N N N MUSTN1 high in NP −5.3 0.003471956 −2.5 14362 10 9 7 2 2 5 N N N N N N ZFPL1 high in NP −3.0 0.003465784 −2.5 14363 89 141 100 44 35 26 N N N N N N RPL11 high in NP −5.0 0.003453442 −2.5 14364 10281 5707 8868 1134 1775 2591 N N N N N N PLEKHA8 high in NP −3.0 0.003434929 −2.5 14365 8 4 4 3 3 3 N N N N N N ZNF238 high in NP −2.9 0.003402016 −2.5 14366 81 73 55 26 24 26 N N N N N N ZBTB22 high in NP −2.9 0.003382817 −2.5 14367 42 71 75 18 25 22 N N N N N N LOC729176 high in NP −5.3 0.003370474 −2.5 14368 9 9 5 1 4 1 N N N N N N MAP2K4 high in NP −2.3 0.003360875 −2.5 14369 60 56 47 21 25 27 N N N N N N NPHP4 high in NP −4.5 0.003354704 −2.5 14370 75 67 86 16 27 27 N P N N N N OTUD5 high in NP −5.8 0.003299163 −2.5 14371 194 429 497 69 97 95 N N N N N N EXOC3 high in NP −6.7 0.003286821 −2.5 14372 98 342 212 39 34 45 N N N N N N BMS1P5 high in NP −9.8 0.003265565 −2.5 14373 58 64 25 3 4 14 N N N N N N LRRC29 high in NP −2.4 0.003236081 −2.5 14374 7 6 6 2 2 2 N N N N N N SPTBN1 high in NP −5.1 0.003229909 −2.5 14375 358 1055 390 108 106 152 N N N N N N VKORC1 high in NP −5.6 0.003199054 −2.5 14376 44 34 22 5 12 5 N N N N N N ZNF598 high in NP −3.7 0.003170941 −2.5 14377 855 2099 1193 347 319 397 N N N N N N RANGRF high in NP −3.5 0.003155856 −2.5 14378 23 21 11 3 6 3 N N N N N N LOC100233209 high in NP −2.7 0.003137342 −2.5 14379 228 254 213 102 84 104 NA NA N N N N RAE1 high in NP −3.9 0.003131171 −2.5 14380 43 35 24 8 11 14 N N N N P N CNTROB high in NP −4.2 0.003125 −2.5 14381 69 84 164 18 27 19 N N N N N N PPME1 high in NP −3.6 0.003118829 −2.5 14382 87 176 125 31 33 49 N N N N N N GPAA1 high in NP −12.1 0.003109229 −2.5 14383 132 533 606 52 65 48 N N N N N N COQ10A high in NP −4.4 0.003103058 −2.5 14384 26 22 20 6 12 6 N N N N N N DUSP10 high in NP −5.4 0.003083173 −2.5 14385 93 41 27 12 11 11 N N N N N N U2AF1L4 high in NP −3.8 0.003070831 −2.5 14386 84 62 64 23 24 15 N N N N N N SAE1 high in NP −3.6 0.003049575 −2.5 14387 159 277 218 85 67 56 N N N N N N TIMM10 high in NP −2.7 0.003012548 −2.5 14388 129 126 97 43 50 36 N N N N N N NUMA1 high in NP −2.9 0.003000206 −2.5 14389 638 945 635 264 241 328 N N N N N N REEP6 high in NP −3.1 0.002994035 −2.5 14390 142 170 149 51 50 24 N N N N N N RPN1 high in NP −3.7 0.00297895 −2.5 14391 437 505 277 100 123 138 N N N N N N RALGDS high in NP −4.3 0.002963865 −2.5 14392 2154 2172 1668 436 551 797 N N N N N N CLCN7 high in NP −7.3 0.002957693 −2.5 14393 215 636 640 94 111 78 N N N N N N MGMT high in NP −6.7 0.002942608 −2.5 14394 38 87 96 13 15 14 N N N N N N TLCD1 high in NP −2.8 0.002915867 −2.5 14395 17 19 11 7 5 5 N N N N N N C14orf142 high in NP −3.5 0.002893925 −2.5 14396 25 17 13 5 8 5 N N N N N N TNFAIP1 high in NP −2.7 0.002881583 −2.5 14397 101 161 157 65 59 45 N N N N N N C9orf116 high in NP −10.6 0.002856898 −2.5 14398 21 13 2 1 1 1 N N N N N N UBXN1 high in NP −2.9 0.002823985 −2.5 14399 540 617 640 213 181 269 N N N N N N ZNF232 high in NP −9.7 0.002802729 −2.6 14400 8 16 12 3 3 3 N N N N N N MTA1 high in NP −5.4 0.002774616 −2.6 14401 316 626 324 58 124 99 N N N N N N CONK high in NP −2.9 0.002762274 −2.6 14402 166 219 247 96 85 80 N N N N N N C1orf35 high in NP −4.0 0.002725247 −2.6 14403 219 164 302 72 64 67 N N N N N N ALKBH7 high in NP −5.7 0.002719076 −2.6 14404 477 326 709 64 72 142 N N N N N N BATF high in NP −3.5 0.002712905 −2.6 14405 546 636 839 154 264 181 N N N N N N MRPS30 high in NP −3.0 0.002695077 −2.6 14406 59 85 51 21 23 30 N N N N N N ZNF581 high in NP −2.8 0.002653936 −2.6 14407 79 87 94 24 34 34 N N N N N N ACTR10 high in NP −2.3 0.002647765 −2.6 14408 54 45 38 20 22 24 N N N N N N SPINT1 high in NP −3.7 0.002623766 −2.6 14409 1031 1587 914 438 315 329 N N N N N N SEMA4B high in NP −3.8 0.002617595 −2.6 14410 1142 1871 2192 522 527 333 N N N N N N PBX2 high in NP −2.9 0.002599081 −2.6 14411 326 478 486 193 148 170 N N N N N N STARD10 high in NP −3.9 0.002579882 −2.6 14412 40 29 43 11 12 8 N N N N N N HYAL2 high in NP −7.0 0.002523656 −2.6 14413 26 75 58 12 13 10 N N N N N N PREB high in NP −5.6 0.002512685 −2.6 14414 65 202 116 29 21 24 N N N N N N EFEMP2 high in NP −3.5 0.002506514 −2.6 14415 144 139 203 44 44 57 N N N N N N SUSD3 high in NP −18.3 0.002500343 −2.6 14416 23 164 91 3 6 3 N N N N N N TEX10 high in NP −3.4 0.002494172 −2.6 14417 107 161 143 29 49 44 N N N N N N DCTN3 high in NP −4.8 0.002466059 −2.6 14418 115 212 218 27 46 55 N N N N N N CAPNS1 high in NP −5.1 0.002459888 −2.6 14419 1544 1674 1414 315 636 350 N N N N N N C10orf116 high in NP −3.5 0.002450288 −2.6 14420 316 558 502 155 146 161 N N N N N N CBX8 high in NP −6.0 0.002437946 −2.6 14421 21 25 37 9 5 5 P P N N P N POP5 high in NP −4.6 0.002405719 −2.6 14422 27 16 11 5 6 3 N N N N N N ELF1 high in NP −8.0 0.002399547 −2.6 14423 320 470 152 32 37 72 N N N N N N PLEKHG3 high in NP −3.5 0.002387205 −2.6 14424 251 208 224 61 93 63 N N N N N N EXOSC5 high in NP −4.5 0.002365949 −2.6 14425 46 65 75 14 11 19 N N N N N N BAI2 high in NP −3.6 0.002359778 −2.6 14426 60 54 34 17 19 19 N N N N N N SLC35B2 high in NP −5.1 0.002319323 −2.6 14427 82 176 102 17 35 24 N N N N N N TSTD1 high in NP −3.1 0.00230698 −2.6 14428 206 303 218 77 106 70 NA NA N N N N DPM2 high in NP −4.9 0.002287095 −2.6 14429 171 337 255 82 59 40 N N N N N N CCDC104 high in NP −3.2 0.002274753 −2.6 14430 51 49 29 13 14 15 N N N N N N FBX034 high in NP −2.3 0.002254183 −2.6 14431 32 46 33 15 15 14 N N N N P N ELMO2 high in NP −2.5 0.002229498 −2.7 14432 31 36 35 14 12 15 N N N N N N RPL13 high in NP −4.2 0.002223327 −2.7 14433 17982 15100 16762 3263 4470 6736 N N N N N N TMED3 high in NP −2.6 0.002192471 −2.7 14434 264 309 229 119 99 104 N N N N N N ZFYVE28 high in NP −3.1 0.002162301 −2.7 14435 21 33 39 9 9 9 P P N N N N DEGS2 high in NP −4.0 0.002143788 −2.7 14436 58 40 42 13 14 10 N N N N N N C19orf43 high in NP −3.2 0.002137617 −2.7 14437 1084 1722 1336 378 465 512 N N N N N N PXMP2 high in NP −6.1 0.00208619 −2.7 14438 8 12 8 3 3 3 N N N N N N RPLP2 high in NP −5.0 0.002080019 −2.7 14439 18281 18281 12128 2072 4166 4308 N N N N N N UBE2A high in NP −2.8 0.002073848 −2.7 14440 32 51 37 16 19 16 N N N N N N CHRNE high in NP −4.5 0.002067677 −2.7 14441 45 46 23 8 8 9 N N N N N N EDF1 high in NP −2.7 0.002016251 −2.7 14442 542 762 669 231 286 243 N N N N N N CHMP2B high in NP −6.9 0.001985395 −2.7 14443 148 101 50 18 18 23 N N N N N N DDX11 high in NP −7.1 0.001974424 −2.7 14444 25 25 20 4 9 5 N N N N N N C16orf89 high in NP −5.9 0.001964824 −2.7 14445 25 55 52 5 10 5 N N N N N N UROD high in NP −4.8 0.001958653 −2.7 14446 60 86 99 16 29 19 N N N N N N LOC728448 high in NP −4.2 0.001946311 −2.7 14447 NA NA NA NA NA NA N N N N N N NPDC1 high in NP −3.7 0.00194014 −2.7 14448 1125 967 884 182 276 334 N N N N N N MIER2 high in NP −5.6 0.001933969 −2.7 14449 45 99 95 13 19 22 N N N N N N MTX1 high in NP −4.8 0.001927798 −2.7 14450 230 458 288 83 98 55 N N N N N N CBLC high in NP −3.8 0.001915455 −2.7 14451 84 88 66 11 21 24 N N N N N N RPL10 high in NP −4.4 0.001898999 −2.7 14452 31854 26541 23996 5360 8922 9492 N N N N N N LOC389033 high in NP −10.6 0.001892828 −2.7 14453 17 13 52 1 4 1 NA NA N N N N NCRNA00116 high in NP −5.2 0.001880485 −2.7 14454 26 60 47 10 9 6 NA NA N N N N CTBS high in NP −3.0 0.001874314 −2.7 14455 87 106 112 40 32 35 N N N N N N KIF7 high in NP −7.2 0.001845516 −2.7 14456 21 16 15 9 9 12 N N N N N N SRP14 high in NP −4.3 0.001839344 −2.7 14457 120 98 81 23 33 16 N N N N N N TRPC4AP high in NP −3.8 0.001827002 −2.7 14458 756 1103 1224 240 355 300 N N N N N N SLC22A18 high in NP −5.4 0.00181466 −2.7 14459 236 135 233 33 53 31 N N N N N N TACSTD2 high in NP −4.2 0.001792718 −2.7 14460 4291 4010 2521 1034 1038 1017 N N N N N N RAB40B high in NP −5.1 0.001786547 −2.7 14461 86 52 71 16 23 14 N N N N N N TRIM52 high in NP −4.5 0.001725521 −2.8 14462 372 861 366 97 108 131 N N N N N N ARVCF high in NP −5.4 0.00171935 −2.8 14463 58 133 102 16 18 23 N N N N N N C6orf57 high in NP −4.1 0.001677523 −2.8 14464 6 3 6 1 1 1 N N N N N N TFF3 high in NP −40.6 0.001626097 −2.8 14465 1232 977 583 28 126 11 N N N N N N TSSC4 high in NP −4.7 0.001582213 −2.8 14466 111 143 179 26 28 45 P N N N N N WBP1 high in NP −3.4 0.001569871 −2.8 14467 200 219 277 70 89 84 N N N N N N ZAP70 high in NP −6.0 0.0015541 −2.8 14468 10 11 11 6 6 6 N N N N N N ZNF669 high in NP −7.8 0.001547929 −2.8 14469 40 106 78 15 10 8 N N N N N N AP1AR high in NP −3.4 0.001514331 −2.8 14470 43 60 38 16 21 15 NA NA N N N N PPP10A high in NP −4.5 0.001501988 −2.8 14471 74 123 93 32 20 23 N N N N N N OR2H1 high in NP −2.7 0.001474561 −2.8 14472 10 6 5 2 2 2 N N N N N N VCL high in NP −6.9 0.00146839 −2.8 14473 1766 2370 967 184 318 296 N N N N N N KIAA1324 high in NP −4.9 0.001456048 −2.8 14474 1354 1401 799 285 319 311 N N N N N N MRPS11 high in NP −13.0 0.001449877 −2.8 14475 16 49 41 4 4 7 N N N N N N SERPINA11 high in NP −19.8 0.001443705 −2.8 14476 52 18 97 2 5 2 N N N N N N ACTG1 high in NP −5.8 0.001437534 −2.8 14477 22394 28860 12299 3092 3700 5753 N N N N P N C6orf59 high in NP −3.7 0.001431363 −2.8 14478 8 8 6 3 3 3 NA NA N N N N B4GALNT4 high in NP −4.4 0.001410107 −2.9 14479 559 639 1079 153 165 196 N N N N N N C1orf159 high in NP −5.0 0.001395022 −2.9 14480 147 243 254 50 63 34 N N N N N N ARHGEF7 high in NP −5.3 0.001346338 −2.9 14481 186 302 267 37 66 68 P P N N N N HSP90AB1 high in NP −7.9 0.001271599 −2.9 14482 5431 11454 7412 517 922 1471 N N N N N N HES4 high in NP −4.6 0.001259257 −2.9 14483 1408 1675 3319 377 448 448 N N N N N N C12orf70 high in NP −8.3 0.001243486 −2.9 14484 14 17 25 2 2 5 NA NA N N N N EIF3G high in NP −4.9 0.001237315 −2.9 14485 350 605 524 84 128 140 N N N N N N PODXL2 high in NP −8.7 0.001224973 −2.9 14486 159 94 211 21 27 17 N N N N N N EIF6 high in NP −16.5 0.001218801 −2.9 14487 388 2109 1121 84 106 83 N N N N N N CDK20 high in NP −2.9 0.001206459 −2.9 14488 17 26 27 6 6 6 NA NA N N N N ZNF467 high in NP −8.9 0.001200288 −2.9 14489 39 55 46 12 4 4 N N N N N N HPX high in NP −6.7 0.001187946 −2.9 14490 492 500 549 123 87 39 N N N N N N ENY2 high in NP −8.7 0.001159833 −2.9 14491 27 24 7 2 2 2 N N N N N N FPGS high in NP −3.0 0.001093321 −3.0 14492 115 171 150 49 51 50 N N N N N N GCAT high in NP −2.6 0.001063837 −3.0 14493 15 14 12 6 6 6 N N N N N N ZNF783 high in NP −2.7 0.001057666 −3.0 14494 NA NA NA NA NA NA N N N N N N NCRNA00173 high in NP 5.9 0.001051495 −3.0 14495 23 14 25 2 2 6 NA NA N N N N TRAP1 high in NP −3.9 0.001045324 −3.0 14496 456 461 433 88 152 124 N N N N N N ABCA11P high in NP −3.1 0.001023382 −3.0 14497 7 5 3 2 2 2 N N N N N N AGR3 high in NP −13.3 0.001004868 −3.0 14498 179 173 85 5 22 15 N N N N N N PGLS high in NP −6.2 0.000992526 −3.0 14499 322 469 846 91 81 65 N N N N N N KRT86 high in NP −4.2 0.000967841 −3.0 14500 20 18 19 5 3 6 N N N N N N REEP5 high in NP −7.8 0.000939728 −3.0 14501 221 563 416 81 70 72 N N N N N N POMP high in NP −4.5 0.000921215 −3.0 14502 1115 1875 1124 285 374 271 N N N N N N RHOA high in NP −3.3 0.000899959 −3.0 14503 3764 4685 3685 1024 1334 1215 N N N N N N TNFRSF14 high in NP −4.3 0.000893788 −3.0 14504 170 165 207 38 43 59 N N N P N N CYP4F12 high in NP −3.1 0.000864646 −3.1 14505 7 5 4 2 2 2 N N N N N N GOLGA6L10 high in NP −3.1 0.000864646 −3.1 14506 7 4 3 2 2 2 NA NA N N N N TMSB15A high in NP −5.8 0.000792992 −3.1 14507 22 7 6 2 2 2 NA NA N N N N SH3GL1 high in NP −3.7 0.000777222 −3.1 14508 606 584 579 132 207 168 N N N N N N SELENBP1 high in NP −9.0 0.000764879 −3.1 14509 387 258 336 30 45 69 N N N N N N ZNF204P high in NP −2.9 0.000758708 −3.1 14510 24 30 23 12 12 12 NA NA N N N N LASP1 high in NP −6.8 0.000752537 −3.1 14511 184 316 138 38 34 35 N N N N N N PVRL4 high in NP −5.8 0.000692883 −3.2 14512 658 923 475 133 150 144 N N N N N N UBR4 high in NP −3.3 0.000686711 −3.2 14513 753 915 834 312 360 283 N N N N N N MARCKSL1 high in NP −6.7 0.000674369 −3.2 14514 964 1732 1447 188 222 327 N N N N N N TOMM34 high in NP −5.6 0.000655856 −3.2 14515 105 185 121 20 24 35 N N N N N N LRGUK high in NP −6.0 0.000640771 −3.2 14516 20 19 17 4 7 4 N N N N N N AZGP1 high in NP −1.4.0 0.000628428 −3.2 14517 1365 4611 1039 124 169 109 N N N N N N TMEM199 high in NP −4.2 0.0006154 −3.2 14518 17 27 16 4 4 4 N N N N N N NUDT16L1 high in NP −4.2 0.000592087 −3.2 14519 13 13 15 5 5 5 N N N N N N C19orf48 high in NP −8.2 0.000579745 −3.2 14520 477 437 597 58 119 74 N N N N N N NDUFS3 high in NP −4.4 0.000573574 −3.2 14521 191 213 140 34 42 52 N N N N N N C2orf63 high in NP −3.7 0.000558489 −3.3 14522 15 8 9 6 6 6 N N N N N N C17orf106 high in NP −5.6 0.000545461 −3.3 14523 47 42 33 6 9 4 NA NA N N N N LILRB3 high in NP −7.5 0.000533118 −3.3 14524 96 183 121 14 27 23 N N N N N N CCDC74A high in NP −20.5 0.000520776 −3.3 14525 13 28 44 1 1 1 N N N N N N RAB11B high in NP −5.6 0.000509805 −3.3 14526 324 675 345 85 74 77 N N N N N N DDX41 high in NP −4.1 0.000503634 −3.3 14527 218 326 211 63 71 66 N N N N N N JUP high in NP −6.6 0.000497463 −3.3 14528 3946 6065 8196 690 985 968 N N N N N N C11orf10 high in NP −6.9 0.000491292 −3.3 14529 840 1016 546 98 122 161 N N N N N N C19orf10 high in NP −6.7 0.000485121 −3.3 14530 493 565 372 73 114 71 N N N N N N ATHL1 high in NP −14.5 0.00047895 −3.3 14531 1481 2074 772 89 177 112 P N N N N N SCAND1 high in NP −9.1 0.000472778 −3.3 14532 220 354 524 49 42 37 N N N N N P LOC440957 high in NP −3.3 0.000448094 −3.3 14533 99 105 106 26 31 30 N N N N N N NDUFB4 high in NP −13.0 0.000428209 −3.4 14534 194 397 146 13 26 20 N N N N N N C7orf50 high in NP −31.8 0.000409696 −3.4 14535 39 164 120 4 4 4 N N N N N N ARHGEF10L high in NP −6.0 0.000397353 −3.4 14536 540 592 751 110 133 149 N N N N N N FUS high in NP −7.2 0.00037884 −3.4 14537 426 705 448 84 101 113 N N N N N N COX8A high in NP −7.9 0.000360326 −3.4 14538 792 1217 597 93 134 131 N N N N N N HMGCL high in NP −7.3 0.000354155 −3.5 14539 23 31 24 3 6 3 N N N N N N RPL10A high in NP −9.2 0.000347984 −3.5 14540 25349 23535 33127 2343 4115 4882 N N N N N N MGAT3 high in NP −4.6 0.000341813 −3.5 14541 18 21 13 6 6 6 N N N N N N LGMN high in NP −5.9 0.000328785 −3.5 14542 161 256 173 39 33 45 N N N N N N PRINS high in NP −6.4 0.0003137 −3.5 14543 40 69 52 10 8 11 N N N N N N RAB32 high in NP −4.7 0.000301358 −3.5 14544 110 113 123 25 32 30 N N N N N N FUZ high in NP −7.0 0.000295187 −3.5 14545 41 69 53 10 11 9 N N N N N N GOLGA6L1 high in NP −5.3 0.000282844 −3.5 14546 9 3 7 1 1 1 NA NA N N N N FAM150B high in NP −7.2 0.000276673 −3.6 14547 15 10 6 3 3 3 N P N N N N SYTL1 high in NP −7.0 0.000251988 −3.6 14548 111 109 177 15 20 19 N N N N N N PIN1 high in NP −6.6 0.000239646 −3.6 14549 117 178 176 28 20 28 N N N N N N MRPL54 high in NP −8.6 0.000217704 −3.7 14550 134 141 158 11 24 16 N N N N N N EGR4 high in NP −5.3 0.000205362 −3.7 14551 11 5 7 2 2 2 N P N N N N PTPRS high in NP −7.5 0.000199191 −3.7 14552 121 150 143 38 42 32 P P N N N N C5orf38 high in NP −16.5 0.00019302 −3.7 14553 33 22 42 4 2 2 N N N N N P TMSB10 high in NP −8.4 0.000179992 −3.7 14554 2539 4007 2574 309 483 360 N N N N N N TFF1 high in NP −21.3 0.000155307 −3.8 14555 3263 4094 1861 148 252 106 N N N N N N CHCHD5 high in NP −7.7 0.000134051 −3.9 14556 158 154 220 20 27 22 N N N N N N RNF126P1 high in NP −8.9 0.00012788 −3.9 14557 294 229 327 38 39 38 N N N N N N MRPL24 high in NP −9.5 0.000114166 −3.9 14558 159 146 101 14 16 13 N N N N N N ITIH4 high in NP −7.6 9.29E−05 −4.0 14559 44 52 48 11 9 9 N N N N N N LILRA5 high in NP −7.1 8.67E−05 −4.1 14560 19 21 20 3 3 3 P N N N N N PVRL2 high in NP −18.3 8.06E−05 −4.1 14561 1422 2284 2051 162 145 146 N N N N N N PRDM1 high in P 15.2 0.000107995 4.0 1 46 45 48 694 415 493 P N N N N N ANXA5 high in P 6.6 0.000140222 3.9 2 71 62 74 387 395 315 N N N N N N EDNRB high in P 86.1 0.000161478 3.8 3 25 24 36 1531 659 374 P N N N N N OGN high in P 6.2 0.000167649 3.8 4 6 6 6 16 14 15 N N N N N N CACNA1G high in P 22.8 0.000173821 3.8 5 15 15 18 141 73 124 P P N N N N HSD11B1 high in P 8.7 0.000211533 3.7 6 119 132 173 1340 832 841 N N N N N N CCT2 high in P 6.5 0.000223875 3.6 7 2173 2572 3724 15795 16912 15199 N N N N N N SRGAP2 high in P 7.9 0.000233475 3.6 8 39 59 57 422 283 213 N N N N N N PSCA high in P 5.4 0.000245817 3.6 9 16 20 15 87 96 66 N N N N N N USP45 high in P 4.4 0.000289015 3.5 10 48 63 50 207 159 171 N N N N N N PGS1 high in P 6.9 0.000307529 3.5 11 109 112 157 826 763 555 N N N N N N INPP5D high in P 7.9 0.000366498 3.4 12 14 12 18 77 83 102 N N N N N N BCAM high in P 13.8 0.000372669 3.4 13 246 159 356 3133 3572 1650 N N N N N N C15orf61 high in P 4.6 0.000385011 3.4 14 109 91 84 337 395 371 NA NA N N N N FST high in P 39.9 0.000391182 3.4 15 7 34 15 391 270 602 N N N N N N SLC25A1 high in P 5.3 0.000403524 3.4 16 247 259 341 1410 1214 1092 N N N N N N TSG101 high in P 5.1 0.000415867 3.4 17 616 747 780 4713 3568 2757 N N N N N N MIIP high in P 7.2 0.000422038 3.4 18 51 32 33 294 274 169 NA NA N N N N RPL9 high in P 5.1 0.00043438 3.4 19 17882 12321 16131 64070 57350 57363 N N N N N N PUS7L high in P 7.4 0.000466607 3.3 20 7 14 13 63 79 50 N N N N N N RPL23P8 high in P 4.6 0.000526947 3.3 21 6 1 2 12 12 14 NA NA N N N N ID3 high in P 5.6 0.00053929 3.3 22 75 78 90 490 293 321 P N N N N N SOX11 high in P 5.7 0.000585916 3.2 23 16 29 21 86 100 64 P N N N N N NRBP1 high in P 4.6 0.0006346 3.2 24 732 563 517 2513 2431 2151 N N N N N N NUDT16 high in P 4.0 0.000662027 3.2 25 25 35 31 121 104 78 N N N N N N REPIN1 high in P 5.2 0.000668198 3.2 26 508 618 685 4331 2842 2106 N N N N N N KIAA1324L high in P 4.0 0.00068054 3.2 27 18 20 17 50 58 56 N N N N N N NFIC high in P 6.1 0.000707968 3.1 28 494 398 427 3122 2437 1529 N N N N N N TLX3 high in P 5.0 0.000719624 3.1 29 2 2 2 24 14 18 P P N N N N LOX high in P 9.9 0.000725795 3.1 30 170 79 150 1540 941 934 N N N N N N ZNF425 high in P 3.7 0.000736766 3.1 31 90 103 117 351 314 287 N N N N N N LOC387763 high in P 22.3 0.000742937 3.1 32 NA NA NA NA NA NA NA NA N N N N XRCC6 high in P 6.3 0.00077105 3.1 33 3799 4173 6237 24188 27428 17331 N N N N N N SLC17A9 high in P 4.8 0.000783393 3.1 34 9 11 13 39 35 55 NA NA N N N N SP4 high in P 6.5 0.000799163 3.1 35 19 27 16 112 69 77 N N N N P N SCN4A high in P 10.5 0.000814248 3.1 36 20 21 26 128 71 72 N N N N N N CBR3 high in P 5.5 0.000823848 3.1 37 10 12 11 63 98 45 N N N N N N ERLIN1 high in P 7.6 0.000830019 3.1 38 199 264 430 1377 1691 1679 N N N N N N TULP2 high in P 9.5 0.00083619 3.1 39 4 4 4 13 16 51 P N N N N N TACC1 high in P 8.9 0.000842361 3.1 40 52 60 57 471 330 190 N N N N N N PJA1 high in P 5.9 0.000848533 3.1 41 71 47 91 342 349 299 N N N N N N CSN1S1 high in P 42.7 0.000873903 3.1 42 4 4 5 109 140 1191 N N N N N N TIPRL high in P 3.1 0.000887617 3.1 43 129 145 149 453 378 337 N N N N N N ZBTB7B high in P 3.4 0.00090613 3.0 44 399 508 579 1511 1545 1387 N N N N N N RMND5B high in P 8.5 0.000927386 3.0 45 101 92 189 831 735 562 N N N N N N PCMT1 high in P 4.9 0.000933557 3.0 46 549 452 574 2725 2900 1623 N N N N N N C6orf41 high in P 5.4 0.00096167 3.0 47 14 28 15 86 92 105 NA NA N N N N ITPRIP high in P 3.6 0.000974013 3.0 48 20 22 19 45 57 51 N N N N N N MAP4K4 high in P 2.8 0.000980184 3.0 49 305 438 392 1031 928 991 N N N N N N DSG2 high in P 5.2 0.000986355 3.0 50 1023 1043 740 4373 3649 5812 N N N N N N DUOX2 high in P 10.2 0.000998697 3.0 51 7 10 9 86 56 30 P P N N N N FLJ39653 high in P 5.0 0.001011039 3.0 52 10 11 13 32 33 43 NA NA N N N N ANKRD40 high in P 4.2 0.001017211 3.0 53 288 335 220 985 1207 881 N N N N N N MRPL32 high in P 3.1 0.001039152 3.0 54 468 522 394 1193 1355 1205 N N N N N N KCNK3 high in P 6.7 0.001070008 3.0 55 9 10 11 45 27 28 P P N N N N RARRES2 high in P 6.9 0.001076179 3.0 56 2 6 3 21 25 30 N N N N N N DIAPH3 high in P 2.7 0.00108715 3.0 57 4 8 8 21 22 20 N N N N N N DNM1L high in P 3.1 0.001099493 3.0 58 191 197 160 488 500 484 N N N N N N HNRNPU high in P 4.1 0.001114578 3.0 59 1042 932 631 3689 3576 4205 N N N N N N ASF1A high in P 6.5 0.001127606 2.9 60 57 75 88 481 415 225 N N N N N N COX18 high in P 11.2 0.001133777 2.9 61 26 38 31 388 285 115 N N N N N N SNAI3 high in P 10.8 0.001148862 2.9 62 3 3 7 30 30 34 P P N N N N PCY0X1 high in P 3.2 0.001166004 2.9 63 45 63 52 187 129 129 N N N N N N CXCL17 high in P 17.6 0.001172175 2.9 64 46 98 143 2147 662 720 N N N N N N LMAN2L high in P 17.4 0.001194117 2.9 65 54 63 192 771 799 706 N N N N N N METTL11A high in P 3.3 0.00121263 2.9 66 167 180 147 615 475 433 N N N N N N MTERFD2 high in P 5.4 0.001231144 2.9 67 21 58 35 226 148 143 N N N N N N NHEJ1 high in P 4.5 0.001253086 2.9 68 98 98 143 344 387 377 N N N N N N AKR1E2 high in P 2.8 0.001265428 2.9 69 4 5 5 12 11 12 NA NA N N N N LAMA4 high in P 13.6 0.00127777 2.9 70 50 49 76 767 436 214 N N N N N N PARG high in P 2.6 0.001292855 2.9 71 43 58 50 122 115 135 N N N N N N C8orf33 high in P 3.8 0.001299026 2.9 72 163 130 141 552 393 524 N N N N N N LDB2 high in P 3.3 0.001305197 2.9 73 14 15 12 33 27 30 N P N N N N SLC43A1 high in P 5.5 0.001333996 2.9 74 19 16 14 90 73 42 N N N N N N MYLK high in P 14.3 0.001340167 2.9 75 70 76 52 327 241 908 N N N N N N RGS5 high in P 5.6 0.00135251 2.9 76 17 18 17 81 45 49 N N N N N N TGFB2 high in P 5.3 0.001367595 2.9 77 172 101 165 536 674 752 N N N N N N SIN3A high in P 3.8 0.001373766 2.9 78 304 385 489 1609 1068 1496 N N N N N N SHF high in P 5.4 0.001379937 2.9 79 22 41 48 202 164 133 N N N N N N NPTN high in P 2.8 0.001416278 2.8 80 355 352 299 849 819 948 N N N N N N RACGAP1 high in P 4.4 0.001462219 2.8 81 36 16 29 127 118 98 N N N N N N C18orf25 high in P 4.5 0.001489646 2.8 82 115 87 76 327 265 387 N N N N N N LOC285375 high in P 5.8 0.001495817 2.8 83 3 3 3 20 11 9 NA NA N N N N TIE1 high in P 15.3 0.00150816 2.8 84 13 27 36 438 193 112 N N N N N N B3GAT1 high in P 23.6 0.001532844 2.8 85 9 16 13 50 208 258 P N N N N N SLC1A5 high in P 14.8 0.001560272 2.8 86 617 1024 2753 16550 15441 8601 N N N N N N AES high in P 5.4 0.001576042 2.8 87 2329 3777 5620 18818 16607 13627 N N N N N N NHEDC2 high in P 3.1 0.001588385 2.8 88 65 51 59 155 164 159 N N N N N N SYNPO high in P 2.9 0.001594556 2.8 89 28 61 51 117 93 113 N N N N N N ZFAND2B high in P 3.0 0.001600727 2.8 90 143 136 116 324 333 420 N N N N N N FOXO1 high in P 3.5 0.001606898 2.8 91 135 216 182 577 413 593 N N N N N N LXN high in P 9.3 0.001619926 2.8 92 19 18 7 161 64 79 N N N N N N RRAGD high in P 4.4 0.001632268 2.8 93 72 136 74 305 260 331 N N N N N N C10orf118 high in P 2.9 0.001638439 2.8 94 61 58 67 164 152 132 N N N N N N PI4K2A high in P 5.9 0.00164941 2.8 95 235 325 516 1933 1635 1287 N N N N N N SLC43A2 high in P 7.7 0.001655581 2.8 96 61 197 107 828 647 464 N N N N N N WDR45 high in P 3.7 0.001661753 2.8 97 312 482 442 1788 1403 1079 P N N N N N PLEKHF1 high in P 4.0 0.001671352 2.8 98 358 228 264 951 1076 940 N N N N N N SOX10 high in P 5.8 0.001683694 2.8 99 436 273 224 1729 1345 1187 N N N N N N IL17RA high in P 3.3 0.001689866 2.8 100 51 54 53 147 168 123 N N N N N N C15orf48 high in P 17.0 0.001696037 2.8 101 142 77 17 892 949 638 N N N N N N GRPEL1 high in P 2.4 0.001774205 2.8 102 279 343 361 702 790 759 N N N N N N MLX high in P 3.5 0.001780376 2.7 103 251 302 368 1185 896 758 N N N N N N SOBP high in P 7.2 0.001798889 2.7 104 27 30 27 51 55 110 P P N N N N SIX5 high in P 4.7 0.00180506 2.7 105 105 75 57 330 299 234 N N N N N N PRDX6 high in P 2.7 0.001820831 2.7 106 1138 1219 1136 3911 2960 2647 N N N N N N MID1IP1 high in P 2.7 0.001833173 2.7 107 107 135 97 262 239 268 N N N N N N LAMC3 high in P 4.9 0.001851687 2.7 108 17 17 18 48 35 40 P P N N N N ZNF507 high in P 3.2 0.001857858 2.7 109 31 33 27 83 72 77 N N N N N N MRPS18C high in P 4.1 0.001886657 2.7 110 24 25 35 115 87 88 N N N N N N ZNF384 high in P 4.2 0.001921626 2.7 111 277 269 439 1074 1177 1024 N N N N N N SRPX high in P 10.8 0.001952482 2.7 112 9 9 9 39 22 14 P N N N N N AIPL1 high in P 5.5 0.001991566 2.7 113 18 8 15 74 97 45 N N N N N N VNN3 high in P 8.8 0.001997737 2.7 114 23 131 81 838 533 516 N N N N N N KIAA0649 high in P 2.8 0.002003908 2.7 115 88 85 77 178 194 188 N N N N N N APPBP2 high in P 4.3 0.00201008 2.7 116 77 65 59 195 193 246 N N N N N N FERMT1 high in P 14.4 0.002022422 2.7 117 15 8 9 108 219 44 P N N N N N RNH1 high in P 3.5 0.002028593 2.7 118 927 1125 1491 5032 4942 3313 N N N N N N PIK3R1 high in P 5.5 0.002034764 2.7 119 70 203 128 680 508 408 N N N N N N CYB5R2 high in P 8.0 0.002040935 2.7 120 257 291 707 2627 1871 2182 N N N N N N FBX027 high in P 4.4 0.002061506 2.7 121 66 49 61 283 164 189 N N N N N N G10orf90 high in P 2.6 0.002092361 2.7 122 11 10 10 30 24 29 N N N N N N SLC29A1 high in P 3.2 0.002131445 2.7 123 392 274 347 1129 1020 918 N N N N N N LRTOMT high in P 3.9 0.002149959 2.7 124 22 16 18 46 48 44 NA NA N N N N TCHP high in P 5.5 0.00215613 2.7 125 77 63 132 318 395 336 N N N N N N ADI1 high in P 3.0 0.002173272 2.7 126 51 45 52 167 114 126 N N N N N N ELTD1 high in P 10.7 0.002179443 2.7 127 11 58 27 393 174 164 N N N N N N PDE4C high in P 3.4 0.002198642 2.7 128 25 30 38 84 71 94 P P N N N N UIMC1 high in P 3.0 0.002204813 2.7 129 52 53 37 109 114 139 N N N N P N IRX1 high in P 9.1 0.002210985 2.7 130 106 123 292 740 831 1192 P N N N N N ETV7 high in P 8.7 0.002217156 2.7 131 12 25 36 257 172 105 N N N N N N PSPH high in P 9.9 0.002235669 2.7 132 6 10 25 112 98 59 N N N N N N GFER high in P 3.9 0.00224184 2.6 133 70 78 103 362 246 210 N N N N P N KREMEN1 high in P 3.7 0.002248012 2.6 134 30 71 76 178 206 160 N N N N N N TTC32 high in P 4.7 0.002265154 2.6 135 53 26 27 157 160 102 N N N N N N NEDD4 high in P 3.9 0.002280924 2.6 136 17 25 33 72 68 81 N N N N N N CCND2 high in P 7.4 0.002293267 2.6 137 35 49 38 113 101 273 P P N N N N MESTIT1 high in P 5.5 0.002313151 2.6 138 62 19 56 241 280 230 N N N N N N TAF11 high in P 2.4 0.002332351 2.6 139 156 184 147 331 316 359 N N N N N N BRF1 high in P 3.5 0.002338522 2.6 140 186 128 177 436 530 537 N N N N N N HLA-B high in P 2.9 0.002348121 2.6 141 13384 16928 17858 43892 36932 30507 N N N N N N RUNX3 high in P 2.6 0.002381034 2.6 142 85 129 128 259 286 257 P P N N N N FMNL3 high in P 7.2 0.002393376 2.6 143 39 50 93 261 180 271 N N N N P N DAZAP2 high in P 4.2 0.002444117 2.6 144 2079 1741 880 8614 7088 6069 N N N N N N C14orf167 high in P 4.5 0.002479087 2.6 145 27 26 32 101 130 66 N N N N N N IL2RA high in P 4.1 0.002554512 2.6 146 130 164 239 640 563 485 N N N N N N ST6GALNAC5 high in P 3.4 0.00259291 2.6 147 14 8 11 27 40 35 N N N N N N SERPINB7 high in P 5.5 0.002605252 2.6 148 3 23 10 67 81 59 N N N N N N RBM27 high in P 2.9 0.002611423 2.6 149 49 108 72 241 250 162 N N N N N N KIAA1949 high in P 4.0 0.002641594 2.6 150 1155 1074 1666 4602 3992 7057 N N N N N N MMP3 high in P 9.8 0.002675878 2.6 151 20 30 29 327 133 66 N N N N N N RAB34 high in P 6.2 0.002688906 2.6 152 243 406 607 3242 2485 1335 N N N N N N SFRP4 high in P 5.5 0.002701248 2.6 153 16 18 18 61 29 44 P P N N N N HIRIP3 high in P 4.2 0.002731418 2.6 154 2 2 3 13 12 22 N N N N N N C15orf57 high in P 4.9 0.002737589 2.6 155 26 36 41 148 189 90 N N N N N N AHNAK2 high in P 5.3 0.00274376 2.6 156 38 54 85 189 174 211 N N N N N N SULT1B1 high in P 6.5 0.002768445 2.6 157 1 1 1 12 17 7 N N N N N N STEAP1 high in P 4.9 0.002780787 2.6 158 194 231 159 904 872 451 N N N N N N TSHZ3 high in P 2.9 0.002817814 2.6 159 23 27 21 42 46 39 P P N N N N UPF3B high in P 3.6 0.002830156 2.5 160 98 60 61 202 186 211 N N N N N N C17orf103 high in P 5.9 0.002841127 2.5 161 60 67 61 472 271 152 NA NA N N N N SS18L2 high in P 6.4 0.002863069 2.5 162 616 207 359 2156 2955 1519 N N N N N N C1R high in P 4.5 0.00286924 2.5 163 168 351 202 1261 756 643 N P N N N N CNRIP1 high in P 5.7 0.002875411 2.5 164 5 11 7 48 36 29 P P N N N N BTG3 high in P 3.7 0.002887754 2.5 165 28 55 47 157 110 109 N N N N N N IDO1 high in P 12.3 0.002927523 2.5 166 3 26 11 71 102 299 NA NA N N N N SHROOM2 high in P 3.4 0.003006377 2.5 167 34 42 30 169 102 84 N N N N N N LOC283174 high in P 5.8 0.003027633 2.5 168 12 13 13 28 55 59 N N N N N N KLF15 high in P 3.7 0.003055746 2.5 169 8 10 8 15 19 21 N N N N N N C9orf123 high in P 2.3 0.003077002 2.5 170 133 166 115 279 313 278 N N N N N N C2orf15 high in P 2.9 0.003143513 2.5 171 246 193 227 630 597 491 N N N N N N ATP8B2 high in P 6.7 0.003149685 2.5 172 27 53 29 107 89 174 N N N N N N PDPN high in P 4.2 0.003186711 2.5 173 10 13 10 28 20 31 P P N N N N HAX1 high in P 3.9 0.003192883 2.5 174 651 442 582 2015 2954 1440 N N N N N N BCL2L11 high in P 3.9 0.003214139 2.5 175 309 310 381 2689 1141 967 N N N N N N CD93 high in P 6.5 0.003223738 2.5 176 19 43 29 325 102 94 P P N N N N PIP4K2B high in P 2.7 0.003292992 2.5 177 32 39 35 79 59 76 N N N N N N TMOD1 high in P 7.0 0.003305335 2.5 178 18 33 45 116 307 105 N N N N N N UBFD1 high in P 2.9 0.003311506 2.5 179 85 75 96 252 217 188 N N N N N N PRRG1 high in P 2.8 0.003376646 2.5 180 55 68 82 153 140 156 N P N N N N HSPA12B high in P 27.6 0.003395845 2.5 181 9 9 20 102 86 45 N P N N N N FOXF2 high in P 10.6 0.003408187 2.5 182 6 7 6 54 14 34 P P N N P N IFITM3 high in P 4.0 0.003428758 2.5 183 254 400 456 1751 1303 886 N N N N N N NDUFV3 high in P 5.5 0.0034411 2.5 184 314 173 285 1581 1627 685 N N N N N N GZF1 high in P 5.6 0.003447271 2.5 185 38 50 89 169 212 220 N N N N N N ZNF3970S high in P 3.0 0.003459613 2.5 186 50 42 34 128 112 88 N N N N N N CXorf15 high in P 5.1 0.003500754 2.5 187 NA NA NA NA NA NA N N N N N N FAM110A high in P 3.1 0.00352201 2.5 188 87 141 93 241 258 290 N N P N N N SMYD4 high in P 2.6 0.003528182 2.5 189 74 77 92 179 165 203 N N N N N N C1orf51 high in P 6.8 0.003546009 2.5 190 77 24 109 580 331 447 N N N N N N POU3F1 high in P 3.8 0.00356658 2.4 191 20 13 17 31 35 48 P P N N N N SPARC high in P 3.8 0.003572751 2.4 192 36 43 37 141 74 92 N N N N N N DNAJC6 high in P 5.3 0.003578922 2.4 193 18 24 17 98 41 73 N N N N N N USH1G high in P 3.8 0.003591264 2.4 194 17 27 38 72 90 96 N P N N N N LHFP high in P 6.5 0.003624863 2.4 195 14 12 11 42 26 99 N N N N N N ITCH high in P 3.2 0.003631034 2.4 196 54 45 53 122 132 122 N N N N N N GLG1 high in P 2.7 0.003637205 2.4 197 485 430 578 1680 1304 1024 N N N N N N SMC4 high in P 2.5 0.003652976 2.4 198 23 31 24 49 53 67 N N N N N N ASAP3 high in P 5.7 0.003659147 2.4 199 18 15 16 112 40 65 N N N N N N CWF19L1 high in P 5.1 0.003665318 2.4 200 17 22 29 87 132 53 N N N N N N KRTAP3-2 high in P 5.8 0.003703716 2.4 201 1 1 1 8 8 4 N N N N N N RGMA high in P 2.8 0.003740058 2.4 202 96 136 88 265 302 203 N N N N N N EPR1 high in P 20.6 0.003770913 2.4 203 11 2 30 87 160 183 N N N N N N KLHL7 high in P 2.7 0.003857309 2.4 204 21 31 27 49 65 63 N N N N N N INPP5K high in P 2.9 0.003875823 2.4 205 47 105 75 222 192 159 N N N N N N ST6GALNAC4 high in P 6.2 0.003881994 2.4 206 85 110 187 972 634 332 N N N N N N PARD6G high in P 2.3 0.003894336 2.4 207 31 36 36 60 68 74 N N N N N N ZNF33A high in P 3.8 0.003932049 2.4 208 124 135 107 401 554 242 N N N N N N OR7E91P high in P 2.8 0.00393822 2.4 209 10 6 7 17 28 25 N N N N N N DDR2 high in P 5.2 0.003978675 2.4 210 29 16 21 142 87 51 N N N N N N NME2P1 high in P 4.7 0.004034901 2.4 211 14 5 6 55 44 23 N N N N N N OSTF1 high in P 3.6 0.004053415 2.4 212 157 268 223 1033 712 487 N N N N P N UBE2Q1 high in P 3.3 0.004079471 2.4 213 65 124 101 290 351 197 N N N N N N DBF4B high in P 2.7 0.004085642 2.4 214 580 408 479 1315 1108 1229 N N N N N N ARHGEF5L high in P 3.7 0.004137068 2.4 215 NA NA NA NA NA NA NA NA N N N N ACSL4 high in P 4.6 0.004152153 2.4 216 52 28 36 132 131 97 N N N N N N KLHL26 high in P 3.6 0.004171352 2.4 217 9 11 13 47 25 27 N N N N N N TSEN54 high in P 3.2 0.004177523 2.4 218 83 141 141 360 400 258 N N N N N N PARP10 high in P 4.8 0.004196037 2.4 219 227 106 314 967 966 833 N N N N N N MY010 high in P 2.2 0.004268033 2.4 220 311 349 327 710 700 619 N P N N N N ODAM high in P 4.5 0.004280376 2.4 221 2 2 2 22 7 13 N N N N N N CD58 high in P 2.8 0.004292718 2.4 222 33 26 26 70 63 77 N N N N N N INTS12 high in P 4.4 0.004320145 2.4 223 120 99 218 450 510 465 N N N N N N FBLN5 high in P 10.0 0.004364715 2.4 224 239 673 126 2555 1311 2097 N N N N N N TMEM106A high in P 3.0 0.004370886 2.4 225 30 34 47 91 96 87 N N N N N N OPLAH high in P 4.4 0.004392828 2.4 226 204 129 338 785 864 811 N N N N N N ANKRD45 high in P 3.6 0.004418884 2.4 227 11 14 17 43 46 33 P P N N N N SHE high in P 2.6 0.004449054 2.4 228 31 36 43 80 75 70 P P N N N N ERAL1 high in P 3.9 0.004461396 2.4 229 77 171 84 419 317 262 N N N N N N PLCB3 high in P 3.4 0.004509394 2.3 230 13 28 16 73 51 43 N N N N N N DNER high in P 9.3 0.004521736 2.3 231 12 9 34 78 110 241 P P N N N N LCC401127 high in P 3.0 0.004527907 2.3 232 21 25 28 78 65 51 NA NA N N N N EGFLAM high in P 3.5 0.004620474 2.3 233 24 18 18 43 45 35 P P N N N N GRID1 high in P 12.5 0.004666415 2.3 234 12 12 12 52 42 18 P P N N N N TRIM5 high in P 2.6 0.004685614 2.3 235 62 52 40 129 111 115 N N N N N N DGKE high in P 2.5 0.004733612 2.3 236 139 138 191 337 361 328 N N N N N N STEAP3 high in P 8.4 0.004739783 2.3 237 62 75 246 706 693 439 N N N N N N HOXC8 high in P 6.0 0.004772696 2.3 238 9 22 31 98 58 93 N P N N N N ADAMTS5 high in P 3.9 0.004788467 2.3 239 37 37 37 61 47 66 P P N N N N EYA2 high in P 3.6 0.004809723 2.3 240 208 118 261 765 664 549 N N N N N N PRPSAP2 high in P 3.4 0.004850864 2.3 241 125 152 188 760 384 405 N N N N N N CYGB high in P 4.9 0.004873491 2.3 242 24 22 36 185 89 69 N N N N N N PDGFRB high in P 9.8 0.00490709 2.3 243 28 31 39 192 68 68 N N N N N N SV2A high in P 3.7 0.004919432 2.3 244 16 19 24 48 35 64 N N N N N N C21orf91 high in P 7.0 0.004958516 2.3 245 34 154 50 315 313 400 N N N N N N PLIN2 high in P 4.6 0.004992115 2.3 246 57 127 107 526 326 218 NA NA N N N N SLC39A13 high in P 2.9 0.004998286 2.3 247 300 515 688 1366 1609 1361 N N N N N N YIPF4 high in P 2.5 0.005004457 2.3 248 88 106 52 182 210 199 N N N N N N PDE7B high in P 2.6 0.00502297 2.3 249 14 21 17 27 32 30 N N N N N N CD40 high in P 5.9 0.005029142 2.3 250 27 56 25 280 135 91 N N N N N N SETD8 high in P 6.4 0.005041484 2.3 251 433 353 1135 2298 2660 2636 N N N N N N BCAN high in P 4.4 0.005053826 2.3 252 52 27 77 215 158 191 N N N N N N TMEM204 high in P 11.3 0.00510251 2.3 253 10 11 32 156 90 67 N N N N N N RAB6C high in P 4.0 0.005114166 2.3 254 1 1 1 5 6 12 N N N N N N PIGP high in P 3.4 0.005129251 2.3 255 93 65 101 317 217 195 N N N N N N SHC1 high in P 3.0 0.005179992 2.3 256 54 108 71 218 173 149 N N N N N N FABP5 high in P 7.3 0.005186163 2.3 257 2 5 14 50 41 33 P P N N N N GOLGB1 high in P 2.5 0.005208105 2.3 258 243 272 223 621 468 572 N N N N N N MMP12 high in P 7.8 0.005256103 2.3 259 8 27 18 152 87 70 N N N N N N HUNK high in P 3.1 0.005282159 2.3 260 17 20 23 32 34 35 P N N N N N CFP high in P 3.9 0.00528833 2.3 261 11 12 19 45 40 45 P P N N N N CCNC high in P 2.7 0.005439866 2.3 262 62 61 61 159 140 100 N N N N N N SGK196 high in P 2.9 0.005446037 2.3 263 4 4 4 8 10 10 N N N N N N INHBA high in P 7.6 0.005500891 2.3 264 9 62 23 147 168 112 N N N N N N C17orf63 high in P 3.2 0.005513234 2.3 265 390 227 302 785 827 824 N N N N N N CHST9 high in P 3.4 0.005537918 2.3 266 17 13 20 45 39 44 N N N N N N LCLAT1 high in P 3.9 0.005566031 2.3 267 52 122 78 363 234 184 NA NA N N N N ADRB3 high in P 6.0 0.005613343 2.3 268 31 54 38 246 215 87 P P N N N N PSMB2 high in P 4.4 0.00566477 2.2 269 565 798 1053 4756 4023 1681 N N N N N N KIAA0562 high in P 5.6 0.005677798 2.2 270 81 159 313 816 609 619 N N N N N N LOC440944 high in P 3.6 0.005683969 2.2 271 112 72 113 243 236 352 NA NA N N N N FAM126A high in P 2.8 0.005696311 2.2 272 34 39 37 45 54 60 N N N N N N ESRP2 high in P 2.3 0.005734709 2.2 273 90 132 116 198 262 225 NA NA N N N N ATMIN high in P 2.7 0.005787507 2.2 274 66 132 94 276 222 183 N N N N N N PPP1R3F high in P 8.1 0.005793678 2.2 275 10 21 50 146 111 96 N N N N N N FADS6 high in P 4.3 0.005808763 2.2 276 5 7 7 16 27 18 P P N N N N COPS7B high in P 3.5 0.005814934 2.2 277 35 15 18 79 60 62 N N N N N N QRSL1 high in P 5.8 0.005821105 2.2 278 244 129 420 1330 1293 802 N N N N N N CIB2 high in P 5.6 0.005827276 2.2 279 87 27 109 512 406 237 N N N N N N C1orf74 high in P 3.5 0.005842361 2.2 280 5 7 5 11 22 18 N N N N N N WFDC5 high in P 16.8 0.005854704 2.2 281 1 5 31 96 235 94 N N N N N N FAM115A high in P 3.0 0.00588076 2.2 282 298 154 279 754 741 647 N N N N N N STK25 high in P 2.1 0.005895845 2.2 283 92 135 125 201 231 224 N N N N N N USP40 high in P 3.4 0.005928072 2.2 284 96 175 191 594 470 296 N N N N N N TMLHE high in P 3.5 0.005960299 2.2 285 21 20 40 80 91 70 N N N N N N CDKN2A high in P 3.9 0.00596647 2.2 286 41 45 32 129 157 69 P P N N N N OSGIN2 high in P 3.7 0.005977441 2.2 287 22 24 21 85 86 38 N N N N N N FGFR2 high in P 3.4 0.006028867 2.2 288 176 102 128 330 369 492 N N N N N N TXN high in P 3.1 0.006058352 2.2 289 20 10 12 29 35 33 N N N N N N MAP3K4 high in P 2.5 0.00610155 2.2 290 42 47 44 91 75 110 N N N N N N SIRPB2 high in P 4.1 0.006107721 2.2 291 57 26 89 262 207 200 N N N N N N NFE2L1 high in P 5.2 0.006113892 2.2 292 646 895 1046 6677 4367 1782 N N N N N N GPATCH2 high in P 3.9 0.006123491 2.2 293 154 86 85 248 404 350 N N N N N N LOC349196 high in P 2.4 0.006142691 2.2 294 40 48 44 95 73 99 NA NA N N N N MAST3 high in P 3.1 0.006249657 2.2 295 25 39 36 182 85 76 N N N N N N ZEB2 high in P 8.8 0.006255828 2.2 296 21 21 22 62 55 27 P P N N N N DRAM1 high in P 4.7 0.00630314 2.2 297 38 65 28 230 127 98 NA NA N N N N CTPS high in P 3.8 0.006329196 2.2 298 149 314 169 533 611 553 N N N N N N LOC84740 high in P 4.3 0.006340167 2.2 299 7 7 7 18 22 40 NA NA N N N N WDR27 high in P 3.8 0.006353195 2.2 300 17 17 29 98 50 74 N N N N P N C13orf34 high in P 3.6 0.006391594 2.2 301 5 15 9 39 29 29 N N N N N N ALKBH4 high in P 4.6 0.006397765 2.2 302 610 275 294 1588 1277 1025 N N N N N N C11orf57 high in P 2.6 0.006419707 2.2 303 41 63 32 110 108 88 N N N N N N IKZF2 high in P 3.8 0.006425878 2.2 304 31 41 24 72 81 56 N N N N N N ERMP1 high in P 10.9 0.006432049 2.2 305 35 42 75 704 376 110 N N N N N N CH25H high in P 4.2 0.006497874 2.2 306 3 3 5 9 13 22 P P N N N N CCL4 high in P 7.1 0.006514331 2.2 307 2 10 2 24 21 50 N N N N N N RPS11 high in P 5.1 0.006520502 2.2 308 43897 16111 19270 103882 103882 64055 N N N N N N DNAJC8 high in P 2.6 0.006526673 2.2 309 366 338 508 899 951 912 N N N N N N SSBP3 high in P 3.5 0.00653833 2.2 310 26 21 26 50 58 81 N N N N N N C17orf77 high in P 3.4 0.006579471 2.2 311 5 6 7 18 16 43 N P N N N N POLL high in P 2.8 0.006585642 2.2 312 134 88 105 261 243 277 N N N N N N RAB4A high in P 3.1 0.006597984 2.2 313 196 132 115 316 376 419 N N N N N N CEBPB high in P 2.5 0.006604155 2.2 314 6405 8486 5876 12334 14427 20157 N N N N N N C2orf60 high in P 2.6 0.006625411 2.2 315 32 50 57 127 118 79 N N N N N N FOXC2 high in P 5.4 0.00666381 2.2 316 4 15 28 73 131 69 P P N N N N GBGT1 high in P 2.6 0.006669981 2.2 317 25 19 21 59 59 40 N N N N N N NASP high in P 2.9 0.006700151 2.2 318 389 213 293 749 759 863 N N N N N N DDHD2 high in P 2.5 0.006706322 2.2 319 39 48 52 101 114 75 N N N N N N TBX2 high in P 8.8 0.006717293 2.2 320 20 29 12 158 48 70 P P N N N N UBQLNL high in P 4.2 0.006723464 2.2 321 2 2 2 7 13 7 N N N N N N TBC1D10A high in P 2.8 0.006729635 2.2 322 34 24 20 65 60 52 N N N N N N AIP high in P 3.3 0.006785176 2.2 323 6 18 15 42 51 30 N N N N N N CD34 high in P 5.7 0.006807117 2.2 324 15 19 23 191 74 43 P N N N N N DENND1A high in P 4.7 0.006846887 2.2 325 120 94 147 570 511 228 N N N N N N FAM3C high in P 2.5 0.006896256 2.2 326 22 47 49 84 107 101 N N N N N N UNC45A high in P 2.2 0.006902427 2.2 327 238 353 368 750 607 633 N N N N N N ADC high in P 8.2 0.006923683 2.2 328 22 45 114 206 265 427 N N N N N N CSF1 high in P 2.8 0.006938769 2.2 329 49 40 42 122 106 95 N N N N N N LSM11 high in P 2.7 0.006954539 2.2 330 3 4 4 9 13 9 N N N N N N ABHD3 high in P 4.0 0.006976481 2.2 331 6 6 12 33 27 28 N N N N N N LOC100170939 high in P 2.9 0.006982652 2.2 332 10 6 11 29 22 41 N N N N N N NSL1 high in P 2.4 0.007001851 2.2 333 43 54 50 73 98 75 N N N N N N RABL3 high in P 5.5 0.007029279 2.2 334 87 124 276 761 932 411 N N N N N N SULT2B1 high in P 4.0 0.00703545 2.2 335 84 48 95 342 254 174 N N N N N N HSPA1L high in P 5.0 0.007047106 2.2 336 9 5 12 28 24 51 N N N N N N LZTS1 high in P 3.3 0.007062877 2.2 337 23 18 25 37 46 59 P N N N P N ZNF331 high in P 3.0 0.007069048 2.2 338 48 33 40 102 77 122 N N N N N N NUFIP1 high in P 2.1 0.007075219 2.2 339 37 42 33 72 89 71 N N N N N N KCNH8 high in P 2.9 0.007141731 2.1 340 18 23 17 28 42 45 N N N N N N NRG1 high in P 5.4 0.007166415 2.1 341 28 51 66 89 183 231 P P N N N N DDX51 high in P 3.9 0.00724184 2.1 342 118 92 234 409 530 427 N N N N N P MSC high in P 11.3 0.007248012 2.1 343 6 7 9 77 24 22 P P N N N N TAF3 high in P 4.3 0.007306295 2.1 344 22 81 63 254 150 190 N N N N N N C11orf52 high in P 2.5 0.007370063 2.1 345 53 57 44 191 98 118 N N N N N N PLVAP high in P 4.8 0.007388577 2.1 346 17 21 23 89 49 33 N N N N N N RSAD1 high in P 2.4 0.007448231 2.1 347 9 14 10 20 26 20 N N N N N N RUNDC2C high in P 3.2 0.007507885 2.1 348 23 25 30 47 68 49 N N N N N N DEXI high in P 9.2 0.007524342 2.1 349 279 469 1501 3839 4137 2691 N N N N N N LOC93432 high in P 5.6 0.007571654 2.1 350 2 8 3 48 25 17 N N N N N N NFXL1 high in P 2.5 0.007596338 2.1 351 19 22 13 38 41 34 N N N N N N NOLC1 high in P 2.8 0.00760251 2.1 352 69 73 67 108 167 169 N N N N N N CBX7 high in P 2.5 0.00772319 2.1 353 44 65 44 162 101 99 N N N N N N POM121 high in P 2.6 0.007729361 2.1 354 30 24 29 60 87 51 N N N N N N NFYA high in P 2.4 0.007762959 2.1 355 303 264 399 614 679 798 N N N N N N LOC440896 high in P 3.5 0.007814386 2.1 356 33 15 24 48 82 94 N N N N N N ZNF619 high in P 4.5 0.007834956 2.1 357 NA NA NA NA NA NA N N N N N N GPATCH3 high in P 2.9 0.007895296 2.1 358 80 69 102 262 211 155 N N N N N N PAPL high in P 2.5 0.007901467 2.1 359 453 355 527 1294 1096 862 NA NA N N N N COMT high in P 4.1 0.007922038 2.1 360 19 45 65 149 150 88 N N N N N N SNTB2 high in P 2.5 0.007990606 2.1 361 143 150 186 291 287 366 N N N N P N PRRG2 high in P 4.7 0.008015291 2.1 362 67 72 169 445 313 256 N N N N N N MPPE1 high in P 3.4 0.008053003 2.1 363 54 90 96 235 331 146 N N N N N N MTMR9 high in P 2.1 0.008074945 2.1 364 25 53 53 105 85 80 N P N N N N C6orf145 high in P 5.1 0.008081116 2.1 365 902 752 2016 4967 3523 4878 N N N N N N WFDC6 high in P 6.2 0.008151056 2.1 366 1 1 1 17 4 9 N N N N N N COL4A3BP high in P 2.1 0.008157227 2.1 367 31 39 32 61 52 68 N N N N N N BOC high in P 5.4 0.008172998 2.1 368 60 44 67 149 124 354 N N N N N N AIDA high in P 3.4 0.008179169 2.1 369 42 104 90 288 185 181 N N N N N N UTP6 high in P 3.3 0.008204539 2.1 370 138 112 77 207 307 410 N N N N N N MAP1S high in P 4.3 0.008257337 2.1 371 1790 707 2481 8901 7833 5168 N N N N N N ANKRD49 high in P 3.0 0.008299849 2.1 372 12 24 11 32 59 61 N N N N N N LOC100133920 high in P 3.1 0.008413673 2.1 373 7 7 7 13 15 10 N N N N N N HPS6 high in P 3.1 0.008445214 2.1 374 79 79 43 209 194 121 N N N N N N HTR3B high in P 3.2 0.008451385 2.1 375 110 57 120 360 317 214 N N N N N N DHX8 high in P 3.0 0.008517211 2.1 376 172 194 328 753 763 456 N N N N N N MCM2 high in P 2.8 0.00852681 2.1 377 76 59 87 211 179 137 N N N N N N MNAT1 high in P 2.7 0.008532981 2.1 378 131 146 223 569 479 309 N N N N N N RAB36 high in P 2.5 0.008605664 2.1 379 25 20 19 41 47 33 N N N N N N GTF2B high in P 2.1 0.008611835 2.1 380 189 211 251 479 451 364 N N N N N N FANCB high in P 4.7 0.008621434 2.1 381 22 4 9 50 48 29 N N N N N N EXOSC7 high in P 2.0 0.008627606 2.1 382 31 36 34 66 56 77 N N N N N N C6orf211 high in P 3.1 0.008633777 2.1 383 27 23 15 142 50 59 N N N N N N THBD high in P 3.3 0.008639948 2.1 384 14 24 25 88 42 41 N P N N N N KIAA2026 high in P 2.0 0.008665318 2.1 385 42 52 35 78 82 86 N N N N N N BMF high in P 7.0 0.008709202 2.1 386 9 51 20 256 145 58 N N N N N N PAPPA high in P 6.6 0.008715373 2.1 387 27 57 42 232 154 63 P N N N N N G9orf80 high in P 2.4 0.008766799 2.1 388 97 72 112 255 202 190 N N N N N N SLC25A43 high in P 2.3 0.008803826 2.1 389 93 132 110 194 282 197 N N N N N N PRPS1 high in P 4.3 0.008825082 2.1 390 28 65 37 81 134 186 N N N N N N BNIP2 high in P 4.0 0.008880623 2.1 391 124 55 58 257 210 198 N N N N N N GMFG high in P 6.8 0.008901879 2.1 392 2 3 11 86 42 18 N N N N N N SFXN1 high in P 2.7 0.008916964 2.0 393 30 53 54 138 92 102 N N N N N N BAZ1B high in P 3.0 0.008950562 2.0 394 93 184 251 417 518 434 N N N N N N RRN3P3 high in P 2.6 0.008975933 2.0 395 987 1008 979 2961 2394 1615 NA NA N N N N EGR2 high in P 3.9 0.009030787 2.0 396 18 30 21 47 68 158 P P N N N N SFRS2IP high in P 2.4 0.009036958 2.0 397 71 75 99 186 179 140 N N N N N N SLC30A4 high in P 2.4 0.009047929 2.0 398 12 22 15 38 25 39 N N N N N N CST7 high in P 10.2 0.0090541 2.0 399 4 8 31 79 73 69 N N N N N N CROCCL1 high in P 4.1 0.009085642 2.0 400 82 174 58 288 235 389 NA NA N N N N PITPNB high in P 2.9 0.009091813 2.0 401 205 195 341 554 539 829 N N N N N N LRRC1 high in P 3.0 0.009097984 2.0 402 31 62 80 222 143 150 N N N N N N FGL2 high in P 2.7 0.009150096 2.0 403 33 21 27 58 55 52 N N N N N N HEATR1 high in P 2.8 0.009171352 2.0 404 58 129 71 163 247 180 N N P N N N DOCK9 high in P 5.0 0.009177523 2.0 405 26 54 79 310 133 126 N N N N N N RAB3A high in P 6.6 0.009183694 2.0 406 47 7 14 90 119 82 N N N N N N EPB41L3 high in P 3.7 0.009198779 2.0 407 11 19 13 33 38 24 P P N N N N BCS1L high in P 2.3 0.009204951 2.0 408 6 8 7 25 16 15 N N N N N N SESN1 high in P 3.6 0.009234435 2.0 409 150 93 66 251 256 372 N N N N N N IGFL1 high in P 18.6 0.009240606 2.0 410 3 65 41 825 514 100 N N N N N N POMGNT1 high in P 2.4 0.009252948 2.0 411 211 306 340 653 607 521 N N N N N N C4orf14 high in P 4.9 0.009270776 2.0 412 352 162 150 617 620 603 N N N N N N HCCS high in P 2.3 0.009287918 2.0 413 257 160 234 492 509 488 P P N N N N LRCH1 high in P 2.9 0.009294089 2.0 414 368 364 661 1024 1038 1461 N N N N N N MGAT4A high in P 2.2 0.009331116 2.0 415 33 47 33 82 61 71 N N N N N N SLC28A3 high in P 2.4 0.009521736 2.0 416 23 18 18 55 54 37 N N N N N N C17orf67 high in P 13.3 0.009545735 2.0 417 10 6 54 169 120 85 N N N N N N MAPRE2 high in P 2.3 0.009564248 2.0 418 16 20 26 46 41 50 N N N N N N SENP1 high in P 2.8 0.009581391 2.0 419 33 70 40 121 106 85 N N N N N N INPP5A high in P 2.6 0.009605389 2.0 420 38 99 63 179 139 150 N N N N N N SULT1A4 high in P 3.7 0.009617732 2.0 421 135 234 344 526 702 937 N N N N N N ATP10D high in P 3.8 0.009664358 2.0 422 13 24 15 49 27 60 N N N N N N PDE1B high in P 5.9 0.009670529 2.0 423 8 8 10 79 31 16 P P N N N N ZBTB7C high in P 2.6 0.009690414 2.0 424 31 67 42 100 88 84 N N N N N N PPM1H high in P 3.6 0.009713727 2.0 425 16 45 19 138 61 56 N N N N N N PQLC1 high in P 2.8 0.009725384 2.0 426 409 646 1017 1705 1635 1908 N N N N N N FLVCR1 high in P 2.2 0.009731555 2.0 427 33 32 36 60 71 52 N N N N N N METTL5 high in P 3.2 0.009741155 2.0 428 51 38 21 100 108 68 N N N N N N PATH high in P 3.2 0.009754183 2.0 429 450 408 362 1196 671 1399 N N N N N N FAM43A high in P 3.2 0.00977681 2.0 430 184 90 164 564 395 354 N N N N N P GSTCD high in P 2.5 0.009798752 2.0 431 24 23 18 41 41 44 N N N N N N DYNLL1 high in P 2.7 0.009808352 2.0 432 2113 1381 2830 6119 4751 7380 N N N N N N ZNF121 high in P 3.6 0.009824122 2.0 433 7 8 14 28 27 23 N P N N N N SLC25A22 high in P 2.4 0.009830293 2.0 434 34 26 27 84 88 51 N N N N P N GPR56 high in P 2.6 0.009877606 2.0 435 16 20 24 31 42 37 N N N N N N SLC25A3 high in P 2.8 0.009889948 2.0 436 167 155 138 407 433 240 N N N N N N ZEB1 high in P 3.0 0.009918061 2.0 437 14 25 15 53 33 36 N P N N N N CARD10 high in P 2.3 0.009946174 2.0 438 163 185 240 348 403 480 N N N N N P ZNF18 high in P 4.0 0.009970858 2.0 439 14 25 19 89 58 36 N N N N N N SDK1 high in P 4.1 0.010009942 2.0 440 24 25 26 62 48 32 N N N N N N ZNF836 high in P 4.1 0.010016114 2.0 441 7 7 18 35 47 31 N N N N N N TTL high in P 2.3 0.010137479 2.0 442 98 164 137 311 241 217 N N N N N N MRPS6 high in P 3.5 0.010143651 2.0 443 22 28 42 115 86 65 N N N N N N ENC1 high in P 4.5 0.010155307 2.0 444 62 39 30 113 115 97 N N N N N N TNFRSF4 high in P 13.6 0.010167649 2.0 445 7 2 35 270 155 39 N N N N N N CSNK2A1P high in P 4.4 0.010186849 2.0 446 289 223 669 1654 1169 1028 N N N N N N VHL high in P 3.6 0.010199191 2.0 447 247 607 356 1232 1163 807 N N N N N N LOC493754 high in P 3.7 0.010205362 2.0 448 783 221 513 1565 1805 2135 N N N N N N UGP2 high in P 3.0 0.01021839 2.0 449 62 77 40 109 134 179 N N N N N N SLC23A2 high in P 2.0 0.010238275 2.0 450 62 76 76 118 162 113 N N N N N N FUT6 high in P 2.8 0.010244446 2.0 451 3 4 4 22 11 9 N N N N N N RIPK1 high in P 4.1 0.010273245 2.0 452 32 87 81 317 251 129 N N N N N N TNFRSF6B high in P 4.9 0.010279416 2.0 453 55 205 96 679 584 223 N N N N N N NHLRC1 high in P 2.4 0.010285587 2.0 454 11 16 16 30 48 29 N N N N N N CCDC117 high in P 3.9 0.0103185 2.0 455 32 54 72 241 129 115 N N N N N N ZNF691 high in P 4.1 0.010333585 2.0 456 4 5 4 8 11 15 N N N N N N CRISPLD2 high in P 4.1 0.010384325 2.0 457 87 131 238 803 460 306 P N N N N N MTHFD2L high in P 3.9 0.010422724 2.0 458 19 37 47 61 111 152 NA NA N N N N MRVI1 high in P 3.7 0.010428895 2.0 459 17 17 17 25 29 21 N N N N N N GPATCH8 high in P 2.3 0.010465236 2.0 460 22 41 53 70 70 78 N N N N N N PLOD3 high in P 4.7 0.010526262 2.0 461 138 215 452 788 764 694 N N N N N N FABP3 high in P 7.0 0.010553689 2.0 462 4 4 14 22 31 82 N N N N N N TPD52L2 high in P 2.0 0.010597573 2.0 463 787 1340 1298 2467 2286 2474 N N N N N P FBXL14 high in P 3.5 0.010603744 2.0 464 6 14 8 24 20 22 N N N N N N DAGLA high in P 2.3 0.010618829 2.0 465 34 49 29 64 59 69 N N N N N N BTRC high in P 3.1 0.010707968 2.0 466 17 46 52 79 112 127 N N N N P N ATP5E high in P 2.4 0.010717567 2.0 467 2 2 2 6 5 10 N N N N N N C2orf68 high in P 3.8 0.01074088 2.0 468 30 156 184 614 489 342 N N N N N N DCLRE1C high in P 3.5 0.010747052 2.0 469 49 43 92 240 224 108 N N N N N N SPR high in P 2.7 0.015295872 1.8 602 23 40 31 95 89 46 N N N N N N PRO0628 high in P 6.2 0.015422038 1.8 603 37 5 10 105 74 38 N N N N N N VWF high in P 4.7 0.015431637 1.8 604 43 43 73 236 105 91 P N N N N N CASP8 high in P 2.5 0.015450837 1.8 605 93 253 233 450 540 432 N N N N N N DGKZ high in P 2.0 0.015479635 1.8 606 195 190 204 296 419 356 N N N N N N CHRDL2 high in P 4.9 0.015549575 1.8 607 3 14 3 16 21 38 P P N N N N HMGB1L1 high in P 5.3 0.015555746 1.8 608 NA NA NA NA NA NA NA NA N N N N CXCL12 high in P 1.9 0.015642142 1.8 609 22 31 25 38 37 36 P N N N N N CACNB1 high in P 5.4 0.01572031 1.8 610 59 94 219 264 335 478 N N N N N N LRRC37A3 high in P 7.4 0.015731281 1.8 611 7 12 54 86 103 90 N N N N N N SNAI2 high in P 5.1 0.01575528 1.8 612 17 14 13 37 19 73 N P N N N N SNX5 high in P 2.7 0.015764879 1.8 613 538 267 400 975 1074 780 N N N N N N RNF26 high in P 3.7 0.015801906 1.8 614 115 208 321 695 613 394 N N N N N N APOLD1 high in P 4.8 0.015821791 1.8 615 27 95 60 351 123 146 N N N N N N GGNBP2 high in P 2.3 0.015827962 1.8 616 566 406 346 835 843 1031 N N N N N N ZC3H7B high in P 3.3 0.015851961 1.8 617 85 105 218 314 309 275 N N N N N N AASDHPPT high in P 2.5 0.01588556 1.8 618 49 65 31 87 126 106 N N N N N N POLH high in P 2.2 0.015932186 1.8 619 120 131 195 345 304 242 N N N N N N ZNF516 high in P 2.7 0.015953442 1.8 620 50 41 30 84 86 83 N N N N N N C11or75 high in P 2.3 0.015984984 1.8 621 16 16 20 32 36 53 N N N N N N GPIHBP1 high in P 7.0 0.016239372 1.8 622 8 16 41 145 79 55 P N N N N N KCTD12 high in P 2.3 0.016245543 1.8 623 52 55 34 92 84 110 N N N N N N FRG1 high in P 2.7 0.016283256 1.8 624 46 68 60 171 149 87 N N N N N N COL6A2 high in P 3.1 0.016314111 1.8 625 830 3095 2054 4077 5768 8389 P N N N N N N4BP1 high in P 1.7 0.016358681 1.8 626 189 266 226 375 351 325 N N N N N N MY019 high in P 1.9 0.016395022 1.8 627 146 141 120 207 236 262 N N N N N N MST1R high in P 2.4 0.016448505 1.8 628 48 53 33 76 99 97 N N N N N N SLC37A1 high in P 2.5 0.016459476 1.8 629 230 499 450 1089 902 666 N N N N N N KIAA0196 high in P 2.8 0.016482104 1.8 630 8 10 12 28 15 22 N N N N N N POLR3E high in P 5.5 0.016521188 1.8 631 73 84 263 363 391 393 N N N N N N RAB2B high in P 2.4 0.016553415 1.8 632 47 29 60 134 97 98 N N N N N N WNK1 high in P 2.0 0.016559586 1.8 633 242 302 279 486 412 557 N N N N N N EFNB3 high in P 2.7 0.016586327 1.8 634 88 76 135 222 178 218 N N N N N N NAA15 high in P 2.7 0.016645982 1.8 635 50 71 75 92 168 163 NA NA N N N N LRG1 high in P 5.1 0.016666552 1.8 636 51 198 404 775 800 665 N N N N N N FHL1 high in P 2.5 0.016686437 1.8 637 11 11 11 21 14 14 P P N N N N CHST6 high in P 2.2 0.016702208 1.8 638 135 94 149 276 291 215 N N N N N N YY1AP1 high in P 2.4 0.016730321 1.8 639 241 245 177 391 408 743 N N N N N N TCEB3 high in P 2.0 0.01673992 1.8 640 179 352 339 624 540 567 N N N N N N IMPA2 high in P 3.1 0.016759805 1.8 641 106 180 144 807 400 219 N N N N N N MMAA high in P 2.8 0.016781061 1.8 642 16 31 15 46 34 77 N N N N N N ZBTB5 high in P 2.5 0.016787233 1.8 643 216 102 168 352 367 397 N N N N N N PPP3CC high in P 2.2 0.016811231 1.8 644 86 140 141 195 230 273 N N N N N N RAD 18 high in P 2.0 0.016872943 1.8 645 46 74 79 109 136 105 N N N N N N PRSS36 high in P 3.3 0.010816306 2.0 470 31 16 15 85 54 39 N N N N N N C4orf32 high in P 2.4 0.010830019 2.0 471 23 29 18 49 36 65 N N N N N N RASD2 high in P 2.9 0.010845104 2.0 472 20 12 13 45 28 32 N N N N N N TRIM16 high in P 4.5 0.010851275 2.0 473 844 909 2910 7373 6954 3662 N N N N N N GDAP1 high in P 2.7 0.010878703 2.0 474 21 23 17 57 57 32 N N N N N N PPM1D high in P 5.2 0.010884874 2.0 475 92 43 22 184 133 163 N N N N N N DLL4 high in P 2.6 0.010929443 2.0 476 7 8 7 11 12 18 P P N N N N UBA5 high in P 3.1 0.010959613 2.0 477 162 159 135 405 540 238 N N N N N N ASCC1 high in P 2.5 0.010970584 2.0 478 110 127 108 424 257 190 N N N N N N TWIST1 high in P 6.2 0.011065894 2.0 479 7 7 7 36 21 10 P P N N N N SLC44A1 high in P 2.9 0.01108715 2.0 480 223 426 278 1068 643 590 N N N N N N JAM2 high in P 2.6 0.011093321 2.0 481 2 4 2 10 8 11 N N N N N N PODXL high in P 4.6 0.011123491 2.0 482 542 191 277 1520 809 1005 N N N N N N TOPORS high in P 2.7 0.011179032 2.0 483 45 69 28 105 90 123 N N N N N N SPRY2 high in P 4.7 0.011244172 1.9 484 92 45 31 191 126 210 N N N N N N RAB4B high in P 2.8 0.011261999 1.9 485 16 24 13 55 46 29 N N N N N N CP high in P 5.3 0.011289427 1.9 486 21 26 11 101 62 38 N N N N N N NXF1 high in P 2.2 0.011299026 1.9 487 1433 2024 2428 4578 3821 4692 N N N N N N DPY30 high in P 2.6 0.011404622 1.9 488 47 88 48 126 121 113 N N N N N N FAM50B high in P 5.6 0.011432735 1.9 489 14 37 53 167 158 72 N N N N N N ACOX3 high in P 3.3 0.011491018 1.9 490 153 125 252 612 513 313 N N N N N N EFNB1 high in P 4.1 0.011497189 1.9 491 42 103 99 671 313 154 P P N N N N ABCB4 high in P 4.0 0.01150336 1.9 492 2 4 3 14 8 18 P P N N N N C15orf17 high in P 2.5 0.011578785 1.9 493 155 179 220 295 409 472 N N N N N N ASXL1 high in P 2.6 0.01162884 1.9 494 87 70 88 155 171 208 N N N N N N MMP2 high in P 5.4 0.011635011 1.9 495 20 20 29 131 45 46 P N N N N N C13orf27 high in P 3.3 0.011715922 1.9 496 3 29 17 64 54 72 N N N N N N ZNF93 high in P 3.6 0.011752948 1.9 497 81 65 37 322 126 143 N N N N N N AARSD1 high in P 3.1 0.01175912 1.9 498 62 36 37 120 111 85 N N N N N N VWDE high in P 3.5 0.011808489 1.9 499 6 6 6 29 19 11 N N N N N N RBM23 high in P 2.0 0.01181466 1.9 500 289 342 408 660 708 560 N N N N N N HSPG2 high in P 2.7 0.011820831 1.9 501 232 275 374 508 594 852 N N N N N N ZNF692 high in P 2.7 0.011864029 1.9 502 373 155 395 893 815 1012 N N N N N N XPO1 high in P 3.1 0.0118702 1.9 503 496 489 255 909 952 1518 N N N N N N MUC16 high in P 3.4 0.011913398 1.9 504 72 319 500 853 786 978 P N N N N N VPS25 high in P 2.9 0.011938083 1.9 505 370 532 483 2213 1294 761 N N N N N N SORBS2 high in P 4.2 0.011963453 1.9 506 43 93 30 307 196 99 N N N N N N PCDHB15 high in P 2.5 0.011969624 1.9 507 1 1 1 8 4 4 N N N N N N FGFRL1 high in P 3.2 0.011975795 1.9 508 156 179 282 376 797 590 N N N N N N COL2A1 high in P 2.6 0.012032707 1.9 509 7 7 9 15 12 13 P N N N N N ABI2 high in P 2.3 0.012048478 1.9 510 33 36 41 98 64 59 N N N N N N C14orf19 high in P 1.9 0.012087562 1.9 511 8 20 19 29 33 30 N N N N N N GLIPR1L2 high in P 2.3 0.012102647 1.9 512 16 14 17 38 25 39 N N N N N N C10or54 high in P 3.2 0.012217841 1.9 513 29 33 46 91 63 59 N N N N N N NPTX2 high in P 4.4 0.012230184 1.9 514 6 15 7 28 22 23 P P N N N N CXCR7 high in P 12.3 0.012236355 1.9 515 9 38 44 407 208 78 P N N N N N SERPINB6 high in P 3.1 0.012305609 1.9 516 411 565 952 2632 1810 1215 N N N N N N PPID high in P 2.8 0.012330293 1.9 517 14 12 19 34 30 58 N N N N N N BST2 high in P 2.0 0.012350864 1.9 518 251 188 278 476 486 487 N N N N N N ARF1 high in P 2.2 0.012357035 1.9 519 7837 11722 11046 23407 21071 16056 N N N N N N PLD6 high in P 3.8 0.012421489 1.9 520 14 25 40 111 61 75 N N N N N N TECR high in P 2.4 0.01242766 1.9 521 949 793 1241 2926 2464 1664 NA NA N N N N TIPIN high in P 2.3 0.01246263 1.9 522 11 12 9 28 29 18 N N N N N N SMARCA4 high in P 4.5 0.012536684 1.9 523 899 778 2839 5587 6092 3534 N N N N N N HEXA high in P 4.2 0.012577139 1.9 524 102 38 46 173 165 164 N N N N N N EGFL7 high in P 7.5 0.012594281 1.9 525 9 25 62 265 124 116 P P N N N N SLC45A4 high in P 4.5 0.012610052 1.9 526 24 37 72 165 146 92 N N N N N N CAPZB high in P 2.6 0.012699191 1.9 527 2967 2802 3278 9702 8022 5373 N N N N P N SENP7 high in P 2.7 0.012744446 1.9 528 11 13 13 25 21 29 N P N N N N FTSJ3 high in P 3.9 0.01278833 1.9 529 13 77 41 158 100 141 N N N N N N SART1 high in P 2.5 0.012803415 1.9 530 404 253 542 943 1093 867 N N N N N N AATF high in P 2.4 0.012956322 1.9 531 46 104 67 151 152 159 P P N N P N LOC150381 high in P 3.0 0.012968664 1.9 532 117 96 177 364 334 233 NA NA N N N N ZXDC high in P 1.9 0.012981007 1.9 533 250 281 348 591 490 475 N N N N N N CRTC2 high in P 4.2 0.013017348 1.9 534 95 86 229 388 413 274 N N N N N N SDF4 high in P 2.9 0.013057117 1.9 535 524 1003 741 2677 1987 1270 N N N N N N ATR high in P 2.4 0.013096887 1.9 536 40 54 68 140 100 86 N N N N N N LALBA high in P 10.1 0.013110601 1.9 537 2 2 3 6 16 140 N N N N N N REC8 high in P 2.2 0.013116772 1.9 538 44 58 57 90 93 118 N N N N N P TNFRSF1B high in P 8.6 0.013148313 1.9 539 220 590 1581 5134 4626 1846 N N N N N N TIMM17B high in P 3.0 0.013161341 1.9 540 338 161 247 703 668 508 N N N N N N MRPL34 high in P 5.8 0.013248423 1.9 541 286 184 759 2776 2178 807 N N N N N N ACTR5 high in P 3.8 0.013254594 1.9 542 59 107 193 324 327 287 N N N N N N ARHGAP23 high in P 2.3 0.013282707 1.9 543 111 197 161 337 241 306 NA NA N N N N RINT1 high in P 2.9 0.013288878 1.9 544 71 93 42 185 181 112 N N N N N N POLR2A high in P 2.4 0.013325219 1.9 545 582 810 445 1778 1203 1186 N N N N N N FAM114A1 high in P 2.4 0.013349218 1.9 546 19 28 16 63 37 40 N N N N N N ZNF521 high in P 3.3 0.013386931 1.9 547 16 20 16 42 26 30 N N N N N N KDM5C high in P 3.9 0.013393102 1.9 548 357 169 186 674 603 516 NA NA N N N N KCNH3 high in P 2.9 0.0134315 1.9 549 10 14 15 28 24 28 P P N N N N CNBP high in P 4.0 0.01350144 1.9 550 334 214 150 679 503 667 N N N N N N LOC100133957 high in P 2.2 0.013512411 1.9 551 49 38 27 70 67 83 NA NA N N N N ACTL6A high in P 4.9 0.013564523 1.9 552 5 29 7 53 29 54 N N N N N N DCTN2 high in P 3.8 0.013593321 1.9 553 2191 1284 670 6078 4682 3236 P P N N N N IFITM1 high in P 4.0 0.013606349 1.9 554 79 195 65 564 277 220 N N N N N N EFNA1 high in P 3.2 0.013666004 1.9 555 1363 784 645 2067 2338 2282 N N N N N N KANK2 high in P 2.6 0.013685889 1.9 556 16 19 16 29 29 24 N N N N N N LPCAT1 high in P 3.3 0.01369206 1.9 557 69 123 203 370 259 336 N N N N N N CALU high in P 2.4 0.01372223 1.9 558 492 382 370 1165 967 650 N N N N N N HTATSF1 high in P 2.5 0.013750343 1.9 559 13 11 16 37 28 26 P N N N N N SHROOM3 high in P 4.7 0.013759942 1.9 560 1510 657 500 3867 2748 1952 N N N N N N CLCN5 high in P 2.3 0.013776399 1.9 561 19 23 20 31 31 34 N N N N N N HLA-DOB high in P 3.7 0.01378257 1.9 562 15 6 6 39 24 16 N N N N N N CRABP2 high in P 2.0 0.013838796 1.9 563 5826 3425 6730 10149 11163 10924 N N N N N N IDE high in P 2.8 0.013844967 1.9 564 79 149 111 286 346 171 N N N N N N MCOLN2 high in P 2.6 0.013902564 1.9 565 45 56 89 139 113 144 N P N N N N ABLIM2 high in P 3.2 0.013981418 1.9 566 8 13 14 73 33 21 N N N N N N NT5DC3 high in P 3.3 0.013987589 1.9 567 187 176 143 325 370 1043 N N N N N N C15orf24 high in P 2.7 0.014010217 1.9 568 91 121 53 230 227 147 N N N N N N TMEM213 high in P 2.9 0.014075357 1.9 569 133 76 76 269 184 193 N N N N N N ISOC2 high in P 2.6 0.014095241 1.9 570 90 170 182 364 379 248 N N N N N N SLC10A7 high in P 3.0 0.014141182 1.8 571 26 12 19 56 41 48 N N N N N N HSPE1 high in P 7.5 0.014272148 1.8 572 11 11 44 55 175 69 N N N N N N HADHA high in P 1.9 0.014278319 1.8 573 934 1112 1329 2174 1866 2063 N N N N N N SMCR8 high in P 2.9 0.014387342 1.8 574 101 243 252 634 422 434 N N N N N N KLF11 high in P 4.4 0.014416827 1.8 575 192 52 202 757 388 550 N N N N N N SLC25A25 high in P 6.4 0.014432597 1.8 576 761 250 193 1319 951 1743 N N N N N N ZBTB39 high in P 2.6 0.014477852 1.8 577 14 25 27 58 32 51 N N N N N N CHMP4C high in P 2.2 0.014492937 1.8 578 117 94 94 321 196 166 N N N N N N SEC22B high in P 2.3 0.014505965 1.8 579 136 171 134 402 304 219 P N N N N N EVPL high in P 4.3 0.014551906 1.8 580 200 138 491 727 874 779 N N N N N N MAP1A high in P 2.8 0.014580019 1.8 581 20 22 22 30 26 39 P P N N N N GEN1 high in P 2.6 0.014618417 1.8 582 20 24 26 54 37 35 N N N N N N C13orf high in P 2.0 0.014650645 1.8 583 55 55 41 118 73 86 N N N N N N PMS2 high in P 3.1 0.014680129 1.8 584 50 43 79 129 138 109 N N N N N N PTAR1 high in P 2.3 0.014715784 1.8 585 126 116 76 207 259 202 N N N N N N PLLP high in P 2.8 0.014752811 1.8 586 80 60 35 146 136 98 N N N N N N C11orf54 high in P 2.3 0.014777496 1.8 587 63 108 94 258 144 166 N N N N N N TNFSF10 high in P 2.3 0.014804238 1.8 588 554 443 607 1459 1035 887 N N N N N N C6orf15 high in P 5.3 0.014829608 1.8 589 10 15 38 108 189 41 N N N N N N TMTC1 high in P 2.2 0.014849493 1.8 590 73 53 56 89 95 119 P P N N N N GATS high in P 2.6 0.014898176 1.8 591 26 69 56 144 120 94 N N N N N N PPP2R5B high in P 2.7 0.01497223 1.8 592 819 451 523 1159 1325 1559 N N N N P N SHKBP1 high in P 4.7 0.014978401 1.8 593 99 210 374 1629 1025 410 N N N N N N NDUFS2 high in P 2.1 0.015040112 1.8 594 14 15 19 32 31 26 N N N N N N FZD5 high in P 6.2 0.015090167 1.8 595 38 87 228 407 365 295 N N N N N N ELN high in P 3.5 0.015211533 1.8 596 12 12 14 18 25 48 P P N N N N PCBD2 high in P 2.1 0.015236218 1.8 597 71 61 64 139 140 101 N N N N N P LCORL high in P 2.0 0.015242389 1.8 598 13 24 17 30 31 24 N N N N N P SYT12 high in P 2.3 0.015257474 1.8 599 20 50 37 76 56 86 N N N N N N SLC22A9 high in P 2.6 0.015263645 1.8 600 3 4 3 9 8 6 N P N N N N MEIS3P1 high in P 2.1 0.015289701 1.8 601 22 37 25 50 45 59 N N N N N N GMPS high in P 2.9 0.016879114 1.8 646 177 110 80 258 299 234 N N N N N N BID high in P 2.3 0.01701008 1.8 647 311 215 249 435 532 581 N N N N N N POLG high in P 2.3 0.017123903 1.8 648 820 723 1286 1830 2241 1900 N N N N N N SORBS1 high in P 2.0 0.017180129 1.8 649 86 191 193 315 299 345 N N N N N N PGBD2 high in P 2.0 0.0171863 1.8 650 9 9 9 13 12 12 N N N N N N CLECAE high in P 2.5 0.01730218 1.8 651 4 5 5 39 11 12 N N N N N N RANBP9 high in P 2.7 0.017317265 1.8 652 375 262 205 776 493 590 N N N N N N HTRA4 high in P 2.3 0.017338522 1.8 653 79 60 43 122 111 99 N N N N N N GPX3 high in P 3.4 0.017450288 1.8 654 17 58 67 168 136 74 N N N N N N ADAMTS9 high in P 2.5 0.017463316 1.8 655 146 175 103 297 250 355 N N N N N N RAD52 high in P 3.2 0.017538055 1.8 656 6 15 9 18 24 37 N N N N N N CBARA1 high in P 2.1 0.017544227 1.8 657 136 102 116 238 232 181 N N N N N N PPAPDC2 high in P 2.7 0.017559997 1.8 658 20 62 39 136 101 69 N N N N N N SLC2A3 high in P 5.4 0.017588796 1.8 659 17 22 33 97 33 131 N N N N N N CETN2 high in P 2.8 0.017604567 1.8 660 362 298 170 688 685 508 P N N N N N RRAGA high in P 2.2 0.017664907 1.8 661 430 691 638 1508 1197 922 N N N N N N CUL2 high in P 2.7 0.017705362 1.8 662 185 123 106 266 336 240 N N N N N N TMEM212 high in P 3.9 0.017724561 1.8 663 353 105 197 648 666 515 NA NA N N N N FCHO2 high in P 3.0 0.017730732 1.8 664 15 19 24 53 30 82 N N N N N N CSGALNACT1 high in P 4.5 0.017762274 1.8 665 28 48 27 225 123 47 N N N N N N C12orf5 high in P 1.8 0.017817814 1.7 666 55 55 68 104 100 96 N N N N N N S100A7 high in P 49.4 0.017834956 1.7 667 1 63 398 3939 2152 417 P N N N N N PSMA7 high in P 2.0 0.017847298 1.7 668 2189 2813 1923 4958 5050 3959 N N N N N N DRG1 high in P 7.3 0.017909696 1.7 669 26 48 139 274 281 148 N N N N N N TCFL5 high in P 2.0 0.017922038 1.7 670 17 22 21 29 44 33 N N N N N N TIMP4 high in P 3.5 0.017970721 1.7 671 6 6 6 26 11 11 N N N N N N DLAT high in P 3.4 0.017980321 1.7 672 35 129 79 289 257 138 N N N N N N OLFM2 high in P 4.4 0.01800912 1.7 673 36 42 112 148 154 138 N N N N N N TM2D2 high in P 3.6 0.018072202 1.7 674 45 104 206 365 282 279 N N N N N N NT5C2 high in P 2.3 0.018125 1.7 675 221 188 119 360 334 396 N N N N N N RTN4RL2 high in P 5.1 0.01815037 1.7 676 14 61 128 236 242 254 N N N N N N NOL6 high in P 12.1 0.018156541 1.7 677 17 52 249 213 498 498 N N N N N N TSR1 high in P 2.4 0.01824088 1.7 678 43 41 34 95 82 54 N N N N N N CCDC55 high in P 2.6 0.018247052 1.7 679 257 170 299 684 550 421 N N N N N N ADO high in P 2.6 0.018270365 1.7 680 39 106 116 189 220 214 P N N N N N VCAN high in P 2.9 0.018359504 1.7 681 28 29 28 58 33 36 P N N N N N ANAPC1 high in P 6.1 0.018384874 1.7 682 97 157 452 562 691 727 N N N N N N GSN high in P 1.9 0.018415044 1.7 683 871 1456 1695 3492 2692 2550 N N N N N N RDH16 high in P 4.1 0.018519268 1.7 684 1 4 2 25 14 9 N N N N N N REV1 high in P 2.7 0.018578922 1.7 685 77 88 142 203 215 168 N N N N N N GNG4 high in P 3.3 0.018606349 1.7 686 13 28 33 64 63 42 N P N N N N MLH1 high in P 2.2 0.018640634 1.7 687 21 47 29 68 57 77 N N N N N N CTCF high in P 2.5 0.018655719 1.7 688 38 93 47 189 114 95 N N N N N N STARD3NL high in P 2.0 0.018862109 1.7 689 150 179 135 295 368 219 N N N N N N ZDHHC2 high in P 2.0 0.018896393 1.7 690 15 18 12 26 32 23 N N N N N N COX 11 high in P 1.8 0.018912164 1.7 691 15 23 18 28 38 28 N N N N N N NCRNA00201 high in P 2.1 0.018925192 1.7 692 25 30 22 39 47 46 NA NA N N N N AP4S1 high in P 5.0 0.018945077 1.7 693 435 131 141 591 529 863 N N N N N N CSor78 high in P 2.6 0.018962905 1.7 694 111 311 193 567 408 442 N N N N N N ZFP41 high in P 2.9 0.01897799 1.7 695 25 24 48 102 70 63 N N N N N N FAM70B high in P 5.4 0.019052729 1.7 696 1 2 3 34 8 12 P P N N N N CLEC17A high in P 3.5 0.01909867 1.7 697 4 4 6 8 16 34 N N N N N N SNHG10 high in P 2.9 0.019113755 1.7 698 18 11 11 32 25 60 N N N N N N KTELC1 high in P 3.0 0.019119926 1.7 699 32 55 69 188 160 75 N N N N N N ABL1 high in P 2.2 0.019157639 1.7 700 280 585 402 813 834 714 N N N N N N PIGS high in P 2.4 0.01916381 1.7 701 156 195 107 461 370 225 N N N N N N GGA2 high in P 2.5 0.019258434 1.7 702 98 73 88 213 151 176 N N N N N N ADORA2A high in P 3.3 0.019264605 1.7 703 29 99 61 160 114 261 N N N N N N PODN high in P 5.1 0.019330431 1.7 704 12 12 13 27 15 35 N P N N N P PSMC6 high in P 1.8 0.019376371 1.7 705 523 536 320 813 878 800 N N N N N N DDTL high in P 4.5 0.019415455 1.7 706 45 18 42 77 168 74 N N N N N P MLXIPL high in P 2.7 0.019470996 1.7 707 16 37 51 127 71 69 N N N N N N ZNF570 high in P 4.4 0.019477167 1.7 708 2 8 11 36 35 20 N N N N N N SECISBP2 high in P 4.5 0.019548478 1.7 709 213 486 986 2100 1904 1135 N N N N N N SERPINH1 high in P 2.8 0.019582762 1.7 710 126 252 205 330 370 596 N N N N N N GPR115 high in P 2.8 0.019588933 1.7 711 4 4 4 12 11 7 N N N N N N RNMTL1 high in P 2.0 0.019632131 1.7 712 65 124 116 209 167 203 N N N N N N KCNQ5 high in P 2.1 0.019684243 1.7 713 5 5 5 7 10 8 N N N N N N LOC642587 high in P 4.1 0.019690414 1.7 714 399 937 2184 3499 3776 3439 N N N N N N GCDH high in P 2.4 0.019696585 1.7 715 52 79 109 200 164 134 N N N N N N C6orf120 high in P 3.4 0.019779553 1.7 716 180 111 241 356 674 355 N N N N P N SMURF1 high in P 5.2 0.019826179 1.7 717 1096 917 4042 6959 6504 4522 N N N N N N AVPH high in P 2.2 0.019835779 1.7 718 99 72 77 215 161 120 N N N N N N KRT14 high in P 4.3 0.019918061 1.7 719 397 1245 777 1621 2899 14028 N N N N N N CBLL1 high in P 2.1 0.019933146 1.7 720 124 126 181 296 241 215 N N N N N N AFTPH high in P 2.5 0.019948917 1.7 721 513 356 267 668 744 1118 N N N N N N KIAA1919 high in P 2.5 0.01996743 1.7 722 19 45 28 75 71 47 N N N N N N C1orf27 high in P 1.8 0.019973601 1.7 723 121 142 117 199 268 184 N N N N N N PREPL high in P 1.8 0.019998971 1.7 724 28 35 36 47 59 69 N N N N N N ROBO4 high in P 3.0 0.020008571 1.7 725 14 13 9 62 22 20 P N N N N N C6orf64 high in P 2.0 0.020091539 1.7 726 60 118 98 191 178 145 N N N N N N TNRC6B high in P 2.1 0.02009771 1.7 727 103 126 105 280 217 156 N N P N N N RAP1GDS1 high in P 3.1 0.020195077 1.7 728 12 37 33 64 83 46 N N N N N N PDZRN3 high in P 2.2 0.020236903 1.7 729 19 17 16 22 24 30 N N N N N N BTBD10 high in P 2.0 0.020282844 1.7 730 78 138 149 205 278 229 N N N N N N TCF4 high in P 3.3 0.020478264 1.7 731 28 51 34 287 100 49 P P N N P N ITGAL high in P 3.1 0.020498834 1.7 732 6 7 13 27 27 15 N N N N N N PLB1 high in P 2.8 0.020528319 1.7 733 7 15 16 43 42 20 N N N N N N IFI16 high in P 3.4 0.020575631 1.7 734 66 203 168 320 277 527 N N N N N N CKB high in P 2.1 0.020600315 1.7 735 1444 758 1606 2764 2914 3474 N N N N N N TMEM169 high in P 2.2 0.020640771 1.7 736 21 20 15 46 33 28 N N N N N N LOC554202 high in P 3.9 0.02065997 1.7 737 11 11 12 15 16 39 NA NA N N N N CHIC1 high in P 3.5 0.020676426 1.7 738 13 35 18 46 35 45 N N N N N N ALOX12P2 high in P 2.3 0.020682597 1.7 739 7 16 13 49 23 20 N N N N N N REEP4 high in P 2.6 0.020697682 1.7 740 104 124 209 289 392 243 N N N N N N TMEM81 high in P 4.6 0.020710025 1.7 741 2 7 4 14 12 33 N N N N N N LOC642313 high in P 5.6 0.020722367 1.7 742 3 6 15 32 24 34 NA NA N N N N HIVEP3 high in P 2.9 0.020758708 1.7 743 139 283 369 414 653 890 N N N N N N MAF high in P 2.4 0.020764879 1.7 744 34 34 36 62 44 55 N N N N N N GOS2 high in P 5.6 0.020779964 1.7 745 102 75 35 105 324 687 P N N N N N MRPL14 high in P 2.1 0.020800535 1.7 746 1495 1085 1115 2389 2675 1945 N N N N N N PKP4 high in P 3.3 0.020819048 1.7 747 984 484 1447 3887 3319 1735 N N N N N N CLDN10 high in P 2.7 0.020899273 1.7 748 5 8 5 42 16 11 N N N N N N RASSF4 high in P 7.1 0.02091093 1.7 749 96 58 332 1103 595 300 N N N N N N MRPL33 high in P 2.1 0.020917101 1.7 750 1023 792 823 2476 1701 1340 N N N N N N SFRS13A high in P 2.2 0.02104121 1.7 751 184 107 164 275 321 332 NA NA N N N N RBM15B high in P 2.4 0.021166004 1.7 752 150 216 324 567 477 362 N N N N N N CEP170 high in P 2.2 0.021172175 1.7 753 13 15 13 25 22 18 N N N N N N MDM4 high in P 2.0 0.021178346 1.7 754 178 177 269 452 394 312 N N N N N N SFRS8 high in P 2.8 0.021205088 1.7 755 237 285 557 817 634 952 N N N N N N PRKDC high in P 3.4 0.021240743 1.7 756 349 553 1101 1640 2109 1228 N N N N N N PSMD1 high in P 2.5 0.021261314 1.7 757 848 1659 1223 4364 3093 1956 N N N N N N FGF5 high in P 2.3 0.021358681 1.7 758 47 30 56 80 97 93 P P N N N N C6orf136 high in P 2.0 0.021378566 1.7 759 110 95 78 168 171 148 N N N N N N TUSC1 high in P 2.5 0.021414221 1.7 760 165 307 178 475 400 409 N N N N N N FUCA1 high in P 3.5 0.021460848 1.7 761 8 34 12 61 48 43 N N N N N N IGF1 high in P 3.2 0.02149376 1.7 762 50 66 105 167 135 133 N N N N N N UBLCP1 high in P 2.7 0.021554786 1.7 763 33 19 13 80 37 54 N N N N N N CTU2 high in P 3.1 0.021575357 1.7 764 85 102 200 247 294 265 NA NA N N N N CCDC115 high in P 2.3 0.021588385 1.7 765 62 74 26 140 95 129 N N N N N N NOC4L high in P 3.2 0.021640496 1.7 766 227 311 598 875 1057 660 N N N N N P TRIM26 high in P 2.0 0.021650096 1.7 767 633 736 1023 1283 1838 1410 N N N N N N PDGFA high in P 3.2 0.021725521 1.7 768 31 87 49 100 119 203 P N N N N N UNC50 high in P 3.8 0.021781747 1.7 769 15 96 39 180 121 138 N N N N N N TROVE2 high in P 1.8 0.021829059 1.7 770 241 355 408 582 723 587 N N N N N N RAGE high in P 2.2 0.02183523 1.7 771 143 103 116 299 267 171 N N N N N N NUDT21 high in P 2.2 0.021846887 1.7 772 234 187 152 432 332 298 N N N N N N PIWIL4 high in P 4.5 0.0218798 1.7 773 4 4 6 10 11 10 N N N N N N SHISA9 high in P 2.0 0.02191477 1.7 774 22 22 19 30 29 28 NA NA N N N N APOL1 high in P 2.4 0.021920941 1.7 775 8 15 16 35 28 24 N N N N N N FAM103A1 high in P 1.5 0.021994995 1.7 776 51 59 55 77 75 76 N N N N N N TUBE1 high in P 3.5 0.022023793 1.7 777 79 53 54 197 247 81 N N N N N N CCDC86 high in P 2.4 0.022078648 1.7 778 132 226 310 409 517 463 N N N N N N PRIC285 high in P 1.7 0.022084819 1.7 779 26 31 38 51 52 51 N N N N N N ZSWIM7 high in P 2.0 0.022139674 1.7 780 32 36 35 69 73 49 N N N N N N GCHFR high in P 3.9 0.022145845 1.7 781 41 43 119 417 216 110 N N N N N N CSF3R high in P 3.8 0.022172586 1.7 782 70 67 199 439 262 216 N N N N N N TOR1B high in P 1.6 0.022182186 1.7 783 83 113 108 154 143 148 N N N N N N LOC100216545 high in P 2.6 0.022195214 1.7 784 44 17 59 107 90 101 NA NA N N N N ABCD1 high in P 3.7 0.022213727 1.7 785 33 62 109 174 119 161 N N N N N N C19orf70 high in P 2.3 0.022273382 1.7 786 291 219 433 638 677 569 N N N N N N ARPC3 high in P 3.7 0.022315894 1.7 787 11 14 39 57 75 38 N N N N N N RNASEH2C high in P 3.0 0.022322065 1.7 788 22 28 47 84 59 56 N N N N N N RHOF high in P 5.5 0.022363206 1.7 789 14 16 50 65 80 52 N N N N N N RFXANK high in P 2.7 0.022470858 1.6 790 241 229 531 1308 1188 513 N N N N N N EAPP high in P 2.5 0.022489372 1.6 791 111 223 125 324 291 243 N N N N N N FRK high in P 1.8 0.022655993 1.6 792 5 8 7 11 12 17 N N N N N N TEAD4 high in P 2.0 0.022675192 1.6 793 150 222 258 337 389 480 N N N N N N METT11D1 high in P 2.7 0.022681363 1.6 794 424 499 839 1195 1103 1142 N N N N N N CYP2R1 high in P 2.9 0.02271359 1.6 795 101 87 174 274 293 191 N N N N N N SBSN high in P 2.4 0.02275336 1.6 796 13 25 35 41 65 53 N N N N N N NEK9 high in P 2.6 0.022797244 1.6 797 39 32 70 117 83 143 N N N N N N PPP1R13L high in P 2.3 0.022903524 1.6 798 1627 712 1233 2620 2270 3716 N N N N N N PIK3CA high in P 2.1 0.023026947 1.6 799 43 56 27 81 68 89 N N N N N N MEG3 high in P 11.4 0.023146942 1.6 800 9 37 29 68 76 271 P N N N N N MIF4GD high in P 2.5 0.023284078 1.6 801 59 59 57 138 182 77 N N N N N N C10orf104 high in P 1.9 0.02329025 1.6 802 NA NA NA NA NA NA N N N N N N UCA1 high in P 3.0 0.023392416 1.6 803 8 12 11 38 29 14 N N N N N N ATP6V1E1 high in P 3.3 0.023423272 1.6 804 64 89 178 248 396 191 N N N N N P ZNF844 high in P 3.5 0.023460299 1.6 805 31 8 11 39 36 43 N N N N N N TRPS1 high in P 2.0 0.023548752 1.6 806 236 233 253 528 466 325 N N N N N N FAIM2 high in P 5.9 0.023564523 1.6 807 7 9 8 71 38 10 N N N N N N CHCHD8 high in P 2.0 0.023618692 1.6 808 56 87 48 93 141 109 N N N N N N CBX5 high in P 2.4 0.023755143 1.6 809 64 61 64 120 110 95 N N N N N N SPSB3 high in P 3.7 0.023761314 1.6 810 1124 629 194 2038 1621 1974 N N N N N N DPY19L3 high in P 1.8 0.02382234 1.6 811 31 31 21 45 43 50 N N N N N N LOC284232 high in P 1.7 0.023869652 1.6 812 301 326 344 539 494 582 NA NA N N N N ACBD6 high in P 3.5 0.023921078 1.6 813 11 19 11 52 39 20 N N N N N N ANKLE1 high in P 2.4 0.023971818 1.6 814 94 58 56 144 108 142 N N N N N N MORF4L1 high in P 2.0 0.02397799 1.6 815 1867 1636 818 3506 3058 2848 N N N N N N EIF2AK2 high in P 2.3 0.023988961 1.6 816 21 51 26 75 66 48 N N N N N N S100A8 high in P 2.9 0.024004046 1.6 817 3 21 21 63 47 50 P N N N N N S100A3 high in P 5.3 0.02403833 1.6 818 14 48 76 234 202 83 N N N N N N LOC729603 high in P 3.0 0.0240589 1.6 819 219 140 74 500 253 331 N N N N N N SPEG high in P 3.7 0.024146668 1.6 820 121 81 258 266 573 427 P P N N N N COX10 high in P 1.8 0.024251577 1.6 821 11 16 22 28 27 32 N N N N N N ABCF1 high in P 2.0 0.024298889 1.6 822 274 294 439 520 666 648 N N N N N N MGC16384 high in P 1.9 0.0243846 1.6 823 36 20 25 45 47 61 NA NA N N N N KRBA2 high in P 2.6 0.024473053 1.6 824 322 197 456 1041 759 541 N N N N N N CYP27C1 high in P 2.4 0.024566991 1.6 825 51 68 116 186 168 114 N N N N N N FAM134B high in P 3.9 0.024619789 1.6 826 92 33 32 194 127 93 N N N N N N GLO1 high in P 2.2 0.02462596 1.6 827 2808 2863 4254 8465 8275 5162 N N N N N N CWorf12 high in P 2.0 0.02463556 1.6 828 81 130 72 146 187 159 N N N N N N CPNE2 high in P 2.2 0.024665044 1.6 829 154 533 570 1036 1131 956 N N N N N N POU2F2 high in P 3.1 0.024689728 1.6 830 11 39 57 98 68 95 N P N N N N DOCK4 high in P 1.6 0.0246959 1.6 831 17 26 21 31 30 29 N N N N N N RAB6A high in P 2.2 0.024769953 1.6 832 21 68 55 127 114 106 N N N N N N GLDC high in P 2.1 0.02480218 1.6 833 5 5 5 7 10 13 P N N N N N ARPC5 high in P 2.4 0.024876234 1.6 834 76 216 129 382 243 275 N N N N N N NDUFA4L2 high in P 4.6 0.024889262 1.6 835 10 8 15 67 40 16 N P N N N N GPR180 high in P 2.3 0.025073025 1.6 836 7 35 32 50 71 47 N N N N N N GRK4 high in P 2.6 0.02508811 1.6 837 5 9 9 12 18 36 N N N N N N HSPB2 high in P 2.8 0.025130623 1.6 838 10 6 6 11 16 37 N N N N N N SHISA4 high in P 5.8 0.02516285 1.6 839 4 42 43 227 113 60 N N N N N N USP8 high in P 2.2 0.025241703 1.6 840 70 147 81 233 206 141 N N N N N N FAM153B high in P 2.4 0.025247874 1.6 841 81 47 113 206 150 161 N N N N N N SCRIB high in P 6.1 0.025308214 1.6 842 220 280 1186 1263 1677 1304 N N N N P N NRM high in P 2.3 0.025317814 1.6 843 34 31 41 127 56 61 N N N N N N COX7B high in P 2.1 0.025323985 1.6 844 66 77 39 104 131 99 N N N N N N EBF3 high in P 2.5 0.025561231 1.6 845 12 12 12 27 21 15 P P N N N N SLC14A1 high in P 2.4 0.025577002 1.6 846 216 108 265 373 428 577 N N N N N N SH3PXD2A high in P 3.4 0.025661341 1.6 847 158 84 102 259 182 318 N N N N N N SERPINB8 high in P 1.6 0.025707968 1.6 848 99 122 108 165 148 193 N N N N N N SF3B2 high in P 2.4 0.025760765 1.6 849 574 538 498 1318 1349 714 N P N N N N LOC285550 high in P 2.7 0.025766936 1.6 850 NA NA NA NA NA NA NA NA N N N N SIDT2 high in P 2.9 0.025808763 1.6 851 302 126 174 442 435 433 N N N N N N HERC5 high in P 2.1 0.025827962 1.6 852 6 8 6 10 16 15 N N N N N N VTI1B high in P 1.6 0.025875274 1.6 853 93 115 97 148 162 134 N N N N N N FBXL8 high in P 3.7 0.025975384 1.6 854 11 42 60 129 150 72 N N N N N N NONO high in P 2.1 0.025995269 1.6 855 1240 524 1368 2916 2768 1955 N N N N N N AP3S1 high in P 2.2 0.02612212 1.6 856 5 9 5 11 18 13 N N N N N N UPP2 high in P 2.2 0.026163261 1.6 857 78 91 91 113 193 181 N N N N N N ZNF350 high in P 2.5 0.026181775 1.6 858 15 8 5 22 14 18 N N N N N N DGKA high in P 1.7 0.026194117 1.6 859 179 166 205 284 334 268 N N N N N N DCP1B high in P 2.9 0.026200288 1.6 860 4 24 18 47 60 27 N N N N N N PATE4 high in P 1.9 0.026318911 1.6 861 21 19 12 30 25 33 NA NA N N N N TRPM7 high in P 2.2 0.026325082 1.6 862 100 121 67 162 144 203 N N N N N N MUT high in P 2.5 0.026342224 1.6 863 9 13 22 35 22 40 N N N N N N JRK high in P 2.7 0.026348396 1.6 864 58 112 151 161 232 255 N N N N N N MTA3 high in P 2.3 0.026395022 1.6 865 303 226 430 703 651 525 N N N N N N NCOR2 high in P 2.1 0.026401193 1.6 866 119 336 354 483 564 592 N N N N N N ZNF407 high in P 1.9 0.026407364 1.6 867 21 34 31 40 40 46 N N N N N N NSMCE1 high in P 9.4 0.026413535 1.6 868 39 49 311 439 384 304 N N N N N N ZNF167 high in P 3.2 0.026482789 1.6 869 6 20 9 21 26 31 N P N N N N ZSCAN16 high in P 3.0 0.026512959 1.6 870 22 26 53 102 88 53 N N N N N N RHEBL1 high in P 2.5 0.026567128 1.6 871 12 11 14 17 27 39 N N N N N N LAT high in P 8.2 0.026596613 1.6 872 20 34 178 204 214 220 N N N N N N NLRP1 high in P 1.7 0.026602784 1.6 873 19 28 29 41 51 35 N N N N N N USP2 high in P 2.0 0.026665181 1.6 874 39 22 30 55 55 54 N N N N N N SLFN13 high in P 1.8 0.026716607 1.6 875 73 53 67 107 118 111 N N N N N N CACHD1 high in P 1.7 0.026731692 1.6 876 37 42 34 50 52 78 N N N N N N INHA high in P 3.3 0.026765291 1.6 877 23 9 3 61 26 29 N N N N N N SLCO4A1 high in P 2.2 0.026787233 1.6 878 9 20 12 53 27 20 P N N N N N FGFBP1 high in P 3.1 0.026802318 1.6 879 220 646 739 830 1714 2176 N N N N N N HMGN4 high in P 1.9 0.026981281 1.6 880 174 235 136 313 356 290 N N N N N N PIP4K2A high in P 2.4 0.026987452 1.6 881 19 42 61 75 101 73 N N N N N N POLDIP3 high in P 2.6 0.027091676 1.6 882 431 262 174 584 549 659 N N N N N N ITGB7 high in P 6.6 0.027107447 1.6 883 15 25 89 78 120 181 N N N N N N LRRC47 high in P 2.4 0.027113618 1.6 884 13 65 71 154 133 95 N N N N N N PCBD1 high in P 3.0 0.027167101 1.6 885 59 23 43 132 125 67 N N N N N N ABCC13 high in P 2.7 0.027213042 1.6 886 23 10 15 32 72 29 N N N N N N KLHL15 high in P 2.9 0.027263782 1.6 887 60 30 34 77 68 95 N N N N N N FXYD5 high in P 3.3 0.027380348 1.6 888 93 458 256 808 730 504 N N N N N N YTHDF2 high in P 2.2 0.027426975 1.6 889 1056 1984 2784 5319 4357 3730 N N N N N N SEC31A high in P 2.0 0.027433146 1.6 890 1808 975 1452 2391 3882 2951 N N N N N N LOC283314 high in P 3.5 0.027448917 1.6 891 66 46 116 253 243 109 NA NA N N N N MRTO4 high in P 2.9 0.027472916 1.6 892 133 247 475 636 1065 528 N N N N N N TGFB1I1 high in P 10.6 0.027522285 1.6 893 65 208 1046 1697 1579 910 N N N N N N KDM2A high in P 2.0 0.027594967 1.6 894 1032 891 847 2319 1762 1451 NA NA N N N N ZC3H12B high in P 1.9 0.027660107 1.6 895 9 10 9 13 15 13 N P N N N N C9orf5 high in P 2.7 0.027714962 1.6 896 70 99 163 247 206 175 N N N N N N TCEA2 high in P 2.7 0.027730732 1.6 897 202 96 307 520 518 423 N N N N N N LOC652276 high in P 1.8 0.027762959 1.6 898 27 28 22 39 47 39 N N N N N N ZNF626 high in P 2.3 0.027775302 1.6 899 16 36 46 68 61 48 N N N N N N ABHD8 high in P 3.7 0.027805472 1.6 900 38 122 105 362 219 128 N N N N N N DECR2 high in P 2.5 0.027839756 1.6 901 229 284 484 594 785 577 N N N N N N MAPKSP1 high in P 2.5 0.027879526 1.6 902 329 167 220 530 420 480 N N N N N N PAK6 high in P 3.6 0.027907639 1.6 903 17 40 45 140 115 44 N N N N N N IQCA1 high in P 2.4 0.027951522 1.6 904 9 10 9 15 19 25 N N N N N N PKP2 high in P 4.1 0.027957693 1.6 905 32 29 79 129 116 71 N N N N N N TRIT1 high in P 1.8 0.027989235 1.6 906 35 39 27 53 70 45 N N N N N N KCNMB1 high in P 3.6 0.028035861 1.6 907 9 15 21 23 39 87 N P N N N N FAM178A high in P 2.7 0.028042032 1.6 908 20 69 60 94 145 90 N N N N N N IDI1 high in P 1.6 0.028112658 1.6 909 323 271 341 507 479 518 N N N N N N TTLL4 high in P 2.5 0.028151056 1.6 910 751 427 377 1414 1079 847 N N N N N N TUBB2B high in P 3.5 0.028162713 1.6 911 115 56 26 144 143 168 N N N N N N AS3MT high in P 2.4 0.02821551 1.5 912 10 15 19 27 24 26 N N N N N N RDH5 high in P 5.6 0.02825528 1.5 913 28 22 107 125 143 123 N N N N N N MET high in P 2.5 0.028291621 1.5 914 22 71 37 83 70 79 N N N N N N RIPK4 high in P 2.5 0.028356761 1.5 915 52 39 45 88 60 109 N N N N N N PROSC high in P 1.8 0.02836636 1.5 916 50 79 74 124 99 121 N N N N N N ATP5J2 high in P 2.8 0.028419844 1.5 917 95 48 165 232 417 187 N N N N N N LOC400043 high in P 3.4 0.028426015 1.5 918 42 113 220 282 343 291 NA NA N N N N LOC286359 high in P 2.4 0.028519953 1.5 919 32 15 15 37 39 40 NA NA N N N N SDF2 high in P 2.4 0.028542581 1.5 920 21 56 36 57 76 101 N N N N N N FAM91A1 high in P 1.7 0.028596064 1.5 921 96 145 111 171 185 191 N N N N N N SIP1 high in P 2.3 0.028633091 1.5 922 22 42 32 83 56 53 N N N N N N FBXO10 high in P 3.9 0.028645433 1.5 923 18 40 90 107 113 123 N N N N N N HMOX1 high in P 4.0 0.028683832 1.5 924 140 802 894 1404 1606 3584 N N N N N N JAGN1 high in P 2.3 0.028848396 1.5 925 138 304 298 653 515 391 N N N N N N SNORD22 high in P 3.7 0.028877194 1.5 926 100 33 25 113 98 229 N N N N N P SMG6 high in P 3.2 0.02891285 1.5 927 84 219 403 606 542 496 N N N N N N C7or54 high in P 2.1 0.028929306 1.5 928 7 8 8 9 15 13 N N N N N N SLC25A26 high in P 2.5 0.028970447 1.5 929 304 214 170 393 437 448 N N N N N N ALG13 high in P 2.6 0.029027359 1.5 930 46 35 31 80 102 48 N P N N N N ATP2A3 high in P 2.0 0.029065757 1.5 931 55 100 122 167 152 217 N N N N N N ACVRL1 high in P 6.6 0.029097984 1.5 932 16 19 19 120 70 19 N N N N N N SLC34A2 high in P 3.6 0.029144611 1.5 933 543 2644 3885 9720 9403 4870 N N N N N N PRR12 high in P 3.3 0.029157639 1.5 934 55 128 213 423 342 198 N N N N N N SLC13A3 high in P 2.1 0.029229635 1.5 935 18 14 25 45 32 30 N N N N N N VCAM1 high in P 2.3 0.029263234 1.5 936 7 15 12 17 23 28 N N N N N N GNAZ high in P 2.2 0.029375 1.5 937 11 32 22 46 39 52 N N N N N N BTN2A2 high in P 3.0 0.029388028 1.5 938 167 99 61 427 168 271 N N N N N N KIAA1632 high in P 1.9 0.029412027 1.5 939 36 58 58 79 65 102 N N N N N N DFFB high in P 2.3 0.029470996 1.5 940 11 14 24 41 29 31 N N N N N N GYS1 high in P 3.1 0.029484024 1.5 941 450 241 532 1526 1543 555 N N N N N N RAB14 high in P 1.8 0.029527222 1.5 942 1157 1882 1740 3428 2642 2769 N N N N P N SHISA5 high in P 2.0 0.029554649 1.5 943 363 686 438 1030 976 714 N N N N N N PLAU high in P 7.9 0.029634874 1.5 944 221 3397 1353 14594 10109 2348 N N N N N N NCBP1 high in P 3.2 0.029810409 1.5 945 88 44 42 99 149 136 N N N N N N NID1 high in P 3.3 0.029934517 1.5 946 15 15 15 53 25 18 P P N N N N ZNF828 high in P 2.1 0.029998971 1.5 947 13 13 12 25 21 16 N N N N N N C13orf33 high in P 3.4 0.030035998 1.5 948 16 22 16 44 21 32 N P N N N N LMTK2 high in P 2.1 0.030129937 1.5 949 334 168 274 607 521 470 N N N N N N NSMCE4A high in P 1.9 0.03019302 1.5 950 4 4 5 14 9 7 N N N N N N LOC147804 high in P 2.4 0.030237589 1.5 951 15 16 25 46 37 26 N N N N N N CAMK2D high in P 2.3 0.030271873 1.5 952 73 46 36 128 70 124 N N N N N N PRDX3 high in P 3.2 0.030337013 1.5 953 1067 368 539 1991 1659 1169 N N N N N N wwOX high in P 3.5 0.030390496 1.5 954 15 20 42 64 58 46 N N N N N N FABP4 high in P 3.7 0.030396668 1.5 955 6 20 17 33 25 101 N N N N N N AKAP11 high in P 2.0 0.030439866 1.5 956 18 27 24 60 35 29 N N N N N N C10orf35 high in P 3.2 0.030457693 1.5 957 142 90 248 531 497 224 N N N N N N NSFL1C high in P 2.6 0.030538604 1.5 958 1161 978 2653 5488 4855 2303 N N N N N N TFIP11 high in P 1.8 0.030574259 1.5 959 164 214 269 387 456 297 N N N N N N LSS high in P 2.3 0.030580431 1.5 960 33 28 31 62 44 59 N N N N N N SCNM1 high in P 6.7 0.030597573 1.5 961 11 17 81 167 148 56 N N N N N N ADAMTS1 high in P 3.0 0.030692883 1.5 962 32 28 28 41 41 59 N N N N N N NIN high in P 1.8 0.030735395 1.5 963 67 72 73 125 97 103 N N N N N N ITGB5 high in P 3.7 0.03076008 1.5 964 793 2008 4089 7176 7228 3969 N N N N N N ACO1 high in P 1.9 0.030824534 1.5 965 49 75 40 89 78 96 N N N N N N LOC254559 high in P 2.2 0.030834133 1.5 966 8 11 9 38 18 14 N P N N N N PDE4D high in P 2.8 0.030846476 1.5 967 17 18 18 33 31 23 N N N N N N MAD2L1BP high in P 3.5 0.030852647 1.5 968 53 25 51 221 70 100 N N N N N N NARG2 high in P 1.7 0.030858818 1.5 969 17 20 23 32 26 28 N N N N N N SOAT1 high in P 2.2 0.030893102 1.5 970 16 41 23 53 46 39 N N N N N N PAG1 high in P 2.6 0.030927386 1.5 971 40 36 37 108 73 46 P P N N N N OXR1 high in P 1.8 0.030965099 1.5 972 114 131 122 168 193 285 N P N N N N MRPS7 high in P 2.1 0.031028867 1.5 973 266 367 477 687 922 551 N N N N N N UBASH3B high in P 3.5 0.031063837 1.5 974 44 132 148 168 216 398 N N N N N N USP13 high in P 2.4 0.031070008 1.5 975 48 107 170 198 216 260 N N N N N N USP54 high in P 6.5 0.031076179 1.5 976 639 141 102 812 509 1363 N N N N N N ENDOG high in P 3.5 0.031140634 1.5 977 108 99 165 513 368 153 N N N N N N C20orf20 high in P 2.0 0.031255828 1.5 978 74 58 51 103 90 102 N N N N N N ADNP high in P 3.8 0.031288741 1.5 979 224 108 84 318 256 304 N N N N N N DSC3 high in P 3.4 0.031343596 1.5 980 34 89 107 260 220 105 P P N N N N CNGB1 high in P 1.8 0.031364852 1.5 981 16 16 11 21 25 22 P N N N N N RBM19 high in P 3.8 0.031390222 1.5 982 105 102 304 422 377 323 N N N N N N DDA1 high in P 2.4 0.031462905 1.5 983 1113 1381 2923 5968 6884 2528 N N N N N N KIAA2018 high in P 1.7 0.031509531 1.5 984 142 160 162 368 224 225 N N N N N N FAM76B high in P 1.8 0.031565071 1.5 985 51 45 27 72 71 65 N N N N N P SYNGR1 high in P 2.3 0.031660381 1.5 986 131 79 203 406 304 232 N N N N N N GPR143 high in P 1.8 0.031698779 1.5 987 3 3 4 7 6 6 P P N N N N RTKN2 high in P 2.1 0.031710436 1.5 988 18 16 24 29 35 42 N N N N N N TGDS high in P 2.3 0.031716607 1.5 989 12 13 20 36 29 27 N N N N N N F12 high in P 2.5 0.031732378 1.5 990 100 48 71 165 187 104 N N N N N N FAM83E high in P 4.7 0.031741978 1.5 991 47 55 218 344 320 177 N N N N N N C4orf52 high in P 2.8 0.031759805 1.5 992 13 11 26 32 35 39 NA NA N N N N HSD11B2 high in P 3.0 0.031839344 1.5 993 57 24 31 54 98 157 N N N N N N CNTFR high in P 8.9 0.031922998 1.5 994 8 8 19 19 19 45 N N N N N P CENPO high in P 2.4 0.031929169 1.5 995 4 29 31 73 63 47 N N N N N N IL1B high in P 3.7 0.031963453 1.5 996 5 5 5 7 14 18 P P N N N N AKNA high in P 4.6 0.031969624 1.5 997 271 313 1350 1987 2027 1157 N N N N N N DAB2 high in P 1.7 0.032025165 1.5 998 52 74 57 87 92 133 N N N N N N AKAP8 high in P 2.3 0.032047792 1.5 999 126 207 287 459 413 307 N N N N N N MAPK14 high in P 2.0 0.032080705 1.5 1000 57 65 47 118 73 101 N N N N N N ASRGL1 high in P 2.7 0.032097161 1.5 1001 53 122 41 174 138 113 N P N N N N SYDE1 high in P 2.0 0.032185614 1.5 1002 21 28 22 63 29 44 N N N N N N EXD2 high in P 1.6 0.032267896 1.5 1003 144 151 171 260 246 194 NA NA N N N N UTS2D high in P 2.0 0.032395433 1.5 1004 7 17 19 38 30 28 N N N N N N PTPN14 high in P 2.2 0.032401604 1.5 1005 17 17 17 21 22 20 N N N N N N NR2C1 high in P 1.8 0.032488001 1.5 1006 17 21 20 25 45 26 N N N N N N NON high in P 3.2 0.032506514 1.5 1007 7 9 11 28 15 20 N N N N N N ERP27 high in P 5.8 0.032516114 1.5 1008 2 3 17 23 27 18 N N N N N N FRY high in P 2.2 0.03272319 1.5 1009 40 47 26 152 73 48 N N N N N N VAC14 high in P 2.3 0.032734846 1.5 1010 16 23 33 44 43 38 N N N N N N MTHFR high in P 1.8 0.032797244 1.5 1011 451 383 541 1107 898 646 N N N N N N TEX264 high in P 2.9 0.032871297 1.5 1012 204 240 716 2032 1164 538 N N N N N N APCDD1 high in P 2.5 0.032882268 1.5 1013 15 20 16 68 36 22 N N N N N N KIAA0892 high in P 2.0 0.032912438 1.5 1014 169 392 415 721 724 551 N N N N N N C20orf27 high in P 3.4 0.032951522 1.5 1015 78 125 235 352 367 233 N N N N N N SMTNL2 high in P 4.5 0.032963865 1.5 1016 3 3 12 59 21 11 N N N N N N UBE2J1 high in P 1.8 0.033009805 1.5 1017 842 610 774 1820 1344 1056 N N N N N N MGC12982 high in P 3.4 0.033035861 1.5 1018 3 5 12 20 16 22 NA NA N N N N ACAP2 high in P 2.0 0.033136657 1.5 1019 27 43 36 42 60 81 N N N N N N SHOX2 high in P 5.2 0.033233338 1.5 1020 6 6 6 37 19 6 P P N N N P BRP44 high in P 2.3 0.033253223 1.5 1021 3 4 4 9 6 14 N N N N N P PLEKHM1P high in P 9.9 0.033295049 1.5 1022 40 28 281 300 355 269 NA NA N N N N DCTD high in P 1.7 0.033393102 1.5 1023 59 71 46 84 107 94 P N N N N N ADRA2C high in P 9.2 0.033448642 1.5 1024 4 17 53 128 124 44 P P N N N N COLQ high in P 2.2 0.033582351 1.5 1025 35 13 26 41 62 53 N N N N N N C9orf45 high in P 2.3 0.033606349 1.5 1026 22 22 37 42 46 73 NA NA N N N N WDR81 high in P 3.8 0.033639262 1.5 1027 31 126 279 686 350 265 NA NA N N N N C8orf46 high in P 3.0 0.033721544 1.5 1028 6 14 28 36 51 38 N N N N N N TMEM185B high in P 1.9 0.033750343 1.5 1029 9 11 10 15 15 18 N N N N N N METTL2A high in P 2.7 0.033791484 1.5 1030 173 71 90 254 221 193 N N N N N N MOXD1 high in P 2.2 0.033803826 1.5 1031 7 7 7 11 10 13 P P N N N N C20orf4 high in P 2.5 0.033849081 1.5 1032 61 58 139 300 233 127 N N N N N N CHD7 high in P 1.9 0.033855252 1.5 1033 87 145 110 144 185 222 N N N N N N C8orf37 high in P 3.0 0.033983475 1.5 1034 41 28 33 261 99 46 N N N N N N PHB2 high in P 3.1 0.033997532 1.5 1035 4056 2754 9298 11952 14955 9259 N N N N N N CHEK1 high in P 2.4 0.034017759 1.5 1036 26 51 45 110 85 53 N N N N N N PTPN6 high in P 3.6 0.034060957 1.5 1037 42 92 183 492 278 153 N N N N N N PABPN1 high in P 2.3 0.034067128 1.5 1038 1041 570 743 1310 1573 1778 N N N N N N CWF19L2 high in P 2.6 0.034113069 1.5 1039 57 71 25 142 97 78 N N N N N N NRN1 high in P 2.4 0.034143239 1.5 1040 5 10 7 16 12 21 P P N N N N HLA-DRB5 high in P 17.0 0.034289975 1.5 1041 3 292 29 1046 418 133 N N N N N N SCAPER high in P 2.2 0.034361286 1.5 1042 18 18 24 29 28 36 N N N N N N THOC2 high in P 1.7 0.034457282 1.5 1043 30 42 29 55 59 42 N N N N N N FIP1L1 high in P 2.5 0.034463453 1.5 1044 5 32 37 65 55 65 N N N N N N SHARPIN high in P 7.7 0.034469624 1.5 1045 78 243 950 1694 1485 699 N N N N N N SYNE2 high in P 2.2 0.03453065 1.5 1046 134 239 138 376 232 338 N N N N N N KRT71 high in P 2.8 0.034544364 1.5 1047 11 5 7 11 24 55 N N N N N N LDLR high in P 2.9 0.034582076 1.5 1048 4198 3717 9555 11174 10997 11576 N N N N N N ZNF37A high in P 1.9 0.034657501 1.5 1049 29 52 41 50 68 72 N N N N P N EIF2AK4 high in P 2.1 0.034678072 1.5 1050 18 40 24 54 42 37 N N N N N N C12orf34 high in P 2.1 0.034693157 1.5 1051 8 13 18 23 28 22 N N N N N N CEBPD high in P 2.5 0.034699328 1.5 1052 1983 3003 6209 7677 7243 7347 N N N N N N NOG high in P 2.6 0.03477681 1.5 1053 6 6 6 9 12 34 P P N N N N DES high in P 1.9 0.034806295 1.5 1054 4 13 10 16 23 23 N N N N N N DDRGK1 high in P 1.9 0.034909147 1.5 1055 178 289 218 523 388 308 N N N N N N LOC643008 high in P 2.1 0.034931775 1.5 1056 19 15 15 24 28 40 N N N P N N BMPR1A high in P 1.9 0.034968801 1.5 1057 53 105 57 158 135 96 N N N N N N DCAF6 high in P 2.1 0.034996229 1.5 1058 76 63 48 107 93 151 NA NA N N N N SNX10 high in P 2.2 0.035035313 1.5 1059 16 26 7 49 36 27 N N N N N N MAPK1 high in P 2.1 0.035049712 1.5 1060 34 78 68 80 97 133 N N N N N N H1FO high in P 6.1 0.035122394 1.5 1061 764 306 178 6877 879 897 N N N N N N RNF160 high in P 2.3 0.035143651 1.5 1062 81 59 47 107 88 118 NA NA N N N N BMP2 high in P 2.4 0.035149822 1.5 1063 81 68 30 194 124 93 P N N N N N PTGER2 high in P 1.8 0.035191648 1.5 1064 6 9 11 20 19 12 N N N N N N PANX2 high in P 2.2 0.035210162 1.5 1065 47 63 41 105 115 60 N N N N N P CSPP1 high in P 1.8 0.035247189 1.5 1066 53 51 48 65 96 82 N N N N N N RNF123 high in P 2.1 0.035310957 1.5 1067 187 220 360 482 528 372 N N N N N N FAM55C high in P 2.0 0.035317128 1.5 1068 153 91 144 296 218 212 N N N N N N ZNF222 high in P 2.2 0.0353233 1.5 1069 14 4 8 20 13 25 N N N N N N C1GALT1C1 high in P 3.4 0.035367869 1.5 1070 3 21 9 45 20 31 N N N N N N EIF4E3 high in P 1.8 0.035380211 1.5 1071 22 38 26 38 44 50 N N N N N N FTL high in P 2.0 0.03540181 1.5 1072 7268 8189 12575 25579 18307 12782 N N N N N N FBXW5 high in P 4.0 0.035496092 1.4 1073 1731 1055 4435 7056 7774 3959 N N N N N N LIMS3 high in P 2.5 0.035514605 1.4 1074 50 10 24 88 57 62 N N N N N N TYW3 high in P 1.8 0.035611286 1.4 1075 40 91 69 136 109 96 N N N N N N IKBKB high in P 1.8 0.035651056 1.4 1076 290 264 252 464 403 580 N N N N N N MRPS35 high in P 1.9 0.035716196 1.4 1077 190 202 269 376 359 320 N N N N N N SLC31A1 high in P 2.5 0.035722367 1.4 1078 25 32 31 59 33 59 N N N N N N RPL12 high in P 2.8 0.035753566 1.4 1079 26399 10589 17402 30861 50250 44261 N N N N N N C6orf48 high in P 2.0 0.035764194 1.4 1080 769 454 548 909 1013 1516 N N N N N N AKAP5 high in P 2.0 0.035807392 1.4 1081 7 9 11 20 12 18 N N N N N N PCDH1 high in P 2.0 0.035822477 1.4 1082 170 215 349 471 464 348 N N N N N N LRWD1 high in P 1.9 0.035828648 1.4 1083 25 79 71 121 107 125 N N N N N N DCN high in P 4.1 0.035923958 1.4 1084 31 31 31 45 40 31 N P N N N N ATF7IP high in P 1.9 0.035958928 1.4 1085 19 26 21 34 45 27 N N N N N N VANGL2 high in P 2.0 0.035997326 1.4 1086 105 99 99 328 172 131 N N N N N N FBN2 high in P 1.8 0.036015839 1.4 1087 9 9 9 14 12 12 N N N N N N RAB3IP high in P 1.9 0.036070008 1.4 1088 43 108 93 160 113 107 N N N N N N EXTL3 high in P 7.4 0.036149547 1.4 1089 122 369 1394 2564 2242 1032 N N N N N N CD74 high in P 2.6 0.036176289 1.4 1090 222 158 128 453 594 222 N N N N N N MX2 high in P 2.1 0.036312054 1.4 1091 9 11 14 20 18 20 N N N N N N C14orf73 high in P 3.1 0.036318225 1.4 1092 2 18 8 49 30 18 N N N N N N ST7L high in P 2.8 0.036344281 1.4 1093 12 39 46 84 86 49 N N N N N N FLT1 high in P 1.7 0.036375823 1.4 1094 28 40 32 46 41 46 P P N N N N DSE high in P 2.4 0.036442334 1.4 1095 32 34 18 57 38 62 N N N N N N C16or54 high in P 1.8 0.036570557 1.4 1096 37 17 28 62 48 52 N N N N N N C3orf1 high in P 2.7 0.036640496 1.4 1097 185 95 84 288 260 196 N N N N N N RUVBL1 high in P 1.8 0.036646668 1.4 1098 36 71 49 84 78 81 N N N N N N KRT5 high in P 2.9 0.036751577 1.4 1099 1288 3829 3293 3939 7495 14672 N N N N N N PIK3C2B high in P 1.9 0.036773519 1.4 1100 26 29 21 46 33 34 N N N N N N PDP1 high in P 1.7 0.03677969 1.4 1101 17 24 22 36 33 26 NA NA N N N N EFNA5 high in P 4.3 0.036785861 1.4 1102 32 198 73 322 257 158 N N N N N N HBS1L high in P 1.8 0.036792032 1.4 1103 65 45 71 110 102 127 N N N N N N FLJ20184 high in P 1.8 0.036798204 1.4 1104 NA NA NA NA NA NA N N N N N N CSor75 high in P 2.5 0.036893513 1.4 1105 NA NA NA NA NA NA N N N N N N ZNF518B high in P 2.7 0.036911341 1.4 1106 32 22 27 53 60 36 P P N N N N PPAP2B high in P 5.4 0.036951111 1.4 1107 60 778 222 1648 962 724 N N N N N N SNX8 high in P 2.2 0.037066991 1.4 1108 168 133 219 341 440 233 N N N N N N IFITM2 high in P 4.2 0.037115675 1.4 1109 241 903 697 4035 1618 860 N N N N N N LRCH4 high in P 2.3 0.037142416 1.4 1110 368 343 937 1654 1538 723 N N N N N N STAC high in P 2.8 0.037186986 1.4 1111 5 12 5 12 15 34 P N N N N N MDK high in P 2.1 0.037232241 1.4 1112 967 517 1435 1856 2080 2331 P N N N N N RPS19BP1 high in P 3.8 0.037270639 1.4 1113 72 116 248 367 422 211 N N N N N N LIG4 high in P 1.6 0.037322065 1.4 1114 101 112 89 195 130 135 N N N N N N CBS high in P 4.4 0.037335093 1.4 1115 101 162 120 479 583 146 N N N N N N MRPS25 high in P 2.3 0.037341264 1.4 1116 220 101 165 302 334 311 N N N N N N TSPYL2 high in P 2.4 0.037424918 1.4 1117 2051 703 1691 4972 2342 4236 N P N N N N XPO7 high in P 2.4 0.037436574 1.4 1118 26 23 28 49 65 33 N N N N N N CEP63 high in P 1.6 0.037516799 1.4 1119 22 35 32 44 43 37 N N N N N N ZNF623 high in P 1.6 0.037645708 1.4 1120 44 34 45 61 67 68 N N N N N N TAL1 high in P 2.0 0.037750617 1.4 1121 6 7 7 18 9 12 P P N N N N HTR7P high in P 2.7 0.037836327 1.4 1122 NA NA NA NA NA NA N N N N N N TGFBI high in P 1.9 0.037852098 1.4 1123 13 15 16 37 19 22 P N N N N N SAP30L high in P 2.1 0.037858269 1.4 1124 26 56 38 72 65 50 N N N N N N LOC401093 high in P 1.7 0.037941923 1.4 1125 41 42 48 61 57 63 NA NA N N N N GINS1 high in P 3.9 0.037954951 1.4 1126 20 11 31 28 65 59 N N N N N N HOXC11 high in P 2.2 0.037961122 1.4 1127 2 6 7 12 19 16 P P N N N N NAGK high in P 2.1 0.03802489 1.4 1128 66 161 101 195 166 209 N N N N N N ACCN3 high in P 5.3 0.038090716 1.4 1129 39 22 163 135 186 256 N N N N N N SLC25A37 high in P 2.3 0.038172998 1.4 1130 752 1900 770 1697 2675 3129 N N P N N N KLC1 high in P 3.6 0.038231967 1.4 1131 1091 718 3585 4153 4170 4084 N N N N N N SYT8 high in P 6.9 0.038423272 1.4 1132 21 19 34 31 86 548 N N N N N N GLRX high in P 2.2 0.038632405 1.4 1133 634 390 321 749 740 965 N N N N N N NUDT4 high in P 4.7 0.03866669 1.4 1134 45 101 226 578 364 167 N N N N N N ADAM15 high in P 3.0 0.038704402 1.4 1135 103 128 294 308 299 435 N N N N N N GPAT2 high in P 2.1 0.038749657 1.4 1136 11 19 20 27 43 26 NA NA N N N N EIF3J high in P 2.1 0.038755828 1.4 1137 445 859 1259 1383 2188 1755 N N N N N N TYMP high in P 3.0 0.038893651 1.4 1138 1968 4763 6110 18330 9400 6361 N N N N N N MUC20 high in P 2.2 0.038899822 1.4 1139 29 31 35 83 55 42 N N N N N N CCND3 high in P 2.3 0.038935477 1.4 1140 223 855 551 1351 902 1241 N N N N N N LRRC27 high in P 2.8 0.038986903 1.4 1141 171 366 641 900 953 627 N N N N N P ALDH1L2 high in P 1.9 0.039036958 1.4 1142 35 35 46 62 64 48 N P N N N N FBX025 high in P 1.8 0.039148039 1.4 1143 79 106 62 145 151 100 N N N N N N CTSL1 high in P 2.9 0.039163124 1.4 1144 33 92 35 138 78 87 N N N N N N ZNF512 high in P 2.3 0.039186437 1.4 1145 99 47 41 118 85 196 N N N N N N FAM40B high in P 2.1 0.039239235 1.4 1146 20 19 39 52 47 42 N N N N N N GPT2 high in P 2.0 0.039318774 1.4 1147 72 95 167 277 309 142 N N N N N N CENPM high in P 2.9 0.03935443 1.4 1148 7 11 28 40 33 33 N N N N N N POLD4 high in P 2.0 0.039470996 1.4 1149 180 164 113 273 272 204 N N N N N N SMC3 high in P 2.8 0.039514879 1.4 1150 54 57 53 126 154 61 N N N N N N SLC22A23 high in P 1.9 0.039599904 1.4 1151 136 185 243 318 270 324 N N N N N N Clorf 16 high in P 1.6 0.03962596 1.4 1152 103 109 98 165 158 123 N N N N N N NUDT9 high in P 2.0 0.039678758 1.4 1153 6 7 6 10 22 11 N N N N N N PAR5 high in P 2.7 0.03979121 1.4 1154 50 32 61 74 164 88 N N N N N N SLC25A38 high in P 2.2 0.040047655 1.4 1155 61 183 217 289 348 319 N N N N N N TTC1 high in P 1.8 0.040081939 1.4 1156 153 175 122 272 288 189 N N N N N N ACOT7 high in P 3.4 0.040147765 1.4 1157 116 266 575 739 770 599 N N N N N N HSPBP1 high in P 2.0 0.040164907 1.4 1158 218 259 360 630 348 548 N N N N N N SDK2 high in P 2.6 0.040193705 1.4 1159 23 26 23 31 28 63 NA NA N N N N LOC344967 high in P 2.0 0.040206048 1.4 1160 238 128 190 371 394 271 NA NA N N N N DNM1P35 high in P 1.7 0.040332213 1.4 1161 14 18 17 26 19 25 NA NA N N N N RIT1 high in P 2.1 0.04034387 1.4 1162 234 169 106 307 291 360 N N N N N N PHB high in P 3.9 0.040417924 1.4 1163 16 61 127 174 218 129 N N N N N N IRF5 high in P 2.2 0.040451522 1.4 1164 73 170 220 308 273 324 P N N N N N ZNF497 high in P 2.5 0.040461122 1.4 1165 6 6 6 15 11 9 N N P N N N ZNF500 high in P 2.1 0.040508434 1.4 1166 7 24 24 47 38 28 N N N N N N DAK high in P 2.7 0.040640771 1.4 1167 88 148 235 321 330 225 N N N N N N THEM4 high in P 2.1 0.040683969 1.4 1168 28 47 46 118 83 49 N N N N N N RAPGEFL1 high in P 1.7 0.040699054 1.4 1169 43 61 61 81 112 72 N N N N N N FANCC high in P 2.2 0.040712767 1.4 1170 56 38 62 118 154 63 N N N N N N NAA20 high in P 2.6 0.040862932 1.4 1171 133 249 101 326 322 237 NA NA N N N N ZNRF1 high in P 2.0 0.040869103 1.4 1172 324 437 339 834 474 603 N N N N N N MTMR15 high in P 2.5 0.0409363 1.4 1173 107 60 54 124 157 116 N N N N N N SLC25A46 high in P 2.4 0.040985669 1.4 1174 10 36 21 44 77 30 N N N N N N SURF2 high in P 2.4 0.041054238 1.4 1175 7 6 11 15 31 16 N N N N N N RGS16 high in P 2.2 0.041060409 1.4 1176 15 64 36 69 69 69 N N N N N N ICAM1 high in P 2.6 0.041126234 1.4 1177 566 1686 754 1846 1682 3435 N N N N N N HINT3 high in P 3.7 0.041264742 1.4 1178 148 65 24 188 201 157 N N N N N N IL10RA high in P 2.3 0.041296969 1.4 1179 6 6 7 14 9 10 P P N N N N GDI1 high in P 4.8 0.041569871 1.4 1180 368 78 119 376 434 517 N N P N N N TMEM43 high in P 2.9 0.041790661 1.4 1181 261 330 800 821 1094 832 N N N N N N SETDB1 high in P 2.1 0.041948368 1.4 1182 87 139 161 241 243 175 N N N N N N PTPN23 high in P 3.8 0.042180129 1.4 1183 650 656 3076 4719 4087 2117 N N N N N N SLC16A13 high in P 3.9 0.0421863 1.4 1184 1 18 27 96 70 29 N N N N N N NCRNA00081 high in P 1.8 0.042192471 1.4 1185 6 8 6 10 15 11 N N N N N N METTL7A high in P 2.3 0.042243897 1.4 1186 200 124 127 314 262 228 N N N N N N PPP2CB high in P 1.9 0.042250069 1.4 1187 3222 2155 3089 3906 6120 7060 N N N N N N ZMAT3 high in P 2.5 0.042262411 1.4 1188 24 143 112 250 166 299 N N N N N N RPP30 high in P 2.7 0.042295324 1.4 1189 15 19 33 44 46 31 N P N N N N HELB high in P 3.1 0.042301495 1.4 1190 8 10 10 29 11 27 N N N N N N MKLN1 high in P 1.8 0.042322751 1.4 1191 354 181 377 538 588 639 N N N N N N PIP5K1C high in P 2.1 0.042376234 1.4 1192 54 271 199 354 365 380 N N N N N N ST3GAL1 high in P 2.2 0.0424976 1.4 1193 204 705 483 961 1133 841 N N N N N N PUS10 high in P 1.8 0.04256274 1.4 1194 10 16 13 16 20 26 N N N N N N SEMA6B high in P 1.9 0.042600453 1.4 1195 13 17 18 113 27 27 N N N N N N IPP high in P 2.0 0.04271359 1.4 1196 19 18 28 52 45 30 N N N N N N CXCL3 high in P 4.0 0.042751988 1.4 1197 25 17 13 19 54 68 N N N N N N HN1L high in P 1.8 0.042782844 1.4 1198 861 1378 1293 2260 1796 2130 N N N N N N TMEM100 high in P 2.2 0.042806843 1.4 1199 5 5 5 9 8 11 N P N N N N PECR high in P 3.7 0.042813014 1.4 1200 14 7 19 75 39 18 N N N N N N TRIM8 high in P 2.5 0.042826042 1.4 1201 287 694 706 1678 876 999 N N N N N N LAMB3 high in P 2.2 0.042968664 1.4 1202 125 348 267 436 518 595 N N N N N N NCF4 high in P 9.4 0.042978264 1.4 1203 3 45 197 455 315 111 P N N N N N TSPAN31 high in P 2.7 0.043039975 1.4 1204 108 56 93 261 131 140 P P N N N N NCRNA00174 high in P 2.0 0.043207282 1.4 1205 13 18 13 28 22 18 NA NA N N N N YRDC high in P 1.8 0.043605664 1.4 1206 128 141 90 244 222 151 N N N N N N ST3GAL5 high in P 2.4 0.043611835 1.4 1207 10 10 12 25 23 16 N N N N N N DCPS high in P 3.1 0.04368726 1.4 1208 40 82 137 295 272 102 N N N N N N GDF11 high in P 1.8 0.043849767 1.4 1209 10 14 13 28 21 16 N N N N N N FAM117B high in P 2.0 0.043855938 1.4 1210 27 23 17 45 29 31 N N N N N N PLK1S1 high in P 4.0 0.043995132 1.4 1211 6 6 8 24 12 10 NA NA N N N N ZNF586 high in P 2.0 0.044017759 1.4 1212 19 13 20 22 32 38 N N N N N N ZNF436 high in P 1.7 0.04402393 1.4 1213 42 54 57 78 69 85 N N N N N N PPP2R5A high in P 2.3 0.044078099 1.4 1214 98 213 101 258 201 253 N N N N N N FIGN high in P 2.9 0.04408427 1.4 1215 6 6 6 10 16 6 N N N N N N SLED1 high in P 4.3 0.044222778 1.4 1216 86 2 38 269 158 90 N N N N N N HDHD2 high in P 2.0 0.04422895 1.4 1217 16 35 27 41 44 61 N N N N N N RCN3 high in P 2.6 0.04423992 1.4 1218 13 17 15 55 18 26 N N N N N N RARRES1 high in P 3.7 0.044260491 1.4 1219 21 144 46 418 223 83 N N N N N N KCTD18 high in P 3.0 0.044294089 1.4 1220 51 56 19 135 69 65 N N N N P N ACBD3 high in P 1.6 0.044303689 1.4 1221 256 263 188 379 369 327 N N N N N N TFRC high in P 3.2 0.044413398 1.4 1222 255 114 86 230 355 370 N N N N N N WDR1 high in P 1.8 0.044419569 1.4 1223 2362 3332 2237 4780 4838 4245 N N N N N N TIMM17A high in P 1.8 0.044519679 1.4 1224 1050 882 1248 2047 2198 1401 N N N N N N YTHDF3 high in P 2.1 0.04452585 1.4 1225 207 191 98 337 249 336 N N N N N N ANGPTL2 high in P 3.0 0.044538193 1.4 1226 17 21 20 37 24 30 N N N N N N PIK3CG high in P 4.1 0.044779896 1.3 1227 11 7 8 30 22 10 N N N N N N PSD high in P 2.7 0.044841264 1.3 1228 6 7 14 15 24 20 P P N N N N CYTSB high in P 1.5 0.044957145 1.3 1229 6 12 10 14 16 13 NA NA N N N N ZC3HAV1 high in P 1.9 0.044988686 1.3 1230 45 92 60 129 80 97 N N N N N N UGGT1 high in P 2.3 0.044994857 1.3 1231 56 62 45 99 118 69 NA NA N N N N POM121L8P high in P 3.7 0.04507234 1.3 1232 29 28 82 99 89 78 NA NA N N N N HEATR2 high in P 1.9 0.045094281 1.3 1233 26 34 14 51 35 45 N N N N N N PAOX high in P 2.0 0.04511828 1.3 1234 4 8 5 10 31 10 N N N N N N MVK high in P 2.6 0.045124451 1.3 1235 119 95 216 380 301 203 N N N N N N CD164L2 high in P 2.7 0.045174506 1.3 1236 29 11 58 72 58 129 N N N N N N SMOC1 high in P 2.9 0.04521359 1.3 1237 7 28 44 99 63 40 P N N N N N SAA1 high in P 3.6 0.045402839 1.3 1238 2981 16504 6016 34767 17846 11326 N N N N N N RANBP2 high in P 1.9 0.045461807 1.3 1239 62 72 47 81 112 86 N N N N N N RASAL1 high in P 2.3 0.045540661 1.3 1240 73 27 51 130 113 71 N N N N N N TBP high in P 3.0 0.045566031 1.3 1241 34 56 131 179 125 135 N N N N N N ZNF767 high in P 4.1 0.045572202 1.3 1242 20 78 179 175 237 222 N N N N N N APOBEC3F high in P 1.7 0.045723738 1.3 1243 59 62 94 111 141 108 N N N N N N JKAMP high in P 3.1 0.045757337 1.3 1244 25 110 40 166 106 92 NA NA N N N N PDDC1 high in P 1.8 0.045827962 1.3 1245 43 82 88 94 114 132 N N N N N N DDN high in P 1.8 0.045834133 1.3 1246 11 8 9 16 13 24 P N N N N N MBD4 high in P 1.8 0.045845104 1.3 1247 507 408 499 989 716 626 N N N N N P C1orf21 high in P 2.7 0.045958928 1.3 1248 484 239 278 514 624 679 N N N N N N TMEM9B high in P 2.7 0.045986355 1.3 1249 69 193 77 262 223 171 N N N N N N RNF144A high in P 1.8 0.046106349 1.3 1250 13 24 16 46 22 27 N N N N N N CSTB high in P 2.0 0.04611732 1.3 1251 364 374 210 696 575 435 N N N N N N ADAT3 high in P 3.4 0.046148176 1.3 1252 117 142 454 635 540 369 N N N N N N ZNF484 high in P 2.0 0.046227715 1.3 1253 4 6 4 12 7 10 N N N N N N RPAP2 high in P 1.8 0.046240743 1.3 1254 59 53 58 76 104 91 N N N N N N C15orf40 high in P 1.6 0.046294227 1.3 1255 33 35 36 51 71 47 N N N N N N C8orf41 high in P 1.8 0.046329196 1.3 1256 13 61 46 88 78 79 N N N N N N FBXL18 high in P 1.7 0.046364166 1.3 1257 60 50 67 94 97 122 N N N N N N SOCS6 high in P 1.8 0.046380623 1.3 1258 47 42 49 81 65 77 N N N N N N SLCO3A1 high in P 3.2 0.046499246 1.3 1259 22 157 66 193 143 198 P N N N N N AVEN high in P 2.4 0.046578099 1.3 1260 3 15 7 18 34 14 N N N N N N TCIRG1 high in P 2.3 0.046641868 1.3 1261 226 477 581 1174 955 558 N N N N N N CXorf36 high in P 2.1 0.046669981 1.3 1262 25 22 25 41 30 37 N P N N N N RNF145 high in P 2.5 0.046685752 1.3 1263 979 559 453 1308 1119 1385 N N N N N N ZCCHC17 high in P 2.2 0.046740606 1.3 1264 312 435 296 906 704 438 N N N N N N ORC4L high in P 2.0 0.046853744 1.3 1265 33 25 30 43 38 57 N N N N N N ZBTB40 high in P 2.3 0.046859915 1.3 1266 93 139 217 256 262 250 N N N N N N LOC388692 high in P 1.6 0.046894199 1.3 1267 101 109 118 173 145 160 NA NA N N N N LRP1 high in P 1.9 0.046994995 1.3 1268 64 78 86 101 92 93 N N N N N N CCNL1 high in P 2.0 0.047162987 1.3 1269 708 492 436 921 848 1214 N N N N N N REM1 high in P 2.3 0.047210985 1.3 1270 2 7 9 15 14 23 N N N N N N C5orf24 high in P 1.7 0.04724664 1.3 1271 39 52 35 75 67 48 N N N N N N POLR2J4 high in P 2.2 0.047345378 1.3 1272 17 22 17 43 29 22 N N N N N N GOPC high in P 1.9 0.047368692 1.3 1273 17 61 37 56 61 86 N N N N N N SOD2 high in P 1.6 0.047424918 1.3 1274 406 485 540 847 695 685 N N N N N N PPP1R3A high in P 3.4 0.047501714 1.3 1275 895 642 300 1047 1016 3142 N N N N N N ANKRD17 high in P 2.3 0.047570968 1.3 1276 122 303 180 371 330 337 N N N N N N LOC90784 high in P 2.3 0.047752674 1.3 1277 15 32 34 66 51 33 NA NA N N N N TLN2 high in P 2.0 0.047777359 1.3 1278 63 40 47 113 76 69 N N N N N N VILL high in P 2.3 0.047841127 1.3 1279 39 31 60 102 109 57 N N N N N N KHNYN high in P 1.8 0.04789941 1.3 1280 242 527 529 691 859 669 NA NA N N N N MAFF high in P 1.9 0.047919295 1.3 1281 436 126 414 658 707 780 N N N N N N CNNM3 high in P 2.2 0.048000206 1.3 1282 20 74 52 108 107 64 N N N N N N EFHC1 high in P 2.3 0.048074945 1.3 1283 64 58 121 202 172 99 N N N N N N MRPL16 high in P 1.8 0.048090716 1.3 1284 163 139 179 335 296 194 N P N N N N YTHDC1 high in P 3.2 0.048096887 1.3 1285 2133 810 608 2480 2165 3027 N N N N N N CYP1A1 high in P 7.0 0.048227167 1.3 1286 14 44 25 200 116 27 P P N N N N CLDN4 high in P 6.5 0.048358132 1.3 1287 4341 766 280 20015 1394 10767 N N N N N N HLA-G high in P 3.7 0.0484315 1.3 1288 5 5 6 28 21 5 P P P N P N GATSL3 high in P 1.9 0.048528867 1.3 1289 97 60 141 217 175 157 NA NA N N N N DHX33 high in P 2.0 0.048568637 1.3 1290 13 33 20 51 31 30 N N N N N N LONRF2 high in P 2.9 0.04859675 1.3 1291 37 32 31 55 51 45 N N N N N N RCCD1 high in P 1.8 0.048648176 1.3 1292 18 30 36 39 46 51 N N N N N N L2HGDH high in P 1.7 0.048718801 1.3 1293 199 146 172 276 253 313 N N N N N N RPL23AP82 high in P 1.9 0.048735258 1.3 1294 2 2 4 6 5 8 NA NA N N N N MBP high in P 1.9 0.04887308 1.3 1295 66 126 96 128 167 173 N N N N N N TREX1 high in P 2.0 0.048893651 1.3 1296 141 98 126 266 184 172 N N N N N N FAM32A high in P 2.2 0.048908736 1.3 1297 282 573 562 1192 993 621 N N N N N N SEPW1 high in P 2.1 0.048925878 1.3 1298 722 1299 598 1513 1510 1372 N N N N N N APOD high in P 2.2 0.049015016 1.3 1299 953 558 220 1937 1066 1074 N N N N N N DCBLD2 high in P 1.8 0.049041072 1.3 1300 31 81 47 92 64 92 N N N N N N HGFAC high in P 2.0 0.049225521 1.3 1301 15 31 13 43 26 43 N N N N N N MRPL48 high in P 2.4 0.049231692 1.3 1302 121 77 161 307 300 151 N N N N N N PPP40 high in P 3.9 0.04930986 1.3 1303 39 27 108 146 168 81 N N N N N N RAB11FIP5 high in P 1.6 0.049486766 1.3 1304 59 65 70 121 91 81 N N N N N N CILP high in P 1.9 0.04952585 1.3 1305 17 20 22 24 29 33 N N N N N N PIGY high in P 1.6 0.049558077 1.3 1306 124 135 117 204 198 158 N N N N N N AKIRIN2 high in P 2.3 0.049571105 1.3 1307 1090 494 618 1247 1330 1563 N N N N N N ANKFY1 high in P 1.7 0.049612246 1.3 1308 118 328 335 459 509 459 N N N P N N CHD3 high in P 1.7 0.049645159 1.3 1309 575 424 806 936 926 1271 N N N N N N CLN5 high in P 2.2 0.049684243 1.3 1310 40 123 72 154 113 142 N N N N N N MYH14 high in P 1.9 0.049774753 1.3 1311 454 629 907 1104 1307 993 N N N N N N EHMT2 high in P 2.8 0.049780924 1.3 1312 165 119 341 699 463 288 N N N N N N PLXNB1 high in P 1.8 0.049813151 1.3 1313 713 861 1344 1400 1704 1898 N N N N N N TTC4 high in P 1.5 0.049822751 1.3 1314 19 24 21 38 28 30 N N N N N N STARD7 high in P 3.7 0.049859092 1.3 1315 156 48 61 176 214 178 N N N N N N BOP1 high in P 2.4 0.049865263 1.3 1316 88 177 107 139 310 333 N N N N N N

TABLE 17 Enriched GeneGo Pathway Maps for DMRs in Promoter and Gene Body in CD44+ Cells Promoter Genebody hypermethylated hyper methylated Pathway maps Nulliparous Parous Nulliparous Parous Stem cells_H3K9 demethylases in pluripotency maintenance of stem cells 7.04E−05 Development_VEGF signaling and activation 7.82E−05 Development_VEGF signaling via VEGFR2 - generic cascades 9.77E−05 HCV-dependent cytoplasmic signaling leading to HCC 2.18E−02 1.62E−04 2.30E−03 Stem cells_Cooperation between Hedgehog, IGF-2 and HGF signaling pathways 3.41E−02 3.20E−04 3.76E−03 1.64E−02 in medulloblastoma stem cells HBV signaling via protein kinases leading to HCC 5.07E−04 4.90E−02 Cytoskeleton remodeling_Alpha-1A adrenergic receptor-dependent inhibition of 9.44E−04 PI3K Development_FGF2-dependent induction of EMT 1.10E−03 1.64E−02 Signal transduction_PTEN pathway 1.30E−03 1.04E−02 3.24E−02 Development_TGF-beta-dependent induction of EMT via RhoA, PI3K and ILK. 3.49E−03 1.30E−03 Development_Leptin signaling via PI3K-dependent pathway 1.41E−03 3.37E−02 IL-6 signaling in multiple myeloma 1.65E−03 1.24E−02 Stem cells_Insulin, IGF-1 and TNF-alpha in brown adipocyte differentiation 2.20E−03 Regulation of lipid metabolismjnsulin regulation of fatty acid methabolism 2.31E−03 1.15E−02 Immune response_BCR pathway 2.36E−03 Muscle contraction_Oxytocin signaling in uterus and mammary gland 3.47E−03 Regulation of lipid metabolism_RXR-dependent regulation of lipid metabolism 3.64E−03 via PPAR, RAR and VDR Unsaturated fatty acid biosynthesis 3.91E−03 Development_Regulation of epithelial-to-mesenchymal transition (EMT) 4.38E−03 3.61E−03 Cell cycle_Role of Nek in cell cycle regulation 4.38E−03 3.96E−02 Stem cells_Self-renewal and pluripotency maintenance of human embryonic 4.79E−03 stem cells Apoptosis and survival_Role of CDK5 in neuronal death and survival 5.21E−03 4.42E−02 Stem cells_Role of PKR1 and ILK in cardiac progenitor cells 5.21E−03 1.84E−02 Immune response_Oncostatin M signaling via MAPK in mouse cells 5.65E−03 4.66E−02 Immune response_Oncostatin M signaling via MAPK in human cells 6.61E−03 Stem cells_Early embryonal hypaxial myogenesis 4.93E−02 6.61E−03 2.16E−02 Apoptosis and survival_Ceramides signaling pathway 7.13E−03 6.14E−03 Immune response_Human NKG2D signaling 7.13E−03 6.14E−03 Transcription_Role of AP-1 in regulation of cellular metabolism 7.13E−03 Development_Gastrin in differentiation of the gastric mucosa 7.13E−03 Stem cells_FGF signaling in pancreatic and hepatic differentiation of embryonic 8.22E−03 stem cells Stem cells_FGF2-induced self-renewal of adult neural stem cells 8.22E−03 Immune response_Murine NKG2D signaling 9.41E−03 8.12E−03 Apoptosis and survival_BAD phosphorylation 9.41E−03 8.12E−03 Regulation of lipid metabolism_PPAR regulation of lipid metabolism 9.41E−03 Development_A2A receptor signaling 1.00E−02 8.66E−03 Apoptosis and survival_Anti-apoptotic action of Gastrin 1.00E−02 Immune response_IL-1 signaling pathway 1.07E−02 8.96E−04 Development_Flt3 signaling 1.07E−02 Development_Thrombopoietin-regulated cell processes 1.14E−02 9.82E−03 Development_Activation of ERK by Alpha-1 adrenergic receptors 1.14E−02 9.82E−03 Development_PIP3 signaling in cardiac myocytes 1.28E−02 1.11E−02 Regulation of lipid metabolismjnsulin signaling:generic cascades 2.06E−02 1.28E−02 EGFR signaling pathway in Lung Cancer 1.28E−02 Stem cells_Scheme: FGF signaling in embryonic stem cell self-renewal and 2.06E−02 1.28E−02 differentiation Transcription_Transcription factor Tubby signaling pathways 1.32E−02 Cytoskeleton remodeling_Integrin outside-in signaling 1.43E−02 1.24E−02 HBV-dependent NF-kB and PI3K/AKT pathways leading to HCC 1.43E−02 Neuropeptide signaling in pancreatic cancer 1.43E−02 Immune response_IL-2 activation and signaling pathway 2.36E−02 1.43E−02 Development_Melanocyte development and pigmentation 1.43E−02 Pro-inflammatory action of Gastrin in gastric cancer 1.51E−02 1.31E−02 Development_GM-CSF signaling 1.51E−02 PI3K signaling in gastric cancer 1.60E−02 1.56E−03 Mucin expression in CF via TLRs, EGFR signaling pathways 1.60E−02 Stem cells_Scheme: Adult neurogenesis in the Subventricular Zone 1.64E−02 IGF signaling in HCC 2.87E−02 1.68E−02 1.46E−02 Development_WNT signaling pathway. Part 2 1.12E−03 1.77E−02 1.25E−05 4.19E−02 Development_FGFR signaling pathway 1.77E−02 1.53E−02 Proliferative action of Gastrin in gastric cancer 1.77E−02 Development_Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) 1.86E−02 1.94E−03 in control of skeletal myogenesis Immune response_CD28 signaling 1.86E−02 1.61E−02 ERBB family and HGF signaling in gastric cancer 1.86E−02 1.61E−02 PGE2 pathways in cancer 1.37E−03 1.95E−02 1.69E−02 3.47E−04 Transcription_Role of VDR in regulation of genes involved in osteoporosis 2.35E−02 Stem cells_Aberrant Wnt signaling in medulloblastoma stem cells 1.41E−02 2.36E−02 1.43E−03 Regulation of lipid metabolism_Regulation of acetyl-CoA carboxylase 2 activity 2.36E−02 in muscle Role of stellate cells in progression of pancreatic cancer 2.45E−02 Apoptosis and survival_NO signaling in survival 2.56E−02 Development_Gastrin in cell growth and proliferation 2.67E−02 3.50E−04 Transcription_Transcription regulation of aminoacid metabolism 1.77E−02 2.77E−02 2.50E−02 Dual role of BMP signaling in gastric cancer 2.14E−03 2.77E−02 Development_EGFR signaling pathway 2.78E−02 Cytoskeleton remodeling_TGF, WNT and cytoskeletal remodeling 3.40E−03 2.86E−02 7.77E−04 Muscle contraction_Regulation of eNOS activity in endothelial cells 2.90E−02 3.61E−03 n-3 Polyunsaturated fatty acid biosynthesis 2.90E−02 n-6 Polyunsaturated fatty acid biosynthesis 2.90E−02 Cell cycle_Regulation of G1/S transition (part 2) 2.98E−02 2.69E−02 Immune response_IL-10 signaling pathway 1.97E−02 2.98E−02 Apoptosis and survival_NGF signaling pathway 2.98E−02 Transcription_Role of Akt in hypoxia induced HIF1 activation 3.19E−02 2.89E−02 Inflammatory mechanisms of pancreatic cancerogenesis 3.26E−02 Immune response_Antigen presentation by MHC class I 3.42E−02 Immune response_Delta-type opioid receptor signaling in T-cells 3.64E−02 Apoptosis and survival_p53-dependent apoptosis 3.64E−02 Hedgehog signaling in gastric cancer 2.64E−02 3.64E−02 Glycine, serine, cysteine and threonine metabolism 3.85E−02 Immune response_IL-4 - antiapoptotic action 3.88E−02 Stem cells_Role of BMP signaling in embryonic stem cell neural differentiation 3.88E−02 Mechanisms of K-RAS addiction in lung cancer cells 3.88E−02 Apoptosis and survival_Granzyme A signaling 3.88E−02 Cell adhesion_Gap junctions 3.88E−02 Reproduction_GnRH signaling 3.91E−02 3.41E−02 Glycine, serine, cysteine and threonine metabolism/Rodent version 4.04E−02 Stem cells_Scheme: Histone H3 demethylases in stem cells 4.12E−02 Stem cells_Dopamine-induced transactivation of EGFR in SVZ neural stem cells 4.12E−02 Stem cells_Role of GSK3 beta in cardioprotection against myocardial infarction 4.36E−02 3.96E−02 Stem cells_H3K4 demethylases in stem cell maintenance 6.61E−04 4.36E−02 Signal transduction_Activin A signaling regulation 7.85E−05 4.61E−02 4.18E−02 Mucin expression in CF via IL-6, IL-17 signaling pathways 4.87E−02 4.42E−02 Stem cells_FGF2 signaling during embryonic stem cell differentiation 4.87E−02 Immune response_Role of the Membrane attack complex in cell survival 4.87E−02 Immune response_CXCR4 signaling via second messenger 4.87E−02 Signal transduction_Erk Interactions: Inhibition of Erk 4.87E−02 WNT signaling in gastric cancer 1.15E−03 2.50E−05 Stem cells_Fetal brown fat cell differentiation 7.54E−03 1.99E−04 Development_Role of IL-8 in angiogenesis 1.80E−03 2.56E−04 5.35E−03 E-cadherin signaling and its regulation in gastric cancer 4.61E−02 4.13E−04 WNT signaling in HCC 1.19E−02 6.21E−04 Regulation of lipid metabolism_Regulation of fatty acid synthase activity in 8.07E−04 hepatocytes Transcription_CREB pathway 8.96E−04 Development_WNT signaling pathway. Part 1. Degradation of beta-catenin in the 9.54E−03 9.42E−04 absence WNT signaling Development_WNT5A signaling 1.06E−03 Neurophysiological process_ACM regulation of nerve impulse 1.06E−03 immune response_MIF-JAB1 signaling 1.63E−03 G-protein signaling_Proinsulin C-peptide signaling 1.68E−03 Neurophysiological process_Kappa-type opioid receptor in transmission of nerve 3.13E−03 impulses Cell adhesion_Role of CDK5 in cell adhesion 3.32E−03 Cardiac Hypertrophy_NF-AT signaling in Cardiac Hypertrophy 3.82E−03 G-protein signaling_Regulation of CDC42 activity 4.11E−03 Cell cycle_ESR1 regulation of G1/S transition 4.11E−03 Development_Role of CDK5 in neuronal development 4.48E−03 Stem cells_Stimulation of differentiation of mouse embryonic fibroblasts into 2.12E−02 5.24E−03 adipocytes by extracellular factors Development_Beta-adrenergic receptors transactivation of EGFR 5.69E−03 Regulation of lipid metabolism_Regulation of lipid metabolism via LXR, NF-Y 9.95E−03 6.14E−03 2.27E−02 and SREBP Stem cells_Regulation of lung epithelial progenitor cell differentiation 1.30E−02 7.59E−03 Development_Ligand-dependent activation of the ESR1/AP-1 pathway 8.14E−03 Development_Ligand-independent activation of ESR1 and ESR2 9.23E−03 Immune response_IL-5 signalling 9.23E−03 Role of DNA methylation in progression of multiple myeloma 1.65E−02 9.23E−03 G-protein signaling_Regulation of cAMP levels by ACM 9.82E−03 3.11E−02 HIF-1 in gastric cancer 1.11E−02 Development_PDGF signaling via MAPK cascades 1.11E−02 Development_HGF signaling pathway 1.11E−02 Regulation of metabolism_Triiodothyronine and Thyroxine signaling 2.21E−02 1.17E−02 immune response_Function of MEF2 in T lymphocytes 1.31E−02 Transcription_Assembly of RNA Polymerase II preinitiation complex on TATA- 1.33E−02 less promoters Stem cells_Signaling pathways in embryonic hepatocyte maturation 1.38E−02 HCV-mediated liver damage and predisposition to HCC progression via p53 1.48E−02 Development_Endothelin-1/EDNRA signaling 1.53E−02 4.19E−02 Stem cells_Differentiation of white adipocytes 1.53E−02 Stem cells_H3K36 demethylation in stem cell maintenance 1.64E−02 Cell adhesion_Chemokines and adhesion 1.70E−02 Cytoskeleton remodeling_Cytoskeleton remodeling 1.82E−02 Transcription_Role of heterochromatin protein 1 (HP1) family in transcriptional 1.96E−02 silencing Delta508-CFTR traffic / Sorting endosome formation in CF 2.14E−02 Apoptosis and survival_Beta-2 adrenergic receptor anti-apoptotic action 2.14E−02 Immune response_IL-12 signaling pathway 2.14E−02 Transcription_PPAR Pathway 2.23E−02 Development_Alpha-2 adrenergic receptor activation of ERK 2.32E−02 Immune response_IFN alpha/beta signaling pathway 2.32E−02 Development_Glucocorticoid receptor signaling 2.32E−02 Inhibition of TGF-beta signaling in gastric cancer 2.14E−03 2.50E−02 Immune response_CD16 signaling in NK cells 3.06E−02 HGF signaling in pancreatic cancer 3.09E−02 Proteolysis_Putative SUMO-1 pathway 3.30E−02 NGF activation of NF-kB 3.30E−02 Apoptosis and survival_nAChR in apoptosis inhibition and cell cycle 2.64E−02 3.30E−02 progression Development_Slit-Robo signaling 3.51E−02 Development_Osteopontin signaling in osteoclasts 3.51E−02 Stem cells_Neovascularization of glioblastoma in response to hypoxia 3.73E−02 EGFR family signaling in pancreatic cancer 3.91E−02 Stem cells_WNT and Notch signaling in early cardiac myogenesis 4.66E−02 Role of osteoblasts in bone lesions formation in multiple myeloma 4.66E−02 Muscle contraction- GPCRs in the regulation of smooth muscle tone 4.87E−02 Development_SSTR2 in regulation of cell proliferation 4.90E−02 G-protein signaling_RAC1 in cellular process 4.61E−02 4.90E−02 Immune response_Regulation of T cell function by CTLA-4 4.90E−02 ENaC regulation in airways (normal and CF) 2.87E−02 ATP/ITP metabolism 2.13E−02 Translation_Opioid receptors in regulation of translation 1.59E−02 Delta508-CFTR traffic/ER-to-Golgi in CF 2.68E−03 GTP-XTP metabolism 3.97E−03 Transport_Aldosterone-mediated regulation of ENaC sodium transport 2.89E−02 Immune response_IL-7 signaling in T lymphocytes 9.95E−03 wtCFTR and delta508-CFTR traffic/Generic schema (norm and CF) 2.53E−02 Cell adhesion_Tight junctions 4.61E−02 2.05E−02 CTP/UTP metabolism 6.86E−04 Mechanisms of CAM-DR in multiple myeloma 7.44E−03 Apoptosis and survival_Role of lAP-proteins in apoptosis 4.79E−03 Development_BMP signaling 6.02E−03 Neurophysiological process_Netrin-1 in regulation of axon guidance 1.30E−02 2.61E−02 Immune response_IL-7 signaling in B lymphocytes 1.53E−02 Cell cycle_Sister chromatid cohesion 1.25E−02 Development_TGF-beta-dependent induction of EMT via SMADs 7.44E−03 Normal wtCFTR traffic/ER-to-Golgi 2.68E−03 Transport_RAN regulation pathway 7.05E−03 Immune response_IL-23 signaling pathway 1.77E−02 Transition of HCC cells to invasive and migratory phenotype 1.19E−02 Development_Regulation of CDK5 in CNS 2.40E−02 Development_CNTF receptor signaling 3.99E−02 Stem cells_Scheme: SMAD-dependent TGF-beta family signaling in 1.59E−02 embryonic stem cells Cell cycle_Spindle assembly and chromosome separation 6.02E−03 Stem cells_Extraembryonic differentiation of embryonic stem cells 4.29E−02 FGFR3 signaling in multiple myeloma 4.93E−02 Stem cells_Trophectoderm differentiation 1.77E−02 Development_PEDF signaling 2.36E−02 Signal transduction_PKA signaling 2.69E−02 3.72E−03 Stem cells_mGluR3 signaling in glioblastoma stem cells 4.05E−02 Stem cells_Embryonal epaxial myogenesis 1.54E−02 Blood coagulation_GPCRs in platelet aggregation 9.37E−03 Non-genomic signaling of ESR2 (membrane) in lung cancer cells 3.50E−02 Glycolysis and gluconeogenesis p. 1 3.24E−02 G-protein signaling_Regulation of p38 and JNK signaling mediated 2.38E−02 by G-proteins Membrane-bound ESR1: interaction with G-proteins signaling 3.91E−02 Inhibitory action of Lipoxin A4 on PDGF, EGF and LTD4 signaling 1.84E−02 Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway 2.61E−02 Development_Beta-adrenergic receptors regulation of ERK 3.37E−02 Development_S1P1 receptor signaling via beta-arrestin 1.74E−02 Regulation of lipid metabolism_Regulation of acetyl-CoA carboxylase 1 4.76E−03 activity in lipogenic tissue Signal transduction_cAMP signaling 1.60E−03 Immune response_PGE2 common pathways 4.05E−02 Muscle contraction_Relaxin signaling pathway 3.50E−02 Regulation of beta-adrenergic receptors signaling in pancreatic cancer 2.86E−02 Immune response_Histamine signaling in dendritic cells 3.77E−02 Regulation of lipid metabolism_Regulation of lipid metabolism by niacin and 3.11E−02 isoprenaline Development_Mu-type opioid receptor signaling via Beta-arrestin 9.40E−03 Glycolysis and gluconeogenesis (short map) 7.67E−03 Protein folding_Membrane trafficking and signal transduction of G-alpha (i) 5.94E−03 heterotrimeric G-protein Development S_1P3 receptor signaling pathway 2.86E−02 Regulation of CFTR activity (norm and CF) 4.93E−02 Angiogenesis in HCC 3.77E−02 Neurophysiological process_Dopamine D2 receptor signaling in CNS 3.37E−02 Development_Lipoxin inhibitory action on PDGF, EGF and LTD4 signaling 1.94E−02 Regulation of lipid metabolism_Regulation of acetyl-CoA carboxylase 1 4.76E−03 activity in keratinocytes Neurophysiological process_Melatonin signaling 2.86E−02 Blood coagulation_GPVI-dependent platelet activation 4.48E−02 Development_Role of Activin A in cell differentiation and proliferation 1.85E−03 G-protein signaling_S1P2 receptor signaling 1.94E−02 Apoptosis and survival_HTR1A signaling 3.77E−02 Immune response_TREM1 signaling pathway 4.63E−02 Muscle contraction_Role of kappa-type opioid receptor in heart 1.74E−02 Development_ERBB-family signaling 2.38E−02 Cholesterol and Sphingolipids transport/Influx to the early endosome in lung 1.45E−02 (normal and CF) Propionate metabolism p.2 9.74E−03 Regulation of metabolism_Bile acids regulation of glucose and lipid metabolism 2.16E−02 via FXR Reproduction_Progesterone-mediated oocyte maturation 2.50E−02 Apoptosis and survival_APRIL and BAFF signaling 2.27E−02 Chemotaxis_CXCR4 signaling pathway 1.84E−02 Neurophysiological process_HTR1A receptor signaling in neuronal cells 2.73E−02 Neurophysiological process_GABAergic neurotransmission 3.77E−02 Development_S1P1 signaling pathway 2.98E−02 Development_Delta- and kappa-type opioid receptors signaling via beta-arrestin 8.65E−03 Neurophysiological process_Mu-type opioid receptor-mediated analgesia 1.45E−02

Example 5: Persistent Parity-Related Decrease of p27+ Cells

This example demonstrates that the number of p27+ and Ki67+ cells are significantly lower in parous than in nulliparous breast tissues.

As discussed in Example CDKN1B encoding for p27, was one of the most significantly differentially expressed genes in CD44⁺ cells from nulliparous and parous (high in nulliparous) and also from control and BRCA1/2 parous tissues (high in BRCA1/2).

The global profiling results were validated in intact breast epithelium at the single cell level using multicolor immunofluorescence assays for the combined detection of CD24, CD44, and top differentially expressed genes. Genes were selected based on significance of difference between nulliparous and parous groups and antibody availability. A marked decrease was found in the expression of p27, Sox17, and Cox2 in parous compared to nulliparous samples. The levels of expression of these markers were lower in breast epithelial cells of parous women compared to nulliparous women (FIG. 18 and FIG. 19 ).

p27 has been reported to affect the number and proliferation of stem cells and progenitors in several organs. Thus, the decrease of p27+ cells in parous tissues may indicate that the number or proliferative potential of breast epithelial progenitors is decreased. To investigate this issue, immunofluorescence analysis was performed for Ki67, a proliferation marker expressed in cycling cells, alone and in combination with p27. Using this approach it was observed that the number of Ki67+ cells was significantly lower in parous samples and a small subset of cells was Ki67+p27+(FIG. 19 ).

The tissue samples used for the global profiling studies above (Example 3) were obtained from premenopausal women, since the protective effects of pregnancy against breast cancer are likely to be established early, even though they are manifested after menopause. However, to confirm that the parity-related differences detected in premenopausal women were maintained and could be detected even after menopause, the expression of p27, Sox17, and Cox2 was analyzed by immunofluorescence and immunohistochemistry in breast tissue samples from postmenopausal women. Although the observed differences between nulliparous and parous postmenopausal samples were less pronounced, the number of p27+ and Ki67+ cells were still significantly lower in parous than in nulliparous tissues (FIG. 20 ). This observation also suggested that the differences in the number of p27+ and Ki67+ cells between parous and nulliparous tissues in premenopausal women was not likely due to differences in the phase of the menstrual cycle between groups, as postmenopausal tissues showed similar differences for these markers.

Example 6: Link Between Parity-Related Differences and Mammographic Density

This example demonstrates that p27+ cells are a marker of both parity status and mammographic density, and a strong marker for breast cancer risk prediction.

Mammographic density is one of the most significant risk factors for breast cancer, yet its molecular basis is unknown. Mammographic density is higher in nulliparous women and declines after pregnancy, thus, some of the parity-related differences detected may also be linked to differences in mammographic density. To test this hypothesis, the expression levels of p27, Sox17, Cox2, and Ki67 were analyzed in biopsy samples obtained from high and low density areas of the same breast [Lin, et al. (2011) Breast Cancer Res Treat 128, 505-516]. The overall expression of Sox17, Cox2, p27, and Ki67 were not significantly different between low and high-density areas, but the number of p27+ cells was higher in high-density areas (FIG. 21 ). Thus, the number of p27+ cells is a marker of both parity status and mammographic density, and because both of these are linked to breast cancer risk, it can be used for breast cancer risk prediction.

Example 7: p27⁺ Cells are Quiescent Hormone-Responsive Cells with Progenitor Features

This example demonstrates that a subset of p27+ cells may represent quiescent hormone-responsive progenitors that are the potential cell-of-origin of breast cancer.

The mutually exclusive expression of Ki67 and p27 in breast epithelial cells with their concomitant decrease in parous compared to nulliparous women implied coordinated regulation and that they may represent actively cycling and quiescent cells with proliferative potential, respectively. Ovarian hormones are the best-understood regulators of breast epithelial cell proliferation and also breast cancer risk. Correlating with this, the gene expression data (Example 2) indicated a decrease in androgen receptor (AR) and AR targets in CD44⁺ cells from parous women (Table 4) and prior studies implied a decrease in ER+ breast epithelial cells in parous compared to nulliparous women. To explore the potential hormonal regulation of p27+ breast epithelial cells, the expression of ER, AR, and p27 was analyzed in breast tissue samples from women with varying parity and hormonal status. These included control nulliparous and parous women, BRCA1/2 mutation carriers, breast biopsy tissues from women in early (8-10 weeks) and late (22-26 weeks) stage of pregnancy, and premenopausal women in the follicular and luteal phases of the menstrual cycle or from women undergoing ovarian hyperstimulation prior to oocyte collection for in vitro fertilization (samples are collected at the time of oocyte collection). For each case, multiple different regions of the same slide or breast tissue sample were analyzed in order to minimize differences due to the known tissue heterogeneity even in the same woman. Interestingly, it was found that nearly all p27+ cells were also ER+, and their numbers were the highest in BRCA1/2 mutation carriers and the lowest in biopsy samples from pregnant women and after ovarian hyperstimulation, where both ovarian hormone and hCG (human choriogonadotropin) levels are the highest (FIG. 22 ). The frequencies of p27+ cells, ER+ cells, and p27+ER+ cells were also higher in control nulliparous compared to parous women and in follicular relative to luteal phase of the menstrual cycle (FIG. 22 ). Overall similar observations were made for AR (FIG. 23A), although the overlap between p27 and AR was less pronounced compared to that between p27 and ER (FIG. 23B). The high fraction of AR+ cells in BRCA1 mutation carriers is particularly interesting since AR is a genetic modifier of BRCA1-associated breast cancer risk.

To further investigate the relationship between the numbers of p27⁺ cells and ovarian hormone-induced breast epithelial cell proliferation, immunofluorescence analysis for p27 and Ki67 was performed in tissue samples with the highest differences in hormone levels. Correlating with prior data, the frequency of Ki67 cells was the highest in the luteal phase of the menstrual cycle when both estrogen and progesterone levels are high (FIG. 23B). Samples from early pregnancy had a lower fraction of proliferating Ki67⁺ cells and the numbers of these cells was the lowest in the follicular phase. The frequency of p27⁺ cells displayed an inverse correlation with that of Ki67⁺ cells: it was the highest in the follicular phase and lowest in biopsies from oocyte donors (breast tissue biopsies were taken at the time of oocyte collection) (FIG. 23B). Interestingly, a low but detectable fraction of p27⁺ cells was also Ki67⁺ in the luteal phase and early pregnancy, potentially marking proliferating progenitors in early G1 phase of the cell cycle when p27 and Ki67 can overlap. The differences in the frequency of p27⁺ and Ki67⁺ cells between the follicular and luteal phases was less significant in parous compared to nulliparous women in part due to the lower overall fractions of these cells in parous cases (FIG. 23C).

These results show that a subset of p27⁺ cells represent quiescent hormone-responsive luminal progenitors and that their frequency relates to the risk of breast cancer.

Example 8: Functional Validation of Parity-Related Differences in Signaling Pathways

This example demonstrates that the decreased activity of stem cell-related pathways following pregnancy lead to decreased Ki67+ and p27+ cells in parous women.

Several signaling pathways less active in CD44+ parous cells were related to stem cell maintenance and cell proliferation (FIG. 11 ). To investigate if inhibition of these pathways affects the number of proliferating cells, normal breast tissues were incubated in a tissue explant culture model with inhibitors or agonists of selected pathways (e.g., cAMP, EGFR, Cox2, Hh, TGFβ, Wnt, and IGFR) for 8-10 days. Inhibitors of irrelevant pathways (e.g., PARP inhibitor) as additional negative controls were also tested. For each case, three different pieces of breast tissue taken from different regions of the same breast were cultured, to minimize variability due to tissue heterogeneity. The number of p27+ cells and cellular proliferation based on bromodeoxyuridine (BrdU) incorporation (marks cells in S phase of the cell cycle) and Ki67 expression (marks cycling cells irrespective of cell cycle phase) was then assessed.

Tissue architecture and cellular viability were maintained and p27+, Ki67+, and BrdU+ cells were detected in all conditions. It was found that inhibition of cAMP, EGFR, Cox2, Hh, and IGFR signaling significantly (p<0.05) decreased the number of cells incorporating BrdU whereas the TGFBR inhibitor had the opposite effect (FIG. 24 ) Inhibition of EGFR and Cox2, and, to a lesser degree, Wnt and IGFR, decreased the fraction of Ki67+ cells, whereas the frequency of p27+ cells most pronouncedly decreased following IGFR and TGFBR inhibitor treatment. It was also confirmed that the compounds effectively inhibited the activity of the intended pathways (FIG. 25 and FIG. 26 ) and that the selected pathways were active in p27+ cells.

To determine whether the numbers and the proliferation of p27+ cells are regulated by ER and estrogen signaling, the fraction of p27+ and Ki67+ cells in tissue slices treated with varying concentrations of ovarian hormones or tamoxifen were analyzed. To correlate the tissue slices data with that was observed under physiologic conditions (FIG. 22 ), estrogen, progesterone, prolactin, and hCG hormone levels that mimic serum levels in the follicular or luteal phases of the menstrual cycle or in mid-pregnancy were used. It was observed that the numbers of p27+ cells were high in sections treated with concentrations of estrogen present in follicular phase and also following tamoxifen treatment, whereas it decreased following IGFR and TGFBR inhibitor treatment (FIG. 24 ). Cultures incubated with luteal phase and pregnancy level hormones (FIG. 26B and FIG. 26C). These data further demonstrated that a subset of p27+ cells are hormone-responsive luminal progenitors.

Most importantly, the expression of phosphoSmad2 (pSmad2), a key mediator of TGFβ signaling, demonstrated a nearly complete overlap with that of p27, implying that TGFβ is essential for maintaining these cells in quiescent stage possibly via modulating p27 (FIG. 25 ). These results imply that the decreased activity of these stem cell-related pathways following pregnancy may lead to decreased Ki67+ and p27+ cells in parous women. Furthermore, the data also suggested a direct role for these signaling pathways in regulating breast epithelial cell proliferation where TGF acts as a growth inhibitor and the other pathways are mitogenic.

Example 9: Relevance of Parity to Breast Cancer Risk and Prognosis

The present example demonstrates that parity influences both the risk and prognosis of ER+ breast tumors.

Based on the profiling data above (Example 3), it is presently demonstrated that breast epithelial cells with progenitor features are different in nulliparous and parous women. If these cells serve as cell-of-origin for breast cancer then breast tumors developing in parous and nulliparous women might also be different, and this might impact their gene expression profiles and clinical outcome. To test these hypotheses, the effect of parity on breast cancer-specific survival was investigated in the Nurses' Health Study (NHS). Overall, Kaplan Meier curves showed that there was no significant association between parity and breast cancer-specific survival (p=0.29). However, when the analysis was limited to ER+ tumors, it was found that nulliparous women had a suggestive worse survival compared with parous women (FIG. 27 ). In multivariate analysis there was still a marginally significant association among women with ER+ tumors, with nulliparous women having a nearly 30% increased risk of death from their disease (HR: 1.29, 95% CI: 0.98, 1.70; p=0.06). Assessing associations between age at first pregnancy and number of pregnancies gave similar results. In contrast, among women with ER− tumors, parity was not associated with breast cancer-specific survival (p=0.51). Thus, parity influences both the risk and prognosis of ER+ breast tumors.

Because pregnancy may not induce the same epigenetic and gene expression changes in all women, due to germline variations, it was next investigated if the parity-related gene expression signature (PAGES) in CD44+ cells might be a more useful prognostic marker than parity status alone. Thus, the expression of PAGES was analyzed in public breast cancer gene expression data with clinical outcome. The supervised principle component analysis (SPCA) was applied on one of the cohorts (Wang) as a training set (FIG. 28 ) to identify the subset of the PAGES with prognostic value followed by validation in three other cohorts (Desmedt et al., supra; Sotiriou et al., supra; van de Vijver et al., supra), the data for which are shown in FIGS. 29A-C ( ). In each dataset ER+ tumors, the tumor subtype affected by parity, and cases without systemic therapy were selected in order to avoid differences due to treatment. All patients in the training set had small (<2 cm), lymph node negative tumors at the time of diagnosis. Using this approach, parity/nulliparity-related gene signatures were identified that split patients into two distinct groups with significant survival difference. The genes included in the prognostic signature are summarized in Table 18, which shows the gene symbol, gene description, gene expression pattern (i.e., high in parous and nulliparous samples), and prognostic values (good or bad prognosis) for each of the genes. Interestingly, such prognostic signature was found among genes highly expressed in both nulliparous and parous samples and each set of genes could be further separated into good and bad signatures. These results reflect the complex relationship between pregnancy and breast cancer that involves both protective and tumor-promoting effects.

TABLE 18 Genes Included In Prognostic Parity/Nulliparity Gene Signature Gene Symbol Description Expression Prognosis A2M alpha-2-macroglobulin nulliparous bad ABLIM1 actin binding LIM protein 1 nulliparous bad ADNP activity-dependent neuroprotector homeobox parous bad APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 parous bad AQP1 aquaporin 1 (Colton blood group) nulliparous bad ARID5B AT rich interactive domain 5B (MRF1-like) nulliparous bad ASF1B ASF1 anti-silencing function 1 homolog B (S. cerevisiae) parous bad AZGP1 alpha-2-glycoprotein 1, zinc-binding pseudogene 1; alpha-2-glycoprotein 1, zinc- nulliparous bad binding B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; UDP- nulliparous bad GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 BACE2 beta-site APP-cleaving enzyme 2 nulliparous bad BIRC5 baculoviral IAP repeat-containing 5 parous bad C11orf60 chromosome 11 open reading frame 60 nulliparous bad C12orf48 chromosome 12 open reading frame 48 parous bad C19orf56 chromosome 19 open reading frame 56 nulliparous bad CCDC101 coiled-coil domain containing 101 nulliparous bad CCL2 chemokine (C-C motif) ligand 2 nulliparous bad CCNI cyclin I nulliparous bad CCT2 chaperonin containing TCP1, subunit 2 (beta) parous bad CD44 CD44 molecule (Indian blood group) nulliparous bad CENPA centromere protein A parous bad CHEK1 CHK1 checkpoint homolog (S. pombe) parous bad CIR1 corepressor interacting with RBPJ nulliparous bad CLPB ClpB caseinolytic peptidase B homolog (E. coli) parous bad CNN3 calponin 3, acidic nulliparous bad CSTB cystatin B (stefin B) nulliparous bad CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase nulliparous bad 1 CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase- nulliparous bad like CTPS CTP synthase parous bad CXCL12 chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) nulliparous bad DARC Duffy blood group, chemokine receptor nulliparous bad DDX39 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 parous bad DEF6 differentially expressed in FDCP 6 homolog (mouse) nulliparous bad DULLARD dullard homolog (Xenopus laevis) nulliparous bad DUSP4 dual specificity phosphatase 4 nulliparous bad EEF1A2 eukaryotic translation elongation factor 1 alpha 2 parous bad EFNA4 ephrin-A4 nulliparous bad EIF3G eukaryotic translation initiation factor 3, subunit G nulliparous bad F3 coagulation factor III (thromboplastin, tissue factor) nulliparous bad FBLN1 fibulin 1 nulliparous bad FBXO7 F-box protein 7 nulliparous bad FBXW4 F-box and WD repeat domain containing 4 nulliparous bad FLOT1 flotillin 1 nulliparous bad FTO fat mass and obesity associated nulliparous bad GAPVD1 GTPase activating protein and VPS9 domains 1 parous bad GGT5 gamma-glutamyltransferase 5 nulliparous bad GINS1 GINS complex subunit 1 (Psf1 homolog) parous bad GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 nulliparous bad GOLM1 golgi membrane protein 1 nulliparous bad GSTK1 glutathione S-transferase kappa 1 nulliparous bad GSTP1 glutathione S-transferase pi 1 nulliparous bad GYPC glycophorin C (Gerbich blood group) nulliparous bad HEATR2 HEAT repeat containing 2 parous bad HIGD2A HIG1 hypoxia inducible domain family, member 2A nulliparous bad HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 nulliparous bad HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 nulliparous bad IGFBP4 insulin-like growth factor binding protein 4 nulliparous bad IMP3 IMPS, U3 small nucleolar ribonucleoprotein, homolog (yeast) nulliparous bad INPP1 inositol polyphosphate-1-phosphatase nulliparous bad ITM2A integral membrane protein 2A nulliparous bad JOSD1 Josephin domain containing 1 nulliparous bad KIAA0101 KIAA0101 parous bad KIAA0406 KIAA0406 parous bad LITAF lipopolysaccharide-induced TNF factor nulliparous bad LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 nulliparous bad LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) nulliparous bad MCF2L MCF.2 cell line derived transforming sequence-like parous bad MGMT O-6-methylguanine-DNA methyltransferase nulliparous bad MNAT1 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) parous bad NAP1L1 nucleosome assembly protein 1-like 1 nulliparous bad NFYC nuclear transcription factor Y, gamma nulliparous bad NUPR1 nuclear protein, transcriptional regulator, 1 nulliparous bad PALM paralemmin nulliparous bad PIK3IP1 phosphoinositide-3-kinase interacting protein 1 nulliparous bad PNRC1 proline-rich nuclear receptor coactivator 1 nulliparous bad POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) parous bad PPM1D protein phosphatase 1D magnesium-dependent, delta isoform parous bad PRC1 protein regulator of cytokinesis 1 parous bad PSAP prosaposin nulliparous bad PYCRL pyrroline-5-carboxylate reductase-like parous bad RACGAP1 Rac GTPase activating protein 1 pseudogene; Rac GTPase activating protein 1 parous bad RCOR3 REST corepressor 3 nulliparous bad RECQL4 RecQ protein-like 4 parous bad RNF146 ring finger protein 146 nulliparous bad RPL15 ribosomal protein L15 pseudogene 22; ribosomal protein L15 pseudogene 18; nulliparous bad ribosomal protein L15 pseudogene 17; ribosomal protein L15 pseudogene 3; ribosomal protein L15 pseudogene 7; ribosomal protein L15 RPL22 ribosomal protein L22 pseudogene 11; ribosomal protein L22 nulliparous bad RPLP2 ribosomal protein, large, P2 pseudogene 3; ribosomal protein, large, P2 nulliparous bad RPS6KA1 ribosomal protein S6 kinase, 90 kDa, polypeptide 1 nulliparous bad RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) parous bad SCRIB scribbled homolog (Drosophila) parous bad SEPP1 selenoprotein P, plasma, 1 nulliparous bad SLC17A9 solute carrier family 17, member 9 parous bad SLC25A28 solute carrier family 25, member 28 nulliparous bad SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), nulliparous bad member 6 SLC35B1 solute carrier family 35, member B1 parous bad SPC25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) parous bad SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 parous bad STMN1 stathmin 1 parous bad SYNGR3 synaptogyrin 3 parous bad TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) parous bad TNFRSF11 tumor necrosis factor receptor superfamily, member 11b nulliparous bad TNNT3 troponin T type 3 (skeletal, fast) nulliparous bad TPT1 similar to tumor protein, translationally-controlled 1; tumor protein, translationally- nulliparous bad controlled 1 TRIP10 thyroid hormone receptor interactor 10 nulliparous bad TSPAN7 tetraspanin 7 nulliparous bad TXNIP thioredoxin interacting protein nulliparous bad UBE3C ubiquitin protein ligase E3C parous bad UCKL1 uridine-cytidine kinase 1-like 1 parous bad USP32 similar to TBC1 domain family, member 3; ubiquitin specific peptidase 32 parous bad YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta nulliparous bad polypeptide ZC3H3 zinc finger CCCH-type containing 3 parous bad ZFP36L1 zinc finger protein 36, C3H type-like 1 nulliparous bad ZFP36L2 zinc finger protein 36, C3H type-like 2 nulliparous bad ACY1 aminoacylase 1 parous good AGGF1 angiogenic factor with G patch and FHA domains 1 parous good AGK acylglycerol kinase nulliparous good AMIGO2 adhesion molecule with Ig-like domain 2 nulliparous good ANKRD46 ankyrin repeat domain 46 nulliparous good APOD apolipoprotein D parous good APOL1 apolipoprotein L, 1 parous good APOL3 apolipoprotein L, 3 parous good ARHGAP1 Rho GTPase activating protein 11B; Rho GTPase activating protein 11A parous good ATG4B ATG4 autophagy related 4 homolog B (S. cerevisiae) parous good AZIN1 antizyme inhibitor 1 nulliparous good B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) nulliparous good C13orf34 chromosome 13 open reading frame 34 parous good CBX3 similar to chromobox homolog 3; chromobox homolog 3 nulliparous good CD79A CD79a molecule, immunoglobulin-associated alpha parous good CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 parous good CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 nulliparous good CNBP CCHC-type zinc finger, nucleic acid binding protein parous good CNIH cornichon homolog (Drosophila) nulliparous good COBRA1 cofactor of BRCA1 nulliparous good COQ2 coenzyme Q2 homolog, prenyltransferase (yeast) nulliparous good COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 nulliparous good CSTF1 cleavage stimulation factor, 3′ pre-RNA, subunit 1, 50 kDa nulliparous good CYC1 cytochrome c-1 nulliparous good DCPS decapping enzyme, scavenger parous good DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit nulliparous good DYNLL1 dynein, light chain, LC8-type 1 parous good E2F5 E2F transcription factor 5, p130-binding nulliparous good EFR3A EFR3 homolog A (S. cerevisiae) nulliparous good EIF3J eukaryotic translation initiation factor 3, subunit J parous good ERO1L ERO1-like (S. cerevisiae) nulliparous good FAM164A family with sequence similarity 164, member A nulliparous good FAM55C family with sequence similarity 55, member C parous good FEN1 flap structure-specific endonuclease 1 nulliparous good FLRT3 fibronectin leucine rich transmembrane protein 3 nulliparous good GLG1 golgi apparatus protein 1 parous good GUF1 GUF1 GTPase homolog (S. cerevisiae) parous good HAUS5 HAUS augmin-like complex, subunit 5 parous good HDGFRP3 hepatoma-derived growth factor, related protein 3 nulliparous good HLA-B major histocompatibility complex, class I, C; major histocompatibility complex, class I, B parous good HLA-DOB major histocompatibility complex, class II, DO beta parous good HMGB2 high-mobility group box 2 nulliparous good INPP5D inositol polyphosphate-5-phosphatase, 145 kDa parous good INVS inversin parous good ITCH itchy E3 ubiquitin protein ligase homolog (mouse) parous good KCNG2 potassium voltage-gated channel, subfamily G, member 2 parous good KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 nulliparous good KIAA0391 KIAA0391 nulliparous good LAPTM4B lysosomal protein transmembrane 4 beta nulliparous good LARP4 La ribonucleoprotein domain family, member 4 nulliparous good LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), parous good member 1 MAP3K7IP mitogen-activated protein kinase kinase kinase 7 interacting protein 1 parous good METT11D1 methyltransferase 11 domain containing 1; similar to methyltransferase 11 domain parous good containing 1 isoform 2 MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); nulliparous good translocated to, 11 MLX MAX-like protein X parous good MTDH metadherin nulliparous good NDRG4 NDRG family member 4 nulliparous good NDUFA4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9 kDa nulliparous good NFS1 NFS1 nitrogen fixation 1 homolog (S. cerevisiae) nulliparous good NRAS neuroblastoma RAS viral (v-ras) oncogene homolog nulliparous good P4HA2 prolyl 4-hydroxylase, alpha polypeptide II nulliparous good PHF1 PHD finger protein 1 parous good PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide parous good PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 nulliparous good PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 parous good PNP nucleoside phosphorylase nulliparous good PNPLA2 patatin-like phospholipase domain containing 2 parous good PPP1CC protein phosphatase 1, catalytic subunit, gamma isoform nulliparous good PPP3R1 protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform nulliparous good PRPF31 PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) nulliparous good PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 nulliparous good PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 nulliparous good PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 nulliparous good PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 nulliparous good PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 nulliparous good PUF60 poly-U binding splicing factor 60 KDa nulliparous good RALA v-ral simian leukemia viral oncogene homolog A (ras related) nulliparous good RBBP7 retinoblastoma binding protein 7 nulliparous good RFC3 replication factor C (activator 1) 3, 38 kDa nulliparous good RHBDL1 rhomboid, veinlet-like 1 (Drosophila) parous good RINT1 RAD50 interactor 1 parous good RNASEH1 ribonuclease H1 parous good RNF125 ring finger protein 125 parous good RPS11 ribosomal protein S11 pseudogene 5; ribosomal protein S11 parous good RPS6 ribosomal protein S6 pseudogene 25; ribosomal protein S6; ribosomal protein S6 parous good pseudogene 1 RRAGA Ras-related GTP binding A parous good SAPS3 SAPS domain family, member 3 parous good SCNN1B sodium channel, nonvoltage-gated 1, beta nulliparous good SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) nulliparous good SKA1 chromosome 18 open reading frame 24 parous good SLC25A32 solute carrier family 25, member 32 nulliparous good SRP19 signal recognition particle 19 kDa nulliparous good ST20 suppressor of tumorigenicity 20 parous good STAU1 staufen, RNA binding protein, homolog 1 (Drosophila) nulliparous good STX3 syntaxin 3 nulliparous good THAP4 THAP domain containing 4 parous good TIMELESS timeless homolog (Drosophila) nulliparous good TMCO1 transmembrane and coiled-coil domains 1 nulliparous good TMED9 transmembrane emp24 protein transport domain containing 9 nulliparous good TMEM158 transmembrane protein 158 nulliparous good TMEM222 transmembrane protein 222 parous good TOB1 transducer of ERBB2, 1 nulliparous good TSPAN13 tetraspanin 13 nulliparous good TTC38 tetratricopeptide repeat domain 38 parous good TUBA1C tubulin, alpha 1c nulliparous good TXNDC9 thioredoxin domain containing 9 nulliparous good UBA2 ubiquitin-like modifier activating enzyme 2 nulliparous good UQCRB similar to ubiquinol-cytochrome c reductase binding protein nulliparous good WDR12 WD repeat domain 12 nulliparous good XPOT exportin, tRNA (nuclear export receptor for tRNAs); similar to Exportin-T (tRNA nulliparous good exportin) (Exportin(tRNA)) YEATS4 YEATS domain containing 4 nulliparous good YIF1A Yip1 interacting factor homolog A (S. cerevisiae) nulliparous good ZDHHC14 zinc finger, DHHC-type containing 14 parous good ZFAND1 zinc finger, AN1-type domain 1 nulliparous good ZNF217 zinc finger protein 217 nulliparous good ZNF264 zinc finger protein 264 nulliparous good ZNF304 zinc finger protein 304 nulliparous good ZNF706 zinc finger protein 706 nulliparous good ZWINT ZW10 interactor nulliparous good

Example 10: Parity-Associated Decrease in Mammary Epithelial Progenitors and Breast Tumor Initiation

The data described in the Examples above support the hypothesis that a decrease in the number and proliferative potential of luminal progenitors in parous women directly relates to a decrease in breast cancer risk for both ER+ and ER− breast cancers, and that this effect is dependent on the age at first full-term pregnancy. A mathematical model of the dynamics of proliferating mammary epithelial cells was designed that can accumulate the changes leading to cancer initiation. In the model, described in detail below, two types of cells were considered: (1) a self-renewing population of stem cells and, (2) a population of proliferating hormone-responsive luminal progenitors that result from the differentiation of these stem cells.

Mathematical Modeling:

Simulations were initiated at menarche and continued until cancer initiation or death, as depicted in the timeline in FIG. 30 . The effect of pregnancy at varying times from menarche through right before menopause on cancer initiation was tested and compared against the nulliparous cancer initiation risk. The robustness of the simulation over varying numbers of stem cells per terminal end duct, additional proliferative capacities resulting from pregnancy, and rates of asymmetric stem cell division were then tested.

The dynamics of stem cells in the breast ductal system was first studied. Given the population structure inherent to breast ducts, it was assumed that the stem cells in each duct act independently. As such, the dynamics of a single duct within the breast was investigated since the total probability of cancer initiation is given by the probability per niche times the number of niches. Thus, the relative likelihood of cancer initiation is not altered by considering only one niche. The overall number of stem cells in the breast is on the order of 5 to 10 cells per duct, and this number was denoted by N. A fundamental time step of this system to be dictated by the division time of stem cells, t_(step), which varies during pregnancy, was defined. In previously published in vivo experiments, the mean cell cycle length of benign breast hyperplasia cells was approximately 162 hours per cell. It was assumed that even benign breast hyperplasia cells divide faster than stem cells; thus, using t_(step)=162 hours as the average stem cell cycle length when not pregnant may be an overestimation of the number of stem cell divisions that occur in the normal breast. Within a duct, a single stem cell is randomly chosen to divide during each time step proportional to the fitness of the cell, following a stochastic process known as the Moran model (see, Moran, P. A. P. (1962). The statistical processes of evolutionary theory (Oxford: Clarendon Press). National Center for Health Statistics (US)(2012). Health, United States, 2011: With Special Feature on Socioeconomic Status and Health (Hyattsville, Md.)). According to this model, the divided cell is replaced by one of the daughter cells of the division, while the other daughter replaces another stem cell that was randomly selected from the population. Use of this model ensured preservation of homeostasis in the normal breast cell population. For each cell division, a single mutation was allowed to arise in one of the two daughter cells of the division.

In the mature breast, stem cells divide primarily to maintain cellular integrity. However, differentiating events do occur, although rarely. In this model, with probability p, cell division in the current time step was allowed to be asymmetric, producing one stem daughter cell to maintain the stem cell population and one progenitor daughter. Since the exact rate of differentiation is unknown, p=10⁻¹ to 10⁻³ was tested. With the remaining 1−p probability, the stem cell division is symmetric and followed the usual Moran division dynamics. In each time step thereafter, all of the cells resulting from the progenitor daughter divided and differentiated further until a total of z cell divisions were accumulated. We set z=10, to fit data from mouse fat pad depletion experiments (see, Kordon, E. C., and Smith, G. H. (1998). An entire functional mammary gland may comprise the progeny from a single cell. Development 125, 1921-1930.) After z_(pre) divisions, the cells were considered differentiated and, at this point, they were no longer included in the cells considered in the mathematical model. Thus, in the wild-type system, there were N stem cells per duct and 2^(z+1)−1 progenitor cells per differentiation cascade. FIG. 34 describes the temporal dynamics of the system.

During each cell division, genetic alterations contributing to cancer initiation may arise. A number n_(mut) of mutations were considered that, when combined, result in a single cell leading to cancer initiation. These mutations could be any of the many mutations commonly found in breast cancer with initiation potential; however, it was assumed that only a single mutational hit was necessary to (in)activate the gene. The simulation was tested with mutation rates on the order of 10⁻⁵ mutations per gene per cell division to limit the required number of simulations for detection to a reasonable number; however, results remained consistent even at lower mutation rates. The following mutational effects were assumed for each mutation: in stem cells, mutant cells had a relative fitness of f_(mut)=1.1, i.e. a fitness increase of 10%, resulting in an increased probability of dividing, while mutant progenitor cells divided an additional z_(mut)=1 times (FIG. 34 ). Since the number of stem cells per duct is small, the fitness of mutant alleles has little effect on cancer initiation probabilities, as the fixation time of mutations is much smaller than the mutation accumulation time (see, Hambardzumyan, D., Cheng, Y. K., Haeno, H., Holland, E. C., and Michor, F. (2011). The probable cell of origin of NF1- and PDGF-driven glioblastomas. PLoS One 6, e24454). Thus, ignoring the specific value of f_(mut) is justified. These assumptions presume that the mutations primarily act to increase the proliferation rate of cells. Mutant fitness values were considered to be multiplicative while mutant progenitor division capacity was considered to be additive. Thus, the relative fitness of a stem cell with in mutations was f_(mut) ^(n) and the number of divisions a mutant progenitor with n mutations was z+n*z_(mut). Additionally, progenitor cells must accumulate some propensity towards self-renewal: a parameter γ=γ_(base)−i*γ_(step) was defined as the probability of a progenitor cell at differentiation level 0≤i≤z+n*z_(mut) acquiring self-renewal. Cancer initiation was defined as a single cell that accumulated all required mutations and either retained or acquired the ability to self-renew, either through being a stem cell or through acquiring a genetic or epigenetic self-renewal event.

The phenotypic alterations that occur in the breast during pregnancy and as a result of pregnancy were considered. For the purposes of this simulation, the 280 day period of time for the pregnancy itself was considered as the time period during which parameters are altered by pregnancy. It has been previously published that pregnancy results in terminal differentiation of progenitor cells into milk producing cells as well as increased proliferation of cells. To model these effects, further differentiation of progenitor cells during pregnancy by an additional z_(preg) differentiation levels, and a decrease in the cell cycle length of stem cells was allowed (FIG. 34 ). According to several groups, there is a 4.5 to 8.5-fold increase in Ki67+ cells during pregnancy. Thus, a 4-fold to 8-fold increase in progenitor cells during pregnancy was allowed, corresponding to p_(preg)=2 to 3. The remaining ˜1.1 fold increase in proliferation was modeled as a decrease in stem cell cycle length to t_(step,preg)=147 hours. Additionally, as described in the Examples, above, there was also a decrease in the number of proliferative progenitors after pregnancy: this change was simulated in population structure by decreasing the number of differentiation levels in the progenitor hierarchy by z_(post). The experiments showed a 2-3 fold drop in p27⁺ expressing progenitor cells, which would correspond to z_(post)=1.

The simulation spanned from menarche to death or initiation of cancer within the duct. As such, the total simulation time was calculated from the average women's life expectancy in the United States, which was 80.9 years in 2009, and the average age of menarche, which ranged between 12.4-12.7 years of age for differing age groups in 2002 (FIG. 34 ). The mean age of menarche between the groups was used, which was 12.6 years, and thus resulted in a total of 68.3 years of simulation time. The effects of pregnancy occurring at four roughly equidistant time points, t_(preg) was tested: immediately following menarche, time of first pregnancy at the average age of 25.4 in 2010, immediately before menopause at the average age of 51.3 in 1998, and halfway between average first pregnancy and menopause at the age of 38.3. All time points were tabulated from the most recent government-provided data. The effects of varying the simulation parameters independently for each pregnancy age t_(preg) were tested. All fixed value parameters and the values of all other parameters are listed in the tables below.

TABLE 19 Fixed parameter values t_(total) t_(step) t_(step,preg) (years) f_(mut) γ γ_(step) μ (h) (h) z z_(mut) z_(post) 68.3 1.1 0.1 0.005 2 × 10⁻⁵ 162 147 10 1 −1 Legend: Parameters that remained unchanged throughout all simulations are shown.

TABLE 20 Range of parameter values investigated t_(preg) N n_(mut) p z_(preg) 0 5 1 10⁻³ 2 12.8 8 2 10 ⁻² 3 25.7 10 10⁻¹ 38.7 Legend: For each parameter of interest, multiple values were tested. Values defaulted to the numbers in bold.

In the schematic depicted in FIG. 31 , initially, there are N wild-type stem cells (top of schematic), which give rise to a differentiation cascade of 2^(z+1)−1 wild-type luminal progenitor cells (triangular, lower region). At each time step, all progenitor cells as well as one randomly selected stem cell divide. With probability α, the stem cell divides symmetrically and one daughter cell replaces another randomly chosen stem cell. With probability 1−α, the stem cell divides asymmetrically and one daughter cell remains a stem cell while the other daughter cell becomes committed to the progenitor population. Regardless of the dividing stem cell's fate, all existing progenitor cells divide symmetrically for a total of z times to give rise to successively more differentiated cells (progressively darker shades of gray) before becoming terminally differentiated. Darkening gray gradations refer to successively more differentiated cells and serve to clarify a single time step of the stochastic process.

In FIG. 32 , the acquisition of mutations leading to breast cancer initiation all result in an increased relative fitness (i.e., growth rate) f_(mut) in stem cells (“SC”) as compared to wild-type cells (“WT”) and an additional number of divisions z_(mut) progenitor cells can undergo before terminally differentiating.

In FIG. 33 , during pregnancy, progenitor cells experience an expansion in proliferative capacity through an additional number of division z_(preg) in order to form terminally differentiated milk-producing cells (dotted triangle) and a decrease in cell cycle length.

The effect of pregnancy on breast cancer per duct (expressed as the relative probability of cancer initiation) as compared to nulliparous simulations initiation at varying times after menarche was tested and compared to the risk of tumor initiation in nulliparous women. Default values were N=8, p=10⁻², z_(preg)=2 (FIG. 34 ). It was observed that the relative likelihood of initiation increased with later pregnancy. The robustness of the simulation over varying numbers of stem cells per terminal end duct, additional proliferative capacities resulting from pregnancy, and rates of asymmetric stem cell division were tested (FIGS. 35-37 ). The relative likelihood of cancer initiation was then compared with pregnancy occurring at four different time points during childbearing years as compared to nulliparous simulations. It was found that the probability of cancer initiation in a duct increases as the age at first pregnancy increases. Furthermore, these simulations showed that differences in the numbers of luminal epithelial progenitors with proliferative potential is the most probable explanation for differences in breast cancer risk due to reproductive (e.g., parity) and genetic (e.g., BRCA1/2 germline mutation) factors.

In summary, it was found that both increasing numbers of stem cells per duct and increasing rates of asymmetric stem cell division increase the rate of cancer initiation per duct. Also, as expected, changes in the proliferative capacity of progenitor cells during pregnancy had no effect in the nulliparous state. The relative likelihood of cancer initiation was then compared with pregnancy occurring at four different time points during a woman's childbearing years as compared to the nulliparous simulations. It was found that the probability of cancer initiation in a duct increases as the age of first pregnancy increases within the range of all simulated parameters. Additionally, the probability of cancer initiation is greater in nulliparous situations than in all pregnancy simulations. Interestingly, cancer initiation from the stem cell population decreases with age of first pregnancy while initiation from progenitors increases. Some of the cancers that were considered as initiated from the progenitor population may potentially have had a stem initiation event occur afterwards, and simulations where progenitor initiation occurred are also those where fixation of the first mutation in the stem population was likely.

A number of embodiments of the invention have been described. Nevertheless, it will be understood that various modifications may be made without departing from the spirit and scope of the invention. It is further to be understood that all values are approximate, and are provided for description. Accordingly, other embodiments are within the scope of the following claims. 

What is claimed is:
 1. A method of treating a human subject who has not been diagnosed with breast cancer, wherein the method comprises: (a) providing a first breast tissue sample from a first human subject who has not been diagnosed with breast cancer and has not undergone a therapy for treatment of breast cancer; (b) measuring a relative frequency of p27+ breast epithelial cells and a relative frequency of Ki67+ breast epithelial cells in the first breast tissue sample from the first human subject, wherein a relative frequency is calculated as number or % of cells positive for a given marker compared to all breast epithelial cells counted; and (c) administering a prophylaxis, performing diagnostic assays, and/or periodically monitoring the health of the first human subject having a higher relative frequency of p27+ breast epithelial cells and a higher relative frequency of Ki67+ breast epithelial cells in the first breast tissue sample as compared to a second human subject having a lower relative frequency of p27+ breast epithelial cells and a lower relative frequency of Ki67+ breast epithelial cells in a second breast tissue sample, wherein the second human subject is a control subject known to not have or develop a breast cancer.
 2. The method of claim 1, wherein the first human subject has a BRCA1 mutation.
 3. The method of claim 1, wherein the first human subject has a BRCA2 mutation.
 4. The method of claim 1, further comprising administering to the first human subject a composition comprising an inhibitor of a pathway active in p27+ and/or Ki67+ normal breast epithelial cells.
 5. The method of claim 4, wherein the pathway is selected from the group consisting of cytoskeleton remodeling, chemokines, androgen signaling, cell adhesion, and Wnt signaling.
 6. The method of claim 5, wherein the pathway includes a mediator molecule selected from the group consisting of cyclic AMP (cAMP), epidermal growth factor receptor (EGFR), cyclooxygenase-2 (Cox2), Hedgehog (Hh), Transforming growth factor β receptor (TGFBR), and insulin growth factor receptor (IGFR).
 7. The method of claim 5, wherein the inhibitor selectively targets p27+ breast epithelial cells and/or Ki67+ breast epithelial cells in normal breast tissue.
 8. The method of claim 7, wherein the cells selectively targeted by the inhibitor are also ER+.
 9. The method of claim 1, wherein the first human subject has not been diagnosed with an ER+ breast cancer.
 10. The method of claim 1, wherein the diagnostic assay that is performed on the first human subject in step (c) comprises clinical breast exam, mammography, or MRI. 